2,799 results on '"Hollnagel, A"'
Search Results
2. Performance of a First Full-Size WOM-Based Liquid Scintillator Detector Cell as Prototype for the SHiP Surrounding Background Tagger
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Alt, J., Bezshyyko, O., Böhles, M., Brignoli, A., Conaboy, A., Deucher, P., Eckardt, C., Ernst, A., Fischer, H., Hollnagel, A., Jadidi, M., Lacker, H., Lyons, F., Molzberger, T., Ochoa, S., Orlov, V., Reghunath, A., Rehbein, F., Schaaf, M., Scharf, C., Schmidt, J., Schumann, M., Vagts, A., and Wurm, M.
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Physics - Instrumentation and Detectors ,High Energy Physics - Experiment - Abstract
As a prototype detector for the SHiP Surrounding Background Tagger (SBT), we constructed a cell (120 cm x 80 cm x 25 cm) made from corten steel that is filled with liquid scintillator (LS) composed of linear alkylbenzene (LAB) and 2,5-diphenyloxazole (PPO). The detector is equipped with two Wavelength-shifting Optical Modules (WOMs) for light collection of the primary scintillation photons. Each WOM consists of an acrylic tube that is dip-coated with a wavelength-shifting layer on its surface. Via internal total reflection, the secondary photons emitted by the molecules of the wavelength shifter are guided to a ring-shaped array of 40 silicon photomultipliers (SiPMs) coupled to the WOM for light detection. The granularity of these SiPM arrays provides an innovative method to gain spatial information on the particle crossing point. Several improvements in the detector design significantly increased the light yield with respect to earlier proof-of-principle detectors. We report on the performance of this prototype detector during an exposure to high-energy positrons at the DESY II test beam facility by measuring the collected integrated yield and the signal time-of-arrival in each of the SiPM arrays. The resulting detection efficiency and reconstructed energy deposition of the incident positrons are presented, as well as the spatial and time resolution of the detector. These results are then compared to Monte Carlo simulations., Comment: Corresponding authors: A. Brignoli, A. Hollnagel, H. Lacker, F. Lyons. Prepared for submission to JINST. Updated version v3: Minor revision of the manuscript with touch-up of figures and (sub)section titles
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- 2023
3. Zoom Improv is accessible and enhances medical student empathy
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Maya F. Amjadi, Jacqueline Kociubuk, Fauzia Hollnagel, Vera K. Tsenkova, and Amy B. Zelenski
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Medical improv ,Zoom improv ,Virtual learning ,Empathy ,Medical education ,Special aspects of education ,LC8-6691 ,Medicine - Abstract
Abstract Background Empathy declines during medical training, despite its importance. Methodology In this randomized controlled trial, we assessed the impact of Zoom improv on medical student empathy using a concurrent mixed-methods approach. Quantitative assessment with three survey tools and qualitative assessment by content analysis of Zoom session field notes were conducted. Results Zoom improv participants had higher empathy scores in perspective-taking and fantasy and lower scores in personal distress compared with the control group. Medical students who participated in Zoom improv exercised emotional expression, active listening, and giving “gifts,” which apply to healthcare settings in which affirming team members with empathic concern can advance communication, patient rapport, and teamwork. Discussion This pilot study highlights promising findings for the incorporation of Zoom improv in medical education, including enhanced empathy, self-reflection, and understanding how these skills impact work in healthcare. Future studies may expand on the optimal timing to teach improv. Future studies conducted on virtual platforms may also further investigate our finding that the fantasy domain of empathy increases after Zoom improv sessions, whereas this increase in fantasy was absent from previous in-person studies. Given the increase in telehealth and virtual medical visits, exercising empathy skills through a screen during training may be an important addition to medical curricula.
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- 2024
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4. Zoom Improv is accessible and enhances medical student empathy
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Amjadi, Maya F., Kociubuk, Jacqueline, Hollnagel, Fauzia, Tsenkova, Vera K., and Zelenski, Amy B.
