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2. General and abdominal adiposity and hypertension in eight world regions: a pooled analysis of 837 population-based studies with 7·5 million participants
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Zhou, Bin, Bennett, James E, Wickham, Aidan P, Singleton, Rosie K, Mishra, Anu, Carrillo-Larco, Rodrigo M, Ikeda, Nayu, Jain, Lakshya, Barradas-Pires, Ana, Heap, Rachel A, Lhoste, Victor PF, Sheffer, Kate E, Phelps, Nowell H, Rayner, Archie W, Gregg, Edward W, Woodward, Mark, Stevens, Gretchen A, Iurilli, Maria LC, Danaei, Goodarz, Di Cesare, Mariachiara, Aguilar-Salinas, Carlos A, Ahmad, Noor Ani, Bovet, Pascal, Chen, Zhengming, Damasceno, Albertino, Filippi, Sarah L, Janszky, Imre, Kengne, Andre P, Khang, Young-Ho, Khunti, Kamlesh, Laxmaiah, Avula, Lim, Lee-Ling, Lissner, Lauren, Margozzini, Paula, Mbanya, Jean Claude N, McGarvey, Stephen T, Shaw, Jonathan E, Söderberg, Stefan, Soto-Mota, Luis Adrián, Wang, Junyang, Zaccardi, Francesco, Abarca-Gómez, Leandra, Abbasi-Kangevari, Mohsen, Abdrakhmanova, Shynar, Abdul Ghaffar, Suhaila, Abdul Rahim, Hanan F, Abdurrahmonova, Zulfiya, Abu-Rmeileh, Niveen M, Acosta-Cazares, Benjamin, Adam, Ishag, Adamczyk, Marzena, Aekplakorn, Wichai, Agdeppa, Imelda A, Aghazadeh-Attari, Javad, Agyemang, Charles, Ahmad, Mohamad Hasnan, Ahmadi, Ali, Ahmadi, Naser, Ahmadi, Nastaran, Ahmed, Soheir H, Ahrens, Wolfgang, Aitmurzaeva, Gulmira, Ajlouni, Kamel, Al-Hazzaa, Hazzaa M, Al-Hinai, Halima, Al-Lawati, Jawad A, Al-Raddadi, Rajaa, Al Asfoor, Deena, Al Hourani, Huda M, Alarouj, Monira, AlBuhairan, Fadia, AlDhukair, Shahla, Ali, Mohamed M, Alieva, Anna V, Alkandari, Abdullah, Alkhatib, Buthaina M, Aly, Eman, Amarapurkar, Deepak N, Amiano Etxezarreta, Pilar, Amougou, Norbert, Andersen, Lars Bo, Anderssen, Sigmund A, Androutsos, Odysseas, Anjana, Ranjit Mohan, Ansari-Moghaddam, Alireza, Anufrieva, Elena, Aounallah-Skhiri, Hajer, Aris, Tahir, Arku, Raphael E, Arlappa, Nimmathota, Aryal, Krishna K, Assah, Felix K, Assembekov, Batyrbek, Assunção, Maria Cecília F, Auvinen, Juha, Avdičová, Mária, Azad, Kishwar, Azevedo, Ana, Azimi-Nezhad, Mohsen, Azizi, Fereidoun, Bacopoulou, Flora, Bahijri, Suhad, Bajramovic, Izet, Balakrishna, Nagalla, 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Francisco J, Ferguson, Trevor S, Fernandes, Romulo A, Fernández-Bergés, Daniel, Fernando, Desha R, Ferrante, Daniel, Ferrari, Gerson, Ferrari, Marika, Ferreccio, Catterina, Ferrer, Eldridge, Figueiró, Thamara Hubler, Fijalkowska, Anna, Fink, Günther, Fisberg, Mauro, Forsner, Maria, Fottrell, Edward F, Fouad, Heba M, Francis, Damian K, Frontera, Guillermo, Fuchs, Flavio D, Fuchs, Sandra C, Furdela, Viktoriya, Furusawa, Takuro, Gabriela, Stefan Adela, Gaciong, Zbigniew, Galán Cuesta, Manuel, Galbarczyk, Andrzej, Galcheva, Sonya V, Galfo, Myriam, Garcia-de-la-Hera, Manoli, Garcia, Pablo, Garnett, Sarah P, Gasull, Magda, Gazzinelli, Andrea, Gehring, Ulrike, Gerdts, Eva, Ghaderi, Ebrahim, Ghamari, Seyyed-Hadi, Ghanbari, Ali, Ghasemi, Erfan, Gheorghe-Fronea, Oana-Florentina, Ghimire, Anup, Gialluisi, Alessandro, Giampaoli, Simona, Gianfagna, Francesco, Gironella, Glen, Giwercman, Aleksander, Gkiouras, Konstantinos, Glushkova, Natalya, Godara, Ramesh, Godos, Justyna, Goldberg, Marcel, Gómez, Georgina, Gómez Gómez, Jesús Humberto, Gomez, Luis F, Gómez, Santiago F, Gomula, Aleksandra, Gonçalves Cordeiro da Silva, Bruna, Gonçalves, Helen, Gonçalves, Mauer, González-Alvarez, Ana D, Gonzalez-Chica, David A, González-Gil, Esther M, Gonzalez-Gross, Marcela, González-Rivas, Juan P, Gonzalez, Angel R, Gottrand, Frederic, Grafnetter, Dušan, Grajda, Aneta, Grammatikopoulou, Maria G, Grodzicki, Tomasz, Grøholt, Else Karin, Grøntved, Anders, Guajardo, Viviana, Guallar-Castillón, Pilar, Guerchet, Maëlenn, Guerrero, Ramiro, Guimaraes, Andre L, Gujral, Unjali P, Gulliford, Martin C, Gunter, Marc J, Gupta, Rajeev, Gureje, Oye, Gurinović, Mirjana A, Gurzkowska, Beata, Gutierrez, Laura, Gwee, Xinyi, Haghshenas, Rosa, Hakimi, Hamid, Halkjær, Jytte, Hambleton, Ian R, Hamzeh, Behrooz, Hanekom, Willem A, Hange, Dominique, Hanif, Abu AM, Hantunen, Sari, Hao, Jie, Hardman, Carla Menêses, Hardy, Louise, Hari Kumar, Rachakulla, Harooni, Javad, Hashemi-Shahri, Seyed Mohammad, Hassapidou, Maria, Hata, 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Tuija, Jackson, Rod T, Jaddou, Hashem Y, Jadoul, Michel, Jafar, Tazeen, Jan, Nataša, Janus, Edward, Jarani, Juel, Jarnig, Gerald, Jarvelin, Marjo-Riitta, Jasienska, Grazyna, Jelaković, Ana, Jelaković, Bojan, Jha, Anjani Kumar, Jimenez, Ramon O, Jöckel, Karl-Heinz, Joffres, Michel, Jokelainen, Jari J, Jonas, Jost B, Joshi, Pradeep, Joshi, Rohina, Josipović, Josipa, Joukar, Farahnaz, Jóźwiak, Jacek J, Juolevi, Anne, Juresa, Vesna, Jureša, Vesna, Kaaks, Rudolf, Kaducu, Felix O, Kadvan, Agnes L, Kafatos, Anthony, Kajantie, Eero O, Kakutia, Natia, Kállayová, Daniela, Kalmatayeva, Zhanna, Kalter-Leibovici, Ofra, Kannan, Srinivasan, Kapantais, Efthymios, Karaglani, Eva, Karakosta, Argyro, Karki, Khem B, Kassi Anicet, Adoubi, Katibeh, Marzieh, Katulanda, Prasad, Katzmarzyk, Peter T, Kauhanen, Jussi, Kazakbaeva, Gyulli M, Kaze, François F, Ke, Calvin, Keinänen-Kiukaanniemi, Sirkka, Kelishadi, Roya, Kelleher, Cecily, Kemper, Han CG, Keramati, Maryam, Kersting, Mathilde, Khader, Yousef Saleh, Khaledifar, Arsalan, Khalili, Davood, Kheiri, Bahareh, Kheradmand, Motahareh, Khosravi, Alireza, Kiechl-Kohlendorfer, Ursula, Kiechl, Sophia J, Kiechl, Stefan, Kim, Hyeon Chang, Klakk, Heidi, Klanarong, Suntara, Klanova, Jana, Klimek, Magdalena, Knoflach, Michael, Kobel, Susanne, Koirala, Bhawesh, Kolle, Elin, Kolsteren, Patrick, König, Jürgen, Korpelainen, Raija, Korrovits, Paul, Korzycka, Magdalena, Kos, Jelena, Koskinen, Seppo, Koussoh Simone, Malik, Kovács, Éva, Kovalskys, Irina, Kowlessur, Sudhir, Koziel, Slawomir, Kratenova, Jana, Kratzer, Wolfgang, Kriemler, Susi, Kristensen, Peter Lund, Krizan, Helena, Kroker-Lobos, Maria F, Krokstad, Steinar, Kruger, Herculina S, Kruger, Ruan, Kryst, Łukasz, Kubinova, Ruzena, Kujala, Urho M, Kujundzic, Enisa, Kulaga, Zbigniew, Kulimbet, Mukhtar, Kumari, Meena, Kunešová, Marie, Kurjata, Pawel, Kyobutungi, Catherine, La, Quang Ngoc, Labadarios, Demetre, Lachat, Carl, Lai, Daphne, Laid, Youcef, Lall, Lachmie, Landaeta Jimenez, Maritza, Landais, 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3. Worldwide trends in underweight and obesity from 1990 to 2022: a pooled analysis of 3663 population-representative studies with 222 million children, adolescents, and adults
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Maciej, Topbas, Murat, Topór-Mądry, Roman, Torheim, Liv Elin, Tornaritis, Michael J, Torrent, Maties, Torres-Collado, Laura, Toselli, Stefania, Touloumi, Giota, Traissac, Pierre, Tran, Thi Tuyet-Hanh, Tremblay, Mark S, Triantafyllou, Areti, Trichopoulos, Dimitrios, Trichopoulou, Antonia, Trinh, Oanh TH, Trivedi, Atul, Tshepo, Lechaba, Tsigga, Maria, Tsintavis, Panagiotis, Tsugane, Shoichiro, Tuitele, John, Tuliakova, Azaliia M, Tulloch-Reid, Marshall K, Tullu, Fikru, Tuomainen, Tomi-Pekka, Tuomilehto, Jaakko, Twig, Gilad, Tynelius, Per, Tzala, Evangelia, Tzotzas, Themistoklis, Tzourio, Christophe, Udoji, Nwannedimma, Ueda, Peter, Ugel, Eunice, Ukoli, Flora AM, Ulmer, Hanno, Unal, Belgin, Usupova, Zhamyila, Uusitalo, Hannu MT, Uysal, Nalan, Vaitkeviciute, Justina, Valdivia, Gonzalo, Vale, Susana, Valvi, Damaskini, van Dam, Rob M, van den Born, Bert-Jan, Van der Heyden, Johan, van der Schouw, Yvonne T, Van Herck, Koen, Van Lippevelde, Wendy, Van Minh, Hoang, Van Schoor, Natasja M, van Valkengoed, Irene GM, Vanderschueren, Dirk, Vanuzzo, Diego, Varbo, Anette, Varela-Moreiras, Gregorio, Vargas, Luz Nayibe, Varona-Pérez, Patricia, Vasan, Senthil K, Vasques, Daniel G, Vatasescu, Radu, Vega, Tomas, Veidebaum, Toomas, Velasquez-Melendez, Gustavo, Velika, Biruta, Verloigne, Maïté, Veronesi, Giovanni, Verschuren, WM Monique, Victora, Cesar G, Viegi, Giovanni, Viet, Lucie, Vik, Frøydis N, Vilar, Monica, Villalpando, Salvador, Vioque, Jesus, Viriyautsahakul, Napaphan, Virtanen, Jyrki K, Visser, Marjolein, Visvikis-Siest, Sophie, Viswanathan, Bharathi, Vladulescu, Mihaela, Vlasoff, Tiina, Vocanec, Dorja, Vollenweider, Peter, Völzke, Henry, Vourli, Georgia, Voutilainen, Ari, Vrijheid, Martine, Vrijkotte, Tanja GM, Vuletić, Silvije, Wade, Alisha N, Waldhör, Thomas, Walton, Janette, Wambiya, Elvis OA, Wan Bebakar, Wan Mohamad, Wan Mohamud, Wan Nazaimoon, Wanderley Júnior, Rildo de Souza, Wang, Chongjian, Wang, Huijun, Wang, Ming-Dong, Wang, Ningli, Wang, Qian, Wang, Xiangjun, Wang, Ya Xing, Wang, Ying-Wei, Wannamethee, S Goya, Wareham, Nicholas, Wartha, Olivia, Weber, Adelheid, Wedderkopp, Niels, Weghuber, Daniel, Wei, Wenbin, Weres, Aneta, Werner, Bo, Westbury, Leo D, Whincup, Peter H, Wichstrøm, Lars, Wickramasinghe, Kremlin, Widhalm, Kurt, Widyahening, Indah S, Więcek, Andrzej, Wild, Philipp S, Wilks, Rainford J, Willeit, Johann, Willeit, Peter, Williams, Julianne, Wilsgaard, Tom, Wirth, James P, Wojtyniak, Bogdan, Woldeyohannes, Meseret, Wolf, Kathrin, Wong-McClure, Roy A, Wong, Andrew, Wong, Emily B, Wong, Jyh Eiin, Wong, Tien Yin, Woo, Jean, Woodward, Mark, Wu, Frederick C, Wu, Hon-Yen, Wu, Jianfeng, Wu, Li Juan, Wu, Shouling, Wyszyńska, Justyna, Xu, Haiquan, Xu, Liang, Yaacob, Nor Azwany, Yamborisut, Uruwan, Yan, Li, Yan, Weili, Yang, Ling, Yang, Xiaoguang, Yang, Yang, Yardim, Nazan, Yasuharu, Tabara, Yépez García, Martha, Yiallouros, Panayiotis K, Yngve, Agneta, Yoosefi, Moein, Yoshihara, Akihiro, Yotov, Yoto, You, Qi Sheng, You, San-Lin, Younger-Coleman, Novie O, Yu, Yu-Ling, Yu, Yunjiang, Yusof, Safiah Md, Yusoff, Ahmad Faudzi, Zaccagni, Luciana, Zafiropulos, Vassilis, Zainuddin, Ahmad A, Zakavi, Seyed Rasoul, Zamani, Farhad, Zambon, Sabina, Zampelas, Antonis, Zamrazilová, Hana, Zapata, Maria Elisa, Zargar, Abdul Hamid, Zaw, Ko Ko, Zayed, Ayman A, Zdrojewski, Tomasz, Żegleń, Magdalena, Zejglicova, Kristyna, Zeljkovic Vrkic, Tajana, Zeng, Yi, Zentai, Andrea, Zhang, Bing, Zhang, Luxia, Zhang, Zhen-Yu, Zhao, Dong, Zhao, Ming-Hui, Zhao, Wenhua, Zhecheva, Yanitsa V, Zhen, Shiqi, Zheng, Wei, Zheng, Yingfeng, Zholdin, Bekbolat, Zhou, Maigeng, Zhu, Dan, Zimmet, Paul, Zins, Marie, Zitt, Emanuel, Zocalo, Yanina, Zoghlami, Nada, Zuñiga Cisneros, Julio, Zuziak, Monika, and Ezzati, Majid
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- 2024
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4. Genome-wide association analyses of physical activity and sedentary behavior provide insights into underlying mechanisms and roles in disease prevention
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Wang, Zhe, Emmerich, Andrew, Pillon, Nicolas J., Moore, Tim, Hemerich, Daiane, Cornelis, Marilyn C., Mazzaferro, Eugenia, Broos, Siacia, Ahluwalia, Tarunveer S., Bartz, Traci M., Bentley, Amy R., Bielak, Lawrence F., Chong, Mike, Chu, Audrey Y., Berry, Diane, Dorajoo, Rajkumar, Dueker, Nicole D., Kasbohm, Elisa, Feenstra, Bjarke, Feitosa, Mary F., Gieger, Christian, Graff, Mariaelisa, Hall, Leanne M., Haller, Toomas, Hartwig, Fernando P., Hillis, David A., Huikari, Ville, Heard-Costa, Nancy, Holzapfel, Christina, Jackson, Anne U., Johansson, Åsa, Jørgensen, Anja Moltke, Kaakinen, Marika A., Karlsson, Robert, Kerr, Kathleen F., Kim, Boram, Koolhaas, Chantal M., Kutalik, Zoltan, Lagou, Vasiliki, Lind, Penelope A., Lorentzon, Mattias, Lyytikäinen, Leo-Pekka, Mangino, Massimo, Metzendorf, Christoph, Monroe, Kristine R., Pacolet, Alexander, Pérusse, Louis, Pool, Rene, Richmond, Rebecca C., Rivera, Natalia V., Robiou-du-Pont, Sebastien, Schraut, Katharina E., Schulz, Christina-Alexandra, Stringham, Heather M., Tanaka, Toshiko, Teumer, Alexander, Turman, Constance, van der Most, Peter J., Vanmunster, Mathias, van Rooij, Frank J. A., van Vliet-Ostaptchouk, Jana V., Zhang, Xiaoshuai, Zhao, Jing-Hua, Zhao, Wei, Balkhiyarova, Zhanna, Balslev-Harder, Marie N., Baumeister, Sebastian E., Beilby, John, Blangero, John, Boomsma, Dorret I., Brage, Soren, Braund, Peter S., Brody, Jennifer A., Bruinenberg, Marcel, Ekelund, Ulf, Liu, Ching-Ti, Cole, John W., Collins, Francis S., Cupples, L. Adrienne, Esko, Tõnu, Enroth, Stefan, Faul, Jessica D., Fernandez-Rhodes, Lindsay, Fohner, Alison E., Franco, Oscar H., Galesloot, Tessel E., Gordon, Scott D., Grarup, Niels, Hartman, Catharina A., Heiss, Gerardo, Hui, Jennie, Illig, Thomas, Jago, Russell, James, Alan, Joshi, Peter K., Jung, Taeyeong, Kähönen, Mika, Kilpeläinen, Tuomas O., Koh, Woon-Puay, Kolcic, Ivana, Kraft, Peter P., Kuusisto, Johanna, Launer, Lenore J., Li, Aihua, Linneberg, Allan, Luan, Jian’an, Vidal, Pedro Marques, Medland, Sarah E., Milaneschi, Yuri, Moscati, Arden, Musk, Bill, Nelson, Christopher P., Nolte, Ilja M., Pedersen, Nancy L., Peters, Annette, Peyser, Patricia A., Power, Christine, Raitakari, Olli T., Reedik, Mägi, Reiner, Alex P., Ridker, Paul M., Rudan, Igor, Ryan, Kathy, Sarzynski, Mark A., Scott, Laura J., Scott, Robert A., Sidney, Stephen, Siggeirsdottir, Kristin, Smith, Albert V., Smith, Jennifer A., Sonestedt, Emily, Strøm, Marin, Tai, E. Shyong, Teo, Koon K., Thorand, Barbara, Tönjes, Anke, Tremblay, Angelo, Uitterlinden, Andre G., Vangipurapu, Jagadish, van Schoor, Natasja, Völker, Uwe, Willemsen, Gonneke, Williams, Kayleen, Wong, Quenna, Xu, Huichun, Young, Kristin L., Yuan, Jian Min, Zillikens, M. Carola, Zonderman, Alan B., Ameur, Adam, Bandinelli, Stefania, Bis, Joshua C., Boehnke, Michael, Bouchard, Claude, Chasman, Daniel I., Smith, George Davey, de Geus, Eco J. C., Deldicque, Louise, Dörr, Marcus, Evans, Michele K., Ferrucci, Luigi, Fornage, Myriam, Fox, Caroline, Garland, Jr, Theodore, Gudnason, Vilmundur, Gyllensten, Ulf, Hansen, Torben, Hayward, Caroline, Horta, Bernardo L., Hyppönen, Elina, Jarvelin, Marjo-Riitta, Johnson, W. Craig, Kardia, Sharon L. R., Kiemeney, Lambertus A., Laakso, Markku, Langenberg, Claudia, Lehtimäki, Terho, Marchand, Loic Le, Magnusson, Patrik K. E., Martin, Nicholas G., Melbye, Mads, Metspalu, Andres, Meyre, David, North, Kari E., Ohlsson, Claes, Oldehinkel, Albertine J., Orho-Melander, Marju, Pare, Guillaume, Park, Taesung, Pedersen, Oluf, Penninx, Brenda W. J. H., Pers, Tune H., Polasek, Ozren, Prokopenko, Inga, Rotimi, Charles N., Samani, Nilesh J., Sim, Xueling, Snieder, Harold, Sørensen, Thorkild I. A., Spector, Tim D., Timpson, Nicholas J., van Dam, Rob M., van der Velde, Nathalie, van Duijn, Cornelia M., Vollenweider, Peter, Völzke, Henry, Voortman, Trudy, Waeber, Gérard, Wareham, Nicholas J., Weir, David R., Wichmann, Heinz-Erich, Wilson, James F., Hevener, Andrea L., Krook, Anna, Zierath, Juleen R., Thomis, Martine A. I., Loos, Ruth J. F., and Hoed, Marcel den
