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184 results on '"Hou, Pingping"'

3. Targeting T cell checkpoints 41BB and LAG3 and myeloid cell CXCR1/CXCR2 results in antitumor immunity and durable response in pancreatic cancer

Author

Gulhati, Pat, Schalck, Aislyn, Jiang, Shan, Shang, Xiaoying, Wu, Chang-Jiun, Hou, Pingping, Ruiz, Sharia Hernandez, Soto, Luisa Solis, Parra, Edwin, Ying, Haoqiang, Han, Jincheng, Dey, Prasenjit, Li, Jun, Deng, Pingna, Sei, Emi, Maeda, Dean Y., Zebala, John A., Spring, Denise J., Kim, Michael, Wang, Huamin, Maitra, Anirban, Moore, Dirk, Clise-Dwyer, Karen, Wang, Y. Alan, Navin, Nicholas E., and DePinho, Ronald A.

Published
2023
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13. Tourism Constraints and Subjective Well-Being for Senior: A Serial Multiple Mediation Model.

Author

Hou, Pingping and Li, Yin

Subjects
*SUBJECTIVE well-being (Psychology), *TOURISM impact, *TOURISM, *WELL-being
Abstract

This study targets seniors aged 60 and above, exploring the impact of tourism constraints on their subjective well-being through the lens of Activity Theory, as well as the mediating and serial mediating roles played by constraint negotiation and tourism participation. Conducted through a questionnaire survey, the empirical research reveals that tourism constraints negatively impact the subjective well-being of seniors. Conversely, tourism constraints positively influence constraint negotiation, which in turn positively affects tourism participation. Tourism participation enhances subjective well-being. Furthermore, constraint negotiation acts as a mediator in the relationship between tourism constraints and tourism participation, while tourism participation mediates the relationship between tourism constraints and subjective well-being. Serial mediating effect is found between tourism constraints and subjective well-being through constraint negotiation and tourism participation. This paper enriches the study of outcome variables and mechanisms of elderly tourism constraints, offering targeted suggestions to improve the tourism participation of seniors, thereby enhancing their sense of achievement and well-being. [ABSTRACT FROM AUTHOR]

Published
2024
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14. Exploring Market Credit Evaluation System of Tourism Enterprises from Tourist Perspective.

Author

Hou, Pingping, Li, Yin, and Yan, Jin

Abstract

This study employs literature review and expert consultation methods to construct dimensions and items for evaluating the market credit of tourism enterprises from tourist perspective. A Hierarchical Analysis Method was used to develop the market credit evaluation system for tourism enterprises. The research findings indicate that the evaluation system comprises 7 dimensions and 37 items, which include: credit capacity, credit regulation, credit foundation, credit behavior, economic credit, employee credit, and integrity culture. The Hierarchical Analysis Method was applied to determine the weight for these dimensions and items. The credit foundation of tourism enterprises was found to have the highest weight, followed by credit regulation, credit capacity, credit behavior, economic credit, employee credit, and integrity culture. Theoretically, this research enriches the theory of tourism enterprise credit and provides a measurement tool for evaluating market credit. Practically, it offers targeted suggestions and strategies for tourism enterprises to enhance their market credit. [ABSTRACT FROM AUTHOR]

Published
2024
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15. Design, Preparation, and Interfacial Adhesion of Polystyrene‐Based Luminophore Elastomers Based on Bionic Strategy.

Author

Hou, Pingping, Zhao, Chunbao, Hu, Mengxin, Zhang, Jun, Liu, Jiqi, Qian, Zheng, and Ran, Qianping

Subjects
*NUCLEAR magnetic resonance spectroscopy, *EMISSION spectroscopy, *BIONICS, *GEL permeation chromatography, *ULTRAVIOLET-visible spectroscopy, *ELASTOMERS, *CATECHOL
Abstract

A series of rigid polystyrene‐based photoelastomers, named sty‐PM‐x, with bionic catechol pendants were synthesized through atom transfer radical polymerization (ATRP) and deprotection techniques. These polymers were characterized using nuclear magnetic resonance spectroscopy, gel permeation chromatography, and thermogravimetric analysis. Additionally, photophysical properties of the polymers were investigated using UV‐visible absorption spectroscopy and fluorescence emission spectroscopy. Mechanical properties were evaluated through tensile tests, while interfacial adhesion was determined through cross‐cut tests. Experimental results reveal that photoelastomers, sty‐PM‐x, exhibit excellent photophysical properties, stretchability, and interfacial adhesion. This discovery provides a new perspective for the preparation of stretchable organic electroluminescent materials. [ABSTRACT FROM AUTHOR]

