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183 results on '"Houeto, J"'

2. Programming parameters of subthalamic deep brain stimulators in Parkinson's disease from a controlled trial

Author

Knudsen, K., Krack, P., Tonder, L., Houeto, J.-L., Rau, J., Schade-Brittinger, C., Hartmann, A., Hälbig, Thomas D., Paschen, Stephen, Barbe, Michael T., Kühn, Andrea, Fraix, Valerie, Brefel-Courbon, Christine, Vesper, Jan, Maltête, David, Sixel-Döring, Friederike, Weiss, Daniel, Witjas, Tatiana, Thobois, Stephane, Agid, Yves, Schnitzler, A., Schuepbach, W.M.M., Timmermann, L., Damier, Philippe, Vidailhet, M., and Deuschl, G.

Published
2019
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6. Validation of a non-motor fluctuations questionnaire in Parkinson's disease

Author

Faggianelli, F., primary, Loundou, A., additional, Baumstarck, K., additional, Nathalie, S., additional, Auquier, P., additional, Eusebio, A., additional, Defebvre, L., additional, Brefel-Courbon, C., additional, Houeto, J.-L., additional, Maltete, D., additional, Tranchant, C., additional, Derkinderen, P., additional, Geny, C., additional, Krystkowiak, P., additional, Jean-Philippe, B., additional, Macia, F., additional, Durif, F., additional, Poujois, A., additional, Borg, M., additional, Azulay, J.-P., additional, and Witjas, T., additional

Published
2022
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9. Clinical and economic results of bilateral subthalamic nucleus stimulation in Parkinson's disease

Author

Fraix, V, Houeto, J.-L., Lagrange, C., Le Pen, C., Krystkowiak, P., Guehl, D., Ardouin, C., Welter, M.-L., Maurel, F., Defebvre, L., Rougier, A., Benabid, A.-L., Mesnage, V., Ligier, M., Blond, S., Burbaud, P., Bioulac, B., Destee, A., Cornu, P., and Pollak, P.

Subjects
Parkinson's disease -- Care and treatment, Parkinson's disease -- Economic aspects, Neural stimulation -- Patient outcomes, Neural stimulation -- Economic aspects, Thalamus -- Research, Cost benefit analysis -- Research, Cost benefit analysis, Health, Psychology and mental health
Published
2006

10. Neurostimulation for Parkinsonʼs Disease with Early Motor Complications

Author

Schuepbach, W. M.M., Rau, J., Knudsen, K., Volkmann, J., Krack, P., Timmermann, L., Hälbig, T. D., Hesekamp, H., Navarro, S. M., Meier, N., Falk, D., Mehdorn, M., Paschen, S., Maarouf, M., Barbe, M. T., Fink, G. R., Kupsch, A., Gruber, D., Schneider, G. -H., Seigneuret, E., Kistner, A., Chaynes, P., Ory-Magne, F., Courbon, Brefel C., Vesper, J., Schnitzler, A., Wojtecki, L., Houeto, J. -L., Bataille, B., Maltête, D., Damier, P., Raoul, S., Sixel-Doering, F., Hellwig, D., Gharabaghi, A., Krüger, R., Pinsker, M. O., Amtage, F., Régis, J. -M., Witjas, T., Thobois, S., Mertens, P., Kloss, M., Hartmann, A., Oertel, W. H., Post, B., Speelman, H., Agid, Y., Schade-Brittinger, C., and Deuschl, G.

Published
2013
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11. Concurrent excitatory and inhibitory effects of high frequency stimulation: an oculomotor study. (Paper)

Author

Bejjani, B-P., Arnulf, I., Houeto, J-L., Milea, D., Demeret, S., Pidoux, B., Damier, P., Cornu, P., Dormont, D., and Agid, Y.

Subjects
Electric stimulation, Parkinson's disease -- Care and treatment -- Complications and side effects, Health, Psychology and mental health, Care and treatment, Complications and side effects
Abstract

Objective: To describe a reversible neurological condition resembling a crossed midbrain syndrome resulting from high frequency stimulation (HFS) in the midbrain. Methods: Postoperative evaluation of quadripolar electrodes implanted in the [...]

