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Reconfigurable metamaterials require constituent nanostructures to demonstrate switching of shapes with external stimuli. Yet, a longstanding challenge is in overcoming stiction caused by van der Waals forces in the deformed configuration, which impedes shape recovery. Here, we introduce stiff shape memory polymers. This designer material has a storage modulus of ∼5.2 GPa at room temperature and ∼90 MPa in the rubbery state at 150 °C, 1 order of magnitude higher than those in previous reports. Nanopillars with diameters of ∼400 nm and an aspect ratio as high as ∼10 were printed by two-photon lithography. Experimentally, we observe shape recovery as collapsed and touching structures overcome stiction to stand back up. We develop a theoretical model to explain the recoverability of these sub-micrometer structures. Reconfigurable structural color prints with a resolution of 21150 dots per inch and holograms are demonstrated, indicating potential applications of the stiff shape memory polymers in high-resolution reconfigurable nanophotonics.

Trigger-responsive surfaces with multiple surface properties have wide-ranging application potential from surfaces with trigger-responsive fluid flow to cell culture to optical effects; such surfaces can be achieved through surface morphological changes. Although multiple shape-memory effects are successful in bulk polymers, there is limited programing and recovery of multiple surface memories due to the challenges in fabricating multiple surface topographies with good controllability. Here, we report the synergy between the polymer blend formulation and the thermal nanoimprinting process to achieve multiple microtopography memories. A series of immiscible blends consisting of poly(caprolactone) (PCL) and polyethylene (PE) with distinct thermal transitions governed by distinct crystallization events were augmented with improved elasticity through preferential cross-linking in the polymer blend. The effect of preferential cross-linking by dicumyl peroxide on the elastic property of the PCL/PE has been found to be nonlinearly dependent on the blend composition. This approach enabled triple and quadruple surface pattern fixity and recovery in nanoimprinted PCL/PE blends. Specifically, we demonstrated the recovery of a micropillar structure (diameter: 20 μm and height: 10 μm) from a hierarchical micrograting topography (width: 2 μm and height: 2 μm) when exposed to a thermal stimulus at 60 °C for 180 s. Furthermore, we also demonstrated the recovery of a deformed micrograting followed by a secondary recovery of the micropillar structure.

Superhydrophobic surfaces have been largely achieved through various surface topographies. Both empirical and numerical simulations have been reported to help understand and design superhydrophobic surfaces. Many such successful surfaces have also been achieved using bioinspired and biomimetic designs. Despite this, identifying the right surface texture to meet the requirements of specific applications is not a straightforward task. Here, we report a hybrid approach that includes experimental methods, numerical simulations, and machine learning (ML) algorithms to create design maps for superhydrophobic polymer topographies. Two design objectives to investigate superhydrophobic properties were the maximum water contact angle (WCA) and Laplace pressure. The design parameters were the geometries of an isotropic pillar structure in micrometer and sub-micrometer length scales. The finite element method (FEM) was validated by the experimental data and employed to generate a labeled dataset for ML training. Artificial neural network (ANN) models were then trained on the labeled database for the topographic parameters (width W, height H, and pitch P) with the corresponding WCA and Laplace pressure. The ANN models yielded a series of nonlinear relationships between the topographic design parameters and the WCA and Laplace pressure and substantial differences between the micrometer and sub-micrometer length scales. Design maps that span the topography design parameters provide optimal design or tradeoff parameters. This research demonstrates the potential of ANN as a rapid design tool for surface topography exploration.

Transient electronics is an emerging class of electronics that has attracted a lot of attention because of its potential as an environmental-friendly alternative to the existing end-of-life product disposal or treatments. However, the controlled degradation of transient electronics under environmentally benign conditions remains a challenge. In this work, the tunable degradation of transient electronics including passive resistor devices and active memory devices was realized by photodegradable thin polymer films comprising fullerene derivatives, [6,6]-phenyl-C61-butyric acid methyl esters (PCBM). The photodegradation of polymer:PCBM under an aqueous environment is triggered by ultraviolet (UV) light. Experimental results demonstrate that the addition of PCBM in commodity polymers, including but not limited to polystyrene, results in a catalytic effect on polymer photodegradation when triggered by UV light. The degradation mechanism of transient electronics is ascribed to the photodegradation of polymer:PCBM encapsulation layers caused by the synergistic effect between UV and water exposure. The polymer:PCBM encapsulation system presented herein offers a simple way to achieve the realization of light-triggered device degradation for bioapplication and expands the material options for tailorable degradation of transient electronics.