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- 2024
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5. Reconstruction of 400 GeV/c proton interactions with the SHiP-charm project
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SHiP Collaboration, C. Ahdida, A. Akmete, R. Albanese, A. Alexandrov, F. Alicante, J. Alt, S. Aoki, G. Arduini, J. J. Back, F. Baaltasar Dos Santos, F. Bardou, G. J. Barker, M. Battistin, J. Bauche, A. Bay, V. Bayliss, C. Betancourt, I. Bezshyiko, O. Bezshyyko, D. Bick, S. Bieschke, A. Blanco, J. Boehm, M. Bogomilov, I. Boiarska, K. Bondarenko, W. M. Bonivento, J. Borburgh, A. Boyarsky, R. Brenner, D. Breton, A. Brignoli, V. Büscher, A. Buonaura, S. Buontempo, S. Cadeddu, M. Calviani, M. Campanelli, M. Casolino, D. Centanni, N. Charitonidis, P. Chau, J. Chauveau, K.-Y. Choi, A. Chumakov, V. Cicero, M. Climescu, A. Conaboy, L. Congedo, K. Cornelis, M. Cristinziani, A. Crupano, G. M. Dallavalle, A. Datwyler, N. D’Ambrosio, G. D’Appollonio, R. de Asmundis, J. De Carvalho Saraiva, G. De Lellis, M. de Magistris, A. De Roeck, M. De Serio, D. De Simone, A. Di Crescenzo, L. Di Giulio, C. Dib, H. Dijkstra, L. A. Dougherty, V. Drohan, A. Dubreuil, O. Durhan, M. Ehlert, E. Elikkaya, F. Fabbri, F. Fedotovs, M. Ferrillo, M. Ferro-Luzzi, R. A. Fini, H. Fischer, P. Fonte, C. Franco, M. Fraser, R. Fresa, R. Froeschl, T. Fukuda, G. Galati, J. Gall, L. Gatignon, V. Gentile, B. Goddard, L. Golinka-Bezshyyko, A. Golutvin, P. Gorbounov, V. Gorkavenko, A. L. Grandchamp, E. Graverini, J.-L. Grenard, D. Grenier, A. M. Guler, G. J. Haefeli, C. Hagner, H. Hakobyan, I. W. Harris, E. van Herwijnen, C. Hessler, A. Hollnagel, B. Hosseini, G. Iaselli, A. Iuliano, R. Jacobsson, D. Joković, M. Jonker, I. Kadenko, V. Kain, B. Kaiser, C. Kamiscioglu, K. Kershaw, G. Khoriauli, Y. G. Kim, N. Kitagawa, J.-W. Ko, K. Kodama, D. I. Kolev, M. Komatsu, A. Kono, S. Kormannshaus, I. Korol, A. Korzenev, V. Kostyukhin, E. Koukovini Platia, S. Kovalenko, H. M. Lacker, M. Lamont, O. Lantwin, A. Lauria, K. S. Lee, K. Y. Lee, N. Leonardo, J.-M. Lévy, V. P. Loschiavo, L. Lopes, E. Lopez Sola, F. Lyons, V. Lyubovitskij, J. Maalmi, A.-M. Magnan, Y. Manabe, M. Manfredi, S. Marsh, A. M. Marshall, P. Mermod, A. Miano, S. Mikado, A. Mikulenko, D. A. Milstead, A. Montanari, M. C. Montesi, K. Morishima, Y. Muttoni, N. Naganawa, M. Nakamura, T. Nakano, P. Ninin, A. Nishio, S. Ogawa, J. Osborne, M. Ovchynnikov, N. Owtscharenko, P. H. Owen, P. Pacholek, B. D. Park, A. Pastore, M. Patel, A. Perillo-Marcone, G. L. Petkov, K. Petridis, J. Prieto Prieto, A. Prota, A. Quercia, A. Rademakers, A. Rakai, T. Rawlings, F. Redi, A. Reghunath, S. Ricciardi, M. Rinaldesi, Volodymyr Rodin, Viktor Rodin, P. Robbe, A. B. Rodrigues Cavalcante, H. Rokujo, T. Rovelli, O. Ruchayskiy, T. Ruf, F. Sanchez Galan, P. Santos Diaz, A. Sanz Ull, O. Sato, J. S. Schliwinski, W. Schmidt-Parzefall, M. Schumann, N. Serra, S. Sgobba, O. Shadura, M. Shaposhnikov, L. Shchutska, H. Shibuya, L. Shihora, S. Shirobokov, S. B. Silverstein, S. Simone, R. Simoniello, G. Soares, J. Y. Sohn, A. Sokolenko, E. Solodko, L. Stoel, M. E. Stramaglia, D. Sukhonos, Y. Suzuki, S. Takahashi, J. L. Tastet, I. Timiryasov, V. Tioukov, D. Tommasini, M. Torii, N. Tosi, D. Treille, R. Tsenov, G. Vankova-Kirilova, F. Vannucci, P. Venkova, V. Venturi, S. Vilchinski, Heinz Vincke, Helmut Vincke, C. Visone, S. van Waasen, R. Wanke, P. Wertelaers, O. Williams, J.-K. Woo, M. Wurm, S. Xella, D. Yilmaz, A. U. Yilmazer, C. S. Yoon, and J. Zimmerman
