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Hong-Ming Chen,1,2,* Vincent Chin-Hung Chen,1,2,* Han-Pin Hsiao,1 Yi-Ping Weng,1 Ya-Ting Hsu,1 Jun-Cheng Weng,1,3 Jian-An Su,1,2,4 Yi-Lung Chen5,6 1Department of Psychiatry, Chang Gung Medical Foundation, Chiayi Chang Gung Memorial Hospital, Chiayi, Taiwan; 2School of Medicine, Chang Gung University, Taoyuan, Taiwan; 3Department of Medical Imaging and Radiological Sciences, Chang Gung University, Taoyuan, Taiwan; 4Department of Nursing, Chang Gung Institute of Technology, Taoyuan, Taiwan; 5Department of Healthcare Administration, Asia University, Taichung, Taiwan; 6Department of Psychology, Asia University, Taichung, Taiwan*These authors contributed equally to this workCorrespondence: Yi-Lung ChenDepartment of Healthcare Administration, Asia University, 500, Lioufeng Road, Wufeng, Taichung 413, TaiwanTel +886 4 2332 3456 Ext 20106Fax +886 4 2331 6699Email elong@asia.edu.twJian-An SuDepartment of Psychiatry, Chang Gung Medical Foundation, Chiayi Chang Gung Memorial Hospital, No. 6 West Sec., Chia-Pu Road, Puzi City, Chiayi 613, TaiwanTel +886 5 362 1000 Ext 2855Fax +886 5 362 3002Email jian.7715@gmail.comPurpose: Although post-traumatic growth (PTG) and post-traumatic stress symptoms (PTSS) might develop and coexist after a major trauma, few studies have simultaneously examined them in patients with breast cancer. This study investigated the correlation between PTG and PTSS and their differential correlates in patients with breast cancer.Patients and methods: Overall, 145 patients with breast cancer were recruited. PTG and PTSS were assessed using the PTG inventory and the Chinese version of startle, physiological arousal, anger, and numbness, respectively. We investigated the effects of demographics, chemotherapy, depression, family support, alexithymia, and anxiety symptoms on PTG and PTSS. Multivariate linear regression analyses were performed to select the independent correlates of PTSS and PTG.Result: An association was observed between PTG and PTSS (r

Hsiu-Ling Kang,1,* Vincent Chin-Hung Chen,2,3,* Wei-Lin Hung,4 Han-Pin Hsiao,2 Wei-Han Wang4,5 1Department of Nursing, Chang Gung Memorial Hospital, Chiayi, Taiwan; 2Department of Psychiatry, Chang Gung Medical Foundation, Chiayi Chang Gung Memorial Hospital, Taiwan; 3School of Medicine, Chang Gung University, Taoyuan, Taiwan; 4Department of Psychology, Chung Shan Medical University, Taichung, Taiwan; 5Room of Clinical Neuropsychology, Department of Neurology, Chung Shan Medical University Hospital, Taichung, Taiwan *These authors contributed equally to this work Purpose: This cross-sectional pilot study aimed to compare the effects of chemotherapy and targeted therapy on neuropsychological performance and psychiatric symptoms in patients with non-small-cell lung cancer (NSCLC). Patients and methods: A total of 113 patients with NSCLC were recruited. According to their type of cancer treatment, the patients were classified into chemotherapy (n=40), targeted therapy (n=33), and untreated control (n=40) groups. All participants completed five objective tests measuring various domains of cognitive function, a subjective cognitive functioning scale (Functional Assessment of Cancer Therapy–Cognitive Function; FACT-cog), and the Hospital Anxiety and Depression Scale (HADS) either within 6 months after diagnosis (for the untreated group) or about 18 months after treatment. Results: Overall, there were no significant intergroup differences in the proportions of patients with abnormal cognitive performance and psychiatric disturbances. Among the untreated NSCLC patients, 35% had impaired performance in at least one cognitive domain, and a comparable finding (30%–35%) was made for the other two treatment groups. The proportion of patients with impaired psychomotor speed was the highest (10%–15%) across various cognitive domains. Moreover, a significant proportion of NSCLC patients (15%–20%) exhibited HADS-defined anxiety and depression