28 results on '"Horst J. Jaeger"'
Search Results
2. CT-guided puncture for direct MR-arthrography of the shoulder: Description of possible techniques
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Cozub-Poetica C, Elke Hauth, Horst J. Jaeger, Meinrad Beer, and Wieja G
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Mr arthrography ,business.industry ,glenohumeral joint ,CT-guided approach ,technique ,radiation dose ,direct MR-arthrography ,lcsh:R ,lcsh:Medicine ,Medicine ,Nuclear medicine ,business ,human activities - Abstract
The following report describes the possible techniques of CT-guided puncture for direct magnetic resonance (MR) arthrography of the shoulder. CT-guided puncture can be regarded as an alternative technique to fluoroscopic- or ultrasound-guided puncture for MR-arthrography of the shoulder with high efficiency, low dose and extremely low complication rate.
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- 2016
3. Diagnostic value of semi-quantitative and quantitative analysis of functional parameters in multiparametric MRI of the prostate
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Horst J. Jaeger, Horst Hohmuth, Daniela Halbritter, Elke Hauth, and Meinrad Beer
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In vivo magnetic resonance spectroscopy ,Male ,030218 nuclear medicine & medical imaging ,03 medical and health sciences ,Prostate cancer ,0302 clinical medicine ,Prostate ,Predictive Value of Tests ,medicine ,Effective diffusion coefficient ,Humans ,Radiology, Nuclear Medicine and imaging ,Aged ,Retrospective Studies ,Aged, 80 and over ,medicine.diagnostic_test ,Full Paper ,business.industry ,Ultrasound ,Prostatic Neoplasms ,Magnetic resonance imaging ,General Medicine ,Middle Aged ,medicine.disease ,Magnetic Resonance Imaging ,medicine.anatomical_structure ,Evaluation Studies as Topic ,030220 oncology & carcinogenesis ,Predictive value of tests ,business ,Nuclear medicine ,Quantitative analysis (chemistry) - Abstract
To determine the diagnostic value of semi-quantitative and quantitative parameters of three functional techniques in multiparametric (mp)-MRI of the prostate.Mp-MRI was performed in 110 patients with suspicion of prostate cancer (PCA) before transrectal ultrasound (TRUS)-guided core biopsy. Peak-enhancement, initial and post-initial enhancement, initial area under gadolinium curve, Ktrans (forward rate constant), Kep (efflux rate constant), Ve (extracellular volume), ADC (apparent diffusion coefficient) and MR spectroscopy ratio were obtained for malignant and benign lesions. For iAUGC, Ktrans, Kep and Ve we evaluated median, mean and the difference (Diff) between mean and median. For ADC we evaluated mean, median, Diff between mean and median, and min. In addition, we evaluated these parameters in dependence of Gleason score in PCA. Receiver operating characteristic analysis and area under curve (AUC) were determined.ADC min and Kep Diff were the best predictors of malignancy in all lesions (AUC: 0.765). ADC min was the best predictor of malignancy for lesions in peripheral zone (PZ) (AUC: 0.7506) and Kep Diff was the best predictor of malignancy for lesions in transitional zone (AUC: 0.7514). Peak enhancement was the best parameter in differentiation of low-grade PCA with Gleason score 6 from high-grade PCA with Gleason score ≥ 7 (AUC: 0.7692).ADC min can differentiate PCA from benign prostate lesions in PZ. Kep Diff could possibly improve prostate cancer detection in. Peak enhancement might be able to differentiate low grade from high-grade PCA. Semi-quantitative and quantitative parameters may be useful for the functional techniques in mp-MRI. Advances in knowledge: ADC min can differentiate PCA from benign prostate lesions in PZ. Peak enhancement might be able to differentiate low grade from high-grade PCA.
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- 2017
4. MR imaging for detection of trampoline injuries in children
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Meinrad Beer, Elke Hauth, Horst J. Jaeger, and P. Luckey
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Male ,medicine.medical_specialty ,Adolescent ,Radiography ,Poison control ,03 medical and health sciences ,Trampoline ,0302 clinical medicine ,030225 pediatrics ,Injury prevention ,medicine ,Humans ,Pediatrics, Perinatology, and Child Health ,030212 general & internal medicine ,Child ,Retrospective Studies ,Injuries ,business.industry ,medicine.disease ,Sacrum ,Magnetic Resonance Imaging ,Surgery ,Fracture ,medicine.anatomical_structure ,Child, Preschool ,Radiological weapon ,Pediatrics, Perinatology and Child Health ,Soft tissue injury ,Recreation ,Wounds and Injuries ,Female ,Ankle ,business ,Research Article ,MR imaging - Abstract
Background The recreational use of trampolines is an increasingly popular activity among children and adolescents. Several studies reported about radiological findings in trampoline related injuries in children. The following publication presents our experience with MRI for detection of trampoline injuries in children. Methods 20 children (mean 9.2 years, range: 4–15 years) who had undergone an MRI study for detection of suspected trampoline injuries within one year were included. 9/20 (45%) children had a radiograph as the first imaging modality in conjunction with primary care. In 11/20 (55%) children MR imaging was performed as the first modality. MR imaging was performed on two 1.5 T scanners with 60 and 70 cm bore design respectively without sedation. In 9/20 (45%) children the injury mechanism was a collision with another child. 7/20 (35%) children experienced leg pain several hours to one day after using the trampoline without acute accident and 4/20 (20%) children described a fall from the trampoline to the ground. Results All plain radiographs were performed in facilities outside the study centre and all were classified as having no pathological findings. In contrast, MR imaging detected injuries in 15/20 (75%) children. Lower extremity injuries were the most common findings, observed in 12/15 (80%) children. Amongst these, injuries of the ankle and foot were diagnosed in 7/15 (47%) patients. Fractures of the proximal tibial metaphysis were observed in 3/15 children. One child had developed a thoracic vertebral fracture. The two remaining children experienced injuries to the sacrum and a soft tissue injury of the thumb respectively. Seven children described clinical symptoms without an overt accident. Here, fractures of the proximal tibia were observed in 2 children, a hip joint effusion in another 2, and an injury of the ankle and foot in 1 child. There were no associated spinal cord injuries, no fracture dislocations, no vascular injuries and no head and neck injuries. Conclusions In the majority of children referred for MR imaging with pain after trampoline MR imaging detects injuries. These injuries are often not visible on plain radiographs. Therefore we recommend a generous use of MR imaging in these children after initial negative plain radiography.