Published
2002

13. Parkinson’s disease with camptocormia

Author

Bloch, F, Houeto, J L, du Montcel, S Tezenas, Bonneville, F, Etchepare, F, Welter, M L, Rivaud-Pechoux, S, Hahn-Barma, V, Maisonobe, T, Behar, C, Lazennec, J Y, Kurys, E, Arnulf, I, Bonnet, A M, and Agid, Y

Published
2006

16. Bilateral deep brain stimulation in Parkinsonʼs disease: a multicentre study with 4 years follow-up

Author

Rodriguez-Oroz, M. C., Obeso, J. A., Lang, A. E., Houeto, J.-L., Pollak, P., Rehncrona, S., Kulisevsky, J., Albanese, A., Volkmann, J., Hariz, M. I., Quinn, N. P., Speelman, J. D., Guridi, J., Zamarbide, I., Gironell, A., Molet, J., Pascual-Sedano, B., Pidoux, B., Bonnet, A. M., Agid, Y., Xie, J., Benabid, A.-L., Lozano, A. M., Saint-Cyr, J., Romito, L., Contarino, M. F., Scerrati, M., Fraix, V., and Van Blercom, N.

Published
2005

17. Tourette’s syndrome and deep brain stimulation

Author

Houeto, J L, Karachi, C, Mallet, L, Pillon, B, Yelnik, J, Mesnage, V, Welter, M L, Navarro, S, Pelissolo, A, Damier, P, Pidoux, B, Dormont, D, Cornu, P, and Agid, Y

Published
2005

26. A Placebo-Controlled Trial of AQW051 in Patients With Moderate to Severe Levodopa-Induced Dyskinesia

Author

Trenkwalder, C, Berg, D, Rascol, O, Eggert, K, Ceballos-Baumann, A, Corvol, J-C, Storch, A, Zhang, L, Azulay, J-P, Broussolle, E, Defebvre, L, Geny, C, Gostkowski, M, Stocchi, F, Tranchant, C, Derkinderen, P, Durif, F, Espay, AJ, Feigin, A, Houeto, J-L, Schwarz, J, Di Paolo, T, Feuerbach, D, Hockey, H-U, Jaeger, J, Jakab, A, Johns, D, Linazasoro, G, Maruff, P, Rozenberg, I, Sovago, J, Weiss, M, Gomez-Mancilla, B, Trenkwalder, C, Berg, D, Rascol, O, Eggert, K, Ceballos-Baumann, A, Corvol, J-C, Storch, A, Zhang, L, Azulay, J-P, Broussolle, E, Defebvre, L, Geny, C, Gostkowski, M, Stocchi, F, Tranchant, C, Derkinderen, P, Durif, F, Espay, AJ, Feigin, A, Houeto, J-L, Schwarz, J, Di Paolo, T, Feuerbach, D, Hockey, H-U, Jaeger, J, Jakab, A, Johns, D, Linazasoro, G, Maruff, P, Rozenberg, I, Sovago, J, Weiss, M, and Gomez-Mancilla, B

Published
2016

28. Optimal target localization for subthalamic stimulation in patients with Parkinson disease

Author

Welter, M.-L., primary, Schupbach, M., additional, Czernecki, V., additional, Karachi, C., additional, Fernandez-Vidal, S., additional, Golmard, J.-L., additional, Serra, G., additional, Navarro, S., additional, Welaratne, A., additional, Hartmann, A., additional, Mesnage, V., additional, Pineau, F., additional, Cornu, P., additional, Pidoux, B., additional, Worbe, Y., additional, Zikos, P., additional, Grabli, D., additional, Galanaud, D., additional, Bonnet, A.-M., additional, Belaid, H., additional, Dormont, D., additional, Vidailhet, M., additional, Mallet, L., additional, Houeto, J.-L., additional, Bardinet, E., additional, Yelnik, J., additional, and Agid, Y., additional

Published
2014
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29. Neurostimulation for Parkinson's disease with early motor complications.