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- 2022
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5. Early-life stature, preschool cognitive development, schooling attainment, and cognitive functioning in adulthood: a prospective study in four birth cohorts
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Kowalski, Alysse, DiGirolamo, Ann, Scerif, Gaia, Mpondo, Feziwe, Belleza, Delia, Nyati, Lukhanyo, Osmond, Clive, Borja, Judith Rafaelita, Carba, Delia, Perez, Tita Lorna, Bechavda, Sonny Agustin, Kroker-Lobos, Maria F, Varghese, Jithin S, Barros, Fernando C, Hartwig, Fernando P, Horta, Bernardo L, Wehrmeister, Fernando C, Stein, Aryeh D, Adair, Linda S, Donati, Georgina, Wray, Charlotte, Richter, Linda M, Norris, Shane A, Stein, Alan, Martorell, Reynaldo, Ramirez-Zea, Manuel, Menezes, Ana M B, Murray, Joseph, Victora, Cesar, Lee, Nanette, and Bas, Isabelita
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- 2023
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6. Author Correction: Whole-genome sequencing of 1,171 elderly admixed individuals from Brazil
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Naslavsky, Michel S., Scliar, Marilia O., Yamamoto, Guilherme L., Wang, Jaqueline Yu Ting, Zverinova, Stepanka, Karp, Tatiana, Nunes, Kelly, Ceroni, José Ricardo Magliocco, de Carvalho, Diego Lima, da Silva Simões, Carlos Eduardo, Bozoklian, Daniel, Nonaka, Ricardo, dos Santos Brito Silva, Nayane, da Silva Souza, Andreia, de Souza Andrade, Heloísa, Passos, Marília Rodrigues Silva, Castro, Camila Ferreira Bannwart, Mendes-Junior, Celso T., Mercuri, Rafael L. V., Miller, Thiago L. A., Buzzo, Jose Leonel, Rego, Fernanda O., Araújo, Nathalia M., Magalhães, Wagner C. S., Mingroni-Netto, Regina Célia, Borda, Victor, Guio, Heinner, Rojas, Carlos P., Sanchez, Cesar, Caceres, Omar, Dean, Michael, Barreto, Mauricio L., Lima-Costa, Maria Fernanda, Horta, Bernardo L., Tarazona-Santos, Eduardo, Meyer, Diogo, Galante, Pedro A. F., Guryev, Victor, Castelli, Erick C., Duarte, Yeda A. O., Passos-Bueno, Maria Rita, and Zatz, Mayana
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- 2022
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7. Whole-genome sequencing of 1,171 elderly admixed individuals from Brazil
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Naslavsky, Michel S., Scliar, Marilia O., Yamamoto, Guilherme L., Wang, Jaqueline Yu Ting, Zverinova, Stepanka, Karp, Tatiana, Nunes, Kelly, Ceroni, José Ricardo Magliocco, de Carvalho, Diego Lima, da Silva Simões, Carlos Eduardo, Bozoklian, Daniel, Nonaka, Ricardo, dos Santos Brito Silva, Nayane, da Silva Souza, Andreia, de Souza Andrade, Heloísa, Passos, Marília Rodrigues Silva, Castro, Camila Ferreira Bannwart, Mendes-Junior, Celso T., Mercuri, Rafael L. V., Miller, Thiago L. A., Buzzo, Jose Leonel, Rego, Fernanda O., Araújo, Nathalia M., Magalhães, Wagner C. S., Mingroni-Netto, Regina Célia, Borda, Victor, Guio, Heinner, Rojas, Carlos P., Sanchez, Cesar, Caceres, Omar, Dean, Michael, Barreto, Mauricio L., Lima-Costa, Maria Fernanda, Horta, Bernardo L., Tarazona-Santos, Eduardo, Meyer, Diogo, Galante, Pedro A. F., Guryev, Victor, Castelli, Erick C., Duarte, Yeda A. O., Passos-Bueno, Maria Rita, and Zatz, Mayana
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- 2022
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8. Effects of early-life poverty on health and human capital in children and adolescents: analyses of national surveys and birth cohort studies in LMICs
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Victora, Cesar G, Hartwig, Fernando P, Vidaletti, Luis P, Martorell, Reynaldo, Osmond, Clive, Richter, Linda M, Stein, Aryeh D, Barros, Aluisio J D, Adair, Linda S, Barros, Fernando C, Bhargava, Santosh K, Horta, Bernardo L, Kroker-Lobos, Maria F, Lee, Nanette R, Menezes, Ana Maria B, Murray, Joseph, Norris, Shane A, Sachdev, Harshpal S, Stein, Alan, Varghese, Jithin S, Bhutta, Zulfiqar A, and Black, Robert E
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- 2022
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9. Economic costs of childhood stunting to the private sector in low- and middle-income countries
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Akseer, Nadia, Tasic, Hana, Nnachebe Onah, Michael, Wigle, Jannah, Rajakumar, Ramraj, Sanchez-Hernandez, Diana, Akuoku, Jonathan, Black, Robert E, Horta, Bernardo L, Nwuneli, Ndidi, Shine, Ritta, Wazny, Kerri, Japra, Nikita, Shekar, Meera, and Hoddinott, John
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- 2022
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10. Maternal smoking during pregnancy and intelligence quotient of offspring aged 18 and 30 years: Evidence from two birth cohorts in southern Brazil
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Corrêa, Mariana Lima, da Silva, Bruna Gonçalves Cordeiro, Wehrmeister, Fernando C., Horta, Bernardo L., Gonçalves, Helen, Anselmi, Luciana, Barros, Fernando, and Menezes, Ana Maria Baptista
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- 2022
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11. Differential effect of social mobility on tooth loss by race in adulthood: 1982 Pelotas Birth Cohort Study.
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Karam, Sarah Arangurem, Schuch, Helena Silveira, Demarco, Flávio Fernando, Horta, Bernardo L., Borrell, Luisa N., Celeste, Roger Keller, and Correa, Marcos Britto
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RESEARCH funding ,SOCIOECONOMIC factors ,SOCIAL mobility ,DESCRIPTIVE statistics ,RACE ,LONGITUDINAL method ,DENTAL caries ,COMPARATIVE studies ,CONFIDENCE intervals ,TOOTH loss ,DISEASE complications ,ADULTS - Abstract
Objectives: To examine the association between social mobility and tooth loss in adults from the 1982 Pelotas Birth Cohort Study and whether race modifies this association. Methods: The Oral Health Study used data from 541 individuals who were followed up to 31 years of age. Social mobility, composed of the participants' socioeconomic position (SEP) at birth and at age 30, was categorized as never poor, upwardly mobile, downwardly mobile and always poor. The outcome was the prevalence of at least one tooth lost due to dental caries when the participants were examined at 31 years of age. The effect modifier was race (Black/Brown versus white people). Log‐binomial regression models were used to estimate crude and sex‐adjusted prevalence ratios (PR) and to determine whether the association varied with race. Statistical interactions were tested using an additive scale. Results: The prevalence of any tooth loss was 50.8% (n = 274). In social mobility groups, the prevalence of at least one tooth lost in the never‐poor group was about 31% points higher for Black/Brown (68.2%) than for white people (37.4%). Antagonistic findings were found for the interaction between race and social mobility (Sinergy Index = 0.48; 95% CI 0.24, 0.99; and relative excess of risk due to the interaction = −1.38; 95% CI −2.34, −0.42), suggesting that the observed joint effect of race and social mobility on tooth loss was lower than the expected sum of these factors. The estimates for Black/Brown people were smaller for those who were always poor during their lives, relative to their white counterparts. Conclusions: The findings suggest a higher prevalence of at least one tooth lost among people in the downward mobile SEP group and Black/Brown people. Greater racial inequity was found among Black/Brown people who had never experienced episodes of poverty, with Black/Brown people having a greater prevalence of at least one tooth lost than their white counterparts. [ABSTRACT FROM AUTHOR]
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- 2024
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12. Life-Course Genome-wide Association Study Meta-analysis of Total Body BMD and Assessment of Age-Specific Effects
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Medina-Gomez, Carolina, Kemp, John P, Trajanoska, Katerina, Luan, Jian’an, Chesi, Alessandra, Ahluwalia, Tarunveer S, Mook-Kanamori, Dennis O, Ham, Annelies, Hartwig, Fernando P, Evans, Daniel S, Joro, Raimo, Nedeljkovic, Ivana, Zheng, Hou-Feng, Zhu, Kun, Atalay, Mustafa, Liu, Ching-Ti, Nethander, Maria, Broer, Linda, Porleifsson, Gudmar, Mullin, Benjamin H, Handelman, Samuel K, Nalls, Mike A, Jessen, Leon E, Heppe, Denise HM, Richards, J Brent, Wang, Carol, Chawes, Bo, Schraut, Katharina E, Amin, Najaf, Wareham, Nick, Karasik, David, Van der Velde, Nathalie, Ikram, M Arfan, Zemel, Babette S, Zhou, Yanhua, Carlsson, Christian J, Liu, Yongmei, McGuigan, Fiona E, Boer, Cindy G, Bønnelykke, Klaus, Ralston, Stuart H, Robbins, John A, Walsh, John P, Zillikens, M Carola, Langenberg, Claudia, Li-Gao, Ruifang, Williams, Frances MK, Harris, Tamara B, Akesson, Kristina, Jackson, Rebecca D, Sigurdsson, Gunnar, Heijer, Martin den, van der Eerden, Bram CJ, van de Peppel, Jeroen, Spector, Timothy D, Pennell, Craig, Horta, Bernardo L, Felix, Janine F, Zhao, Jing Hua, Wilson, Scott G, de Mutsert, Renée, Bisgaard, Hans, Styrkársdóttir, Unnur, Jaddoe, Vincent W, Orwoll, Eric, Lakka, Timo A, Scott, Robert, Grant, Struan FA, Lorentzon, Mattias, van Duijn, Cornelia M, Wilson, James F, Stefansson, Kari, Psaty, Bruce M, Kiel, Douglas P, Ohlsson, Claes, Ntzani, Evangelia, van Wijnen, Andre J, Forgetta, Vincenzo, Ghanbari, Mohsen, Logan, John G, Williams, Graham R, Bassett, JH Duncan, Croucher, Peter I, Evangelou, Evangelos, Uitterlinden, Andre G, Ackert-Bicknell, Cheryl L, Tobias, Jonathan H, Evans, David M, and Rivadeneira, Fernando
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Rare Diseases ,Aging ,Human Genome ,Osteoporosis ,Clinical Research ,Genetics ,Aetiology ,2.1 Biological and endogenous factors ,Musculoskeletal ,Good Health and Well Being ,Adolescent ,Age Factors ,Animals ,Bone Density ,Child ,Child ,Preschool ,Genetic Loci ,Genome-Wide Association Study ,Humans ,Infant ,Infant ,Newborn ,Mice ,Knockout ,Polymorphism ,Single Nucleotide ,Quantitative Trait ,Heritable ,Regression Analysis ,BMD ,CREB3L1 ,ESR1 ,GWASs ,RANKL ,age-dependent effects ,bone mineral density ,fracture ,genetic correlation ,genome-wide association studies ,meta-regression ,total-body DXA ,Biological Sciences ,Medical and Health Sciences ,Genetics & Heredity - Abstract
Bone mineral density (BMD) assessed by DXA is used to evaluate bone health. In children, total body (TB) measurements are commonly used; in older individuals, BMD at the lumbar spine (LS) and femoral neck (FN) is used to diagnose osteoporosis. To date, genetic variants in more than 60 loci have been identified as associated with BMD. To investigate the genetic determinants of TB-BMD variation along the life course and test for age-specific effects, we performed a meta-analysis of 30 genome-wide association studies (GWASs) of TB-BMD including 66,628 individuals overall and divided across five age strata, each spanning 15 years. We identified variants associated with TB-BMD at 80 loci, of which 36 have not been previously identified; overall, they explain approximately 10% of the TB-BMD variance when combining all age groups and influence the risk of fracture. Pathway and enrichment analysis of the association signals showed clustering within gene sets implicated in the regulation of cell growth and SMAD proteins, overexpressed in the musculoskeletal system, and enriched in enhancer and promoter regions. These findings reveal TB-BMD as a relevant trait for genetic studies of osteoporosis, enabling the identification of variants and pathways influencing different bone compartments. Only variants in ESR1 and close proximity to RANKL showed a clear effect dependency on age. This most likely indicates that the majority of genetic variants identified influence BMD early in life and that their effect can be captured throughout the life course.
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- 2018
13. Changes in asset-based wealth across the life course in birth cohorts from five low- and middle-income countries
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Varghese, Jithin Sam, Adair, Linda S., Patel, Shivani A., Bechayda, Sonny Agustin, Bhargava, Santosh K., Carba, Delia B., Horta, Bernardo L., Lima, Natalia P., Martorell, Reynaldo, Menezes, Ana M.B., Norris, Shane A., Richter, Linda M., Ramirez-Zea, Manuel, Sachdev, Harshpal Singh, Wehrmeister, Fernando C., and Stein, Aryeh D.
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- 2021
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14. Comparing the effect of imputation reference panel composition in four distinct Latin American cohorts
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French, Jennifer N, primary, Borda Pua, Victor Octavio, additional, Laboulaye, Roland, additional, Peixoto Leal, Thiago, additional, Cornejo-Olivas, Mario, additional, Lima-Costa, Maria Fernanda, additional, Horta, Bernardo L., additional, Barreto, Mauricio L, additional, Tarazona-Santos, Eduardo, additional, Mata, Ignacio, additional, and O'Connor, Timothy D., additional
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- 2024
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15. Breastfeeding moderates the association of maternal pre-pregnancy nutritional status with offspring body composition at 30 years
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Horta, Bernardo L., primary, Coca, Kelly P., additional, Desai, Mina, additional, Dias, Mariane S., additional, B. Jaccottet, Manoella, additional, and Ross, Michael G., additional
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- 2024
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16. Role of occlusal factors on probable bruxism and orofacial pain: Data from the 1982 Pelotas birth cohort study
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Boscato, Noéli, Nascimento, Gustavo G., Leite, Fabio R.M., Horta, Bernardo L., Svensson, Peter, and Demarco, Flavio F.
