291 results on '"Hozack WJ"'
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2. Failure of the cement-bone interface. A consequence of strengthening the cement-prosthesis interface?
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Gardiner, RC, primary and Hozack, WJ, additional
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- 1994
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3. Total Hip Arthroplasty After Prior Surgical Treatment of Hip Fracture Is it Always Challenging?
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Mortazavi SM, R Greenky M, Bican O, Kane P, Parvizi J, and Hozack WJ
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- 2012
4. Secondary resurfacing of the patella after primary total knee arthroplasty does the anterior knee pain resolve?
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Parvizi J, Mortazavi SM, Devulapalli C, Hozack WJ, Sharkey PF, Rothman RH, Parvizi, Javad, Mortazavi, S M Javad, Devulapalli, Chaitu, Hozack, William J, Sharkey, Peter F, and Rothman, Richard H
- Abstract
Although it has been shown that the risk of anterior knee pain is greater in patients with nonresurfaced patellae, it is not exactly clear whether the pain would resolve with secondary resurfacing of the patella. Thirty-nine patients (41 knees) underwent secondary patellar resurfacing between January 2001 and January 2007. The mean age was 66 years. The mean body mass index was 29.2 kg/m(2). The average time from primary total knee arthroplasty to resurfacing procedure was 29 months. The mean follow-up was 54 months. Anterior knee pain was the indication for secondary resurfacing in all patients. Although the clinical and functional knee scores improved significantly for whole cohort, 8 patients (8 knees) were dissatisfied with the outcome of surgery. This study highlights that secondary resurfacing is not an always rewarding procedure and patients need to be consulted appropriately with regard to the outcome. [ABSTRACT FROM AUTHOR]
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- 2012
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5. Mark B. Coventry Award: synovial C-reactive protein: a prospective evaluation of a molecular marker for periprosthetic knee joint infection.
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Parvizi J, Jacovides C, Adeli B, Jung KA, Hozack WJ, Parvizi, Javad, Jacovides, Christina, Adeli, Bahar, Jung, Kwang Am, and Hozack, William J
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Background: C-reactive protein (CRP) serum assays are a standard element of the diagnostic workup for periprosthetic joint infection (PJI). However, because CRP is a marker for systemic inflammation, this test is not specific to PJI.Questions/purposes: Our purpose was to assess whether synovial fluid and serum assays alone could differentiate between infected and uninfected revision knee arthroplasties and to determine which of these methods had the greatest diagnostic accuracy.Methods: We collected synovial fluid specimens from 66 patients undergoing revision total knee arthroplasty. Patients were judged uninfected or infected by standardized criteria. Synovial CRP levels were measured using an individual CRP assay (15 samples; 10 infected, five uninfected) and a multiplex immunoassay platform (59 samples; 25 infected, 34 uninfected). Results from preoperative standard serum CRP assays conducted were also collected (55 samples; 25 infected, 30 uninfected). Sensitivity, specificity, and receiver operating characteristic curve analyses were performed for each assay with a diagnosis of infection based on previously established criteria.Results: Synovial CRP concentrations differed between infected and uninfected joints in the multiplex and serum analyses. The area under the curve was 0.84 for the individual assay, 0.91 for the multiplex assay, and 0.88 for the serum CRP assay. Sensitivity and specificity were 70.0% and 100.0% for the individual enzyme-linked immunosorbent assay, 84.0% and 97.1% for the multiplex assay, and 76.0% and 93.3% for the serum CRP assay.Conclusions: An assay measuring CRP in synovial fluid may be more accurate in diagnosing PJI than the standard serum CRP assay. We believe such an assay holds promise as a new diagnostic marker for PJI. [ABSTRACT FROM AUTHOR]- Published
- 2012
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6. Failure following revision total knee arthroplasty: infection is the major cause.
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Mortazavi SM, Molligan J, Austin MS, Purtill JJ, Hozack WJ, Parvizi J, Mortazavi, S M Javad, Molligan, Jeremy, Austin, Matthew S, Purtill, James J, Hozack, William J, and Parvizi, Javad
- Abstract
The objective of this study was to evaluate the survivorship of revision TKA and determine the reasons and predictors for failure. Between January 1999 to December 2005, 499 total knee arthroplasty revisions were performed on 474 patients. There were 292 (61.6%) women and 182 (38.4%) men. The average age at the time of index revision was 63.9 years. Revision was defined as surgery in which at least one component (tibial, patellar, femoral, or polyethylene) required exchange. At an average follow-up of 64.8 months (range, 24.1-111.6), and considering reoperation or re-revision as failure, there were 102 failures (18.3%). Infection was the major cause of failure (44.1%) followed by stiffness (22.6%), patellar or extensor mechanism problems (12.8%), periprosthetic fracture (5.9%), loosening (4.9%), haematoma formation (3.9%), malalignment (2.9%), and instability (2.9%). A total of 83% of failures were early (less than two years). Infection was the most common mechanism of failure of revision TKA. The majority of TKA revision failures tend to occur in the first two years after revision. The mode of failure of revision TKA appears to differ from the failure of primary TKA to some extent. Better understanding of current modes by which TKA revisions fail may enable surgeons to prevent these problems and improve outcomes for revision TKA. [ABSTRACT FROM AUTHOR]
- Published
- 2011
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7. Patient selection for resurfacing hip arthroplasty: a matched case study of resurfacing hip arthroplasty versus total hip arthroplasty.
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Mortazavi SMJ, Fertala K, Restrepo C, Parmar R, and Hozack WJ
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- 2010
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8. Outcomes of posterior stabilized total knee arthroplasty.
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Orozco F and Hozack WJ
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- 2008
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9. Ceramic-on-ceramic total hip arthroplasty early dislocation rate.
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Colwell CW Jr, Hozack WJ, Mesko JW, D'Antonio JA, Bierbaum BE, Capello WN, Jaffe WL, Mai KT, Colwell, Clifford W Jr, Hozack, William J, Mesko, J Wesley, D'Antonio, James A, Bierbaum, Benjamin E, Capello, William N, Jaffe, William L, and Mai, Kenny T
- Abstract
Wear debris from metal-on-polyethylene articulation in conventional total hip arthroplasty can limit the implant's longevity. Modern ceramic material with high wear resistance and low fracture risk has the potential to extend the lifetime of total hip arthroplasty, which makes the procedure potentially more suitable for young, active patients. Concerns with brittle ceramic material include fracture risk, the "squeak" phenomenon, and potentially a higher dislocation rate secondary to limited neck lengths and liner options. We therefore determined the early dislocation rate in modern ceramic-on-ceramic total hip arthroplasty. In 1635 total hip arthroplasties performed over the 9-year period (1996-2005), we observed three anterior and 15 posterior dislocations (1.1%). All were treated successfully, one with a revision and 17 with closed reduction under general anesthesia. Ceramic-on-ceramic total hip arthroplasty can be a good alternative bearing surface with a low dislocation rate. [ABSTRACT FROM AUTHOR]
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- 2007
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10. Revision total hip arthroplasty in octogenarians. A case-control study.
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Parvizi J, Pour AE, Keshavarzi NR, D'Apuzzo M, Sharkey PF, Hozack WJ, Parvizi, Javad, Pour, Aidin Eslam, Keshavarzi, Nahid R, D'Apuzzo, Michele, Sharkey, Peter F, and Hozack, William J
- Abstract
Background: Revision total hip arthroplasty in the very elderly is believed to be associated with a high complication rate. We evaluated the early outcomes and prevalence of complications following revision total hip arthroplasty in patients older than eighty years of age and compared them with those in a younger patient population.Methods: We retrospectively reviewed the results of 170 revision total hip arthroplasties that had been performed in 159 octogenarians in our institute between 1992 and 1999. The mean patient age at the time of surgery was 83.8 years, and the mean follow-up time was 6.8 years. We then compared these results with those of 170 revision total hip arthroplasties, done with the same surgical technique and prosthesis, in 162 patients who were seventy years old or younger and followed for a mean of six years. The functional outcome and the quality of life following the arthroplasties were assessed with use of the Harris hip score and the Short Form-36 (SF-36), respectively. Risk factors for complications and mortality were identified, and Kaplan-Meier analysis was used to determine survivorship.Results: The octogenarians had a significant improvement in the mean Harris hip score, from 47 points preoperatively to 85 points at the time of the latest follow-up. In the control group, the Harris hip score also improved significantly, from a preoperative mean of 44.3 points to a mean of 87.9 points at the time of the latest follow-up. There was no significant difference between the two groups in the magnitude of improvement of the Harris hip score. There were 100 deaths (a rate of 58.8%) at a mean of 5.3 years postoperatively in the octogenarian group compared with twelve deaths (7.1%) in the control group (p < 0.0001). There were no intraoperative deaths in either group. Of the 100 octogenarian patients who died, 94% had a well-functioning hip at the time of death. Perioperative medical complications developed in thirty patients (thirty-eight hips [22.4%]) in the octogenarian group and in twenty-five patients (twenty-six hips [15.3%]) in the control group (p > 0.05). There were thirteen repeat revisions and four other types of reoperations in the octogenarian group and twenty-three repeat revisions and six other types of reoperations in the control group (p = 0.08). A dislocation was sustained by four patients in the octogenarian group and sixteen patients in the control group (p = 0.01).Conclusions: Revision total hip arthroplasty can provide substantial clinical benefit to patients over eighty years of age. The medical complication rate for octogenarians may not differ significantly from that for patients seventy years of age or younger, and the prevalence of technical complications and dislocations can be expected to be lower than that for younger patients. [ABSTRACT FROM AUTHOR]- Published
