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574 results on '"Hong, Linda"'

1. Validation of Patient-Reported Outcomes in Patients With Nonmetastatic Breast Cancer Receiving Comprehensive Nodal Irradiation in the RadComp Trial

Author

Godette, Karen D., Patel, Sagar, Langen, Katja M., Zielan, Ryan R., DeBlois, David, Pang, Dalong, Rudra, Sonali, Benhabib, Sidi, Chawla, Ashish, Chen, Kuanling, Dadkhah, Hossein, Majithia, Lonika, Rao, Avani D., Stephenson, Lisa, Wang, Peng, Croog, Victoria J., Li, Heng, Smith, Karen, Stinson, Susan, Walker, Amanda J., Devisetty, Kiran, Hyde, Christian, Depauw, Nicholas, Godishala, Anuradha, Ho, Alice, Paganetti, Harald, Soto, Daniel, Suero-Abreu, Giselle, Taghian, Alphonse G., Corbin, Kimberly S., Halyard, Michele Y., Jackson, Amanda, Liang, Xiaoying, Manke, Heather, McGee, Lisa A., Pafundi, Deanna H., Remmes, Nicholas B., Shumway, Dean A., Yan, Elizabeth S., Bakhoum, Samuel F., Barron, David A., Bernstein, Michael, Cuaron, John J., Dover, Laura, Gelblum, Daphna Y., Gilbo, Philip, Gewanter, Richard M., Guttman, David M., Hong, Linda, Khan, Atif, LaPlant, Quincey, Mann, Justin, McCormick, Beryl, Mueller, Boris A., Mychalczak, Borys, Parikh, Dhwani, Powell, Simon N., Romesser, Paul B., Roth O'Brien, Diana, Schupak, Karen D., Shepherd, Annemarie F., Xu, Amy, Yu, Anthony, Zinovoy, Melissa, Bennouna, Jaafar, Fagundes, Marcio, Panoff, Joseph, Amelia Rodrigues, Maria, Yu, Jen, Lee, Choonsik, Chen, Chin-Cheng, Choi, J. Isabelle, Lin, Haibo, Akthar, Adil S., Akhter, Nausheen, Mihalcik, Stephen A., Pankuch, Mark, Parhar, Preeti K., Stutz, Michael D., Thukral, Arpi D., Mah, Dennis, Tsai, Henry K., Paulus, Rebecca, Haffty, Bruce G., Goyal, Sharad, Yue, Ning J., Sturgeon, Jared D., Wilkinson, J. Ben, Boggs, D. Hunter, Cardan, Rex A., Dalton, Allison, McDonald, Andrew, Prior, Fred, Mayadev, Jyoti S., Moiseenko, Vitali, Narezkina, Anya, Phreaner, Nicholas, Rash, Dominique, Seibert, Tyler, Yashar, Catheryn, Daugherty, Emily C., Mascia, Anthony, Medek, Sara A., Meier, Teresa, Bradley, Julie A., Lockney, Natalie, Mailhot, Raymond B., Mendenhall, Nancy, Rutenberg, Michael, Harris, Eleanor E., Lyons, Janice, Hong, Jack J., Kunaprayoon, Dan K., McAvoy, Sarah A., Manu Mysore, Nowak Choi, Kamila A., Patel, Akshar N., Vyfhuis, Melissa A.L., Wilson, Joelle, Algan, Ozer, Chen, Yong, Henson, Christina E., Dvorak, Tomas, Willoughby, Twyla, Zeidan, Omar, Berman, Abigail T., Chen, Et-tsu, Dong, Lei, Driscoll, Amanda, Feigenberg, Steven J., Feriozzi, Ashley, Hencek, Carolyn, Kolker, James D., Konski, Andre A., Ky, Bonnie, Lin, Lilie L., Novick, Kristina L., Reza, Nosheen, Siegal, Ann Marie, Tabakha, Sara, Taunk, Neil K., Wilcox, Nicholas, Zou, Wei, Bhooshan, Neha, Croley, Richard, Weksberg, David C., Ahmad, Neelour, Hoffman, Karen E., Joyner, Melissa M., Mitchell, Melissa P., Poenisch, Falk, Smith, Benjamin D., Strom, Eric A., Vallabhaneni, Srilakshmi, Cheng, Richard, Kang, Kylie H., Kim, H. Katherine, Kim, Janice N., Wang, Waylene A., Wong, Tony, Bosch, Walter, Mitchell, Joshua, Straube, William, Zoberi, Imran, Balanescu, Dinu, Chen, Peter Y., Dilworth, Joshua T., Ding, Xuanfeng, Donisan, Teodora, Hamstra, Daniel A., Daniella Dang, Phuong, Katz, Stanford, Wang, Chiachien J., Terry Wu, Hahn, Elizabeth A., Pugh, Stephanie L., Lu, Hien L., Vela, Alyssa M., Gillespie, Erin F., Nichols, Elizabeth M., Wright, Jean L., MacDonald, Shannon M., Cahlon, Oren, Baas, Carole, Braunstein, Lior Z., Fang, L. Christine, Freedman, Gary M., Jimenez, Rachel B., Kesslering, Christy M., Mishra, Mark V., Mutter, Robert W., Ohri, Nisha, Rosen, Lane R., Urbanic, James J., Jagsi, Reshma, Mitchell, Sandra A., Bekelman, Justin E., and Cella, David

