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Diabetes is a progressive and severe chronic metabolic disease. It is a major public health problem, responsible for a high morbidity and mortality rate in the world and in Morocco. Our study involves 50 patients with type 2 diabetes recruited at the Hay Ennahda II Extention III Non-Communicable Disease Medical Center in Rabat. This is a descriptive and analytical observational study, the purpose of which is to assess the quality of life of Moroccan type 2 diabetic patients by means of a generic questionnaire "SF-12" and a specific questionnaire for diabetes "Diabetes-39". The results showed that diabetes negatively affects the quality of life of diabetic patients and established that the factors associated with their quality of life are multiple: factors related to socio-demographic characteristics (gender, ethnicity and marital status), comorbidities (hypertension and dyslipidemia), related to the pathology itself (obesity) and its chronic degenerative complications (diabetic neuropathy and obliterative arteriopathy of the lower limbs). Unlike the literature, some socio-economic characteristics (age, level of education, professional activity), others related to diabetes (age of diabetes and glycemic control) and therapeutic management do not affect quality of life in our study, this can be explained by the size of our sample. This preliminary study is a pilot study that introduces the issue of the quality of life of people with diabetes in Rabat. It will be continued to obtain a larger sample, in order to better study the peculiarities of the Moroccan patients in this field.