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- 2021
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17. Worldwide trends in hypertension prevalence and progress in treatment and control from 1990 to 2019: a pooled analysis of 1201 population-representative studies with 104 million participants
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Zhou, Bin, Carrillo-Larco, Rodrigo M, Danaei, Goodarz, Riley, Leanne M, Paciorek, Christopher J, Stevens, Gretchen A, Gregg, Edward W, Bennett, James E, Solomon, Bethlehem, Singleton, Rosie K, Sophiea, Marisa K, Iurilli, Maria LC, Lhoste, Victor PF, Cowan, Melanie J, Savin, Stefan, Woodward, Mark, Balanova, Yulia, Cifkova, Renata, Damasceno, Albertino, Elliott, Paul, Farzadfar, Farshad, He, Jiang, Ikeda, Nayu, Kengne, Andre P, Khang, Young-Ho, Kim, Hyeon Chang, Laxmaiah, Avula, Lin, Hsien-Ho, Margozzini Maira, Paula, Miranda, J Jaime, Neuhauser, Hannelore, Sundström, Johan, Varghese, Cherian, Widyahening, Indah S, Zdrojewski, Tomasz, Abarca-Gómez, Leandra, Abdeen, Ziad A, Abdul Rahim, Hanan F, Abu-Rmeileh, Niveen M, Acosta-Cazares, Benjamin, Adams, Robert J, Aekplakorn, Wichai, Afsana, Kaosar, Afzal, Shoaib, Agdeppa, Imelda A, Aghazadeh-Attari, Javad, Aguilar-Salinas, Carlos A, Agyemang, Charles, Ahmad, Noor Ani, Ahmadi, Ali, Ahmadi, Naser, Ahmadi, Nastaran, Ahmadizar, Fariba, Ahmed, Soheir H, Ahrens, Wolfgang, Ajlouni, Kamel, Al-Raddadi, Rajaa, Alarouj, Monira, AlBuhairan, Fadia, AlDhukair, Shahla, Ali, Mohamed M, Alkandari, Abdullah, Alkerwi, Ala'a, Allin, Kristine, Aly, Eman, Amarapurkar, Deepak N, Amougou, Norbert, Amouyel, Philippe, Andersen, Lars Bo, Anderssen, Sigmund A, Anjana, Ranjit Mohan, Ansari-Moghaddam, Alireza, Ansong, Daniel, Aounallah-Skhiri, Hajer, Araújo, Joana, Ariansen, Inger, Aris, Tahir, Arku, Raphael E, Arlappa, Nimmathota, Aryal, Krishna K, Aspelund, Thor, Assah, Felix K, Assunção, Maria Cecília F, Auvinen, Juha, Avdićová, Mária, Azevedo, Ana, Azimi-Nezhad, Mohsen, Azizi, Fereidoun, Azmin, Mehrdad, Babu, Bontha V, Bahijri, Suhad, Balakrishna, Nagalla, Bamoshmoosh, Mohamed, Banach, Maciej, Banadinović, Maja, Bandosz, Piotr, Banegas, José R, Baran, Joanna, Barbagallo, Carlo M, Barceló, Alberto, Barkat, Amina, Barreto, Marta, Barros, Aluisio JD, Barros, Mauro Virgílio Gomes, Bartosiewicz, Anna, Basit, Abdul, Bastos, Joao Luiz D, Bata, Iqbal, 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Charles, Soumaré, Aïcha, Sparboe-Nilsen, Bente, Sparrenberger, Karen, Staessen, Jan A, Starc, Gregor, Stavreski, Bill, Steene-Johannessen, Jostein, Stehle, Peter, Stein, Aryeh D, Stergiou, George S, Stessman, Jochanan, Stieber, Jutta, Stöckl, Doris, Stocks, Tanja, Stokwiszewski, Jakub, Stronks, Karien, Strufaldi, Maria Wany, Suka, Machi, Sun, Chien-An, Sung, Yn-Tz, Suriyawongpaisal, Paibul, Sy, Rody G, Syddall, Holly E, Sylva, René Charles, Szklo, Moyses, Tai, E Shyong, Tammesoo, Mari-Liis, Tamosiunas, Abdonas, Tan, Eng Joo, Tang, Xun, Tanser, Frank, Tao, Yong, Tarawneh, Mohammed Rasoul, Tarqui-Mamani, Carolina B, Taylor, Anne, Taylor, Julie, Tebar, William R, Tell, Grethe S, Tello, Tania, Tham, Yih Chung, Thankappan, KR, Theobald, Holger, Theodoridis, Xenophon, Thijs, Lutgarde, Thinggaard, Mikael, Thomas, Nihal, Thorand, Barbara, Thuesen, Betina H, Timmermans, Erik J, Tjandrarini, Dwi H, Tjonneland, Anne, Toft, Ulla, Tolonen, Hanna K, Tolstrup, Janne S, Topbas, Murat, Topór-Madry, Roman, Tormo, María José, Tornaritis, Michael J, Torrent, Maties, Torres-Collado, Laura, Touloumi, Giota, Traissac, Pierre, Triantafyllou, Areti, Trichopoulos, Dimitrios, Trichopoulou, Antonia, Trinh, Oanh TH, Trivedi, Atul, Tshepo, Lechaba, Tsugane, Shoichiro, Tuliakova, Azaliia M, Tulloch-Reid, Marshall K, Tullu, Fikru, Tuomainen, Tomi-Pekka, Tuomilehto, Jaakko, Turley, Maria L, Twig, Gilad, Tynelius, Per, Tzourio, Christophe, Ueda, Peter, Ugel, Eunice, Ulmer, Hanno, Uusitalo, Hannu MT, Valdivia, Gonzalo, Valvi, Damaskini, van Dam, Rob M, van den Born, Bert-Jan, Van der Heyden, Johan, van der Schouw, Yvonne T, Van Herck, Koen, Van Minh, Hoang, Van Schoor, Natasja M, van Valkengoed, Irene GM, van Zutphen, Elisabeth M, Vanderschueren, Dirk, Vanuzzo, Diego, Varbo, Anette, Vasan, Senthil K, Vega, Tomas, Veidebaum, Toomas, Velasquez-Melendez, Gustavo, Veronesi, Giovanni, Verschuren, WM Monique, Verstraeten, Roosmarijn, Victora, Cesar G, Viet, Lucie, Villalpando, Salvador, Vineis, Paolo, Vioque, Jesus, Virtanen, Jyrki K, Visvikis-Siest, Sophie, Viswanathan, Bharathi, Vlasoff, Tiina, Vollenweider, Peter, Voutilainen, Ari, Wade, Alisha N, Walton, Janette, Wambiya, Elvis OA, Wan Bebakar, Wan Mohamad, Wan Mohamud, Wan Nazaimoon, Wanderley Júnior, Rildo de Souza, Wang, Ming-Dong, Wang, Ningli, Wang, Qian, Wang, Xiangjun, Wang, Ya Xing, Wang, Ying-Wei, Wannamethee, S Goya, Wareham, Nicholas, Wei, Wenbin, Weres, Aneta, Werner, Bo, Whincup, Peter H, Widhalm, Kurt, Wiecek, Andrzej, Wilks, Rainford J, Willeit, Johann, Willeit, Peter, Williams, Emmanuel A, Wilsgaard, Tom, Wojtyniak, Bogdan, Wong-McClure, Roy A, Wong, Andrew, Wong, Tien Yin, Woo, Jean, Wu, Frederick C, Wu, Shouling, Wyszynska, Justyna, Xu, Haiquan, Xu, Liang, Yaacob, Nor Azwany, Yan, Weili, Yang, Ling, Yang, Xiaoguang, Yang, Yang, Yasuharu, Tabara, Ye, Xingwang, Yiallouros, Panayiotis K, Yoosefi, Moein, Yoshihara, Akihiro, You, San-Lin, Younger-Coleman, Novie O, Yusoff, Ahmad Faudzi, Zainuddin, Ahmad A, Zakavi, Seyed Rasoul, Zamani, Farhad, Zambon, Sabina, Zampelas, Antonis, Zapata, Maria Elisa, Zaw, Ko Ko, Zejglicova, Kristyna, Zeljkovic Vrkic, Tajana, Zeng, Yi, Zhang, Luxia, Zhang, Zhen-Yu, Zhao, Dong, Zhao, Ming-Hui, Zhen, Shiqi, Zheng, Yingfeng, Zholdin, Bekbolat, Zhu, Dan, Zins, Marie, Zitt, Emanuel, Zocalo, Yanina, Zoghlami, Nada, Zuñiga Cisneros, Julio, and Ezzati, Majid
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- 2021
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18. Time-dependent decay of detectable antibodies against SARS-CoV-2: A comparison of ELISA with two batches of a lateral-flow test
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Silveira, Mariangela F, Mesenburg, Marilia A, Dellagostin, Odir A, de Oliveira, Natasha R, Maia, Mara AC, Santos, Francisco D, Vale, André, Menezes, Ana M B, Victora, Gabriel D, Victora, Cesar G, Barros, Aluisio JD, Vidaletti, Luis Paulo, Hartwig, Fernando P, Barros, Fernando C, Hallal, Pedro C, and Horta, Bernardo L
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- 2021
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19. Social Distancing, Mask Use, and Transmission of Severe Acute Respiratory Syndrome Coronavirus 2, Brazil, April-June 2020
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Goncalves, Marcelo Rodrigues, Reis, Rodrigo Citton Padilha dos, Tolio, Rodrigo Pedroso, Pellanda, Lucia Campos, Schmidt, Maria Ines, Katz, Natan, Mengue, Sotero Serrate, Hallal, Pedro C., Horta, Bernardo L., Silveira, Mariangela Freitas, Umpierre, Roberto Nunes, Bastos-Molina, Cynthia Goulart, da Silva, Rodolfo Souza, and Duncan, Bruce B.
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Epidemics -- Statistics -- Control -- Brazil ,Health - Abstract
We assessed the associations of social distancing and mask use with symptomatic, laboratory-confirmed severe acute respiratory syndrome coronavirus 2 infection in Porto Alegre, Brazil. We conducted a population-based case-control study [...]
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- 2021
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20. Obesity and ADHD: Exploring the role of body composition, BMI polygenic risk score, and reward system genes
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Martins-Silva, Thais, Vaz, Juliana dos Santos, Genro, Júlia Pasqualini, Hutz, Mara Helena, Loret de Mola, Christian, Mota, Nina Roth, Oliveira, Isabel, Gigante, Denise Petrucci, Pinheiro, Ricardo Tavares, Vitola, Eduardo, Grevet, Eugenio, Horta, Bernardo L., Rohde, Luis Augusto, and Tovo-Rodrigues, Luciana
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- 2021
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21. Admixture/fine-mapping in Brazilians reveals a West African associated potential regulatory variant (rs114066381) with a strong female-specific effect on body mass and fat mass indexes
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Scliar, Marilia O., Sant’Anna, Hanaisa P., Santolalla, Meddly L., Leal, Thiago P., Araújo, Nathalia M., Alvim, Isabela, Borda, Victor, Magalhães, Wagner C. S., Gouveia, Mateus H., Lyra, Ricardo, Machado, Moara, Michelin, Lucas, Rodrigues, Maíra R., Araújo, Gilderlanio S., Kehdy, Fernanda S. G., Zolini, Camila, Peixoto, Sérgio V., Luizon, Marcelo R., Lobo, Francisco, Naslavsky, Michel S., Yamamoto, Guilherme L., Duarte, Yeda A. O., Hansen, Matthew E. B., Norris, Shane A., Gilman, Robert H., Guio, Heinner, Hsing, Ann W., Mbulaiteye, Sam M., Mensah, James, Dutil, Julie, Yeager, Meredith, Yeboah, Edward, Tishkoff, Sarah A., Choudhury, Ananyo, Ramsay, Michele, Passos-Bueno, Maria Rita, Zatz, Mayana, O´Connor, Timothy D., Pereira, Alexandre C., Barreto, Mauricio L., Lima-Costa, Maria Fernanda, Horta, Bernardo L., and Tarazona-Santos, Eduardo
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- 2021
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22. Life-course influences of poverty on violence and homicide: 30-year Brazilian birth cohort study.
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Murray, Joseph, Esposti, Michelle Degli, Mola, Christian Loret de, Martins, Rafaela, Smith, Andrew D A C, Moffitt, Terrie E, Heron, Jon, Miranda, Vanessa Iribarrem, Lima, Natalia, and Horta, Bernardo L
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POOR children ,YOUNG adults ,LIFE course approach ,DRUG traffic ,CRIMINAL records - Abstract
Background Homicide is the leading cause of death among young people in Latin America, one of the world's most violent regions. Poverty is widely considered a key cause of violence, but theories suggest different effects of poverty, depending on when it is experienced in the life-course. Longitudinal studies of violence are scarce in Latin America, and very few prospective data are available worldwide to test different life-course influences on homicide. Methods In a prospective birth cohort study following 5914 children born in southern Brazil, we examined the role of poverty at birth, in early childhood, and in early adulthood on violence and homicide perpetration, in criminal records up to age 30 years. A novel Structured Life Course Modelling Approach was used to test competing life-course hypotheses about 'sensitive periods', 'accumulation of risk', and 'downward mobility' regarding the influence of poverty on violence and homicide. Results Cumulative poverty and poverty in early adulthood were the most important influences on violence and homicide perpetration. This supports the hypothesis that early adulthood is a sensitive period for the influence of poverty on lethal and non-lethal violence. Results were replicable using different definitions of poverty and an alternative outcome of self-reported fights. Conclusion Cumulative poverty from childhood to adulthood was an important driver of violence and homicide in this population. However, poverty experienced in early adulthood was especially influential, suggesting the importance of proximal mechanisms for violence in this context, such as unemployment, organized crime, drug trafficking, and ineffective policing and justice systems. [ABSTRACT FROM AUTHOR]
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- 2024
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23. SARS-CoV-2 antibody prevalence in Brazil: results from two successive nationwide serological household surveys
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Hallal, Pedro C, Hartwig, Fernando P, Horta, Bernardo L, Silveira, Mariângela F, Struchiner, Claudio J, Vidaletti, Luís P, Neumann, Nelson A, Pellanda, Lucia C, Dellagostin, Odir A, Burattini, Marcelo N, Victora, Gabriel D, Menezes, Ana M B, Barros, Fernando C, Barros, Aluísio J D, and Victora, Cesar G
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- 2020
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24. Trends in cardiometabolic risk factors in the Americas between 1980 and 2014: a pooled analysis of population-based surveys
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Miranda, J Jaime, Carrillo-Larco, Rodrigo M, Ferreccio, Catterina, Hambleton, Ian R, Lotufo, Paulo A, Nieto-MartSínez, Ramfis, Zhou, Bin, Bentham, James, Bixby, Honor, Hajifathalian, Kaveh, Lu, Yuan, Taddei, Cristina, Abarca-Gómez, Leandra, Acosta-Cazares, Benjamin, Aguilar-Salinas, Carlos A, Andrade, Dolores S, Assunção, Maria Cecília F, Barceló, Alberto, Barros, Aluisio JD, Barros, Mauro VG, Bastos, Joao Luiz D, Bata, Iqbal, Batista, Rosangela L, Benet, Mikhail, Bernabe-Ortiz, Antonio, Bettiol, Heloísa, Bia, Daniel, Bloch, Katia V, Boggia, Jose G, Boissonnet, Carlos P, Brajkovich, Imperia, Brewster, Lizzy M, Cameron, Christine, Cândido, Ana Paula C, Cañete, Felicia, Cardoso, Viviane C, Carmuega, Esteban, Cesar, Juraci A, Chan, Queenie, Christofaro, Diego G, Clarke, Janine, Confortin, Susana C, Craig, Cora L, Cureau, Felipe V, Dias-da-Costa, Juvenal Soares, Diaz, Alejandro, Donoso, Silvana C, d'Orsi, Eleonora, Duarte de Oliveira, Paula, Dumith, Samuel C, Eldemire-Shearer, Denise, Elliott, Paul, Escobedo-de la Peña, Jorge, Ferguson, Trevor S, Fernandes, Romulo A, Ferrante, Daniel, Francis, Damian K, Fuchs, Flavio D, Fuchs, Sandra C, Gazzinelli, Andrea, Goltzman, David, Gonçalves, Helen, Goncalves Cordeiro da Silva, Bruna, Gonzalez, Angel R, Gonzalez-Chica, David A, González-Leon, Margot, González-Rivas, Juan P, González-Villalpando, Clicerio, González-Villalpando, María-Elena, Gorbea Bonet, Mariano, Gregor, Ronald D, Guerrero, Ramiro, Guimaraes, Andre L, Gulliford, Martin C, Gutierrez, Laura, Hernandez Cadena, Leticia, Herrera, Victor M, Hopman, Wilma M, Horimoto, Andrea RVR, Hormiga, Claudia M, Horta, Bernardo L, Howitt, Christina, Irazola, Vilma E, James, Kenneth, Jimenez, Ramon O, Jiménez-Acosta, Santa Magaly, Joffres, Michel, Kolsteren, Patrick, Landrove, Orlando, Lazo-Porras, Maria, Lilly, Christa L, Lima-Costa, M Fernanada, Lopez, Tania, Machado-Coelho, George LL, Machado-Rodrigues, Aristides M, Makdisse, Marcia, Margozzini, Paula, Marques, Larissa Pruner, Martorell, Reynaldo, Mascarenhas, Luis, Matijasevich, Alicia, Mc Donald Posso, Anselmo J, McFarlane, Shelly R, McLean, Scott B, Menezes, Ana Maria B, Miquel, Juan Francisco, Monroy-Valle, Michele, Monterrubio, Eric A, Monterubio Flores, Eric, Moreira, Leila B, Morejon, Alain, Morin, Suzanne N, Motta, Jorge, Neal, William A, Nervi, Flavio, Nieto-Martínez, Ramfis E, Noboa, Oscar A, Ochoa-Avilés, Angélica M, Olinto Anselmo, Maria Teresa, Oliveira, Isabel O, Ono, Lariane M, Ordunez, Pedro, Ortiz, Ana Paula C, Ortiz, Pedro J, Otero, Johanna A, Palloni, Alberto, Peixoto, Sergio Viana, Pereira, Alexandre C, Peres, Marco A, Pérez, Cynthia M, Pichardo, Rafael N, Rangel Reina, Daniel A, Rascon-Pacheco, Ramon A, Revilla, Luis, Ribeiro, Robespierre, Ritti-Dias, Raphael M, Rivera, Juan A, Robitaille, Cynthia, Rodríguez-Villamizar, Laura A, Rojas-Martinez, Rosalba, Roy, Joel GR, Rubinstein, Adolfo, Ruiz-Betancourt, Blanca Sandra, Salazar Martinez, Eduardo, Sánchez-Abanto, Jose, Santos, Ina S, Silva, Diego Augusto Santos, Sbaraini, Mariana, Scazufca, Marcia, Schaan, Beatriz D, Schargrodsky, Herman, Sequera, Victor, Servais, Jennifer, Silva, Antonio M, Soto-Rojas, Victoria E, Sparrenberger, Karen, Stein, Aryeh D, Suárez-Medina, Ramón, Szklo, Moyses, Tebar, William R, Tello, Tania, Tulloch-Reid, Marshall K, Ueda, Peter, Ugel, Eunice, Valdivia, Gonzalo, Velasquez-Melendez, Gustavo, Verstraeten, Roosmarijn, Victora, Cesar G, Wanderley Jr, Rildo S, Wang, Ming-Dong, Wilks, Rainford J, Wong-McClure, Roy A, Younger-Coleman, Novie O, Zapata, Maria Elisa, Zocalo, Yanina, Zuñiga Cisneros, Julio, Danaei, Goodarz, Stevens, Gretchen A, Riley, Leanne M, Ezzati, Majid, and Di Cesare, Mariachiara
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- 2020
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25. The politicizing clinic: insights on ‘the social’ for mental health policy and practice
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Béhague, Dominique P., primary, Gonçalves, Helen, additional, da Cruz, Suélen Henriques, additional, de Cruz, Larissa, additional, Horta, Bernardo L., additional, and Lima, Natália P., additional
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- 2023
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26. High prevalence of symptoms among Brazilian subjects with antibodies against SARS-CoV-2
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Menezes, Ana M. B., Victora, Cesar G., Hartwig, Fernando P., Silveira, Mariângela F., Horta, Bernardo L., Barros, Aluísio J. D., Mesenburg, Marilia A., Wehrmeister, Fernando C., Pellanda, Lúcia C., Dellagostin, Odir A., Struchiner, Cláudio J., Burattini, Marcelo N., Barros, Fernando C., and Hallal, Pedro C.
