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7. TYG Index as a Novel Predictor of Clinical Outcomes in Advanced Chronic Heart Failure with Renal Dysfunction Patients

Author

Su, Chang, primary, Wang, Zeyu, additional, Qin, Zhen, additional, Lv, Yan, additional, Hou, Yachen, additional, Zhang, Ge, additional, Cheng, Mengdie, additional, Cui, Xinyue, additional, Liu, Zhiyu, additional, Du, Pengchong, additional, Liu, Tianding, additional, Yuan, Peiyu, additional, Tang, Junnan, additional, and Zhang, Jinying, additional

Published
2024
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8. List of contributors

Author

Aali Mohammadi, Raana, primary, Abate, Molla Tadesse, additional, Abou Elmaaty, Tarek, additional, Adekoya, Mathew Adefusika, additional, Ahmed, Firoz, additional, Ahmed, Mutasim Abdalla, additional, Ahmed, Mohammad Boshir, additional, Ajai, Alex Ikechukwu, additional, Alebeid, Omer Kamal, additional, Alom, Jahangir, additional, Alshehri, Sultan, additional, Alvani, Samira, additional, Alvarado-Ibarra, Juana, additional, Amiri, Saber, additional, Asif, Mohammad, additional, Bataglioli, Rogério Aparecido, additional, Beppu, Marisa Masumi, additional, Bilisik, Kadir, additional, Blaj, Diana Andreea, additional, Burrola-Núñez, Heidy, additional, Cai, Guangming, additional, Cai, Yingjie, additional, Calais, Guilherme Bedeschi, additional, Chandra Dafader, Nirmal, additional, Chauhan, Vinay, additional, Cheng, Deshan, additional, da Silva Júnior, Afonso Henrique, additional, Dondi, Daniele, additional, Ezeanya-Bakpa, Chinyere Charity, additional, Faisal, Ashik Md., additional, Fernandes, Gerson Avelino, additional, Freitas, Emanuelle Dantas de, additional, Gilani, Sadaf Jamal, additional, Hande, Pankaj E., additional, Hasan, Md. Saif, additional, Hasan, K.M. Faridul, additional, Hassan, Elwathig A.M., additional, Hossain, Md. Yousuf, additional, Hou, Yachen, additional, Imam, Syed Sarim, additional, Inobeme, Abel, additional, Islam, Moyinul, additional, Jamalpour, Seifollah, additional, Kala, Chandra, additional, Karaduman, Yekta, additional, Karaduman, Nesrin Sahbaz, additional, Khan, Najam Ali, additional, Kiasat, Alireza, additional, Lawal, Yusuf Babatunde, additional, Li, Jingan, additional, Liu, Xueting, additional, Lopes, Toni Jefferson, additional, Maghsoudian, Ali, additional, Mahmud, Sharif Tasnim, additional, Maity, Subhankar, additional, Martins, Manoel Leonardo, additional, Moaref, Roxana, additional, Moghanjougi, Zahra Motalebi, additional, Mondal, Md. Ibrahim H., additional, Naddeo, Vincenzo, additional, Nam, Sunghyun, additional, Nezamdoost-Sani, Narmin, additional, Nie, Lei, additional, Nitai, Ashis Sutradhar, additional, Nur, Hadi, additional, Okoro, Oseweuba Valentine, additional, Pandit, Pintu, additional, Parham, Shokoh, additional, Peptu, Cristian, additional, Pervez, Md. Nahid, additional, Rahman, Md. Saifur, additional, Rahman, Nazia, additional, Rezazadeh-Bari, Mahmoud, additional, Rosa, Gilber Ricardo, additional, Rotaru, Razvan, additional, Saha, Joykrishna, additional, Samui, Asit Baran, additional, Sayed-Ahmed, Khaled, additional, Scheeren, Carla Weber, additional, Shamsuzzaman, M., additional, Shavandi, Amin, additional, Shirazi, Mahsa, additional, Singha, Kunal, additional, Stylios, George K., additional, Sun, Shaolan, additional, Syduzzaman, Md, additional, Tadesse, Melkie Getnet, additional, Taleuzzaman, Mohamad, additional, Talukder, Md. Eman, additional, Tamsilian, Yousef, additional, Tang, Xiaoning, additional, Tong, Peiduo, additional, Vadivel, Dhanalakshmi, additional, Xue, Zhonghua, additional, Yang, Ningning, additional, Zargar Kharazi, Anousheh, additional, Zhang, Xueqi, additional, Zhang, Shangyong, additional, and Zhu, Shu, additional