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Astrophysics ,QB460-466 ,Nuclear and particle physics. Atomic energy. Radioactivity ,QC770-798 - Abstract
Abstract The SHiP-charm project was proposed to measure the associated charm production induced by 400 GeV/c protons in a thick target, including the contribution from cascade production. An optimisation run was performed in July 2018 at CERN SPS using a hybrid setup. The high resolution of nuclear emulsions acting as vertex detector was complemented by electronic detectors for kinematic measurements and muon identification. Here we present first results on the analysis of nuclear emulsions exposed in the 2018 run, which prove the capability of reconstructing proton interaction vertices in a harsh environment, where the signal is largely dominated by secondary particles produced in hadronic and electromagnetic showers within the lead target.
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- 2024
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6. Reconstruction of 400 GeV/c proton interactions with the SHiP-charm project
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Ahdida, C., Akmete, A., Albanese, R., Alexandrov, A., Alicante, F., Alt, J., Aoki, S., Arduini, G., Back, J. J., Dos Santos, F. Baaltasar, Bardou, F., Barker, G. J., Battistin, M., Bauche, J., Bay, A., Bayliss, V., Betancourt, C., Bezshyiko, I., Bezshyyko, O., Bick, D., Bieschke, S., Blanco, A., Boehm, J., Bogomilov, M., Boiarska, I., Bondarenko, K., Bonivento, W. M., Borburgh, J., Boyarsky, A., Brenner, R., Breton, D., Brignoli, A., Büscher, V., Buonaura, A., Buontempo, S., Cadeddu, S., Calviani, M., Campanelli, M., Casolino, M., Centanni, D., Charitonidis, N., Chau, P., Chauveau, J., Choi, K.-Y., Chumakov, A., Cicero, V., Climescu, M., Conaboy, A., Congedo, L., Cornelis, K., Cristinziani, M., Crupano, A., Dallavalle, G. M., Datwyler, A., D’Ambrosio, N., D’Appollonio, G., de Asmundis, R., De Carvalho Saraiva, J., De Lellis, G., de Magistris, M., De Roeck, A., De Serio, M., De Simone, D., Di Crescenzo, A., Di Giulio, L., Dib, C., Dijkstra, H., Dougherty, L. A., Drohan, V., Dubreuil, A., Durhan, O., Ehlert, M., Elikkaya, E., Fabbri, F., Fedotovs, F., Ferrillo, M., Ferro-Luzzi, M., Fini, R. A., Fischer, H., Fonte, P., Franco, C., Fraser, M., Fresa, R., Froeschl, R., Fukuda, T., Galati, G., Gall, J., Gatignon, L., Gentile, V., Goddard, B., Golinka-Bezshyyko, L., Golutvin, A., Gorbounov, P., Gorkavenko, V., Grandchamp, A. L., Graverini, E., Grenard, J.-L., Grenier, D., Guler, A. M., Haefeli, G. J., Hagner, C., Hakobyan, H., Harris, I. W., van Herwijnen, E., Hessler, C., Hollnagel, A., Hosseini, B., Iaselli, G., Iuliano, A., Jacobsson, R., Joković, D., Jonker, M., Kadenko, I., Kain, V., Kaiser, B., Kamiscioglu, C., Kershaw, K., Khoriauli, G., Kim, Y. G., Kitagawa, N., Ko, J.-W., Kodama, K., Kolev, D. I., Komatsu, M., Kono, A., Kormannshaus, S., Korol, I., Korzenev, A., Kostyukhin, V., Platia, E. Koukovini, Kovalenko, S., Lacker, H. M., Lamont, M., Lantwin, O., Lauria, A., Lee, K. S., Lee, K. Y., Leonardo, N., Lévy, J.-M., Loschiavo, V. P., Lopes, L., Sola, E. Lopez, Lyons, F., Lyubovitskij, V., Maalmi, J., Magnan, A.