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- 2021
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27. Population-based surveys of antibodies against SARS-CoV-2 in Southern Brazil
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Silveira, Mariângela F., Barros, Aluísio J. D., Horta, Bernardo L., Pellanda, Lúcia C., Victora, Gabriel D., Dellagostin, Odir A., and Struchiner, Claudio J.
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Immunoglobulin M -- Identification and classification -- Methods ,Epidemics -- Diagnosis -- Brazil ,Sentinel health events -- Methods -- Diagnosis ,Immunoglobulin G -- Identification and classification -- Methods ,Biological sciences ,Health - Abstract
Population-based data on COVID-19 are urgently needed. We report on three rounds of probability sample household surveys in the state of Rio Grande do Sul (Brazil), carried out in nine large municipalities using the Wondfo lateral flow point-of-care test for immunoglobulin M and G antibodies against SARS-CoV-2 ((https://en.wondfo.com.cn/product/wondfo-sars-cov-2-antibody-test-lateral-flow-method-2/)). Before survey use, the assay underwent four validation studies with pooled estimates of sensitivity (84.8%; 95% confidence interval (CI) = 81.4-87.8%) and specificity (99.0%; 95% CI = 97.8-99.7%). We calculated that the seroprevalence was 0.048% (2/4,151; 95% CI = 0.006-0.174) on 11-13 April (round 1), 0.135% (6/4,460; 95% CI = 0.049-0.293%) on 25-27 April (round 2) and 0.222% (10/4,500; 95% CI = 0.107-0.408) on 9-11 May (round 3), with a significant upward trend over the course of the surveys. Of 37 family members of positive individuals, 17 (35%) were also positive. The epidemic is at an early stage in the state, and there is high compliance with social distancing, unlike in other parts of Brazil. Periodic survey rounds will continue to monitor trends until at least the end of September, and our population-based data will inform decisions on preventive policies and health system preparedness at the state level. Three separate rounds of serological surveys in the state of Rio Grande do Sul in Brazil from mid-April to mid-May 2020 show an increase in antibodies specific for SARS-CoV-2 over time., Author(s): Mariângela F. Silveira [sup.1] , Aluísio J. D. Barros [sup.1] , Bernardo L. Horta [sup.1] , Lúcia C. Pellanda [sup.2] , Gabriel D. Victora [sup.3] , Odir A. Dellagostin [...]
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- 2020
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28. Trends in the prevalence of COVID-19 infection in Rio Grande do Sul, Brazil: repeated serological surveys
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Hallal, Pedro Curi, Horta, Bernardo L., Barros, Aluisio J.D., Dellagostin, Odir A., Hartwig, Fernando P., Pellanda, Lucia C., Struchiner, Claudio Jose, Burattini, Marcelo N., da Silveira, Mariangela Freitas, Menezes, Ana M.B., Barros, Fernando C., and Victora, Cesar Gomes
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- 2020
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29. Genomic Ancestry, Self-Rated Health and Its Association with Mortality in an Admixed Population: 10 Year Follow-Up of the Bambui-Epigen (Brazil) Cohort Study of Ageing
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Lima-Costa, M Fernanda, Macinko, James, de Melo Mambrini, Juliana Vaz, Cesar, Cibele C, Peixoto, Sérgio V, Magalhães, Wagner CS, Horta, Bernardo L, Barreto, Mauricio, Castro-Costa, Erico, Firmo, Josélia OA, Proietti, Fernando A, Leal, Thiago Peixoto, Rodrigues, Maira R, Pereira, Alexandre, and Tarazona-Santos, Eduardo
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Epidemiology ,Public Health ,Health Sciences ,Human Society ,Genetics ,Good Health and Well Being ,Aging ,Brazil ,Cohort Studies ,Follow-Up Studies ,Genome ,Human ,Health Status ,Humans ,Self-Assessment ,General Science & Technology - Abstract
BackgroundSelf-rated health (SRH) has strong predictive value for mortality in different contexts and cultures, but there is inconsistent evidence on ethnoracial disparities in SRH in Latin America, possibly due to the complexity surrounding ethnoracial self-classification.Materials/methodsWe used 370,539 Single Nucleotide Polymorphisms (SNPs) to examine the association between individual genomic proportions of African, European and Native American ancestry, and ethnoracial self-classification, with baseline and 10-year SRH trajectories in 1,311 community dwelling older Brazilians. We also examined whether genomic ancestry and ethnoracial self-classification affect the predictive value of SRH for subsequent mortality.ResultsEuropean ancestry predominated among participants, followed by African and Native American (median = 84.0%, 9.6% and 5.3%, respectively); the prevalence of Non-White (Mixed and Black) was 39.8%. Persons at higher levels of African and Native American genomic ancestry, and those self-identified as Non-White, were more likely to report poor health than other groups, even after controlling for socioeconomic conditions and an array of self-reported and objective physical health measures. Increased risks for mortality associated with worse SRH trajectories were strong and remarkably similar (hazard ratio ~3) across all genomic ancestry and ethno-racial groups.ConclusionsOur results demonstrated for the first time that higher levels of African and Native American genomic ancestry--and the inverse for European ancestry--were strongly correlated with worse SRH in a Latin American admixed population. Both genomic ancestry and ethnoracial self-classification did not modify the strong association between baseline SRH or SRH trajectory, and subsequent mortality.
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- 2015
30. SMIM1 absence is associated with reduced energy expenditure and excess weight
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Banasik, Karina, Bay, Jakob, Boldsen, Jens Kjærgaard, Brodersen, Thorsten, Brunak, Søren, Burgdorf, Kristoffer, Chalmer, Mona Ameri, Didriksen, Maria, Dinh, Khoa Manh, Dowsett, Joseph, Erikstrup, Christian, Feenstra, Bjarke, Geller, Frank, Gudbjartsson, Daniel, Hansen, Thomas Folkmann, Hindhede, Lotte, Hjalgrim, Henrik, Jacobsen, Rikke Louise, Jemec, Gregor, Jensen, Bitten Aagaard, Kaspersen, Katrine, Kjerulff, Bertram Dalskov, Kogelman, Lisette, Hørup Larsen, Margit Anita, Louloudis, Ioannis, Lundgaard, Agnete, Susan, Mikkelsen, Christina, Nissen, Ioanna, Nyegaard, Mette, Ostrowski, Sisse Rye, Pedersen, Ole Birger, Henriksen, Alexander Pil, Rohde, Palle Duun, Rostgaard, Klaus, Schwinn, Michael, Stefansson, Kari, Stefánsson, Hreinn, Sørensen, Erik, þorsteinsdóttir, Unnur, Thørner, Lise Wegner, Bruun, Mie Topholm, Ullum, Henrik, Werge, Thomas, Westergaard, David, Chen, Ji, Spracklen, Cassandra N., Marenne, Gaëlle, Varshney, Arushi, Corbin, Laura J., Luan, Jian’an, Willems, Sara M., Wu, Ying, Zhang, Xiaoshuai, Horikoshi, Momoko, Boutin, Thibaud S., Mägi, Reedik, Waage, Johannes, Li-Gao, Ruifang, Katie Chan, Kei Hang, Yao, Jie, Anasanti, Mila D., Chu, Audrey Y., Claringbould, Annique, Heikkinen, Jani, Hong, Jaeyoung, Hottenga, Jouke-Jan, Huo, Shaofeng, Kaakinen, Marika A., Louie, Tin, März, Winfried, Moreno-Macias, Hortensia, Ndungu, Anne, Nelson, Sarah C., Nolte, Ilja M., North, Kari E., Raulerson, Chelsea K., Ray, Debashree, Rohde, Rebecca, Rybin, Denis, Schurmann, Claudia, Sim, Xueling, Southam, Loz, Stewart, Isobel D., Wang, Carol A., Wang, Yujie, Wu, Peitao, Zhang, Weihua, Ahluwalia, Tarunveer S., Appel, Emil V.R., Bielak, Lawrence F., Brody, Jennifer A., Burtt, Noël P., Cabrera, Claudia P., Cade, Brian E., Chai, Jin Fang, Chai, Xiaoran, Chang, Li-Ching, Chen, Chien-Hsiun, Chen, Brian H., Chitrala, Kumaraswamy Naidu, Chiu, Yen-Feng, de Haan, Hugoline G., Delgado, Graciela E., Demirkan, Ayse, Duan, Qing, Engmann, Jorgen, Fatumo, Segun A., Gayán, Javier, Giulianini, Franco, Gong, Jung Ho, Gustafsson, Stefan, Hai, Yang, Hartwig, Fernando P., He, Jing, Heianza, Yoriko, Huang, Tao, Huerta-Chagoya, Alicia, Hwang, Mi Yeong, Jensen, Richard A., Kawaguchi, Takahisa, Kentistou, Katherine A., Kim, Young Jin, Kleber, Marcus E., Kooner, Ishminder K., Lai, Shuiqing, Lange, Leslie A., Langefeld, Carl D., Lauzon, Marie, Li, Man, Ligthart, Symen, Liu, Jun, Loh, Marie, Long, Jirong, Lyssenko, Valeriya, Mangino, Massimo, Marzi, Carola, Montasser, May E., Nag, Abhishek, Nakatochi, Masahiro, Noce, Damia, Noordam, Raymond, Pistis, Giorgio, Preuss, Michael, Raffield, Laura, Rasmussen-Torvik, Laura J., Rich, Stephen S., Robertson, Neil R., Rueedi, Rico, Ryan, Kathleen, Sanna, Serena, Saxena, Richa, Schraut, Katharina E., Sennblad, Bengt, Setoh, Kazuya, Smith, Albert V., Southam, Lorraine, Sparsø, Thomas, Strawbridge, Rona J., Takeuchi, Fumihiko, Tan, Jingyi, Trompet, Stella, van den Akker, Erik, van der Most, Peter J., Verweij, Niek, Vogel, Mandy, Wang, Heming, Wang, Chaolong, Wang, Nan, Warren, Helen R., Wen, Wanqing, Wilsgaard, Tom, Wong, Andrew, Wood, Andrew R., Xie, Tian, Zafarmand, Mohammad Hadi, Zhao, Jing-Hua, Zhao, Wei, Amin, Najaf, Arzumanyan, Zorayr, Astrup, Arne, Bakker, Stephan J.L., Baldassarre, Damiano, Beekman, Marian, Bergman, Richard N., Bertoni, Alain, Blüher, Matthias, Bonnycastle, Lori L., Bornstein, Stefan R., Bowden, Donald W., Cai, Qiuyin, Campbell, Archie, Campbell, Harry, Chang, Yi Cheng, de Geus, Eco J.C., Dehghan, Abbas, Du, Shufa, Eiriksdottir, Gudny, Farmaki, Aliki Eleni, Frånberg, Mattias, Fuchsberger, Christian, Gao, Yutang, Gjesing, Anette P., Goel, Anuj, Han, Sohee, Hartman, Catharina A., Herder, Christian, Hicks, Andrew A., Hsieh, Chang-Hsun, Hsueh, Willa A., Ichihara, Sahoko, Igase, Michiya, Ikram, M. Arfan, Johnson, W. Craig, Jørgensen, Marit E., Joshi, Peter K., Kalyani, Rita R., Kandeel, Fouad R., Katsuya, Tomohiro, Khor, Chiea Chuen, Kiess, Wieland, Kolcic, Ivana, Kuulasmaa, Teemu, Kuusisto, Johanna, Läll, Kristi, Lam, Kelvin, Lawlor, Deborah A., Lee, Nanette R., Lemaitre, Rozenn N., Li, Honglan, Lin, Shih-Yi, Lindström, Jaana, Linneberg, Allan, Liu, Jianjun, Lorenzo, Carlos, Matsubara, Tatsuaki, Matsuda, Fumihiko, Mingrone, Geltrude, Mooijaart, Simon, Moon, Sanghoon, Nabika, Toru, Nadkarni, Girish N., Nadler, Jerry L., Nelis, Mari, Neville, Matt J., Norris, Jill M., Ohyagi, Yasumasa, Peters, Annette, Peyser, Patricia A., Polasek, Ozren, Qi, Qibin, Raven, Dennis, Reilly, Dermot F., Reiner, Alex, Rivideneira, Fernando, Roll, Kathryn, Rudan, Igor, Sabanayagam, Charumathi, Sandow, Kevin, Sattar, Naveed, Schürmann, Annette, Shi, Jinxiu, Stringham, Heather M., Taylor, Kent D., Teslovich, Tanya M., Thuesen, Betina, Timmers, Paul R.H.J., Tremoli, Elena, Tsai, Michael Y., Uitterlinden, Andre, van Dam, Rob M., van Heemst, Diana, van Hylckama Vlieg, Astrid, Van Vliet-Ostaptchouk, Jana V., Vangipurapu, Jagadish, Vestergaard, Henrik, Wang, Tao, Willems van Dijk, Ko, Zemunik, Tatijana, Abecasis, Goncalo R., Adair, Linda S., Aguilar-Salinas, Carlos Alberto, Alarcón-Riquelme, Marta E., An, Ping, Aviles-Santa, Larissa, Becker, Diane M., Beilin, Lawrence J., Bergmann, Sven, Bisgaard, Hans, Black, Corri, Boehnke, Michael, Boerwinkle, Eric, Böhm, Bernhard O., Bønnelykke, Klaus, Boomsma, D.I., Bottinger, Erwin P., Buchanan, Thomas A., Canouil, Mickaël, Caulfield, Mark J., Chambers, John C., Chasman, Daniel I., Ida Chen, Yii-Der, Cheng, Ching-Yu, Collins, Francis S., Correa, Adolfo, Cucca, Francesco, Janaka de Silva, H., Dedoussis, George, Elmståhl, Sölve, Evans, Michele K., Ferrannini, Ele, Ferrucci, Luigi, Florez, Jose C., Franks, Paul W., Frayling, Timothy M., Froguel, Philippe, Gigante, Bruna, Goodarzi, Mark O., Gordon-Larsen, Penny, Grallert, Harald, Grarup, Niels, Grimsgaard, Sameline, Groop, Leif, Gudnason, Vilmundur, Guo, Xiuqing, Hamsten, Anders, Hansen, Torben, Hayward, Caroline, Heckbert, Susan R., Horta, Bernardo L., Huang, Wei, Ingelsson, Erik, James, Pankow S., Jarvelin, Marjo-Ritta, Jonas, Jost B., Jukema, J. Wouter, Kaleebu, Pontiano, Kaplan, Robert, Kardia, Sharon L.R., Kato, Norihiro, Keinanen-Kiukaanniemi, Sirkka M., Kim, Bong-Jo, Kivimaki, Mika, Koistinen, Heikki A., Kooner, Jaspal S., Körner, Antje, Kovacs, Peter, Kuh, Diana, Kumari, Meena, Kutalik, Zoltan, Laakso, Markku, Lakka, Timo A., Launer, Lenore J., Leander, Karin, Li, Huaixing, Lin, Xu, Lind, Lars, Lindgren, Cecilia, Liu, Simin, Loos, Ruth J.F., Magnusson, Patrik K.E., Mahajan, Anubha, Metspalu, Andres, Mook-Kanamori, Dennis O., Mori, Trevor A., Munroe, Patricia B., Njølstad, Inger, O'Connell, Jeffrey R., Oldehinkel, Albertine J., Ong, Ken K., Padmanabhan, Sandosh, Palmer, Colin N.A., Palmer, Nicholette D., Pedersen, Oluf, Pennell, Craig E., Porteous, David J., Pramstaller, Peter P., Province, Michael A., Psaty, Bruce M., Qi, Lu, Raffel, Leslie J., Rauramaa, Rainer, Redline, Susan, Ridker, Paul M., Rosendaal, Frits R., Saaristo, Timo E., Sandhu, Manjinder, Saramies, Jouko, Schneiderman, Neil, Schwarz, Peter, Scott, Laura J., Selvin, Elizabeth, Sever, Peter, Shu, Xiao-Ou, Slagboom, P. Eline, Small, Kerrin S., Smith, Blair H., Snieder, Harold, Sofer, Tamar, Sørensen, Thorkild I.A., Spector, Tim D., Stanton, Alice, Steves, Claire J., Stumvoll, Michael, Sun, Liang, Tabara, Yasuharu, Tai, E. Shyong, Timpson, Nicholas J., Tönjes, Anke, Tuomilehto, Jaakko, Tusie, Teresa, Uusitupa, Matti, van der Harst, Pim, van Duijn, Cornelia, Vitart, Veronique, Vollenweider, Peter, Vrijkotte, Tanja G.M., Wagenknecht, Lynne E., Walker, Mark, Wang, Ya X., Wareham, Nick J., Watanabe, Richard M., Watkins, Hugh, Wei, Wen B., Wickremasinghe, Ananda R., Willemsen, Gonneke, Wilson, James F., Wong, Tien-Yin, Wu, Jer-Yuarn, Xiang, Anny H., Yanek, Lisa R., Yengo, Loïc, Yokota, Mitsuhiro, Zeggini, Eleftheria, Zheng, Wei, Zonderman, Alan B., Rotter, Jerome I., Gloyn, Anna L., McCarthy, Mark I., Dupuis, Josée, Meigs, James B., Scott, Robert A., Prokopenko, Inga, Leong, Aaron, Liu, Ching-Ti, Parker, Stephen C.J., Mohlke, Karen L., Langenberg, Claudia, Wheeler, Eleanor, Morris, Andrew P., Barroso, Inês, Stefanucci, Luca, Moslemi, Camous, Tomé, Ana R., Virtue, Samuel, Bidault, Guillaume, Gleadall, Nicholas S., Watson, Laura P.E., Kwa, Jing E., Burden, Frances, Farrow, Samantha, Võsa, Urmo, Burling, Keith, Walker, Lindsay, Ord, John, Barker, Peter, Warner, James, Frary, Amy, Renhstrom, Karola, Ashford, Sofie E., Piper, Jo, Biggs, Gail, Erber, Wendy N., Hoffman, Gary J., Schoenmakers, Nadia, Rieneck, Klaus, Dziegiel, Morten H., Azzu, Vian, Vacca, Michele, Aparicio, Hugo Javier, Hui, Qin, Cho, Kelly, Sun, Yan V., Wilson, Peter W., Bayraktar, Omer A., Vidal-Puig, Antonio, Ostrowski, Sisse R., Astle, William J., Olsson, Martin L., Storry, Jill R., Pedersen, Ole B., Ouwehand, Willem H., Chatterjee, Krishna, Vuckovic, Dragana, and Frontini, Mattia
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- 2024
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31. Association of pulse wave velocity with body fat measures at 30 y of age
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Vianna, Carolina Avila, Horta, Bernardo L., Gonzalez, Maria Cristina, França, Giovanny Vinícius A, Gigante, Denise P., and Barros, Fernando L.