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- 2017
5. Follow-up MR imaging of PI-RADS 3 and PI-RADS 4 prostate lesions
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Horst J. Jaeger, Horst Hohmuth, Meinrad Beer, and Elke Hauth
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Adult ,Male ,medicine.medical_specialty ,Malignancy ,030218 nuclear medicine & medical imaging ,03 medical and health sciences ,Prostate cancer ,0302 clinical medicine ,Prostate ,Biopsy ,medicine ,Humans ,Radiology, Nuclear Medicine and imaging ,Aged ,Aged, 80 and over ,medicine.diagnostic_test ,business.industry ,Cancer ,Prostatic Neoplasms ,Middle Aged ,medicine.disease ,Mr imaging ,Magnetic Resonance Imaging ,eye diseases ,PI-RADS ,medicine.anatomical_structure ,030220 oncology & carcinogenesis ,Radiology ,Biopsy, Large-Core Needle ,Neoplasm Grading ,business ,Core biopsy ,Follow-Up Studies - Abstract
Objective To determine the rate of malignancy after follow-up MR imaging of the prostate in PI-RADS 3 lesions without core biopsy and PI-RADS 4 lesions after negative initial core biopsy. Materials and methods We performed follow-up MRI in 46/72 (64%) patients with PI-RADS 3 lesions and 26/72 (36%) patients with PI-RADS 4 lesions in baseline MRI. Results The rate of malignancy in PI-RADS 3 lesions was 4% (2/46) and in PI-RADS 4 lesions 69% (18/26). Conclusions Follow-up MRI for PI-RADS 3 lesions should be performed. For PI-RADS 4 lesions with initial negative biopsy we recommend an instant repeat core biopsy.
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- 2016
6. Quantitative 2- and 3-dimensional analysis of pharmacokinetic model-derived variables for breast lesions in dynamic, contrast-enhanced MR mammography
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Horst J. Jaeger, Michael Forsting, Stefan Maderwald, Rainer Kimmig, A. Muehler, and E.A.M. Hauth
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Adult ,Gadolinium DTPA ,medicine.medical_specialty ,genetic structures ,media_common.quotation_subject ,Contrast Media ,computer.software_genre ,Diagnosis, Differential ,Lesion ,Breast Diseases ,Imaging, Three-Dimensional ,Voxel ,Image Interpretation, Computer-Assisted ,medicine ,Humans ,Contrast (vision) ,Mammography ,Radiology, Nuclear Medicine and imaging ,Aged ,Hue ,media_common ,Chi-Square Distribution ,medicine.diagnostic_test ,business.industry ,Magnetic resonance imaging ,General Medicine ,Middle Aged ,Magnetic Resonance Imaging ,Intensity (physics) ,Logistic Models ,ROC Curve ,Regression Analysis ,Female ,Radiology ,medicine.symptom ,business ,Nuclear medicine ,Quantitative analysis (chemistry) ,computer - Abstract
Purpose 2- and 3-dimensional evaluation of quantitative pharmacokinetic parameters derived from the Tofts model modeling dynamic contrast enhancement of lesions in MR mammography. Materials and methods In 95 patients, MR mammography revealed 127 suspicious lesions. The initial rate of enhancement was coded by color intensity, the post-initial enhancement change is coded by color hue. 2D and 3D analysis of distribution of color hue and intensity, vascular permeability and extracellular volume were performed. Results In 2D, malignant lesions showed significant higher number of bright red, medium red, dark red, bright green, medium green, dark green and bright blue pixels than benign lesions. In 3D, statistical significant differences between malignant and benign lesions was found for all this parameters. Vascular permeability was significant higher in malignant lesions than in benign lesions. Regression model using the 3D data found that the best discriminator between malignant and benign lesions was combined number of voxels and medium green pixels, with a sensitivity of 79.4% and a specificity of 83.1%. Conclusions Quantitative analysis of pharmacokinetic variables of contrast kinetics showed significant differences between malignant and benign lesions. 3D analysis showed superior diagnostic differentiation between malignant and benign lesions than 2D analysis. The parametric analysis using a pharmacokinetic model allows objective analysis of contrast enhancement in breast lesions.
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- 2008
7. MR-guided vacuum-assisted breast biopsy with a handheld biopsy system: clinical experience and results in postinterventional MR mammography after 24 h
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Horst J. Jaeger, R. Kimmig, F. Otterbach, Stefan Maderwald, Michael Forsting, J. Lubnau, and E. A. Hauth
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Adult ,Breast biopsy ,medicine.medical_specialty ,Time Factors ,Vacuum ,Biopsy ,Medizin ,Breast Neoplasms ,Magnetic Resonance Imaging, Interventional ,Lesion ,Image Processing, Computer-Assisted ,medicine ,Humans ,Mammography ,Radiology, Nuclear Medicine and imaging ,Prospective Studies ,Aged ,medicine.diagnostic_test ,business.industry ,Interventional radiology ,General Medicine ,Middle Aged ,Ductal carcinoma ,Vacuum-assisted breast biopsy ,Feasibility Studies ,Female ,Histopathology ,Radiology ,medicine.symptom ,business - Abstract
This prospective study evaluates the feasibility of the magnetic resonance (MR)-guided vacuum-assisted breast biopsy with a handheld vacuum-biopsy system and documents the biopsy results with MR mammography 24 h after the procedure. MR-guided biopsy was undertaken in 33 patients with 34 lesions on dynamic MR mammography. The interventions were performed with the handheld 10-gauge Vacora vacuum-biopsy system. In all cases, dynamic MR mammography was performed 24 h after the procedure to determine the extent of the lesion removal and to identify the lesions that were missed. In 5/34 (14.7%) lesions, biopsy was not performed because no suspicious lesion was identified on the day of biopsy. In 25/29 (86.2%) lesions, the biopsy was successfully performed with a complete removal in 4/29 (13.8%) and a partial removal of 21/29 (72.4%) lesions. In 4/29 (13.8%) interventions the lesion was missed with the biopsy. In one case, histopathology after surgical excision revealed ductal carcinoma in situ. Histopathology revealed 9/29 (31%) malignant and 20/29 (68.9%) benign lesions. MR-guided vacuum-assisted breast biopsy with the handheld Vacora vacuum-biopsy system is technically feasible in most cases. MR mammography 24 h after the biopsy should be performed in those cases in which the biopsy success is unclear immediately after the procedure.
