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1. Chinese Graduate Students' Narratives and Sociolinguistic Advice on Intercultural Communication at Southern U.S. Universities

Author

Hsu, Chih-Hsin

Abstract

Although intercultural communication competence can be developed through cross-cultural experiences and dialogues (Jin, Cooper & Golding, 2016) and involving interactions (Rodenborg & Boisen, 2013), studies show that Chinese graduate students considered advanced English speakers continuously report difficulties in engaging in "intercultural communication" with Native English Speakers (NESs) in the U.S. (e.g., Gareis, 2012; Xiao & Petraki, 2007). Drawn upon co-cultural theory, the narrative-research-design study utilizing 17 scenario-hypothesized interviews reveals the experiences of eight Chinese advanced-ESL graduate students as they describe sociolinguistic struggles and cultural variations in verbal communication with the dominant linguistic group-NESs on their campuses. Four main instructive themes emerged. Specifically, participants felt misunderstood when NESs failed to understand that Chinese students' words were not literal or that their selfless words were self-centered decisions; and they insisted that truly effective intercultural communication would require effort from both sides on their host campuses. Through this underrepresented group's narratives, I outline recommendations for developing intercultural communication competencies for higher education institutions.

Published
2022

3. Long-term administration of Western diet induced metabolic syndrome in mice and causes cardiac microvascular dysfunction, cardiomyocyte mitochondrial damage, and cardiac remodeling involving caveolae and caveolin-1 expression

Author

Liu, I.-Fan, Lin, Tzu-Chieh, Wang, Shu-Chi, Yen, Chia-Hung, Li, Chia-Yang, Kuo, Hsuan-Fu, Hsieh, Chong-Chao, Chang, Chia-Yuan, Chang, Chuang-Rung, Chen, Yung-Hsiang, Liu, Yu-Ru, Lee, Tsung-Ying, Huang, Chi-Yuan, Hsu, Chih-Hsin, Lin, Shing-Jong, and Liu, Po-Len

Published
2023
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5. Exercise capacity-hemodynamics mismatch in elderly patients with pulmonary hypertension: A nationwide multicenter study from Taiwan Society of Cardiology Pulmonary Hypertension Registry (TAIPANS)

Author

Chen, Chang-Ying, Mei-Tzu, Wang, Sung, Shih-Hsien, Wu, Yih-Jer, Hsu, Chih-Hsin, Ho, Wan-Jing, Lin, Yen-Hung, Liu, Wei-Shin, Liu, Ju-Chi, Kao, Yung-Ta, Wu, Wen-Shiann, Wu, Chun-Hsien, Lei, Meng-Huan, Chen, Yu-Wei, Chen-Yu, Chien, Chiu, Yu-Wei, Dai, Zen-Kong, Lin, Tsung-Hsien, Lin, Lin, Chung, Cheng-Chih, Chung, Chang-Min, Huang, Sung-Hao, Cheng, Chin-Chang, Wu, Yen-Wen, Chao, Ting-Hsing, Hwang, Juey-Jen, Jia-Yin Hou, Charles, and Huang, Wei-Chun

Published
2024
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18. Riociguat treatment in patients with chronic thromboembolic pulmonary hypertension: Final safety data from the EXPERT registry