- 2007
11. Minimally invasive hip arthroplasty: what role does patient preconditioning play?
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Pour AE, Parvizi J, Sharkey PF, Hozack WJ, Rothman RH, Pour, Aidin Eslam, Parvizi, Javad, Sharkey, Peter F, Hozack, William J, and Rothman, Richard H
- Abstract
Background: The benefits of minimally invasive total hip arthroplasty continue to be debated. The objective of this study was to investigate the role of patient education, accelerated rehabilitation, and improved pain control on the outcome of total hip arthroplasty performed through a small incision.Methods: One hundred patients undergoing total hip arthroplasty at our institution were randomized into one of four groups on the basis of the size of the incision, preoperative counseling, the type of preoperative and postoperative rehabilitation, and the analgesia protocol. The operative parameters, complications, time to discharge to home, functional improvement, and patient satisfaction were assessed.Results: The demographic distribution among the four groups was similar. The extent of functional improvement at the time of discharge to home, patient satisfaction, and walking ability at the time of discharge were better in patients who had received an accelerated preoperative and postoperative rehabilitation regimen regardless of the size of the incision. There was no difference in estimated blood loss, mean operative time, transfusion needs, or complications among the groups.Conclusions: This study highlights the importance of factors such as family education, patient preconditioning, preemptive analgesia, and accelerated preoperative and postoperative rehabilitation in influencing the outcome of total hip arthroplasty. The aforementioned factors, and not the surgical technique per se, may play a major role in imparting the better outcome after minimally invasive total hip arthroplasty that has been reported by various investigators. [ABSTRACT FROM AUTHOR]- Published
- 2007
12. Proximal femoral replacement in patients with non-neoplastic conditions.
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Parvizi J, Tarity TD, Slenker N, Wade F, Trappler R, Hozack WJ, Sim FH, Parvizi, Javad, Tarity, T David, Slenker, Nicholas, Wade, Frazier, Trappler, Rachel, Hozack, William J, and Sim, Franklin H
- Abstract
Background: Numerous factors may give rise to the loss of femoral bone stock that can be encountered in revision hip arthroplasty. Proximal femoral replacement is an option for the treatment of severe proximal femoral bone loss. In this study, we sought to determine the outcome of reconstructive surgery with the use of a modular proximal femoral replacement (a so-called megaprosthesis) in patients with proximal femoral bone loss due to non-neoplastic conditions.Methods: A review of computerized databases from two institutions identified forty-eight patients with a mean age of 73.8 years who had undergone the placement of a modular megaprosthesis with or without bone-grafting. The indication for proximal femoral replacement was a periprosthetic fracture in twenty patients, reimplantation because of a deep infection in thirteen, a failed arthroplasty in thirteen, nonunion of an intertrochanteric fracture in one, and radiation-induced osteonecrosis with a subtrochanteric fracture in one. Three patients died before the minimum two-year follow-up interval had elapsed, and two additional patients were lost to follow-up. The mean duration of follow-up for the remaining study group of forty-three patients was 36.5 months.Results: At the time of follow-up, there was a significant improvement in function as measured with the Harris hip score (p < 0.05). The proximal femoral replacement achieved an excellent or good functional outcome in twenty-two of the forty-three hips. The functional outcome was found to be fair in ten hips and poor in the remaining eleven. Ten patients required a reoperation or revision because of at least one complication. With revision used as the end point, the survivorship of the implant was 87% at one year and 73% at five years.Conclusions: Patients with severely compromised bone stock in whom the use of a conventional prosthesis is precluded because of an inability to achieve adequate fixation may be candidates for proximal femoral replacement. Our short-term results suggest that this is a viable salvage procedure for these patients. [ABSTRACT FROM AUTHOR]- Published
- 2007
13. Can epidural anesthesia and warfarin be coadministered?
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Parvizi J, Viscusi ER, Frank HG, Sharkey PF, Hozack WJ, and Rothman RR
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- 2007
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14. Total joint arthroplasty: When do fatal or near-fatal complications occur?
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Parvizi J, Mui A, Purtill JJ, Sharkey PF, Hozack WJ, Rothman RH, Parvizi, Javad, Mui, Alan, Purtill, James J, Sharkey, Peter F, Hozack, William J, and Rothman, Richard H
- Abstract
Background: With the recent trend toward minimally invasive total joint arthroplasty and the increased emphasis on faster recovery and shorter hospital stays, it has become increasingly important to recognize the timing and severity of the various complications associated with elective total joint arthroplasty to ensure that early patient discharge is a safe practice.Methods: We evaluated the systemic and local complications associated with primary unilateral lower-extremity arthroplasties performed during one year in 1636 patients. A total of 966 patients had a primary total hip arthroplasty, and 670 had a primary total knee arthroplasty. All complications that occurred in the hospital and for six weeks following the index surgery were recorded. The circumstances leading to the complications and the details of the therapeutic intervention for each complication were recorded. Analyses were performed to predict the factors that predispose patients to serious complications.Results: One patient (0.06%) in the cohort died during the hospital stay. There were a total of 104 major (life-threatening) complications, including cardiac arrest (one), tachyarrhythmia (thirty-three), pulmonary edema or congestive heart failure (ten), myocardial infarction (six), hypotensive crisis (four), pulmonary embolus (twenty-five), acute renal failure (fourteen), stroke (six), bowel obstruction or perforation (three), and pneumothorax (one). There were seventeen major local complications. Ninety-four (90%) of the major complications occurred within four days after the index surgery. Although older age, increased body mass, and preexistent comorbidities were important predisposing factors for serious medical complications, 58% of the patients who had life-threatening complications develop had no identifiable predisposing factors.Conclusions: This study demonstrated that most of the complications of lower-extremity total joint replacement occur within the time-frame of the typical hospital stay. Given the serious nature of some of these complications and the inability to identify many of the patients who may be at risk, we caution against early discharge of patients from the hospital after elective total joint arthroplasty in the lower extremity. [ABSTRACT FROM AUTHOR]- Published
- 2007
15. In vivo degradation of polyethylene liners after gamma sterilization in air.
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Kurtz SM, Rimnac CM, Hozack WJ, Turner J, Marcolongo M, Goldberg VM, Kraay MJ, Edidin AA, Kurtz, Steven M, Rimnac, Clare M, Hozack, William J, Turner, Joseph, Marcolongo, Michele, Goldberg, Victor M, Kraay, Matthew J, and Edidin, Avram A
- Abstract
Background: Ultra-high molecular weight polyethylene degrades during storage in air following gamma sterilization, but the extent of in vivo degradation remains unclear. The purpose of this study was to quantify the extent to which the mechanical properties and oxidation of conventional polyethylene acetabular liners treated with gamma sterilization in air change in vivo.Methods: Fourteen modular cementless acetabular liners were revised at an average of 10.3 years (range, 5.9 to 13.5 years) after implantation. All liners, which had been machined from GUR 415 resin, had been gamma-sterilized in air; the average shelf life was 0.3 year (range, 0.0 to 0.8 year). After removal, the components were expeditiously frozen to minimize ex vivo changes to the polyethylene prior to characterization. The average duration between freezing and testing was 0.6 year. Mechanical properties and oxidation were measured with use of the small-punch test and Fourier transform infrared spectroscopy, respectively, in the loaded and unloaded regions of the liners.Results: There was substantial regional variation in the mechanical properties and oxidation of the retrieved liners. The ultimate load was observed to vary by >90% near the surface. On the average, the rim and the unloaded bearing showed evidence of severe oxidation near the surface after long-term in vivo aging, but these trends were not typically observed on the loaded bearing surface or near the backside of the liners.Conclusions: The mechanical properties of polyethylene that has been gamma-sterilized in air may decrease substantially in vivo, depending on the location in the liner. The most severe oxidation was observed at the rim, suggesting that the femoral head inhibits access of oxygen-containing body fluids to the bearing surface. This is perhaps why in vivo oxidation has not been associated with clinical performance to date. [ABSTRACT FROM AUTHOR]- Published
- 2005
16. The role of patient restrictions in reducing the prevalence of early dislocation following total hip arthroplasty. A randomized, prospective study.
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Peak EL, Parvizi J, Ciminiello M, Purtill JJ, Sharkey PF, Hozack WJ, Rothman RH, Peak, E Louis, Parvizi, Javad, Ciminiello, Michael, Purtill, James J, Sharkey, Peter F, Hozack, William J, and Rothman, Richard H
- Abstract
Background: It is currently unknown whether functional restrictions following total hip arthroplasty can reduce the prevalence of early postoperative dislocation. Our hypothesis was that dislocation was more likely to occur in patients who were not placed on these restrictions.Methods: We performed a prospective, randomized study to evaluate the role of postoperative functional restrictions on the prevalence of dislocation following uncemented total hip arthroplasty through an anterolateral approach. Of the 630 eligible consecutive patients, 265 patients (303 hips) consented to be randomized into one of two groups (the "restricted" group or the "unrestricted" group). The patients in both groups were asked to limit the range of motion of the hip to <90 degrees of flexion and 45 degrees of external and internal rotation and to avoid adduction for the first six weeks after the procedure. The patients in the restricted group were instructed to comply with additional hip precautions during the first six weeks postoperatively. Specifically, these patients were managed with the placement of an abduction pillow in the operating room before bed transfer and used pillows to maintain abduction while in bed; used elevated toilet seats and elevated chairs in the hospital, in the rehabilitation facility, and at home; and were prevented from sleeping on the side, from driving, and from being a passenger in an automobile. All patients were followed for a minimum of six months postoperatively.Results: There was one dislocation in the entire cohort (prevalence, 0.33%). This dislocation occurred in a patient in the restricted group during transfer from the operating table to a bed with an abduction pillow in place. Patients in the unrestricted group were found to return to side-sleeping sooner (p < 0.001), to ride in automobiles more often (p < 0.026), to drive automobiles more often (p < 0.001), to return to work sooner (p < 0.001), and to have a higher level of satisfaction with the pace of their recovery (p < 0.001) than those in the restricted group. There was an additional expenditure of approximately $655 per patient in the restricted group.Conclusions: Total hip arthroplasty through an anterolateral approach is likely to be associated with a low dislocation rate. Removal of several restrictions did not increase the prevalence of dislocation following primary hip arthroplasty at our institution. However, it did promote substantially lower costs and was associated with a higher level of patient satisfaction as patients achieved a faster return to daily functions in the early postoperative period. [ABSTRACT FROM AUTHOR]- Published