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- 2007
8. Angiographische Verlaufskontrolle nach Stentimplantation zur Behandlung der Karotisbifurkationsstenose
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Andreas Christmann, C. Jansen, M. Schwarz, Michael Forsting, Horst J. Jaeger, Klaus Mathias, Elke Hauth, and Robert Drescher
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medicine.medical_specialty ,Selective angiography ,business.industry ,medicine.medical_treatment ,Carotid arteries ,Stent ,Hyperplasia ,medicine.disease ,Stenosis ,Restenosis ,Internal medicine ,Angioplasty ,medicine ,Cardiology ,Radiology, Nuclear Medicine and imaging ,cardiovascular diseases ,Radiology ,Prospective cohort study ,business - Abstract
PURPOSE The purpose of this prospective study was to determine the restenosis grade, the intima hyperplasia and the stent expansion via angiographic follow-up six months after carotid artery stenting. MATERIALS AND METHODS In 100 patients, angiographic follow-up was performed 5.9 months (range: 2.9-11.4 months) after carotid artery stenting. The restenosis grade, the intima hyperplasia and the stent expansion were measured by selective angiography of the treated carotid artery. RESULTS The mean restenosis grade was 16 % (range: 0-78 %). In 6 of 100 patients (6 %), a restenosis grade of > 50 % was measured. In 4 patients the restenosis grade was 50-70 %. In 2 patients the restenosis grade was > 70 %. In 91 of 100 patients (91 %), the restenosis was localized in the former area of stenosis of the carotid artery, and in 9 of 100 patients (9 %), the restenosis was localized in the cranial stent end. The mean grade of intima hyperplasia was 31 % (range: 2-70 %). The mean increase in stent expansion at the time of follow-up was 10 % (range: 0-59 %). No correlation was able to be determined between the grade of stenosis and the grade of restenosis (rho = 0.017, range: - 0.180-0.213), between the grade of residual stenosis and the grade of restenosis (rho = 0.257, range: 0.064-0.431) and between intima hyperplasia and the grade of restenosis (rho = 0.476, range: 0.309-0.615). CONCLUSIONS Carotid artery stenting is associated with a low incidence of high-grade restenosis 6 months after an intervention. The intima hyperplasia, which can be observed in each Wallstent, is partly compensated by the expansion of the self-expandable stent. Without a correlation between the grade of residual stenosis and the grade of restenosis, low-grade residual stenosis can be accepted. Therefore, we recommend undersized postdilation of the Wallstent.
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- 2006
9. Evaluation of quantitative parametric analysis for characterization of breast lesions in contrast-enhanced MR mammography
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Stefan Maderwald, Horst J. Jaeger, Michael Forsting, C. Stockamp, E. A. Hauth, A. Mühler, and R. Kimmig
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Adult ,Gadolinium DTPA ,medicine.medical_specialty ,media_common.quotation_subject ,Color ,Contrast Media ,Breast Neoplasms ,Statistics, Nonparametric ,Diagnosis, Differential ,Region of interest ,Image Processing, Computer-Assisted ,medicine ,Humans ,Mammography ,Contrast (vision) ,Radiology, Nuclear Medicine and imaging ,Aged ,Neuroradiology ,media_common ,Hue ,Chi-Square Distribution ,medicine.diagnostic_test ,Pixel ,business.industry ,Ultrasound ,Magnetic resonance imaging ,General Medicine ,Middle Aged ,Magnetic Resonance Imaging ,Female ,sense organs ,Radiology ,business ,Software - Abstract
Our aim was to evaluate quantitative parametric analysis for characterization of breast lesions in contrast-enhanced magnetic resonance (MR) mammography. In 62 patients, contrast-enhanced MR mammography revealed 75 suspicious lesions, of which 18 were benign and 57 were malignant. The quantitative parametric analysis delineates signal intensity changes of contrast-enhanced lesions on a pixel-by-pixel basis. The initial rate of enhancement is coded by color intensity: a slow rate is coded to dark; a fast rate, bright. The postinitial enhancement change is coded by color hue: blue for increasing signal intensity, green for plateau, and red for decrease in signal intensity. Malignant lesions showed a significantly higher number of bright-red (P = 0.004) and medium-red (P0.001) pixels than benign lesions. Benign lesions showed significantly more blue pixels than did malignant lesions (P = 0.010). Of the 75 lesions, 72 (96%) showed heterogeneous distribution of pixel color hue. Quantitative parametric analysis of contrast kinetics in lesions can replace the subjective manual region of interest (ROI) method and makes a step toward standardization of MR mammography. It allows quantitative evaluation of different contrast kinetics parameters in contrast-enhanced breast lesions.
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- 2006
10. MR imaging of the uterus and cervix in healthy women: Determination of normal values
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E. A. Hauth, Silke Lange, Hanna Libera, Horst J. Jaeger, and Michael Forsting
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Adult ,medicine.medical_specialty ,media_common.quotation_subject ,Uterus ,Cervix Uteri ,Endometrium ,Age Distribution ,Reference Values ,medicine ,Humans ,Radiology, Nuclear Medicine and imaging ,Adenomyosis ,Prospective Studies ,Cervix ,Pelvis ,Menstrual cycle ,Aged ,media_common ,Gynecology ,Leiomyoma ,urogenital system ,business.industry ,Myometrium ,General Medicine ,Middle Aged ,medicine.disease ,Magnetic Resonance Imaging ,female genital diseases and pregnancy complications ,Menstrual cycle phase ,medicine.anatomical_structure ,Uterine Neoplasms ,Radiographic Image Interpretation, Computer-Assisted ,Female ,business - Abstract
The purpose of this study was to establish normal values for the volume of the uterus and cervix in MRI based on age and the menstrual cycle phase. We performed MRI of the pelvis in 100 healthy women. For the uterus, they were further divided into two groups: one with myomas and/or adenomyosis and one without either. The volume of the uterus and cervix and thickness of the uterine wall layers were analysed by age and the menstrual cycle phase. The mean volume of the uterus in both groups and the cervix significantly increased with age to reach its peak at 41-50 years, and then dropped. Likewise, the thickness of the endometrium and the junctional zone, but not the myometrium, significantly increased until 41-50 years, and then decreased. When we compared the volume of the uterus and cervix and the thickness of the uterine wall layers between the two phases of the menstrual cycle, we found no significant differences. The volume of the uterus and cervix and the thickness of the endometrium and junctional zone differ significantly with age, but not between the two phases of the menstrual cycle. Knowledge of MRI-related normal values can be expected to aid the early identification of uterine pathologies.
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- 2006
11. Evaluation of the three-time-point method for diagnosis of breast lesions in contrast-enhanced MR mammography
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Rainer Kimmig, Michael Forsting, Stefan Maderwald, Christin Stockamp, Jörg Barkhausen, Andreas Mühler, Horst J. Jaeger, and E. A. Hauth
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Adult ,Gadolinium DTPA ,medicine.medical_specialty ,Time Factors ,Contrast enhancement ,media_common.quotation_subject ,Contrast Media ,Breast Neoplasms ,Lesion ,Imaging, Three-Dimensional ,Text mining ,Image Interpretation, Computer-Assisted ,Humans ,Contrast (vision) ,Medicine ,Mammography ,Radiology, Nuclear Medicine and imaging ,Breast ,Prospective Studies ,Time point ,Aged ,media_common ,Observer Variation ,medicine.diagnostic_test ,Kinetic information ,business.industry ,Carcinoma, Ductal, Breast ,Reproducibility of Results ,Middle Aged ,Image Enhancement ,Magnetic Resonance Imaging ,Female ,Radiology ,medicine.symptom ,business ,Nuclear medicine ,Follow-Up Studies ,Mr mammography - Abstract
Purpose: To evaluate the three-time-point (3TP) method for diagnosis of breast lesions detected on contrast-enhanced MR mammography. Materials and Methods: MR imaging was performed in 40 women with 120 suspected breast lesions in mammography and/or sonography. The contrast kinetics was converted by 3TP software on a pixel-by-pixel basis into color-coded images. Lesion diagnosis was made by analysis of color intensity and color hue. The 3TP results were compared with the results of the region-of-interest (ROI) method. In 16 patients, we were able to correlate the results with histopathological findings. Results: The 3TP method could successfully be performed in all MR mammographies. Forty (33%) lesions had a diameter of less than 5 mm, 56 (47%) lesions between 5 and 10 mm, and 24 (20%) lesions were greater than 1 cm. Of all 120 lesions, 65 (54%) showed heterogeneous contrast enhancement. In 117 (97%) of all 120 lesions the results of ROI and the automated 3TP method were considered equivalent. However, in three lesions the manual ROI differed from the 3TP method. After a second, repeated manual ROI placement, we were able to confirm equivalent results with the 3TP images as well. Conclusions: The 3TP method automatically and reliably converts contrast kinetic information of the entire breast into a color-coded image. The 3TP method presents kinetic information of the entire dynamic series in an easy-to-interpret format and this automated method may allow to forego time-consuming and sometimes subjective manual ROI placements. This method displays the heterogeneity of the contrast enhancement pattern often observed in malignant lesions and makes it usable as diagnostic criterion.