Author

Caneva, Jorge, Tuhay, Graciela, Diez, Mirta, Talavera, Maria Lujan, Acosta, Adriana, Vulcano, Norberto, Bosio, Martin, Maldonado, Lorena, Deleo, Sabino, Melatini, Luciano, Keogh, Anne, Kotlyar, Eugene, Feenstra, John, Dwyer, Nathan, Adams, Heath, Stevens, Wendy, Steele, Peter, Proudman, Susanna, Minson, Robert, Reeves, Glenn, Lavender, Melanie, Ng, Benjamin, Mackenzie, Michele, Barry, Lisa, Gruenberger, Margarethe, Huber, Charlotte, Lang, Irene, Tilea, Ioana, Sadushi-Kolici, Roela, Löffler-Ragg, Judith, Feistmantl, Lisa-Theresa, Evrard, Patrick, Louis, Renaud, Guiot, Julien, Naldi, Marco, De Pauw, Michel, Mehta, Sanjay, Camacho, Rafael Conde, Tovar, Patricia Parada, Londoño, Alejandro, Campo, Felipe, Garcia, Paula, Lema, Camila, Orozco-Levi, Mauricio, Martinez, William, Gomez, Juan Esteban, Nielsen-Kudsk, Jens Erik, Mellemkjaer, Soren, Anton, Ly, Altraja, Alan, Vihinen, Tapani, Vasankari, Tuija, Sitbon, Olivier, Cottin, Vincent, Têtu, Laurent, Noël-Savina, Elise, Shearman, Nicole, Tayler, Susanne, Olzik, Ilona, Kulka, Christine, Grimminger, Jan, Simon, Marcel, Nolde, Anna, Oqueka, Tim, Harbaum, Lars, Egenlauf, Benjamin, Ewert, Ralf, Schulz, Christian, Regotta, Sabine, Kramer, Tilmann, Knoop-Busch, Susanne, Gerhardt, Felix, Konstantinides, Stavros, Pitsiou, Georgia, Stanopoulos, Ioannis, Sourla, Evdokia, Mouratoglou, Sofia, Karvounis, Haralambos, Pappas, Athanasios, Georgopoulos, Dimitrios, Fanaridis, Michail, Mitrouska, Ioanna, Michalis, Lampros, Pappas, Konstantinos, Kotsia, Anna, Gaine, Sean, Vizza, Carmine Dario, Manzi, Giovanna, Poscia, Roberto, Badagliacca, Roberto, Agostoni, Piergiuseppe, Bruno, Noemi, Farina, Stefania, D'Alto, Michele, Argiento, Paola, Correra, Anna, Di Marco, Giovanni Maria, Cresci, Chiara, Vannucchi, Vieri, Torricelli, Elena, Garcea, Alessio, Pesci, Alberto, Sardella, Luca, Paciocco, Giuseppe, Pane, Federico, D'Armini, Andrea Maria, Pin, Maurizio, Grazioli, Valentina, Massola, Giulia, Sciortino, Antonio, Prediletto, Renato, Bauleo, Carolina, Airò, Edoardo, Ndreu, Rudina, Pavlickova, Ivana, Lunardi, Claudio, Mulè, Massimiliano, Farruggio, Silvia, Costa, Serena, Galgano, Giuseppe, Petruzzi, Mario, De Luca, Anna, Lombardi, Francesco, Roncon, Loris, Conte, Luca, Picariello, Claudio, Wirtz, Gil, Alexandre, Myriam, Vonk-Noordegraaf, A., Boogaard, H., Mager, J., Reesink, H., van den Toorn, Leon M., Boomars, Karin, Andreassen, Arne K., Castro, Graça, Tania, Gonçalves, Baptista, Rui, Marinho, António, Shiang, Teresa, Oliveira, Ana, Coutinho, Daniel, Sousa, Joana, Loureiro, Maria José, Repolho, Débora, Martins Jesus, Susana Maria, Capinha, Marta, Agostinho, João, Cardoso, Tania, Rocha, Andreia, Espinha, Mafalda, Ivanov, Kyundyul Ivanovich, Alexeeva, Dalyana Eduardovna, Batalina, Marina Vadimovna, Hegya, Daria Viktorovna, Zvereva, Tatyana Nikolaevna, Avdeev, Sergey Nikolaevich, Tsareva, Natalia Anatolievna, Galyavich, Albert Sarvatovich, Nikolaevich, Bykov Aleksander, Filippov, Evgeny Vladimirovich, Yakovleva, Olga Eduardovna, Pavlova, Olga Borisovna, Skripkina, Elena Sergeevna, Martynyuk, Tamila Vitalievna, Bukatova, Irina Fedorovna, Tregubova, Anna Viktorovna, Platonov, Dmitry Yurievich, Kolomeytseva, Tatyana Mikhaylovna, Al Dalaan, Abdullah, Abdelsayed, Abeer Abeer, Weheba, Ihab, Saleemi, Sarferaz, Sakkijha, Hussam, Bohacekova, Marcela, Valkovicova, Tatiana, Farkasova, Iveta, Quezada, Carlos Andres, Piccari, Lucilla, Blanco, Isabel, Sebastian, Laura, Roman, Antonio, Lopez, Manuel, Otero, Remedios, Elias, Teresa, Jara, Luis, Asencio, Isabel, Arjona, Josefa Jiménez, Almagro, Raúl Menor, Cárdenas, Salvador López, García, Salvador Alcaraz, Rodríguez, Patricia Villanueva, Lopez, Raquel, Garcia, Alberto, Avilés, Francisco Fernandez, De La Pava, Sebastian, Yotti, Raquel, Peñate, Gregorio Pérez, Marrero, Fernando León, Cifrián Martínez, José Manuel, Martinez-Meñaca, Amaya, Alonso, Lecue Pilar, Rozas, Sonia Fernandez, Fernandez, David Iturbe, Cuesta, Victor Mora, Söderberg, Stefan, Bartfay, Sven-Erik, Rundqvist, Bengt, Alfetlawi, Monthir, Wodlin, Peter, Schwarz, Esther Irene, Speich, Rudolf, Lador, Frédéric, Rochat, Thierry, Gasche-Soccal, Paola, Hsu, Chih-Hsin, Lin, Tsung-Hsien, Su, Ho-Ming, Lai, Wen-Ter, Chu, Chun Yuan, Hsu, Po-Chao, Voon, Wen-Chol, Yen, Hsueh-Wei, Yih-Jer Wu, Jacob, Wu, Shu-Hao, Huang, Wen-Pin, Fong, Man-Cai, Huang, Chien-Lung, Kuo, Ping-Hung, Lin, Yen-Hung, Lin, Jiunn-Lee, Hung, Chi-Sheng, Wu, Cho-Kai, Sung, Shih-Hsien, Huang, Wei-Chun, Cheng, Chin-Chang, Kuo, Shu-Hung, Wang, Wen-Hwa, Ho, Wan-Jing, Hsu, Tsu-Shiu, Mutlu, Bülent, Atas, Halil, Ongen, Gul, Un, Zeynep, Okumus, Gulfer, Hanta, Ismail, Corris, Paul, Peacock, Andrew, Church, Colin, Toshner, Mark, Newnham, Michael, Ghofrani, Hossein-Ardeschir, Gomez Sanchez, Miguel-Angel, Humbert, Marc, Pittrow, David, Simonneau, Gérald, Gall, Henning, Grünig, Ekkehard, Klose, Hans, Halank, Michael, Langleben, David, Snijder, Repke J., Escribano Subias, Pilar, Mielniczuk, Lisa M., Lange, Tobias J., Vachiéry, Jean-Luc, Wirtz, Hubert, Helmersen, Douglas S., Tsangaris, Iraklis, Barberá, Joan A., Pepke-Zaba, Joanna, Boonstra, Anco, Rosenkranz, Stephan, Ulrich, Silvia, Steringer-Mascherbauer, Regina, Delcroix, Marion, Jansa, Pavel, Šimková, Iveta, Giannakoulas, George, Klotsche, Jens, Williams, Evgenia, Meier, Christian, and Hoeper, Marius M.