Published
2024
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13. Solvent Dependent Folding of an Amphiphilic Polyaramid

Author

Molliet, Angélique, primary, Doninelli, Samantha, additional, Hong, Linda, additional, Tran, Bettina, additional, Debas, Meron, additional, Salentinig, Stefan, additional, Kilbinger, Andreas F. M., additional, and Casalini, Tommaso, additional

Published
2023
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20. SLCO1B1 Variants and Urine Arsenic Metabolites in the Strong Heart Family Study

Author

Gribble, Matthew O, Voruganti, Venkata Saroja, Cropp, Cheryl D, Francesconi, Kevin A, Goessler, Walter, Umans, Jason G, Silbergeld, Ellen K, Laston, Sandra L, Haack, Karin, Kao, Wen Hong Linda, Fallin, Margaret Daniele, MacCluer, Jean W, Cole, Shelley A, and Navas-Acien, Ana

Subjects
Pharmacology and Pharmaceutical Sciences, Biomedical and Clinical Sciences, Clinical Research, Cardiovascular, Heart Disease, Genetics, Good Health and Well Being, Arsenic, Arsenicals, Biomarkers, Biotransformation, Cacodylic Acid, Cardiovascular Diseases, Female, Gene Frequency, Genetic Association Studies, Heterozygote, Homozygote, Humans, Indians, North American, Linear Models, Liver-Specific Organic Anion Transporter 1, Male, Organic Anion Transporters, Phenotype, Polymorphism, Single Nucleotide, Prospective Studies, United States, Water Pollutants, Chemical, American Indians, arsenic metabolism, arsenic species, SLCO1B1, OATPC, Strong Heart Study, Strong Heart Study., Toxicology, Pharmacology and pharmaceutical sciences
Abstract

Arsenic species patterns in urine are associated with risk for cancer and cardiovascular diseases. The organic anion transporter coded by the gene SLCO1B1 may transport arsenic species, but its association with arsenic metabolites in human urine has not yet been studied. The objective of this study is to evaluate associations of urine arsenic metabolites with variants in the candidate gene SLCO1B1 in adults from the Strong Heart Family Study. We estimated associations between % arsenic species biomarker traits and 5 single-nucleotide polymorphisms (SNPs) in the SLCO1B1 gene in 157 participants, assuming additive genetics. Linear regression models for each SNP accounted for kinships and were adjusted for sex, body mass index, and study center. The minor allele of rs1564370 was associated with lower %MMA (p = .0003) and higher %DMA (p = .0002), accounting for 8% of the variance for %MMA and 9% for %DMA. The rs1564370 minor allele homozygote frequency was 17% and the heterozygote frequency was 43%. The minor allele of rs2291075 was associated with lower %MMA (p = .0006) and higher %DMA (p = .0014), accounting for 7% of the variance for %MMA and 5% for %DMA. The frequency of rs2291075 minor allele homozygotes was 1% and of heterozygotes was 15%. Common variants in SLCO1B1 were associated with differences in arsenic metabolites in a preliminary candidate gene study. Replication of this finding in other populations and analyses with respect to disease outcomes are needed to determine whether this novel candidate gene is important for arsenic-associated disease risks.