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- 2006
12. Complications and Follow-up after Unprotected Carotid Artery Stenting
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Michael Schwarz, E. A. Hauth, Klaus Mathias, Robert Drescher, Christian Jansen, H. Martin Gissler, Horst J. Jaeger, and Michael Forsting
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Adult ,Male ,medicine.medical_specialty ,Stroke rate ,Carotid arteries ,Asymptomatic ,Functional Laterality ,Restenosis ,Preoperative Care ,medicine ,Humans ,Carotid Stenosis ,Radiology, Nuclear Medicine and imaging ,Major complication ,Prospective cohort study ,Stroke ,Aged ,Aged, 80 and over ,business.industry ,Mortality rate ,Cerebral Infarction ,Middle Aged ,medicine.disease ,Magnetic Resonance Imaging ,Surgery ,Treatment Outcome ,Female ,Stents ,medicine.symptom ,Tomography, X-Ray Computed ,Cardiology and Cardiovascular Medicine ,business - Abstract
This prospective study was undertaken to determine the success rate, complications, and outcome of carotid artery stenting (CAS) without the use of cerebral protection devices. During 12 months, 94 high-grade stenoses of the carotid artery in 91 consecutive patients were treated. Sixty-six (70%) of the stenoses were symptomatic and 28 (30%) were asymptomatic. In all 94 carotid stenoses CAS was successfully performed. During the procedure and within the 30 days afterwards, there were 2 deaths and 3 major strokes in the 66 symptomatic patients, resulting in a combined death and stroke rate of 5 of 66 (7%). Only one of these complications, a major stroke, occurred during the procedure. In the 6-month follow-up, one additional major stroke occurred in a originally symptomatic patient resulting in a combined death and stroke rate of 6 of 66 (10%) for symptomatic patients at 6 months. No major complications occurred in asymptomatic patients during the procedure or in the 6-month follow-up period. At 6 months angiographic follow-up the restenosis rate with a degree of >50% was 3 of 49 (6%) and the rate with a degree of ≥70% was 1 of 49 (2%). Cerebral embolization during CAS is not the only cause of the stroke and death rate associated with the procedure. The use of cerebral protection devices during the procedure may therefore not prevent all major complications following CAS.
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- 2006
13. Carotid Artery Stenting Protected With an Emboli Containment System
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Horst J. Jaeger, Claudio Schönholz, Patrick L. Whitlow, Hugo Londero, Oscar Mendiz, P Lylyk, Klaus Mathias, José Milei, and Juan C. Parodi
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Male ,medicine.medical_specialty ,medicine.medical_treatment ,Hemorrhage ,Carotid endarterectomy ,Balloon ,Catheterization ,Blood Vessel Prosthesis Implantation ,Occlusion ,medicine ,Humans ,Carotid Stenosis ,cardiovascular diseases ,Particle Size ,Stroke ,Aged ,Advanced and Specialized Nursing ,Vascular disease ,business.industry ,Stent ,Thrombosis ,medicine.disease ,Surgery ,Stenosis ,Carotid Arteries ,Treatment Outcome ,Intracranial Embolism ,Ischemic Attack, Transient ,Female ,Stents ,Neurology (clinical) ,Radiology ,Carotid stenting ,Cardiology and Cardiovascular Medicine ,business ,Filtration - Abstract
Background and Purpose — Fear of distal embolization and stroke has aroused concern regarding carotid stenting. Devices to protect the cerebral circulation may make carotid stenting safer. Methods — A multidisciplinary study group tested a balloon occlusion-aspiration emboli entrapment device in conjunction with carotid stenting. The device consists of an elastomeric balloon on a steerable wire with a detachable adapter that inflates and deflates the distal temporary occlusion balloon. An aspiration catheter is used to remove trapped emboli after stenting and before occlusion balloon deflation. Results — Seventy-five patients with severe internal carotid artery stenosis were treated with stents deployed with this cerebrovasculature protection system. All 75 patients (100%) had grossly visible particulate material aspirated, and all were treated successfully without major or minor stroke or death at 30 days. Preintervention stenosis was 81±10%, and residual stenosis was 5±7%. Nine patients (12%) had angiographic evidence of thrombus before intervention, but no patient had thrombus or vessel cutoff after the procedure. Four patients (5%) developed transient neurological symptoms during protection balloon occlusion, but symptoms resolved with balloon deflation. The 22 to 667 particles aspirated per patient ranged from 3.6 to 5262 μm in maximum diameter (mean, 203±256 μm). These particles included fibrous plaque debris, lipid or cholesterol vacuoles, and calcific plaque fragments. Conclusions — Protected carotid stenting was performed successfully and safely in this study early in the experience with cerebrovascular protection devices. Particulate emboli are frequent with stenting, and cerebral protection will likely be necessary to minimize stroke. Randomized trials comparing protected carotid stenting with endarterectomy are warranted.