Published
2021
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19. Riociguat treatment in patients with pulmonary arterial hypertension: Final safety data from the EXPERT registry

Author

Caneva, Jorge, Tuhay, Graciela, Diez, Mirta, Talavera, Maria Lujan, Acosta, Adriana, Vulcano, Norberto, Bosio, Martin, Maldonado, Lorena, Deleo, Sabino, Melatini, Luciano, Keogh, Anne, Kotlyar, Eugene, Feenstra, John, Dwyer, Nathan, Adams, Heath, Stevens, Wendy, Steele, Peter, Proudman, Susanna, Minson, Robert, Reeves, Glenn, Lavender, Melanie, Ng, Benjamin, Mackenzie, Michele, Barry, Lisa, Gruenberger, Margarethe, Huber, Charlotte, Lang, Irene, Tilea, Ioana, Sadushi-Kolici, Roela, Löffler-Ragg, Judith, Feistmantl, Lisa-Theresa, Evrard, Patrick, Guiot, Julien, Naldi, Marco, De Pauw, Michel, Louis, Renaud, Mehta, Sanjay, Camacho, Rafael Conde, Tovar, Patricia Parada, Londoño, Alejandro, Campo, Felipe, Garcia, Paula, Lema, Camila, Orozco-Levi, Mauricio, Martinez, William, Gomez, Juan Esteban, Nielsen-Kudsk, Jens Erik, Mellemkjaer, Soren, Anton, Ly, Altraja, Alan, Vihinen, Tapani, Vasankari, Tuija, Sitbon, Olivier, Cottin, Vincent, Têtu, Laurent, Noël-Savina, Elise, Shearman, Nicole, Tayler, Susanne, Olzik, Ilona, Kulka, Christine, Grimminger, Jan, Simon, Marcel, Nolde, Anna, Oqueka, Tim, Harbaum, Lars, Egenlauf, Benjamin, Ewert, Ralf, Schulz, Christian, Regotta, Sabine, Kramer, Tilmann, Knoop-Busch, Susanne, Gerhardt, Felix, Konstantinides, Stavros, Pitsiou, Georgia, Stanopoulos, Ioannis, Sourla, Evdokia, Mouratoglou, Sofia, Karvounis, Haralambos, Pappas, Athanasios, Mitrouska, Ioanna, Georgopoulos, Dimitrios, Fanaridis, Michail, Michalis, Lampros, Pappas, Konstantinos, Kotsia, Anna, Gaine, Sean, Vizza, Carmine Dario, Manzi, Giovanna, Poscia, Roberto, Badagliacca, Roberto, Agostoni, Piergiuseppe, Bruno, Noemi, Farina, Stefania, D'Alto, Michele, Argiento, Paola, Correra, Anna, Di Marco, Giovanni Maria, Cresci, Chiara, Vannucchi, Vieri, Torricelli, Elena, Garcea, Alessio, Pesci, Alberto, Sardella, Luca, Paciocco, Giuseppe, Pane, Federico, D'Armini, Andrea Maria, Pin, Maurizio, Grazioli, Valentina, Massola, Giulia, Sciortino, Antonio, Prediletto, Renato, Bauleo, Carolina, Airò, Edoardo, Ndreu, Rudina, Pavlickova, Ivana, Lunardi, Claudio, Farruggio, Silvia, Costa, Serena, Mulè, Massimiliano, Galgano, Giuseppe, Petruzzi, Mario, De Luca, Anna, Lombardi, Francesco, Roncon, Loris, Conte, Luca, Picariello, Claudio, Wirtz, Gil, Alexandre, Myriam, Vonk-Noordegraaf, A., Boogaard, H., Mager, J., Reesink, H., van den Toorn, Leon M., Boomars, Karin, Andreassen, Arne K., Castro, Graça, Tania, Gonçalves, Baptista, Rui, Marinho, António, Shiang, Teresa, Oliveira, Ana, Coutinho, Daniel, Sousa, Joana, Loureiro, Maria José, Repolho, Débora, Martins Jesus, Susana Maria, Capinha, Marta, Agostinho, João, Cardoso, Tania, Rocha, Andreia, Espinha, Mafalda, Ivanov, Kyundyul Ivanovich, Alexeeva, Dalyana Eduardovna, Batalina, Marina Vadimovna, Hegya, Daria Viktorovna, Zvereva, Tatyana Nikolaevna, Avdeev, Sergey Nikolaevich, Tsareva, Natalia Anatolievna, Galyavich, Albert Sarvatovich, Nikolaevich, Bykov Aleksander, Filippov, Evgeny Vladimirovich, Yakovleva, Olga Eduardovna, Pavlova, Olga Borisovna, Skripkina, Elena Sergeevna, Martynyuk, Tamila Vitalievna, Bukatova, Irina Fedorovna, Tregubova, Anna Viktorovna, Platonov, Dmitry Yurievich, Kolomeytseva, Tatyana Mikhaylovna, Al Dalaan, Abdullah, Abdelsayed, Abeer Abeer, Weheba, Ihab, Saleemi, Sarferaz, Sakkijha, Hussam, Bohacekova, Marcela, Valkovicova, Tatiana, Farkasova, Iveta, Quezada, Carlos Andres, Piccari, Lucilla, Blanco, Isabel, Sebastian, Laura, Roman, Antonio, Lopez, Manuel, Otero, Remedios, Elias, Teresa, Jara, Luis, Asencio, Isabel, Arjona, Josefa Jiménez, Almagro, Raúl Menor, Cárdenas, Salvador López, García, Salvador Alcaraz, Rodríguez, Patricia Villanueva, Lopez, Raquel, Garcia, Alberto, Avilés, Francisco Fernandez, De La Pava, Sebastian, Yotti, Raquel, Peñate, Gregorio Pérez, Marrero, Fernando León, Cifrián Martínez, José Manuel, Martinez-Meñaca, Amaya, Alonso, Lecue Pilar, Rozas, Sonia Fernandez, Fernandez, David Iturbe, Cuesta, Victor Mora, Söderberg, Stefan, Bartfay, Sven-Erik, Rundqvist, Bengt, Alfetlawi, Monthir, Wodlin, Peter, Schwarz, Esther Irene, Speich, Rudolf, Lador, Frédéric, Rochat, Thierry, Gasche-Soccal, Paola, Hsu, Chih-Hsin, Lin, Tsung-Hsien, Su, Ho-Ming, Lai, Wen-Ter, Chu, Chun Yuan, Hsu, Po-Chao, Voon, Wen-Chol, Yen, Hsueh-Wei, Yih-Jer Wu, Jacob, Wu, Shu-Hao, Huang, Wen-Pin, Fong, Man-Cai, Huang, Chien-Lung, Kuo, Ping-Hung, Lin, Yen-Hung, Lin, Jiunn-Lee, Hung, Chi-Sheng, Wu, Cho-Kai, Sung, Shih-Hsien, Huang, Wei-Chun, Cheng, Chin-Chang, Kuo, Shu-Hung, Wang, Wen-Hwa, Ho, Wan-Jing, Hsu, Tsu-Shiu, Mutlu, Bülent, Atas, Halil, Ongen, Gul, Un, Zeynep, Okumus, Gulfer, Hanta, Ismail, Corris, Paul, Peacock, Andrew, Church, Colin, Toshner, Mark, Newnham, Michael, Hoeper, Marius M., Gomez Sanchez, Miguel-Angel, Humbert, Marc, Pittrow, David, Simonneau, Gérald, Gall, Henning, Grünig, Ekkehard, Klose, Hans, Halank, Michael, Langleben, David, Snijder, Repke J., Escribano Subias, Pilar, Mielniczuk, Lisa M., Lange, Tobias J., Vachiéry, Jean-Luc, Wirtz, Hubert, Helmersen, Douglas S., Tsangaris, Iraklis, Barberà, Joan A., Pepke-Zaba, Joanna, Boonstra, Anco, Rosenkranz, Stephan, Ulrich, Silvia, Steringer-Mascherbauer, Regina, Delcroix, Marion, Jansa, Pavel, Šimková, Iveta, Giannakoulas, George, Klotsche, Jens, Williams, Evgenia, Meier, Christian, and Ghofrani, Hossein-Ardeschir

