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1. The Participation Status of Historically Black Colleges and Universities and Small African American-Owned Technology Firms in the Federal Assistive Technology-Research and Development Enterprise through STEM Pathways

Author

Ward-Sutton, Courtney, Moore, Corey L., Starr-Howard, Renee, Uhunoma, Osaretin, and Manyibe, Edward O.

Abstract

Purpose: This article provided a comprehensive overview of the available peer-reviewed and grey literature on the current status of historically Black colleges and universities (HBCUs) and small African American-owned technology firms participation in the federal assistive technology research and development (AT-R&D) enterprise. Method: Authors completed a historical review of the existing literature on HBCUs' participation in STEM academic pathways to AT-R&D; the contextual framework for HBCUs federal R&D barriers; STEM pathways to small African American Technology Entrepreneurship; and small African American-owned technology firms AT-R&D participation barriers. Results: Overall, the review illuminated participation barriers experienced; exacerbated in part by narrow STEM pathways designed to help African American students successfully matriculate in related disciplines, institutional systematic barriers, a lack of funding priorities within federal research agencies, and the oversight of African American entrepreneurs in AT. Conclusions: The authors presented recommendations that might be useful for developing proactive academic pipelines to AT-R&D. The literature review is among the first to examine HBCUs' participation in STEM pathways to federally-funded AT-R&D.

Published
2022
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2. “Eczema Coxsackium” and Unusual Cutaneous Findings in an Enterovirus Outbreak

Author

Mathes, Erin F, Oza, Vikash, Frieden, Ilona J, Cordoro, Kelly M, Yagi, Shigeo, Howard, Renee, Kristal, Leonard, Ginocchio, Christine C, Schaffer, Julie, Maguiness, Sheilagh, Bayliss, Susan, Lara-Corrales, Irene, Garcia-Romero, Maria Teresa, Kelly, Dan, Salas, Maria, Oberste, M Steven, Nix, W Allan, Glaser, Carol, and Antaya, Richard

Subjects
Biomedical and Clinical Sciences, Clinical Sciences, Pediatric, Skin, Academic Medical Centers, Adolescent, Child, Child, Preschool, Coxsackievirus Infections, Cross-Sectional Studies, Diagnosis, Differential, Disease Outbreaks, Eczema, Female, Hand, Foot and Mouth Disease, Humans, Infant, Male, North America, Retrospective Studies, hand, foot, and mouth disease, coxsackievirus, atopic dermatitis, exanthem, hand, foot, and mouth disease, Medical and Health Sciences, Psychology and Cognitive Sciences, Pediatrics, Biomedical and clinical sciences, Health sciences, Psychology
Abstract

ObjectiveTo characterize the atypical cutaneous presentations in the coxsackievirus A6 (CVA6)-associated North American enterovirus outbreak of 2011-2012.MethodsWe performed a retrospective case series of pediatric patients who presented with atypical cases of hand, foot, and mouth disease (HFMD) from July 2011 to June 2012 at 7 academic pediatric dermatology centers. Patients were included if they tested positive for CVA6 or if they met clinical criteria for atypical HFMD (an enanthem or exanthem characteristic of HFMD with unusual morphology or extent of cutaneous findings). We collected demographic, epidemiologic, and clinical data including history of skin conditions, morphology and extent of exanthem, systemic symptoms, and diagnostic test results.ResultsEighty patients were included in this study (median age 1.5 years, range 4 months-16 years). Seventeen patients were CVA6-positive, and 63 met clinical inclusion criteria. Ninety-nine percent of patients exhibited a vesiculobullous and erosive eruption; 61% of patients had rash involving >10% body surface area. The exanthem had a perioral, extremity, and truncal distribution in addition to involving classic HFMD areas such as palms, soles, and buttocks. In 55% of patients, the eruption was accentuated in areas of eczematous dermatitis, termed "eczema coxsackium." Other morphologies included Gianotti-Crosti-like (37%), petechial/purpuric (17%) eruptions, and delayed onychomadesis and palm and sole desquamation. There were no patients with serious systemic complications.ConclusionsThe CVA6-associated enterovirus outbreak was responsible for an exanthem potentially more widespread, severe, and varied than classic HFMD that could be confused with bullous impetigo, eczema herpeticum, vasculitis, and primary immunobullous disease.