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- 2002
14. Clinical results of carotid artery stenting with a nitinol self-expanding stent (SMART stent)
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Georg Bockisch, Robert Drescher, Horst J. Jaeger, Eren Demirel, Martin H. Gissler, E. A. Hauth, and Klaus Mathias
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Male ,medicine.medical_specialty ,medicine.medical_treatment ,Blood Vessel Prosthesis Implantation ,Restenosis ,medicine.artery ,Alloys ,Humans ,Medicine ,Carotid Stenosis ,Radiology, Nuclear Medicine and imaging ,Prospective Studies ,cardiovascular diseases ,Common carotid artery ,Aged ,Neuroradiology ,Aged, 80 and over ,medicine.diagnostic_test ,business.industry ,Stent ,Interventional radiology ,General Medicine ,Middle Aged ,equipment and supplies ,medicine.disease ,Surgery ,Radiography ,Stenosis ,Carotid Arteries ,Treatment Outcome ,Angiography ,Female ,Stents ,Radiology ,Internal carotid artery ,business - Abstract
Our objective was to assess the technical feasibility and the clinical results of internal carotid artery (ICA) stenting using a nitinol self-expanding stent (SMART stent). In 13 patients 13 high-grade stenoses of the internal carotid artery were treated via an implantation of a SMART stent. In all cases a predilation of the stenosis and a postdilation within the stent were performed. Follow-up examinations were carried out in all patients after a period of 6 months. In each case the implantation of the stent was performed without technical complications. In 12 of 13 cases the stent was placed in the patients' internal carotid artery, in 1 case from the internal to the common carotid artery (CCA). The average degree of stenosis of 78% (70-95%) was reduced to an average of 2.8% (0-21%). The 6-month follow-up angiography showed an average degree of restenosis of 11.8% (0-29%) in 8 of 13 patients. Duplex sonography in the remaining 5 patients demonstrated patent stents. One patient showed brief neurological symptoms during the intervention. No further complications occurred during follow-up time. Treatment of internal carotid artery stenosis with the SMART stent seems technically feasible, safe, and promises long-term patency.
- Published
- 2002
15. Rectum and Sigmoid Colon Necrosis Due to Cholesterol Embolization after Implantation of an Aortic Stent-Graft
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Gerhard Neumann, Klaus Mathias, Lutz-Dietrich Walther, Horst J. Jaeger, and H. Martin Gissler
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medicine.medical_specialty ,Necrosis ,medicine.medical_treatment ,Myocardial Infarction ,Rectum ,Prosthesis ,Blood Vessel Prosthesis Implantation ,Aortic aneurysm ,Fatal Outcome ,Colon, Sigmoid ,Humans ,Medicine ,Radiology, Nuclear Medicine and imaging ,cardiovascular diseases ,Embolization ,Embolism, Cholesterol ,business.industry ,Sigmoid colon ,Middle Aged ,medicine.disease ,surgical procedures, operative ,medicine.anatomical_structure ,Embolism ,cardiovascular system ,Female ,Stents ,Radiology ,medicine.symptom ,Cardiology and Cardiovascular Medicine ,business ,Colitis, Ischemic ,Aortic Aneurysm, Abdominal ,Follow-Up Studies ,Abdominal surgery - Abstract
Endovascular treatment of abdominal aortic aneurysms (AAAs) with stent-grafts is increasingly performed. Recent studies have shown that stent-graft placement for AAA is technically feasible and can effectively exclude aneurysms from the circulation. However, complications related to the procedure, such as graft thrombosis, migration of the prosthesis, peripheral embolization, and leaks with incomplete exclusion of the aneurysmal sac, have been reported. We report a case of rectum and sigmoid colon necrosis with fatal outcome due to cholesterol embolization after implantation of a stent-graft for an infrarenal AAA.
- Published
- 1999
16. In Vitro Model for the Evaluation of Inferior Vena Cava Filters: Effect of Experimental Parameters on Thrombus-Capturing Efficacy of the Vena Tech-LGM Filter
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Andreas Christmann, Horst J. Jaeger, Rolf K. H. Kinne, Klaus Mathias, Marius Geller, Thomas Mair, and Stefan Kolb
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medicine.medical_specialty ,Vena Cava Filters ,Vena cava ,In Vitro Techniques ,Inferior vena cava ,In vitro model ,medicine ,Radiology, Nuclear Medicine and imaging ,cardiovascular diseases ,Thrombus ,business.industry ,Thrombosis ,medicine.disease ,Models, Structural ,Logistic Models ,medicine.vein ,Flow velocity ,Peak velocity ,Filter (video) ,cardiovascular system ,Radiology ,Cardiology and Cardiovascular Medicine ,business ,Filtration ,Biomedical engineering - Abstract
Purpose To determine the experimental parameters in an in vitro model that influence the thrombus-capturing efficacy of the Vena Tech-LGM filter. Materials and Methods The Vena Tech-LGM filter was evaluated in an in vitro model of the vena cava with a computer-controlled flow system with a total of 5,200 thrombi. The influences of the following experimental parameters on the capture rate were analyzed with a multiple logistic regression model: type of testing (single, double, and multiple shot testing), thrombus diameter and length, IVC diameter and orientation, flow quality and quantity, flow velocity, and the length of the prepositioned thrombus. Results A significant influence on the capture rate could be demonstrated for the type of testing, the thrombus diameter and length, the IVC diameter, and with double shot testing for the length of the prepositioned thrombus and the IVC orientation. The flow quality and the peak velocity were not significant. Based on these results, a protocol for in vitro testing of IVC filters was designed. Conclusions Experimental parameters influence the thrombus-capturing efficacy of the Vena Tech-LGM filter and should be taken into account when in vitro testing is performed.
- Published
- 1998
17. A Physiologic In Vitro Model of the Inferior Vena Cava with a Computer-Controlled Flow System for Testing of Inferior Vena Cava Filters
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Horst J. Jaeger, Rolf K. H. Kinne, Klaus Mathias, Marius Geller, Andreas Christmann, and Thomas Mair
- Subjects
medicine.medical_specialty ,Vena Cava Filters ,Computer science ,Video Recording ,Pulsatile flow ,Vena Cava, Inferior ,Inferior vena cava ,In vitro model ,Thromboembolism ,Occlusion ,medicine ,Humans ,Radiology, Nuclear Medicine and imaging ,Thrombus ,Electronic Data Processing ,Continuous monitoring ,Models, Cardiovascular ,Reproducibility of Results ,Equipment Design ,General Medicine ,medicine.disease ,Centrifugal pump ,Surgery ,Models, Structural ,medicine.vein ,Filter (video) ,cardiovascular system ,Feasibility Studies ,Blood Flow Velocity ,Biomedical engineering - Abstract
RATIONALE AND OBJECTIVES The authors develop a physiologic in vitro model of the inferior vena cava (IVC) for testing of filters. METHODS The model is driven by a centrifugal pump. A computer-controlled electromagnetic valve is used for generation of different flow patterns. Limitation of the pressure increase in case of IVC occlusion is achieved by a bypass circuit. A glycerin solution is used for perfusion. Artificial clots are made from polyacrylamide gel. Data acquisition includes continuous monitoring of flow and difference pressure over the filter and video recording of the testing events. RESULTS The model can generate constant and pulsatile flows. The pressure increase can be limited to 70 mm Hg in case of occlusion. Calculation of the flow velocities in the IVC is possible. A classification of thrombus capturing is presented. The testing of most of the results are reproducible. CONCLUSIONS The in vitro model simulates the physiologic conditions in the IVC. It can be used for comparative testing of different filters and the evaluation of new filter designs.
