18 results on '"Huai Yuan Wang"'
Search Results
2. Prognostic analysis of patients with combined hepatocellular-cholangiocarcinoma after radical resection: A retrospective multicenter cohort study
- Author
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Ge Zhang, Bo-Wen Chen, Xiao-Bo Yang, Huai-Yuan Wang, Xu Yang, Fu-Cun Xie, Xiang-Qi Chen, Ling-Xiang Yu, Jie Shi, Yin-Ying Lu, and Hai-Tao Zhao
- Subjects
Male ,Carcinoma, Hepatocellular ,CA-19-9 Antigen ,Liver Neoplasms ,Gastroenterology ,General Medicine ,Prognosis ,Cohort Studies ,Cholangiocarcinoma ,Bile Ducts, Intrahepatic ,Bile Duct Neoplasms ,Humans ,Multicenter Studies as Topic ,Female ,Chemoembolization, Therapeutic ,Neoplasm Recurrence, Local ,Retrospective Studies - Abstract
Combined hepatocellular-cholangiocarcinoma (cHCC-CCA) is a form of rare primary liver cancer that combines intrahepatic cholangiocarcinoma (ICC) and hepatocellular carcinoma.To investigate overall survival (OS) and recurrence-free survival (RFS) after radical resection in patients with cHCC-CCA, and the clinicopathological factors affecting prognosis in two center hospitals of China.We reviewed consecutive patients with cHCC-CCA who received radical resection between January 2005 and September 2021 at Peking Union Medical College and the 5th Medical Center of the PLA General Hospital retrospectively. Regular follow-up and clinicopathological characteristics were systematic collected for baseline and prognostic analysis.Our study included 95 patients who received radical resection. The majority of these patients were male and 82.7% of these patients were infected with HBV. The mean tumor size was 4.5 cm, and approximately 40% of patients had more than one lesion. The median OS was 26.8 (95%CI: 18.5-43.0) mo, and the median RFS was 7.27 (95%CI: 5.83-10.3) mo. Independent predictors of OS were CA19-9 ≥ 37 U/mL (HR = 8.68,The overall postoperative survival of cHCC-CCA patients is poor, and most patients experience relapse within a short period of time after surgery. Preoperative tumor biomarker (CA19-9, alpha-fetoprotein) levels, tumor size, and Child-Pugh score can significantly affect OS. Adjuvant TACE after surgery prolongs RFS, suggesting that TACE is a possible option for postoperative adjuvant therapy in patients with cHCC-CCA.
- Published
- 2022
3. Enhanced anti-melanoma efficacy through a combination of the armed oncolytic adenovirus ZD55-IL-24 and immune checkpoint blockade in B16-bearing immunocompetent mouse model
- Author
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Xiu Liang, Jing Xiao, Jinfa Gu, Ai-Min Ni, Hai-Jun Hu, Hai-Lang Li, Lanying Sun, Jin-Qing Hu, Xinyuan Liu, and Huai-Yuan Wang
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Oncolytic adenovirus ,Cancer Research ,Oncolytic virus ,Combination therapy ,Tumor immune recognition ,medicine.medical_treatment ,Immunology ,PD-1 blockade ,Adenoviridae ,Cell Line ,Mice ,03 medical and health sciences ,0302 clinical medicine ,Cell Line, Tumor ,medicine ,Animals ,Humans ,Immunology and Allergy ,Melanoma ,Immune Checkpoint Inhibitors ,030304 developmental biology ,Oncolytic Virotherapy ,0303 health sciences ,business.industry ,Interleukins ,Therapeutic effect ,Genetic Therapy ,Immunotherapy ,medicine.disease ,Combined Modality Therapy ,Immune checkpoint ,Blockade ,Mice, Inbred C57BL ,Disease Models, Animal ,Oncolytic Viruses ,HEK293 Cells ,Oncology ,030220 oncology & carcinogenesis ,Cancer research ,Original Article ,Female ,business ,Tumor immune infiltration - Abstract
Although the recent treatment in melanoma through the use of anti-PD-1 immunotherapy is successful, the efficacy of this approach remains to be improved. Here, we explore the feasibility of combination strategy with the armed oncolytic adenovirus ZD55-IL-24 and PD-1 blockade. We find that combination therapy with localized ZD55-IL-24 and systemic PD-1 blockade leads to synergistic inhibition of both local and distant established tumors in B16-bearing immunocompetent mouse model. Our further mechanism investigation reveals that synergistic therapeutic effect is associated with marked promotion of tumor immune infiltration and recognition in both local and distant tumors as well as spleens. PD-1 blockade has no obvious effect on promotion of tumor immune infiltration and recognition. Localized therapy with ZD55-IL-24, however, can help PD-1 blockade to overcome the limitation of relatively low tumor immune infiltration and recognition. This study provides a rationale for investigation of such combination therapy in the clinic. Supplementary information The online version contains supplementary material available at 10.1007/s00262-021-02946-z.