Author

Luxembourg Centre for Systems Biomedicine (LCSB): Clinical & Experimental Neuroscience (Krüger Group) [research center], Schuepbach, W. M. M., Rau, J., Knudsen, K., Volkmann, J., Krack, P., Timmermann, L., Halbig, T. D., Hesekamp, H., Navarro, S. M., Meier, N., Falk, D., Mehdorn, M., Paschen, S., Maarouf, M., Barbe, M. T., Fink, G. R., Kupsch, A., Gruber, D., Schneider, G.-H., Seigneuret, E., Kistner, A., Chaynes, P., Ory-Magne, F., Brefel Courbon, C., Vesper, J., Schnitzler, A., Wojtecki, L., Houeto, J.-L., Bataille, B., Maltete, D., Damier, P., Raoul, S., Sixel-Doering, F., Hellwig, D., Gharabaghi, A., Krüger, Rejko, Pinsker, M. O., Amtage, F., Regis, J.-M., Witjas, T., Thobois, S., Mertens, P., Kloss, M., Hartmann, A., Oertel, W. H., Post, B., Speelman, H., Agid, Y., Schade-Brittinger, C., Deuschl, G., Luxembourg Centre for Systems Biomedicine (LCSB): Clinical & Experimental Neuroscience (Krüger Group) [research center], Schuepbach, W. M. M., Rau, J., Knudsen, K., Volkmann, J., Krack, P., Timmermann, L., Halbig, T. D., Hesekamp, H., Navarro, S. M., Meier, N., Falk, D., Mehdorn, M., Paschen, S., Maarouf, M., Barbe, M. T., Fink, G. R., Kupsch, A., Gruber, D., Schneider, G.-H., Seigneuret, E., Kistner, A., Chaynes, P., Ory-Magne, F., Brefel Courbon, C., Vesper, J., Schnitzler, A., Wojtecki, L., Houeto, J.-L., Bataille, B., Maltete, D., Damier, P., Raoul, S., Sixel-Doering, F., Hellwig, D., Gharabaghi, A., Krüger, Rejko, Pinsker, M. O., Amtage, F., Regis, J.-M., Witjas, T., Thobois, S., Mertens, P., Kloss, M., Hartmann, A., Oertel, W. H., Post, B., Speelman, H., Agid, Y., Schade-Brittinger, C., and Deuschl, G.

Abstract

BACKGROUND: Subthalamic stimulation reduces motor disability and improves quality of life in patients with advanced Parkinson's disease who have severe levodopa-induced motor complications. We hypothesized that neurostimulation would be beneficial at an earlier stage of Parkinson's disease. METHODS: In this 2-year trial, we randomly assigned 251 patients with Parkinson's disease and early motor complications (mean age, 52 years; mean duration of disease, 7.5 years) to undergo neurostimulation plus medical therapy or medical therapy alone. The primary end point was quality of life, as assessed with the use of the Parkinson's Disease Questionnaire (PDQ-39) summary index (with scores ranging from 0 to 100 and higher scores indicating worse function). Major secondary outcomes included parkinsonian motor disability, activities of daily living, levodopa-induced motor complications (as assessed with the use of the Unified Parkinson's Disease Rating Scale, parts III, II, and IV, respectively), and time with good mobility and no dyskinesia. RESULTS: For the primary outcome of quality of life, the mean score for the neurostimulation group improved by 7.8 points, and that for the medical-therapy group worsened by 0.2 points (between-group difference in mean change from baseline to 2 years, 8.0 points; P=0.002). Neurostimulation was superior to medical therapy with respect to motor disability (P<0.001), activities of daily living (P<0.001), levodopa-induced motor complications (P<0.001), and time with good mobility and no dyskinesia (P=0.01). Serious adverse events occurred in 54.8% of the patients in the neurostimulation group and in 44.1% of those in the medical-therapy group. Serious adverse events related to surgical implantation or the neurostimulation device occurred in 17.7% of patients. An expert panel confirmed that medical therapy was consistent with practice guidelines for 96.8% of the patients in the neurostimulation group and for 94.5% of those in the medical-thera