- Published
- 1997
18. Therapeutic Occlusion of an Internal Carotid Artery with a High-Grade Stenosis Using Guglielmi Detachable Coils
- Author
-
Robert Drescher, Klaus Mathias, E. A. Hauth, Michael Forsting, and Horst J. Jaeger
- Subjects
Male ,medicine.medical_specialty ,Therapeutic Occlusion ,medicine.medical_treatment ,medicine.artery ,medicine ,Humans ,Carotid Stenosis ,Radiology, Nuclear Medicine and imaging ,In patient ,Embolization ,Endovascular treatment ,Contraindication ,Aged ,business.industry ,medicine.disease ,Embolization, Therapeutic ,Cerebral Angiography ,Surgery ,Stenosis ,Treatment Outcome ,Embolism ,cardiovascular system ,Radiology ,Internal carotid artery ,Cardiology and Cardiovascular Medicine ,business ,Carotid Artery, Internal - Abstract
We present a patient with a symptomatic, high-grade stenosis of the internal carotid artery (ICA) and contraindication for open surgery. Endovascular treatment was attempted, but stent placement was not possible. In view of good collateral flow to the related hemisphere, embolization of the stenosis of the ICA with Guglielmi detachable coils (GDCs) was performed to occlude the vessel. No complications occurred during the procedure or in the 1-year follow-up period. In cases where open surgery or endovascular treatment of a stenosis of the ICA are contraindicated or not possible, therapeutic occlusion of the stenotic ICA could be an alternative treatment option in patients with good collateral flow.
- Published
- 2005
19. Sequential transarterial chemoembolization for unresectable advanced hepatocellular carcinoma
- Author
-
Francisco Castañeda, Frank Hasse, Gerhard Blumhardt, Dietrich Loehlein, Horst J. Jaeger, Klaus Mathias, and Ulrich-Martin Mehring
- Subjects
Adult ,Male ,medicine.medical_specialty ,Carcinoma, Hepatocellular ,medicine.medical_treatment ,Antineoplastic Combined Chemotherapy Protocols ,medicine ,Carcinoma ,Humans ,Radiology, Nuclear Medicine and imaging ,Prospective Studies ,Embolization ,Chemoembolization, Therapeutic ,Prospective cohort study ,Aged ,Epirubicin ,Chemotherapy ,business.industry ,Liver Neoplasms ,Iodized Oil ,Middle Aged ,Prognosis ,medicine.disease ,Surgery ,Clinical trial ,Hepatocellular carcinoma ,Lipiodol ,Feasibility Studies ,Female ,Cisplatin ,Cardiology and Cardiovascular Medicine ,business ,medicine.drug - Abstract
The aim of this prospective study was to evaluate the feasibility, safety, and efficacy of sequential transarterial chemoembolization (TACE) for patients with unresectable advanced hepatocellular carcinoma (HCC). Twenty-one consecutive patients with unresectable T3 and T4 HCC were treated by sequential TACE (median time interval between treatments 7 weeks) up to six times with an emulsion of lipiodol, epirubicin, and cisplatin. All TACE procedures were performed as unilobar or whole-liver chemoembolization. An average of 3.9 TACE procedures were performed per patient. One primary and two secondary technical failures occurred. No procedural death was observed. After exclusion of the patient with the primary technical failure and 3 patients with extrahepatic disease, the survival rates for the remaining 17 patients at 6, 12, 18, and 24 months were 70.6%, 52.9%, 44.1%, and 33.1%, respectively. Sequential TACE is a safe procedure in patients with unresectable advanced HCC and feasible in most cases. It seems to prolong the survival time compared with historical series of untreated patients.
- Published
- 1996
20. Multiparametric MRI of the prostate with three functional techniques in patients with PSA elevation before initial TRUS-guided biopsy
- Author
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Meinrad Beer, Elke Hauth, Stefan Bernand, Horst Hohmuth, Corina Cozub-Poetica, and Horst J. Jaeger
- Subjects
Image-Guided Biopsy ,Male ,In vivo magnetic resonance spectroscopy ,medicine.medical_specialty ,Magnetic Resonance Spectroscopy ,Contrast Media ,urologic and male genital diseases ,Sensitivity and Specificity ,Prostate cancer ,Prostate ,Biopsy ,medicine ,Humans ,Radiology, Nuclear Medicine and imaging ,Sampling (medicine) ,Prospective Studies ,Prospective cohort study ,Aged ,Ultrasonography ,Full Paper ,medicine.diagnostic_test ,business.industry ,Ultrasound ,Prostatic Neoplasms ,Reproducibility of Results ,Cancer ,General Medicine ,Middle Aged ,Prostate-Specific Antigen ,Image Enhancement ,medicine.disease ,Magnetic Resonance Imaging ,Diffusion Magnetic Resonance Imaging ,medicine.anatomical_structure ,Radiology ,Neoplasm Recurrence, Local ,business - Abstract
Multiparametric MRI (mp-MRI) of the prostate is increasingly being used for local staging and detection of recurrence of prostate cancer (PCA). In patients with elevated prostate-specific antigen (PSA), mp-MRI could provide information on the position of the cancer, allowing adjustments to be made to the needle depth and direction before repeat transrectal ultrasound (TRUS)-guided biopsy to ensure accurate sampling of lesions. The purpose of the prospective study was to evaluate mp-MRI of the prostate in patients with PSA elevation before initial TRUS-guided biopsy.mp-MRI was performed in 94 patients using a 1.5-T scanner (MAGNETOM Aera(®); Siemens Healthcare, Erlangen, Germany) and 16-channel phased-array body coil (Siemens Healthcare). T2 weighted images (T2WI), diffusion-weighted imaging (DWI), dynamic contrast-enhanced (DCE) MRI and MR spectroscopy were obtained. TRUS-guided random biopsies and additional targeted biopsies of suspicious MRI areas were performed.Additional targeted biopsies were obtained in 17 of 43 (40%) patients with PCA. 11 of 17 targeted biopsies contained PCA. 5 of 11 PCAs were diagnosed only by additional targeted biopsies. Sensitivity of mp-MRI in patients was 97.7% and specificity was 11.8%. mp-MRI was false negative in one patient. Sensitivity of mp-MRI in 207 lesions was 80.9% and specificity was 44.7%. In a logistic regression model, the apparent diffusion coefficient value was the only significant parameter to differentiate malignant and benign lesions.mp-MRI should be performed in patients with PSA elevation before initial TRUS-guided biopsy to allow additional targeted biopsies from suspicious areas of MRI. We recommend mp-MRI with T2WI, DWI, DCE MRI and MR spectroscopy. DWI as the most reliable technique should be used in every mp-MRI.DWI is the most reliable technique in mp-MRI of the prostate.