Published
2021
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21. The long-term outcome of chronic thromboembolic pulmonary hypertension: Pulmonary endarterectomy and balloon pulmonary angioplasty

Author

Yang, Kuo-Ming, primary, Wang, Mei-Tzu, additional, Tao, Chi-Wei, additional, Wu, Yih-Jer, additional, Hsu, Chih-Hsin, additional, Liao, Wei-Chih, additional, Hsu, Hsao-Hsun, additional, Lin, Meng-Chih, additional, Tsai, Fu-Ting, additional, Fu, Yun-Ju, additional, Kuo, Feng-Yu, additional, Cheng, Chin-Chang, additional, Hung, Cheng-Chung, additional, Wang, Hao-Chien, additional, Yu, Chong-Jen, additional, and Huang, Wei-Chun, additional

Published
2024
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26. The Obesity-Mortality Paradox in Patients With Heart Failure in Taiwan and a Collaborative Meta-Analysis for East Asian Patients

Author

Chan, Kuei-Chuan, Chang, Heng-Chia, Chang, Kuan-Cheng, Chen, Zhih-Cherng, Chen, Shyh-Ming, Chu, Pao-Hsien, Hsu, Chih-Hsin, Huang, Jin-Long, Kuo, Jen yuan, Lin, Jiunn-Lee, Lin, Wei-Shiang, Mar, Guang-Yuan, Shyu, Kou-Gi, Sung, Shih-Hsien, Tseng, Wei-Kung, Voon, Wen-Chol, Wang, Ji-Hung, Wen, Ming-Shien, Wu, Chih-Cheng, Wu, Yen-Wen, Yang, Ning-I., Yin, Wei-Hsian, Lin, Gen-Min, Li, Yi-Hwei, Wang, Chun-Chieh, and Yeh, San-Jou

Published
2016
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27. 2023 Taiwan Society of Cardiology (TSOC) and Taiwan College of Rheumatology (TCR) Joint Consensus on Connective Tissue Disease-Associated Pulmonary Arterial Hypertension

Author

Huang, Wei-Chun, Hsieh, Song-Chou, Wu, Yen-Wen, Hsieh, Tsu-Yi, Wu, Yih-Jer, Li, Ko-Jen, Charng, Min-Ji, Chen, Wei-Sheng, Sung, Shih-Hsien, Tsao, Yen-Po, Ho, Wan-Jing, Lai, Chien-Chih, Cheng, Chin-Chang, Tsai, Hung-Cheng, Hsu, Chih-Hsin, Lu, Cheng-Hsun, Chiu, Yu-Wei, Shen, Chieh-Yu, Wu, Chun-Hsien, Liu, Feng-Cheng, Lin, Yen-Hung, Yeh, Fu-Chiang, Liu, Wei-Shin, Lee, Hui-Ting, Wu, Shu-Hao, Chang, Chi-Ching, Chu, Chun-Yuan, Hou, Charles Jia-Yin, and Tsai, Chang-Youh