- Published
- 2021
4. Optimization of the Administration Strategy for the Armed Oncolytic Adenovirus ZD55-IL-24 in Both Immunocompromised and Immunocompetent Mouse Models
- Author
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Jing Xiao, Lanying Sun, Ai-Min Ni, Xiu Liang, Jinfa Gu, Jin-Qing Hu, Hai-Jun Hu, Hai-Lang Li, Xinyuan Liu, and Huai-Yuan Wang
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Oncolytic adenovirus ,Oncolytic Virotherapy ,0303 health sciences ,business.industry ,Cancer ,Mice, Nude ,Apoptosis ,medicine.disease ,Xenograft Model Antitumor Assays ,Adenoviridae ,03 medical and health sciences ,Disease Models, Animal ,Mice ,0302 clinical medicine ,030220 oncology & carcinogenesis ,Cell Line, Tumor ,Genetics ,medicine ,Cancer research ,Molecular Medicine ,Animals ,business ,Molecular Biology ,030304 developmental biology ,Immunocompetent mouse - Abstract
ZD55-IL-24 is an armed oncolytic adenovirus similar but superior to ONYX-015. Virotherapeutic strategies using ZD55-IL-24 have been demonstrated to be effective against several cancer types. However, it is unclear whether the traditional administration strategy is able to exert the maximal antitumor efficacy of ZD55-IL-24. In this study, we sought to optimize the administration strategy of ZD55-IL-24 in both A375-bearing immunocompromised mouse model and B16-bearing immunocompetent mouse model. Although the underlying antitumor mechanisms are quite different, the obtained results are similar in these two mouse tumor models. We find that the antitumor efficacy of ZD55-IL-24 increases as injection times increase in both of these two models. However, no obvious increase of efficacy is observed as the dose of each injection increases. Our further investigation reveals that the administration strategy of sustained ZD55-IL-24 therapy can achieve a better therapeutic effect than the traditional administration strategy of short-term ZD55-IL-24 therapy. Furthermore, there is no need to inject every day; every 2 or 3 days of injection achieves an equivalent therapeutic efficacy. Finally, we find that the sustained rather than the traditional short-term ZD55-IL-24 therapy can synergize with anti-PD-1 therapy to reject tumors in B16-bearing immunocompetent mouse model. These findings suggest that the past administration strategy of ZD55-IL-24 is in fact suboptimal and the antitumor efficacy can be further enhanced through administration strategy optimization. This study might shed some light on the development of clinically applicable administration regimens for ZD55-IL-24 therapy.
- Published
- 2021
5. Trail armed oncolytic poxvirus suppresses lung cancer cell by inducing apoptosis
- Author
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Jinfa Gu, Xiumei Zhou, Xinyuan Liu, Jinqing Hu, and Huai-Yuan Wang
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0301 basic medicine ,Lung Neoplasms ,Biophysics ,Mice, Nude ,Apoptosis ,Biochemistry ,TNF-Related Apoptosis-Inducing Ligand ,03 medical and health sciences ,Carcinoma, Lewis Lung ,0302 clinical medicine ,Cell Line, Tumor ,Medicine ,Animals ,Humans ,Lung cancer ,A549 cell ,Oncolytic Virotherapy ,business.industry ,Poxviridae ,General Medicine ,Genetic Therapy ,Hep G2 Cells ,medicine.disease ,HCT116 Cells ,Xenograft Model Antitumor Assays ,Oncolytic virus ,Mice, Inbred C57BL ,Oncolytic Viruses ,030104 developmental biology ,Cell culture ,A549 Cells ,030220 oncology & carcinogenesis ,Cancer cell ,Cancer research ,MCF-7 Cells ,Oncolytic Virus Therapy ,Tumor necrosis factor alpha ,Female ,business ,HeLa Cells - Abstract
Lung cancer has a high morbidity rate worldwide and is often resistant to therapy. Oncolytic virus therapy is a developing trend for cancer treatment. Thus, we constructed an oncolytic poxvirus carrying human trail gene that expresses a membrane-binding tumor necrosis factor and associated apoptosis-inducing ligand (TRAIL, Oncopox-trail). We hypothesized that the expression of trail would increase the efficacy of the oncolytic poxvirus. The effect of the TRAIL protein depends on the death receptors on the surface of different cancer cells. The expression of death receptors in lung cancer cell lines was analyzed by western blot analysis. In vitro, the oncolytic poxvirus carrying the trail gene displayed a better cytotoxicity at the cell level in the lung cancer cell line than that carrying the Oncopox-empty. TRAIL protein mainly induced apoptosis and inhibited necrosis. In vivo, two transplanted tumor models of human A549 lung cancer cells and mouse Lewis lung cancer cells were used to verify the anti-cancer effect of the oncolytic poxvirus carrying the trail gene. TUNEL staining results of the tumor histological sections also verified the anti-cancer effect. Similarly, through systemic administration of Oncopox-trail, the oncolytic poxvirus also exhibited anti-cancer effect.
