1. Medchain: Bridging the Gap Between LLM Agents and Clinical Practice through Interactive Sequential Benchmarking
- Author
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Liu, Jie, Wang, Wenxuan, Ma, Zizhan, Huang, Guolin, SU, Yihang, Chang, Kao-Jung, Chen, Wenting, Li, Haoliang, Shen, Linlin, and Lyu, Michael
- Subjects
Computer Science - Computation and Language ,Computer Science - Artificial Intelligence - Abstract
Clinical decision making (CDM) is a complex, dynamic process crucial to healthcare delivery, yet it remains a significant challenge for artificial intelligence systems. While Large Language Model (LLM)-based agents have been tested on general medical knowledge using licensing exams and knowledge question-answering tasks, their performance in the CDM in real-world scenarios is limited due to the lack of comprehensive testing datasets that mirror actual medical practice. To address this gap, we present MedChain, a dataset of 12,163 clinical cases that covers five key stages of clinical workflow. MedChain distinguishes itself from existing benchmarks with three key features of real-world clinical practice: personalization, interactivity, and sequentiality. Further, to tackle real-world CDM challenges, we also propose MedChain-Agent, an AI system that integrates a feedback mechanism and a MCase-RAG module to learn from previous cases and adapt its responses. MedChain-Agent demonstrates remarkable adaptability in gathering information dynamically and handling sequential clinical tasks, significantly outperforming existing approaches. The relevant dataset and code will be released upon acceptance of this paper.
- Published
- 2024