Published
2024
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22. Syndecan 1 is a critical mediator of macropinocytosis in pancreatic cancer

Author

Yao, Wantong, Rose, Johnathon L., Wang, Wei, Seth, Sahil, Jiang, Hong, Taguchi, Ayumu, Liu, Jintan, Yan, Liang, Kapoor, Avnish, Hou, Pingping, Chen, Ziheng, Wang, Qiuyun, Nezi, Luigi, Xu, Zhaohui, Yao, Jun, Hu, Baoli, Pettazzoni, Piergiorgio F., Ho, I Lin, Feng, Ningping, Ramamoorthy, Vandhana, Jiang, Shan, Deng, Pingna, Ma, Grace J., Den, Peter, Tan, Zhi, Zhang, Shu Xing, Wang, Huamin, Wang, Y. Alan, Deem, Angela K., Fleming, Jason B., Carugo, Alessandro, Heffernan, Timothy P., Maitra, Anirban, Viale, Andrea, Ying, Haoqiang, Hanash, Samir, DePinho, Ronald A., and Draetta, Giulio F.

Published
2019
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24. Telomere dysfunction activates YAP1 to drive tissue inflammation

Author

Chakravarti, Deepavali, Hu, Baoli, Mao, Xizeng, Rashid, Asif, Li, Jiexi, Li, Jun, Liao, Wen-ting, Whitley, Elizabeth M., Dey, Prasenjit, Hou, Pingping, LaBella, Kyle A., Chang, Andrew, Wang, Guocan, Spring, Denise J., Deng, Pingna, Zhao, Di, Liang, Xin, Lan, Zhengdao, Lin, Yiyun, Sarkar, Sharmistha, Terranova, Christopher, Deribe, Yonathan Lissanu, Blutt, Sarah E., Okhuysen, Pablo, Zhang, Jianhua, Vilar, Eduardo, Nielsen, Ole Haagen, Dupont, Andrew, Younes, Mamoun, Patel, Kalyani R., Shroyer, Noah F., Rai, Kunal, Estes, Mary K., Wang, Y. Alan, Bertuch, Alison A., and DePinho, Ronald A.

Published
2020
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25. Data from Targeting YAP-Dependent MDSC Infiltration Impairs Tumor Progression

Author

Wang, Guocan, primary, Lu, Xin, primary, Dey, Prasenjit, primary, Deng, Pingna, primary, Wu, Chia Chin, primary, Jiang, Shan, primary, Fang, Zhuangna, primary, Zhao, Kun, primary, Konaparthi, Ramakrishna, primary, Hua, Sujun, primary, Zhang, Jianhua, primary, Li-Ning-Tapia, Elsa M., primary, Kapoor, Avnish, primary, Wu, Chang-Jiun, primary, Patel, Neelay Bhaskar, primary, Guo, Zhenglin, primary, Ramamoorthy, Vandhana, primary, Tieu, Trang N., primary, Heffernan, Tim, primary, Zhao, Di, primary, Shang, Xiaoying, primary, Khadka, Sunada, primary, Hou, Pingping, primary, Hu, Baoli, primary, Jin, Eun-Jung, primary, Yao, Wantong, primary, Pan, Xiaolu, primary, Ding, Zhihu, primary, Shi, Yanxia, primary, Li, Liren, primary, Chang, Qing, primary, Troncoso, Patricia, primary, Logothetis, Christopher J., primary, McArthur, Mark J., primary, Chin, Lynda, primary, Wang, Y. Alan, primary, and DePinho, Ronald A., primary

Published
2023
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26. Supplementary Methods, Figure Legends, Figures S1 - S7 from Targeting YAP-Dependent MDSC Infiltration Impairs Tumor Progression