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- 2018
6. Effect of the Reduction Temperature on Nickel Phosphide Catalyst Structure and Catalytic Activity for Hydrodesulfurization
- Author
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Zai Shun Jin, Fu Yong Zhang, Hua Song, Hua Lin Song, Yan Ji Zhu, and Huai Yuan Wang
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Thermogravimetry ,chemistry.chemical_compound ,Nickel ,chemistry ,Phosphide ,Specific surface area ,Differential thermal analysis ,Inorganic chemistry ,General Engineering ,chemistry.chemical_element ,Hydrodesulfurization ,Catalysis ,Space velocity - Abstract
Ni2P/TiO2-Al2O3catalysts were prepared by impregnation of nickel phosphate precursors followed by reduction in hydrogen. The catalysts were characterized by X-ray diffraction (XRD), N2-adsorption specific surface area measurements (BET), transmission electron microscope (TEM), X-ray photoelectron spectroscopy (XPS) and thermogravimetry differential thermal analysis (TG-DTA). The effects of reduction temperature on catalyst structure and HDS activity were studied using a lab-scale continuous flow fixed-bed reactor.. The results indicated that the catalyst prepared with reduction temperature of 973 K exhibited the best performance. At a reaction temperature of 606 K, a pressure of 3.0 MPa, a hydrogen/oil ratio of 500 (V/V), and a weight hourly space velocity (WHSV) of 2.0 h-1, the conversion of DBT HDS was 96.0%.
- Published
- 2014
7. Preparation of Nano Ni2P/TiO2-Al2O3 Catalyst and Catalytic Activity for Hydrodesulfurization
- Author
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Zai Shun Jin, Hua Lin Song, Feng Li, Huai Yuan Wang, Hua Song, and Zi Dong Wang
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Materials science ,Hydrogen ,Phosphide ,Inorganic chemistry ,General Engineering ,chemistry.chemical_element ,Catalysis ,chemistry.chemical_compound ,Reaction temperature ,chemistry ,X-ray photoelectron spectroscopy ,Nano ,Hydrodesulfurization ,Space velocity ,Nuclear chemistry - Abstract
nanonickel phosphide Ni2P catalysts supported on TiO2-Al2O3 support were prepared by impregnation. The catalysts were characterized by XRD, BET, and XPS. The effects of impregnation method,Ni2P loading on catalyst structure and HDS activity were studied. The results indicated that co-impregnation method is beneficial to the formation of Ni2P and can avoid the formation of Ni12P5. The catalyst prepared with co-impregnation method, Ni2P loading of 30% exhibited the best performance. At a reaction temperature of 606 K, a pressure of 3.0 MPa, a hydrogen/oil ratio of 500 (V/V), and a weight hourly space velocity (WHSV) of 2.0 h-1, the conversion of DBT HDS was 96.0%.
- Published
- 2014
8. Nanomechanical Properties of Core-Shell Structured Ni@NiO Nanoparticles Reinforced Epoxy Nanocomposites
- Author
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Lei Yan, Yan Ji Zhu, Huai Yuan Wang, Hua Song, and Jia Hua Zhu
- Subjects
Nanocomposite ,Materials science ,Polymer nanocomposite ,visual_art ,Non-blocking I/O ,General Engineering ,visual_art.visual_art_medium ,Nanoparticle ,Epoxy ,Wetting ,Nanoindentation ,Composite material ,Elastic modulus - Abstract
Epoxy resin (EP) nanocomposites reinforced with different contents of core-shell structured Ni@NiO nanoparticles (NPs) were fabricated by using a surface wetting method. The nanoindentation and nanoscratch properties of Ni@NiO/EP nanocomposites were comparatively studied based on nanoindentation technique. Results revealed that 5 wt.% content of Ni@NiO NPs was the optimal concentration for Ni@NiO/EP composites to obtain the best improvement of nanomechanical properties. In comparison with pristine EP, the highest enhancements of hardness and elastic modulus of 5 wt.% Ni@NiO/EP nanocomposites were increased by 37.8% and 16.3%, respectively.