The challenge in achieving extreme wetting (

To achieve the ambitious targets set out in the Paris Agreement, technological innovations that will advance direct air capture technology are needed. The grand challenge to increase total amount of CO2 capture directly from ambient air may be achieved by a direct air capture platform that can be implemented widely in urban spaces. In this work, we present a pioneering passive and distributed direct air capture (DAC) approach that leverages on the highly adaptable form factor of a carbon capture composite (C3) film. Through a synergy between a highly flexible form factor and surface texture engineering on the C3 film, effective passive CO2 capture has been demonstrated. The carbon capture performance (capacity, kinetics) of micro-textured C3 films were evaluated using an in-house controlled chamber as well as in a field study (e.g., bus-stop). Based on the findings from this study, it was observed that the micro-textured C3 films effectively improve direct air capture at a relatively low CO2 concentration. Additionally, field tests of the C3 films at a bus-stop shows a reduction in the number of CO2 surges associated with the arrival of buses. Together these findings demonstrated for the first time the potential to integrate the versatile and regenerable C3 films with existing infrastructure for distributed direct air capture in urban spaces.

Micro- and nanoscale surface topographies that give rise to superhydrophobic surfaces have been achieved mostly on 2-dimensional planar objects. Increasing interests in superhydrophobic surfaces on consumer products, optics, and biomedical devices demand topographic patterning on free-form nonplanar surfaces via a high throughput manufacturing process such as injection molding. However, successes in high-resolution (submicrometer) injection molding have been limited to flat and planar objects. A challenge associated with achieving submicrometer surface resolution on a 3-dimensional curved object lies in the control of the replication process in a multiscale mold cavity and the nonuniform temperature and pressure distribution over a macroscopically curved mold insert. Here, a two-step simulation approach is employed to investigate the replication of polymer in the macroscopic and submicrometer cavities. Both simulation and experimental data revealed the effects of holding pressure, mold temperature, and ma...

Controlling polymer film solubility is of fundamental and practical interest and is typically achieved by synthetically modifying the polymer structure to insert reactive groups. Here, we demonstrate that the addition of fullerenes or its derivatives (C60 or phenyl-C61-butyric acid methyl ester, PCBM) to polymers, followed by ultraviolet (UV) illumination can change the film solubility. Contrary to most synthetic polymers, which dissolve in organic solvents but not in water, the fullerene-doped polymer films (such as polystyrene) can dissolve in water yet remain stable in organic solvents. This photoswitchable solubility effect is not observed in either film constituents individually and is derived from a synergy of photochemistries. First, polymer photooxidation generates macroradicals which cross-link with radical-scavenging PCBM, thereby contributing to the films' insolubility in organic solvents. Second, light exposure enhances polymer photooxidation in the presence of PCBM via the singlet oxygen pathway. This results in polymer backbone scission and formation of photooxidized products which can form hydrogen bonds with water, both contributing to water solubility. Nevertheless, the illuminated doped polymer thin films are mechanically robust, exhibiting significantly increased modulus and density compared to their pristine counterpart, such that they can remain intact even upon sonication in conventional organic solvents. We further demonstrate the application of this solubility-switching effect in dual tone photolithography, via a facile, economical, and environmentally benign solution-processing route made possible by the photoactive nature of polymer-PCBM thin films.

Four-dimensional (4D) printing of shape memory polymer (SMP) imparts time responsive properties to 3D structures. Here, we explore 4D printing of a SMP in the submicron length scale, extending its applications to nanophononics. We report a new SMP photoresist based on Vero Clear achieving print features at a resolution of ~300 nm half pitch using two-photon polymerization lithography (TPL). Prints consisting of grids with size-tunable multi-colours enabled the study of shape memory effects to achieve large visual shifts through nanoscale structure deformation. As the nanostructures are flattened, the colours and printed information become invisible. Remarkably, the shape memory effect recovers the original surface morphology of the nanostructures along with its structural colour within seconds of heating above its glass transition temperature. The high-resolution printing and excellent reversibility in both microtopography and optical properties promises a platform for temperature-sensitive labels, information hiding for anti-counterfeiting, and tunable photonic devices., Four-dimensional (4D) printing of shape memory polymer (SMP) imparts time responsive properties to 3D structures. Here, the authors explore 4D printing of a SMP in the submicron length scale, extending its applications to nanophononics.