Published
2013

4. Contributors

Author

Abdallah, M. Abdel Rahim, Abdallah, Mahmoud M.A., Abdallah, Marwa, Adler, Brandon L., Adusumilli, Nagasai C., Akaike, Tomoko, Alavi, Afsaneh, Amagai, Masayuki, Ambros-Rudolph, Priv.-Doz. Dr. Christina M., Rox Anderson, R., Antaya, Richard J., Ardigò, Marco, Argenyi, Zsolt B., Argenziano, Giuseppe, Avram, Marc R., Avram, Mathew M., Baker, Christopher, Barete, Stéphane, Barnhill, Raymond L., Baselga, Eulalia, Baugh, Erica G., Bayliss, Susan J., Beck, Lisa A., Bergqvist, Christina, Bernhard, Jeffrey D., Blanton, Lucas S., Bodemer, Apple, Bolognia, Jean L., Borradori, Luca, Dominik Braun, Andreas, Bravo, Francisco G., Brodland, David G., Brownell, Isaac, Bruckner, Anna L., Bruckner-Tuderman, Leena, Burkhart, Craig G., Burkhart, Craig N., Burrows, Nigel P., Callen, Jeffrey P., Camacho, Francisco M., Cameli Carley, Alexandra, Carruthers, Alastair, Carruthers, Jean, Cartee, Todd V., Cerroni, Lorenzo, Chan, Roy K.W., Wu Chang, Mary, Chio, Martin T.W., Chosidow, Olivier, Christiano, Angela M., Clayton, Anna S., Cockerell MD MBA JD, Clay J., Cohen, Bernard A., Cohen, David E., Coleman, Kyle M., Coleman, William P., Kari Connolly, M., Cooper, Susan M., Corey, Kristen, Cowen, Edward W., Cribier, Bernard, Darling, Thomas N., Davis, Mark D.P., de Berker, David, De Leo, Vincent A., Detmar, Michael, Diana Draelos, Zoe, Duncan, Karynne O., Elewski, Boni E., Elias, Peter M., Elston, Dirk M., Eming, Sabine A., España, Agustín, Fairley, Janet A., Feingold, Kenneth R., Fine, Jo-David, Flowers, Franklin P., Fox, Matthew, Fraitag, Sylvie, Franceschini, Chiara, Frank, Jorge, French, Lars E., Fried, Isabella, Frieden, Ilona J., Garzon, Maria C., Gasslitter, Irina, Gattorno, Marco, Gehlhausen, Jeffrey R., Ghoreschi, Kamran, Goldman, Mitchel P., Goldsmith, Charya B., Gollnick, Harald P., Grattan, Clive E.H., Groves, Richard W., Guillén-Navarro, Encarna, Haemel, Anna K., Hafner, Ariela, Haggstrom, Anita N., Hand, Jennifer L., Hannam, Sarah, Hausauer, Amelia K., Hay, Roderick J., Helfrich, Yolanda R., Hernández-Martín, Ángela, Hertl, Michael, Heymann, Warren R., High, Whitney A., Hirakawa, Satoshi, Hivnor, Chad M., Hohl, Prof. Dr. med. Daniel M., Hönigsmann, Herbert, Hötzenecker, Wolfram, Howard, Josie, Howard, Renee M., Hruza, George J., Hrynewycz, Katherine, Hsiao, Jennifer L., Huang, Jennifer T., Hughey, Lauren C., Hull, Christopher M., Marchiony Hunt, Katherine, Ingen-Housz-Oro, Saskia, Irvine, Alan D., Iversen, Lars, Mark Jackson, J., Jackson, Scott M., Jacobe, Heidi T., Jebain, Joseph, Jessri, Maryam, Jones, Derek H., Jorizzo, Joseph L., Kaddu, Steven, Kalia, Sunil, Kang, Sewon, Kelly, Kristen M., Kelly, Robert, Kempf, Werner, Kim, Brian, Kirnbauer, Reinhard, Kirsner, Robert S., Kittler, Nicole W., Knowles BSc Phm, Sandra R., Ko, Christine J., Kocatürk, Emek, Koch, Priv.-Doz. Dr. Lukas, Koch, Peter J., Koh, Hong Yi, Koo, John Y.M., Koss, Tamara, Koster, Maranke I., Kroshinsky, Daniela, G. Kumar, Monique, Kutzner, Heinz H., Kwong, Bernice Y., Lalor, Leah E.B., Lam, Charlene, Latheef, Faheem, Lee, Lela A., Lenormand, Cédric, Lenz, Petra, Lesher, Jack L., Jr., Leslie, Kieron S., Lev-Tov, Hadar, Liegl-Atzwanger, Bernadette, Lim, Henry W., Hua Liang Lim, Joel, Linos, Eleni, Lio, Peter, Lipsker, Dan, Loomis, Cynthia A., Lui, Harvey, Luo, Su, Maari, Catherine, Machan, Salma, Madigan, Lauren M., Maguiness, Sheilagh M., Maiberger, Mary P., Mancini, Anthony J., Marchitto, Mark, Marks Jr, James G., Martínez-Menchón, Teresa, Mascaró, José M., Jr., Trent Massengale, William, Massone, Cesare, Mauro, Theodora M., Mc Aleer, Maeve A., Mc Calmont, Timothy H., Carol Mc Connell, R., Mc Govern, Thomas W., Matthew Mc Larney, R., Mc Meniman, Erin K., Mc Murray, Stacy L., Mc Namara, Kristin K., Mc Niff, Jennifer M., Mellerio, Jemima E., Menon, Gopinathan K., Metze, Dieter, Meyer, Jason, Micheletti, Robert G., Milam, Emily C., Millard-Garcia, Ashley N., Miller, Jami L., Mizukawa, Yoshiko, Molho-Pessach, Vered, Molina-Ruiz, Ana María, Monheit, Gary D., Morrell, Dean S., Mowad, Christen M., Mahindra Nayyar, Priya, Nelson, Amanda M., Nghiem, Paul, Ní Raghallaigh, Síona, Nixon AM, Rosemary L., Noguera-Morel, Lucero, North, Paula E., Nunley, Julia R., Nyström, Alexander, Teresa Ochoa, Maria, Oji, Vinzenz, Olbricht, Suzanne, Orlow, Seth J., Ortega-Loayza, Alex G., Ortonne, Jean-Paul, Oschmann, Anna, Paller, Amy S., Pasquali, Paola, Passeron, Thierry, Patterson, James W., P. Pereira, Manuel, Pfisterer, Karin, Piette, Warren W., Pincus, Laura B., Maria Piraccini, Bianca, Pittelkow, Mark R., Plewig, Gerd, Pollack, Sheldon V., Powell, Julie, Prausnitz, Mark R., Quist, Jennifer E., Quist, Sven R., Qureshi, Abrar A., Raimer, Ben G., Raimer, Sharon S., Raimer-Goodman, Lauren, Ramachandran, Sarika, Ramos-e-Silva, Marcia, Rapini, Ronald P., Ratner, Désirée, Reboli, Annette C., Reider, Norbert, Reizner, George T., Requena, Celia, Requena, Luis, Reynolds, Rachel, Cristina Ribeiro de Castro, Maria, Rich, Phoebe, Richard, Gabriele, Richards, Shawn W., Richert, Bertrand, Ringpfeil, Franziska, Röcken, Martin, Rogers MD FAAD, Nicole E., Rohrer, Thomas E., Rongioletti, Franco, Rosen, Cheryl F., Rosenbach, Misha A., Rudnicka, Lidia, Rünger, Thomas M., Saggini, Andrea, Saini, Sarbjit S., Sakamoto, Fernanda H., Saurat, Jean-Hilaire, Schadt, Courtney R., Ann Mc Leish, Stephanie, Schaffer, Julie V., Schaller, Martin, Schmuth, Matthias, Schwarz, Thomas, Schwarzenberger, Kathryn, Seneschal, Julien, Shani-Adir, Ayelet, Shapiro, Lori E., Shear, Neil H., Shi, Vivian Y., Shields, Bridget E., Shiohara, Tetsuo, Sidbury, Robert, Siller, Alfredo, Jr., Sivamani, Raja, Smith, Gideon P., Smith, Michael L., Smoller, Bruce R., Sommer, Lacy L., Sontheimer, Richard D., Sorg, Olivier, Peter Soyer, H., Sprecher, Eli, Ständer, Sonja, Stary, Angelika, Stary, Georg, Steadmon, Matthew, Stefanato, Catherine M., Seabury Stone, Mary, Stratman, Erik J., Süßmuth, Kira, Swetter, Susan M., Sybert, Virginia P., Hoon Tan, Suat, Tanzi, Elizabeth, Liang Tey, Hong, Tharp, Michael D., Tomasini, Carlo F., Torrelo, Antonio, Tosti, Antonella, Travelute, Christie R., Treister, Nathaniel, Trindade de Almeida, Ada Regina, Tsao, Hensin, Tschandl, Philipp, Tüting, Thomas, Tyring, Stephen K., Uitto, Jouni, van de Kerkhof, Peter C.M., Vandergriff, Travis W., Veness, Michael J., Verhave, Brendon, Vidimos, Allison T., Virós, Amaya, Ann Vleugels, Ruth, Walker, David H., Wanat, Karolyn A., Wang, Etienne C.E., Wang, Jennifer Y., Watsky, Kalman L., Weber, Benedikt, Weiss, Robert A., Weisshaar, Elke, Weninger, Wolfgang, Werth, Victoria P., Wesley, Naissan O., Weston, Gillian K., Whittaker, Sean, Wiesner, Thomas, Mark Wilkinson, S., Willemze, Rein, Winfield, Harry L., Wolf, Ingrid H., Wolf, Peter, Wolverton, Stephen E., Wood, Gary S., Yancey, Kim B., Yang, Eric J., Yang, Yul W., Yosipovitch, Gil, Rasar Young, Melissa, Zaba, Lisa C., Zachary, Christopher B., Zaenglein, Andrea L., Zalaudek, Iris, and Zone, John J.