Published
2022
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11. TYG Index as a Novel Predictor of Clinical Outcomes in Advanced Chronic Heart Failure with Renal Dysfunction Patients

Author

Su,Chang, Wang,Zeyu, Qin,Zhen, Lv,Yan, Hou,Yachen, Zhang,Ge, Cheng,Mengdie, Cui,Xinyue, Liu,Zhiyu, Du,Pengchong, Liu,Tianding, Yuan,Peiyu, Tang,Junnan, Zhang,Jinying, Su,Chang, Wang,Zeyu, Qin,Zhen, Lv,Yan, Hou,Yachen, Zhang,Ge, Cheng,Mengdie, Cui,Xinyue, Liu,Zhiyu, Du,Pengchong, Liu,Tianding, Yuan,Peiyu, Tang,Junnan, and Zhang,Jinying

Abstract

Chang Su,1– 3 Zeyu Wang,4 Zhen Qin,1– 3 Yan Lv,1– 3 Yachen Hou,1– 3 Ge Zhang,1– 3 Mengdie Cheng,1– 3 Xinyue Cui,1– 3 Zhiyu Liu,1– 3 Pengchong Du,1– 3 Tianding Liu,1– 3 Peiyu Yuan,1– 3 Junnan Tang,1– 3 Jinying Zhang1– 3 1Department of Cardiology, First Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan, People’s Republic of China; 2Key Laboratory of Cardiac Injury and Repair of Henan Province, Zhengzhou, Henan, People’s Republic of China; 3Henan Province Clinical Research Center for Cardiovascular Diseases, Zhengzhou, Henan, People’s Republic of China; 4Department of Cardiology, Fuwai Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, People’s Republic of ChinaCorrespondence: Junnan Tang; Jinying Zhang, Department of Cardiology, First Affiliated Hospital of Zhengzhou University, No. 1 Eastern Jianshe Road, Zhengzhou, Henan, 450052, People’s Republic of China, Tel +86 15890696166 ; +86 13503830283, Email fcctangjn@zzu.edu.cn; jyzhang@zzu.edu.cnBackground: The triglyceride-glucose (TYG) index is a novel and reliable marker reflecting insulin resistance. Its predictive ability for cardiovascular disease onset and prognosis has been confirmed. However, for advanced chronic heart failure (acHF) patients, the prognostic value of TYG is challenged due to the often accompanying renal dysfunction (RD). Therefore, this study focuses on patients with aHF accompanied by RD to investigate the predictive value of the TYG index for their prognosis.Methods and Results: 717 acHF with RD patients were included. The acHF diagnosis was based on the 2021 ESC criteria for acHF. RD was defined as the eGFR < 90 mL/(min/1.73 m2). Patients were divided into two groups based on their TYG index values. The primary endpoint was major adverse cardiovascular events (MACEs), and the secondary endpoints is all-cause mortality (ACM). The follow-up duration was 21.58 (17.98– 25.39) months. The optimal cutoff valu

Published
2024

17. Current Topics in Medicine and Medical Research Vol. 5

Author

Mirza, Saqeb B., additional, Shah, Nirav N., additional, Edres, Abdelhakim Kareem, additional, Abdelghafour, Karim M., additional, Panesar, Sukhmeet S., additional, Kothari, J. V., additional, Patel, R. D., additional, Chaurasiya, A., additional, Solanki, Atul, additional, Thosani, R. M., additional, Fayadh, Makki H., additional, Sabih, Salem Awadh, additional, Quadri, Hadi Affan, additional, Eladawei, Ghada Ezzat, additional, Abdellatif, Rasha Mohamed, additional, El-Taher, Sheref Mohamed, additional, Vieira, Ricardo Parente Garcia, additional, Júnior, Jucier Gonçalves, additional, Leite, Acácio Vieira Machado, additional, Pereira, Viviane Chaves, additional, Vieira, Nélio Barreto, additional, Rolim-Neto, Modesto Leite, additional, Rahman, Asifur, additional, Asif, Dewan Shamsul, additional, Bhandari, Paawan Bahadur, additional, Hossain, S. K. Sader, additional, Zope, Mukesh, additional, Patil, Deepali, additional, Kuriakose, Angel, additional, Aslam, P. A., additional, George, Basil, additional, Mandal, Abhijit, additional, Kwaji, A., additional, Bassi, P. U., additional, Aoill, M., additional, Nneji, C. M., additional, Ademowo, G., additional, Trivedi, Vinita, additional, Khan, Ali Nawaz, additional, Keshri, Shekhar Kumar, additional, Uzoka, Ken, additional, Macdonald, Sumaira, additional, Hammond, Abeeku Afedzi, additional, Venyo, Anthony Kodzo-Grey, additional, Almandlawi, Sanaa Gadbaan Hama, additional, Mawlood, Muhanad Salah, additional, Wang, Kelin, additional, Shoutko, Aleksey N., additional, Mus, Victor F., additional, Maystrenko, Dmitry N., additional, Li, Jingan, additional, Zhang, Kun, additional, Hou, Yachen, additional, Benharroch, Daniel, additional, and Benharroch, Assaf, additional

