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3. NLRs derepress MED10b- and MED7-mediated repression of jasmonate-dependent transcription to activate immunity.

Author

Wu, Qian, Tong, Cong, Chen, Zhengqiang, Huang, Shen, Zhao, Xiaohui, Hong, Hao, Li, Jia, Feng, Mingfeng, Wang, Huiyuan, Xu, Min, Yan, Yuling, Cui, Hongmin, Shen, Danyu, Ai, Gan, Xu, Yi, Li, Junming, Zhang, Hui, Huang, Changjun, Zhang, Zhongkai, Dong, Suomeng, Wang, Xuan, Zhu, Min, Tao, Xiaorong, and Dinesh-Kumar, Savithramma

Subjects
Mediator complex, NLRs, Sw-5b, effector-triggered immunity, Plant Immunity, Cyclopentanes, Transcription Factors, Mediator Complex, Arabidopsis Proteins
Abstract

Plant intracellular nucleotide-binding domain, leucine-rich repeat-containing receptors (NLRs) activate a robust immune response upon detection of pathogen effectors. How NLRs induce downstream immune defense genes remains poorly understood. The Mediator complex plays a central role in transducing signals from gene-specific transcription factors to the transcription machinery for gene transcription/activation. In this study, we demonstrate that MED10b and MED7 of the Mediator complex mediate jasmonate-dependent transcription repression, and coiled-coil NLRs (CNLs) in Solanaceae modulate MED10b/MED7 to activate immunity. Using the tomato CNL Sw-5b, which confers resistance to tospovirus, as a model, we found that the CC domain of Sw-5b directly interacts with MED10b. Knockout/down of MED10b and other subunits including MED7 of the middle module of Mediator activates plant defense against tospovirus. MED10b was found to directly interact with MED7, and MED7 directly interacts with JAZ proteins, which function as transcriptional repressors of jasmonic acid (JA) signaling. MED10b-MED7-JAZ together can strongly repress the expression of JA-responsive genes. The activated Sw-5b CC interferes with the interaction between MED10b and MED7, leading to the activation of JA-dependent defense signaling against tospovirus. Furthermore, we found that CC domains of various other CNLs including helper NLR NRCs from Solanaceae modulate MED10b/MED7 to activate defense against different pathogens. Together, our findings reveal that MED10b/MED7 serve as a previously unknown repressor of jasmonate-dependent transcription repression and are modulated by diverse CNLs in Solanaceae to activate the JA-specific defense pathways.

Published
2023

8. A randomized-controlled trial of ischemia-free liver transplantation for end-stage liver disease

Author

Guo, Zhiyong, Zhao, Qiang, Jia, Zehua, Huang, Changjun, Wang, Dongping, Ju, Weiqiang, Zhang, Jian, Yang, Lu, Huang, Shanzhou, Chen, Maogen, Zhu, Xiaofeng, Hu, Anbin, Ma, Yi, Wu, Linwei, Chen, Yinghua, Han, Ming, Tang, Yunhua, Wang, Guodong, Wang, Linhe, Li, Lifen, Xiong, Wei, Zhang, Zhiheng, Shen, Yuekun, Tang, Zhaoxia, Zhu, Caihui, Chen, Xiaoxiang, Hu, Xiaoguang, Guo, Yiwen, Chen, Honghui, Ma, Yihao, Zhang, Tao, Huang, Shunwei, Zeng, Ping, Lai, Simei, Wang, Tielong, Chen, Zhitao, Gong, Jinlong, Yu, Jia, Sun, Canhui, Li, Chang, Tan, Haiyi, Liu, Yao, Dong, Yuqi, Sun, Chengjun, Liao, Bing, Ren, Jun, Zhou, Zhenhai, Andrea, Schlegel, Björn, Nashan, Cai, Changjie, Gong, Fengqiu, Rong, Jian, Huang, Wenqi, Guan, Xiangdong, Clavien, Pierre-Alain, Stefan, Tullius G., Huang, Jiefu, and He, Xiaoshun

Published
2023
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10. Astaxanthin Alleviates Autoimmune Hepatitis by Modulating CD8+ T Cells: Insights From Mass Cytometry and Single‐Cell RNA Sequencing Analyses.

