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Your search keyword '"Holmberg, Staffan"' showing total 12 results
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12 results on '"Holmberg, Staffan"'

1. Treatment strategies, outcomes and prognostic factors in 291 patients with secondary CNS involvement by diffuse large B-cell lymphoma

Author

El-Galaly, Tarec Christoffer, Cheah, Chan Yoon, Bendtsen, Mette Dahl, Nowakowski, Grzegorz S., Kansara, Roopesh, Savage, Kerry J., Connors, Joseph M., Sehn, Laurie H., Goldschmidt, Neta, Shaulov, Adir, Farooq, Umar, Link, Brian K., Ferreri, Andrés J.M., Calimeri, Teresa, Cecchetti, Caterina, Dann, Eldad J., Thompson, Carrie A., Inbar, Tsofia, Maurer, Matthew J., Gade, Inger Lise, Juul, Maja Bech, Hansen, Jakob W., Holmberg, Staffan, Larsen, Thomas S., Cordua, Sabrina, Mikhaeel, N. George, Hutchings, Martin, Seymour, John F., Clausen, Michael Roost, Smith, Daniel, Opat, Stephen, Gilbertson, Michael, Thanarajasingam, Gita, and Villa, Diego

Published
2018
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2. The number of extranodal sites assessed by PET/CT scan is a powerful predictor of CNS relapse for patients with diffuse large B-cell lymphoma: An international multicenter study of 1532 patients treated with chemoimmunotherapy

Author

El-Galaly, Tarec Christoffer, Villa, Diego, Michaelsen, Thomas Yssing, Hutchings, Martin, Mikhaeel, Nabegh George, Savage, Kerry J., Sehn, Laurie H., Barrington, Sally, Hansen, Jakob W., Smith, Daniel, Rady, Kirsty, Mylam, Karen J., Larsen, Thomas S., Holmberg, Staffan, Juul, Maja B., Cordua, Sabrina, Clausen, Michael R., Jensen, Kristina B., Johnsen, Hans E., Seymour, John F., Connors, Joseph M., de Nully Brown, Peter, Bøgsted, Martin, and Cheah, Chan Y.

Published
2017
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3. Abstract B129: Human endogenous retroviruses as a potential reservoir for T-cell mediated cancer immunotherapy

Author

Saini, Sunil Kumar, primary, Bjerregaard, Anne-Mette, additional, Ørskov, Andreas D., additional, Unnikrishnan, Ashwin, additional, Holmberg, Staffan, additional, Anande, Govardhan, additional, Bentzen, Amalie Kai, additional, Szallasi, Zoltan, additional, Eklund, Aron C., additional, Grønbæk, Kirsten, additional, and Hadrup, Sine Reker, additional

Published
2019
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6. An International Collaborative Study of Outcome and Prognostic Factors in Patients with Secondary CNS Involvement By Diffuse Large B-Cell Lymphoma

Author

El-Galaly, Tarec Christoffer, primary, Cheah, Chan Yoon, additional, Bendtsen, Mette Dahl, additional, Thanarasjasingam, Gita, additional, Kansara, Roopesh, additional, Savage, Kerry J, additional, Connors, Joseph M., additional, Goldschmidt, Neta, additional, Shaulov, Adir, additional, Farooq, Umar, additional, Sehn, Laurie H, additional, Dann, Eldad J, additional, Thompson, Carrie A, additional, Inbar, Tsofia, additional, Link, Brian K, additional, Maurer, Matthew J, additional, Gade, Inger Lise, additional, Juul, Maja Bech, additional, Hansen, Jakob W, additional, Holmberg, Staffan, additional, Larsen, Thomas S, additional, Opat, Stephen, additional, Mikhaeel, N George, additional, Seymour, John F, additional, Clausen, Michael Roost, additional, Smith, Daniel, additional, Gilbertson, Michael, additional, Nowakowski, Grzegorz S, additional, Cordua, Sabrina, additional, Hutchings, Martin, additional, and Villa, Diego, additional

Published
2016
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7. Principals' goal-setting and actions while managing : An explorative study of locally-created goals and principals’ actions while managing their schools

Author

Holmberg, Staffan

Subjects
Skolledarskap, Leadership behavior, School leadership, Principal actions, Ledarskapsbeteende, Rektorers ageranden, Målsättning, Goal-Setting
Abstract

Large amounts of research have been performed regarding goal-setting and leadership and its effect on organizational performance. However, in school settings, the amount of performed research about leadership performance in relation to goal-setting is limited. The aim of the study was, therefore, to analyze specificity of locally-created goals and the principal’s performance-affecting behaviors during meetings, especially in relation to set goals. Based on Komaki’s research on managerial behavior structured observation was used to analyze the principal’s actions while leading meetings. Adding to the observations Locke & Latham’s Goal-Setting Theory was used to perform a content analysis investigating the specificity of written goals. In total, 56 goals from seven schools in a large county/municipality in Sweden were analyzed. In total, 1,235 minutes of a principal leading their staff during meetings were recorded and analyzed. A majority of the goals written in the schools’ work-plans lacked specificity. This study found that principals talked about their goals while leading their staff at meetings, and they changed their behavior towards a more performance-affecting management style while doing so.

