41 results on '"Horne, Christopher R."'
Search Results
2. CaMKK2 as an emerging treatment target for bipolar disorder
3. Phosphorylation-dependent pseudokinase domain dimerization drives full-length MLKL oligomerization
4. A common human MLKL polymorphism confers resistance to negative regulation by phosphorylation
5. Unusual PDGFRB fusion reveals novel mechanism of kinase activation in Ph-like B-ALL
6. TRAPs: the ‘elevator-with-an-operator’ mechanism
7. Membrane permeabilization is mediated by distinct epitopes in mouse and human orthologs of the necroptosis effector, MLKL
8. Human RIPK3 C-lobe phosphorylation is essential for necroptotic signaling
9. N-acetylmannosamine-6-phosphate 2-epimerase uses a novel substrate-assisted mechanism to catalyze amino sugar epimerization
10. A toolbox for imaging RIPK1, RIPK3, and MLKL in mouse and human cells
11. Multi-wavelength analytical ultracentrifugation as a tool to characterise protein–DNA interactions in solution
12. Mechanism of NanR gene repression and allosteric induction of bacterial sialic acid metabolism
13. Conformational interconversion of MLKL and disengagement from RIPK3 precede cell death by necroptosis
14. Granulovirus PK-1 kinase activity relies on a side-to-side dimerization mode centered on the regulatory αC helix
15. Regulation of the EphA2 receptor intracellular region by phosphomimetic negative charges in the kinase-SAM linker
16. Human RIPK3 maintains MLKL in an inactive conformation prior to cell death by necroptosis
17. “Just a spoonful of sugar...”: import of sialic acid across bacterial cell membranes
18. The web of death: the expanding complexity of necroptotic signaling
19. Nanobodies identify an activated state of the TRIB2 pseudokinase
20. A common humanMLKLpolymorphism confers resistance to negative regulation by phosphorylation
21. Giving Children Space: A Phenomenological Exploration of Student Experiences in Space Science Inquiry
22. Nanobodies identify an activated state of the TRIB2 pseudokinase
23. Using cryo-EM to uncover mechanisms of bacterial transcriptional regulation
24. The intracellular domains of the EphB6 and EphA10 receptor tyrosine pseudokinases function as dynamic signalling hubs
25. SMCHD1's ubiquitin-like domain is required for N-terminal dimerization and chromatin localization
26. Membrane permeabilization is mediated by distinct epitopes in mouse and human orthologs of the necroptosis effector, MLKL
27. For Whom the Bell Tolls: The Structure of the Dead Kinase, IRAK3
28. Modifying the resolving cysteine affects the structure and hydrogen peroxide reactivity of peroxiredoxin 2
29. Mechanism of NanR gene repression and allosteric induction of bacterial sialic acid metabolism
30. A toolbox for imaging RIPK1, RIPK3 and MLKL in mouse and human cells
31. Structure–Function Studies of the Antibiotic Target l,l-Diaminopimelate Aminotransferase from Verrucomicrobium spinosum Reveal an Unusual Oligomeric Structure
32. On the structure and function of Escherichia coli YjhC: An oxidoreductase involved in bacterial sialic acid metabolism
33. Mechanism of NanR gene repression and allosteric induction of bacterial sialic acid metabolism
34. Cover Image, Volume 88, Issue 5
35. The basis for non-canonical ROK family function in the N-acetylmannosamine kinase from the pathogen Staphylococcus aureus
36. Functional and solution structure studies of amino sugar deacetylase and deaminase enzymes from Staphylococcus aureus
37. “Just a spoonful of sugar...”: import of sialic acid across bacterial cell membranes
38. Structure–Function Studies of the Antibiotic Target l,l-Diaminopimelate Aminotransferase from Verrucomicrobium spinosumReveal an Unusual Oligomeric Structure
39. Functional and solution structure studies of amino sugar deacetylase and deaminase enzymes from Staphylococcus aureus.
40. Inhibitors identify an auxiliary role for mTOR signalling in necroptosis execution downstream of MLKL activation.
41. Large Scale Genomic Investigation of Pediatric Cholestasis Reveals a Novel Hepatorenal Ciliopathy Caused by PSKH1 Mutations.
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