Author

Wang, Guocan, primary, Lu, Xin, primary, Dey, Prasenjit, primary, Deng, Pingna, primary, Wu, Chia Chin, primary, Jiang, Shan, primary, Fang, Zhuangna, primary, Zhao, Kun, primary, Konaparthi, Ramakrishna, primary, Hua, Sujun, primary, Zhang, Jianhua, primary, Li-Ning-Tapia, Elsa M., primary, Kapoor, Avnish, primary, Wu, Chang-Jiun, primary, Patel, Neelay Bhaskar, primary, Guo, Zhenglin, primary, Ramamoorthy, Vandhana, primary, Tieu, Trang N., primary, Heffernan, Tim, primary, Zhao, Di, primary, Shang, Xiaoying, primary, Khadka, Sunada, primary, Hou, Pingping, primary, Hu, Baoli, primary, Jin, Eun-Jung, primary, Yao, Wantong, primary, Pan, Xiaolu, primary, Ding, Zhihu, primary, Shi, Yanxia, primary, Li, Liren, primary, Chang, Qing, primary, Troncoso, Patricia, primary, Logothetis, Christopher J., primary, McArthur, Mark J., primary, Chin, Lynda, primary, Wang, Y. Alan, primary, and DePinho, Ronald A., primary

Published
2023
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27. Supplementary Figures S1-9 from Tumor Microenvironment Remodeling Enables Bypass of Oncogenic KRAS Dependency in Pancreatic Cancer

Author

Hou, Pingping, primary, Kapoor, Avnish, primary, Zhang, Qiang, primary, Li, Jiexi, primary, Wu, Chang-Jiun, primary, Li, Jun, primary, Lan, Zhengdao, primary, Tang, Ming, primary, Ma, Xingdi, primary, Ackroyd, Jeffrey J., primary, Kalluri, Raghu, primary, Zhang, Jianhua, primary, Jiang, Shan, primary, Spring, Denise J., primary, Wang, Y. Alan, primary, and DePinho, Ronald A., primary

Published
2023
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28. Supplementary Table S7 from Targeting YAP-Dependent MDSC Infiltration Impairs Tumor Progression

Author

Wang, Guocan, primary, Lu, Xin, primary, Dey, Prasenjit, primary, Deng, Pingna, primary, Wu, Chia Chin, primary, Jiang, Shan, primary, Fang, Zhuangna, primary, Zhao, Kun, primary, Konaparthi, Ramakrishna, primary, Hua, Sujun, primary, Zhang, Jianhua, primary, Li-Ning-Tapia, Elsa M., primary, Kapoor, Avnish, primary, Wu, Chang-Jiun, primary, Patel, Neelay Bhaskar, primary, Guo, Zhenglin, primary, Ramamoorthy, Vandhana, primary, Tieu, Trang N., primary, Heffernan, Tim, primary, Zhao, Di, primary, Shang, Xiaoying, primary, Khadka, Sunada, primary, Hou, Pingping, primary, Hu, Baoli, primary, Jin, Eun-Jung, primary, Yao, Wantong, primary, Pan, Xiaolu, primary, Ding, Zhihu, primary, Shi, Yanxia, primary, Li, Liren, primary, Chang, Qing, primary, Troncoso, Patricia, primary, Logothetis, Christopher J., primary, McArthur, Mark J., primary, Chin, Lynda, primary, Wang, Y. Alan, primary, and DePinho, Ronald A., primary

Published
2023
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29. Supplementary Table S1 from Tumor Microenvironment Remodeling Enables Bypass of Oncogenic KRAS Dependency in Pancreatic Cancer

Author

Hou, Pingping, primary, Kapoor, Avnish, primary, Zhang, Qiang, primary, Li, Jiexi, primary, Wu, Chang-Jiun, primary, Li, Jun, primary, Lan, Zhengdao, primary, Tang, Ming, primary, Ma, Xingdi, primary, Ackroyd, Jeffrey J., primary, Kalluri, Raghu, primary, Zhang, Jianhua, primary, Jiang, Shan, primary, Spring, Denise J., primary, Wang, Y. Alan, primary, and DePinho, Ronald A., primary

Published
2023
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30. Data from Tumor Microenvironment Remodeling Enables Bypass of Oncogenic KRAS Dependency in Pancreatic Cancer