-M., Manabe, Y., Manfredi, M., Marsh, S., Marshall, A. M., Mermod, P., Miano, A., Mikado, S., Mikulenko, A., Milstead, D. A., Montanari, A., Montesi, M. C., Morishima, K., Muttoni, Y., Naganawa, N., Nakamura, M., Nakano, T., Ninin, P., Nishio, A., Ogawa, S., Osborne, J., Ovchynnikov, M., Owtscharenko, N., Owen, P. H., Pacholek, P., Park, B. D., Pastore, A., Patel, M., Perillo-Marcone, A., Petkov, G. L., Petridis, K., Prieto, J. Prieto, Prota, A., Quercia, A., Rademakers, A., Rakai, A., Rawlings, T., Redi, F., Reghunath, A., Ricciardi, S., Rinaldesi, M., Rodin, Volodymyr, Rodin, Viktor, Robbe, P., Cavalcante, A. B. Rodrigues, Rokujo, H., Rovelli, T., Ruchayskiy, O., Ruf, T., Galan, F. Sanchez, Diaz, P. Santos, Ull, A. Sanz, Sato, O., Schliwinski, J. S., Schmidt-Parzefall, W., Schumann, M., Serra, N., Sgobba, S., Shadura, O., Shaposhnikov, M., Shchutska, L., Shibuya, H., Shihora, L., Shirobokov, S., Silverstein, S. B., Simone, S., Simoniello, R., Soares, G., Sohn, J. Y., Sokolenko, A., Solodko, E., Stoel, L., Stramaglia, M. E., Sukhonos, D., Suzuki, Y., Takahashi, S., Tastet, J. L., Timiryasov, I., Tioukov, V., Tommasini, D., Torii, M., Tosi, N., Treille, D., Tsenov, R., Vankova-Kirilova, G., Vannucci, F., Venkova, P., Venturi, V., Vilchinski, S., Vincke, Heinz, Vincke, Helmut, Visone, C., van Waasen, S., Wanke, R., Wertelaers, P., Williams, O., Woo, J.-K., Wurm, M., Xella, S., Yilmaz, D., Yilmazer, A. U., Yoon, C. S., and Zimmerman, J.
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- 2024
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7. Updated constraints on sterile neutrino mixing in the OPERA experiment using a new $\nu_e$ identification method
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Agafonova, N., Alexandrov, A., Anokhina, A., Aoki, S., Ariga, A., Ariga, T., Bertolin, A., Bozza, C., Brugnera, R., Buontempo, S., Chernyavskiy, M., Chukanov, A., Consiglio, L., D'Ambrosio, N., De Lellis, G., De Serio, M., Sanchez, P. del Amo, Di Crescenzo, A., Di Ferdinando, D., Di Marco, N., Dmitrievsky, S., Dracos, M., Duchesneau, D., Dusini, S., Dzhatdoev, T., Ebert, J., Ereditato, A., Fini, R. A., Fukuda, T., Galati, G., Garfagnini, A., Gentile, V., Goldberg, J., Gorbunov, S., Gornushkin, Y., Grella, G., Guler, A. M., Gustavino, C., Hagner, C., Hara, T., Hayakawa, T., Hollnagel, A., Ishiguro, K., Iuliano, A., Jakovcic, K., Jollet, C., Kamiscioglu, C., Kamiscioglu, M., Kim, S. H., Kitagawa, N., Klicek, B., Kodama, K., Komatsu, M., Kose, U., Kreslo, I., Laudisio, F., Lauria, A., Longhin, A., Loverre, P., Malgin, A., Mandrioli, G., Matsuo, T., Matveev, V., Mauri, N., Medinaceli, E., Meregaglia, A., Mikado, S., Miyanishi, M., Mizutani, F., Monacelli, P., Montesi, M. C., Morishima, K., Muciaccia, M. T., Naganawa, N., Naka, T., Nakamura, M., Nakano, T., Niwa, K., Ogawa, S., Okateva, N., Ozaki, K., Paoloni, A., Paparella, L., Park, B. D., Pasqualini, L., Pastore, A., Patrizii, L., Pessard, H., Podgrudkov, D., Polukhina, N., Pozzato, M., Pupilli, F., Roda, M., Roganova, T., Rokujo, H., Rosa, G., Ryazhskaya, O., Sato, O., Schembri, A., Shakiryanova, I., Shchedrina, T., Shibayama, E., Shibuya, H., Shiraishi, T., Simone, S., Sirignano, C., Sirri, G., Sotnikov, A., Spinetti, M., Stanco, L., Starkov, N., Stellacci, S. M., Stipcevic, M., Strolin, P., Takahashi, S., Tenti, M., Terranova, F., Tioukov, V., Tufanli, S., Vasina, S., Vilain, P., Voevodina, E., Votano, L., Vuilleumier, J. L., Wilquet, G., and Yoon, C. S.