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- 2019
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32. Treatment outcomes in tuberculosis patients with diabetes: a polytomous analysis using Brazilian surveillance system.
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Reis-Santos, Bárbara, Gomes, Teresa, Locatelli, Rodrigo, de Oliveira, Elizabete R, Sanchez, Mauro N, Horta, Bernardo L, Riley, Lee W, and Maciel, Ethel L
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Humans ,Tuberculosis ,Diabetes Complications ,Treatment Outcome ,Regression Analysis ,Drug Resistance ,Multiple ,Adolescent ,Adult ,Middle Aged ,Child ,Child ,Preschool ,Infant ,Infant ,Newborn ,Brazil ,Female ,Male ,Young Adult ,Epidemiological Monitoring ,Drug Resistance ,Multiple ,Preschool ,Newborn ,General Science & Technology - Abstract
BackgroundThe impact of non-communicable diseases on tuberculosis incidence has received significant attention. It has been suggested that the risk of tuberculosis is higher among subjects with diabetes and these subjects also has poor TB treatment outcomes.This study was aimed at assessing the socio-demographic and clinical factors that may influence different outcome of TB in patients with DM (TB-DM) identified in the Brazilian national database from 2001 to 2011.MethodsTB-DM cases reported in the Brazilian information system were identified and compared.Covariates associated with the outcomes of interest (cure, default, deaths, and development of TB MDR) were included in a hierarchical regression model.ResultsTB-DM cases increased from 380/100,000/year in 2001 to 6,150/100,000/year in 2011. Some of the main associations found are pointed. The odds of default was higher among those in the age group 20-39 years (OR = 2.07, 95%CI 1.32-3.24); alcoholics (OR = 2.17, 95%CI 1.86-2.54), and HIV/AIDS (OR = 2.16, 95%CI 1.70-2.74);positive monitoring smear (OR = 1.94, 95%CI 1.55-2.43); prior default (OR = 5.41, 95%CI 4.47-6.54), and unknown type of treatment (OR = 3.33, 95%CI 1.54-7.22). The odds of death was greater for subjects ≥60 years old (OR = 2.74, 95%CI 1.74-4.29); institutionalized in shelter (OR = 2.69, 95%CI 1.07-6.77); alcoholics (OR = 2.70, 95%CI 2.27-3.22); HIV/AIDS (OR = 2.87, 95%CI 2.13-3.86); pulmonary+extrapulmonary TB (OR = 2.49, 95%CI 1.79-3.46); with unknown type of treatment (OR = 14.12, 95%CI 7.04-28.32).Development of MDR TB was more related to relapse (OR = 9.60, 95%CI 6.07-15.14);previous default (OR = 17.13, 95%CI 9.58-30.63); and transfer of treatment center (OR = 7.87, 95%CI 4.74-13.07).ConclusionsOlder subjects and those with comorbidities and with a previous treatment of TB had poorest outcomes. TB control program in Brazil will need to expand efforts to focus on treatment of TB-DM patients to improve their cure rates in order to achieve the goals of tuberculosis elimination.
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- 2014
33. Gene-educational attainment interactions in a multi-population genome-wide meta-analysis identify novel lipid loci
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de las Fuentes, Lisa, primary, Schwander, Karen L., additional, Brown, Michael R., additional, Bentley, Amy R., additional, Winkler, Thomas W., additional, Sung, Yun Ju, additional, Munroe, Patricia B., additional, Miller, Clint L., additional, Aschard, Hugo, additional, Aslibekyan, Stella, additional, Bartz, Traci M., additional, Bielak, Lawrence F., additional, Chai, Jin Fang, additional, Cheng, Ching-Yu, additional, Dorajoo, Rajkumar, additional, Feitosa, Mary F., additional, Guo, Xiuqing, additional, Hartwig, Fernando P., additional, Horimoto, Andrea, additional, Kolčić, Ivana, additional, Lim, Elise, additional, Liu, Yongmei, additional, Manning, Alisa K., additional, Marten, Jonathan, additional, Musani, Solomon K., additional, Noordam, Raymond, additional, Padmanabhan, Sandosh, additional, Rankinen, Tuomo, additional, Richard, Melissa A., additional, Ridker, Paul M., additional, Smith, Albert V., additional, Vojinovic, Dina, additional, Zonderman, Alan B., additional, Alver, Maris, additional, Boissel, Mathilde, additional, Christensen, Kaare, additional, Freedman, Barry I., additional, Gao, Chuan, additional, Giulianini, Franco, additional, Harris, Sarah E., additional, He, Meian, additional, Hsu, Fang-Chi, additional, Kühnel, Brigitte, additional, Laguzzi, Federica, additional, Li, Xiaoyin, additional, Lyytikäinen, Leo-Pekka, additional, Nolte, Ilja M., additional, Poveda, Alaitz, additional, Rauramaa, Rainer, additional, Riaz, Muhammad, additional, Robino, Antonietta, additional, Sofer, Tamar, additional, Takeuchi, Fumihiko, additional, Tayo, Bamidele O., additional, van der Most, Peter J., additional, Verweij, Niek, additional, Ware, Erin B., additional, Weiss, Stefan, additional, Wen, Wanqing, additional, Yanek, Lisa R., additional, Zhan, Yiqiang, additional, Amin, Najaf, additional, Arking, Dan E., additional, Ballantyne, Christie, additional, Boerwinkle, Eric, additional, Brody, Jennifer A., additional, Broeckel, Ulrich, additional, Campbell, Archie, additional, Canouil, Mickaël, additional, Chai, Xiaoran, additional, Chen, Yii-Der Ida, additional, Chen, Xu, additional, Chitrala, Kumaraswamy Naidu, additional, Concas, Maria Pina, additional, de Faire, Ulf, additional, de Mutsert, Renée, additional, de Silva, H. Janaka, additional, de Vries, Paul S., additional, Do, Ahn, additional, Faul, Jessica D., additional, Fisher, Virginia, additional, Floyd, James S., additional, Forrester, Terrence, additional, Friedlander, Yechiel, additional, Girotto, Giorgia, additional, Gu, C. Charles, additional, Hallmans, Göran, additional, Heikkinen, Sami, additional, Heng, Chew-Kiat, additional, Homuth, Georg, additional, Hunt, Steven, additional, Ikram, M. Arfan, additional, Jacobs, David R., additional, Kavousi, Maryam, additional, Khor, Chiea Chuen, additional, Kilpeläinen, Tuomas O., additional, Koh, Woon-Puay, additional, Komulainen, Pirjo, additional, Langefeld, Carl D., additional, Liang, Jingjing, additional, Liu, Kiang, additional, Liu, Jianjun, additional, Lohman, Kurt, additional, Mägi, Reedik, additional, Manichaikul, Ani W., additional, McKenzie, Colin A., additional, Meitinger, Thomas, additional, Milaneschi, Yuri, additional, Nauck, Matthias, additional, Nelson, Christopher P., additional, O’Connell, Jeffrey R., additional, Palmer, Nicholette D., additional, Pereira, Alexandre C., additional, Perls, Thomas, additional, Peters, Annette, additional, Polašek, Ozren, additional, Raitakari, Olli T., additional, Rice, Kenneth, additional, Rice, Treva K., additional, Rich, Stephen S., additional, Sabanayagam, Charumathi, additional, Schreiner, Pamela J., additional, Shu, Xiao-Ou, additional, Sidney, Stephen, additional, Sims, Mario, additional, Smith, Jennifer A., additional, Starr, John M., additional, Strauch, Konstantin, additional, Tai, E. Shyong, additional, Taylor, Kent D., additional, Tsai, Michael Y., additional, Uitterlinden, André G., additional, van Heemst, Diana, additional, Waldenberger, Melanie, additional, Wang, Ya-Xing, additional, Wei, Wen-Bin, additional, Wilson, Gregory, additional, Xuan, Deng, additional, Yao, Jie, additional, Yu, Caizheng, additional, Yuan, Jian-Min, additional, Zhao, Wei, additional, Becker, Diane M., additional, Bonnefond, Amélie, additional, Bowden, Donald W., additional, Cooper, Richard S., additional, Deary, Ian J., additional, Divers, Jasmin, additional, Esko, Tõnu, additional, Franks, Paul W., additional, Froguel, Philippe, additional, Gieger, Christian, additional, Jonas, Jost B., additional, Kato, Norihiro, additional, Lakka, Timo A., additional, Leander, Karin, additional, Lehtimäki, Terho, additional, Magnusson, Patrik K. E., additional, North, Kari E., additional, Ntalla, Ioanna, additional, Penninx, Brenda, additional, Samani, Nilesh J., additional, Snieder, Harold, additional, Spedicati, Beatrice, additional, van der Harst, Pim, additional, Völzke, Henry, additional, Wagenknecht, Lynne E., additional, Weir, David R., additional, Wojczynski, Mary K., additional, Wu, Tangchun, additional, Zheng, Wei, additional, Zhu, Xiaofeng, additional, Bouchard, Claude, additional, Chasman, Daniel I., additional, Evans, Michele K., additional, Fox, Ervin R., additional, Gudnason, Vilmundur, additional, Hayward, Caroline, additional, Horta, Bernardo L., additional, Kardia, Sharon L. R., additional, Krieger, Jose Eduardo, additional, Mook-Kanamori, Dennis O., additional, Peyser, Patricia A., additional, Province, Michael M., additional, Psaty, Bruce M., additional, Rudan, Igor, additional, Sim, Xueling, additional, Smith, Blair H., additional, van Dam, Rob M., additional, van Duijn, Cornelia M., additional, Wong, Tien Yin, additional, Arnett, Donna K., additional, Rao, Dabeeru C., additional, Gauderman, James, additional, Liu, Ching-Ti, additional, Morrison, Alanna C., additional, Rotter, Jerome I., additional, and Fornage, Myriam, additional
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- 2023
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34. Prevalence and patterns of multimorbidity among tuberculosis patients in Brazil: a cross-sectional study
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Reis-Santos, Bárbara, Gomes, Teresa, Macedo, Laylla R, Horta, Bernardo L, Riley, Lee W, and Maciel, Ethel L
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Abstract Introduction The number of subjects with tuberculosis (TB) presenting with co-occurrence of multiple chronic medical conditions, or multimorbidity (MM) is increasing in Brazil. This manuscript aimed to characterize subjects with TB, according to their MM status and to analyse factors associated with TB treatment outcomes. Methods This is a cross-sectional study that included 39,881 TB subjects reported in Brazil, in 2011. MM were defined as any (two or more) occurrence of chronic medical conditions in a TB patient (TB–MM). Data analysis was performed by hierarchical logistic regression models comparing TBMM with those with only TB. Results Of the reported TB cases in 2011, 454 (1.14%) had MM. The subjects in the age group 40–59 years (OR: 17.89; 95% CI, 5.71-56.03) and those ≥ 60 years (OR: 44.11; 95% CI, 14.09-138.06) were more likely to develop TB–MM. The TB–MM subjects were less likely to be male (OR: 0.63; 95% CI, 0.52-0.76), institutionalized (OR: 0.59; 95% CI, 0.23-0.80) and live in rural areas (OR: 0.63; 95% CI, 0.42-0.95). Death from causes other than TB was higher among TB–MM subjects (OR: 1.76; 95% CI, 1.36-2.28). Of 454 TB–MM subjects 302 (66.5%) were cured and 152 (33.5%) were not cured. The odds of not being cured was 1.55 (95% CI, 1.04-2.32) among males, 2.85 (95% CI, 1.12-7.28) among institutionalized subjects, and 3.93 (IC 95%, 1.86-8.30) among those who were infected with HIV. TB retreatment after previous abandonment (OR: 7.53; 95% CI, 2.58-21.97) and transfer from a treatment site (OR: 2.76; 95% CI, 1.20-6.38) were higher for subjects not cured compared to those who were cured. Conclusions While TB is well recognized to be a disease engendered by social inequity, we found that even among TB patients, those who have MM have greater inequity in terms of socioeconomic status and adverse clinical outcomes. Addressing the problem of TB and TB–MM requires a multisectorial approach that includes health and social service organizations.