Author

He, Yuting, Ding, Mingjie, Zhang, Jiakai, Huang, Changjun, Shi, Jihua, Wang, Yun, Tao, Ruolin, Wu, Zeyu, and Guo, Wenzhi

Subjects
RNA sequencing, AUTOIMMUNE hepatitis, T cells, CELL physiology, TRANSCRIPTION factors, ASTAXANTHIN
Abstract

Astaxanthin (ASX) is an oxygen‐containing non‐vitamin A carotenoid pigment. However, the role of ASX in autoimmune hepatitis (AIH) remains unclear. In this study, a mouse model of AIH is established induced by concanavalin A (ConA). Mass cytometry and single‐cell RNA sequencing (scRNA‐seq) are used to analyze the potential role of ASX in regulating the immune microenvironment of AIH. ASX treatment effectively alleviated liver damage induced by ConA and downregulated pro‐inflammatory cytokines production in mice. Mass cytometry and scRNA‐seq analyses revealed a significant increase in the number of CD8+ T cells following ASX treatment. Functional markers of CD8+ T cells, such as CD69, MHC II, and PD‐1, are significantly downregulated. Additionally, specific CD8+ T cell subclusters (subclusters 4, 13, 24, and 27) are identified, each displaying distinct changes in marker gene expression after ASX treatment. This finding suggests a modulation of CD8+ T cell function by ASX. Finally, the key transcription factors for four subclusters of CD8+ T cells are predicted and constructed a cell‐to‐cell communication network based on receptor‐ligand interactions probability. In conclusion, ASX holds the potential to ameliorate liver damage by regulating the number and function of CD8+ T cells. [ABSTRACT FROM AUTHOR]

Published
2024
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17. Poly(3,4-ethylenedioxythiophene)-Coated Vanadium-Doped MnO2Nanorods for High-Performance Flexible Aqueous Zinc-Ion Battery Cathode

Author

Sun, Yuning, Huang, Changjun, Liu, Yuexin, Zhao, Xiaoli, and Cai, Kefeng

Abstract

Manganese-based aqueous zinc-ion batteries (AZIBs) are considered promising cathode materials for large-scale energy storage applications due to their low cost and high safety. However, the primary constraints on achieving high specific capacity and cycling stability are the inherent low conductivity and suboptimal structural stability of the AZIB cathodes. Herein, we report a high-performance poly(3,4-ethylenedioxythiophene) (PEDOT)-coated vanadium-doped MnO2nanorod (NR) electrode for AZIBs. First, vanadium-doped MnO2(V-MnO2) NRs were synthesized by a simple hydrothermal synthesis method. The V-MnO2NRs were further encapsulated with a nanolayer of PEDOT through an in situpolymerization process, which was subsequently treated with sulfuric acid to achieve a smooth surface. The V doping creates oxygen vacancies within the MnO2, allowing for the rapid embedding and diffusion of Zn2+. The PEDOT nanolayer greatly enhances the conductivity and structural stability of the V-MnO2. Benefiting from the unique features, an optimal composite NRs electrode exhibits a high specific capacity of 250 mAh g–1at 0.4 A g–1, a high energy density (388 Wh kg–1at 151 W kg–1), and excellent stability over 5000 cycles at 3 A g–1. In addition, the flexible pouch cell assembled with the electrode shows good stability under bending. Given the positive outcomes, the material holds great potential for use as a cathode in next-generation flexible energy storage systems.

Published
2024
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18. Greatly Enhanced Thermoelectric Performance of Flexible Cu 2−x S Composite Film on Nylon by Se Doping.

Author

Zuo, Xinru, Han, Xiaowen, Wang, Zixing, Liu, Ying, Li, Jiajia, Zhang, Mingcheng, Huang, Changjun, and Cai, Kefeng

Subjects
CARRIER density, NYLON, HYDROTHERMAL synthesis, HOT pressing, POWER density
Abstract