Author

Hou, Pingping, primary, Kapoor, Avnish, primary, Zhang, Qiang, primary, Li, Jiexi, primary, Wu, Chang-Jiun, primary, Li, Jun, primary, Lan, Zhengdao, primary, Tang, Ming, primary, Ma, Xingdi, primary, Ackroyd, Jeffrey J., primary, Kalluri, Raghu, primary, Zhang, Jianhua, primary, Jiang, Shan, primary, Spring, Denise J., primary, Wang, Y. Alan, primary, and DePinho, Ronald A., primary

Published
2023
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32. Analysis of the Formation Mechanism of Medium and Low-Temperature Geothermal Water in Wuhan Based on Hydrochemical Characteristics

Author

Yin, Zhibin, primary, Li, Xuan, additional, Huang, Changsheng, additional, Chen, Wei, additional, Hou, Baoquan, additional, Li, Xiaozhe, additional, Han, Wenjing, additional, Hou, Pingping, additional, Han, Jihong, additional, Ren, Chonghe, additional, Zou, Jin, additional, Hua, Shan, additional, Xu, Liansan, additional, and Zhao, Ziliang, additional

Published
2023
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33. Targeting T cell checkpoints 41BB and LAG3 and myeloid cell CXCR1/CXCR2 results in antitumor immunity and durable response in pancreatic cancer

Author

Gulhati, Pat, primary, Schalck, Aislyn, additional, Jiang, Shan, additional, Shang, Xiaoying, additional, Wu, Chang-Jiun, additional, Hou, Pingping, additional, Ruiz, Sharia Hernandez, additional, Soto, Luisa Solis, additional, Parra, Edwin, additional, Ying, Haoqiang, additional, Han, Jincheng, additional, Dey, Prasenjit, additional, Li, Jun, additional, Deng, Pingna, additional, Sei, Emi, additional, Maeda, Dean Y., additional, Zebala, John A., additional, Spring, Denise J., additional, Kim, Michael, additional, Wang, Huamin, additional, Maitra, Anirban, additional, Moore, Dirk, additional, Clise-Dwyer, Karen, additional, Wang, Y. Alan, additional, Navin, Nicholas E., additional, and DePinho, Ronald A., additional

Published
2022
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37. Yap1 Hydroxylation Suppress Prostate Cancer Metastasis

Author

Zhu, Ming, primary, Peng, Ruiqing, additional, Liang, Xin, additional, Lan, Zhengdao, additional, Tang, Meng, additional, Hou, Pingping, additional, Song, Jian H., additional, Ling Mak, Celia Sze, additional, Park, Jiwon, additional, Zheng, Shui-Er, additional, Huang, Ailing, additional, Ma, Xingdi, additional, Chen, Ruidong, additional, Chang, Qing, additional, Logothetis, Christopher J., additional, Jain, Abhinav K., additional, Lin, Sue-Hwa, additional, Katayama, Hiroyuki, additional, Hanash, Samir, additional, and Wang, Guocan, additional

Published
2022
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40. USP21 deubiquitinase elevates macropinocytosis to enable oncogenic KRAS bypass in pancreatic cancer

Author

Hou, Pingping, primary, Ma, Xingdi, additional, Yang, Zecheng, additional, Zhang, Qiang, additional, Wu, Chang-Jiun, additional, Li, Jun, additional, Tan, Lin, additional, Yao, Wantong, additional, Yan, Liang, additional, Zhou, Xin, additional, Kimmelman, Alec C., additional, Lorenzi, Philip L., additional, Zhang, Jianhua, additional, Jiang, Shan, additional, Spring, Denise, additional, Wang, Y. Alan, additional, and DePinho, Ronald A., additional

Published
2021
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41. Hypolipidemic activity of low-cholesterol ovum oil of Rana chensinensis and phytosterol (stigmasterol) in rats

Author

Hou Pingping, Chunyu Xi, Tiehua Zhang, Changhui Zhao, Zheng-Ping Zou, Haiqing Ye, Chao Zhao, and Xin-Hui Zhou

Subjects
Male, 0301 basic medicine, Ranidae, Rana chensinensis, Stigmasterol, Hyperlipidemias, General Biochemistry, Genetics and Molecular Biology, Rats, Sprague-Dawley, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Correspondence, Hyperlipidemia, medicine, Animals, General Pharmacology, Toxicology and Pharmaceutics, Ovum, General Veterinary, biology, Traditional medicine, Chemistry, Phytosterol, General Medicine, biology.organism_classification, medicine.disease, Lipids, Rats, Cholesterol, 030104 developmental biology, 030220 oncology & carcinogenesis, Fatty Acids, Unsaturated, Low cholesterol, Female, Oils
Abstract

The ovum oil of forest frog has various health beneficial functions. In the current research, we evaluated the hypolipidemic effects of the low-cholesterol ovum oil from the forest frog and its combination with stigmasterol in rats.