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- 2013
35. Genetic structure of pharmacogenetic biomarkers in Brazil inferred from a systematic review and population-based cohorts: a RIBEF/EPIGEN-Brazil initiative
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Rodrigues-Soares, Fernanda, Kehdy, Fernanda S. G., Sampaio-Coelho, Julia, Andrade, Poliana X. C., Céspedes-Garro, Carolina, Zolini, Camila, Aquino, Marla M., Barreto, Mauricio L., Horta, Bernardo L., Lima-Costa, Maria Fernanda, Pereira, Alexandre C., LLerena, Adrián, and Tarazona-Santos, Eduardo
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- 2018
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36. Worldwide trends in body-mass index, underweight, overweight, and obesity from 1975 to 2016: a pooled analysis of 2416 population-based measurement studies in 128·9 million children, adolescents, and adults
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Abarca-Gómez, Leandra, Abdeen, Ziad A, Hamid, Zargar Abdul, Abu-Rmeileh, Niveen M, Acosta-Cazares, Benjamin, Acuin, Cecilia, Adams, Robert J, Aekplakorn, Wichai, Afsana, Kaosar, Aguilar-Salinas, Carlos A, Agyemang, Charles, Ahmadvand, Alireza, Ahrens, Wolfgang, Ajlouni, Kamel, Akhtaeva, Nazgul, Al-Hazzaa, Hazzaa M, Al-Othman, Amani Rashed, Al-Raddadi, Rajaa, Al Buhairan, Fadia, Al Dhukair, Shahla, Ali, Mohamed M, Ali, Osman, Alkerwi, Ala'a, Alvarez-Pedrerol, Mar, Aly, Eman, Amarapurkar, Deepak N, Amouyel, Philippe, Amuzu, Antoinette, Andersen, Lars Bo, Anderssen, Sigmund A, Andrade, Dolores S, Ängquist, Lars H, Anjana, Ranjit Mohan, Aounallah-Skhiri, Hajer, Araújo, Joana, Ariansen, Inger, Aris, Tahir, Arlappa, Nimmathota, Arveiler, Dominique, Aryal, Krishna K, Aspelund, Thor, Assah, Felix K, Assunção, Maria Cecília F, Aung, May Soe, Avdicová, Mária, Azevedo, Ana, Azizi, Fereidoun, Babu, Bontha V, Bahijri, Suhad, Baker, Jennifer L, Balakrishna, Nagalla, Bamoshmoosh, Mohamed, Banach, Maciej, Bandosz, Piotr, Banegas, José R, Barbagallo, Carlo M, Barceló, Alberto, Barkat, Amina, Barros, Aluisio JD, Barros, Mauro VG, Bata, Iqbal, Batieha, Anwar M, Batista, Rosangela L, Batyrbek, Assembekov, Baur, Louise A, Beaglehole, Robert, Romdhane, Habiba Ben, Benedics, Judith, Benet, Mikhail, Bennett, James E, Bernabe-Ortiz, Antonio, Bernotiene, Gailute, Bettiol, Heloisa, Bhagyalaxmi, Aroor, Bharadwaj, Sumit, Bhargava, Santosh K, Bhatti, Zaid, Bhutta, Zulfiqar A, Bi, Hongsheng, Bi, Yufang, Biehl, Anna, Bikbov, Mukharram, Bista, Bihungum, Bjelica, Dusko J, Bjerregaard, Peter, Bjertness, Espen, Bjertness, Marius B, Björkelund, Cecilia, Blokstra, Anneke, Bo, Simona, Bobak, Martin, Boddy, Lynne M, Boehm, Bernhard O, Boeing, Heiner, Boggia, Jose G, Boissonnet, Carlos P, Bonaccio, Marialaura, Bongard, Vanina, Bovet, Pascal, Braeckevelt, Lien, Braeckman, Lutgart, Bragt, Marjolijn CE, Brajkovich, Imperia, Branca, Francesco, Breckenkamp, Juergen, Breda, João, Brenner, Hermann, Brewster, Lizzy M, Brian, Garry R, Brinduse, Lacramioara, Bruno, Graziella, Bueno-de-Mesquita, H B(as), Bugge, Anna, Buoncristiano, Marta, Burazeri, Genc, Burns, Con, de León, Antonio Cabrera, Cacciottolo, Joseph, Cai, Hui, Cama, Tilema, Cameron, Christine, Camolas, José, Can, Günay, Cândido, Ana Paula C, Capanzana, Mario, Capuano, Vincenzo, Cardoso, Viviane C, Carlsson, Axel C, Carvalho, Maria J, Casanueva, Felipe F, Casas, Juan-Pablo, Caserta, Carmelo A, Chamukuttan, Snehalatha, Chan, Angelique W, Chan, Queenie, Chaturvedi, Himanshu K, Chaturvedi, Nishi, Chen, Chien-Jen, Chen, Fangfang, Chen, Huashuai, Chen, Shuohua, Chen, Zhengming, Cheng, Ching-Yu, Chetrit, Angela, Chikova-Iscener, Ekaterina, Chiolero, Arnaud, Chiou, Shu-Ti, Chirita-Emandi, Adela, Chirlaque, María-Dolores, Cho, Belong, Cho, Yumi, Christensen, Kaare, Christofaro, Diego G, Chudek, Jerzy, Cifkova, Renata, Cinteza, Eliza, Claessens, Frank, Clays, Els, Concin, Hans, Confortin, Susana C, Cooper, Cyrus, Cooper, Rachel, Coppinger, 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37. Worldwide trends in blood pressure from 1975 to 2015: a pooled analysis of 1479 population-based measurement studies with 19·1 million participants
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Zimmermann, Esther, and Zuñiga Cisneros, Julio
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38. Author Correction: Changes in Infant and Neonatal Mortality and Associated Factors in Eight Cohorts from Three Brazilian Cities
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Carvalho, Carolina A., da Silva, Antônio A. M., Victora, César, Goldani, Marcelo, Bettiol, Heloísa, Thomaz, Erika Barbara Abreu Fonseca, Barros, Fernando, Horta, Bernardo L., Menezes, Ana, Cardoso, Viviane, Cavalli, Ricardo Carvalho, Santos, Iná, Batista, Rosângela F. L., Simões, Vanda Maria, Barbieri, Marco, and Barros, Aluisio
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- 2020
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39. Changes in Infant and Neonatal Mortality and Associated Factors in Eight Cohorts from Three Brazilian Cities
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Carvalho, Carolina A., Silva, Antônio A. M. da, Victora, César, Goldani, Marcelo, Bettiol, Heloísa, Thomaz, Erika Barbara Abreu Fonseca, Barros, Fernando, Horta, Bernardo L., Menezes, Ana, Cardoso, Viviane, Cavalli, Ricardo Carvalho, Santos, Iná, Batista, Rosângela F. L., Simões, Vanda Maria, Barbieri, Marco, and Barros, Aluisio
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- 2020
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40. Prenatal and birth predictors of objectively measured physical activity and sedentary time in three population-based birth cohorts in Brazil
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Ding, Ding, Mielke, Gregore I., Silva, Inacio Crochemore M., Wehrmeister, Fernando C., Horta, Bernardo L., Brage, Soren, Hallal, Pedro C., and Ekelund, Ulf
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- 2020
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41. Social inequalities in mental disorders and substance misuse in young adults: A birth cohort study in Southern Brazil
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Barros, Fernando C., Matijasevich, Alicia, Santos, Iná S., Horta, Bernardo L., da Silva, Bruna Gonçalves C., Munhoz, Tiago N., Fazel, Seena, Stein, Alan, Pearson, Rebecca M., Anselmi, Luciana, and Rohde, Luis Augusto
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- 2018
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42. Gene-educational attainment interactions in a multi-population genome-wide meta-analysis identify novel lipid loci
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Shyong, Taylor, Kent D., Tsai, Michael Y., Uitterlinden, André G., van Heemst, Diana, Waldenberger, Melanie, Wang, Ya Xing, Wei, Wen Bin, Wilson, Gregory, Xuan, Deng, Yao, Jie, Yu, Caizheng, Yuan, Jian Min, Zhao, Wei, Becker, Diane M., Bonnefond, Amélie, Bowden, Donald W., Cooper, Richard S., Deary, Ian J., Divers, Jasmin, Esko, Tõnu, Franks, Paul W., Froguel, Philippe, Gieger, Christian, Jonas, Jost B., Kato, Norihiro, Lakka, Timo A., Leander, Karin, Lehtimäki, Terho, Magnusson, Patrik K.E., North, Kari E., Ntalla, Ioanna, Penninx, Brenda, Samani, Nilesh J., Snieder, Harold, Spedicati, Beatrice, van der Harst, Pim, Völzke, Henry, Wagenknecht, Lynne E., Weir, David R., Wojczynski, Mary K., Wu, Tangchun, Zheng, Wei, Zhu, Xiaofeng, Bouchard, Claude, Chasman, Daniel I., Evans, Michele K., Fox, Ervin R., Gudnason, Vilmundur, Hayward, Caroline, Horta, Bernardo L., Kardia, Sharon L.R., Krieger, Jose Eduardo, Mook-Kanamori, Dennis O., Peyser, Patricia A., Province, Michael M., Psaty, Bruce M., Rudan, Igor, Sim, Xueling, Smith, Blair H., van Dam, Rob M., van Duijn, Cornelia M., Wong, Tien Yin, Arnett, Donna K., Rao, Dabeeru C., Gauderman, James, Liu, Ching Ti, Morrison, Alanna C., Rotter, Jerome I., Fornage, Myriam, de las Fuentes, Lisa, Schwander, Karen L., Brown, Michael R., Bentley, Amy R., Winkler, Thomas W., Sung, Yun Ju, Munroe, Patricia B., Miller, Clint L., Aschard, Hugo, Aslibekyan, Stella, Bartz, Traci M., Bielak, Lawrence F., Chai, Jin Fang, Cheng, Ching Yu, Dorajoo, Rajkumar, Feitosa, Mary F., Guo, Xiuqing, Hartwig, Fernando P., Horimoto, Andrea, Kolčić, Ivana, Lim, Elise, Liu, Yongmei, Manning, Alisa K., Marten, Jonathan, Musani, Solomon K., Noordam, Raymond, Padmanabhan, Sandosh, Rankinen, Tuomo, Richard, Melissa A., Ridker, Paul M., Smith, Albert V., Vojinovic, Dina, Zonderman, Alan B., Alver, Maris, Boissel, Mathilde, Christensen, Kaare, Freedman, Barry I., Gao, Chuan, Giulianini, Franco, Harris, Sarah E., He, Meian, Hsu, Fang Chi, Kühnel, Brigitte, Laguzzi, Federica, Li, Xiaoyin, Lyytikäinen, Leo Pekka, Nolte, Ilja M., Poveda, Alaitz, Rauramaa, Rainer, Riaz, Muhammad, Robino, Antonietta, Sofer, Tamar, Takeuchi, Fumihiko, Tayo, Bamidele O., van der Most, Peter J., Verweij, Niek, Ware, Erin B., Weiss, Stefan, Wen, Wanqing, Yanek, Lisa R., Zhan, Yiqiang, Amin, Najaf, Arking, Dan E., Ballantyne, Christie, Boerwinkle, Eric, Brody, Jennifer A., Broeckel, Ulrich, Campbell, Archie, Canouil, Mickaël, Chai, Xiaoran, Chen, Yii Der Ida, Chen, Xu, Chitrala, Kumaraswamy Naidu, Concas, Maria Pina, de Faire, Ulf, de Mutsert, Renée, de Silva, H. Janaka, de Vries, Paul S., Do, Ahn, Faul, Jessica D., Fisher, Virginia, Floyd, James S., Forrester, Terrence, Friedlander, Yechiel, Girotto, Giorgia, Gu, C. Charles, Hallmans, Göran, Heikkinen, Sami, Heng, Chew Kiat, Homuth, Georg, Hunt, Steven, Ikram, M. Arfan, Jacobs, David R., Kavousi, Maryam, Khor, Chiea Chuen, Kilpeläinen, Tuomas O., Koh, Woon Puay, Komulainen, Pirjo, Langefeld, Carl D., Liang, Jingjing, Liu, Kiang, Liu, Jianjun, Lohman, Kurt, Mägi, Reedik, Manichaikul, Ani W., McKenzie, Colin A., Meitinger, Thomas, Milaneschi, Yuri, Nauck, Matthias, Nelson, Christopher P., O’Connell, Jeffrey R., Palmer, Nicholette D., Pereira, Alexandre C., Perls, Thomas, Peters, Annette, Polašek, Ozren, Raitakari, Olli T., Rice, Kenneth, Rice, Treva K., Rich, Stephen S., Sabanayagam, Charumathi, Schreiner, Pamela J., Shu, Xiao Ou, Sidney, Stephen, Sims, Mario, Smith, Jennifer A., Starr, John M., Strauch, Konstantin, Tai, E. Shyong, Taylor, Kent D., Tsai, Michael Y., Uitterlinden, André G., van Heemst, Diana, Waldenberger, Melanie, Wang, Ya Xing, Wei, Wen Bin, Wilson, Gregory, Xuan, Deng, Yao, Jie, Yu, Caizheng, Yuan, Jian Min, Zhao, Wei, Becker, Diane M., Bonnefond, Amélie, Bowden, Donald W., Cooper, Richard S., Deary, Ian J., Divers, Jasmin, Esko, Tõnu, Franks, Paul W., Froguel, Philippe, Gieger, Christian, Jonas, Jost B., Kato, Norihiro, Lakka, Timo A., Leander, Karin, Lehtimäki, Terho, Magnusson, Patrik K.E., North, Kari E., Ntalla, Ioanna, Penninx, Brenda, Samani, Nilesh J., Snieder, Harold, Spedicati, Beatrice, van der Harst, Pim, Völzke, Henry, Wagenknecht, Lynne E., Weir, David R., Wojczynski, Mary K., Wu, Tangchun, Zheng, Wei, Zhu, Xiaofeng, Bouchard, Claude, Chasman, Daniel I., Evans, Michele K., Fox, Ervin R., Gudnason, Vilmundur, Hayward, Caroline, Horta, Bernardo L., Kardia, Sharon L.R., Krieger, Jose Eduardo, Mook-Kanamori, Dennis O., Peyser, Patricia A., Province, Michael M., Psaty, Bruce M., Rudan, Igor, Sim, Xueling, Smith, Blair H., van Dam, Rob M., van Duijn, Cornelia M., Wong, Tien Yin, Arnett, Donna K., Rao, Dabeeru C., Gauderman, James, Liu, Ching Ti, Morrison, Alanna C., Rotter, Jerome I., and Fornage, Myriam
- Abstract
Introduction: Educational attainment, widely used in epidemiologic studies as a surrogate for socioeconomic status, is a predictor of cardiovascular health outcomes. Methods:A two-stage genome-wide meta-analysis of low-density lipoprotein cholesterol (LDL), high-density lipoprotein cholesterol (HDL), and triglyceride (TG) levels was performed while accounting for gene-educational attainment interactions in up to 226,315 individuals from five population groups. We considered two educational attainment variables: “Some College” (yes/no, for any education beyond high school) and “Graduated College” (yes/no, for completing a 4-year college degree). Genome-wide significant (p < 5 × 10−8) and suggestive (p < 1 × 10−6) variants were identified in Stage 1 (in up to 108,784 individuals) through genome-wide analysis, and those variants were followed up in Stage 2 studies (in up to 117,531 individuals). Results: In combined analysis of Stages 1 and 2, we identified 18 novel lipid loci (nine for LDL, seven for HDL, and two for TG) by two degree-of-freedom (2 DF) joint tests of main and interaction effects. Four loci showed significant interaction with educational attainment. Two loci were significant only in cross-population analyses. Several loci include genes with known or suggested roles in adipose (FOXP1, MBOAT4, SKP2, STIM1, STX4), brain (BRI3, FILIP1, FOXP1, LINC00290, LMTK2, MBOAT4, MYO6, SENP6, SRGAP3, STIM1, TMEM167A, TMEM30A), and liver (BRI3, FOXP1) biology, highlighting the potential importance of brain-adipose-liver communication in the regulation of lipid metabolism. An investigation of the potential druggability of genes in identified loci resulted in five gene targets shown to interact with drugs approved by the Food and Drug Administration, including genes with roles in adipose and brain tissue.Discussion: Genome-wide interaction analysis of educational a
- Published
- 2023
43. Is there a causal role for homocysteine concentration in blood pressure? A Mendelian randomization study
- Author
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Borges, Maria C, Hartwig, Fernando P, Oliveira, Isabel O, and Horta, Bernardo L
- Published
- 2016
- Full Text
- View/download PDF
44. Diminishing benefits of urban living for children and adolescents’ growth and development
- Author