In this work, flexible Cu2−xS films on nylon membranes are prepared by combining a simple hydrothermal synthesis and vacuum filtration followed by hot pressing. The films consist of Cu2S and Cu1.96S two phases with grain sizes from nano to submicron. Doping Se on the S site not only increases the Cu1.96S content in the Cu2−xS to increase carrier concentration but also modifies electronic structure, thereby greatly improves the electrical properties of the Cu2−xS. Specifically, an optimal composite film with a nominal composition of Cu2−xS0.98Se0.02 exhibits a high power factor of ~150.1 μW m−1 K−2 at 300 K, which increases by ~138% compared to that of the pristine Cu2−xS film. Meanwhile, the composite film shows outstanding flexibility (~97.2% of the original electrical conductivity is maintained after 1500 bending cycles with a bending radius of 4 mm). A four-leg flexible thermoelectric (TE) generator assembled with the optimal film generates a maximum power of 329.6 nW (corresponding power density of 1.70 W m−2) at a temperature difference of 31.1 K. This work provides a simple route to the preparation of high TE performance Cu2−xS-based films. [ABSTRACT FROM AUTHOR]

Published
2024
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21. Effect of Ursodeoxycholic Acid on Preventing SARS-CoV-2 Infection in Patients With Liver Transplantation: a multicenter retrospective cohort study

Author

Hu, Liangshuo, primary, Zhang, Huapeng, additional, Huang, Changjun, additional, Shen, Tianli, additional, Feng, Zhaozu, additional, Mu, Fan, additional, Xu, Lexuan, additional, Lin, Yuyao, additional, Yue, Chenyang, additional, Guo, Kun, additional, Tian, Min, additional, Shi, Jianhua, additional, Zhang, Chun, additional, Wen, Peihao, additional, Cao, Shengli, additional, Wang, Yun, additional, Zhang, Jiakai, additional, Shi, Xiaoyi, additional, Wang, Zhihui, additional, He, Yuting, additional, Zhang, Xiaogang, additional, Liu, Xuemin, additional, Lv, Yi, additional, Liu, Zhengwen, additional, Guo, Wenzhi, additional, and Wang, Bo, additional

Published
2023
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26. CRISPR/Cas9‐mediated seamless gene replacement in protoplasts expands the resistance spectrum to TMV‐U1 strain in regenerated Nicotiana tabacum

Author

Li, Yanli, primary, Huang, Changjun, additional, Liu, Yong, additional, Zeng, Jianmin, additional, Yu, Haiqin, additional, Tong, Zhijun, additional, Yuan, Xinjie, additional, Sui, Xueyi, additional, Fang, Dunhuang, additional, Xiao, Bingguang, additional, Zhao, Shancen, additional, and Yuan, Cheng, additional

Published
2023
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29. Interspecies/Intergroup Complementation of Orthotospovirus Replication and Movement through Reverse Genetics Systems

Author

Feng, Mingfeng, primary, Chen, Minglong, additional, Yuan, Yulong, additional, Liu, Qinhai, additional, Cheng, Ruixiang, additional, Yang, Tongqing, additional, Li, Luyao, additional, Guo, Rong, additional, Dong, Yongxin, additional, Chen, Jing, additional, Yang, Yawen, additional, Yan, Yuling, additional, Cui, Hongmin, additional, Jing, Dong, additional, Kang, Jinrui, additional, Chen, Shuxian, additional, Li, Jia, additional, Zhu, Min, additional, Huang, Changjun, additional, Zhang, Zhongkai, additional, Kormelink, Richard, additional, and Tao, Xiaorong, additional

Published
2023
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32. Interspecies/Intergroup Complementation of Orthotospovirus Replication and Movement through Reverse Genetics Systems

Author

Feng, Mingfeng, Chen, Minglong, Yuan, Yulong, Liu, Qinhai, Cheng, Ruixiang, Yang, Tongqing, Li, Luyao, Guo, Rong, Dong, Yongxin, Chen, Jing, Yang, Yawen, Yan, Yuling, Cui, Hongmin, Jing, Dong, Kang, Jinrui, Chen, Shuxian, Li, Jia, Zhu, Min, Huang, Changjun, Zhang, Zhongkai, Kormelink, Richard, Tao, Xiaorong, Feng, Mingfeng, Chen, Minglong, Yuan, Yulong, Liu, Qinhai, Cheng, Ruixiang, Yang, Tongqing, Li, Luyao, Guo, Rong, Dong, Yongxin, Chen, Jing, Yang, Yawen, Yan, Yuling, Cui, Hongmin, Jing, Dong, Kang, Jinrui, Chen, Shuxian, Li, Jia, Zhu, Min, Huang, Changjun, Zhang, Zhongkai, Kormelink, Richard, and Tao, Xiaorong