Published
2013

30. Selecting deep brain stimulation or infusion therapies in advanced Parkinson's disease: an evidence-based review

Author

Volkmann, J, Albanese, Alberto, Antonini, A, Chaudhuri, Kr, Clarke, Ce, De Bie, Rma, Deuschl, G, Eggert, K, Houeto, J, Kulisevsky, J, Nyholm, D, Odin, P, Østergaard, K, Poewe, W, Pollak, P, Rabey, Jm, Rascol, O, Ruzicka, E, Samuel, M, Speelman, H, Sydow, O, Valldeoriola, F, Van Der Linden, C, Oertel, W., Albanese, Alberto (ORCID:0000-0002-5864-0006), Volkmann, J, Albanese, Alberto, Antonini, A, Chaudhuri, Kr, Clarke, Ce, De Bie, Rma, Deuschl, G, Eggert, K, Houeto, J, Kulisevsky, J, Nyholm, D, Odin, P, Østergaard, K, Poewe, W, Pollak, P, Rabey, Jm, Rascol, O, Ruzicka, E, Samuel, M, Speelman, H, Sydow, O, Valldeoriola, F, Van Der Linden, C, Oertel, W., and Albanese, Alberto (ORCID:0000-0002-5864-0006)

Abstract

Motor complications in Parkinson's disease (PD) result from the short half-life and irregular plasma fluctuations of oral levodopa. When strategies of providing more continuous dopaminergic stimulation by adjusting oral medication fail, patients may be candidates for one of three device-aided therapies: deep brain stimulation (DBS), continuous subcutaneous apomorphine infusion, or continuous duodenal/jejunal levodopa/carbidopa pump infusion (DLI). These therapies differ in their invasiveness, side-effect profile, and the need for nursing care. So far, very few comparative studies have evaluated the efficacy of the three device-aided therapies for specific motor problems in advanced PD. As a result, neurologists currently lack guidance as to which therapy could be most appropriate for a particular PD patient. A group of experts knowledgeable in all three therapies reviewed the currently available literature for each treatment and identified variables of clinical relevance for choosing one of the three options such as type of motor problems, age, and cognitive and psychiatric status. For each scenario, pragmatic and (if available) evidence-based recommendations are provided as to which patients could be candidates for either DBS, DLI, or subcutaneous apomorphine.

Published
2013

31. Concurrent excitatory and inhibitory effects of high frequency stimulation: an oculomotor study

Author

Bejjani, B, Arnulf, I, Houeto, J, Milea, D, Demeret, S, Pidoux, B, Damier, P, Cornu, P, Dormont, D, and Agid, Y

Subjects
Paper, Male, integumentary system, Eye Movements, Electric Stimulation Therapy, Parkinson Disease, Syndrome, Middle Aged, nervous system, Oculomotor Nerve, Mesencephalon, Subthalamic Nucleus, Humans, Electrodes
Abstract

To describe a reversible neurological condition resembling a crossed midbrain syndrome resulting from high frequency stimulation (HFS) in the midbrain.Postoperative evaluation of quadripolar electrodes implanted in the area of the subthalamic nucleus of 25 patients with Parkinson's disease (PD) successfully treated by HFS.Four of the 25 patients experienced reversible acute diplopia, with dystonic posture and tremor in the contralateral upper limb when the white matter between the red nucleus and the substantia nigra was stimulated. The motor signs resembled those caused by lesions of the red nucleus. The ipsilateral resting eye position was "in and down" (three patients) or "in" (one patient). Enophthalmos was seen. Abduction was impaired and vertical eye movements were limited, but adduction was spared. The movements of the controlateral eye were normal. The ocular signs could be best explained by sustained hyperactivity of the extrinsic oculomotor nerve. Simultaneous tonic contraction of the superior rectus, the inferior rectus, and inferior oblique may cause the enophthalmos and partial limitation of upward and downward eye movements. Antagonist tonic contraction of the ipsilateral medial rectus severely impairs abduction.This crossed midbrain syndrome, possibly resulting from simultaneous activation of oculomotor nerve and lesion-like inhibition of the red nucleus suggests that high frequency stimulation has opposite effects on grey and white matter.