Published
2013

21. Association of genetic variation with systolic and diastolic blood pressure among African Americans: the Candidate Gene Association Resource study

Author

Fox, Ervin R, Young, J Hunter, Li, Yali, Dreisbach, Albert W, Keating, Brendan J, Musani, Solomon K, Liu, Kiang, Morrison, Alanna C, Ganesh, Santhi, Kutlar, Abdullah, Ramachandran, Vasan S, Polak, Josef F, Fabsitz, Richard R, Dries, Daniel L, Farlow, Deborah N, Redline, Susan, Adeyemo, Adebowale, Hirschorn, Joel N, Sun, Yan V, Wyatt, Sharon B, Penman, Alan D, Palmas, Walter, Rotter, Jerome I, Townsend, Raymond R, Doumatey, Ayo P, Tayo, Bamidele O, Mosley, Thomas H, Lyon, Helen N, Kang, Sun J, Rotimi, Charles N, Cooper, Richard S, Franceschini, Nora, Curb, J David, Martin, Lisa W, Eaton, Charles B, Kardia, Sharon LR, Taylor, Herman A, Caulfield, Mark J, Ehret, Georg B, Johnson, Toby, Studies, The International Consortium for Blood Pressure Genome-wide Association, Munroe, Patricia B, Rice, Kenneth M, Bochud, Murielle, Johnson, Andrew D, Chasman, Daniel I, Smith, Albert V, Tobin, Martin D, Verwoert, Germaine C, Hwang, Shih-Jen, Pihur, Vasyl, Vollenweider, Peter, O'Reilly, Paul F, Amin, Najaf, Bragg-Gresham, Jennifer L, Teumer, Alexander, Glazer, Nicole L, Launer, Lenore, Zhao, Jing Hua, Aulchenko, Yurii, Heath, Simon, Sõber, Siim, Parsa, Afshin, Luan, Jian'an, Arora, Pankaj, Dehghan, Abbas, Zhang, Feng, Lucas, Gavin, Hicks, Andrew A, Jackson, Anne U, Peden, John F, Tanaka, Toshiko, Wild, Sarah H, Rudan, Igor, Igl, Wilmar, Milaneschi, Yuri, Parker, Alex N, Fava, Cristiano, Chambers, John C, Kumari, Meena, JinGo, Min, van der Harst, Pim, Kao, Wen Hong Linda, Sjögren, Marketa, Vinay, DG, Alexander, Myriam, Tabara, Yasuharu, Shaw-Hawkins, Sue, Whincup, Peter H, Liu, Yongmei, Shi, Gang, Kuusisto, Johanna, Seielstad, Mark, Sim, Xueling, Nguyen, Khanh-Dung Hoang, Lehtimäki, Terho, Matullo, Giuseppe, Wu, Ying, Gaunt, Tom R, and Onland-Moret, N Charlotte

Subjects
Biological Sciences, Genetics, Clinical Research, Hypertension, Human Genome, Cardiovascular, Aetiology, 2.1 Biological and endogenous factors, Adult, Black or African American, Aged, Blood Pressure, Cohort Studies, Diastole, Female, Genetic Loci, Genome-Wide Association Study, Genotype, Humans, Male, Middle Aged, Phenotype, Polymorphism, Single Nucleotide, Systole, White People, International Consortium for Blood Pressure Genome-wide Association Studies, Medical and Health Sciences, Genetics & Heredity
Abstract

The prevalence of hypertension in African Americans (AAs) is higher than in other US groups; yet, few have performed genome-wide association studies (GWASs) in AA. Among people of European descent, GWASs have identified genetic variants at 13 loci that are associated with blood pressure. It is unknown if these variants confer susceptibility in people of African ancestry. Here, we examined genome-wide and candidate gene associations with systolic blood pressure (SBP) and diastolic blood pressure (DBP) using the Candidate Gene Association Resource (CARe) consortium consisting of 8591 AAs. Genotypes included genome-wide single-nucleotide polymorphism (SNP) data utilizing the Affymetrix 6.0 array with imputation to 2.5 million HapMap SNPs and candidate gene SNP data utilizing a 50K cardiovascular gene-centric array (ITMAT-Broad-CARe [IBC] array). For Affymetrix data, the strongest signal for DBP was rs10474346 (P= 3.6 × 10(-8)) located near GPR98 and ARRDC3. For SBP, the strongest signal was rs2258119 in C21orf91 (P= 4.7 × 10(-8)). The top IBC association for SBP was rs2012318 (P= 6.4 × 10(-6)) near SLC25A42 and for DBP was rs2523586 (P= 1.3 × 10(-6)) near HLA-B. None of the top variants replicated in additional AA (n = 11 882) or European-American (n = 69 899) cohorts. We replicated previously reported European-American blood pressure SNPs in our AA samples (SH2B3, P= 0.009; TBX3-TBX5, P= 0.03; and CSK-ULK3, P= 0.0004). These genetic loci represent the best evidence of genetic influences on SBP and DBP in AAs to date. More broadly, this work supports that notion that blood pressure among AAs is a trait with genetic underpinnings but also with significant complexity.