Nanoacoustic fields are a promising method for particle actuation at the nanoscale, though THz frequencies are typically required to create nanoscale wavelengths. In this work, the generation of robust nanoscale force gradients is demonstrated using MHz driving frequencies via acoustic-structure interactions. A structured elastic layer at the interface between a microfluidic channel and a traveling surface acoustic wave (SAW) device results in submicron acoustic traps, each of which can trap individual submicron particles. The acoustically driven deformation of nanocavities gives rise to time-averaged acoustic fields which direct suspended particles toward, and trap them within, the nanocavities. The use of SAWs permits massively multiplexed particle manipulation with deterministic patterning at the single-particle level. In this work, 300 nm diameter particles are acoustically trapped in 500 nm diameter cavities using traveling SAWs with wavelengths in the range of 20-80 µm with one particle per cavity. On-demand generation of nanoscale acoustic force gradients has wide applications in nanoparticle manipulation, including bioparticle enrichment and enhanced catalytic reactions for industrial applications.

Many technologies are increasingly dependent on the development of membranes with highly precise pore size and spatial order. While mold-based lithographic techniques are adopted for the fabrication of such ordered porous membranes, their transition toward large-scale fabrication remains challenging because of manual and laborious process requirements. To facilitate the transition from batch to continuous membrane production, a novel roll-to-roll (R2R) process was designed based on an established capillary-driven molding technique. Establishing conformal contact between patterned mold and web support and the capillary filling of the UV-curable resin forms the basis of the molding process, which is automated by the R2R platform with precise positioning and reproducible contact force. This results in the in situ formation of residual-layer-free membranes without additional complex, expensive etching steps and, more importantly, with high throughput up to 3000 mm2/min. The versatile process allows the combin...

Summary Background Transmission of microbes in the hospital environment occurs frequently through human interactions with high-touch surfaces such as patient beds and over-bed tables. Although stringent cleaning routines are implemented as a preventive measure to minimize transmission of microbes, it is desirable to have high-touch surfaces made of antimicrobial materials. Physical texturing of solid surfaces offers a non-bactericidal approach to control the colonization of such surfaces by microbes. Aim To investigate the efficacy of micro-textured polycarbonate films in reducing bacterial load on over-bed tables in a hospital ward. Methods Two different micro-patterns were fabricated on polycarbonate film via a thermal imprinting method. Micro-textured films were then mounted on patient over-bed tables in a general hospital ward and the bacterial load monitored over 24 h. Total colony counts, which represented on-specific bacterial loading, and meticillin-resistant Staphylococcus aureus counts were monitored at each time-point. Findings Over a period of 24 h, both micro-textured surfaces showed consistently lower bacterial load as compared to the unpatterned polycarbonate and the bare over-bed table laminate. This study supports the findings of earlier laboratory-scale studies that microscale physical texturing can reduce bacterial colonization on a solid surface. Conclusion Results of the current study suggest that micro-textured surfaces could provide a viable method for reducing microbial contamination of high-touch surfaces in hospitals.

Plane-to-plane transitioning has been a significant challenge for climbing robots. To accomplish this, additional actuator or robot module is usually required which significantly increases both size and weight of the robot. This paper presents a two-wheg miniature climbing robot with a novel passive vertical tail component which results in robust transitioning capabilities. The design decision was derived from an indepth force analysis of the climbing robot while performing the transition. The theoretical analysis is verified through a working prototype with robust transitioning capabilities whose performance follows closely the analytical prediction. The climbing robot is able to climb any slope angles, 4-way internal transitions, and 4-way external transitions. This work contributes to the understanding and advancement of the transitioning capabilities and the design of a simple climbing robot, which expands the possibilities of scaling down miniature climbing robot further.

This paper presents the design, modeling, and analysis of the force behavior acting on a wheel-legs (whegs) type robot which utilizes bilayer dry adhesives for wall-climbing. The motion of the robot is modeled as a slider-crank mechanism to obtain the dynamic parameters of the robot during movement. The required forces and moment to maintain equilibrium as the robot is in motion is then extensively analyzed and discussed. Following the analysis, fundamental measures to attain an operative climbing robot, such as adhesive requirement and torque specification, are then identified. The outcomes of the analysis are verified through experiments and working prototypes that are in good agreement with the design guidelines.