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- 2014
9. Network Design in the Third Party Reverse Logistics of Swill Recycling
- Author
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Yuan Li and Huai Yuan Wang
- Subjects
Mainland China ,Network planning and design ,Third party ,General Engineering ,Business ,Reverse logistics ,Industrial organization - Abstract
Recent years, the failure of swill recycling in mainland China has led to severe problems. The lack of rational network is one of the most important factors. In this passage, a network design in the third party reverse logistics of swill recycling is developed and an example is discussed. The results show that the model is practical and useful.
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- 2013
10. Hydrothermal Preparation and Photocatalytic Activity of Different Morphology Titania
- Author
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You Zhuang Zhu, Yan Ji Zhu, Huai Yuan Wang, Zhen Yu, and Ying Chen
- Subjects
Anatase ,Materials science ,General Engineering ,Mineralogy ,Hydrothermal circulation ,Titanate ,chemistry.chemical_compound ,chemistry ,Chemical engineering ,Rutile ,Nanofiber ,Photocatalysis ,Methyl orange ,Mesoporous material - Abstract
TiO2 samples with various shapes like flake, nanofiber and large grain were synthesized by template-free hydrothermal method with rutile TiO2 or tetrabutyl titanate (Ti (OC4H9)4, TBOT) as precursor. Photocatalytic degradation performances were investigated by using methyl orange (MO) as modeling pollutant. The results shown that pure mesoporous anatase TiO2-Grain showed the highest photocatalytic activity (3.7 times higher than P25), which is due to a combinative effect of anatase phase and high specific surface areas. The bi-phase flaky TiO2 also have higher activity than P25. While, nanofiber with TiO2(B) phase has the lowest photocatalytic activity. The large sized TiO2 grain can be separated and recycled easily after reaction.
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- 2012
11. Tribological Behaviors of Polymer Based Composites under Alkaline Conditions
- Author
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Gui Ying Wang, Hui Juan Qian, Yan Ji Zhu, and Huai Yuan Wang
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chemistry.chemical_classification ,Polytetrafluoroethylene ,Materials science ,Scanning electron microscope ,Whiskers ,Abrasive ,Composite number ,General Engineering ,Polymer ,Tribology ,chemistry.chemical_compound ,chemistry ,Peek ,Composite material - Abstract
In this paper, polyetheretherketone (PEEK) and polytetrafluoroethylene (PTFE) based composites reinforced with various amounts of potassium titanate whiskers (PTWs) or short carbon fibers (CF) were designed and fabricated respectively. The friction and wear properties of PEEK and PTFE based composites sliding under rigorous alkaline were comparatively investigated. Also, the morphologies of the worn and counterpart surfaces were studied by scanning electron microscopy (SEM). Because of the stable tunnel crystal structure and frame structure micro-reinforcement capacity, PTWs show outstanding performances in increasing the wear resistance and reducing the friction coefficients of both PEEK and PTFE based composites under alkaline. However, CF leads to the degradation of wear resistance and the increase of friction coefficient of PEEK based composites under alkaline. Furrows and abrasive wear were the main mechanisms for CF/PTFE/PEEK and CF/PTFE composites sliding in alkali. The results show that PTW/PTFE composites exhibit higher wear resistance under lower load, while PTW/PTFE/PEEK composite is more suitable for higher load under alkaline condition. Owing to the primary cooling and boundary lubricating effects of alkali, the wear rates and friction coefficients of PTFE composites and PTW/PTFE/PEEK composites decreased obviously, though the transfer films onto the counterpart steel surface were hindered considerably.