Subjects
Consensus
Abstract

BACKGROUND: Pulmonary arterial hypertension (PAH), defined as the presence of a mean pulmonary artery pressure > 20 mmHg, pulmonary artery wedge pressure ≤ 15 mmHg, and pulmonary vascular resistance (PVR) > 2 Wood units based on expert consensus, is characterized by a progressive and sustained increase in PVR, which may lead to right heart failure and death. PAH is a well-known complication of connective tissue diseases (CTDs), such as systemic sclerosis, systemic lupus erythematosus, Sjogren’s syndrome, and other autoimmune conditions. In the past few years, tremendous progress in the understanding of PAH pathogenesis has been made, with various novel diagnostic and screening methods for the early detection of PAH proposed worldwide. OBJECTIVES: This study aimed to obtain a comprehensive understanding and provide recommendations for the management of CTD-PAH in Taiwan, focusing on its clinical importance, prognosis, risk stratification, diagnostic and screening algorithm, and pharmacological treatment. METHODS: The members of the Taiwan Society of Cardiology (TSOC) and Taiwan College of Rheumatology (TCR) reviewed the related literature thoroughly and integrated clinical trial evidence and real-world clinical experience for the development of this consensus. CONCLUSIONS: Early detection by regularly screening at-risk patients with incorporations of relevant autoantibodies and biomarkers may lead to better outcomes of CTD-PAH. This consensus proposed specific screening flowcharts for different types of CTDs, the risk assessment tools applicable to the clinical scenario in Taiwan, and a recommendation of medications in the management of CTD-PAH.

Published
2023

28. The Effects of Post-Acute Care in Patients with Heart Failure in Taiwan: A Single Center Experience

Author

Wang, Pei-Yi, Lin, Wen-Chih, Hsieh, Pei-Chun, Lin, Sheng-Hsiang, Liu, Ping-Yen, Chao, Ting-Hsing, and Hsu, Chih-Hsin

Subjects
Original Article
Abstract

BACKGROUND: The National Health Insurance Administration in Taiwan has promoted the heart failure post-acute care (HF-PAC) program as a means to provide proactive integrated care within the optimal treatment timeframe to enhance functional recovery after acute decompensated heart failure (HF). OBJECTIVES: The aim of this program was to reduce HF readmission rates, improved medication prescription rates, and improve the quality of life in HF patients. METHODS: Patients who had a reduced left ventricular ejection fraction (LVEF) of ≤ 40% were included and followed up for 6 months after discharge. They underwent cardiac rehabilitation and physiological, and nutritional status evaluations. The main clinical outcomes of the HF-PAC program were guideline-directed medical therapy prescription rate and 6-month readmission rate. RESULTS: A total of 122 patients were recruited from June 2018 to December 2020 at a medical center in southern Taiwan. The patients’ activities of daily living, nutritional status, quality of life and LVEF were significantly improved during the HF-PAC program. More than 95% of the patients received guideline-directed medical prescriptions at the end of the HF-PAC program. The cardiovascular-related 6-month re-admission rate after the HF-PAC program ended was 27.7%, and it could be predicted by the New York Health Association functional class [hazard ratio (HR) 95% confidence interval (95% CI) = 4.12 (1.36-12.46)], value of the Mini Nutritional Assessment - Short Form [HR (95% CI) = 0.46 (0.31-0.68)] and LVEF [HR (95% CI) = 0.95 (0.91-0.99)]. CONCLUSIONS: By incorporating multidisciplinary healthcare teams, the HF-PAC program improves the guideline- directed medical therapy prescription rate, thus improving patients’ cardiac function, physical activity recovery, the quality of life, and also reduces their readmission rate.

Published
2023

33. ISHLT consensus statement: Perioperative management of patients with pulmonary hypertension and right heart failure undergoing surgery

Author

McGlothlin, Dana P., primary, Granton, John, additional, Klepetko, Walter, additional, Beghetti, Maurice, additional, Rosenzweig, Erika B., additional, Corris, Paul A., additional, Horn, Evelyn, additional, Kanwar, Manreet K., additional, McRae, Karen, additional, Roman, Antonio, additional, Tedford, Ryan, additional, Badagliacca, Roberto, additional, Bartolome, Sonja, additional, Benza, Raymond, additional, Caccamo, Marco, additional, Cogswell, Rebecca, additional, Dewachter, Celine, additional, Donahoe, Laura, additional, Fadel, Elie, additional, Farber, Harrison W., additional, Feinstein, Jeffrey, additional, Franco, Veronica, additional, Frantz, Robert, additional, Gatzoulis, Michael, additional, Hwa (Anne) Goh, Choon, additional, Guazzi, Marco, additional, Hansmann, Georg, additional, Hastings, Stuart, additional, Heerdt, Paul M., additional, Hemnes, Anna, additional, Herpain, Antoine, additional, Hsu, Chih-Hsin, additional, Kerr, Kim, additional, Kolaitis, Nicholas A., additional, Kukreja, Jasleen, additional, Madani, Michael, additional, McCluskey, Stuart, additional, McCulloch, Michael, additional, Moser, Bernhard, additional, Navaratnam, Manchula, additional, Rådegran, Göran, additional, Reimer, Cara, additional, Savale, Laurent, additional, Shlobin, Oksana A., additional, Svetlichnaya, Jana, additional, Swetz, Keith, additional, Tashjian, Jessica, additional, Thenappan, Thenappan, additional, Vizza, Carmine Dario, additional, West, Shawn, additional, Zuckerman, Warren, additional, Zuckermann, Andreas, additional, and De Marco, Teresa, additional

Published
2022
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34. Prothymosin α Gene Transfer Modulates Myocardial Remodeling after Ischemia-Reperfusion Injury