- 2005
17. Treatment protocol for proximal femoral periprosthetic fractures.
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Parvizi J, Rapuri VR, Purtill JJ, Sharkey PF, Rothman RH, Hozack WJ, Parvizi, Javad, Rapuri, Venkat R, Purtill, James J, Sharkey, Peter F, Rothman, Richard H, and Hozack, William J
- Published
- 2004
18. Surgical treatment of limb-length discrepancy following total hip arthroplasty.
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Parvizi J, Sharkey PF, Bissett GA, Rothman RH, Hozack WJ, Parvizi, Javad, Sharkey, Peter F, Bissett, Gina A, Rothman, Richard H, and Hozack, William J
- Abstract
Background: Although most patients with limb-length discrepancy following total hip arthroplasty have manageable symptoms, others may be disabled as a result of pain or functional impairment. In these patients, reoperation may be indicated to equalize the limb lengths. There is a paucity of published data regarding the outcome of surgical intervention to treat this problem. The purpose of the present study was to evaluate the results of revision hip surgery for the treatment of symptomatic limb-length discrepancy.Methods: We retrospectively reviewed the clinical and radiographic records of patients who had undergone revision hip surgery at our institution for the treatment of a symptomatic limb-length discrepancy following a previous total hip arthroplasty. We identified twenty-one patients (twenty-one hips) who had an average age of sixty-six years at the time of revision hip arthroplasty. The average duration of follow-up was 2.8 years, and no patient was lost to follow-up. The indications for revision hip arthroplasty were severe hip and/or back pain for eleven patients, instability of the hip for eight, hip pain and ipsilateral limb paresthesia for one, and hip pain and ipsilateral foot drop for one.Results: Revision arthroplasty was performed at a mean of eight months (range, six days to six years) after primary total hip replacement. The mean limb-length discrepancy at the time of the revision was 4 cm (range, 2 to 7 cm). Following revision arthroplasty, which involved revision of a malpositioned acetabular and/or femoral component, equalization of the limb lengths was achieved in fifteen patients. In the remaining six patients, the mean discrepancy had decreased to 1 cm. The mean Harris hip score improved significantly, from 56.5 points before the revision to 83.2 points at the time of the latest follow-up (p < 0.005). All but two patients were satisfied with the outcome of the revision surgery.Conclusions: Limb-length discrepancy following hip arthroplasty can be associated with pain, paresthesia, and hip instability. In these patients, careful evaluation of the position and orientation of the components may reveal the cause of the discrepancy. Revision arthroplasty may be indicated when a surgically correctable cause of limb-length discrepancy can be identified. [ABSTRACT FROM AUTHOR]- Published
- 2003
19. To our dear friend, dick rothman.
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Hozack WJ, Dorr LD, and Ranawat CS
- Published
- 2012
20. Caution on the use of combined constrained liners and cages in revision total hip arthroplasty.
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Klein GR, Rapuri V, Hozack WJ, Parvizi J, Purtill JJ, Klein, Gregg R, Rapuri, Venkat, Hozack, William J, Parvizi, Javad, and Purtill, James J
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- 2007
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21. New definition for periprosthetic joint infection.
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Hozack WJ and Parvizi J
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- 2011
22. Surgical treatment of limb-length discrepancy following total hip arthroplasty.
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Theruvil B, Kapoor V, Hozack WJ, Parvizi J, Theruvil, Bipin, and Kapoor, Vikas
- Published
- 2004
23. Ten Year Experience With Same Day Discharge Outpatient Total Hip Arthroplasty: Patient Demographics Changed, but Safe Outcomes Were Maintained.
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Ohmori T, Fraval A, and Hozack WJ
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- Humans, Middle Aged, Male, Female, Aged, Adult, Retrospective Studies, Aged, 80 and over, Postoperative Complications epidemiology, Postoperative Complications etiology, Young Adult, Treatment Outcome, Body Mass Index, Age Factors, Arthroplasty, Replacement, Hip statistics & numerical data, Arthroplasty, Replacement, Hip adverse effects, Patient Discharge statistics & numerical data, Patient Readmission statistics & numerical data, Ambulatory Surgical Procedures statistics & numerical data, Ambulatory Surgical Procedures adverse effects
- Abstract
Background: This study aimed to characterize changes in patient demographics and outcomes for same-day discharge total hip arthroplasty (THA) over a 10-year period at a single orthopaedic specialty hospital., Methods: A consecutive series of 1,654 patients between 2013 and 2022 who underwent unilateral THA and were discharged on the same calendar day were retrospectively reviewed. Patient demographics, including age, sex, body mass index (BMI), age-adjusted Charlson Comorbidity Index, and American Society of Anesthesiologists (ASA), were collected. Readmissions, complications, and unplanned visits were recorded for 90 days postoperatively. In order to compare the demographics of patients over time, patients were divided into 3 groups: Time Group A (2013 to 2016), Time Group B (2017 to 2019), and Time Group C (2020 to 2022)., Results: The mean age, BMI, ASA score, and CCI increased significantly across each time group. Age increased from 57 years (range, 23 to 77) to 60 years (range, 20 to 87). The BMI increased from 28.1 (range, 18 to 41) to 29.4 (range, 18 to 47). The percentage of patients aged > 70 years almost doubled over time, as did the percentage of patients who had a BMI > 35. Overall complications increased from 3.44 to 6.82%, reflective of the changing health status of patients. Readmissions increased from 0.57 to 1.70% over time. Despite this, there were no readmissions for any patient within the first 24 hours of surgery., Conclusions: Our study has 3 important findings. We identified a worsening patient demographic over time with an increasing percentage of patients of advanced age and higher BMI, ASA, and age-adjusted Charlson Comorbidity Index. Also, there was also an increase in readmissions, complications, and unplanned visits. In addition, despite this worsening patient demographic, there were no readmissions within 24 hours and a low rate of readmissions or unplanned visits within the first 48 hours across all time periods, suggesting that same-day discharge-THA continues to be safe in properly selected patients., (Copyright © 2024 Elsevier Inc. All rights reserved.)
- Published
- 2024
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24. Vertical or Horizontal (Bikini) Incision for Direct Anterior Total Hip Arthroplasty: Outcomes of Early (<90 day) Revision.
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Zappley NR, Fraval A, Hozack WJ, and Brown SA
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- Humans, Retrospective Studies, Male, Female, Aged, Middle Aged, Treatment Outcome, Aged, 80 and over, Adult, Postoperative Complications etiology, Postoperative Complications epidemiology, Arthroplasty, Replacement, Hip methods, Reoperation statistics & numerical data
- Abstract
Background: The horizontal 'bikini' incision for direct anterior approach (DAA) total hip arthroplasty has gained popularity due to its early wound healing characteristics; however, the nonextensile nature of this approach may pose problems in treating early complications. This study sought to characterize the outcomes of early revision (<90 days) in patients who underwent anterior hip arthroplasty utilizing either a traditional longitudinal incision or a horizontal (bikini) incision., Methods: This retrospective study identified patients who underwent DAA primary total hip arthroplasty with a subsequent DAA revision within 90 days. Patients were divided into two cohorts based on the orientation of their incision: either 'longitudinal incision' (in accordance with the Smith Peterson interval) or 'horizontal bikini incision' (in accordance with the hip flexion crease)., Results: There were 74 patients who underwent DAA revision arthroplasty within 90 days of primary arthroplasty; 65 had a longitudinal incision, and 9 had a horizontal (bikini) incision. In the longitudinal incision group, 2 patients (3.1%) required plastic surgery closure, and 11 patients (16.9%) required additional operations. Of the 9 bikini incision patients, 6 patients required the assistance of plastic surgery closure, and 7 patients required multiple orthopaedic operations., Conclusions: Our study suggests that a horizontal bikini incision is less forgiving in the early postoperative period if a more extensile exposure is needed for revision surgery, as measured by the need for plastic surgery and additional returns to the operating room. In our cohort, the longitudinal incision allowed for the management of early surgical complications with less morbidity., (Copyright © 2024. Published by Elsevier Inc.)
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- 2024
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25. The Efficacy of Preoperative Video-Based Opioid Counseling on Postoperative Opioid Consumption After Total Knee Arthroplasty: A Prospective Randomized Controlled Trial.
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Maheu AR, Hohmann AL, Cozzarelli NF, Khan IA, Hozack WJ, Ilyas AM, and Lonner JH
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- Humans, Male, Female, Prospective Studies, Aged, Middle Aged, Pain Management methods, Pain Measurement, Video Recording, Treatment Outcome, Arthroplasty, Replacement, Knee adverse effects, Pain, Postoperative prevention & control, Pain, Postoperative etiology, Analgesics, Opioid therapeutic use, Analgesics, Opioid administration & dosage, Counseling, Preoperative Care methods, Patient Education as Topic
- Abstract
Background: There are myriad strategies to reduce opioid consumption after total knee arthroplasty (TKA). Recent studies have suggested that preoperative counseling may reduce opioid use after a variety of orthopedic procedures. The purpose of this study was to investigate whether preoperative video-based patient education regarding opioid use and abuse reduces opioid consumption after TKA., Methods: In this prospective randomized controlled trial, patients were randomized before TKA to either receive preoperative video-based counseling or not. Counseling involved a pretaped 5-minute video that educated patients on statistics regarding the "opioid epidemic" and discussed safe use and alternatives to opioids after TKA. There were no significant differences in baseline patient demographics between groups. All patients received a similar multimodal perioperative pain management protocol and completed a daily diary for 2 weeks postoperatively. Diary records measured pain levels using a visual analog score, opioid consumption, side effects experienced, and patient opinion and satisfaction regarding their pain control., Results: Patients in the counseling group consumed significantly less morphine milligram equivalents on postoperative days 0 to 3 (78.8 versus 106.1, P = .020) and in week one postoperatively (129.9 versus 180.7, P = .028), with a trend of less consumption over 2 weeks postoperatively (186.9 versus 239.1, P = .194). There were no significant differences in the number of patients requiring refills, side effects, or daily pain levels between the 2 groups., Conclusions: This study found significantly decreased opioid consumption within the first week after TKA in patients who received preoperative video counseling., (Copyright © 2024 Elsevier Inc. All rights reserved.)
