Search

Positron emission tomography (PET) is an advanced medical imaging technique that plays a crucial role in non-invasive clinical diagnosis. However, while reducing radiation exposure through low-dose PET scans is beneficial for patient safety, it often results in insufficient statistical data. This scarcity of data poses significant challenges for accurately reconstructing high-quality images, which are essential for reliable diagnostic outcomes. In this research, we propose a diffusion transformer model (DTM) guided by joint compact prior (JCP) to enhance the reconstruction quality of low-dose PET imaging. In light of current research findings, we present a pioneering PET reconstruction model that integrates diffusion and transformer models for joint optimization. This model combines the powerful distribution mapping abilities of diffusion models with the capacity of transformers to capture long-range dependencies, offering significant advantages for low-dose PET reconstruction. Additionally, the incorporation of the lesion refining block and penalized weighted least squares (PWLS) enhance the recovery capability of lesion regions and preserves detail information, solving blurring problems in lesion areas and texture details of most deep learning frameworks. Experimental results demonstrate the effectiveness of DTM in enhancing image quality and preserving critical clinical information for low-dose PET scans. Our approach not only reduces radiation exposure risks but also provides a more reliable PET imaging tool for early disease detection and patient management.

Marine fog poses a significant hazard to global shipping, necessitating effective detection and forecasting to reduce economic losses. In recent years, several machine learning (ML) methods have demonstrated superior detection accuracy compared to traditional meteorological methods. However, most of these works are developed on proprietary datasets, and the few publicly accessible datasets are often limited to simplistic toy scenarios for research purposes. To advance the field, we have collected nearly a decade's worth of multi-modal data related to continuous marine fog stages from four series of geostationary meteorological satellites, along with meteorological observations and numerical analysis, covering 15 marine regions globally where maritime fog frequently occurs. Through pixel-level manual annotation by meteorological experts, we present the most comprehensive marine fog detection and forecasting dataset to date, named M4Fog, to bridge ocean and atmosphere. The dataset comprises 68,000 "super data cubes" along four dimensions: elements, latitude, longitude and time, with a temporal resolution of half an hour and a spatial resolution of 1 kilometer. Considering practical applications, we have defined and explored three meaningful tracks with multi-metric evaluation systems: static or dynamic marine fog detection, and spatio-temporal forecasting for cloud images. Extensive benchmarking and experiments demonstrate the rationality and effectiveness of the construction concept for proposed M4Fog. The data and codes are available to whole researchers through cloud platforms to develop ML-driven marine fog solutions and mitigate adverse impacts on human activities.

Low-dose computed tomography (LDCT) plays a vital role in clinical applications by mitigating radiation risks. Nevertheless, reducing radiation doses significantly degrades image quality. Concurrently, common deep learning methods demand extensive data, posing concerns about privacy, cost, and time constraints. Consequently, we propose a few-shot low-dose CT reconstruction method using Partitioned Hankel-based Diffusion (PHD) models. During the prior learning stage, the projection data is first transformed into multiple partitioned Hankel matrices. Structured tensors are then extracted from these matrices to facilitate prior learning through multiple diffusion models. In the iterative reconstruction stage, an iterative stochastic differential equation solver is employed along with data consistency constraints to update the acquired projection data. Furthermore, penalized weighted least-squares and total variation techniques are introduced to enhance the resulting image quality. The results approximate those of normal-dose counterparts, validating PHD model as an effective and practical model for reducing artifacts and noise while preserving image quality.

Computed Tomography (CT) technology reduces radiation haz-ards to the human body through sparse sampling, but fewer sampling angles pose challenges for image reconstruction. Score-based generative models are widely used in sparse-view CT re-construction, performance diminishes significantly with a sharp reduction in projection angles. Therefore, we propose an ultra-sparse view CT reconstruction method utilizing multi-scale dif-fusion models (MSDiff), designed to concentrate on the global distribution of information and facilitate the reconstruction of sparse views with local image characteristics. Specifically, the proposed model ingeniously integrates information from both comprehensive sampling and selectively sparse sampling tech-niques. Through precise adjustments in diffusion model, it is capable of extracting diverse noise distribution, furthering the understanding of the overall structure of images, and aiding the fully sampled model in recovering image information more effec-tively. By leveraging the inherent correlations within the projec-tion data, we have designed an equidistant mask, enabling the model to focus its attention more effectively. Experimental re-sults demonstrated that the multi-scale model approach signifi-cantly improved the quality of image reconstruction under ultra-sparse angles, with good generalization across various datasets.

Protein circular permutations are crucial for understanding protein evolution and functionality. Traditional detection methods, sequence-based or structure-based, struggle with accuracy and computational efficiency, the latter also limited by treating proteins as rigid bodies. The plmCP method, utilizing a protein language model, not only speeds up the detection process but also enhances the accuracy of identifying circular permutations, contributing significantly to protein research and engineering by acknowledging structural flexibility.