Author

Shiau, Ai-Li, Fang, Shih-Yuan, Hsu, Chih-Hsin, Chiu, Meng-Hsuan, Lam, Chen-Fuh, Wu, Chao-Liang, and Roan, Jun-Neng

Subjects
natural sciences, Original Article
Abstract

BACKGROUND: Prothymosin α (ProT), a polypeptide, attenuates inflammation and inhibits transforming growth factor (TGF)-β signaling in pulmonary tissues. We investigated the potential role of ProT in myocardial ischemia-reperfusion (MyoIR) injury using ProT cDNA transfer. METHODS: Serum ProT levels were investigated in cardiogenic shock patients with MyoIR (n = 9). In addition, the myocardium of Sprague-Dawley rats (n = 52) was subjected to 25 min of ischemia followed by an injection of adenoviral vectors (2 × 10(9) plaque-forming units) carrying ProT or the luciferase gene, 10 min before reperfusion. Echocardiography, serum ProT, and biochemical analyses of organ functions were performed before euthanasia, 14 days after treatment. Immunohistochemistry and immunoblotting of the myocardial tissue were also performed. RESULTS: Serum ProT levels were transiently elevated in the rats and patients early after MyoIR, which was reduced to baseline levels in control rats and patients. ProT gene transfer persistently mobilized ProT serum levels, reduced dilatation, attenuated fibrotic changes, and preserved the left ventricular ejection fraction after MyoIR. Tissue thrombospondin-1 level was abundant, and matrix metalloproteinase-2, collagen I, and collagen IV levels were decreased in the treatment group. While TGF-β protein level remained stable, ProT transduction mobilized Smad7, which counteracted TGF-β. ProT reduced tissue microRNA-223 expression, inhibited the associated interleukin-1β, and preserved RAS p21 protein activator 1 protein abundance. CONCLUSIONS: An increase in transient serum ProT levels could be a protective response in the acute stage of MyoIR. ProT gene transfer further preserved ventricular morphology and function through anti-inflammatory and anti-fibrotic effects in the subacute stage after injury.

Published
2022

36. Advances of Thrombectomy in Venous Thromboembolism

Author

Hsu, Chih-Hsin, Chen, Po-Sheng, Lin, Jia-Ling, and Yang, Po-Kai

Subjects
Medical
Abstract

Venous thromboembolism (VTE) presenting as deep vein thrombosis and pulmonary embolism clinically is a potentially fatal cardiovascular diseases with short-term and long-term sequelae. Furthermore, there is high recurrent rate in VTE patients during follow-up. Anticoagulation with traditional anticoagulants or new generation of oral anticoagulants is the gold standard treatment in patients with VTE. On the other hand, there is remarkable progression in device-based or surgical thrombectomy in managements of VTE in recent years. Current evidence also demonstrates the efficacy and safety of these invasive procedures in selective VTE patients. The present article will illustrate recent advances of device-based or surgical thrombectomy in VTE treatment.

Published
2022

40. Influence of confirmed viral infection on adult acute fulminant myocarditis supported with extracorporeal membrane oxygenation.

Author

Kuo, Lan‐Pin, Tsai, Meng‐Ta, Wang, Yi‐Chen, Hsu, Chih‐Hsin, Lin, Wei‐Hung, Wang, Wei‐Ming, Shih, Chao‐Jung, Yang, Pei‐Ni, Hu, Yu‐Ning, and Roan, Jun‐Neng

Subjects
EXTRACORPOREAL membrane oxygenation, VIRUS diseases, POSITIVE end-expiratory pressure, MYOCARDITIS, RENAL replacement therapy
Abstract

Background: The impact of etiologies of acute fulminant myocarditis (AFM), which requires extracorporeal membrane oxygenation (ECMO), on clinical outcomes remains unknown. This study aimed to investigate the risk factors for ECMO weaning and mortality among patients with AFM due to viral etiologies in a tertiary referral medical center. Methods: We included 33 adults with AFM who received ECMO and were admitted between January 2002 and January 2021. General demographics, laboratory data, echocardiography findings, and long‐term outcomes were analyzed for confirmed viral etiology and unconfirmed etiology groups. Results: The overall hospital survival rate was 54.5%. The age, sex, severity of the hemodynamic condition, and cardiac rhythm were similar between the two groups. Multivariate Cox regression analysis revealed that a confirmed viral etiology (HR 4.201, 95% CI 1.061–16.666), peri‐ECMO renal replacement therapy (RRT) (HR 9.804, 1.140–83.333) and a high positive end‐expiratory pressure (PEEP) in the ventilator settings at 24 h after ECMO (HR 1.479, 1.020–2.143) were significant prognostic factors for in‐hospital mortality. Peri‐ECMO RRT was also a significant negative prognostic factor for successful ECMO weaning (OR 0.061, 0.006–0.600) in the multivariate logistic model. Conclusions: Among AFM patients receiving ECMO support, RRT use was associated with a decreased chance of survival to ECMO weaning. Multiple organ dysfunction and a high PEEP were also predictive of a lower chance of hospital survival. Those with a confirmed diagnosis of viral myocarditis may require more medical attention due to the higher risk of hospital mortality than those without a definite diagnosis. [ABSTRACT FROM AUTHOR]

Published
2023
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41. Endocardial Endothelial Dysfunction and Unknown Polymorphic Composite Accumulation in Heart Failure

Author

Kuo, Hsuan-Fu, primary, Liu, I-Fan, additional, Li, Chia-Yang, additional, Tsai, Chien-Sung, additional, Chen, Yung-Hsiang, additional, Lian, Wei-Shiung, additional, Lin, Tzu-Chieh, additional, Liu, Yu-Ru, additional, Lee, Tsung-Ying, additional, Huang, Chi-Yuan, additional, Hsieh, Chong-Chao, additional, Hsu, Chih-Hsin, additional, Lin, Feng-Yen, additional, and Liu, Po-Len, additional