Published
2025
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8. List of Contributors

Author

Antaya, Richard J., primary, Baselga, Eulalia, additional, Bernard, Laurie A., additional, Bradley, John S., additional, Bree, Alanna F., additional, Bruckner, Anna L., additional, Burkhart, Craig N., additional, Carder, K. Robin, additional, Chan, Yuin-Chew, additional, Chu, David H., additional, Cohen, Bernard A., additional, Cunningham, Bari B., additional, Dinulos, James G.H., additional, Drolet, Beth A., additional, Enjolras, Odile, additional, Friedlander, Sheila Fallon, additional, Galbraith, Sheila S., additional, Garzon, Maria C., additional, Gibbs, Neil F., additional, Gilliam, Amy E., additional, Hebert, Adelaide A., additional, Honig, Paul J., additional, Howard, Renee J., additional, Irvine, Alan D., additional, Kim, Ho Jin, additional, Kos, Liborka, additional, Koss, Tamara, additional, Krafchik, Bernice R., additional, Krol, Alfons L., additional, Lawley, Leslie P., additional, Levy, Moise L., additional, Loomis, Cynthia A., additional, Lucky, Anne W., additional, Makkar, Hanspaul S., additional, Mancini, Anthony J., additional, Metry, Denise W., additional, Metz, Brandie J., additional, Morrell, Dean S., additional, Pace, Nicole C., additional, Paller, Amy S., additional, Prendiville, Julie S., additional, Prose, Neil S., additional, Rogers, Maureen, additional, Siegel, Dawn, additional, Siegfried, Elaine C., additional, Silverman, Robert A., additional, Tay, Yong-Kwang, additional, Torrelo, Antonio, additional, Wagner, Annette M., additional, Williams, Mary L., additional, Wong, Li-Chuen, additional, and Yan, Albert C., additional

Published
2008
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10. Evaluating restoration success by tracking the structural and functional recovery of restored, drained, and intact wetlands

Author

Howard, Renee C.

Subjects
recovery, Prairie Pothole Region, Natural Resources and Conservation, food and beverages, plant, functional traits, wetland, chronosequence
Abstract

Wetland restoration efforts have increased on the Canadian prairies to compensate for widespread loss of wetland area, form, and function. Restoration activity presumes a direct replacement for natural wetlands, where restored wetlands provide equivalent ecological functions and services. However, restoration projects often show limited recovery success in biological structure and biogeochemical function. Using plant functional traits is an emerging approach to assessing ecological process and may provide a better indicator of wetland functional recovery than vegetation structural indicators alone. Here, I tracked vegetation structural metrics (i.e., species richness, composition, and cover) and plant functional traits over a chronosequence of restored wetlands to compare structural and functional recovery and evaluate restoration success. Results suggest rapid structural recovery (within five years of restoration) and similar functional diversity among drained, restored, and natural wetlands. The approach taken towards wetland restoration, combined with a heavily impacted agricultural landscape, may be limiting the recovery potential of wetlands, thereby creating a homogenization of wetland form and function.

Published
2019

15. Hamartomas and midline anomalies in association with infantile hemangiomas, PHACE, and LUMBAR syndromes

Author

Stefanko, Nicole S., primary, Davies, Olivia M.T., additional, Beato, Maria Jose, additional, Blei, Francine, additional, Drolet, Beth A., additional, Fairley, Janet, additional, Frieden, Ilona J., additional, Galligan, Eloise R., additional, Goddard, Deborah, additional, Howard, Renee, additional, Husain, Sameera, additional, Lauren, Christine T., additional, Lopez‐Gutierrez, Juan Carlos, additional, MacArthur, Carol, additional, Metry, Denise W., additional, Morel, Kimberly D., additional, Niedt, George W., additional, Garzon, Maria C., additional, Sokumbi, Olayemi, additional, and Siegel, Dawn H., additional

Published
2019
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20. Hamartomas and midline anomalies in association with infantile hemangiomas, PHACE, and LUMBAR syndromes.