Published
2014

8. Uterine, but not ovarian, female reproductive organ involvement at presentation by diffuse large B‐cell lymphoma is associated with poor outcomes and a high frequency of secondary CNS involvement

Author

El‐Galaly, Tarec Christoffer, primary, Cheah, Chan Y., additional, Hutchings, Martin, additional, Mikhaeel, Nabegh George, additional, Savage, Kerry J., additional, Sehn, Laurie H., additional, Barrington, Sally, additional, Hansen, Jakob W., additional, Poulsen, Mette Ø., additional, Smith, Daniel, additional, Rady, Kirsty, additional, Mylam, Karen J., additional, Larsen, Thomas S., additional, Holmberg, Staffan, additional, Juul, Maja B., additional, Cordua, Sabrina, additional, Clausen, Michael R., additional, Jensen, Kristina B., additional, Bøgsted, Martin, additional, Johnsen, Hans E., additional, Seymour, John F., additional, Connors, Joseph M., additional, Brown, Peter d. N., additional, and Villa, Diego, additional

Published
2016
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9. The Absolute Number of Extranodal Sites Detected By PET-CT Is a Powerful Predictor of Secondary Central Nervous System Involvement in Patients with Diffuse Large B-Cell Lymphoma Treated with R-CHOP

Author

Cheah, Chan Yoon, primary, Hutchings, Martin, additional, Rady, Kirsty, additional, Savage, Kerry J., additional, Alzahrani, Musa F., additional, Sehn, Laurie H., additional, Barrington, Sally, additional, Mikhaeel, George, additional, Kansara, Roopesh R., additional, Hansen, Jakob Werner, additional, Smith, Daniel, additional, Mylam, Karen Juul, additional, Larsen, Thomas Stauffer, additional, Holmberg, Staffan, additional, Juul, Maja, additional, Cordua, Sabrina, additional, Clausen, Michael Roost, additional, Jensen, Kkristina Buchardi, additional, Bogsted, Martin, additional, Johnsen, Hans Erik, additional, Connors, Joseph M., additional, Brown, Peter de Nully, additional, Seymour, John F., additional, Villa, Diego, additional, and El-Galaly, Tarec Christoffer, additional

Published
2015
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10. The International Pictogram Symbol System.

Author

Holmberg, Staffan and Rudin, Kerstin

Subjects
MEANS of communication for people with disabilities, SIGNS & symbols, VISUAL communication, COMMUNICATIVE disorders, SPEECH disorders, INTELLECTUAL disabilities
Abstract

The article provides information about the pictogram, a system of graphical symbols in white against a black background. The pictogram system gives individuals who are mentally retarded and those who are limited in their ability to speak, read, and write a language of pictures that support their thoughts and memory and helps them to communicate.

Published
2002

11. Activation of T Cells Specific to Endogenous Retroviral Peptides: Possible Association with Clinical Response to Azacitidine in Myeloid Malignancies

Author

Ørskov, Andreas Due, Saini, Sunil Kumar, Bjerregaard, Anne-Mette, Otani, Hitoshi, Holmberg, Staffan, Hansen, Jakob Werner, Treppendahl, Marianne Bach, Gang, Anne Ortved, Dufva, Inge Høgh, Liang, Gangning, Eklund, Aron Charles, Jones, Peter A., Grønbæk, Kirsten, and Hadrup, Sine Reker

Abstract

DNA methyltransferase inhibitors (DNMTi's), 5-azacytidine (5-aza-CR, azacitidine) and 5-aza-2′-deoxycytidine (5-aza-CdR, decitabine), are drugs of choice for patients with higher-risk myelodysplastic syndromes (MDS). Although DNMTi's have shown clinical benefits, their mode of action is not completely understood. In vitrostudies have shown that low-dose DNMTi causes up-regulation of transcripts derived from human endogenous retroviruses (HERVs) in target cells that may give rise to double and single stranded RNA formation that are sensed by the cells as foreign. This in turn induces the viral defense pathway that elicits an interferon response, which may play an important role in the efficacies of DNMTi's. In this study we wanted to explore whether DNMTi-treatment in patients causes up-regulation of HERVs and formation of HERV-derived peptides in vivothat can stimulate an adaptive immune response against the malignant cells.

Published
2017
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12. [Cancer immune therapy for the treatment of haematological malignancies].

Author

Holmström MO, Klausen U, Jørgensen NG, Holmberg S, Grauslund J, Met Ö, Svane IM, Pedersen LM, Knudsen LM, Hasselbalch HC, and Andersen MH

Subjects
Antigens, Neoplasm, Humans, Hematologic Neoplasms therapy, Immunotherapy, Myeloproliferative Disorders
Abstract

Cancer immune therapy is now used routinely for the treatment of several solid malignancies, albeit just recently having entered the clinic for treatment of haematological malignancies. Several studies demonstrate that cancer immune therapy is a promising treatment modality for the latter. Especially treatment with chimeric antigen receptor T cells for acute lymphoblastic leukaemia and lymphoma is promising. Other promising treatment modalities are immune check point inhibitors for both lymphoid and myeloid malignancies, as well as therapeutic cancer vaccination targeting tumour antigens.

Published
2019

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