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NCD Risk Factor Collaboration (NCD-RisC), [missing], Mishra, Anu, Zhou, Bin, Rodriguez-Martinez, Andrea, Bixby, Honor, Singleton, Rosie K., Carrillo-Larco, Rodrigo M., Sheffer, Kate E., Paciorek, Christopher J., Bennett, James E., Lhoste, Victor, Iurilli, Maria L. C., Di Cesare, Mariachiara, Bentham, James, Phelps, Nowell H., Sophiea, Marisa K., Stevens, Gretchen A., Danaei, Goodarz, Cowan, Melanie J., Savin, Stefan, Riley, Leanne M., Gregg, Edward W., Aekplakorn, Wichai, Ahmad, Noor Ani, Baker, Jennifer L., Chirita-Emandi, Adela, Farzadfar, Farshad, Fink, Günther, Heinen, Mirjam, Ikeda, Nayu, Kengne, Andre P., Khang, Young-Ho, Laatikainen, Tiina, Laxmaiah, Avula, Ma, Jun, Monroy-Valle, Michele, Mridha, Malay K., Padez, Cristina P., Reynolds, Andrew, Sorić, Maroje, Starc, Gregor, Wirth, James P., Abarca-Gómez, Leandra, Abdeen, Ziad A., Abdrakhmanova, Shynar, Ghaffar, Suhaila Abdul, Abdul Rahim, Hanan F., Abdurrahmonova, Zulfiya, Abu-Rmeileh, Niveen M., Garba, Jamila Abubakar, Acosta-Cazares, Benjamin, Adam, Ishag, Adamczyk, Marzena, Adams, Robert J., Adu-Afarwuah, Seth, Afsana, Kaosar, Afzal, Shoaib, Agbor, Valirie N., Agdeppa, Imelda A., Aghazadeh-Attari, Javad, Aguenaou, Hassan, Aguilar-Salinas, Carlos A., Agyemang, Charles, Ahmad, Mohamad Hasnan, Ahmadi, Ali, Ahmadi, Naser, Ahmadi, Nastaran, Ahmed, Imran, Ahmed, Soheir H., Ahrens, Wolfgang, Aitmurzaeva, Gulmira, Ajlouni, Kamel, Al-Hazzaa, Hazzaa M., Al-Lahou, Badreya, Al-Raddadi, Rajaa, Al Hourani, Huda M., Al Qaoud, Nawal M., Alarouj, Monira, AlBuhairan, Fadia, AlDhukair, Shahla, Aldwairji, Maryam A., Alexius, Sylvia, Ali, Mohamed M., Alkandari, Abdullah, Alkerwi, Ala’a, Alkhatib, Buthaina M., Allin, Kristine, Alvarez-Pedrerol, Mar, Aly, Eman, Amarapurkar, Deepak N., Etxezarreta, Pilar Amiano, Amoah, John, Amougou, Norbert, Amouyel, Philippe, Andersen, Lars Bo, Anderssen, Sigmund A., Androutsos, Odysseas, Ängquist, Lars, Anjana, Ranjit Mohan, Ansari-Moghaddam, Alireza, Anufrieva, Elena, Aounallah-Skhiri, Hajer, Araújo, Joana, Ariansen, Inger, Aris, Tahir, Arku, Raphael E., Arlappa, Nimmathota, Aryal, Krishna K., Aseffa, Nega, Aspelund, Thor, Assah, Felix K., Assembekov, Batyrbek, Assunção, Maria Cecília F., Aung, May Soe, Auvinen, Juha, Avdičová, Mária, Avi, Shina, Azevedo, Ana, Azimi-Nezhad, Mohsen, Azizi, Fereidoun, Azmin, Mehrdad, Babu, Bontha V., Jørgensen, Maja Bæksgaard, Baharudin, Azli, Bahijri, Suhad, Bakacs, Marta, Balakrishna, Nagalla, Balanova, Yulia, Bamoshmoosh, Mohamed, Banach, Maciej, Banegas, José R., Baran, Joanna, Baran, Rafał, Barbagallo, Carlo M., Filho, Valter Barbosa, Barceló, Alberto, Baretić, Maja, Barkat, Amina, Barnoya, Joaquin, Barrera, Lena, Barreto, Marta, Barros, Aluisio J. 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M., Chinnock, Anne, Chiolero, Arnaud, Chiou, Shu-Ti, Chirlaque, María-Dolores, Cho, Belong, Christensen, Kaare, Christofaro, Diego G., Chudek, Jerzy, Cifkova, Renata, Cilia, Michelle, Cinteza, Eliza, Cirillo, Massimo, Claessens, Frank, Clarke, Janine, Clays, Els, Cohen, Emmanuel, Compañ-Gabucio, Laura-María, Concin, Hans, Confortin, Susana C., Cooper, Cyrus, Coppinger, Tara C., Corpeleijn, Eva, Cortés, Lilia Yadira, Costanzo, Simona, Cottel, Dominique, Cowell, Chris, Craig, Cora L., Crampin, Amelia C., Cross, Amanda J., Crujeiras, Ana B., Cruz, Juan J., Csányi, Tamás, Csilla, Semánová, Cucu, Alexandra M., Cui, Liufu, Cureau, Felipe V., Cuschieri, Sarah, Czenczek-Lewandowska, Ewelina, D’Arrigo, Graziella, d’Orsi, Eleonora, Dacica, Liliana, Dallongeville, Jean, Damasceno, Albertino, Damsgaard, Camilla T., Dankner, Rachel, Dantoft, Thomas M., Dasgupta, Parasmani, Dastgiri, Saeed, Dauchet, Luc, Davletov, Kairat, de Assis, Maria Alice Altenburg, De Backer, Gui, De Bacquer, Dirk, De Curtis, Amalia, de Fragas Hinnig, Patrícia, de Gaetano, Giovanni, De Henauw, Stefaan, De Miguel-Etayo, Pilar, de Oliveira, Paula Duarte, De Ridder, David, De Ridder, Karin, de Rooij, Susanne R., De Smedt, Delphine, Deepa, Mohan, Deev, Alexander D., DeGennaro, Vincent, Delisle, Hélène, Delpeuch, Francis, Demarest, Stefaan, Dennison, Elaine, Dereń, Katarzyna, Deschamps, Valérie, Dhimal, Meghnath, Di Castelnuovo, Augusto, Dias-da-Costa, Juvenal Soares, Díaz-Sánchez, María Elena, Diaz, Alejandro, Fernández, Pedro Díaz, Ripollés, María Pilar Díez, Dika, Zivka, Djalalinia, Shirin, Djordjic, Visnja, Do, Ha T. P., Dobson, Annette J., Dominguez, Liria, Donati, Maria Benedetta, Donfrancesco, Chiara, Dong, Guanghui, Dong, Yanhui, Donoso, Silvana P., Döring, Angela, Dorobantu, Maria, Dorosty, Ahmad Reza, Doua, Kouamelan, Dragano, Nico, Drygas, Wojciech, Duan, Jia Li, Duante, Charmaine A., Duboz, Priscilla, Duleva, Vesselka L., Dulskiene, Virginija, Dumith, Samuel C., Dushpanova, Anar, Dyussupova, Azhar, Dzerve, Vilnis, Dziankowska-Zaborszczyk, Elzbieta, Echeverría, Guadalupe, Eddie, Ricky, Eftekhar, Ebrahim, Egbagbe, Eruke E., Eggertsen, Robert, Eghtesad, Sareh, Eiben, Gabriele, Ekelund, Ulf, El-Khateeb, Mohammad, El Ammari, Laila, El Ati, Jalila, Eldemire-Shearer, Denise, Eliasen, Marie, Elliott, Paul, Endevelt, Ronit, Engle-Stone, Reina, Erasmus, Rajiv T., Erbel, Raimund, Erem, Cihangir, Ergor, Gul, Eriksen, Louise, Eriksson, Johan G., Escobedo-de la Peña, Jorge, Eslami, Saeid, Esmaeili, Ali, Evans, Alun, Faeh, David, Fakhradiyev, Ildar, Fakhretdinova, Albina A., Fall, Caroline H., Faramarzi, Elnaz, Farjam, Mojtaba, Sant’Angelo, Victoria Farrugia, Fattahi, Mohammad Reza, Fawwad, Asher, Fawzi, Wafaie W., Feigl, Edit, Felix-Redondo, Francisco J., Ferguson, Trevor S., Fernandes, Romulo A., Fernández-Bergés, Daniel, Ferrante, Daniel, Ferrao, Thomas, Ferrari, Gerson, Ferrari, Marika, Ferrario, Marco M., Ferreccio, Catterina, Ferreira, Haroldo S., Ferrer, Eldridge, Ferrieres, Jean, Figueiró, Thamara Hubler, Fijalkowska, Anna, Fisberg, Mauro, Fischer, Krista, Foo, Leng Huat, Forsner, Maria, Fouad, Heba M., Francis, Damian K., do Carmo Franco, Maria, Fras, Zlatko, Frontera, Guillermo, Fuchs, Flavio D., Fuchs, Sandra C., Fujiati, Isti I., Fujita, Yuki, Fumihiko, Matsuda, Furdela, Viktoriya, Furusawa, Takuro, Gaciong, Zbigniew, Gafencu, Mihai, Cuesta, Manuel Galán, Galbarczyk, Andrzej, Galenkamp, Henrike, Galeone, Daniela, Galfo, Myriam, Galvano, Fabio, Gao, Jingli, Gao, Pei, Garcia-de-la-Hera, Manoli, Mérida, María José García, Solano, Marta García, Gareta, Dickman, Garnett, Sarah P., Gaspoz, Jean-Michel, Gasull, Magda, Gaya, Adroaldo Cesar Araujo, Gaya, Anelise Reis, Gazzinelli, Andrea, Gehring, Ulrike, Geiger, Harald, Geleijnse, Johanna M., George, Ronnie, Ghaderi, Ebrahim, Ghanbari, Ali, Ghasemi, Erfan, Gheorghe-Fronea, Oana-Florentina, Gialluisi, Alessandro, Giampaoli, Simona, Gianfagna, Francesco, Gieger, Christian, Gill, Tiffany K., Giovannelli, Jonathan, Gironella, Glen, Giwercman, Aleksander, Gkiouras, Konstantinos, Glushkova, Natalya, Gluškova, Natalja, Godara, Ramesh, Godos, Justyna, Gogen, Sibel, Goldberg, Marcel, Goltzman, David, Gómez, Georgina, Gómez, Jesús Humberto Gómez, Gomez, Luis F., Gómez, Santiago F., Gomula, Aleksandra, da Silva, Bruna Gonçalves Cordeiro, Gonçalves, Helen, Gonçalves, Mauer, González-Alvarez, Ana D., Gonzalez-Chica, David A., González-Gil, Esther M., Gonzalez-Gross, Marcela, González-Leon, Margot, González-Rivas, Juan P., González-Villalpando, Clicerio, González-Villalpando, María-Elena, Gonzalez, Angel R., Gottrand, Frederic, Graça, Antonio Pedro, Graff-Iversen, Sidsel, Grafnetter, Dušan, Grajda, Aneta, Grammatikopoulou, Maria G., Gregor, Ronald D., Gregório, Maria João, Grøholt, Else Karin, Grøntved, Anders, Grosso, Giuseppe, Gruden, Gabriella, Gu, Dongfeng, Guajardo, Viviana, Gualdi-Russo, Emanuela, Guallar-Castillón, Pilar, Gualtieri, Andrea, Gudmundsson, Elias F., Gudnason, Vilmundur, Guerrero, Ramiro, Guessous, Idris, Guimaraes, Andre L., Gulliford, Martin C., Gunnlaugsdottir, Johanna, Gunter, Marc J., Guo, Xiu-Hua, Guo, Yin, Gupta, Prakash C., Gupta, Rajeev, Gureje, Oye, González, Enrique Gutiérrez, Gutierrez, Laura, Gutzwiller, Felix, Gwee, Xinyi, Ha, Seongjun, Hadaegh, Farzad, Hadjigeorgiou, Charalambos A., Haghshenas, Rosa, Hakimi, Hamid, Halkjær, Jytte, Hambleton, Ian R., Hamzeh, Behrooz, Hanekom, Willem A., Hange, Dominique, Hanif, Abu A. 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G., Keramati, Maryam, Kerimkulova, Alina, Kersting, Mathilde, Key, Timothy, Khader, Yousef Saleh, Khaledifar, Arsalan, Khalili, Davood, Khaw, Kay-Tee, Kheiri, Bahareh, Kheradmand, Motahareh, Khosravi, Alireza, Khouw, Ilse M. S. L., Kiechl-Kohlendorfer, Ursula, Kiechl, Sophia J., Kiechl, Stefan, Killewo, Japhet, Kim, Hyeon Chang, Kim, Jeongseon, Kindblom, Jenny M., Kingston, Andrew, Klakk, Heidi, Klimek, Magdalena, Klimont, Jeannette, Klumbiene, Jurate, Knoflach, Michael, Koirala, Bhawesh, Kolle, Elin, Kolsteren, Patrick, König, Jürgen, Korpelainen, Raija, Korrovits, Paul, Korzycka, Magdalena, Kos, Jelena, Koskinen, Seppo, Kouda, Katsuyasu, Kovács, Éva, Kovacs, Viktoria Anna, Kovalskys, Irina, Kowlessur, Sudhir, Koziel, Slawomir, Kratenova, Jana, Kratzer, Wolfgang, Kriaucioniene, Vilma, Kriemler, Susi, Kristensen, Peter Lund, Krizan, Helena, Kroker-Lobos, Maria F., Krokstad, Steinar, Kromhout, Daan, Kruger, Herculina S., Kruger, Ruan, Kryst, Łukasz, Kubinova, Ruzena, Kuciene, Renata, Kujala, Urho M., Kujundzic, Enisa, Kulaga, Zbigniew, Kulimbet, Mukhtar, Kumar, R. Krishna, Kunešová, Marie, Kurjata, Pawel, Kusuma, Yadlapalli S., Kutsenko, Vladimir, Kuulasmaa, Kari, Kyobutungi, Catherine, La, Quang Ngoc, Laamiri, Fatima Zahra, Lachat, Carl, Lackner, Karl J., Laid, Youcef, Lall, Lachmie, Lam, Tai Hing, Jimenez, Maritza Landaeta, Landais, Edwige, Lanska, Vera, Lappas, Georg, Larijani, Bagher, Larissa, Simo Pone, Latt, Tint Swe, Laurenzi, Martino, Lauria, Laura, Lazo-Porras, Maria, Le Coroller, Gwenaëlle, Le Nguyen Bao, Khanh, Le Port, Agnès, Le, Tuyen D., Lee, Jeannette, Lee, Jeonghee, Lee, Paul H., Lehmann, Nils, Lehtimäki, Terho, Lemogoum, Daniel, Leskošek, Branimir, Leszczak, Justyna, Leth-Møller, Katja B., Leung, Gabriel M., Levitt, Naomi S., Li, Yanping, Liivak, Merike, Lilly, Christa L., Lim, Charlie, Lim, Wei-Yen, Lima-Costa, M. Fernanda, Lin, Hsien-Ho, Lin, Xu, Lin, Yi-Ting, Lind, Lars, Lingam, Vijaya, Linkohr, Birgit, Linneberg, Allan, Lissner, Lauren, Litwin, Mieczyslaw, Liu, Jing, Liu, Lijuan, Lo, Wei-Cheng, Loit, Helle-Mai, Long, Khuong Quynh, Abril, Guadalupe Longo, Lopes, Luis, Lopes, Marcus V. V., Lopes, Oscar, Lopez-Garcia, Esther, Lopez, Tania, Lotufo, Paulo A., Lozano, José Eugenio, Lukrafka, Janice L., Luksiene, Dalia, Lundqvist, Annamari, Lunet, Nuno, Lunogelo, Charles, Lustigová, Michala, Łuszczki, Edyta, M’Buyamba-Kabangu, Jean-René, Ma, Guansheng, Ma, Xu, Machado-Coelho, George L. L., Machado-Rodrigues, Aristides M., Macia, Enguerran, Macieira, Luisa M., Madar, Ahmed A., Madsen, Anja L., Maestre, Gladys E., Maggi, Stefania, Magliano, Dianna J., Magnacca, Sara, Magriplis, Emmanuella, Mahasampath, Gowri, Maire, Bernard, Majer, Marjeta, Makdisse, Marcia, Mäki, Päivi, Malekzadeh, Fatemeh, Malekzadeh, Reza, Malhotra, Rahul, Rao, Kodavanti Mallikharjuna, Malyutina, Sofia K., Maniego, Lynell V., Manios, Yannis, Manix, Masimango Imani, Mann, Jim I., Mansour-Ghanaei, Fariborz, Manyanga, Taru, Manzato, Enzo, Marcil, Anie, Margozzini, Paula, Mariño, Joany, Markaki, Anastasia, Markey, Oonagh, Ioannidou, Eliza Markidou, Marques-Vidal, Pedro, Marques, Larissa Pruner, Marrugat, Jaume, Martin-Prevel, Yves, Martin, Rosemarie, Martorell, Reynaldo, Martos, Eva, Maruszczak, Katharina, Marventano, Stefano, Masala, Giovanna, Mascarenhas, Luis P., Masoodi, Shariq R., Mathiesen, Ellisiv B., Mathur, Prashant, Matijasevich, Alicia, Matłosz, Piotr, Matsha, Tandi E., Matsudo, Victor, Mavrogianni, Christina, Mazur, Artur, Mbanya, Jean Claude N., McFarlane, Shelly R., McGarvey, Stephen T., McKee, Martin, McLachlan, Stela, McLean, Rachael M., McLean, Scott B., McNairy, Margaret L., McNulty, Breige A., Benchekor, Sounnia Mediene, Medzioniene, Jurate, Mehdipour, Parinaz, Mehlig, Kirsten, Mehrparvar, Amir Houshang, Meirhaeghe, Aline, Meisfjord, Jørgen, Meisinger, Christa, Melgarejo, Jesus D., Melkumova, Marina, Mello, João, Méndez, Fabián, Mendivil, Carlos O., Menezes, Ana Maria B., Menon, Geetha R., Mensink, Gert B. 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C., Nabipour, Iraj, Naderimagham, Shohreh, Nagel, Gabriele, Najafi, Farid, Nakamura, Harunobu, Nalecz, Hanna, Námešná, Jana, Nang, Ei Ei K., Nangia, Vinay B., Nankap, Martin, Narake, Sameer, Nardone, Paola, Naseri, Take, Nauck, Matthias, Neal, William A., Nejatizadeh, Azim, Nekkantti, Chandini, Nelis, Keiu, Nenko, Ilona, Neovius, Martin, Nervi, Flavio, Ng, Tze Pin, Nguyen, Chung T., Nguyen, Nguyen D., Nguyen, Quang Ngoc, Ni, Michael Y., Nicolescu, Rodica, Nie, Peng, Nieto-Martínez, Ramfis E., Nikitin, Yury P., Ning, Guang, Ninomiya, Toshiharu, Nishi, Nobuo, Nishtar, Sania, Noale, Marianna, Noboa, Oscar A., Nogueira, Helena, Nordendahl, Maria, Nordestgaard, Børge G., Noto, Davide, Nowak-Szczepanska, Natalia, Nsour, Mohannad Al, Nuhoğlu, Irfan, Nunes, Baltazar, Nurk, Eha, Nuwaha, Fred, Nyirenda, Moffat, O’Neill, Terence W., O’Reilly, Dermot, Obreja, Galina, Ochimana, Caleb, Ochoa-Avilés, Angélica M., Oda, Eiji, Odili, Augustine N., Oh, Kyungwon, Ohara, Kumiko, Ohlsson, Claes, Ohtsuka, Ryutaro, Olafsson, Örn, Olinto, Maria Teresa A., Oliveira, Isabel O., Omar, Mohd Azahadi, Omar, Saeed M., Onat, Altan, Ong, Sok King, Onland-Moret, N. Charlotte, Ono, Lariane M., Ordunez, Pedro, Ornelas, Rui, Ortiz, Ana P., Ortiz, Pedro J., Osler, Merete, Osmond, Clive, Ostojic, Sergej M., Ostovar, Afshin, Otero, Johanna A., Overvad, Kim, Owusu-Dabo, Ellis, Paccaud, Fred Michel, Pagkalos, Ioannis, Pahomova, Elena, de Paiva, Karina Mary, Pająk, Andrzej, Palloni, Alberto, Palmieri, Luigi, Pan, Wen-Harn, Panda-Jonas, Songhomitra, Pandey, Arvind, Panza, Francesco, Paoli, Mariela, Papadopoulou, Sousana K., Papandreou, Dimitrios, Pareja, Rossina G., Park, Soon-Woo, Park, Suyeon, Parnell, Winsome R., Parsaeian, Mahboubeh, Pascanu, Ionela M., Pasquet, Patrick, Patel, Nikhil D., Pattussi, Marcos, Pavlyshyn, Halyna, Pechlaner, Raimund, Pećin, Ivan, Pednekar, Mangesh S., Pedro, João M., Peer, Nasheeta, Peixoto, Sergio Viana, Peltonen, Markku, Pereira, Alexandre C., Peres, Marco A., Pérez, Cynthia M., Peterkova, Valentina, Peters, Annette, Petersmann, Astrid, Petkeviciene, Janina, Petrauskiene, Ausra, Kovtun, Olga Petrovna, Pettenuzzo, Emanuela, Peykari, Niloofar, Pfeiffer, Norbert, Phall, Modou Cheyassin, Pham, Son Thai, Pichardo, Rafael N., Pierannunzio, Daniela, Pigeot, Iris, Pikhart, Hynek, Pilav, Aida, Pilotto, Lorenza, Pistelli, Francesco, Pitakaka, Freda, Piwonska, Aleksandra, Pizarro, Andreia N., Plans-Rubió, Pedro, Platonova, Alina G., Poh, Bee Koon, Pohlabeln, Hermann, Polka, Nadija S., Pop, Raluca M., Popovic, Stevo R., Porta, Miquel, Posch, Georg, Poudyal, Anil, Poulimeneas, Dimitrios, Pouraram, Hamed, Pourfarzi, Farhad, Pourshams, Akram, Poustchi, Hossein, Pradeepa, Rajendra, Price, Alison J., Price, Jacqueline F., Prista, Antonio, Providencia, Rui, Puder, Jardena J., Pudule, Iveta, Puiu, Maria, Punab, Margus, Qadir, Muhammed S., Qasrawi, Radwan F., Qorbani, Mostafa, Quintana, Hedley K., Quiroga-Padilla, Pedro J., Bao, Tran Quoc, Rach, Stefan, Radic, Ivana, Radisauskas, Ricardas, Rahimikazerooni, Salar, Rahman, Mahfuzar, Rahman, Mahmudur, Raitakari, Olli, Raj, Manu, Rajabov, Tamerlan, Rakhmatulloev, Sherali, Rakovac, Ivo, Rao, Sudha Ramachandra, Ramachandran, Ambady, Ramadan, Otim P. C., Ramires, Virgílio V., Ramke, Jacqueline, Ramos, Elisabete, Ramos, Rafel, Rampal, Lekhraj, Rampal, Sanjay, Rangelova, Lalka