Abstract

Orthotospoviruses, the plant-infecting bunyaviruses, cause serious diseases in agronomic crops and pose major threats to global food security. The family of Tospoviridae contains more than 30 members that are classified into two geographic groups, American-type and Euro/Asian-type orthotospovirus. However, the genetic interaction between different species and the possibility, during mixed infections, for transcomplementation of gene functions by orthotospoviruses from different geographic groups remains underexplored. In this study, minireplicon-based reverse genetics (RG) systems have been established for Impatiens necrotic spot virus (INSV) (an American-type orthotospovirus) and for Calla lily chlorotic spot virus and Tomato zonate spot virus (CCSV and TZSV) (two representative Euro/Asian orthotospoviruses). Together with the earlier established RG system for Tomato spotted wilt virus (TSWV), a type species of the Orthotospovirus American-clade, viral replicase/movement proteins were exchanged and analyzed on interspecies transcomplementation. Whereas the homologous RNA-dependent RNA polymerase (RdRp) and nucleocapsid (N) protein supported the replication of orthotospoviruses from both geographic groups, heterologous combinations of RdRp from one group and N from the other group were unable to support the replication of viruses from both groups. Furthermore, the NSm movement protein (MP), from both geographic groups of orthotospoviruses, was able to transcomplement heterologous orthotospoviruses or a positive-strand Cucumber mosaic virus (CMV) in their movement, albeit with varying efficiency. MP from Rice stripe tenuivirus (RSV), a plant-infecting bunyavirus that is distinct from orthotospoviruses, or MP from CMV also moves orthotospoviruses. Our findings gain insights into the genetic interaction/reassortant potentials for the segmented plant orthotospoviruses. IMPORTANCE Orthotospoviruses are agriculturally important negative-strand RNA viruses and cause severe

Published
2023

34. High-Performance Ag 2 Se Film by a Microwave-Assisted Synthesis Method for Flexible Thermoelectric Generators.

Author

Wang, Zixing, Liu, Ying, Li, Jiajia, Huang, Changjun, and Cai, Kefeng

Subjects
THERMOELECTRIC generators, HOT pressing, POWER density, NANOWIRES, POWDERS
Abstract

Flexible Ag2Se thermoelectric (TE) films are promising for wearable applications near room temperature (RT). Herein, a Ag2Se film on a nylon membrane with high TE performance was fabricated by a facile method. First, Ag2Se powders were prepared by a microwave-assisted synthesis method using Ag nanowires as a template. Second, the Ag2Se powders were deposited onto nylon via vacuum filtration followed by hot pressing. Through modulating the Ag/Se molar ratio for synthesizing the Ag2Se powders, an optimized Ag2Se film demonstrates a high power factor of 1577.1 μW m−1 K−2 and good flexibility at RT. The flexibility of the Ag2Se film is mainly attributed to the flexible nylon membrane. In addition, a six-leg flexible TE generator (f-TEG) fabricated with the optimized Ag2Se film exhibits a maximum power density of 18.4 W m−2 at a temperature difference of 29 K near RT. This work provides a new solution to prepare high-TE-performance flexible Ag2Se films for f-TEGs. [ABSTRACT FROM AUTHOR]

Published
2023
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37. Abrogation of graft ischemia‐reperfusion injury in ischemia‐free liver transplantation

Author

Guo, Zhiyong, primary, Xu, Jinghong, additional, Huang, Shanzhou, additional, Yin, Meixian, additional, Zhao, Qiang, additional, Ju, Weiqiang, additional, Wang, Dongping, additional, Gao, Ningxin, additional, Huang, Changjun, additional, Yang, Lu, additional, Chen, Maogen, additional, Zhang, Zhiheng, additional, Zhu, Zebin, additional, Wang, Linhe, additional, Zhu, Caihui, additional, Zhang, Yixi, additional, Tang, Yunhua, additional, Chen, Haitian, additional, Liu, Kunpeng, additional, Lu, Yuting, additional, Ma, Yi, additional, Hu, Anbin, additional, Chen, Yinghua, additional, Zhu, Xiaofeng, additional, and He, Xiaoshun, additional

Published
2022
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38. Construction and characterization of a BAC library for flue-cured tobacco line with high resistance to blank shank

Author

Cheng Yuan, Hai-Qin Yu, Xue Yang, Liu Yong, Zhi-Jun Tong, Mei-Zhong Luo, De-Qing Ma, Fang Dunhuang, Qing-Yuan Dong, Huang Changjun, Yong-Ping Li, Yin-Lian Xu, Jun-Ru Shen, and Zeng Jianmin