Published
2002

32. Long-term effects of pallidal or subthalamic deep brain stimulation on quality of life in Parkinson's disease

Author

Volkmann, J, Albanese, Alberto, Kulisevsky, J, Tornqvist, A, Houeto, J, Pidoux, B, Bonnet, A, Mendes, A, Benabid, A, Fraix, V, Van Blercom, N, Xie, J, Obeso, J, Rodriguez Oroz, Mc, Guridi, J, Schnitzler, A, Timmermann, L, Gironell, Aa, Molet, J, Pascual Sedano, B, Rehncrona, S, Moro, Ea, Lang, Ac, Lozano, Am, Bentivoglio, Anna Rita, Scerrati, Massimo, Contarino, Maria Fiorella, Romito, L, Janssens, M, Agid, Y., Albanese, Alberto (ORCID:0000-0002-5864-0006), Bentivoglio, Anna Rita (ORCID:0000-0002-9663-095X), Volkmann, J, Albanese, Alberto, Kulisevsky, J, Tornqvist, A, Houeto, J, Pidoux, B, Bonnet, A, Mendes, A, Benabid, A, Fraix, V, Van Blercom, N, Xie, J, Obeso, J, Rodriguez Oroz, Mc, Guridi, J, Schnitzler, A, Timmermann, L, Gironell, Aa, Molet, J, Pascual Sedano, B, Rehncrona, S, Moro, Ea, Lang, Ac, Lozano, Am, Bentivoglio, Anna Rita, Scerrati, Massimo, Contarino, Maria Fiorella, Romito, L, Janssens, M, Agid, Y., Albanese, Alberto (ORCID:0000-0002-5864-0006), and Bentivoglio, Anna Rita (ORCID:0000-0002-9663-095X)

Abstract

We assessed the effects of deep brain stimulation of the subthalamic nucleus (STN-DBS) or internal pallidum (GPi-DBS) on health-related quality of life (HrQoL) in patients with advanced Parkinson's disease participating in a previously reported multicenter trial. Sickness Impact Profile (SIP) questionnaires were available for analysis in a subgroup of n = 20/20 patients with GPi-DBS and n = 45/49 patients with STN-DBS at baseline, 6 and 36 months. The SIP provides a physical dimension and a psychosocial dimension sum score and 12 category scores: Alertness/Intellectual Behavior (AIB), Ambulation (A), Body Care and Movement (BCM), Communication (C), Eating (E), Emotional Behavior (EB), Home Management (HM), Mobility (M), Recreation and Pastimes (RP), Sleep and Rest (SR), Social Interaction (SI), and Work (W). Motor functioning was assessed by means of the Unified Parkinson's Disease Rating Scale and diaries. At 6 months significant improvements in off-period motor symptoms and activities of daily living were paralleled by significant reductions in the total, physical, and psychosocial SIP score in both treatment groups. At 3 years, sustained improvements were observed in the physical dimension score, BCM, E, M, RP after STN-DBS and M, SI after GPi-DBS. All other SIP subscores approached baseline values, but were still the same or better (except C) whereas motor functioning remained stable after 36 months. STN-DBS and GPi-DBS led to significant early improvements in HrQoL. Despite sustained motor improvements many of these initial benefits were lost after 3 years. This may reflect either progression of the disease or adaptive changes in the subjective perception of health-related wellbeing over time.

Published
2009

34. Bilateral deep brain stimulation in Parkinson's disease : a multicentre study with 4 years follow-up.

Author

Rodriguez-Oroz, M C, Obeso, J A, Lang, A E, Houeto, J-L, Pollak, P, Rehncrona, S, Kulisevsky, J, Albanese, A, Volkmann, J, Hariz, M I, Quinn, N P, Speelman, J D, Guridi, J, Zamarbide, I, Gironell, A, Molet, J, Pascual-Sedano, B, Pidoux, B, Bonnet, A M, Agid, Y, Xie, J, Benabid, A-L, Lozano, A M, Saint-Cyr, J, Romito, L, Contarino, M F, Scerrati, M, Fraix, V, Van Blercom, N, Rodriguez-Oroz, M C, Obeso, J A, Lang, A E, Houeto, J-L, Pollak, P, Rehncrona, S, Kulisevsky, J, Albanese, A, Volkmann, J, Hariz, M I, Quinn, N P, Speelman, J D, Guridi, J, Zamarbide, I, Gironell, A, Molet, J, Pascual-Sedano, B, Pidoux, B, Bonnet, A M, Agid, Y, Xie, J, Benabid, A-L, Lozano, A M, Saint-Cyr, J, Romito, L, Contarino, M F, Scerrati, M, Fraix, V, and Van Blercom, N

