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5 results on '"Hoogen, Frank J.A. van den"'

3. The value of computed tomography scan versus an explorative surgical approach for removal of squamous cell carcinoma of the posterior pharyngeal wall

Author

Hoogen, Frank J.A. van den, Balm, Alfons J.M., Hilgers, Frans J.M., Tan, I. Bing, and Koops, W.

Subjects
CT imaging -- Evaluation, Squamous cell carcinoma, Pharynx, Throat cancer, Health
Abstract

BACKGROUND: The prevertebral fascia plays a key role in surgery of posterior pharyngeal wall tumors. Invasion of the prevertebral muscles determines the irresectability of the tumor and accurate diagnosis of invasion posteriorly is a prerequisite for major ablative surgery. METHODS: A retrospective study was performed to define the value of CT scanning versus open neck exploration with regard to the resectability of posterior pharyngeal wall carcinoma. The predictive value of preoperative CT scans was assessed and compared with the outcome of open neck exploration and resectability of the primary tumor, using the final histopathology report as a gold standard. RESULTS: Nineteen patients with 20 tumors were included in this study. Overall the CT scan was correct concerning prevertebral muscle status in 4 out of 20 (20%), whereas open neck exploration was correct in 18 tumors (90%). CONCLUSION: The predictive value of a suspicious CT scan in determining prevertebral muscle invasion is extremely low in this study. Open neck exploration seems to be superior for determining resectability of posterior wall carcinoma.

Published
1996

5. Salivation in healthy schoolchildren

Author

Rotteveel, Liselotte J.C., Jongerius, Peter H., Limbeek, Jacques van, and Hoogen, Frank J.A. van den

Subjects
*CARE of children with disabilities, *SALIVA, *PAROTID glands, *SCHOOL children
Abstract

Objective: To obtain reference data on the unstimulated salivary flow rate in healthy 6–11-year-old boys and girls, for use in the treatment of drooling in mentally and physically handicapped children. Methods: Under standard conditions unstimulated saliva was collected from 62 healthy children using the swab method. Flow rate was determined by calculating the increase in weight of cotton rolls placed in the mouth for 5 min. The influence of the variables age, gender and type of gland were evaluated. Results: No significant difference was found between the flow rate in boys and girls or between the children in this age window. The swab method showed good reproducibility. The right and left parotid glands had equal flow rates of 0.15 ml/min. The flow rate in the floor of the mouth secreted by the submandibular and sublingual glands was 0.32 ml/min. Conclusions: In healthy children of 6–11 years, age and gender did not influence the salivary flow rate and therefore do not have to be taken in consideration when measuring salivary flow rate. The swab method was reliable, easy to carry out and well-tolerated by the group of schoolchildren. [Copyright &y& Elsevier]

Published
2004
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