Author

Stefanko, Nicole S., Davies, Olivia M.T., Beato, Maria Jose, Blei, Francine, Drolet, Beth A., Fairley, Janet, Frieden, Ilona J., Galligan, Eloise R., Goddard, Deborah, Howard, Renee, Husain, Sameera, Lauren, Christine T., Lopez‐Gutierrez, Juan Carlos, MacArthur, Carol, Metry, Denise W., Morel, Kimberly D., Niedt, George W., Garzon, Maria C., Sokumbi, Olayemi, and Siegel, Dawn H.

Subjects
HEMANGIOMAS, SYNDROMES, PATHOLOGY, HAMARTOMA, PERICARDIUM
Abstract

Background/Objective: The pathogenesis of infantile hemangiomas (IH), PHACE, and LUMBAR syndromes remains unknown. We aim to describe histopathologic features of midline anomalies associated with IH, including patients with PHACE and LUMBAR syndromes. Methods: A multicenter retrospective chart review was performed to identify patients with IH, PHACE, and LUMBAR syndrome with histopathologic specimens from sternal or midline anomalies. A total of 18 midline lesions from 13 patients were included. Out of 18, 14 midline lesions underwent both histopathologic and clinical review. Three hamartoma‐like chin plaques and one supraumbilical raphe underwent only clinical review. Results: All 13 patients had midline lesions and IH. Histopathologic diagnoses were as follows: rhabdomyomatous mesenchymal hamartoma (3), folliculosebaceous cystic hamartoma (1), fibroepithelial polyp (1), verrucous epidermal hyperplasia with vascular proliferation and fibroplasia (1), congenital midline cervical cleft (1), pericardium with fibrosis (1), fibrous components with increased collagen (1), atrophic skin/membrane (3), angiolipomatous mass with neural components (1), and lipomatous mass (1). Due to the retrospective nature of this study, it was not possible to obtain pathology slides for all midline lesions that had previously been biopsied or resected. We show clinically and histopathologically a new association between PHACE syndrome and rhabdomyomatous mesenchymal hamartoma (RMH), in addition to demonstrating the association between PHACE syndrome and chin hamartomas. We also display histopathologic findings seen in midline lesions resected from LUMBAR patients. Conclusion: Rhabdomyomatous mesenchymal hamartoma is thought to be related to aberrations of mesenchymal cells during development; therefore, this may provide clues to the pathogenesis of IH and related syndromes. [ABSTRACT FROM AUTHOR]

Published
2020
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21. Incomplete recovery of plant diversity in restored prairie wetlands on agricultural landscapes.

Author

Salaria, Saloni, Howard, Renee, Clare, Shari, and Creed, Irena F.

Subjects
*WETLANDS, *PRAIRIES, *PLANT diversity, *PLANT gene banks, *SPECIES diversity, *INTRODUCED species
Abstract

Restoration efforts are being implemented globally to mitigate the degradation and loss of wetland habitat; however, the rate and success of wetland vegetation recovery post‐restoration is highly variable across wetland classes and geographies. Here, we measured the recovery of plant diversity along a chronosequence of restored temporary and seasonal prairie wetlands ranging from 0 to 23 years since restoration, including drained and natural wetlands embedded in agricultural and natural reserve landscapes in central Alberta, Canada. We assessed plant diversity using the following structural indicators: percent cover of hydrophytes, native and non‐native species, species richness, and community composition. Our findings indicate that plant diversity recovered to resemble reference wetlands in agricultural landscapes within 3–5 years of restoration; however, restored wetlands maintained significantly lower species richness and a distinct community composition compared to reference wetlands located within natural reserves. Early establishment of non‐native species during recovery, dispersal limitation, and depauperated native seed bank were probable barriers to complete recovery. Determining the success of vegetation recovery provides important knowledge that can be used to improve restoration strategies, especially considering projected future changes in land use and climate. [ABSTRACT FROM AUTHOR]

Published
2019
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22. Colaboradores