S., Rarra, Vayia, Rascon-Pacheco, Ramon A., Rech, Cassiano Ricardo, Redon, Josep, Reganit, Paul Ferdinand M., Regecová, Valéria, Renner, Jane D. P., Repasy, Judit A., Reuter, Cézane P., Revilla, Luis, Rezaianzadeh, Abbas, Rho, Yeunsook, Ribas-Barba, Lourdes, Ribeiro, Robespierre, Riboli, Elio, Richter, Adrian, Rigo, Fernando, Rigotti, Attilio, Rinaldo, Natascia, Rinke de Wit, Tobias F., Rito, Ana I., Ritti-Dias, Raphael M., Rivera, Juan A., Roa, Reina G., Robinson, Louise, Robitaille, Cynthia, Roccaldo, Romana, Rodrigues, Daniela, Rodríguez-Artalejo, Fernando, del Cristo Rodriguez-Perez, María, Rodríguez-Villamizar, Laura A., Rodríguez, Andrea Y., Roggenbuck, Ulla, Rohloff, Peter, Rohner, Fabian, Rojas-Martinez, Rosalba, Rojroongwasinkul, Nipa, Romaguera, Dora, Romeo, Elisabetta L., Rosario, Rafaela V., Rosengren, Annika, Rouse, Ian, Rouzier, Vanessa, Roy, Joel G. R., Ruano, Maira H., Rubinstein, Adolfo, Rühli, Frank J., Ruidavets, Jean-Bernard, Ruiz-Betancourt, Blanca Sandra, Ruiz-Castell, Maria, Moreno, Emma Ruiz, Rusakova, Iuliia A., Jonsson, Kenisha Russell, Russo, Paola, Rust, Petra, Rutkowski, Marcin, Saamel, Marge, Sabanayagam, Charumathi, Sabbaghi, Hamideh, Sacchini, Elena, Sachdev, Harshpal S., Sadjadi, Alireza, Safarpour, Ali Reza, Safi, Sare, Safiri, Saeid, Saghi, Mohammad Hossien, Saidi, Olfa, Saki, Nader, Šalaj, Sanja, Salanave, Benoit, Martinez, Eduardo Salazar, Saleva, Calogero, Salmerón, Diego, Salomaa, Veikko, Salonen, Jukka T., Salvetti, Massimo, Samoutian, Margarita, Sánchez-Abanto, Jose, Rodríguez, Inés Sánchez, Sandjaja, [missing], Sans, Susana, Marina, Loreto Santa, Santacruz, Ethel, Santos, Diana A., Santos, Ina S., Santos, Lèlita C., Santos, Maria Paula, Santos, Osvaldo, Santos, Rute, Santos, Tamara R., Saramies, Jouko L., Sardinha, Luis B., Sarrafzadegan, Nizal, Sathish, Thirunavukkarasu, Saum, Kai-Uwe, Savva, Savvas, Savy, Mathilde, Sawada, Norie, Sbaraini, Mariana, Scazufca, Marcia, Schaan, Beatriz D., Rosario, Angelika Schaffrath, Schargrodsky, Herman, Schienkiewitz, Anja, Schindler, Karin, Schipf, Sabine, Schmidt, Carsten O., Schmidt, Ida Maria, Schneider, Andrea, Schnohr, Peter, Schöttker, Ben, Schramm, Sara, Schramm, Stine, Schröder, Helmut, Schultsz, Constance, Schulze, Matthias B., Schutte, Aletta E., Sebert, Sylvain, Sedaghattalab, Moslem, Selamat, Rusidah, Sember, Vedrana, Sen, Abhijit, Senbanjo, Idowu O., Sepanlou, Sadaf G., Sequera, Guillermo, Serra-Majem, Luis, Servais, Jennifer, Ševčíková, Ľudmila, Shalnova, Svetlana, Shamah-Levy, Teresa, Shamshirgaran, Seyed Morteza, Shanthirani, Coimbatore Subramaniam, Sharafkhah, Maryam, Sharma, Sanjib K., Shaw, Jonathan E., Shayanrad, Amaneh, Shayesteh, Ali Akbar, Shengelia, Lela, Shi, Zumin, Shibuya, Kenji, Shimizu-Furusawa, Hana, Shimony, Tal, Shiri, Rahman, Shrestha, Namuna, Si-Ramlee, Khairil, Siani, Alfonso, Siantar, Rosalynn, Sibai, Abla M., Sidossis, Labros S., Silitrari, Natalia, Silva, Antonio M., de Moura Silva, Caroline Ramos, Silva, Diego Augusto Santos, Silva, Kelly S., Sim, Xueling, Simon, Mary, Simons, Judith, Simons, Leon A., Sjöberg, Agneta, Sjöström, Michael, Skoblina, Natalia A., Skodje, Gry, Slazhnyova, Tatyana, Slowikowska-Hilczer, Jolanta, Slusarczyk, Przemysław, Smeeth, Liam, So, Hung-Kwan, Soares, Fernanda Cunha, Sobek, Grzegorz, Sobngwi, Eugène, Sodemann, Morten, Söderberg, Stefan, Soekatri, Moesijanti Y. E., Soemantri, Agustinus, Sofat, Reecha, Solfrizzi, Vincenzo, Somi, Mohammad Hossein, Sonestedt, Emily, Song, Yi, Soofi, Sajid, Sørensen, Thorkild I. A., Sørgjerd, Elin P., Jérome, Charles Sossa, Soto-Rojas, Victoria E., Soumaré, Aïcha, Sousa-Poza, Alfonso, Sovic, Slavica, Sparboe-Nilsen, Bente, Sparrenberger, Karen, Spencer, Phoebe R., Spinelli, Angela, Spiroski, Igor, Staessen, Jan A., Stamm, Hanspeter, Staub, Kaspar, Stavreski, Bill, Steene-Johannessen, Jostein, Stehle, Peter, Stein, Aryeh D., Stergiou, George S., Stessman, Jochanan, Stevanović, Ranko, Stieber, Jutta, Stöckl, Doris, Stokwiszewski, Jakub, Stoyanova, Ekaterina, Stratton, Gareth, Stronks, Karien, Strufaldi, Maria Wany, Sturua, Lela, Suárez-Medina, Ramón, Suka, Machi, Sun, Chien-An, Sun, Liang, Sundström, Johan, Sung, Yn-Tz, Sunyer, Jordi, Suriyawongpaisal, Paibul, Sweis, Nabil William G., Swinburn, Boyd A., Sy, Rody G., Sylva, René Charles, Szklo, Moyses, Szponar, Lucjan, Tabone, Lorraine, Tai, E. Shyong, Tambalis, Konstantinos D., Tammesoo, Mari-Liis, Tamosiunas, Abdonas, Tan, Eng Joo, Tang, Xun, Tanrygulyyeva, Maya, Tanser, Frank, Tao, Yong, Tarawneh, Mohammed Rasoul, Tarp, Jakob, Tarqui-Mamani, Carolina B., Braunerová, Radka Taxová, Taylor, Anne, Taylor, Julie, Tchibindat, Félicité, Te Velde, Saskia, Tebar, William R., Tell, Grethe S., Tello, Tania, Tham, Yih Chung, Thankappan, K. R., Theobald, Holger, Theodoridis, Xenophon, Thomas, Nihal, Thorand, Barbara, Thuesen, Betina H., Tichá, Ľubica, Timmermans, Erik J., Tjandrarini, Dwi H., Tjonneland, Anne, Tolonen, Hanna K., Tolstrup, Janne S., Topbas, Murat, Topór-Mądry, Roman, Torheim, Liv Elin, Tormo, María José, Tornaritis, Michael J., Torrent, Maties, Torres-Collado, Laura, Toselli, Stefania, Touloumi, Giota, Traissac, Pierre, Tran, Thi Tuyet-Hanh, Tremblay, Mark S., Triantafyllou, Areti, Trichopoulos, Dimitrios, Trichopoulou, Antonia, Trinh, Oanh T. 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Developing world ,Public health ,Multidisciplinary ,Science General ,Paediatric research ,Nutrition - Abstract
Optimal growth and development in childhood and adolescence is crucial for lifelong health and well-being1–6. Here we used data from 2,325 population-based studies, with measurements of height and weight from 71 million participants, to report the height and body-mass index (BMI) of children and adolescents aged 5–19 years on the basis of rural and urban place of residence in 200 countries and territories from 1990 to 2020. In 1990, children and adolescents residing in cities were taller than their rural counterparts in all but a few high-income countries. By 2020, the urban height advantage became smaller in most countries, and in many high-income western countries it reversed into a small urban-based disadvantage. The exception was for boys in most countries in sub-Saharan Africa and in some countries in Oceania, south Asia and the region of central Asia, Middle East and north Africa. In these countries, successive cohorts of boys from rural places either did not gain height or possibly became shorter, and hence fell further behind their urban peers. The difference between the age-standardized mean BMI of children in urban and rural areas was
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- 2023
45. Breastfeeding and maternal cardiovascular risk factors: 1982 Pelotas Birth Cohort
- Author
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Lima, Natália P., Bassani, Diego G., Magalhães, Elma Izze S., Barros, Fernando C., and Horta, Bernardo L.
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- 2019
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46. Multi-ancestry study of blood lipid levels identifies four loci interacting with physical activity
- Author
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Kilpeläinen, Tuomas O., Bentley, Amy R., Noordam, Raymond, Sung, Yun Ju, Schwander, Karen, Winkler, Thomas W., Jakupović, Hermina, Chasman, Daniel I., Manning, Alisa, Ntalla, Ioanna, Aschard, Hugues, Brown, Michael R., de las Fuentes, Lisa, Franceschini, Nora, Guo, Xiuqing, Vojinovic, Dina, Aslibekyan, Stella, Feitosa, Mary F., Kho, Minjung, Musani, Solomon K., Richard, Melissa, Wang, Heming, Wang, Zhe, Bartz, Traci M., Bielak, Lawrence F., Campbell, Archie, Dorajoo, Rajkumar, Fisher, Virginia, Hartwig, Fernando P., Horimoto, Andrea R. V. R., Li, Changwei, Lohman, Kurt K., Marten, Jonathan, Sim, Xueling, Smith, Albert V., Tajuddin, Salman M., Alver, Maris, Amini, Marzyeh, Boissel, Mathilde, Chai, Jin Fang, Chen, Xu, Divers, Jasmin, Evangelou, Evangelos, Gao, Chuan, Graff, Mariaelisa, Harris, Sarah E., He, Meian, Hsu, Fang-Chi, Jackson, Anne U., Zhao, Jing Hua, Kraja, Aldi T., Kühnel, Brigitte, Laguzzi, Federica, Lyytikäinen, Leo-Pekka, Nolte, Ilja M., Rauramaa, Rainer, Riaz, Muhammad, Robino, Antonietta, Rueedi, Rico, Stringham, Heather M., Takeuchi, Fumihiko, van der Most, Peter J., Varga, Tibor V., Verweij, Niek, Ware, Erin B., Wen, Wanqing, Li, Xiaoyin, Yanek, Lisa R., Amin, Najaf, Arnett, Donna K., Boerwinkle, Eric, Brumat, Marco, Cade, Brian, Canouil, Mickaël, Chen, Yii-Der Ida, Concas, Maria Pina, Connell, John, de Mutsert, Renée, de Silva, H. Janaka, de Vries, Paul S., Demirkan, Ayşe, Ding, Jingzhong, Eaton, Charles B., Faul, Jessica D., Friedlander, Yechiel, Gabriel, Kelley P., Ghanbari, Mohsen, Giulianini, Franco, Gu, Chi Charles, Gu, Dongfeng, Harris, Tamara B., He, Jiang, Heikkinen, Sami, Heng, Chew-Kiat, Hunt, Steven C., Ikram, M. Arfan, Jonas, Jost B., Koh, Woon-Puay, Komulainen, Pirjo, Krieger, Jose E., Kritchevsky, Stephen B., Kutalik, Zoltán, Kuusisto, Johanna, Langefeld, Carl D., Langenberg, Claudia, Launer, Lenore J., Leander, Karin, Lemaitre, Rozenn N., Lewis, Cora E., Liang, Jingjing, Lifelines Cohort Study, Liu, Jianjun, Mägi, Reedik, Manichaikul, Ani, Meitinger, Thomas, Metspalu, Andres, Milaneschi, Yuri, Mohlke, Karen L., Mosley, Jr., Thomas H., Murray, Alison D., Nalls, Mike A., Nang, Ei-Ei Khaing, Nelson, Christopher P., Nona, Sotoodehnia, Norris, Jill M., Nwuba, Chiamaka Vivian, O’Connell, Jeff, Palmer, Nicholette D., Papanicolau, George J., Pazoki, Raha, Pedersen, Nancy L., Peters, Annette, Peyser, Patricia A., Polasek, Ozren, Porteous, David J., Poveda, Alaitz, Raitakari, Olli T., Rich, Stephen S., Risch, Neil, Robinson, Jennifer G., Rose, Lynda M., Rudan, Igor, Schreiner, Pamela J., Scott, Robert A., Sidney, Stephen S., Sims, Mario, Smith, Jennifer A., Snieder, Harold, Sofer, Tamar, Starr, John M., Sternfeld, Barbara, Strauch, Konstantin, Tang, Hua, Taylor, Kent D., Tsai, Michael Y., Tuomilehto, Jaakko, Uitterlinden, André G., van der Ende, M. Yldau, van Heemst, Diana, Voortman, Trudy, Waldenberger, Melanie, Wennberg, Patrik, Wilson, Gregory, Xiang, Yong-Bing, Yao, Jie, Yu, Caizheng, Yuan, Jian-Min, Zhao, Wei, Zonderman, Alan B., Becker, Diane M., Boehnke, Michael, Bowden, Donald W., de Faire, Ulf, Deary, Ian J., Elliott, Paul, Esko, Tõnu, Freedman, Barry I., Froguel, Philippe, Gasparini, Paolo, Gieger, Christian, Kato, Norihiro, Laakso, Markku, Lakka, Timo A., Lehtimäki, Terho, Magnusson, Patrik K. E., Oldehinkel, Albertine J., Penninx, Brenda W. J. H., Samani, Nilesh J., Shu, Xiao-Ou, van der Harst, Pim, Van Vliet-Ostaptchouk, Jana V., Vollenweider, Peter, Wagenknecht, Lynne E., Wang, Ya X., Wareham, Nicholas J., Weir, David R., Wu, Tangchun, Zheng, Wei, Zhu, Xiaofeng, Evans, Michele K., Franks, Paul W., Gudnason, Vilmundur, Hayward, Caroline, Horta, Bernardo L., Kelly, Tanika N., Liu, Yongmei, North, Kari E., Pereira, Alexandre C., Ridker, Paul M., Tai, E. Shyong, van Dam, Rob M., Fox, Ervin R., Kardia, Sharon L. R., Liu, Ching-Ti, Mook-Kanamori, Dennis O., Province, Michael A., Redline, Susan, van Duijn, Cornelia M., Rotter, Jerome I., Kooperberg, Charles B., Gauderman, W. James, Psaty, Bruce M., Rice, Kenneth, Munroe, Patricia B., Fornage, Myriam, Cupples, L. Adrienne, Rotimi, Charles N., Morrison, Alanna C., Rao, Dabeeru C., and Loos, Ruth J. F.
- Published
- 2019
- Full Text
- View/download PDF
47. Early-life stature, preschool cognitive development, schooling attainment, and cognitive functioning in adulthood: a prospective study in four birth cohorts
- Author
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Stein, Aryeh D, primary, Adair, Linda S, additional, Donati, Georgina, additional, Wray, Charlotte, additional, Richter, Linda M, additional, Norris, Shane A, additional, Stein, Alan, additional, Martorell, Reynaldo, additional, Ramirez-Zea, Manuel, additional, Menezes, Ana M B, additional, Murray, Joseph, additional, Victora, Cesar, additional, Lee, Nanette, additional, Bas, Isabelita, additional, Kowalski, Alysse, additional, DiGirolamo, Ann, additional, Scerif, Gaia, additional, Mpondo, Feziwe, additional, Belleza, Delia, additional, Nyati, Lukhanyo, additional, Osmond, Clive, additional, Borja, Judith Rafaelita, additional, Carba, Delia, additional, Perez, Tita Lorna, additional, Bechavda, Sonny Agustin, additional, Kroker-Lobos, Maria F, additional, Varghese, Jithin S, additional, Barros, Fernando C, additional, Hartwig, Fernando P, additional, Horta, Bernardo L, additional, and Wehrmeister, Fernando C, additional
- Published
- 2023
- Full Text
- View/download PDF
48. Condições de nascimento e transtorno do déficit de atenção com hiperatividade (TDAH) em adultos nas coortes de nascimento de Pelotas, Rio Grande do Sul, Brasil, de 1982 e 1993
- Author
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Farias, Cid Pinheiro, primary, Soares, Pedro San Martin, additional, Barros, Fernando C., additional, Menezes, Ana Maria Baptista, additional, Gonçalves, Helen, additional, Wehrmeister, Fernando César, additional, Pinheiro, Ricardo Tavares, additional, Quevedo, Luciana de Avila, additional, and Horta, Bernardo L., additional
- Published
- 2023
- Full Text
- View/download PDF
49. Gestational age and newborn size according to parental social mobility : an intergenerational cohort study
- Author
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Gigante, Denise P, Horta, Bernardo L, Matijasevich, Alicia, de Mola, Christian Loret, Barros, Aluisio J D, Santos, Ina S, Barros, Fernando C, and Victora, Cesar G
- Published
- 2015
50. Origin and dynamics of admixture in Brazilians and its effect on the pattern of deleterious mutations
- Author
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The Brazilian EPIGEN Project Consortium, Kehdy, Fernanda S. G., Gouveia, Mateus H., Machado, Moara, Magalhães, Wagner C. S., Horimoto, Andrea R., Horta, Bernardo L., Moreira, Rennan G., Leal, Thiago P., Scliar, Marilia O., Soares-Souza, Giordano B., Rodrigues-Soares, Fernanda, Araújo, Gilderlanio S., Zamudio, Roxana, Anna, Hanaisa P. Sant, Santos, Hadassa C., Duarte, Nubia E., Fiaccone, Rosemeire L., Figueiredo, Camila A., Silva, Thiago M., Costa, Gustavo N. O., Beleza, Sandra, Berg, Douglas E., Cabrera, Lilia, Debortoli, Guilherme, Duarte, Denise, Ghirotto, Silvia, Gilman, Robert H., Gonçalves, Vanessa F., Marrero, Andrea R., Muniz, Yara C., Weissensteiner, Hansi, Yeager, Meredith, Rodrigues, Laura C., Barreto, Mauricio L., Lima-Costa, M. Fernanda, Pereira, Alexandre C., Rodrigues, Maíra R., and Tarazona-Santos, Eduardo
- Published
- 2015
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