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High Energy Physics - Experiment - Abstract
This paper describes a new $\nu_e$ identification method specifically designed to improve the low-energy ($< 30\,\mathrm{GeV}$) $\nu_e$ identification efficiency attained by enlarging the emulsion film scanning volume with the next generation emulsion readout system. A relative increase of 25-70% in the $\nu_e$ low-energy region is expected, leading to improvements in the OPERA sensitivity to neutrino oscillations in the framework of the 3 + 1 model. The method is applied to a subset of data where the detection efficiency increase is expected to be more relevant, and one additional $\nu_e$ candidate is found. The analysis combined with the $\nu_\tau$ appearance results improves the upper limit on $\sin^2 2\theta_{\mu e}$ to 0.016 at 90% C.L. in the MiniBooNE allowed region $\Delta m^2_{41} \sim 0.3\,\mathrm{eV}^2$., Comment: 13 pages, 6 figures
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- 2022
8. Introduction
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Asgary, Nader H., primary, Maccari, Emerson A., additional, Hollnagel, Heloisa C., additional, and Bueno, Ricardo L.P., additional
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- 2024
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9. Cases
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Asgary, Nader H., primary, Maccari, Emerson A., additional, Hollnagel, Heloisa C., additional, and Bueno, Ricardo L.P., additional
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- 2024
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10. Culture, entrepreneurship, and development
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Asgary, Nader H., primary, Maccari, Emerson A., additional, Hollnagel, Heloisa C., additional, and Bueno, Ricardo L.P., additional
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- 2024
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11. Ethics and corporate social responsibility
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Asgary, Nader H., primary, Maccari, Emerson A., additional, Hollnagel, Heloisa C., additional, and Bueno, Ricardo L.P., additional
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- 2024
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12. Sustainability as a strategy for business operation
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Asgary, Nader H., primary, Maccari, Emerson A., additional, Hollnagel, Heloisa C., additional, and Bueno, Ricardo L.P., additional
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- 2024
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13. Marketing, technology, and entrepreneurship
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Asgary, Nader H., primary, Maccari, Emerson A., additional, Hollnagel, Heloisa C., additional, and Bueno, Ricardo L.P., additional
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- 2024
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14. Entrepreneurship and development in the era of globalization
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Asgary, Nader H., primary, Maccari, Emerson A., additional, Hollnagel, Heloisa C., additional, and Bueno, Ricardo L.P., additional
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- 2024
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15. Personality, experience, and training
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Asgary, Nader H., primary, Maccari, Emerson A., additional, Hollnagel, Heloisa C., additional, and Bueno, Ricardo L.P., additional
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- 2024
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16. Institutions, governance, and strategy
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Asgary, Nader H., primary, Maccari, Emerson A., additional, Hollnagel, Heloisa C., additional, and Bueno, Ricardo L.P., additional
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- 2024
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17. Creativity, innovation, and development
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Asgary, Nader H., primary, Maccari, Emerson A., additional, Hollnagel, Heloisa C., additional, and Bueno, Ricardo L.P., additional
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- 2024
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18. Essentials of bookkeeping
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Asgary, Nader H., primary, Maccari, Emerson A., additional, Hollnagel, Heloisa C., additional, and Bueno, Ricardo L.P., additional
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- 2024
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19. Financing opportunities and challenges
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Asgary, Nader H., primary, Maccari, Emerson A., additional, Hollnagel, Heloisa C., additional, and Bueno, Ricardo L.P., additional
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- 2024
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20. Technology, communications, and entrepreneurship
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Asgary, Nader H., primary, Maccari, Emerson A., additional, Hollnagel, Heloisa C., additional, and Bueno, Ricardo L.P., additional