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- 2024
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26. The Use of Iodophor-Impregnated Drapes in Patients With Iodine-Related Allergies: A Case Series and Review of the Literature.
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Fraval A, Zappley N, and Hozack WJ
- Abstract
Background: The use of iodophor-impregnated adhesive drapes have become almost universally incorporated into standard practice of arthroplasty draping technique. Iodine-related allergies in patients planned for joint replacement present a challenge in terms of the best course of action to minimize complications and optimize outcomes., Methods: This is a retrospective case series of patients that received an iodophor-impregnated drape as part of draping for a total hip or knee arthroplasty at a single orthopaedic-specific hospital with documented iodine-related allergies. From 2015 to 2023, 9816 total hip arthroplasty and total knee arthroplasty cases were reviewed, and 135 were documented to have an iodine-related allergy for a prevalence of 1.38%. Intraoperative and postoperative records were reviewed to screen for an allergic reaction or wound healing issues that may have been related to an adverse reaction to the use of the iodophor-impregnated drape., Results: Of the 135 patients, 43 had iodine listed as an allergy, 85 had shellfish, 20 had iodinated contrast media, and 3 had povidone iodine. Sixteen patients had a cluster of iodine-related allergies. There were no intraoperative reports of an allergic reaction to this drape. There were four superficial wound problems, none of which were documented to relate to an allergic dermatitis reaction, and none required further surgery., Conclusions: Patients reporting iodine-related allergies were present in 1.38% of patients undergoing hip or knee arthroplasty in our series. We encountered no allergic reactions or adverse outcomes that could be attributed to the use of iodiphor impregnated drapes in these patients., (© 2023 The Authors.)
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- 2023
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27. Managing the Patient with Peripheral Vascular Disease before Total Knee Arthroplasty Surgery.
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Fraval A and Hozack WJ
- Subjects
- Humans, Risk Factors, Lower Extremity, Wound Healing, Postoperative Complications therapy, Postoperative Complications etiology, Retrospective Studies, Arthroplasty, Replacement, Knee adverse effects, Peripheral Vascular Diseases complications
- Abstract
Peripheral vascular disease (PVD), defined as decreased arterial perfusion to the lower extremities due to atherosclerotic obstruction, is known to occur in patients undergoing total knee arthroplasty with described rates of between 2% and 4.5% PVD is of significance for patients undergoing TKA as it can increase wound healing and infection complications after TKA and is an independent risk factor for arterial complications following TKA. Our goal is to provide a comprehensive review of the pathophysiology of PVD as it relates to TKA, associated outcomes of patients undergoing TKA in the setting of PVD, diagnostic pearls, and current management strategies recommended in the published literature., (Copyright © 2023 Elsevier Inc. All rights reserved.)
- Published
- 2023
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28. Routine Use of Bladder Scans After Primary Total Joint Arthroplasty is Not Necessary: Results of a Protocol Change.
- Author
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Magnuson JA, Hobbs JR, Snyder V, Hozack WJ, Krueger CA, and Austin MS
- Subjects
- Humans, Postoperative Complications epidemiology, Postoperative Complications etiology, Risk Factors, Urinary Bladder diagnostic imaging, Urinary Bladder surgery, Urinary Catheterization adverse effects, Arthroplasty, Replacement, Hip adverse effects, Arthroplasty, Replacement, Knee adverse effects, Urinary Retention epidemiology, Urinary Retention etiology
- Abstract
Background: Postoperative urinary retention is a common concern after total joint arthroplasty (TJA) and can cause discomfort, incontinence and, if left untreated, myogenic changes to the bladder. However, overdiagnosis of postoperative urinary retention by bladder scans may lead to unnecessary interventions and delayed discharges. The purpose of this study was to compare the safety of two bladder management protocols following TJA., Methods: From January 3, 2022 to April 29, 2022, 519 consecutive patients operated on by thirteen surgeons underwent routine postoperative bladder scanning (standard protocol). From February 28, 2022 to April 29, 2022, a new protocol was introduced by three surgeons in 209 consecutive patients using a specific algorithm (selective protocol) so that only symptomatic patients had bladder scans. The primary outcome of interest was catheterization rate. Chi-square and Students t-tests were used for analyses. There were 37.7% of patients in the selective group who received scans., Results: Times to catheterization, readmissions, emergency department visits, and straight catheterization rates (15.0 versus 14.8% P = .999) were similar. More scans in the selective group resulted in intervention (39.2 versus 15.0%, P < .001). Prevoid volumes were higher in the selective protocol (608 versus 448 mL, P < .001). Postvoid volumes were similar (233 versus 223 mL, P = .497). There was one readmission for a urinary tract infection in the standard group and no urinary-related readmissions in the selective group., Conclusion: The selective protocol had a higher rate of same day discharge, fewer bladder scans, and did not lead to increased rates of urinary-related complications. These findings suggest that selective bladder scanning for symptomatic patients can be safely instituted for TJA patients., (Copyright © 2023 Elsevier Inc. All rights reserved.)
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- 2023
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29. Dislocation risk after robotic arm-assisted total hip arthroplasty: a comparison of anterior, lateral and posterolateral approaches.
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Marcovigi A, Sandoni D, Ciampalini L, Perazzini P, Zambianchi F, Hozack WJ, and Catani F
- Subjects
- Humans, Acetabulum surgery, Treatment Outcome, Arthroplasty, Replacement, Hip adverse effects, Arthroplasty, Replacement, Hip methods, Robotic Surgical Procedures adverse effects, Hip Prosthesis adverse effects, Joint Dislocations surgery
- Abstract
Aims: Dislocation is a major cause of early failure after THA and is highly influenced by surgical approach and component positioning. Robotic-arm assisted arthroplasty has been developed in an attempt to improve component positioning and reduce postoperative complications.The purpose of this study was to compare the rate of dislocation after robotic total hip arthroplasty through 3 different surgical approaches., Materials and Methods: All patients who had undergone robotic arm-assisted THA at 3 centres between 2014 and 2019 were reviewed. After applying exclusion criteria, 1059 patients were included in the study. An anterior approach was used in 323 patients, a lateral approach in 394 and a posterior approach in 342 patients.Episodes of dislocation were recorded after 6 months follow-up. Stem anteversion, cup anteversion, cup inclination and combined anteversion were collected using the integrated navigation system.Cumulative incidence (CI), incidence rate (IR) and risk ratio (RR) were calculated with a confidence interval of 95%., Results: 3 cases of dislocation (2 posterior approach, 1 anterior approach) were recorded, with a dislocation rate of 0.28% and an IR of 0.14%.The rate of placement of the cup in the Lewinnek safe zone was 82.2% for the posterior approach, 82.0% for the lateral approach and 95.4% for the anterior approach.The rate of placement in the combined version safe zone was 98.0% for the posterior approach, 73.0% for the lateral approach and 47.1% for the anterior approach.The incidence rate of dislocation was 0.30% for the anterior approach, 0.34% for the posterior approach and 0% for the lateral approach., Conclusions: The robotic arm-assisted technique is associated with a low risk of dislocation. The combined version technique appears to be a reliable way to reduce the risk of dislocation through the posterolateral approach but does not appear to be essential when using the lateral and anterior approaches.
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- 2023
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30. Commentary on "Low Molecular Weight Heparin is Superior to Aspirin in the Prevention of Thromboembolic Disease, or is It? Response to an Editorial".
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Parvizi J, DeMik DE, Hozack WJ, Dunbar MJ, Mont MA, and Lachiewicz PA
- Subjects
- Humans, Aspirin, Anticoagulants, Heparin, Low-Molecular-Weight, Thromboembolism prevention & control
- Published
- 2023
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31. Direct anterior versus direct lateral hip approach in total hip arthroplasty with the same perioperative protocols one year post fellowship training.
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Makhdom AM and Hozack WJ
- Subjects
- Humans, Retrospective Studies, Fellowships and Scholarships, Length of Stay, Treatment Outcome, Arthroplasty, Replacement, Hip methods
- Abstract
Background: Variable results have been reported regarding the clinical outcomes in Total hip arthroplasty (THA) based on the surgical approach. The aim of this study is to compare the clinical outcomes between Direct anterior (DA) and direct lateral (DL) approaches in THA when performed immediately after fellowship training., Methods: During the 1st year of practice, all consecutive patients who underwent THA via DA and DL hip approaches were retrospectively investigated. Patients'demographics, diagnosis, American society of Anesthesiology (ASA) score, route of anesthesia, length of hospital stay (LOS), leg length discrepancy (LLD), radiographic parameters, operative time, number of opioids refills postoperatively, and complications were collected and compared between the two groups. The short form of Hip Disability and Osteoarthritis Outcome score, Joint Replacement (HOOS, JR) was prospectively collected pre and postoperatively. The minimum follow-up period was 2 years., Results: Forty patients in DA group and 38 patients in DL group were included. No statistically significant difference was found between the two groups in terms of demographics, diagnosis, ASA scores, route of anesthesia at the time of THA, postoperative radiographic parameters, LOS, LLD, opioid refills and HOOS scores (p > 0.05). Patients in the DA group had shorter operative time (83 ± 17 min) when compared to the DL group (93 ± 24 min) (p = 0.03). No major complications were found except for one early deep infection patient in DL group., Conclusion: Both DA and DL approaches resulted in satisfactory outcomes in THA when performed by a fellowship trained surgeon., (© 2023. The Author(s).)
