223 results on '"Hou, Ming-Hon"'
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2. Antiviral effect of the viroporin inhibitors against Taiwan isolates of infectious bronchitis virus (IBV)
3. Targeting protein-protein interaction interfaces with antiviral N protein inhibitor in SARS-CoV-2
4. Structural basis for water modulating RNA duplex formation in the CUG repeats of myotonic dystrophy type 1
5. Revisiting recent unusual drug-DNA complex structures: Implications for cancer and neurological disease diagnostics and therapeutics
6. Targeting protein-protein interaction interfaces in COVID-19 drug discovery
7. Targeting DNA junction sites by bis-intercalators induces topological changes with potent antitumor effects.
8. Structural basis of water-mediated cis Watson–Crick/Hoogsteen base-pair formation in non-CpG methylation.
9. Antiviral Effect of the Viroporin Inhibitors Against Taiwan Isolates of Infectious Bronchitis Virus (Ibv)
10. Parity-dependent hairpin configurations of repetitive DNA sequence promote slippage associated with DNA expansion
11. Developing a machine-learning model for real-time prediction of successful extubation in mechanically ventilated patients using time-series ventilator-derived parameters
12. Editorial: Non-canonical nucleic acid structures, functions and their applications for understanding human genetic diseases
13. Synergistic binding of actinomycin D and echinomycin to DNA mismatch sites and their combined anti-tumour effects
14. Recent insights into the development of therapeutics against coronavirus diseases by targeting N protein
15. Chapter 6. Binding of Small Molecules to Trinucleotide DNA Repeats Associated with Neurodegenerative Diseases
16. Corrigendum: Targeting the N-terminus domain of the coronavirus nucleocapsid protein induces abnormal oligomerization via allosteric modulation
17. The SARS coronavirus nucleocapsid protein – Forms and functions
18. Staggered intercalation of DNA duplexes with base-pair modulation by two distinct drug molecules induces asymmetric backbone twisting and structure polymorphism
19. Crystal structure-based exploration of the important role of Arg106 in the RNA-binding domain of human coronavirus OC43 nucleocapsid protein
20. The binding of the Co(II) complex of dimeric chromomycin A3 to GC sites with flanking G:G mismatches
21. Evolution of infectious bronchitis virus in Taiwan: Positively selected sites in the nucleocapsid protein and their effects on RNA-binding activity
22. Immunoreactivity characterisation of the three structural regions of the human coronavirus OC43 nucleocapsid protein by Western blot: Implications for the diagnosis of coronavirus infection
23. The effects of loop size on Sac7d-hairpin DNA interactions
24. Targeting the N-Terminus Domain of the Coronavirus Nucleocapsid Protein Induces Abnormal Oligomerization via Allosteric Modulation
25. Video-Assisted Thoracoscopic Surgery in Community-Acquired Thoracic Empyema: Analysis of Risk Factors for Mortality
26. Evolution of infectious bronchitis virus in Taiwan: Characterisation of RNA recombination in the nucleocapsid gene
27. The impact of spermine competition on the efficacy of DNA-binding Fe(II), Co(II), and Cu(II) complexes of dimeric chromomycin A 3
28. Elucidation of the DNA-interacting properties and anticancer activity of a Ni(II)-coordinated mithramycin dimer complex
29. Discovery of Oral Anticancer 1,2-Bis(hydroxymethyl)benzo[g]pyrrolo[2,1-a]phthalazine Hybrids That Inhibit Angiogenesis and Induce DNA Cross-Links
30. Targeting protein-protein interaction interfaces in COVID-19 drug discovery
31. Targeting the ALS/FTD-associated A-DNA kink with anthracene-based metal complex causes DNA backbone straightening and groove contraction
32. The structural basis of actinomycin D–binding induces nucleotide flipping out, a sharp bend and a left-handed twist in CGG triplet repeats
33. Structural Basis for Targeting T:T Mismatch with Triaminotriazine-Acridine Conjugate Induces a U-Shaped Head-to-Head Four-Way Junction in CTG Repeat DNA
34. Structure-Based Stabilization of Non-native Protein–Protein Interactions of Coronavirus Nucleocapsid Proteins in Antiviral Drug Design
35. Elucidation of the stability and functional regions of the human coronavirus OC43 nucleocapsid protein†
36. Mithramycin forms a stable dimeric complex by chelating with Fe(II): DNA-interacting characteristics, cellular permeation and cytotoxicity
37. Crystal structure of the [Mg2+-(chromomycin A3)2]–d(TTGGCCAA)2 complex reveals GGCC binding specificity of the drug dimer chelated by a metal ion
38. Crystal structure of actinomycin D bound to the CTG triplet repeat sequences linked to neurological diseases
39. Effects of polyamines on the thermal stability and formation kinetics of DNA duplexes with abnormal structure
40. Crystal Structure-Based Exploration of Arginine-Containing Peptide Binding in the ADP-Ribosyltransferase Domain of the Type III Effector XopAI Protein
41. Polymorphic G:G mismatches act as hotspots for inducing right-handed Z DNA by DNA intercalation
42. CoII(Chromomycin)2 Complex Induces a Conformational Change of CCG Repeats from i-Motif to Base-Extruded DNA Duplex
43. A survey of recent unusual high-resolution DNA structures provoked by mismatches, repeats and ligand binding
44. Crystallographic analysis of the Staphylococcus epidermidis lipase involved in esterification in aqueous solution
45. Cooperative recognition of T:T mismatch by echinomycin causes structural distortions in DNA duplex
46. Induced-Fit Recognition of CCG Trinucleotide Repeats by a Nickel-Chromomycin Complex Resulting in Large-Scale DNA Deformation
47. Oligomerization of the carboxyl terminal domain of the human coronavirus 229E nucleocapsid protein
48. Selective recognition and stabilization of new ligands targeting the potassium form of the human telomeric G-quadruplex DNA
49. Using mutagenesis to explore conserved residues in the RNA-binding groove of influenza A virus nucleoprotein for antiviral drug development
50. Crystal structure of vespid phospholipase A1 reveals insights into the mechanism for cause of membrane dysfunction
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