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- 2024
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21. Antiviral potential of spirulina in individuals with human immunodeficiency virus or Hepatis C virus infections: A systematic review and meta-analysis
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McKinley, Linda, Acen, Innocent Kelly, Alshannaq, Ahmad, Christensen, Leslie, Dolan, Katherine, Kates, Ashley, Keating, Julie, Musuuza, Jackson, Hollnagel, Fauzia, and Safdar, Nasia
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- 2024
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22. First measurement of the surface tension of a liquid scintillator based on Linear Alkylbenzene (HYBLENE 113)
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SHiP SBT collaboration, Alt, J., Arutinov, J., Bezshyyko, O., Bretz, T., Brignoli, A., Conaboy, A., Deucher, P., De Paola, F., del Giudice, G., di Cristo, C., Fecarotta, O., Fiorillo, A., Fischer, H., Glückler, H., Grewing, C., Hollnagel, A., Lacker, H., Miano, A., Natour, G., Orlov, V., Prota, A., Rehbein, F., Reghunath, A., Salzano, A., Schaaf, M., Scharf, C., Schmidt, J., Schumann, M., Vagts, A., van Waasen, S., and Wurm, M.
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Physics - Instrumentation and Detectors - Abstract
We measured the surface tension of linear alkylbenzene (LAB) HYBLENE 113 mixed with Diphenyloxazole (PPO) as well as of pure LAB HYBLENE 113 as part of material studies for the liquid-scintillator based surround background tagger (SBT) in the proposed SHiP experiment. The measurement was performed using the iron wire method and the surface tension for linear alkyl benzene HYBLENE 113 plus PPO was found to be $(30.0\pm0.6)$ mN/m $22.0\pm 0.5$ {\deg}C and for pure HYBLENE 113, $(29.2\pm 0.6)$ mN/m at $21.0\pm 0.5$ {\deg}C., Comment: 4 pages, 1 figure
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- 2022
23. Evaluating the consistency of judgments derived through both in silico and expert application of the Cramer classification scheme
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Firman, James W., Boobis, Alan, Hollnagel, Heli M., Kaiser, Stefan, Lovell, David P., Moretto, Angelo, Mueller, Severin, Rider, Cynthia V., Schmidt, Florian, Stice, Szabina, Wijeyesakere, Sanjeeva J., Borja, Geraldine, and Patlewicz, Grace
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- 2024
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24. Shifting from the treat-to-target to the early highly effective treatment approach in patients with multiple sclerosis – real-world evidence from Germany
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Steffeni Papukchieva, Ann-Sophie Stratil, Maria Kahn, Nils-Henning Neß, Maike Hollnagel-Schmitz, Vivien Gerencser, Julia Rustemeier, Markus Eberl, Benjamin Friedrich, and Tjalf Ziemssen
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Neurology. Diseases of the nervous system ,RC346-429 - Abstract
Background: While evidence highlights the effectiveness of initiating disease-modifying therapy with a high-efficacy medication for multiple sclerosis (MS) patients with poor prognostic factors, it remains unclear whether this approach has been adopted by a broad range of MS providers in Germany yet. Objective: To assess the adoption of the early highly effective treatment (EHT) compared to the treat-to-target treatment approach with the option of escalating treatment efficacy over time in Germany based on real-world evidence data. Design: Patient-level pharmacy dispensing data from the Permea platform were analysed from 2020 to 2022. Methods: In total, 29,529 therapy beginners (>18 years) were included to analyse shifts in treatment approaches over time and switching behaviour. Medication classification adhered to the German Society of Neurology guidelines and designated fumarates, glatiramer acetate, teriflunomide and interferons as low-efficacy category 1 medications; cladribine and S1P-modulators as medium-efficacy category 2 medications; and alemtuzumab, natalizumab, ocrelizumab, ofatumumab and rituximab (off-label) as high-efficacy category 3 medications. Results: Our results show that 70.0% of patients redeemed their first prescription for category 1 medication, 16.3% for category 2 and 13.7% for category 3 medications. The proportion of prescriptions filled shifted from 2020 to 2022 with a decrease of 14.7% for category 1 drugs and an increase of 12.5% for category 3 drugs. 93.2% of patients stayed on their initially prescribed medication category. 3.2% of category 1 and 3.7% of category 2 therapy beginners escalated to category 3 medication. 3.4% of category 3 medication users de-escalated their treatment to category 1 or category 2. Conclusion: While most individuals started their treatment according to the treat-to-target approach and remained on their initially prescribed medication category, there has been a steadily increasing shift towards the EHT approach since 2020. These insights demonstrate that, while not officially recommended by German guidelines, MS providers increasingly adopt the EHT approach.