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- 2012
12. The Asp Flooding Scaling Mechanism in Daqing Oilfield
- Author
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Huai Yuan Wang, Yongzhen Peng, Ji Xi Xu, Guo Lin Jing, and Shan Tang
- Subjects
Element analysis ,Materials science ,Scale (ratio) ,Petroleum engineering ,Scanning electron microscope ,General Engineering ,Formation water ,Deposition (phase transition) ,Scale deposition ,Scaling ,Flooding (computer networking) - Abstract
In the process of development in the oilfield, scale has been produced. Thus laboratory-scale deposition tests have been used to understand scale deposition mechanism. The process, mechanism and the main type of the scale in Asp flooding well of the forth plant of the Daqing oilfield were analyzed. To investigate the concentration change of the ions in the formation water with the injection of the Asp complex liquid and the scaling mechanism in the process of Asp flooding the core dissolution test was carried. Some of the scale samples were characterized by scanning electron microscope (SEM), and the results of the element analysis were investigated.
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- 2012
13. Friction and Wear Behaviors of Solid Lubricants/Polyimide Composites in Liquid Mediums
- Author
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Xin Feng, Yijun Shi, Liwen Mu, Huai Yuan Wang, and Xiaohua Lu
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chemistry.chemical_classification ,Work (thermodynamics) ,Materials science ,Mechanical Engineering ,Ionic bonding ,Polymer ,Tribology ,Condensed Matter Physics ,Alkali metal ,chemistry ,Mechanics of Materials ,General Materials Science ,Graphite ,Composite material ,Dry lubricant ,Polyimide - Abstract
The tribological properties of polyimide (PI) composites reinforced with graphite or MoS2 sliding in liquid alkali and water as well as dry friction were investigated using a ring-on-ring tester. The results show that the friction coefficient (μ) and wear rate (W) for both graphite/PI and MoS2/PI composites in different liquid mediums are μdry>μwater >μalkali and Wwater>Wdry >Walkali. Results also indicate that the friction coefficient and wear rate of the PI composites filled with different solid lubricants are μMoS2 >μgraphite and W MoS2 >Wgraphite in different liquid mediums. In addition, the hydrophobic inorganic fillers are fit for the reinforcement of polymer-based composites sliding in liquid mediums. It is also concluded from the authors’ work that the wear rate and friction coefficient of polymer-based (such as PI, PTFE) composites in the alkali lubricated conditions is lowest among all the friction conditions. This may be attributed to the ionic hydration in the alkaline solution.
- Published
- 2010
14. Tribological and Mechanical Properties of PTFE Composites Filled with the Combination of Short Carbon Fiber and Carbon Nanofiber
- Author
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Yijun Shi, Xin Feng, Huai Yuan Wang, and Xiaohua Lu
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Materials science ,Polytetrafluoroethylene ,Scanning electron microscope ,Carbon nanofiber ,Mechanical Engineering ,Composite number ,Nanoparticle ,Orders of magnitude (numbers) ,Tribology ,chemistry.chemical_compound ,chemistry ,Mechanics of Materials ,Ultimate tensile strength ,General Materials Science ,Composite material - Abstract
The tribological and mechanical properties of polytetrafluoroethylene (PTFE) composites filled with carbon nano-fiber (CNF), short carbon fiber (SCF) and the combination of them were studied. The results indicate that the wear volume loss of the PTFE composite filled with CNF or SCF, in comparison with that of pure PTFE, decreases by 1~2 orders of magnitude. And the best wear resistant composition is achieved by the combination of SCF with CNF; as an example, PTFE+2 wt% CNF+18 wt% SCF exhibits a specific wear volume loss of 0.88 mm3, which is about 11 times lower when compared to the PTFE composite filled with 18 wt% SCF. Meanwhile, the results also show that the tensile strength of SCF or CNF filled PTFE composites is better than that of pure PTFE. However, the combination of the two fillers decreases the tensile strength of PTFE composites. Worn surfaces were investigated using a scanning electron microscope, from which it is assumed that a mechanism of rolling effect, due to the filling of nanoparticles, which has a positive protective effect for PTFE matrix.