Good health and well-being is among key issues in the United Nations 2030 Sustainable Development Goals. The rising prevalence of large-scale infectious diseases and the accelerated aging of the global population are driving the transformation of healthcare technologies. In this context, establishing large-scale public health datasets, developing medical models, and creating decision-making systems with a human-centric approach are of strategic significance. Recently, by leveraging the extraordinary number of accessible cameras, groundbreaking advancements have emerged in AI methods for physiological signal monitoring and disease diagnosis using camera sensors. These approaches, requiring no specialized medical equipment, offer convenient manners of collecting large-scale medical data in response to public health events. Therefore, we outline a prospective framework and heuristic vision for a camera-based public health (CBPH) framework utilizing visual physiological monitoring technology. The CBPH can be considered as a convenient and universal framework for public health, advancing the United Nations Sustainable Development Goals, particularly in promoting the universality, sustainability, and equity of healthcare in low- and middle-income countries or regions. Furthermore, CBPH provides a comprehensive solution for building a large-scale and human-centric medical database, and a multi-task large medical model for public health and medical scientific discoveries. It has a significant potential to revolutionize personal monitoring technologies, digital medicine, telemedicine, and primary health care in public health. Therefore, it can be deemed that the outcomes of this paper will contribute to the establishment of a sustainable and fair framework for public health, which serves as a crucial bridge for advancing scientific discoveries in the realm of AI for medicine (AI4Medicine)., Comment: 16 pages, 5 figures

Multimodal large language models (MLLMs) are designed to process and integrate information from multiple sources, such as text, speech, images, and videos. Despite its success in language understanding, it is critical to evaluate the performance of downstream tasks for better human-centric applications. This paper assesses the application of MLLMs with 5 crucial abilities for affective computing, spanning from visual affective tasks and reasoning tasks. The results show that \gpt has high accuracy in facial action unit recognition and micro-expression detection while its general facial expression recognition performance is not accurate. We also highlight the challenges of achieving fine-grained micro-expression recognition and the potential for further study and demonstrate the versatility and potential of \gpt for handling advanced tasks in emotion recognition and related fields by integrating with task-related agents for more complex tasks, such as heart rate estimation through signal processing. In conclusion, this paper provides valuable insights into the potential applications and challenges of MLLMs in human-centric computing. Our interesting examples are at https://github.com/EnVision-Research/GPT4Affectivity.

In the realm of cryptocurrency, the prediction of Bitcoin prices has garnered substantial attention due to its potential impact on financial markets and investment strategies. This paper propose a comparative study on hybrid machine learning algorithms and leverage on enhancing model interpretability. Specifically, linear regression(OLS, LASSO), long-short term memory(LSTM), decision tree regressors are introduced. Through the grounded experiments, we observe linear regressor achieves the best performance among candidate models. For the interpretability, we carry out a systematic overview on the preprocessing techniques of time-series statistics, including decomposition, auto-correlational function, exponential triple forecasting, which aim to excavate latent relations and complex patterns appeared in the financial time-series forecasting. We believe this work may derive more attention and inspire more researches in the realm of time-series analysis and its realistic applications.

Diffusion models have emerged as potential tools to tackle the challenge of sparse-view CT reconstruction, displaying superior performance compared to conventional methods. Nevertheless, these prevailing diffusion models predominantly focus on the sinogram or image domains, which can lead to instability during model training, potentially culminating in convergence towards local minimal solutions. The wavelet trans-form serves to disentangle image contents and features into distinct frequency-component bands at varying scales, adeptly capturing diverse directional structures. Employing the Wavelet transform as a guiding sparsity prior significantly enhances the robustness of diffusion models. In this study, we present an innovative approach named the Stage-by-stage Wavelet Optimization Refinement Diffusion (SWORD) model for sparse-view CT reconstruction. Specifically, we establish a unified mathematical model integrating low-frequency and high-frequency generative models, achieving the solution with optimization procedure. Furthermore, we perform the low-frequency and high-frequency generative models on wavelet's decomposed components rather than sinogram or image domains, ensuring the stability of model training. Our method rooted in established optimization theory, comprising three distinct stages, including low-frequency generation, high-frequency refinement and domain transform. Our experimental results demonstrate that the proposed method outperforms existing state-of-the-art methods both quantitatively and qualitatively.

This paper shows that Masking the Deep hierarchical features is an efficient self-supervised method, denoted as MaskDeep. MaskDeep treats each patch in the representation space as an independent instance. We mask part of patches in the representation space and then utilize sparse visible patches to reconstruct high semantic image representation. The intuition of MaskDeep lies in the fact that models can reason from sparse visible patches semantic to the global semantic of the image. We further propose three designs in our framework: 1) a Hierarchical Deep-Masking module to concern the hierarchical property of patch representations, 2) a multi-group strategy to improve the efficiency without any extra computing consumption of the encoder and 3) a multi-target strategy to provide more description of the global semantic. Our MaskDeep brings decent improvements. Trained on ResNet50 with 200 epochs, MaskDeep achieves state-of-the-art results of 71.2% Top1 accuracy linear classification on ImageNet. On COCO object detection tasks, MaskDeep outperforms the self-supervised method SoCo, which specifically designed for object detection. When trained with 100 epochs, MaskDeep achieves 69.6% Top1 accuracy, which surpasses current methods trained with 200 epochs, such as HCSC, by 0.4% .