- Published
- 2015
21. Angioplasty or Stenting of Extra- and Intracranial Vertebral Artery Stenoses
- Author
-
Klaus Mathias, E. A. Hauth, Horst J. Jaeger, Christian Jansen, Robert Drescher, and H. Martin Gissler
- Subjects
Male ,Reoperation ,medicine.medical_specialty ,Subarachnoid hemorrhage ,Brachial Artery ,medicine.medical_treatment ,Vertebral artery ,Dissection (medical) ,Balloon ,Asymptomatic ,Blood Vessel Prosthesis Implantation ,Postoperative Complications ,Germany ,Angioplasty ,medicine.artery ,Vertebrobasilar Insufficiency ,medicine ,Humans ,Radiology, Nuclear Medicine and imaging ,Aged ,medicine.diagnostic_test ,business.industry ,Brain ,Middle Aged ,medicine.disease ,Combined Modality Therapy ,Survival Analysis ,Cerebral Angiography ,Surgery ,Femoral Artery ,Stenosis ,Treatment Outcome ,Feasibility Studies ,Female ,Stents ,Radiology ,medicine.symptom ,Cardiology and Cardiovascular Medicine ,business ,Angioplasty, Balloon ,Follow-Up Studies ,Cerebral angiography - Abstract
Purpose: To determine the feasibility and safety of angioplasty or angioplasty and stenting of extra- and intracranial vertebral artery (VA) stenosis. Methods: In 16 consecutive patients (9 men, 7 women; mean age 61 years, range 49–74 years) 16 stenotic VAs were treated with angioplasty or angioplasty and stenting. Eleven stenoses were localized in V1 segment, 1 stenosis in V2 segment and 4 stenoses in V4 segment of VA. Fourteen VA stenoses were symptomatic, 2 asymptomatic. The etiology of the stenoses was atherosclerotic in all cases. Results: Angioplasty was performed in 8 of 11 V1 and 2 of 4 V4 segments of the VA. In 3 of 11 V1 segments and 2 of 4 V4 segments of the VA we combined angioplasty with stenting. The procedures were successfully performed in 14 of 16 VAs (87%). Complications were asymptomatic vessel dissection resulting in vessel occlusion in 1 of 11 V1 segments and asymptomatic vessel dissection in 2 of 4 V4 segments of the VA. One patient died in the 24-hr period after the procedure because of subarachnoid hemorrhage as a complication following vessel perforation of the treated V4 segment. Conclusion: Angioplasty or angioplasty and stenting of extracranial VA stenoses can be performed with a high technical success rate and a low complication rate. In intracranial VA stenosis the procedure is technically feasible but complications can be life-threatening. The durability and procedural complication rates of primary stenting without using predilation in extra- and intracranial VA stenosis should be defined in the future.
- Published
- 2003
22. Clinical results of cerebral protection with a filter device during stent implantation of the carotid artery
- Author
-
Robert Drescher, Horst J. Jaeger, E. A. Hauth, Eren Demirel, Hans Martin Gissler, Klaus Mathias, and George Bockisch
- Subjects
Male ,medicine.medical_specialty ,Arterial disease ,Carotid arteries ,Radiography, Interventional ,Catheterization ,Risk Factors ,medicine ,Stent implantation ,Humans ,Radiology, Nuclear Medicine and imaging ,Carotid Stenosis ,cardiovascular diseases ,Prospective Studies ,Aged ,business.industry ,Vascular disease ,Brain ,Middle Aged ,medicine.disease ,Magnetic Resonance Imaging ,Cerebral Angiography ,Stenosis ,Intracranial Embolism ,cardiovascular system ,Female ,Stents ,Radiology ,Cardiology and Cardiovascular Medicine ,business ,Angioplasty, Balloon ,Carotid Artery, Internal ,Filtration - Abstract
To assess the technical feasibility and the clinical results of cerebral protection with the Angioguard emboli-capture guidewire system during carotid artery stenting (CAS) for high-grade stenoses.In 20 patients 20 stenoses of the internal carotid artery were treated with stent implantation. In all patients diffusion-weighted (DW) magnetic resonance imaging (MRI) of the brain was performed before and 24 hr after the procedure.The filter device was effectively employed during all steps of the procedure in 16 of 20 patients, in two only postdilation could be protected, and in two no protection was possible. After three of the 20 procedures new ipsilateral cerebral lesions were visualized by DW-MRI. No new permanent neurologic deficits occurred.Cerebral protection with the filter device is technically feasible in most cases. DW-MRI demonstrated new cerebral lesions indicating the occurrence of cerebral microemboli during the protected procedures. Further investigations are necessary to determine whether the use of the cerebral protection device will improve the results of CAS.
- Published
- 2002
23. Congenital absence of the internal carotid artery and the basilar artery with persistent trigeminal artery associated with coarctation of the aorta
- Author
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Hans Martin Gissler, Klaus Mathias, U.-M. Mehring, and Horst J. Jaeger
- Subjects
Adult ,Intracranial Arteriovenous Malformations ,medicine.medical_specialty ,Cerebral arteries ,Coarctation of the aorta ,Collateral Circulation ,Aortic Coarctation ,Internal medicine ,medicine.artery ,Cerebellum ,medicine ,Basilar artery ,Humans ,Radiology, Nuclear Medicine and imaging ,medicine.diagnostic_test ,business.industry ,General Medicine ,Arteries ,medicine.disease ,Collateral circulation ,Cerebral Angiography ,Anterior communicating artery ,medicine.anatomical_structure ,Basilar Artery ,Cerebrovascular Circulation ,cardiovascular system ,Cardiology ,Trigeminal artery ,Female ,Radiology ,Internal carotid artery ,business ,Carotid Artery, Internal ,Cerebral angiography - Abstract
We report a case of congenital absence of the cervical and petrous part of the left internal carotid artery, the middle and proximal part of the basilar artery, and the V4 segment of the left vertebral artery associated with a left persistent trigeminal artery and a coarctation of the aorta. The left cerebral vessels are supplied via the anterior communicating artery and the left persistent trigeminal artery. The coexisting coarctation of the aorta led to a subclavian steal phenomenon. The alteration of the cerebral hemodynamics has to be taken in consideration when performing cerebral angiography and surgical correction in such a case.