We report a dual-stage photocrosslinked polymer network based on sequential ultraviolet (UV)-triggered radical polymerization and thermally activated etherification, applicable to the fabrication of tailorable and programmable high-resolution structures. The first stage involves photoinitiated polymerization of monomer and crosslinker to obtain an intermediate polymer network. As such, sophisticated two-dimensional (2D) and micro-scale three-dimensional (3D) structures can be made by using UV-based advanced manufacturing technologies. These complex structures can then be readily programmed into other desired, permanent shapes, in the second stage, via thermally triggered etherification which results in a highly crosslinked, robust polymer network. The intermediate network (Stage I) is characterized to have a Young’s modulus ranging from 342 to 1146 MPa and a glass transition temperature from 52 °C to 83 °C, depending on the concentration of crosslinker. The same material attains a glass transition temperature ranging from 67 °C to ~105 °C and a Young’s modulus of up to 1607 MPa after the subsequent heating process (Stage II). Originally 3D printed 2D structures can be further programmed into rigid, permanent 2.5/3D ones. Micropatterns fabricated from intrinsically hydrophilic dual-stage crosslinked photopolymers through soft lithography show superhydrophobicity, and can subsequently be molded with different curvatures for practical applications.

Direct imprinting of metals is predominantly achieved by using polydimethylsiloxane (PDMS) molds to pattern metal nanoparticles and subsequently melting them to form continuous structures. Although such a combination can successfully imprint metals, the yield and reproducibility are usually low when sub-100 nm features over large areas are desired. In this work, we demonstrate a simple method involving the addition of a cross-linker ethylene glycol dimethacrylate (EDMA) to a palladium metal precursor, and its in situ free radical polymerization during imprinting, which not only dramatically increases the yield to ∼100% but also enables high reproducibility. Palladium mercaptide resist was formed by dissolving acetoxy(benzylthio)palladium, EDMA and azobis-(isobutyronitrile) in an organic solvent mixture. The resist underwent polymerization when imprinted using a silicon mold at 120 °C with pressures as low as 30 bar. Polymerization rigidly shapes the imprinted patterns, traps the metal atoms, reduces the surface energy and strengthens the structures, thereby giving ∼100% yield after demolding. Heat-treatment of the imprinted structures at 330 °C resulted in the loss of organics and their subsequent shrinkage without the loss of integrity or aspect ratio and converted them to palladium nanostructures as small as ∼35 nm wide, over areas >1 cm × 1 cm. With suitable precursors, our technique can potentially be extended to pattern noble metals such as platinum, gold and silver.

A study is presented on the transfer of low surface tension reactive monomers such as monomethacryloxypropyl-terminated poly-dimtheylsiloxane (mPDMS) from a host bi-layer hard-PDMS (h-PDMS)/PDMS silicone mold to cured resin coated web surfaces in situ during UV roll-to-roll nanoimprint lithography. Here the bi-layer silicone mold plays a dual role as both a lithographic template as well as a release agent transfer vehicle, accomplishing both tasks without additional in-line processing steps. This paper is thus an early investigation into large area multi-functional silicone stamps designed especially for production of low surface energy polymer resin molds via roll-to-roll processing.

Multi-material fused filament printing (FFP) of conductive and dielectric materials has tremendous potential in the co-fabrication of embedded electronics, allowing for increasing freedoms in part design while seamlessly integrating electrical components to mechanical structures. However, co-fabrication of 3D embedded conductive structures have proven challenging, due to poor electrical conductivity of printed conductive structures, and geometrical restrictions of printed conductive structures bound by material properties. Here, we introduce a highly conductive low density polyethylene (LDPE) composite filled with copper particles and Sn95Ag4Cu1. At metal filler content of 35 % vol, the electrical conductivity of the composite achieves 3.3 × 104 S/m with a Young’s modulus of 7.2 GPa. Through a combination of inert and reducing gas environment, thermo-oxidation of the conductive composite has been minimized. Additionally, the electrical conductivity of the printed composite has been correlated to the morphology of the print. Under optimized printing parameters, the fuse-filament printed conductive structure retained 55 % (of 1.05 × 104 S/m) of its electrical conductivity after printing. A series of mechanically stable suspended bridge structure has been printed using the LDPE-Cu-Sn95Ag4Cu1 composite. We further demonstrate compressive sensing of two types of embedded and suspended structures: toroidal disk and interdigitated fingers. These designs have been printed without using support structure. This work shows the potential in co-fabrication of electrically functional components in a dielectric structure with high degree of geometrical freedom.