Subjects
Genetics, Bacterial artificial chromosome, genomic DNA, Curing of tobacco, Plant Science, Quantitative trait locus, Biology, Agronomy and Crop Science, Genome size, Gene, Genome, Insert (molecular biology), Biotechnology
Abstract

Tobacco ( N. tabacum ) is an important model crop in molecular biology research. In this study, a bacterial artificial chromosome (BAC) library of a flue-cured tobacco line 14–60 with high blank shank resistance and good quality was constructed. High molecular weight DNA was isolated using intact nuclei from tobacco, partially cleaved with Hin d III and cloned into the pIndigoBAC536-S vector. The BAC library consisted of 414,720 clones arrayed in one thousand and eighty 384-microtite plates, with an average insert size of 123 kb ranging from 97.0–145.5 kb. No empty insert clone was found. Based on an estimated genome size of 4500 Mb for common tobacco, the BAC library was estimated to cover 11 times of genome equivalents. The utility of the library was further confirmed by screening the library with the primers of tobacco hem A, NtFT , and eIF4E- 1 genes. The high capacity library will serve as a giant genomic resource for map-based cloning of quantitative trait loci or genes associated with important agronomic and smoking quality traits or resistance to blank shank, physical mapping and comparative genome analysis.

Published
2020

41. Ischaemia-free liver transplantation in humans: a first-in-human trial

Author

Guo, Zhiyong, primary, Zhao, Qiang, additional, Huang, Shanzhou, additional, Huang, Changjun, additional, Wang, Dongping, additional, Yang, Lu, additional, Zhang, Jian, additional, Chen, Maogen, additional, Wu, Linwei, additional, Zhang, Zhiheng, additional, Zhu, Zebin, additional, Wang, Linhe, additional, Zhu, Caihui, additional, Zhang, Yixi, additional, Tang, Yunhua, additional, Sun, Chengjun, additional, Xiong, Wei, additional, Shen, Yuekun, additional, Chen, Xiaoxiang, additional, Xu, Jinghong, additional, Wang, Tielong, additional, Ma, Yi, additional, Hu, Anbin, additional, Chen, Yinghua, additional, Zhu, Xiaofeng, additional, Rong, Jian, additional, Cai, Changjie, additional, Gong, Fengqiu, additional, Guan, Xiangdong, additional, Huang, Wenqi, additional, Ko, Dicken Shiu-Chung, additional, Li, Xianchang, additional, Tullius, Stefan G, additional, Huang, Jiefu, additional, Ju, Weiqiang, additional, and He, Xiaoshun, additional

Published
2021
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42. Two TOBAMOVIRUS MULTIPLICATION 2A homologs in tobacco control asymptomatic response to tobacco mosaic virus

Author

Kunpeng Li, Qun Hu, Zefan Chen, Lei Zhang, Hui Zhang, Huang Changjun, Hanhui Kuang, Yong Liu, Robert M. Larkin, Cheng Yuan, and Jiongjiong Chen

Subjects
Genetics, Regular Issue, biology, Physiology, Host (biology), viruses, Nicotiana tabacum, fungi, Arabidopsis, food and beverages, Tobamovirus, Plant Science, biology.organism_classification, Virus Replication, Tobacco Mosaic Virus, Tobacco, Tobacco mosaic virus, Tomato mosaic virus, Gene, Nicotiana, Plant Diseases, Plant Proteins
Abstract

The most common response of a host to pathogens is arguably the asymptomatic response. However, the genetic and molecular mechanisms responsible for asymptomatic responses to pathogens are poorly understood. Here we report on the genetic cloning of two genes controlling the asymptomatic response to tobacco mosaic virus (TMV) in cultivated tobacco (Nicotiana tabacum). These two genes are homologous to tobamovirus multiplication 2A (TOM2A) from Arabidopsis, which was shown to be critical for the accumulation of TMV. Expression analysis indicates that the TOM2A genes might play fundamental roles in plant development or in responses to stresses. Consistent with this hypothesis, a null allele of the TOM2A ortholog in tomato (Solanum lycopersicum) led to the development of bent branches and a high tolerance to both TMV and tomato mosaic virus (ToMV). However, the TOM2A ortholog in Nicotiana glauca did not account for the asymptomatic response to TMV in N. glauca. We showed that TOM2A family is plant-specific and originated from Chlorophyte, and the biological functions of TOM2A orthologs to promote TMV accumulation are highly conserved in the plant kingdom—in both TMV host and nonhost species. In addition, we showed that the interaction between tobacco TOM1 and TOM2A orthologs in plant species is conserved, suggesting a conserved nature of TOM1–TOM2A module in promoting TMV multiplication in plants. The tradeoff between host development, the resistance of hosts to pathogens, and their influence on gene evolution are discussed. Our results shed light on mechanisms that contribute to asymptomatic responses to viruses in plants and provide approaches for developing TMV/ToMV-resistant crops.