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- 2023
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32. The Ability of Robot-Assisted Total Knee Arthroplasty in Matching the Efficiency of Its Conventional Counterpart at an Orthopaedic Specialty Hospital.
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Meghpara MM, Goh GS, Magnuson JA, Hozack WJ, Courtney PM, and Krueger CA
- Subjects
- Humans, Learning Curve, Operative Time, Hospitals, Knee Joint surgery, Arthroplasty, Replacement, Knee, Robotics, Robotic Surgical Procedures
- Abstract
Background: Robot-assisted total knee arthroplasty (RA-TKA) has become a popular technology. Studies have investigated the learning curve for surgeons incorporating RA-TKA into practice, but less is known regarding the change in operative efficiency when introducing RA-TKA into a facility. The purpose of this study was to investigate the effects of RA-TKA on operative and turnover time at an orthopaedic specialty hospital., Methods: A total of 148 cases (74 RA-TKA and 74 conventional TKA [C-TKA]) performed by 2 surgeons with previous robotic experience were identified following the introduction of RA-TKA at our facility. Patient demographics, comorbidities, and operative times (ie, wheels-in to incision, incision to closure, closure to wheels-out, and turnover time) were recorded. Cumulative summation analyses were used to investigate learning curves of factors extraneous to surgeon proficiency with RA-TKA., Results: While RA-TKA had a slightly longer set up (3 minutes; range, 12-45), surgical (5 minutes; range, 33-118), and breakdown time (3 minutes; range, 2-7), there was no difference in turnover time between the groups. The learning curve for surgeon A was 6 robotic cases, whereas surgeon B demonstrated no learning curve. There was no identifiable learning curve for turnover time., Conclusion: There was a mean of 8 minutes of increased time required to perform a RA-TKA compared to C-TKA. However, these small increases for the RA-TKA group for set-up, surgical, and breakdown times are not likely to be clinically relevant compared to the C-TKA. It appears that the RA-TKA technology was able to be incorporated into this specialty hospital with minimal changes to surgical efficiency., (Copyright © 2022 Elsevier Inc. All rights reserved.)
- Published
- 2023
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33. Low-Molecular-Weight Heparin Is Superior to Aspirin in the Prevention of Thromboembolic Disease: Or Is It?
- Author
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Parvizi J, DeMik DE, Hozack WJ, Dunbar MJ, Mont MA, and Lachiewicz PF
- Subjects
- Humans, Aspirin therapeutic use, Anticoagulants therapeutic use, Heparin, Heparin, Low-Molecular-Weight therapeutic use, Thromboembolism etiology, Thromboembolism prevention & control
- Published
- 2023
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34. Low-Molecular-Weight Heparin Is Superior to Aspirin in the Prevention of Thromboembolic Disease: Or Is It?
- Author
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Parvizi J, DeMik DE, Dunbar M, Hozack WJ, Mont MA, and Lachiewicz PF
- Subjects
- Humans, Aspirin therapeutic use, Heparin, Low-Molecular-Weight therapeutic use, Thromboembolism
- Abstract
Competing Interests: Disclosure: The Disclosure of Potential Conflicts of Interest forms are provided with the online version of the article (http://links.lww.com/JBJS/H261).
- Published
- 2022
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35. Return to Work and Driving After Robotic Arm-Assisted Total Knee Arthroplasty.
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Bhowmik-Stoker M, Mathew KK, Chen Z, Chen AF, Hozack WJ, Mahoney O, Orozco FR, and Mont MA
- Abstract
Background: Robotic arm-assisted total knee arthroplasty (RATKA) has demonstrated improved patient-reported outcome measures. Less evidence has been reported on how frequently patients return to complex activities of daily living. Our purposes were to investigate (1) hospital lengths of stay (LOSs) (2) discharge dispositions and (3) the rates and postoperative time intervals at which patients returned to driving and working., Methods: A total of 50 RATKA patients who were employed prior to surgery were included. Outcomes included hospital LOS, discharge dispositions, return to driving, and return to work., Results: A total of 48 patients (96%) were discharged home with self-care or health aid discharge after a mean LOS of 1.2 ± 0.6 days. Twelve patients (24%) returned to driving within 3 weeks of surgery. In our study, 100% of patients who underwent RATKA returned to driving after a mean of 29 days (range, 4 to 62 days). Forty-five patients (90%) returned to their preoperative level of work after a mean of 46 days (range, 2 to 96 days). Nineteen patients (38%) returned to work within 3 weeks., Conclusions: This study showed fast recovery after RATKA, with >90% returning to driving and working at full capacity within 2 months. Many (38%) returned to work within 3 weeks. Further studies to demonstrate the value of RATKA with respect to recovery of complex activities are needed. Compared to controls from previously published literature on manual total knee arthroplasties, it appears that patients who undergo RATKA have similar or better outcomes in reference to return to driving., (© 2022 The Authors.)
- Published
- 2022
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36. Total Joint Arthroplasty at a Novel "Hyperspecialty" Ambulatory Surgical Center With Extended Care Suites is as Safe as Inpatient Arthroplasty.
- Author
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Goh GS, D'Amore T, Courtney PM, Hozack WJ, and Krueger CA
- Abstract
Background: New "hyperspecialty" ambulatory surgical centers (HASCs) have been introduced to deliver safe and cost-efficient care, allowing patients to spend additional nights in an extended care suite before discharge. This study compared the 90-day complications and readmissions of total joint arthroplasty (TJA) at an HASC and inpatient TJA at a tertiary hospital., Methods: We retrospectively reviewed 1365 primary, unilateral, TJAs (658 total hip arthroplasty, 707 total knee arthroplasty) performed at 4 HASCs in 2017-2021. Following their outpatient procedure, patients were discharged to an extended care suite staffed full-time by nurses and physical therapists. These patients were matched 1:1 with 1365 inpatient TJAs (628 total hip arthroplasty, 737 total knee arthroplasty) based on demographics, joint, and American Society of Anesthesiologists (ASA) score. Ninety-day complications and readmissions were compared., Results: The mean age was 60.0 ± 9.8 years and 59.4 ± 8.1 years in the inpatient and outpatient groups, respectively ( P = .106). There was no difference in ASA≥3 patients (16.4% vs 17.7%; P = .387) and operative time (86.9 ± 31.8 vs 88.7 ± 27.9 minutes; P = .118). Five patients (0.4%) in the outpatient group were transferred to an acute hospital. When comparing 90-day outcomes between the inpatient and outpatient groups, there was no difference in pulmonary embolism (0.1% vs 0.0%; P = .317), mechanical complications (0.3% vs 0.7%; P = .165), periprosthetic joint infections (0.5% vs 1.1%; P = .092), or readmissions (1.2% vs 1.5%; P = .513). A subgroup analysis of ASA≥3 patients yielded similar findings., Conclusions: Patients undergoing outpatient TJA at a novel HASC had similar complication and readmission rates as those undergoing TJA at a tertiary hospital. Based on these data, such facilities seem appropriate for the care of outpatient TJA patients with ASA<4., (© 2022 The Authors.)
- Published
- 2022
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37. Minimum Five-Year Outcomes of Modular Dual Mobility in Primary Total Hip Arthroplasty.
- Author
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Baker CM, Restrepo C, and Hozack WJ
- Subjects
- Female, Hip Joint surgery, Humans, Prosthesis Design, Prosthesis Failure, Reoperation, Retrospective Studies, Arthroplasty, Replacement, Hip, Hip Prosthesis
- Abstract
Background: Using a modular dual-mobility (MDM) bearing in primary total hip arthroplasty (THA) has not been widely evaluated. The purpose of this study is to evaluate clinical outcomes and survivorship following MDM bearings in primary THA., Methods: We used our registry database for patients with an MDM bearing on primary THA, performed by 6 surgeons through supine direct lateral or direct anterior approach. MDM bearings were used most often when impingement or subluxation was present intraoperatively despite proper component position. Another indication was a patient with planned activities who might be at a higher risk of instability postoperatively., Results: A total of 127 MDM bearings were used in primary THA in 119 patients. Mean follow-up was 6.77 years (range 5-8.9). Five hips were revised, none of which were due to MDM bearing failure. Preoperative Hip dysfunction and Osteoarthritis Outcome Score for Joint Replacement, Veterans RAND/Short Form 12 Physical Health Score and Mental Health Score increased from 25.81 to 52.40 (P < .0001), 30.42 to 44.50 (P < .0001), and 36.21 to 52.70 (P < .0001) at latest completed survey follow-up, respectively., Conclusion: This MDM bearing shows excellent functional outcomes at a minimum 5 years of follow-up with no bearing-related failures. It can be an excellent choice in primary THA specifically in females where the use of increased head size to prevent instability is not possible due to anatomical restrictions and liner thickness., (Copyright © 2022 Elsevier Inc. All rights reserved.)
- Published
- 2022
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38. Short-Term Outcomes Are Comparable between Robotic-Arm Assisted and Traditional Total Knee Arthroplasty.