Published
2021
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42. miR-29a-3p/THBS2 Axis Regulates PAH-Induced Cardiac Fibrosis

Author

Hsu, Chih-Hsin, primary, Liu, I-Fan, additional, Kuo, Hsuan-Fu, additional, Li, Chia-Yang, additional, Lian, Wei-Shiung, additional, Chang, Chia-Yuan, additional, Chen, Yung-Hsiang, additional, Liu, Wei-Lun, additional, Lu, Chi-Yu, additional, Liu, Yu-Ru, additional, Lin, Tzu-Chieh, additional, Lee, Tsung-Ying, additional, Huang, Chi-Yuan, additional, Hsieh, Chong-Chao, additional, and Liu, Po-Len, additional

Published
2021
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50. Riociguat treatment in patients with chronic thromboembolic pulmonary hypertension: Final safety data from the EXPERT registry

Author

Ghofrani, Hossein-Ardeschir, primary, Gomez Sanchez, Miguel-Angel, additional, Humbert, Marc, additional, Pittrow, David, additional, Simonneau, Gérald, additional, Gall, Henning, additional, Grünig, Ekkehard, additional, Klose, Hans, additional, Halank, Michael, additional, Langleben, David, additional, Snijder, Repke J., additional, Escribano Subias, Pilar, additional, Mielniczuk, Lisa M., additional, Lange, Tobias J., additional, Vachiéry, Jean-Luc, additional, Wirtz, Hubert, additional, Helmersen, Douglas S., additional, Tsangaris, Iraklis, additional, Barberá, Joan A., additional, Pepke-Zaba, Joanna, additional, Boonstra, Anco, additional, Rosenkranz, Stephan, additional, Ulrich, Silvia, additional, Steringer-Mascherbauer, Regina, additional, Delcroix, Marion, additional, Jansa, Pavel, additional, Šimková, Iveta, additional, Giannakoulas, George, additional, Klotsche, Jens, additional, Williams, Evgenia, additional, Meier, Christian, additional, Hoeper, Marius M., additional, Caneva, Jorge, additional, Tuhay, Graciela, additional, Diez, Mirta, additional, Talavera, Maria Lujan, additional, Acosta, Adriana, additional, Vulcano, Norberto, additional, Bosio, Martin, additional, Maldonado, Lorena, additional, Deleo, Sabino, additional, Melatini, Luciano, additional, Keogh, Anne, additional, Kotlyar, Eugene, additional, Feenstra, John, additional, Dwyer, Nathan, additional, Adams, Heath, additional, Stevens, Wendy, additional, Steele, Peter, additional, Proudman, Susanna, additional, Minson, Robert, additional, Reeves, Glenn, additional, Lavender, Melanie, additional, Ng, Benjamin, additional, Mackenzie, Michele, additional, Barry, Lisa, additional, Gruenberger, Margarethe, additional, Huber, Charlotte, additional, Lang, Irene, additional, Tilea, Ioana, additional, Sadushi-Kolici, Roela, additional, Löffler-Ragg, Judith, additional, Feistmantl, Lisa-Theresa, additional, Evrard, Patrick, additional, Louis, Renaud, additional, Guiot, Julien, additional, Naldi, Marco, additional, De Pauw, Michel, additional, Mehta, Sanjay, additional, Camacho, Rafael Conde, additional, Tovar, Patricia Parada, additional, Londoño, Alejandro, additional, Campo, Felipe, additional, Garcia, Paula, additional, Lema, Camila, additional, Orozco-Levi, Mauricio, additional, Martinez, William, additional, Gomez, Juan Esteban, additional, Nielsen-Kudsk, Jens Erik, additional, Mellemkjaer, Soren, additional, Anton, Ly, additional, Altraja, Alan, additional, Vihinen, Tapani, additional, Vasankari, Tuija, additional, Sitbon, Olivier, additional, Cottin, Vincent, additional, Têtu, Laurent, additional, Noël-Savina, Elise, additional, Shearman, Nicole, additional, Tayler, Susanne, additional, Olzik, Ilona, additional, Kulka, Christine, additional, Grimminger, Jan, additional, Simon, Marcel, additional, Nolde, Anna, additional, Oqueka, Tim, additional, Harbaum, Lars, additional, Egenlauf, Benjamin, additional, Ewert, Ralf, additional, Schulz, Christian, additional, Regotta, Sabine, additional, Kramer, Tilmann, additional, Knoop-Busch, Susanne, additional, Gerhardt, Felix, additional, Konstantinides, Stavros, additional, Pitsiou, Georgia, additional, Stanopoulos, Ioannis, additional, Sourla, Evdokia, additional, Mouratoglou, Sofia, additional, Karvounis, Haralambos, additional, Pappas, Athanasios, additional, Georgopoulos, Dimitrios, additional, Fanaridis, Michail, additional, Mitrouska, Ioanna, additional, Michalis, Lampros, additional, Pappas, Konstantinos, additional, Kotsia, Anna, additional, Gaine, Sean, additional, Vizza, Carmine Dario, additional, Manzi, Giovanna, additional, Poscia, Roberto, additional, Badagliacca, Roberto, additional, Agostoni, Piergiuseppe, additional, Bruno, Noemi, additional, Farina, Stefania, additional, D'Alto, Michele, additional, Argiento, Paola, additional, Correra, Anna, additional, Di Marco, Giovanni