Author

Abdallah, M. Abdel Rahim, Abdallah, Mahmoud M.A., Abdallah, Marwa, Akiyama, Tasuku, Alavi, Afsaneh, Allen, Carl M., Amagai, Masayuki, Ambros-Rudolph, Christina M., Anderson, R. Rox, Antaya, Richard J., Argenyi, Zsolt B., Argenziano, Giuseppe, Arin, Meral J., Asplund, Anna, Avram, Mathew M., Avram, Marc R., Bacigalupi, Robert, Baker, Christopher, Balin, Samuel J., Barnhill, Raymond L., Barrett, Terry L., Baselga, Eulalia, Bauer, Jürgen, Bayliss, Susan J., Beleznay, Katie, Bernard, Philippe, Bernhard, Jeffrey D., Blanton, Lucas S., Bolognia, Jean L., Borradori, Luca, Bravo, Francisco G., Bree, Alanna F., Brodland, David G., Browne, Fiona, Brownell, Isaac, Bruckner-Tuderman, Leena, Burkhart, Craig G., Burkhart, Craig N., Burrows, Nigel P., Burton, Barbara K., Callen, Jeffrey P., Camacho, Francisco M., Camisa, Charles, Carley, Alexandra Cameli, Carruthers, Alastair, Carruthers, Jean, Cartee, Todd V., Cerroni, Lorenzo, Chan, Roy K.W., Chang, Mary Wu, Chastain, Mark A., Chio, Martin T.W., Christiano, Angela M., Clayton, Anna S., Cockerell, Clay J., Cohen, Bernard A., Cohen, David E., Cole, John P., Colegio, Oscar R., Coleman, Kyle M., Coleman, William P., III, Connolly, M. Kari, Cooper, Susan M., Cowen, Edward W., Cropley, Thomas G., Curtis, Ashley R., Darling, Thomas N., Davis, Mark D.P., Berker, David de, DeLeo, Vincent A., DeStefano, Gina M., Detmar, Michael, Divine, Jennifer, Downing, Christopher, Draelos, Zoe Diana, Duncan, Karynne O., Dutz, Jan P., Shabrawi-Caelen, Laila El, Elewski, Boni E., Elias, Peter M., Elston, Dirk M., Eming, Sabine A., España, Agustín, Fairley, Janet A., Feingold, Kenneth R., Fine, Jo-David, Fleischer, Alan B., Jr., Flowers, Franklin P., Flynn, Timothy C., Fox, Lindy P., Fox, Matthew, Frank, Jorge, Franz, Thomas J., French, Lars E., Frieden, Ilona J., Fritsch, Peter O., Garbe, Claus, Garzon, Maria C., Gattorno, Marco, Lamo, Josep Genebriera de, Ghoreschi, Kamran, Goldman, Mitchel P., Goldsmith, Charya B., Gollnick, Harald P., Goodman, Warren T., Grattan, Clive E.H., Groves, Richard W., Guzman-Sanchez, Daniela, Hafner, Ariela, Haggstrom, Anita N., Hawk, John L.M., Hay, Roderick J., Helfrich, Yolanda, Hernández-Martín, Ángela, Heymann, Warren R., High, Whitney A., Hirakawa, Satoshi, Hivnor, Chad M., Hohl, Daniel, Hönigsmann, Herbert, Hötzenecker, Wolfram, Howard, Renee M., Hruza, George J., Hsiao, Jennifer L., Hughey, Lauren C., Hull, Christopher M., Hunt, Katherine Marchiony, Irvine, Alan D., Itin, Peter H., Jackson, J. Mark, Jackson, Scott M., Jacobe, Heidi T., Jones, Derek H., Jorizzo, Joseph L., Kaddu, Steven, Kamino, Hideko, Kang, Sewon, Kasprowicz, Sarah, Keene, Sharon A., Kelly, Kristen M., Kelly, Robert, Kirnbauer, Reinhard, Kirsner, Robert S., Knowles, Sandra R., Ko, Christine J., Koch, Peter J., Koh, Hong Yi, Koo, John Y.M., Korcheva, Veselina, Koss, Tamara, Koster, Maranke I., Kroshinsky, Daniela, Kumar, Monique G., Kutzner, Heinz H., Lam, Charlene, Lane, Kathryn Serowka, Lang, Estefanía, Lee, Lela A., Legat, Franz J., Leiferman, Kristin M., Lenz, Petra, Lesher, Jack L., Jr., Leslie, Kieron S., Lim, Henry W., Linos, Eleni, Lio, Peter A., Lipsker, Dan, Loomis, Cynthia A., Lui, Harvey, Luo, Su, Lundeberg, Joakim, Maari, Catherine, Machan, Salma, Nayyar, Priya Mahindra, Maiberger, Mary P., Mancini, Anthony J., Marks, James G., Jr., Mascaró, José M., Jr., Massengale, William Trent, Massone, Cesare, McAleer, Maeve A., McCalmont, Timothy H., McConnell, R. Carol, McGovern, Thomas W., McMeniman, Erin, McMichael, Amy J., McNamara, Kristin K., McNiff, Jennifer M., Mellerio, Jemima E., Mendoza, Natalia, Menon, Gopinathan K., Metze, Dieter, Miller, Jami L., Millican, Eric A., Mizukawa, Yoshiko, Pessach, Vered Molho, Molina-Ruiz, Ana María, Monheit, Gary D., Morrell, Dean S., Moschella, Samuel L., Moss, Celia, Mowad, Christen M., Nestlé, Frank O., Raghallaigh, Síona Ní, Nixon, Rosemary L., Noguera-Morel, Lucero, North, Paula E., Nunley, Julia R., Nyström, Alexander, Obeid, Grace, Oji, Vinzenz, Olbricht, Suzanne, O’Regan, Grainne M., Orlow, Seth J., Ortonne, Jean-Paul, O’Toole, Edel A., Paller, Amy S., Pasquali, Paola, Passeron, Thierry, Patterson, James W., Peters, Margot S., Piette, Warren W., Pincus, Laura B., Piraccini, Bianca Maria, Pittelkow, Mark R., Plewig, Gerd, Poblete-Gutiérrez, Pamela A., Pollack, Sheldon V., Pontén, Fredrik, Powell, Frank C., Powell, Julie, Prausnitz, Mark R., Prins, Christina, Pui, John, Quist, Jennifer, Quist, Sven R., Qureshi, Abrar A., Raimer, Ben G., Raimer, Sharon S., Goodman, Lauren Raimer, Ramos-e-Silva, Marcia, Rapini, Ronald P., Ratner, Désirée, Reboli, Annette C., Reddy, Vijaya B., Reider, Norbert, Reisenauer, Amy, Reizner, George T., Requena, Celia, Requena, Luis, Revuz, Jean, Castro, Maria Cristina Ribeiro de, Rich, Phoebe, Richard, Gabriele, Richards, Shawn W., Richer, Vincent, Richert, Bertrand, Rigel, Darrell S., Ringpfeil, Franziska, Röcken, Martin, Rogers, Nicole E., Rohrer, Thomas E., Rongioletti, Franco, Roop, Dennis R., Rosen, Cheryl F., Rosenbach, Misha A., Rünger, Thomas M., Saini, Sarbjit S., Sakamoto, Fernanda H., Sanchez, Miguel, Prof, Jean-Hilaire Saurat, Saxton-Daniels, Stephanie, Schadt, Courtney R., Schaefer, Stephanie McLeish, Schaffer, Julie V., Schaller, Martin, Schmuth, Matthias, Schwarz, Thomas, Schwarzenberger, Kathryn, Adir, Ayelet Shani, Shapiro, Lori E., Shear, Neil H., Shiohara, Tetsuo, Shinkai, Kanade, Sidbury, Robert, Sinclair, Rodney D., Smith, Michael L., Smoller, Bruce R., Sofen, Bryan D., Sommer, Lacy L., Sontheimer, Richard D., Sorg, Olivier, Soyer, H. Peter, Sperling, Leonard C., Sprecher, Eli, Sra, Karan, Stary, Angelika, Stary, Georg, Steadmon, Matthew, Stone, Mary Seabury, Stough, Dowling B., Stratman, Erik J., Sybert, Virginia P., Tan, Suat Hoon, Tang, Mark Boon Yang, Tey, Hong Liang, Tharp, Michael D., Thiboutot, Diane M., Tomasini, Carlo Francesco, Tosti, Antonella, Travelute, Christie R., Almeida, Ada Trindade de, Tsai, Jui-Chen, Tsao, Hensin, Tyring, Stephen K., Uitto, Jouni, Valeyrie-Allanore, Laurence, Kerkhof, Peter C. M. van de, Vandergriff, Travis W., Veness, Michael J., Vidimos, Allison T., Vleugels, Ruth Ann, Walker, David H., Wanat, Karolyn A., Wang, Etienne, Weisshaar, Elke, Weiss, Robert A., Werth, Victoria P., Wesley, Naissan O., Wetter, David A., White, Clifton R., Jr., White, Kevin P., Whittaker, Sean, Wilkinson, S. Mark, Willemze, Rein, Winfield, Harry L., Wojnarowska, Fenella, Wolverton, Stephen E., Wood, Gary S., Yancey, Kim B., Yosipovitch, Gil, Zachary, Christopher B., Zaenglein, Andrea L., Zalaudek, Iris, and Zone, John J.