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Grosso MJ, Li WT, Hozack WJ, Sherman M, Parvizi J, and Courtney PM
- Subjects
- Humans, Patient Discharge, Reoperation, Retrospective Studies, Arthroplasty, Replacement, Knee adverse effects, Robotic Surgical Procedures adverse effects
- Abstract
Robotic-arm assisted total knee arthroplasty (rTKA) was developed to provide for increased accuracy of component placement compared with conventional manual TKA (mTKA). Whether or not rTKA is cost-effective in a bundled payment model has yet to be addressed. The purpose of this comparative study was to evaluate the short-term clinical outcomes of rTKA and mTKA. We retrospectively reviewed a series of 4,086 consecutive primary TKA performed by one of five surgeons across six different hospitals at our institution from January 2016 to December 2018. Outcomes for rTKA cases ( n = 581) and mTKA cases ( n = 3,505) were compared using unmatched multivariate analysis and a matched cohort. We analyzed 90-day outcomes, episode-of-care claims data, and short form (SF-12) outcome scores to 2 years postoperatively. In matched bivariate analysis, there was no difference in episode-of-care costs, postacute care costs, complications, 90-day readmission rates, emergency department/urgent care visits, reoperations, and mortality between rTKA and mTKA patients ( p > 0.05). Matched patients undergoing rTKA did have a shorter hospital length of stay (1.46 vs. 1.80 days, p < 0.001) and decreased rates of discharge to rehabilitation facilities (5.5 vs. 14.8%, p < 0.001). SF-12 scores were clinically similar. Multivariate analysis demonstrated no differences in any 90-day outcome. We conclude that patients undergoing rTKA have comparable costs, 90-day outcomes, and clinically similar improvements in functional outcome scores compared with mTKA patients. Further study is needed to determine whether rTKA will result in improved implant survivorship and long-term functional outcomes (Level of evidence III)., Competing Interests: P.M.C. reports personal fees from ConvaTec, Hip Innovation Technology, and Journal of Bone and Joint Surgery outside the submitted work. W.J.H. reports other from Journal of Arthroplasty, personal fees and other from Stryker outside the submitted work. The rest authors declare no conflict of interest., (Thieme. All rights reserved.)
- Published
- 2022
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39. Clinical and Radiographic Outcomes of Novel 3D-Printed Highly Porous Knee Cone Design.
- Author
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Tarabichi S, Grau L, Arshi A, Post Z, Ong A, and Hozack WJ
- Abstract
Introduction: Metaphyseal bone defects seen at revision total knee replacement (TKA) have traditionally been treated with bone graft or cement. Recently, metal augments have surfaced as viable alternatives to conventional methods previously used in these patients. Newer 3D-printed metal cones offer better biological fixation as a means of improving construct stability. This study aimed to determine clinical and radiographic outcomes of the novel 3D-printed titanium cone augments for femoral and tibial metaphyseal bone defects., Materials and Methods: A retrospective review was undertaken of 72 patients who underwent revision TKA with metaphyseal cones (Stryker) and stemmed implants from 2015-2017. Knee Injury and Osteoarthritis Outcome Scores (KOOS Jr) and VR/SF-12 scores were recorded. Knee Society radiographic scores were calculated at latest follow up to evaluate for radiolucency and biological fixation. Loosening noted on radiographs and reoperation for any reason were the endpoints to determine survivorship., Results: A total of 68 patients with 78 cones (58 tibial, 20 femoral) met inclusion criteria. Mean follow up was 3.4 years (range 2-5.4 years). The average KOOS Jr score increased from 38 preoperatively to 66 at two years. The average VR/SF-12 PH score increased from 33 preoperatively to 37 at two years. The average VR/SF-12 MH score increased from 46 preoperatively to 54 at two years. Twelve percent of tibial implants and 10% of femoral implants with cones were found to have lucency in at least one radiographic zone. Overall survivorship at latest follow up was 93% with two patients requiring revision for infection, two revised following mechanical complications, and one patient who underwent polyethylene exchange after experiencing mechanical complications. When considering only aseptic loosening, survivorship was 100%., Conclusion: This 3D-printed titanium femoral and tibial cone augment system showed excellent survivorship, biological fixation, clinical outcomes, and radiographic outcomes in the setting of TKA. Further studies are needed for assessment of long-term survivorship.
- Published
- 2022
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40. Stability in Direct Lateral vs Direct Anterior Total Hip Arthroplasty in the Context of Lumbar Spinal Fusion.
- Author
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Goyal DKC, Divi SN, Vaccaro AR, and Hozack WJ
- Subjects
- Humans, Lumbar Vertebrae surgery, Retrospective Studies, Arthroplasty, Replacement, Hip, Hip Dislocation surgery, Spinal Fusion adverse effects
- Abstract
Introduction: Lumbar spinal fusion (LSF) may increase the risk of dislocation in patients who have undergone total hip arthroplasty (THA), especially when the LSF was done before the THA. Most publications evaluated patients who had undergone THA using a posterior approach to the hip, yet there are little data on the influence of other surgical approaches. The goal of this study was to evaluate the risk of THA dislocation with anterior supine-based surgical approaches to the hip in patients who have undergone surgical management of concurrent hip and spine pathology., Methods: Patients older than 18 years who underwent an LSF and THA using a supine approach-either direct anterior (DA) or direct lateral (DL)-between 2000 and 2018 were identified. Only standard bearings (28-32-36-40 mm) were used. The dislocation rate was determined in this cohort. A subsequent analysis was conducted, stratifying patients based on the order in which they received the LSF or THA., Results: A total of 582 surgical hip-spine patients were retrospectively identified and included in the cohort. Of total, 332 patients (57.0%) received an LSF before the THA; 250 (43.0%) had the fusion after a primary hip replacement. There were 143 patients (24.6%) in the DA group and 439 (75.4%) in the DL group. Overall, there were five dislocations (0.9%) in the entire cohort., Conclusions: In patients with simultaneous degenerative hip and lumbar spine pathology, anterior supine-based approaches demonstrate a low (<1%) risk of instability. Given the small number of total dislocation events (n = 5), additional analysis is warranted to assess the effect of different anterior approaches (DA versus DL) or timing of lumbar spinal surgery (before or after THA)., Level of Evidence: Level III., (Copyright © 2022 by the American Academy of Orthopaedic Surgeons.)
- Published
- 2022
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41. Cemented Versus Cementless Total Knee Arthroplasty in Obese Patients With Body Mass Index ≥35 kg/m 2 : A Contemporary Analysis of 812 Patients.
- Author
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Goh GS, Fillingham YA, Sutton RM, Small I, Courtney PM, and Hozack WJ
- Subjects
- Body Mass Index, Bone Cements, Humans, Obesity complications, Prosthesis Failure, Reoperation, Treatment Outcome, Arthroplasty, Replacement, Knee, Knee Injuries, Knee Prosthesis, Osteoarthritis
- Abstract
Background: Cemented total knee arthroplasty (TKA) has been shown to have higher failure rates in obese patients, and cementless TKA may provide more durable fixation. This study compared outcomes and survivorship of obese patients undergoing cemented and cementless TKA of the same modern design., Methods: We identified a consecutive series of 406 primary cementless TKA performed in obese patients with body mass index (BMI) ≥35 kg/m
2 in 2013-2018. Each case was matched 1:1 with 406 cemented TKA based on age, sex, BMI, bearing surface, and year of surgery. Knee Injury and Osteoarthritis Outcome Score for Joint Replacement and Short Form-12 were collected preoperatively, at 6 months and 2 years. Implant survivorship was recorded at mean 4.0 years (range 2.0-7.8)., Results: There was no difference in mean BMI between the cemented (38.6 ± 3.4 kg/m2 ; range, 35-60) and cementless cohorts (38.7 ± 3.3 kg/m2 ; range, 35-54; P = .706). Both groups had similar final postoperative scores and improvement in scores at 2 years. Furthermore, a similar percentage met the minimal clinically important difference (Knee Injury and Osteoarthritis Outcome Score for Joint Replacement, 70.0% vs 71.2%, P = .700; Short Form-12 Physical, 74.1% vs 70.4%, P = .240). Both groups demonstrated high 7-year survivorship free from aseptic revision (99.0% vs 99.5%, P = .665)., Conclusion: Obese patients with BMI ≥35 kg/m2 undergoing cementless and cemented TKA of the same modern design had similar outcomes and survivorship at early to mid-term follow-up. Continued surveillance of this high-risk population is necessary., (Copyright © 2022 Elsevier Inc. All rights reserved.)- Published
- 2022
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42. Redefining Indications for Modern Cementless Total Knee Arthroplasty: Clinical Outcomes and Survivorship in Patients >75 Years Old.
- Author
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Goh GS, Fillingham YA, Ong CB, Krueger CA, Courtney PM, and Hozack WJ
- Subjects
- Aged, Aged, 80 and over, Bone Cements, Humans, Prosthesis Failure, Reoperation, Survivorship, Treatment Outcome, Arthroplasty, Replacement, Knee adverse effects, Knee Prosthesis
- Abstract
Background: Most studies on cementless total knee arthroplasty (TKA) have excluded patients >75 years due to concerns that older patients have poorer bone mineral density and osteogenic activity. This study compared the midterm outcomes and survivorship of cemented and cementless TKA of the same modern design performed in patients >75 years., Methods: We identified a consecutive series of 120 primary cementless TKA performed in patients >75 years. Each case was propensity score matched 1:3 with 360 cemented TKA of the same modern design based on age, sex, body mass index, Charlson Comorbidity Index, bilateral procedures, liner type, and year of surgery. Knee Injury and Osteoarthritis Outcome Score for Joint Replacement (KOOS-JR) and Short Form-12 (SF-12) were collected preoperatively, at 6 months and 2 years. Implant survivorship was recorded at mean 4.2 years (range, 2.0-7.9)., Results: Mean age was 79.0 ± 3.4 years (range, 75-92) in the cemented cohort and 78.9 ± 3.5 (range, 75-91) in the cementless cohort (P = .769). There was no difference in final postoperative scores or improvement in scores at 2 years. The percentage of patients that met the minimal clinically important difference was also similar (KOOS-JR, 68.9% vs 69.2%, P = .955; SF-12 Physical, 71.7% vs 66.7%, P = .299). Seven-year survivorship free from aseptic revision was 99.4% for cemented knees and 100% for cementless knees (log-rank, P = .453)., Conclusion: Patients over 75 years undergoing cementless or cemented TKA of the same modern design had comparable outcomes and survivorship in the midterm. The theoretical risks of cementless fixation in this age group were not realized in this study., (Copyright © 2021 Elsevier Inc. All rights reserved.)