This paper presents the design and fabrication of ORION-II for autonomous Intelligence, Surveillance and Reconnaissance (ISR). ORION-II is a miniature climbing robot equipped with all the necessary electronic components to achieve ISR tasks. It consists of a robot chassis (tail) carrying the electronics and two DC motors each driving a wheel-leg (wheg) with four “flaps” equipped with bilayer compliant tapes. Two types of tapes are used for attachment of ORION-II: bilayer PDMS/foam and bilayer micro-suction/foam. The two types of tapes are tested on different climbing surfaces, and the climbing performance is reported. ORION-II could climb rougher surfaces when using the PDMS/foam tape, and perform internal climbing transitions when using the micro-suction/foam tape. The total weight of ORION-II is 153.18 g as compared with 71.5 g of our previous version ORION-I.

This paper presents the design, modeling, and analysis of the force behavior acting on a wheel-legs (whegs) type robot which utilizes bilayer dry adhesives for wall-climbing. The motion of the robot is modeled as a slider-crank mechanism to obtain the dynamic parameters of the robot during movement. The required forces and moment to maintain equilibrium as the robot is in motion is then extensively analyzed and discussed. Following the analysis, fundamental measures to attain an operative climbing robot, such as adhesive requirement and torque specification, are then identified. The outcomes of the analysis are verified through experiments and working prototypes that are in good agreement with the design guidelines.

Reduced graphene oxide (rGO) has been fabricated into a microelectrode array (MEA) using a modified nanoimprint lithography (NIL) technique. Through a modified NIL process, the rGO MEA was fabricated by a self-alignment of conducting Indium Tin Oxide (ITO) and rGO layer without etching of the rGO layer. The rGO MEA consists of an array of 10μm circular disks and microelectrode signature has been found at a pitch spacing of 60μm. The rGO MEA shows a sensitivity of 1.91nAμm(-1) to dopamine (DA) without the use of mediators or functionalization of the reduced graphene oxide (rGO) active layer. The performance of rGO MEA remains stable when tested under highly resistive media using a continuous flow set up, as well as when subjecting it to mechanical stress. The successful demonstration of NIL for fabricating rGO microelectrodes on flexible substrate presents a route for the large scale fabrication of highly sensitive, flexible and thin biosensing platform.

Miniaturization of robotic systems has led to a demand for an alternative adhesive for use as the footpad of robots, with primary requirements of minimizing energy expenditure and satisfying performance and operational scenarios such as surveillance and reconnaissance. Inspired by nature, the dry adhesive concept as seen in climbing lizards such as the gecko has drawn significant interest from researchers. Adhesion in geckos is attributed to micro/nano fibrils found on its feet that rely on van der Waals forces to adhere to a surface, hence the terminology of dry adhesive. While immense progress has been made in the design and fabrication of multiscale hierarchical adhesive structures, the robustness, durability and endurance (ability to adhere to surfaces for an extended period of time) of gecko-foot mimetic dry adhesives still lags behind their biological counterparts. In this review article, we highlight the design considerations for the development of robust and durable bio-inspired synthetic adhesives. Current challenges and future directions are also highlighted for the design and development of robust and durable dry adhesive structures.

The unusual ability of geckos to climb vertical walls underlies a unique combination of a hierarchical structural design and a stiffer material composition. While a dense array of microscopic hierarchical structures enables the gecko toe pads to adhere to various surfaces, a stiffer material (β-keratin) composition enables them to maintain reliable adhesion over innumerable cycles. This unique strategy has been seldom implemented in engineered dry adhesives because fabrication of high-aspect-ratio hierarchical structures using a stiffer polymer is challenging. Herein, we report the fabrication of high-aspect-ratio hierarchical arrays on flexible polycarbonate sheets (stiffness comparable to that of β-keratin) by a sacrificial-layer-mediated nanoimprinting technique. Dry-adhesive films comprising the hierarchical arrays showed a formidable shear adhesion of 11.91 ± 0.43 N/cm2. Cyclic adhesion tests also showed that the shear adhesion of the adhesive films reduced by only about 20% after 50 cycles and remained nearly constant until about 200 cycles. Most importantly, the high-aspect-ratio hierarchical arrays were integrated onto the feet of a miniature robot and the locomotion on a 30° inclined surface was demonstrated.