Published
2019
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25. List of Contributors

Author

Abdallah, M. Abdel Rahim, Abdallah, Mahmoud M.A., Abdallah, Marwa, Akiyama, Tasuku, Alavi, Afsaneh, Allen, Carl M., Amagai, Masayuki, Ambros-Rudolph, Christina M., Anderson, R. Rox, Antaya, Richard J., Argenyi, Zsolt B., Argenziano, Giuseppe, Arin, Meral J., Asplund, Anna, Avram, Mathew M., Avram, Marc R., Bacigalupi, Robert, Baker, Christopher, Balin, Samuel J., Barnhill, Raymond L., Barrett, Terry L., Baselga, Eulalia, Bauer, Jürgen, Bayliss, Susan J., Beleznay, Katie, Bernard, Philippe, Bernhard, Jeffrey D., Blanton, Lucas S., Bolognia, Jean L., Borradori, Luca, Bravo, Francisco G., Bree, Alanna F., Brodland, David G., Browne, Fiona, Brownell, Isaac, Bruckner-Tuderman, Leena, Burkhart, Craig G., Burkhart, Craig N., Burrows, Nigel P., Burton, Barbara K., Callen, Jeffrey P., Camacho, Francisco M., Camisa, Charles, Carley, Alexandra Cameli, Carruthers, Alastair, Carruthers, Jean, Cartee, Todd V., Cerroni, Lorenzo, Chan, Roy K.W., Chang, Mary Wu, Chastain, Mark A., Chio, Martin T.W., Christiano, Angela M., Clayton, Anna S., Cockerell, Clay J., Cohen, Bernard A., Cohen, David E., Cole, John P., Colegio, Oscar R., Coleman, Kyle M., Coleman, William P., III, Connolly, M. Kari, Cooper, Susan M., Cowen, Edward W., Cropley, Thomas G., Curtis, Ashley R., Darling, Thomas N., Davis, Mark D.P., de Berker, David, DeLeo, Vincent A., DeStefano, Gina M., Detmar, Michael, Divine, Jennifer, Downing, Christopher, Draelos, Zoe Diana, Duncan, Karynne O., Dutz, Jan P., El Shabrawi-Caelen, Laila, Elewski, Boni E., Elias, Peter M., Elston, Dirk M., Eming, Sabine A., España, Agustín, Fairley, Janet A., Feingold, Kenneth R., Fine, Jo-David, Fleischer, Alan B., Jr., Flowers, Franklin P., Flynn, Timothy C., Fox, Lindy P., Fox, Matthew, Frank, Jorge, Franz, Thomas J., French, Lars E., Frieden, Ilona J., Fritsch, Peter O., Garbe, Claus, Garzon, Maria C., Gattorno, Marco, de Lamo, Josep Genebriera, Ghoreschi, Kamran, Goldman, Mitchel P., Goldsmith, Charya B., Gollnick, Harald P., Goodman, Warren T., Grattan, Clive E.H., Groves, Richard W., Guzman-Sanchez, Daniela, Hafner, Ariela, Haggstrom, Anita N., Hawk, John L.M., Hay, Roderick J., Helfrich, Yolanda, Hernández-Martín, Ángela, Heymann, Warren R., High, Whitney A., Hirakawa, Satoshi, Hivnor, Chad M., Hohl, Daniel, Hönigsmann, Herbert, Hötzenecker, Wolfram, Howard, Renee M., Hruza, George J., Hsiao, Jennifer L., Hughey, Lauren C., Hull, Christopher M., Hunt, Katherine Marchiony, Irvine, Alan D., Itin, Peter H., Jackson, J. Mark, Jackson, Scott M., Jacobe, Heidi T., Jones, Derek H., Jorizzo, Joseph L., Kaddu, Steven, Kamino, Hideko, Kang, Sewon, Kasprowicz, Sarah, Keene, Sharon A., Kelly, Kristen M., Kelly, Robert, Kirnbauer, Reinhard, Kirsner, Robert S., Knowles, Sandra R., Ko, Christine J., Koch, Peter J., Koh, Hong Yi, Koo, John Y.M., Korcheva, Veselina, Koss, Tamara, Koster, Maranke I., Kroshinsky, Daniela, Kumar, Monique G., Kutzner, Heinz H., Lam, Charlene, Lane, Kathryn Serowka, Lang, Estefanía, Lee, Lela A., Legat, Franz J., Leiferman, Kristin M., Lenz, Petra, Lesher, Jack L., Jr., Leslie, Kieron S., Lim, Henry W., Linos, Eleni, Lio, Peter A., Lipsker, Dan, Loomis, Cynthia A., Lui, Harvey, Luo, Su, Lundeberg, Joakim, Maari, Catherine, Machan, Salma, Mahindra Nayyar, Priya, Maiberger, Mary P., Mancini, Anthony J., Marks, James G., Jr., Mascaro, José M., Jr., Massengale, William Trent, Massone, Cesare, McAleer, Maeve A., McCalmont, Timothy H., McConnell, R. Carol, McGovern, Thomas W., McMeniman, Erin, McMichael, Amy J., McNamara, Kristin K., McNiff, Jennifer M., Mellerio, Jemima E., Mendoza, Natalia, Menon, Gopinathan K., Metze, Dieter, Miller, Jami L., Millican, Eric A., Mizukawa, Yoshiko, Molho-Pessach, Vered, Molina-Ruiz, Ana María, Monheit, Gary D., Morrell, Dean S., Moschella, Samuel L., Moss, Celia, Mowad, Christen M., Nestlé, Frank O., Ní Raghallaigh, Síona, Nixon, Rosemary L., Noguera-Morel, Lucero, North, Paula E., Nunley, Julia R., Nyström, Alexander, Obeid, Grace, Oji, Vinzenz, Olbricht, Suzanne, O’Regan, Grainne M., Orlow, Seth J., Ortonne, Jean-Paul, O'Toole, Edel A., Paller, Amy S., Pasquali, Paola, Passeron, Thierry, Patterson, James W., Peters, Margot S., Piette, Warren W., Pincus, Laura B., Piraccini, Bianca Maria, Pittelkow, Mark R., Plewig, Gerd, Poblete-Gutiérrez, Pamela A., Pollack, Sheldon V., Pontén, Fredrik, Powell, Frank C., Powell, Julie, Prausnitz, Mark R., Prins, Christina, Pui, John, Quist, Jennifer, Quist, Sven R., Qureshi, Abrar A., Raimer, Ben G., Raimer, Sharon S., Raimer-Goodman, Lauren, Ramos-e-Silva, Marcia, Rapini, Ronald P., Ratner, Désirée, Reboli, Annette C., Reddy, Vijaya B., Reider, Norbert, Reisenauer, Amy, Reizner, George T., Requena, Celia, Requena, Luis, Revuz, Jean, Ribeiro de Castro, Maria Cristina, Rich, Phoebe, Richard, Gabriele, Richards, Shawn W., Richer, Vincent, Richert, Bertrand, Rigel, Darrell S., Ringpfeil, Franziska, Röcken, Martin, Rogers, Nicole E., Rohrer, Thomas E., Rongioletti, Franco, Roop, Dennis R., Rosen, Cheryl F., Rosenbach, Misha A., Rünger, Thomas M., Saini, Sarbjit S., Sakamoto, Fernanda H., Sanchez, Miguel, Saurat, Jean-Hilaire, Saxton-Daniels, Stephanie, Schadt, Courtney R., McLeish Schaefer, Stephanie, Schaffer, Julie V., Schaller, Martin, Schmuth, Matthias, Schwarz, Thomas, Schwarzenberger, Kathryn, Shani-Adir, Ayelet, Shapiro, Lori E., Shear, Neil H., Shiohara, Tetsuo, Shinkai, Kanade, Sidbury, Robert, Sinclair, Rodney D., Smith, Michael L., Smoller, Bruce R., Sofen, Bryan D., Sommer, Lacy L., Sontheimer, Richard D., Sorg, Olivier, Soyer, H. Peter, Sperling, Leonard C., Sprecher, Eli, Sra, Karan, Stary, Angelika, Stary, Georg, Steadmon, Matthew, Stone, Mary Seabury, Stough, Dowling B., Stratman, Erik J., Sybert, Virginia P., Tan, Suat Hoon, Tang, Mark Boon Yang, Tey, Hong Liang, Tharp, Michael D., Thiboutot, Diane M., Tomasini, Carlo Francesco, Tosti, Antonella, Travelute, Christie R., Trindade de Almeida, Ada, Tsai, Jui-Chen, Tsao, Hensin, Tyring, Stephen K., Uitto, Jouni, Valeyrie-Allanore, Laurence, van de Kerkhof, Peter C.M., Vandergriff, Travis W., Veness, Michael J., Vidimos, Allison T., Vleugels, Ruth Ann, Walker, David H., Wanat, Karolyn A., Wang, Etienne, Weisshaar, Elke, Weiss, Robert A., Werth, Victoria P., Wesley, Naissan O., Wetter, David A., White, Clifton R., Jr., White, Kevin P., Whittaker, Sean, Wilkinson, S. Mark, Willemze, Rein, Winfield, Harry L., Wojnarowska, Fenella, Wolverton, Stephen E., Wood, Gary S., Yancey, Kim B., Yosipovitch, Gil, Zachary, Christopher B., Zaenglein, Andrea L., Zalaudek, Iris, and Zone, John J.