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- 2007
15. Tribological and Mechanical Properties of Carbon Nanofiber-Filled PTFE Composites
- Author
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Xiaohua Lu, X.S. Diao, Xin Feng, Yijun Shi, and Huai Yuan Wang
- Subjects
Filler (packaging) ,Polytetrafluoroethylene ,Materials science ,Scanning electron microscope ,Carbon nanofiber ,Composite number ,Tribology ,Condensed Matter Physics ,Atomic and Molecular Physics, and Optics ,chemistry.chemical_compound ,chemistry ,Ultimate tensile strength ,General Materials Science ,Composite material ,Elongation - Abstract
The tribological and mechanical properties of carbon nanofiber (CNF)-filled polytetrafluoroethylene (PTFE) composites with different filler proportions were studied. The worn surfaces of PTFE and carbon nanofiber/PTFE (CNF/PTFE) composites were then examined with scanning electron microscope (SEM). The results show the friction properties of CNF/PTFE composites decreased then increased with the increasing content of CNFs, while the anti-wear properties of CNF/PTFE composites were much higher than that of pure PTFE. The best anti-wear property was obtained with the composite containing 2 wt.% CNFs. The wear volume loss of the composite contained 2 wt.% CNFs was only about 1/700 that of PTFE without CNFs under the condition of 150N and 1.4m/s. Meanwhile, the results also indicate that the mechanical properties of CNF/PTFE composites increased then decreased with the increasing filler concentration, and the composite contained 1 wt.% CNFs has the best mechanical properties. Compare to pure PTFE, the tensile strength and the elongation of CNF/PTFE composites increased about 20% and 70% respectively when the filler content is 1 wt.%. It was seen from the worn surfaces micrographs of PTFE and CNF/PTFE composites that CNFs greatly reduce the adhesive wear of PTFE.
- Published
- 2007
16. [The immunogenicity and safety of 10 microg recombination yeast hepatitis B vaccine applied in expanded population]
- Author
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Qing-pei, Fu, Hui, He, Li, Li, Hai-ping, Chen, Yi-xue, Zeng, Qing-lian, Liu, Gang, Fang, Chun-ming, Dong, Shao-hong, Guo, Han-gang, Li, Huai-yuan, Wang, Chong-song, He, Shi-zhao, Zhou, Si-ning, Gu, Zheng-fang, Zhang, and Min, Dai
- Subjects
Male ,Vaccines, Synthetic ,Hepatitis B Surface Antigens ,Adolescent ,Child, Preschool ,Humans ,Female ,Hepatitis B Vaccines ,Hepatitis B Antibodies ,Child - Abstract
To assess the feasibility of the 10 microg recombination yeast hepatitis B vaccine in the expanded applicable population group aged 5 - 18.People with both HBsAg and anti-HBs negative were selected to take two-stage clinical experiment and the safety and immunogenicity were observed. Safety observation was conducted in 925 subjects, while 568 for immunogenicity. The observation group (aged 5 - 18) included 493 subjects, and (age18) 75 enrolled in control group. For the observation group, there were three sub-groups including a child group (141, aged 5 - 6), early youth group (177, aged 12 - 13), and youth group (175, aged 16 - 18). Both groups were administered with 10 microg recombination yeast hepatitis B vaccines with 3 doses at 0 month, 1st month, 6th month. To assess the immunogenicity, the vaccination reactions were observed during the following 4 weeks in order to assess the vaccine safety. The blood samples were taken during 4 - 6 weeks after fully vaccinated, and then anti-HBs were tested with RIA and analyzed by comparing the positive rate of anti-HBs, the geometric mean titer (GMT) and the protective rate between the two groups.Both observation and control group didn't show any general reactions, adverse events following immunization (AEFI) or coincidental cases when observed at 0.5 h, 6 h, 24 h, 48 h, 72 h, 1 week, 2 weeks, 3 weeks, 4 weeks after being vaccinated. The result of serum test showed, the positive rates of child group, early youth group, youth group and control group were respectively 100.00% (141/141), 97.18% (172/177), 98.29% (172/175) and 89.33% (67/75); the GMTs of anti-HBs were respectively 440.28, 875.38, 467.80, 131.06 U/L; the protective rates were respectively 100.00% (141/141), 97.18% (172/177), 97.14% (170/175) and 86.67% (65/75). The positive rate, GMT and protective rate of the experimental group were all higher than that of control group (chi(2)(positive rate) = 12.77, 5.12, 7.99; t(GMT) = 3.89, 4.13, 5.91; chi(2)(protective rate) = 16.81, 8.60, 8.44; P0.05).This vaccine could be expanded to 5 - 18 year-old population with safety and effectiveness, the positive rate and protective rate of anti-HBs were both higher than that of control group.
- Published
- 2010
17. Tribological and Mechanical Properties of PTFE Composites Filled with the Combination of Short Carbon Fiber and Carbon Nanofiber
- Author
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Yi Jun Shi, Xin Feng, Huai Yuan Wang, and Xiao Hua Lu
- Published
- 2007
18. Tribological and Mechanical Properties of Carbon Nanofiber-Filled PTFE Composites
- Author
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Yi Jun Shi, Xin Feng, X.S. Diao, Huai Yuan Wang, and Xiao Hua Lu
- Published
- 2007
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