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4. Case Report of Anti-Thrombogenicity

Author

Boedecker-Lips, Simone C., primary, Batzke, Katharina, additional, Klimpke, Pascal, additional, Holtz, Stefan, additional, Kraus, Daniel, additional, and Weinmann-Menke, Julia, additional

Published
2023
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7. Influence of Advanced Organ Support (ADVOS) on Cytokine Levels in Patients with Acute-on-Chronic Liver Failure (ACLF)

Author

Kaps, Leonard, primary, Schleicher, Eva Maria, additional, Medina Montano, Carolina, additional, Bros, Matthias, additional, Gairing, Simon Johannes, additional, Ahlbrand, Constantin Johannes, additional, Michel, Maurice, additional, Klimpke, Pascal, additional, Kremer, Wolfgang Maximilian, additional, Holtz, Stefan, additional, Boedecker-Lips, Simone Cosima, additional, Galle, Peter Robert, additional, Kraus, Daniel, additional, Schattenberg, Jörn M., additional, Labenz, Christian, additional, and Weinmann-Menke, Julia, additional

Published
2022
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9. Six-Month Follow-Up after Vaccination with BNT162b2: SARS-CoV-2 Antigen-Specific Cellular and Humoral Immune Responses in Hemodialysis Patients and Kidney Transplant Recipients

Author

Boedecker-Lips, Simone Cosima, primary, Lautem, Anja, additional, Runkel, Stefan, additional, Klimpke, Pascal, additional, Kraus, Daniel, additional, Keil, Philipp, additional, Holtz, Stefan, additional, Tomalla, Vanessa, additional, Marczynski, Paul, additional, Boedecker, Christian Benedikt, additional, Galle, Peter Robert, additional, Koch, Martina, additional, and Weinmann-Menke, Julia, additional

Published
2022
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11. [Untitled]

Author

Holtz, Stefan G., Peltzer, Jörg, and Shirota, Maree

Abstract

In the Middle Ages, rolls were ubiquitous as a writing support. While scholars have long examined the texts and images on rolls, they have rarely taken the manuscripts themselves into account. This volume readdresses this imbalance by focusing on the materiality and various usages of rolls in late medieval England and France. Researchers from England, France, Germany and Singapore demonstrate in 11 contributions how this approach can increase our understanding of the rolls and their contents, as well as the contexts in which they were produced and used.

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13. Immunoadsorption and plasma exchange-Efficient treatment options for neurological autoimmune diseases.

Author

Boedecker SC, Luessi F, Engel S, Kraus D, Klimpke P, Holtz S, Meinek M, Marczynski P, Weinmann A, and Weinmann-Menke J

Subjects
Adolescent, Adult, Aged, Humans, Middle Aged, Prospective Studies, Single-Blind Method, Treatment Outcome, Young Adult, Autoimmune Diseases of the Nervous System therapy, Plasma Exchange adverse effects, Plasmapheresis adverse effects
Abstract

Background: Therapeutic plasma exchange (TPE) and immunoadsorption (IA) are first or second line treatment options in patients with neurological autoimmune diseases, including multiple sclerosis, neuromyelitis optica spectrum disorders (NMSOD), chronic inflammatory demyelinating polyneuropathy, acute inflammatory demyelinating polyradiculoneuropathy (Guillain-Barré syndrome), and autoimmune encephalitis., Methods: In this prospective randomized controlled monocentric study, we assessed safety and efficacy of therapy with IA or TPE in patients with neurological autoimmune diseases. Treatment response was assessed using various neurological scores as well by measuring immunoglobulin and cytokine concentrations. Clinical outcome was evaluated by application of specific scores for the underlying diseases., Results: A total of 32 patients were analyzed. Among these, 19 patients were treated with TPE and 13 patients with IA. IA and TPE therapy showed a comparable significant treatment response. In patients with MS and NMOSD, mean EDSS before and after treatment showed a significant reduction after treatment with IA. We observed a significant reduction of the pro-inflammatory cytokines IL-12, lL-17, IL-6, INF-γ, and tumor necrosis factor alpha during IA treatment, whereas this reduction was not seen in patients treated with TPE., Conclusions: In summary, both IA and TPE were effective and safe procedures for treating neurological autoimmune diseases. However, there was a trend towards longer therapy response in patients treated with IA compared to TPE, possibly related to a reduction in plasma levels of pro-inflammatory cytokines seen only in the IA-treated group., (© 2021 The Authors. Journal of Clinical Apheresis published by Wiley Periodicals LLC.)

Published
2022
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