- Published
- 2022
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43. Emergency Department Visits After Total Joint Arthroplasty for Concern for Deep Vein Thromboses.
- Author
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Grosso MJ, Chisari E, Vannello C, and Hozack WJ
- Subjects
- Emergency Service, Hospital, Humans, Postoperative Complications, Retrospective Studies, Ultrasonography, Arthroplasty, Replacement, Hip adverse effects, Arthroplasty, Replacement, Knee adverse effects, Venous Thrombosis epidemiology, Venous Thrombosis etiology
- Abstract
Background: Concern for deep vein thrombosis (DVT) is the most common reason for emergency department (ED) referral after total joint arthroplasty (TJA) at our institution. We aim to investigate the referral pathway, together with the cost and outcomes associated with patients who access an ED because of concern for DVT after TJA., Methods: We reviewed a consecutive series of all primary hip and knee arthroplasty patients who accessed the ED for concern for DVT within 90 days of surgery over a one-year period. The referral source and costs associated with the ED visit were collected. A propensity-matched control cohort (n = 252) that was not referred to the ED for DVT was used to compare patient-reported outcomes measures., Results: In 2018, 108/10,445 primary TJA patients (1.0%) accessed the ED for concern about DVT. The most common reason for accessing the ED was self-referral (69, 64%), followed by orthopaedic on-call referral (21, 19%). Only 15 patients (14%) were found to have ultrasonography evidence of DVT. The mean cost for accessing the ED for DVT for patients with public insurance was $834 (range $394-$2,877). When compared with the control cohort, patients who accessed the ED for DVT had significantly lower postoperative functionality scores (52.5 versus 65.9, P < 0.001)., Discussion: At our institution, 1% of patients who undergo primary TJA accessed the ED for concern for DVT at substantial cost, with only a small portion testing positive for DVT. Self-referral is by far the most common pathway. Additional investigations will be aimed at determining better pathways for DVT work-up, while ensuring appropriate management., (Copyright © 2021 by the American Academy of Orthopaedic Surgeons.)
- Published
- 2021
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44. Outcomes of simultaneous bilateral total hip arthroplasty for 256 selected patients in a single surgeon's practice.
- Author
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Inoue D, Grace TR, Restrepo C, and Hozack WJ
- Subjects
- Adult, Aged, Aged, 80 and over, Female, Hip Prosthesis, Humans, Length of Stay statistics & numerical data, Male, Middle Aged, Patient Discharge statistics & numerical data, Patient Positioning, Patient Readmission statistics & numerical data, Postoperative Complications epidemiology, Arthroplasty, Replacement, Hip methods, Patient Selection
- Abstract
Aims: Total hip arthroplasty (THA) using the direct anterior approach (DAA) is undertaken with the patient in the supine position, creating an opportunity to replace both hips under one anaesthetic. Few studies have reported simultaneous bilateral DAA-THA. The aim of this study was to characterize a cohort of patients selected for this technique by a single, high-volume arthroplasty surgeon and to investigate their early postoperative clinical outcomes., Methods: Using an institutional database, we reviewed 643 patients who underwent bilateral DAA-THA by a single surgeon between 1 January 2010 and 31 December 2018. The demographic characteristics of the 256 patients (39.8%) who underwent simultaneous bilateral DAA-THA were compared with the 387 patients (60.2%) who underwent staged THA during the same period of time. We then reviewed the length of stay, rate of discharge home, 90-day complications, and readmissions for the simultaneous bilateral group., Results: Patients undergoing simultaneous bilateral DAA-THA had a 3.5% transfusion rate, a 1.8 day mean length of stay, a 98.1% rate of discharge home, and low rates of 90-day infection (0.39%), dislocation (0.39%), periprosthetic fracture (0.77%), venous thromboembolism (0%), haematoma (0.39%), further surgery (0.77%), and readmission (0.77%). These patients were significantly younger (mean 58.2 years vs 62.5 years; p < 0.001), more likely to be male (60.3% vs 46.5%; p < 0.001), and with a trend towards having a lower mean BMI (27.8 kg/m
2 vs 28.4 kg/m2 ; p = 0.071) than patients who underwent staged bilateral DAA-THA., Conclusion: Patients selected for simultaneous bilateral DAA-THA in a single surgeon's practice had a 3% rate of postoperative transfusion and a low rate of complications, readmissions, and discharge to a rehabilitation facility. Simultaneous bilateral DAA-THA appears to be a reasonable and safe form of treatment for patients with bilateral symptomatic osteoarthritis of the hip when undertaken by an experienced arthroplasty surgeon with appropriate selection criteria. Cite this article: Bone Joint J 2021;103-B(7 Supple B):116-121.- Published
- 2021
- Full Text
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45. Survivorship, Clinical and Radiographic Outcomes of a Novel Cementless Metal-Backed Patella Design.
- Author
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Grau LC, Ong AC, Restrepo S, Griffiths SZ, Hozack WJ, and Smith EB
- Subjects
- Follow-Up Studies, Humans, Patella diagnostic imaging, Patella surgery, Prosthesis Design, Prosthesis Failure, Reoperation, Survivorship, Treatment Outcome, Arthroplasty, Replacement, Knee, Knee Prosthesis
- Abstract
Background: Enhanced implant longevity through biological fixation is achievable using cementless total knee arthroplasty but concerns about patellar component failure have lingered because of prior experiences with older component designs. A new metal-backed patella (MBP) design was released which features a 3-dimensional printed porous titanium metal backing to improve biologic fixation potential and a unique compression molding technique to create a stronger interlock layer between the polyethylene and metal backing. Our study purpose was to determine the clinical and radiographic outcomes and survivorship of this novel cementless MBP., Methods: Our institutional registry identified 388 cementless MBP with minimum 2-year and 80 with minimum 5-year follow-up. Knee Injury and Osteoarthritis Outcome Score for Joint Replacement and 12-item Veterans RAND/Short Form Health Survey (VR/SF-12) scores were used to evaluate clinical outcomes. Aseptic loosening noted on radiographs as well as revision for any reason were the end points used to determine survivorship., Results: Improvement in the preoperative Knee Injury and Osteoarthritis Outcome Score for Joint Replacement, VR/SF-12 physical health and mental health scores were all statistically significant at 2-year follow-up and the VR/SF-12 mental health score at 5-year follow-up. By radiologic criteria, biologic fixation of the patellar component was present in all except 1 case at 2 years (99.6%) and at 5 years (97.7%). Radiolucent lines were present in 15 cases (6.2%) at 2 years and in 6 cases (14%) at 5 years, but progressive increase in radiolucent lines was seen in only 4 cases. No component was revised for loosening; aseptic survivorship was 100%., Conclusion: This 3-dimensional printed cementless patellar component shows excellent survivorship at 2-year and 5-year follow-up. We are hopeful about the long-term durability of this implant., (Copyright © 2021 Elsevier Inc. All rights reserved.)
- Published
- 2021
- Full Text
- View/download PDF
46. Excellent mid-term follow-up for a new 3D-printed cementless total knee arthroplasty.
- Author
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Restrepo S, Smith EB, and Hozack WJ
- Subjects
- Aged, Female, Follow-Up Studies, Humans, Male, Middle Aged, Prosthesis Failure, Registries, Reoperation statistics & numerical data, Titanium, Arthroplasty, Replacement, Knee methods, Knee Prosthesis, Printing, Three-Dimensional, Prosthesis Design
- Abstract
Aims: Cementless total knee arthroplasty (TKA) offers the potential for strong biological fixation compared with cemented TKA where fixation is achieved by the mechanical integration of the cement. Few mid-term results are available for newer cementless TKA designs, which have used additive manufacturing (3D printing). The aim of this study was to present mid-term clinical outcomes and implant survivorship of the cementless Stryker Triathlon Tritanium TKA., Methods: This was a single institution registry review of prospectively gathered data from 341 cementless Triathlon Tritanium TKAs at four to 6.8 years follow-up. Outcomes were determined by comparing pre- and postoperative Knee Injury and Osteoarthritis Outcome Score for Joint Replacement (KOOS JR) scores, and pre- and postoperative 12-item Veterans RAND/Short Form Health Survey (VR/SF-12) scores. Aseptic loosening and revision for any reason were the endpoints which were used to determine survivorship at five years., Results: At mid-term follow-up, the mean KOOS JR score improved significantly from 33.14 (0 t0 85, standard deviation (SD) 21.88) preoperatively to 84.12 (15.94 to 100, SD 20.51) postoperatively (p < 0.001), the mean VR/SF-12 scores improved significantly from physical health (PH), 31.21 (SD 5.32; 23.99 to 56.77) preoperatively to 42.62 (SD 10.72; 19.38 to 56.82) postoperatively (p < 0.001) and the mental health (MH), 38.15 (SD 8.17; 19.06 to 60.75) preoperatively to 55.09 (SD 9.64; 19.06 to 66.98) postoperatively (p < 0.001). A total of 11 revisions were undertaken, with an overall revision rate of 2.94%, including five for periprosthetic joint infection (1.34%), three for loosening (0.80%), two for instability (0.53%), and one for pain (0.27%). The overall survivorship was 97.06% and survivorship for aseptic loosening as the endpoint was 98.40%, with a 99.5% survivorship of the 3D-printed tibial component., Conclusion: This 3D-printed cementless total knee system shows excellent survivorship at mid-term follow-up. This design and the ability to obtain cementless fixation offers promise for excellent long-term durability. Cite this article: Bone Joint J 2021;103-B(6 Supple A):32-37.
