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1,191 results on '"Hsu, Wellington"'

9. A supramolecular polymer-collagen microparticle slurry for bone regeneration with minimal growth factor

Author

McClendon, Mark T., Ji, Wei, Greene, Allison C., Sai, Hiroaki, Sangji, M. Hussain, Sather, Nicholas A., Chen, Charlotte H., Lee, Sungsoo S., Katchko, Karina, Jeong, Soyeon Sophia, Kannan, Abhishek, Weiner, Joseph, Cook, Ralph, Driscoll, Adam, Lubbe, Ryan, Chang, Kevin, Haleem, Meraaj, Chen, Feng, Qiu, Ruomeng, Chun, Danielle, Stock, Stuart R., Hsu, Wellington K., Hsu, Erin L., and Stupp, Samuel I.

Published
2023
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12. Sarcopenia in Lumbar and Cervical Spine Surgery

Author

Staub, Jacob R., primary, Oris, Robert J., additional, Khazanchi, Rushmin, additional, Gerlach, Erik B., additional, Follett, Matthew A., additional, Divi, Srikanth N., additional, Hsu, Wellington K., additional, and Patel, Alpesh A., additional

Published
2024
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18. Bony ingrowth potential of 3D-printed porous titanium alloy: a direct comparison of interbody cage materials in an in vivo ovine lumbar fusion model

Author

McGilvray, Kirk C, Easley, Jeremiah, Seim, Howard B, Regan, Daniel, Berven, Sigurd H, Hsu, Wellington K, Mroz, Thomas E, and Puttlitz, Christian M

Subjects
Biomedical and Clinical Sciences, Clinical Sciences, Bioengineering, Alloys, Animals, Benzophenones, Biomechanical Phenomena, Bone-Anchored Prosthesis, Ketones, Lumbar Vertebrae, Osseointegration, Polyethylene Glycols, Polymers, Printing, Three-Dimensional, Prosthesis Design, Range of Motion, Articular, Sheep, Spinal Fusion, Titanium, X-Ray Microtomography, 3D porous titanium, Interbody cage, Ovine, PEEK, Spine, Spine fusion, Neurosciences, Orthopedics, Clinical sciences, Allied health and rehabilitation science
Abstract

Background contextThere is significant variability in the materials commonly used for interbody cages in spine surgery. It is theorized that three-dimensional (3D)-printed interbody cages using porous titanium material can provide more consistent bone ingrowth and biological fixation.PurposeThe purpose of this study was to provide an evidence-based approach to decision-making regarding interbody materials for spinal fusion.Study designA comparative animal study was performed.MethodsA skeletally mature ovine lumbar fusion model was used for this study. Interbody fusions were performed at L2-L3 and L4-L5 in 27 mature sheep using three different interbody cages (ie, polyetheretherketone [PEEK], plasma sprayed porous titanium-coated PEEK [PSP], and 3D-printed porous titanium alloy cage [PTA]). Non-destructive kinematic testing was performed in the three primary directions of motion. The specimens were then analyzed using micro-computed tomography (µ-CT); quantitative measures of the bony fusion were performed. Histomorphometric analyses were also performed in the sagittal plane through the interbody device. Outcome parameters were compared between cage designs and time points.ResultsFlexion-extension range of motion (ROM) was statistically reduced for the PTA group compared with the PEEK cages at 16 weeks (p-value=.02). Only the PTA cages demonstrated a statistically significant decrease in ROM and increase in stiffness across all three loading directions between the 8-week and 16-week sacrifice time points (p-value≤.01). Micro-CT data demonstrated significantly greater total bone volume within the graft window for the PTA cages at both 8 weeks and 16 weeks compared with the PEEK cages (p-value

Published
2018

35. The Drivers of Persistent Opioid Use and Its Impact on Healthcare Utilization After Elective Spine Surgery.

Author

Gerlach, Erik B., Plantz, Mark A., Swiatek, Peter R., Wu, Scott A., Arpey, Nicholas, Fei-Zhang, David, Divi, Srikanth N., Hsu, Wellington K., and Patel, Alpesh A.

Subjects
SPINAL surgery, ELECTIVE surgery, MEDICAL care use, SPINAL injections, MAGNETIC resonance imaging, MEDICAL care
Abstract

Study Design: Retrospective cohort study Objective: The aim of this study was to determine the incidence of and risk factors for persistent opioid use after elective cervical and lumbar spine procedures and to quantify postoperative healthcare utilization in this patient population. Methods: Patients were retrospectively identified who underwent elective spine surgery for either cervical or lumbar degenerative pathology between November 1, 2013, and September 30, 2018, at a single academic center. Patients were split into 2 cohorts, including patients with and without opioid use at 180-days postoperatively. Baseline patient demographics, underlying comorbidities, surgical variables, and preoperative/postoperative opioid use were assessed. Health resource utilization metrics within 1 year postoperatively (ie, imaging studies, emergency and urgent care visits, hospital readmissions, opioid prescriptions, etc.) were compared between these 2 groups. Results: 583 patients met inclusion criteria, of which 16.6% had opioid persistence after surgery. Opioid persistence was associated with ASA score ≥3 (P =.004), diabetes (P =.019), class I obesity (P =.012), and an opioid prescription in the 60 days prior to surgery (P =.006). Independent risk factors for opioid persistence assessed via multivariate regression included multi-level lumbar fusion (RR = 2.957), cervical central stenosis (RR = 2.761), and pre-operative opioid use (RR = 2.668). Opioid persistence was associated with higher rates of health care utilization, including more radiographs (P <.001), computed tomography (CT) scans (.007), magnetic resonance imaging (MRI) studies (P =.014), emergency department (ED) visits (.009), pain medicine referrals (P <.001), and spinal injections (P =.003). Conclusions: Opioid persistence is associated with higher rates of health care utilization within 1 year after elective spine surgery. [ABSTRACT FROM AUTHOR]

Published
2024
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47. Representativeness of the American Spine Registry: a comparison of patient characteristics with the National Inpatient Sample

Author

Bydon, Mohamad, primary, Sardar, Zeeshan M., additional, Michalopoulos, Giorgos D., additional, El Sammak, Sally, additional, Chan, Andrew K., additional, Carreon, Leah Y., additional, Norheim, Elizabeth, additional, Park, Paul, additional, Ratliff, John K., additional, Tumialán, Luis, additional, Pugely, Andrew J., additional, Steinmetz, Michael P., additional, Hsu, Wellington, additional, Knightly, John J., additional, Ziegenhorn, Diane M., additional, Donnelly, Patrick C., additional, Mullen, Kyle J., additional, Rykowsky, Stefan, additional, De, Ayushmita, additional, Potts, Eric A., additional, Coric, Domagoj, additional, Wang, Michael Y., additional, Qureshi, Sheeraz, additional, Sethi, Rajiv K., additional, Fu, Kai-Ming, additional, Patel, Alpesh A., additional, Yoon, S. Tim, additional, Brodke, Darrel, additional, Stroink, Ann R., additional, Bisson, Erica F., additional, Haid, Regis W., additional, Asher, Anthony L., additional, Burton, Doug, additional, Mummaneni, Praveen V., additional, and Glassman, Steven D., additional

Published
2023
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