- Published
- 2000
24. Digital chest radiography with a large-area flat-panel silicon X-ray detector: clinical comparison with conventional radiography
- Author
-
Horst J. Jaeger, Andreas Jacobs, Andreas Christmann, Svenja Hennigs, Hans Martin Gissler, Reinhard Classen, Klaus Mathias, and Marietta Garmer
- Subjects
Adult ,Male ,medicine.medical_specialty ,Silicon ,Radiography ,X-ray detector ,Hilum (biology) ,Image processing ,Sensitivity and Specificity ,Digital image ,medicine ,Humans ,Radiology, Nuclear Medicine and imaging ,Neuroradiology ,Aged ,Costodiaphragmatic recess ,Aged, 80 and over ,Observer Variation ,business.industry ,Ultrasound ,General Medicine ,Middle Aged ,Radiographic Image Enhancement ,medicine.anatomical_structure ,Female ,Radiography, Thoracic ,Radiology ,business - Abstract
This was a radiologists' preference study to compare a digital chest radiography system that utilizes a large-area silicon flat-panel detector with conventional radiography for visualizing anatomic regions of the chest. Conventional and digital posteroanterior (PA) and lateral chest radiographs were obtained in 115 patients. The PA and lateral image pairs were compared independently by three radiologists rating the overall appearance, 11 anatomic regions in the PA, and 9 in the lateral views. Statistical analysis was performed with the Wilcoxon signed-rank test with Bonferroni-Holm adjustment (p=0.05). For the PA view, the digital system performed significantly better for the overall appearance and for all anatomic regions except for the peripheral pulmonary vasculature and hilum, where no significant difference was found. For the lateral digital images, the regions trachea, costodiaphragmatic recess, and hilum were rated significantly worse. The regions retrosternal and retrocardiac lung were rated significantly better. The other regions and the overall appearance showed no significant differences. The described digital chest radiography system showed statistically superior visualization of anatomic regions for PA and an ambiguous performance for lateral images as compared with conventional radiography. After changing some image processing parameters for the lateral view, this system may be suitable for digitalization of chest radiography.
- Published
- 2000
25. Cervical diastematomyelia and syringohydromyelia in a myelomeningocele patient
- Author
-
Horst J. Jaeger, A. Schmitz-Stolbrink, and Klaus Mathias
- Subjects
medicine.medical_specialty ,Weakness ,Meningomyelocele ,Adolescent ,Spina Bifida Occulta ,Lumbar ,Medicine ,Humans ,Radiology, Nuclear Medicine and imaging ,Neuroradiology ,Diastematomyelia ,medicine.diagnostic_test ,business.industry ,Brain ,Magnetic resonance imaging ,Interventional radiology ,General Medicine ,medicine.disease ,Magnetic Resonance Imaging ,Syringomyelia ,Surgery ,Hydrocephalus ,Shunting ,Spinal Cord ,Female ,Radiology ,medicine.symptom ,business - Abstract
A case of cervical diastematomyelia and syringohydromyelia in a 16-year-old female myelomeningocele patient is reported. Progressive weakness of the upper extremity led to an MR examination of the brain and spine, which revealed hydrocephalus, Chiari II malformation, cervical diastematomyelia with a syringohydromyelic cavity in each hemicord and a large dural sac in the lumbar region. Operative therapy consisted of detethering and shunting of the two syringes. Soon after surgery her symptoms improved. The need for early complete MR imaging of myelomeningocele patients presenting with new symptoms is emphasized.
- Published
- 1997
26. Gastric leiomyosarcoma in a child
- Author
-
Annette Schmitz-Stolbrink, Matthias Albrecht, Horst J. Jaeger, and Klaus Mathias
- Subjects
Leiomyosarcoma ,Male ,medicine.medical_specialty ,Presumptive diagnosis ,Left upper quadrant ,Contrast Media ,Computed tomography ,Patient Care Planning ,Diagnosis, Differential ,Necrosis ,Gastrectomy ,Stomach Neoplasms ,Gastroscopy ,medicine ,Humans ,Radiology, Nuclear Medicine and imaging ,Ultrasonography ,medicine.diagnostic_test ,Leiomyoma ,business.industry ,Stomach ,Calcinosis ,General Medicine ,medicine.disease ,body regions ,medicine.anatomical_structure ,Gastric Leiomyosarcoma ,Child, Preschool ,Radiology ,business ,Tomography, X-Ray Computed ,Follow-Up Studies - Abstract
Gastric leiomyosarcoma is a rare tumor in pediatric patients. The histological differentiation between leiomyoma and leiomyosarcoma is difficult. Computed tomography may allow the presumptive diagnosis of leiomyosarcoma to be made preoperatively and the surgical treatment can be planned in advance. We report a case of gastric leiomoysarcoma in a 2-year old boy. Ultrasonography and computed tomography demonstrated an inhomogeneous mass with areas of tumor necrosis and calcifications in the left upper quadrant.
- Published
- 1996
27. Bilateral subclavian steal syndrome: Treatment with percutaneous transluminal angioplasty and stent placement
- Author
-
Horst J. Jaeger, Klaus Mathias, and Udo Kempkes
- Subjects
Male ,medicine.medical_specialty ,Percutaneous ,medicine.medical_treatment ,Subclavian Artery ,Transluminal Angioplasty ,Balloon ,Subclavian Steal Syndrome ,medicine.artery ,Angioplasty ,otorhinolaryngologic diseases ,medicine ,Humans ,Stent implantation ,Radiology, Nuclear Medicine and imaging ,cardiovascular diseases ,Subclavian artery ,Aged ,business.industry ,medicine.disease ,Surgery ,Radiography ,body regions ,SSS ,surgical procedures, operative ,cardiovascular system ,Stents ,Radiology ,Cardiology and Cardiovascular Medicine ,business ,Subclavian steal syndrome ,Angioplasty, Balloon - Abstract
A 66-year-old man presented with bilateral subclavian steal syndrome (SSS) due to proximal subclavian artery occlusions. He was treated by percutaneous transluminal balloon angioplasty (PTA) and stent implantation in the left subclavian artery and by PTA alone in the right subclavian artery. We could demonstrate that interventional treatment of symptomatic bilateral SSS is possible. If PTA alone is insufficient, stent implantation should be considered.
- Published
- 1994
28. Lead dislodgment of a permanent pacemaker due to removal of a temporary pacing electrode
- Author
-
Hans-Jurgen Krabb, Michael Neise, Klaus Mathias, and Horst J. Jaeger
- Subjects
Male ,medicine.medical_specialty ,Pacemaker, Artificial ,medicine.medical_treatment ,Electrocardiography ,Internal medicine ,medicine ,Bradycardia ,Fluoroscopy ,Humans ,Lead (electronics) ,Tricuspid valve ,medicine.diagnostic_test ,business.industry ,Mitral valve replacement ,Cardiac Pacing, Artificial ,Heart ,General Medicine ,Middle Aged ,Pacemaker leads ,Surgery ,Electrodes, Implanted ,Lateral chest ,medicine.anatomical_structure ,Cardiology ,Equipment Failure ,Permanent pacemaker ,Cardiology and Cardiovascular Medicine ,Chest radiograph ,business - Abstract
A 63-year-old male received a transvenous temporary pacemaker for bradyarrhythmia following mitral valve replacement and tricuspid valve annuloplasty. A transvenous permanent pacemaker was implanted the following day due to persistence of the bradyarrythmia and pacemaker dependency of the patient. Later the same day during removal of the temporary pacing electrode the permanent pacing lead was dislodged and had to be operatively repositioned. To avoid this complication, the position of pacemaker leads should be checked postoperatively with a frontal and lateral chest radiograph, and fluoroscopy should be used during removal of a temporary lead.
- Published
- 1994
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