Published
2005

35. Why Does Bilateral Subthalamic Stimulation Induced Cognitive Decline in Patients with Parkinson's Disease? (S52.005)

Author

Welter, M.-L., primary, Czernecki, V., additional, Schupbach, M., additional, Fernandez-Vidal, S., additional, Karachi, C., additional, Navarro, S., additional, Cornu, P., additional, Pidoux, B., additional, Mallet, L., additional, Dormont, D., additional, Vidailhet, M., additional, Grabli, D., additional, Bonnet, A.-M., additional, Belaid, H., additional, Houeto, J.-L., additional, Bardinet, E., additional, Yelnik, J., additional, and Agid, Y., additional

Published
2012
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36. Why Does Bilateral Subthalamic Stimulation Induced Cognitive Decline in Patients with Parkinson's Disease? (IN6-2.001)

Author

Welter, M.-L., primary, Czernecki, V., additional, Schupbach, M., additional, Fernandez-Vidal, S., additional, Karachi, C., additional, Navarro, S., additional, Cornu, P., additional, Pidoux, B., additional, Mallet, L., additional, Dormont, D., additional, Vidailhet, M., additional, Grabli, D., additional, Bonnet, A.-M., additional, Belaid, H., additional, Houeto, J.-L., additional, Bardinet, E., additional, Yelnik, J., additional, and Agid, Y., additional

Published
2012
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42. Efficacité des effets moteurs et non moteurs de la stimulation pallidale bilatérale dans la dystonie généralisée primaire : trois ans d’évolution

Author

Vidailhet, M., primary, Houeto, J., additional, Vercueil, L., additional, Lagrange, C., additional, Krystkowiak, P., additional, Ardouin, C., additional, Pillon, B., additional, Dujardin, K., additional, Fraix, V., additional, Grabli, D., additional, Welter, M., additional, Benabid, A., additional, Navarro, S., additional, Blond, S., additional, Destée, A., additional, Agid, Y., additional, Yelnik, J., additional, and Pollak, P., additional

Published
2007
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44. Neurosurgery at an earlier stage of Parkinson disease: A randomized, controlled trial

Author

Schupbach, W.M.M., primary, Maltete, D., additional, Houeto, J. L., additional, du Montcel, S. T., additional, Mallet, L., additional, Welter, M. L., additional, Gargiulo, M., additional, Behar, C., additional, Bonnet, A. M., additional, Czernecki, V., additional, Pidoux, B., additional, Navarro, S., additional, Dormont, D., additional, Cornu, P., additional, and Agid, Y., additional

Published
2006
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45. Neurosurgery in Parkinson disease

Author

Schüpbach, M., primary, Gargiulo, M., additional, Welter, M. L., additional, Mallet, L., additional, Béhar, C., additional, Houeto, J. L., additional, Maltête, D., additional, Mesnage, V., additional, and Agid, Y., additional

Published
2006
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46. Parkinson disease, brain volumes, and subthalamic nucleus stimulation

Author

Bonneville, F., primary, Welter, M. L., additional, Elie, C., additional, du Montcel, S. T., additional, Hasboun, D., additional, Menuel, C., additional, Houeto, J. L., additional, Bonnet, A. M., additional, Mesnage, V., additional, Pidoux, B., additional, Navarro, S., additional, Cornu, P., additional, Agid, Y., additional, and Dormont, D., additional

Published
2005
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50. Résultats cliniques et économiques de la stimulation du noyau subthalamique dans la maladie de Parkinson

Author

Fraix, V., primary, Houeto, J.-L., additional, Lagrange, C., additional, Le Pen, C., additional, Krystkowiak, P., additional, Guehl, D., additional, Ardouin, C., additional, Welter, M.-L., additional, Maurel, F., additional, Defebvre, L., additional, Rougier, A., additional, Benabid, A.-L., additional, Mesnage, V., additional, Ligier, M., additional, Blond, S., additional, Burbaud, P., additional, Bioulac, B., additional, Destée, A., additional, Cornu, P., additional, and Pollak, P., additional

Published
2005
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