Published
2011

22. Comparison of setup accuracy of optical surface image versus orthogonal x‐ray images for VMAT of the left breast using deep‐inspiration breath‐hold

Author

Lu, Wei, primary, Hong, Linda X., additional, Yamada, Nelson, additional, Berry, Sean L., additional, Song, Yulin, additional, Choi, Wookjin, additional, Cerviño, Laura I., additional, Tang, Xiaoli, additional, Mechalakos, James G., additional, Romesser, Paul B., additional, Powell, Simon, additional, and Li, Guang, additional

Published
2023
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32. Association of Arterial Stiffness and Central Pressure With Cognitive Function in Incident Hemodialysis Patients: The PACE Study

Author

Esther D. Kim, Lucy A. Meoni, Bernard G. Jaar, Tariq Shafi, Wen Hong Linda Kao, Michelle M. Estrella, Rulan Parekh, and Stephen M. Sozio

Subjects
arterial stiffness, central blood pressure, cognitive function, end-stage renal disease, hemodialysis, vascular disease, Diseases of the genitourinary system. Urology, RC870-923
Abstract

Cognitive impairment commonly occurs in hemodialysis patients, with vascular disease potentially implicated in its pathogenesis. However, the relationship of detailed vascular assessment with cognitive function in patients new to hemodialysis has not been demonstrated. Methods: In a prospective study of incident hemodialysis participants enrolled in the Predictors of Arrhythmic and Cardiovascular Risk in ESRD (PACE) study, we determined aortic stiffness by pulse-wave velocity (PWV), systemic arterial stiffness by the augmentation index (AIx) and central pulse pressure (cPP), and examined their associations with cognitive processing speed, executive function, and global cognitive impairment measured by the Trail making test A (TMTA), Trail making test B (TMTB), and the modified Mini-Mental State Exam (3MS). Results: Mean baseline age was 55 ± 13 years, 58% were male, 72% were African American, 35% had coronary artery disease, 55% had diabetes, and 10% had cognitive impairment. At baseline, higher PWV and cPP were associated with a longer TMTA, and a higher PWV was associated with a longer TMTB, but the associations were attenuated after multivariable adjustment. At 1 year, PWV was not independently associated with TMTA, TMTB, or 3MS. However, unadjusted and adjusted analyses revealed every 10% increase in AIx and 10 mm Hg increase in cPP were associated with longer TMTB (time differenceAIx: 0.14; 95% confidence interval [CI]: 0.02−0.25 log-seconds; time differencecPP: 0.11; 95% CI: 0.05−0.17 log-seconds) and global cognitive impairment (odds ratio [OR]AIx: 10.23; 95% CI: 1.77−59.00; ORcPP: 2.88; 95% CI: 1.48−5.59). Discussion: Higher AIx and cPP, which are indicative of abnormal wave reflections in distal vessels, are associated with, and might contribute to, declining cognitive function in patients starting hemodialysis.

Published
2017
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42. Accuracy and efficiency of patient setup using surface imaging versus skin tattoos for accelerated partial breast irradiation (APBI).

Author

Mueller, Boris, primary, Song, Yulin, additional, Chia-Ko, Wang, additional, Hsu, Hao-Yun, additional, Zhai, Xingchen, additional, Tamas, Paul, additional, Powell, Simon, additional, Cahlon, Oren, additional, McCormick, Beryl, additional, Khan, Atif, additional, Gillespie, Erin, additional, Cervino, Laura, additional, Zhao, Bo, additional, Hong, Linda, additional, and Braunstein, Lior Z., additional

Published
2023
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