Published
2018
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26. Oral and Genital Ulceration

Author

Kwong,, Pearl C., O'Marcaigh,, Aengus S., Howard, Renee, Cowan, Morton J., and Frieden, Ilona J.

Subjects
Ulcers -- Research, Lymphatic diseases -- Diagnosis, Health
Published
1999

27. Bullous 'cellulitis' with eosinophilia: case report and review of Wells' syndrome in childhood

Author

Gilliam, Amy E., Bruckner, Anna L., Howard, Renee M., Lee, Brian P., Wu, Susan, and Frieden, Ilona J.

Subjects
Eosinophilia -- Case studies, Cellulitis -- Case studies, Children -- Health aspects
Abstract

A 1-year-old girl presented with acute onset of edematous erythematous plaques associated with bullae on her extremities and accompanied by peripheral eosinophilia. She was afebrile, and the skin lesions were pruritic but not tender. The patient was treated with intravenously administered antibiotics for presumed cellulitis, without improvement. However, the lesions responded rapidly to systemic steroid therapy. On the basis of lesional morphologic features, peripheral eosinophilia, and cutaneous histopathologic features, a diagnosis of Wells' syndrome was made. Wells' syndrome is extremely rare in childhood, with 27 pediatric cases reported in the literature. Because it is seen so infrequently, there are no specific guidelines for evaluation and management of Wells" syndrome among children. The diagnosis should be considered for children with presumed cellulitis and eosinophilia who fail to respond to antibiotics. Evaluation should include a directed history, physical examination, complete blood count, and stool testing for ova and parasites, to identify potential triggers. Treatment is with systemic steroid therapy unless disease is limited, in which case medium/ high-potency topical steroids may be indicated. If systemic features are prominent or disease is chronic (lasting >6 months), then a referral to hematology/oncology should be considered. URL: www.pediatrics.org/cgi/doi/10.1542/peds.2004-2273; cellulitis, eosinophilia, eosinophilic cellulitis, Wells' syndrome.