Maria, additional, Cresci, Chiara, additional, Vannucchi, Vieri, additional, Torricelli, Elena, additional, Garcea, Alessio, additional, Pesci, Alberto, additional, Sardella, Luca, additional, Paciocco, Giuseppe, additional, Pane, Federico, additional, D'Armini, Andrea Maria, additional, Pin, Maurizio, additional, Grazioli, Valentina, additional, Massola, Giulia, additional, Sciortino, Antonio, additional, Prediletto, Renato, additional, Bauleo, Carolina, additional, Airò, Edoardo, additional, Ndreu, Rudina, additional, Pavlickova, Ivana, additional, Lunardi, Claudio, additional, Mulè, Massimiliano, additional, Farruggio, Silvia, additional, Costa, Serena, additional, Galgano, Giuseppe, additional, Petruzzi, Mario, additional, De Luca, Anna, additional, Lombardi, Francesco, additional, Roncon, Loris, additional, Conte, Luca, additional, Picariello, Claudio, additional, Wirtz, Gil, additional, Alexandre, Myriam, additional, Vonk-Noordegraaf, A., additional, Boogaard, H., additional, Mager, J., additional, Reesink, H., additional, van den Toorn, Leon M., additional, Boomars, Karin, additional, Andreassen, Arne K., additional, Castro, Graça, additional, Tania, Gonçalves, additional, Baptista, Rui, additional, Marinho, António, additional, Shiang, Teresa, additional, Oliveira, Ana, additional, Coutinho, Daniel, additional, Sousa, Joana, additional, Loureiro, Maria José, additional, Repolho, Débora, additional, Martins Jesus, Susana Maria, additional, Capinha, Marta, additional, Agostinho, João, additional, Cardoso, Tania, additional, Rocha, Andreia, additional, Espinha, Mafalda, additional, Ivanov, Kyundyul Ivanovich, additional, Alexeeva, Dalyana Eduardovna, additional, Batalina, Marina Vadimovna, additional, Hegya, Daria Viktorovna, additional, Zvereva, Tatyana Nikolaevna, additional, Avdeev, Sergey Nikolaevich, additional, Tsareva, Natalia Anatolievna, additional, Galyavich, Albert Sarvatovich, additional, Nikolaevich, Bykov Aleksander, additional, Filippov, Evgeny Vladimirovich, additional, Yakovleva, Olga Eduardovna, additional, Pavlova, Olga Borisovna, additional, Skripkina, Elena Sergeevna, additional, Martynyuk, Tamila Vitalievna, additional, Bukatova, Irina Fedorovna, additional, Tregubova, Anna Viktorovna, additional, Platonov, Dmitry Yurievich, additional, Kolomeytseva, Tatyana Mikhaylovna, additional, Al Dalaan, Abdullah, additional, Abdelsayed, Abeer Abeer, additional, Weheba, Ihab, additional, Saleemi, Sarferaz, additional, Sakkijha, Hussam, additional, Bohacekova, Marcela, additional, Valkovicova, Tatiana, additional, Farkasova, Iveta, additional, Quezada, Carlos Andres, additional, Piccari, Lucilla, additional, Blanco, Isabel, additional, Sebastian, Laura, additional, Roman, Antonio, additional, Lopez, Manuel, additional, Otero, Remedios, additional, Elias, Teresa, additional, Jara, Luis, additional, Asencio, Isabel, additional, Arjona, Josefa Jiménez, additional, Almagro, Raúl Menor, additional, Cárdenas, Salvador López, additional, García, Salvador Alcaraz, additional, Rodríguez, Patricia Villanueva, additional, Lopez, Raquel, additional, Garcia, Alberto, additional, Avilés, Francisco Fernandez, additional, De La Pava, Sebastian, additional, Yotti, Raquel, additional, Peñate, Gregorio Pérez, additional, Marrero, Fernando León, additional, Cifrián Martínez, José Manuel, additional, Martinez-Meñaca, Amaya, additional, Alonso, Lecue Pilar, additional, Rozas, Sonia Fernandez, additional, Fernandez, David Iturbe, additional, Cuesta, Victor Mora, additional, Söderberg, Stefan, additional, Bartfay, Sven-Erik, additional, Rundqvist, Bengt, additional, Alfetlawi, Monthir, additional, Wodlin, Peter, additional, Schwarz, Esther Irene, additional, Speich, Rudolf, additional, Lador, Frédéric, additional, Rochat, Thierry, additional, Gasche-Soccal, Paola, additional, Hsu, Chih-Hsin, additional, Lin, Tsung-Hsien, additional, Su, Ho-Ming, additional, Lai, Wen-Ter, additional, Chu, Chun Yuan, additional, Hsu, Po-Chao, additional, Voon, Wen-Chol, additional, Yen, Hsueh-Wei, additional, Yih-Jer Wu, Jacob, additional, Wu, Shu-Hao, additional, Huang, Wen-Pin, additional, Fong, Man-Cai, additional, Huang, Chien-Lung, additional, Kuo, Ping-Hung, additional, Lin, Yen-Hung, additional, Lin, Jiunn-Lee, additional, Hung, Chi-Sheng, additional, Wu, Cho-Kai, additional, Sung, Shih-Hsien, additional, Huang, Wei-Chun, additional, Cheng, Chin-Chang, additional, Kuo, Shu-Hung, additional, Wang, Wen-Hwa, additional, Ho, Wan-Jing, additional, Hsu, Tsu-Shiu, additional, Mutlu, Bülent, additional, Atas, Halil, additional, Ongen, Gul, additional, Un, Zeynep, additional, Okumus, Gulfer, additional, Hanta, Ismail, additional, Corris, Paul, additional, Peacock, Andrew, additional, Church, Colin, additional, Toshner, Mark, additional, and Newnham, Michael, additional

Published
2021
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