Published
2020
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24. Antibacterial Activity of Squaric Amide Derivative SA2 against Methicillin-Resistant Staphylococcus aureus

Author

Yu, Moxi, primary, Hou, Yachen, additional, Cheng, Meiling, additional, Liu, Yongshen, additional, Ling, Caise, additional, Zhai, Dongshen, additional, Zhao, Hui, additional, Li, Yaoyao, additional, Chen, Yamiao, additional, Xue, Xiaoyan, additional, Ma, Xue, additional, Jia, Min, additional, Wang, Bin, additional, Wang, Pingan, additional, and Li, Mingkai, additional

Published
2022
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27. Atherosclerosis: The Involvement of Immunity, Cytokines and Cells in Pathogenesis, and Potential Novel Therapeutics

Author

Su, Chang, primary, Lu, Yongzheng, primary, Wang, Zeyu, primary, Guo, Jiacheng, primary, Hou, Yachen, primary, Wang, Xiaofang, primary, Qin, Zhen, primary, Gao, Jiamin, primary, Sun, Zhaowei, primary, Dai, Yichen, primary, Liu, Yu, primary, Liu, Guozhen, primary, Xian, Xunde, primary, Cui, Xiaolin, primary, Zhang, Jinying, primary, and Tang, Junnan, primary

Published
2022
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32. Contributors

Author

Ahirwar, Jyoti, Aquinas, Natasha, Aytekin, Ali Özhan, Badwaik, Hemant Ramachandra, Barik, Anwesha, Bhat M, Ramananda, Cassano, Roberta, Curcio, Federica, Dangre, Pankaj V., Debnath, Sujit Kumar, Debnath, Monalisha, Dey, Sanjay, Du, Guoxin, Dutta, Pallobi, Fang, Jinzhang, Ghosh, Bijaya, Giri, Tapan Kumar, González-Garcinuño, Álvaro, Grigoras, Anca Giorgiana, Gurumukhi, Vishal C., Hou, Yachen, Kahali, Nancy, Kayra, Neslihan, Kirtania, Moumita Das, Kirtania, Ranjan, Kumari, Leena, Li, Jingan, Liang, Bo, Martín del Valle, Eva M., Meshram, Satish S., Mukherjee, Kaushik, Omri, Abdelwahab, Pan, Yijun, Peng, Haizhou, Sakure, Kalyani, Selvaraj, Subbalaxmi, Sole, Roberta, Sonkar, Sandeep Kumar, Srivastava, Rohit, Tabernero, Antonio, Tatke, Akshaya, Thakur, Amrita, Trombino, Sonia, Verma, Vinay Sagar, Zade, Sankalp M., and Zhu, Jieyu

Published
2024
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33. Atherosclerosis: The Involvement of Immunity, Cytokines and Cells in Pathogenesis, and Potential Novel Therapeutics.

Author

Su C, Lu Y, Wang Z, Guo J, Hou Y, Wang X, Qin Z, Gao J, Sun Z, Dai Y, Liu Y, Liu G, Xian X, Cui X, Zhang J, and Tang J

Abstract

As a leading contributor to coronary artery disease (CAD) and stroke, atherosclerosis has become one of the major cardiovascular diseases (CVD) negatively impacting patients worldwide. The endothelial injury is considered to be the initial step of the development of atherosclerosis, resulting in immune cell migration and activation as well as inflammatory factor secretion, which further leads to acute and chronic inflammation. In addition, the inflammation and lipid accumulation at the lesions stimulate specific responses from different types of cells, contributing to the pathological progression of atherosclerosis. As a result, recent studies have focused on using molecular biological approaches such as gene editing and nanotechnology to mediate cellular response during atherosclerotic development for therapeutic purposes. In this review, we systematically discuss inflammatory pathogenesis during the development of atherosclerosis from a cellular level with a focus on the blood cells, including all types of immune cells, together with crucial cells within the blood vessel, such as smooth muscle cells and endothelial cells. In addition, the latest progression of molecular-cellular based therapy for atherosclerosis is also discussed. We hope this review article could be beneficial for the clinical management of atherosclerosis.

Published
2023
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