Published
2021

46. DTYMK Expression Predicts Prognosis and Chemotherapeutic Response and Correlates with Immune Infiltration in Hepatocellular Carcinoma

Author

Guo, Yiwen, primary, Luo, Weixin, additional, Huang, Shanzhou, additional, Zhao, Wenting, additional, Chen, Huadi, additional, Ma, Yihao, additional, Ye, Maodong, additional, Nie, Yu, additional, Zhang, Yixi, additional, Huang, Changjun, additional, Zhou, Qi, additional, He, Xiaoshun, additional, and Chen, Maogen, additional

Published
2021
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48. Transcriptomic analysis provides insights into the AUXIN RESPONSE FACTOR 6-mediated repression of nicotine biosynthesis in tobacco (Nicotiana tabacum L.)

Author

Sui Xueyi, Yulong Gao, Longchang Wang, Zou Congming, Zhao Lu, Zhang Hongbo, Hu Mengyang, Yihan Zhang, Yuan Cheng, Huang Changjun, Zhongbang Song, and Bingwu Wang

Subjects
Nicotine, Nicotiana tabacum, Repressor, Plant Science, Saccharomyces cerevisiae, chemistry.chemical_compound, Alkaloids, Gene Expression Regulation, Plant, Plant Cells, Genes, Regulator, Tobacco, Genetics, medicine, Cluster Analysis, Amino Acid Sequence, Promoter Regions, Genetic, Psychological repression, Transcription factor, Phylogeny, Plant Proteins, biology, Jasmonic acid, Gene Expression Profiling, General Medicine, biology.organism_classification, Plants, Genetically Modified, Cell biology, Biosynthetic Pathways, Metabolic pathway, Gene Ontology, chemistry, Organ Specificity, Plant hormone, Transcriptome, Agronomy and Crop Science, Genome, Plant, medicine.drug, Protein Binding, Subcellular Fractions
Abstract

NtARF6 overexpression represses nicotine biosynthesis in tobacco. Transcriptome analysis suggests that NtARF6 acts as a regulatory hub that connect different phytohormone signaling pathways to antagonize the jasmonic acid-induced nicotine biosynthesis. Plant specialized metabolic pathways are regulated by a plethora of molecular regulators that form complex networks. In Nicotiana tabacum, nicotine biosynthesis is regulated by transcriptional activators, such as NtMYC2 and the NIC2-locus ERFs. However, the underlying molecular mechanism of the regulatory feedback is largely unknown. Previous research has shown that NbARF1, a nicotine synthesis repressor, reduces nicotine accumulation in N. benthamiana. In this study, we demonstrated that overexpression of NtARF6, an ortholog of NbARF1, was able to reduce pyridine alkaloid accumulation in tobacco. We found that NtARF6 could not directly repress the transcriptional activities of the key nicotine pathway structural gene promoters. Transcriptomic analysis suggested that this NtARF6-induced deactivation of alkaloid biosynthesis might be achieved by the antagonistic effect between jasmonic acid (JA) and other plant hormone signaling pathways, such as ethylene (ETH), salicylic acid (SA), abscisic acid (ABA). The repression of JA biosynthesis is accompanied by the induction of ETH, ABA, and SA signaling and pathogenic infection defensive responses, resulting in counteracting JA-induced metabolic reprogramming and decreasing the expression of nicotine biosynthetic genes in vivo. This study provides transcriptomic evidence for the regulatory mechanism of the NtARF6-mediated repression of alkaloid biosynthesis and indicates that this ARF transcription factor might act as a regulatory hub to connect different hormone signaling pathways in tobacco.

Published
2021

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