Published
2005

29. List of Contributors

Author

Antaya, Richard J., Baselga, Eulalia, Bedwell, Carol, Bellet, Jane Sanders, Bruckner, Anna L., Carder, K. Robin, Cathcart, Shelley D., Chamlin, Sarah L., Chan, Yuin-Chew, Cordoro, Kelly M., Cohen, Bernard A., Cork, Michael J., Danby, Simon G., Diaz, Lucia, Drolet, Beth Ann, Eichenfield, Lawrence F., Fisher, Brian T., Foley, Catherine C., Frieden, Ilona J., Friedlander, Sheila Fallon, Galbraith, Sheila S., Garzon, Maria C., Haggstrom, Anita N., Hand, Jennifer L., Hebert, Adelaide A., Hernández-Martín, Angela, Hoath, Steven B., Honig, Paul J., Howard, Renee M., Hunt, Raegan D., Irvine, Alan D., Jensen, Cynthia B., Kim, Ho Jin, Krafchik, Bernice R., Krol, Alfons L., Lam, Joseph M., Lawley, Leslie P., Levy, Moise L., Lucky, Anne W., Maguiness, Sheilagh M., Mancini, Anthony J., Marghoob, Ashfaq A., Martin, Kari L., Mathes, Erin F., Mauro, Theodora, Morrell, Dean S., O'Regan, Grainne M., Paller, Amy S., Prendiville, Julie S., Price, Harper N., Prose, Neil S., Rubin, Adam I., Schulman, Joshua, Siegel, Dawn H., Silverman, Robert A., Tay, Yong-Kwang, Tom, Wynnis L., Torrelo, Antonio, Treat, James, Williams, Mary L., Wong, Li-Chuen, Yan, Albert C., and Zaenglein, Andrea L.

Published
2015
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30. Childhood Bullous Pemphigoid

Author

Fisler, Rita E., primary, Saeb, Marcela, additional, Liang, Marilyn G., additional, Howard, Renee M., additional, and McKee, Phillip H., additional

Published
2003
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39. Colaboradores

Author

Antaya, Richard J., Baselga, Eulalia, Bernard, Laurie A., Bradley, John S., Bree, Alanna F., Bruckner, Anna L., Burkhart, Craig N., Robin Carder, K., Chan, Yuin-Chew, Chu, David H., Cohen, Bernard A., Cunningham, Bari B., Dinulos, James G.H., Drolet, Beth A., Enjolras, Odile, Friedlander, Sheila Fallon, Galbraith, Sheila S., Garzon, Maria C., Gibbs, Neil F., Gilliam, Amy E., Hebert, Adelaide A., Honig, Paul J., Howard, Renee J., Irvine, Alan D., Kim, Ho Jin, Kos, Liborka, Koss, Tamara, Krafchik, Bernice R., Krol, Alfons L., Lawley, Leslie P., Levy, Moise L., Loomis, Cynthia A., Lucky, Anne W., Makkar, Hanspaul S., Mancini, Anthony J., Metry, Denise W., Metz, Brandie J., Morrell, Dean S., Pace, Nicole C., Paller, Amy S., Prendiville, Julie S., Prose, Neil S., Rogers, Maureen, Siegel, Dawn, Siegfried, Elaine C., Silverman, Robert A., Tay, Yong-Kwang, Torrelo, Antonio, Wagner, Annette M., Williams, Mary L., Wong, Li-Chuen, and Yan, Albert C.

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40. Childhood bullous pemphigoid: a clinicopathologic study and review of the literature.

Author

Fisler RE, Saeb M, Liang MG, Howard RM, and McKee PH

Subjects
Administration, Topical, Blister drug therapy, Blister metabolism, Child, Female, Fluorescent Antibody Technique, Direct, Glucocorticoids therapeutic use, Humans, Immunoenzyme Techniques, Immunoglobulin G metabolism, Infant, Male, Pemphigoid, Bullous drug therapy, Pemphigoid, Bullous metabolism, Treatment Outcome, Blister pathology, Pemphigoid, Bullous pathology
Abstract

Bullous pemphigoid (BP) is an acquired bullous disorder that predominantly affects the elderly. It is rare in children but when it occurs, there is considerable clinical and histologic overlap with other acquired or congenital blistering disorders. A definitive diagnosis of childhood BP requires direct immunofluorescence and, in some cases, characterization of the target antigen. Three cases of childhood BP are presented, with their histologic and immunofluorescence findings. The first was a 5-month-old male infant who presented with erythema and bullae of the palms and soles and was found to have linear deposition of IgG and C3 along the dermoepidermal junction on direct immunofluorescence (DIF). Histopathologic examination revealed a subepidermal blister containing eosinophils. Type IV collagen was demonstrated along the floor of the blister cavity by a direct immunoperoxidase technique. The second case was an 8-month-old female infant who presented with a blistering eruption of her palms and soles that then became widespread. Direct immunofluorescence showed linear IgG and C3 at the dermoepidermal junction, with laminin deposition at the base of the blister. The third case was a 7-year-old female with bullae and erosions on the vulva and vaginal mucosa. A subepidermal blister was seen on microscopic examination whereas immunofluorescence demonstrated linear IgG and C3 deposition at the basement membrane zone (BMZ). A literature review uncovered 50 cases of childhood BP confirmed by direct or indirect immunofluorescence, or both, and often with evidence of autoantibodies against either the 180 kD or the 230 kD human bullous pemphigoid antigens (BP180 or BP230). This review was used to delineate characteristics of childhood BP, including the newly proposed subtypes: infantile BP and childhood localized vulval BP. Infantile BP presents within the first year of life and is characterized by BP-like lesions on erythematous or normal acral skin. Localized vulval BP is a self-limited, nonscarring BP-like process that involves only the vulva. Both subtypes are normally self-limited and respond well to either topical or systemic steroids, if treatment is initiated before the disease becomes widespread.

Published
2003
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