Published
2019

46. NFAT5 governs cellular plasticity-driven resistance to KRAS-targeted therapy in pancreatic cancer

Author

Deng, Daiyong, Begum, Habeebunnisa, Liu, Tong, Zhang, Jiangyan, Zhang, Qiang, Chu, Ting-yu, Li, Hong, Lemenze, Alexander, Hoque, Mainul, Soteropoulos, Patricia, and Hou, Pingping

Abstract

Resistance to KRAS therapy in pancreatic ductal adenocarcinoma (PDAC) involves cellular plasticity, particularly the epithelial-to-mesenchymal transition (EMT), which poses challenges for effective targeting. Chronic pancreatitis, a known risk factor for PDAC, elevates TGFβ levels in the tumor microenvironment (TME), promoting resistance to KRAS therapy. Mechanistically, TGFβ induces the formation of a novel protein complex composed of SMAD3, SMAD4, and the nuclear factor NFAT5, triggering EMT and resistance by activating key mediators such as S100A4. Inhibiting NFAT5 attenuates pancreatitis-induced resistance to KRAS inhibition and extends mouse survival. Additionally, TGFβ stimulates PDAC cells to secrete CCL2, recruiting macrophages that contribute to KRAS bypass through paracrine S100A4. Our findings elucidate the role of TGFβ signaling in EMT-associated KRAS therapy resistance and identify NFAT5 as a druggable target. Targeting NFAT5 could disrupt this regulatory network, offering a potential avenue for preventing resistance in PDAC.

Published
2024
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47. P4HA2-induced prolyl hydroxylation suppresses YAP1-mediated prostate cancer cell migration, invasion, and metastasis

Author

Zhu, Ming, primary, Peng, Ruiqing, additional, Liang, Xin, additional, Lan, Zhengdao, additional, Tang, Ming, additional, Hou, Pingping, additional, Song, Jian H., additional, Mak, Celia Sze Ling, additional, Park, Jiwon, additional, Zheng, Shui-er, additional, Huang, Ailing, additional, Ma, Xingdi, additional, Chen, Ruidong, additional, Chang, Qing, additional, Logothetis, Christopher J., additional, Jain, Abhinav K., additional, Lin, Sue-Hwa, additional, Katayama, Hiroyuki, additional, Hanash, Samir M., additional, and Wang, Guocan, additional

Published
2021
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49. Abstract IA24: YAP in cancer and inflammation

Author

Wang, Guocan, primary, Lu, Xin, additional, Chakravarti, Deepavali, additional, Kapoor, Avnish, additional, Yao, Wantong, additional, Ying, Haoqiang, additional, Dey, Prasenjit, additional, Wu, Chiachin, additional, Spring, Denise, additional, Hou, Pingping, additional, Deng, Pingna, additional, Zhao, Di, additional, Hu, Baoli, additional, Xizeng, Mao, additional, Logothesis, Christopher, additional, McArthur, Michael, additional, Chin, Lynda, additional, Wang, Alan, additional, Hua, Sujun, additional, Xia, Hongai, additional, Chu, Gerald C, additional, Lim, Carol, additional, Vilar, Eduardo, additional, Blutt, Sarah, additional, and DePinho, Ronald A., additional

Published
2020
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50. Tumor Microenvironment Remodeling Enables Bypass of Oncogenic KRAS Dependency in Pancreatic Cancer

Author

Hou, Pingping, primary, Kapoor, Avnish, additional, Zhang, Qiang, additional, Li, Jiexi, additional, Wu, Chang-Jiun, additional, Li, Jun, additional, Lan, Zhengdao, additional, Tang, Ming, additional, Ma, Xingdi, additional, Ackroyd, Jeffrey J., additional, Kalluri, Raghu, additional, Zhang, Jianhua, additional, Jiang, Shan, additional, Spring, Denise J., additional, Wang, Y. Alan, additional, and DePinho, Ronald A., additional

Published
2020
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