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- 2024
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25. Visualising for Safety or Visualisation of Safety?
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Hollnagel, Erik, Le Coze, Jean-Christophe, editor, and Reiman, Teemu, editor
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- 2023
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26. Sensitivity of the SHiP experiment to dark photons decaying to a pair of charged particles
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SHiP Collaboration, Ahdida, C., Akmete, A., Albanese, R., Alexandrov, A., Anokhina, A., Aoki, S., Arduini, G., Atkin, E., Azorskiy, N., Back, J. J., Bagulya, A., Santos, F. Baaltasar Dos, Baranov, A., Bardou, F., Barker, G. J., Battistin, M., Bauche, J., Bay, A., Bayliss, V., Bencivenni, G., Berdnikov, A. Y., Berdnikov, Y. A., Bertani, M., Betancourt, C., Bezshyiko, I., Bezshyyko, O., Bick, D., Bieschke, S., Blanco, A., Boehm, J., Bogomilov, M., Boiarska, I., Bondarenko, K., Bonivento, W. M., Borburgh, J., Boyarsky, A., Brenner, R., Breton, D., Büscher, V., Buonaura, A., Buontempo, S., Cadeddu, S., Calcaterra, A., Calviani, M., Campanelli, M., Casolino, M., Charitonidis, N., Chau, P., Chauveau, J., Chepurnov, A., Chernyavskiy, M., Choi, K. -Y., Chumakov, A., Ciambrone, P., Cicero, V., Congedo, L., Cornelis, K., Cristinziani, M., Crupano, A., Dallavalle, G. M., Datwyler, A., D'Ambrosio, N., D'Appollonio, G., de Asmundis, R., Saraiva, J. De Carvalho, De Lellis, G., de Magistris, M., De Roeck, A., De Serio, M., De Simone, D., Dedenko, L., Dergachev, P., Di Crescenzo, A., Di Giulio, L., Di Marco, N., Dib, C., Dijkstra, H., Dmitrenko, V., Dougherty, L. A., Dolmatov, A., Domenici, D., Donskov, S., Drohan, V., Dubreuil, A., Durhan, O., Ehlert, M., Elikkaya, E., Enik, T., Etenko, A., Fabbri, F., Fedin, O., Fedotovs, F., Felici, G., Ferrillo, M., Ferro-Luzzi, M., Filippov, K., Fini, R. A., Fonte, P., Franco, C., Fraser, M., Fresa, R., Froeschl, R., Fukuda, T., Galati, G., Gall, J., Gatignon, L., Gavrilov, G., Gentile, V., Goddard, B., Golinka-Bezshyyko, L., Golovatiuk, A., Golovtsov, V., Golubkov, D., Golutvin, A., Gorbounov, P., Gorbunov, D., Gorbunov, S., Gorkavenko, V., Gorshenkov, M., Grachev, V., Grandchamp, A. L., Graverini, E., Grenard, J. -L., Grenier, D., Grichine, V., Gruzinskii, N., Guler, A. M., Guz, Yu., Haefeli, G. J., Hagner, C., Hakobyan, H., Harris, I. W., van