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In this study, a novel multifunctional woven silk fabric characterized by quick-drying and bacteriostasis was developed through the addition of modified polyester filaments. The effect of fabric structure and filament proportion on the properties of multifunctional silk fabrics was investigated to determine the optimal weaving parameters for optimizing the overall fabric manufacturing process. Moreover, the fabric's basic wearing properties, hygroscopic performance (e.g. wicking height, drip diffusion, and permeability), and antibacterial performance against Escherichia coli and Staphylococcus aureus were examined. Subsequently, the optimum parameters and weave structures were analyzed and evaluated using AHC (Analytic Hierarchy Process)-TOPSIS (Technique for Order Preference by Similarity to an Ideal Solution) method. The novel fabric exhibits great wearability, antibacterial properties, dyeing properties, and hand feeling, and it shows great commercial potential and takes on a vital significance in future silk product development. [ABSTRACT FROM AUTHOR]