1. A Specific Assessment of the Normal Anatomy of the Aortic Root in Relation to Age and Gender
- Author
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Wang X, Ren XS, An YQ, Hou ZH, Yu YT, Lu B, and Wang F
- Subjects
aortic root ,bsa ,ccta ,age ,gender ,Medicine (General) ,R5-920 - Abstract
Xiang Wang,1,2 Xin-Shuang Ren,3 Yun-Qiang An,3 Zhi-Hui Hou,3 Yi-Tong Yu,3 Bin Lu,3,* Fang Wang1,2,* 1Department of Cardiology, Beijing Hospital, National Center of Gerontology, Institute of Geriatric Medicine, Chinese Academy of Medical Sciences, Beijing, 100730, People’s Republic of China; 2Graduate School of Peking Union Medical College, Chinese Academy of Medical Science, Beijing, 100730, People’s Republic of China; 3Department of Radiology, Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, 100037, People’s Republic of China*These authors contributed equally to this workCorrespondence: Fang WangDepartment of Cardiology, Beijing Hospital, National Center of Gerontology, Institute of Geriatric Medicine, Chinese Academy of Medical Sciences, No. 1 DaHua Road, Dongcheng District, Beijing, 100730, People’s Republic of ChinaTel +86 10 85132266Email fw_wangdr@163.comBin LuDepartment of Radiology, Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College, No. 167 Bei-Li-Shi Street, Xicheng District, Beijing, 100037, People’s Republic of ChinaTel +86 10 88398700Email binlu_bl09@163.comBackground: A limitation associated with coronary computed tomography angiography (CCTA) is the lack of a normal reference value for aortic root dimensions and the uncertainty of the influence of age and gender on these dimensions. The purpose of the present study was to identify the normal values and variations of aortic root dimensions in healthy individuals and investigate how gender and age affect aortic root size.Methods: A total of 1286 healthy yellow population (52.7 ± 11.0 years, 634 male) who underwent CCTA were retrospectively included in the present study. Male and female patients were divided into seven groups according to age (< 30 years old, 30– 39, 40– 49, 50– 59, 60– 69, 70– 79, ≥ 80 years old). In these age groups, we measured and compared the parameters of the aortic root.Results: After body surface area (BSA) correction, the aortic root parameters of females were found to be greater than those of males in the 40– 49 age group (P< 0.05). There were no significant differences in aortic root parameters between genders in other age groups, except for the diameter of the ascending aorta, which was greater in females (P< 0.05). In males, age was positively correlated with aortic root parameters (P< 0.05), except for the annulus short diameter and LVOT short diameter. In females, age was positively correlated with aortic root parameters (P< 0.05), except for the left coronary ostia height and the LVOT short diameter.Conclusion: Aortic root dimensions are affected by age and gender. After BSA correction, females show larger aortic root dimensions than males, and aortic root diameters increase with age.Keywords: aortic root, BSA, CCTA, age, gender
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- 2021