- Published
- 2021
- Full Text
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47. A New Additive-Manufactured Cementless Highly Porous Titanium Acetabular Cup for Primary Total Hip Arthroplasty-Early Two-Year Follow Up.
- Author
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Abdelaal MS, Small I, Restrepo C, and Hozack WJ
- Subjects
- Acetabulum diagnostic imaging, Acetabulum surgery, Follow-Up Studies, Humans, Porosity, Prosthesis Design, Prosthesis Failure, Reoperation, Retrospective Studies, Titanium, Arthroplasty, Replacement, Hip adverse effects, Hip Prosthesis
- Abstract
Introduction: Additive-manufacturing technologies are increasingly being used, not only to create acetabular components with porous coating architecture very similar to the complex trabecular structure of cancellous bone, but also for producing the entire implant in a single step. The aim of this study is to assess two-year clinical and radiological outcomes of a new additive-manufactured cup in primary total hip arthroplasty (THA)., Materials and Methods: We reviewed 266 primary THAs (254 patients) performed in our institution between December 2016 and December 2018 using a new highly porous titanium acetabulum shell fabricated via additive manufacturing. Clinical and functional outcomes were measured using SF/VR-12 and HOOS JR to determine patient satisfaction with surgery. Radiographs were assessed to determine the presence of migration, radiolucency, and loosening. Patients records were reviewed to assess cup survivorship in terms of all-cause revisions and revision for aseptic cup loosening., Results: At a minimum of two-year follow up (range: 2-3.45 years), the patient cohort demonstrated significant improvement in postoperative functional scores (hip disability and osteoarthritis outcome score for joint replacement [HOOS JR.] and clinical scores (12-item short-form health survey [SF/VR-12]) (p<0.001). One cup developed progressive radiolucent lines at the prosthesis-bone interface consistent with loosening and was revised. The overall acetabular component two-year survivorship free of all-cause failure was 97.4% (95% confidence interval [CI]: 95.5-99.4%). When aseptic loosening of the acetabular component was used as the failure endpoint, the two-years survivorship rate was 99.6% (95% CI: 98.9-100%)., Conclusion: Highly porous titanium cementless acetabular cups produced via additive-manufacturing showed promising early clinical and radiological results in primary THA with low rates of aseptic loosening. Further follow-up studies are needed to assess the long-term survivorship and outcomes of this new acetabular component.
- Published
- 2021
- Full Text
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48. Dual Mobility and Conventional Bearings Have Comparably Low Dislocation Rates for Anterior-Based Approaches in Total Hip Arthroplasty.
- Author
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Van Nest DS, Li WT, Kozick Z, Smith EB, Hozack WJ, and Courtney PM
- Subjects
- Humans, Prosthesis Design, Prosthesis Failure, Reoperation, Retrospective Studies, Arthroplasty, Replacement, Hip adverse effects, Hip Dislocation epidemiology, Hip Dislocation etiology, Hip Dislocation surgery, Hip Prosthesis adverse effects
- Abstract
Background: Dual mobility (DM) bearings for total hip arthroplasty (THA) have been proposed to reduce the risk of instability in select patients, especially those undergoing revision surgery. The use of DM bearings has not been studied as extensively for use in primary THA. The purpose of this study is to compare outcomes following primary THA with anterior-based approaches between patients receiving DM bearings vs standard bearing hip implants., Methods: We retrospectively reviewed a consecutive series of patients undergoing primary THA through an anterior-based approach. A 3:1 propensity score match was performed between the standard and DM bearing patients to control for possible risk factors for instability. Functional outcomes, dislocations, and aseptic revisions were identified for each patient. The effect of DM on postoperative outcomes was determined using univariate statistical analyses., Results: In total, 250 DM bearings were compared to 753 standard bearings. We found no difference in dislocation rate between single bearings and DM bearings (0.53% vs 0.4%). There was 1 DM dislocation occurring in a liner with outer diameter of 38 mm. There were no DM dislocations with outer diameter >38 mm. Aseptic revision surgery was more common in DM. This difference was driven by higher incidence of femoral periprosthetic fracture. There were no differences in functional outcomes., Conclusion: Dislocation rates are comparably low between DM bearings and standard bearings for THA done using an anterior approach to the hip. Further investigation is needed to determine if specific patient populations may benefit from DM implants for primary THA when an anterior approach to the hip is being used., (Copyright © 2020 Elsevier Inc. All rights reserved.)
- Published
- 2021
- Full Text
- View/download PDF
49. Functional Outcomes are Comparable Between Posterior Stabilized and Cruciate-Substituting Total Knee Arthroplasty Designs at Short-Term Follow-up.
- Author
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Yacovelli S, Grau LC, Hozack WJ, and Courtney PM
- Subjects
- Follow-Up Studies, Humans, Knee Joint surgery, Polyethylene, Prosthesis Design, Range of Motion, Articular, Arthroplasty, Replacement, Knee, Knee Prosthesis, Osteoarthritis, Knee surgery, Posterior Cruciate Ligament surgery
- Abstract
Background: Posterior stabilized (PS) polyethylene inserts have been shown to have excellent long-term functional results following total knee arthroplasty (TKA). A cruciate-substituting (CS) design has been introduced to minimize bony resection and eliminate concerns regarding wear on the PS post. The purpose of this study is to compare the outcomes of patients who underwent TKA using either a PS or CS insert., Methods: We reviewed a consecutive series of 5970 patients who underwent a cruciate-sacrificing TKA and received either a PS (3,314) or CS (2,656) polyethylene liner. We compared demographics, Knee Injury and Osteoarthritis Outcome Score Jr (KOOS Jr), Short-Form 12 (SF-12) scores, and revision rates between the groups at a minimum 2 years followup. A multivariate regression was performed to identify the independent effect of design on functional outcomes., Results: Revision rates between the groups were comparably low (0.35% for PS vs 0.51% for CS, P = .466) at an overall mean follow-up of 43 months. Patients in the PS cohort had statistically higher KOOS Jr scores at 2 years (69.8 vs 72.9, P < .001). Multivariate regression analysis found CS patients to have lower postoperative KOOS Jr scores (estimate -2.26, P = .003), and less overall improvement in KOOS Jr scores (estimate -2.42, P = .024) than PS patients, but neither was a clinically significant difference., Conclusion: Patients who undergo TKA with a CS polyethylene insert have comparable functional outcomes and revision rates to those with a PS design at short-term follow-up. Longer follow-up is needed to determine whether CS can match the outstanding track record of PS TKA., (Copyright © 2020 Elsevier Inc. All rights reserved.)
- Published
- 2021
- Full Text
- View/download PDF
50. Mepivacaine versus Bupivacaine Spinal Anesthesia for Early Postoperative Ambulation.
- Author
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Schwenk ES, Kasper VP, Smoker JD, Mendelson AM, Austin MS, Brown SA, Hozack WJ, Cohen AJ, Li JJ, Wahal CS, Baratta JL, Torjman MC, Nemeth AC, and Czerwinski EE
- Subjects
- Aged, Anesthesia, Spinal trends, Arthroplasty, Replacement, Hip adverse effects, Arthroplasty, Replacement, Hip trends, Early Ambulation trends, Female, Humans, Male, Middle Aged, Postoperative Care trends, Anesthesia, Spinal methods, Anesthetics, Local administration & dosage, Bupivacaine administration & dosage, Early Ambulation methods, Mepivacaine administration & dosage, Postoperative Care methods
- Abstract
Background: Early ambulation after total hip arthroplasty predicts early discharge. Spinal anesthesia is preferred by many practices but can delay ambulation, especially with bupivacaine. Mepivacaine, an intermediate-acting local anesthetic, could enable earlier ambulation than bupivacaine. This study was designed to test the hypothesis that patients who received mepivacaine would ambulate earlier than those who received hyperbaric or isobaric bupivacaine for primary total hip arthroplasty., Methods: This randomized controlled trial included American Society of Anesthesiologists Physical Status I to III patients undergoing primary total hip arthroplasty. The patients were randomized 1:1:1 to 52.5 mg of mepivacaine, 11.25 mg of hyperbaric bupivacaine, or 12.5 mg of isobaric bupivacaine for spinal anesthesia. The primary outcome was ambulation between 3 and 3.5 h. Secondary outcomes included return of motor and sensory function, postoperative pain, opioid consumption, transient neurologic symptoms, urinary retention, intraoperative hypotension, intraoperative muscle tension, same-day discharge, length of stay, and 30-day readmissions., Results: Of 154 patients, 50 received mepivacaine, 53 received hyperbaric bupivacaine, and 51 received isobaric bupivacaine. Patient characteristics were similar among groups. For ambulation at 3 to 3.5 h, 35 of 50 (70.0%) of patients met this endpoint in the mepivacaine group, followed by 20 of 53 (37.7%) in the hyperbaric bupivacaine group, and 9 of 51 (17.6%) in the isobaric bupivacaine group (P < 0.001). Return of motor function occurred earlier with mepivacaine. Pain and opioid consumption were higher for mepivacaine patients in the early postoperative period only. For ambulatory status, 23 of 50 (46.0%) of mepivacaine, 13 of 53 (24.5%) of hyperbaric bupivacaine, and 11 of 51 (21.5%) of isobaric bupivacaine patients had same-day discharge (P = 0.014). Length of stay was shortest in mepivacaine patients. There were no differences in transient neurologic symptoms, urinary retention, hypotension, muscle tension, or dizziness., Conclusions: Mepivacaine patients ambulated earlier and were more likely to be discharged the same day than both hyperbaric bupivacaine and isobaric bupivacaine patients. Mepivacaine could be beneficial for outpatient total hip arthroplasty candidates if spinal is the preferred anesthesia type., (Copyright © 2020, the American Society of Anesthesiologists, Inc. All Rights Reserved.)
- Published
- 2020
- Full Text
- View/download PDF
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