Surface wetting on the textured surface is classically explained by the theories of Cassie-Baxter or Wenzel. However, in recent years, an increasing number of complex surface topographies with superhydrophobic properties have been achieved without prediction or simulation using these theories. One example is biomimetic surfaces. In many instances, theories were used to explain surface properties found in nature but have not led to or predicted the complex topographies. Although new wetting theories continue to emerge, there is not yet a set of design rules to guide the selection of surface topographies to achieve superhydrophobicity. By grouping known surface topographies into common geometrical descriptions and length scale, this paper suggests a set of surface topography classifications to provide selection guidelines for engineering superhydrophobic surfaces. Two key outcomes emerged from the design analysis: first, categorization of frequently reported surface patterns shows that there exists a set of commonly used descriptions among diverse designs; second, the degree of hydrophobicity improvement within a class of topography design can be used to predict the limit of improvement in superhydrophobicity for a given material. The presentation of topography descriptors by categories of design and performance may serve as a prologue to an eventually complete set of design guidelines for superhydrophobic performance. Refereed/Peer-reviewed

To reproduce a complex and functional tissue, it is crucial to provide a biomimetic cellular microenvironment that not only incorporates biochemical cues, but also physical features including the nano-topographical patterning, for cell/matrix interaction. We developed spatially-controlled nano-topography in the form of nano-pillar, nano-hole and nano-grill on polycaprolactone surface via thermal nanoimprinting. The effects of chondroitin sulfate-coated nano-topographies on cell characteristics and chondrogenic differentiation of human mesenchymal stem cell (MSC) were investigated. Our results show that various nano-topographical patterns triggered changes in MSC morphology and cytoskeletal structure, affecting cell aggregation and differentiation. Compared to non-patterned surface, nano-pillar and nano-hole topography enhanced MSC chondrogenesis and facilitated hyaline cartilage formation. MSCs experienced delayed chondrogenesis on nano-grill topography and were induced to fibro/superficial zone cartilage formation. This study demonstrates the sensitivity of MSC differentiation to surface nano-topography and highlights the importance of incorporating topographical design in scaffolds for cartilage tissue engineering. From the clinical editor: These authors have developed spatially-controlled nano-topography in the form of nano-pillar, nano-hole and nano-grill on polycaprolactone surface via thermal nanoimprinting, and the effects of chondroitin sulfate-coated nano-topographies on cell characteristics and chondrogenic differentiation of human mesenchymal stem cells (MSC) were investigated. It has been concluded that MSC differentiation is sensitive to surface nano-topography, and certain nano-imprinted surfaces are more useful than others for cartilage tissue engineering.

The super hydrophobic, self-cleaning properties of natural species derive from the fine hierarchical topography evolved on their surfaces. Hierarchical architectures which are function-mimetic of the lotus leaf are here described and created from multi-scale hierarchical assembled templates. The first level of hierarchy was a micromachined dome structure template and the second level of hierarchy was added by layering a thin nanoporous membrane such as porous anodized alumina or an ion track etch membrane. The assembled templates were nanoimprinted by a single step process on thermoplastic films. The wetting angle of the surfaces reached a value of 160° and the self-cleaning behavior was observed. The superhydrophobic behavior remained over 1 year after fabrication, which demonstrates the stability of these polymeric self-cleaning topographies. © 2014 Wiley Periodicals, Inc. J. Polym. Sci. Part B. Polym. Phys. 2014, 52, 603–609

Large size and high quality graphene grown by chemical vapour deposition (CVD) has been fabricated into an array of discrete graphene sheets with well-defined sizes and shapes. A fabrication process based on nanoimprint lithography has been developed to achieve shape tunability with sizes ranging from micrometer to nanometer. The technique preserves the quality of the CVD grown graphene and offers the versatility of transferring the graphene array onto any rigid or flexible substrate. The process is then expanded to fabricating a graphene based microelectrode array whose performance is demonstrated in the real time sensing of peroxidase excreted by breast cancer cells. The device displayed a linear working range of 0.01–25 mM and a sensitivity of 8.8 mA mol−1.

Rose petal mimetic surfaces with ultrahigh water pinning forces have been fabricated via nanoimprinting process onto three different polymer films. Water pinning forces ranging from 104 to 690 μN are obtained on free-standing polycarbonate films with imprinted nanostructures. Through a systematic variation of the surface structures, this study provides experimental evidence that an ultrahigh water pinning force can be achieved by combining two surface topographical designs: (1) conical- or parabolic-shaped nanoprotrusions and (2) isotropic and continuous nanoprotrusions. These design criteria ensure that a continuous solid-liquid contact line is achieved and provide a rule-of-thumb to engineer surfaces with tunable water pinning forces. The ultrahigh water pinning film is further demonstrated to mitigate the "coffee ring" effect, a phenomenon associated with nonuniform deposition from a drying solute-laden liquid droplet.