Herwijnen, E., Hessler, C., Hollnagel, A., Hosseini, B., Hushchyn, M., Iaselli, G., Iuliano, A., Jacobsson, R., Joković, D., Jonker, M., Kadenko, I., Kain, V., Kaiser, B., Kamiscioglu, C., Karpenkov, D., Kershaw, K., Khabibullin, M., Khalikov, E., Khaustov, G., Khoriauli, G., Khotyantsev, A., Kim, Y. G., Kim, V., Kitagawa, N., Ko, J. -W., Kodama, K., Kolesnikov, A., Kolev, D. I., Kolosov, V., Komatsu, M., Kono, A., Konovalova, N., Kormannshaus, S., Korol, I., Korol'ko, I., Korzenev, A., Kostyukhin, V., Platia, E. Koukovini, Kovalenko, S., Krasilnikova, I., Kudenko, Y., Kurbatov, E., Kurbatov, P., Kurochka, V., Kuznetsova, E., Lacker, H. M., Lamont, M., Lanfranchi, G., Lantwin, O., Lauria, A., Lee, K. S., Lee, K. Y., Lévy, J. -M., Loschiavo, V. P., Lopes, L., Sola, E. Lopez, Lyubovitskij, V., Maalmi, J., Magnan, A. -M., Maleev, V., Malinin, A., Manabe, Y., Managadze, A. K., Manfredi, M., Marsh, S., Marshall, A. M., Mefodev, A., Mermod, P., Miano, A., Mikado, S., Mikhaylov, Yu., Milstead, D. A., Mineev, O., Montanari, A., Montesi, M. C., Morishima, K., Movchan, S., Muttoni, Y., Naganawa, N., Nakamura, M., Nakano, T., Nasybulin, S., Ninin, P., Nishio, A., Novikov, A., Obinyakov, B., Ogawa, S., Okateva, N., Opitz, B., Osborne, J., Ovchynnikov, M., Owtscharenko, N., Owen, P. H., Pacholek, P., Paoloni, A., Park, B. D., Pastore, A., Patel, M., Pereyma, D., Perillo-Marcone, A., Petkov, G. L., Petridis, K., Petrov, A., Podgrudkov, D., Poliakov, V., Polukhina, N., Prieto, J. Prieto, Prokudin, M., Prota, A., Quercia, A., Rademakers, A., Rakai, A., Ratnikov, F., Rawlings, T., Redi, F., Ricciardi, S., Rinaldesi, M., Rodin, Volodymyr, Rodin, Viktor, Robbe, P., Cavalcante, A. B. Rodrigues, Roganova, T., Rokujo, H., Rosa, G., Rovelli, T., Ruchayskiy, O., Ruf, T., Samoylenko, V., Samsonov, V., Galan, F. Sanchez, Diaz, P. Santos, Ull, A. Sanz, Saputi, A., Sato, O., Savchenko, E. S., Schliwinski, J. S., Schmidt-Parzefall, W., Serra, N., Sgobba, S., Shadura, O., Shakin, A., Shaposhnikov, M., Shatalov, P., Shchedrina, T., Shchutska, L., Shevchenko, V., Shibuya, H., Shirobokov, S., Shustov, A., Silverstein, S. B., Simone, S., Simoniello, R., Skorokhvatov, M., Smirnov, S., Sohn, J. Y., Sokolenko, A., Solodko, E., Starkov, N., Stoel, L., Stramaglia, M. E., Sukhonos, D., Suzuki, Y., Takahashi, S., Tastet, J. L., Teterin, P., Naing, S. Than, Timiryasov, I., Tioukov, V., Tommasini, D., Torii, M., Tosi, N., Treille, D., Tsenov, R., Ulin, S., Ursov, E., Ustyuzhanin, A., Uteshev, Z., Uvarov, L., Vankova-Kirilova, G., Vannucci, F., Venturi, V., Vilchinski, S., Vincke, Heinz, Vincke, Helmut, Visone, C., Vlasik, K., Volkov, A., Voronkov, R., van Waasen, S., Wanke, R., Wertelaers, P., Williams, O., Woo, J. -K., Wurm, M., Xella, S., Yilmaz, D., Yilmazer, A. U., Yoon, C. S., Zaytsev, Yu., Zelenov, A., and Zimmerman, J.
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High Energy Physics - Experiment - Abstract
Dark photons are hypothetical massive vector particles that could mix with ordinary photons. The simplest theoretical model is fully characterised by only two parameters: the mass of the dark photon m$_{\gamma^{\mathrm{D}}}$ and its mixing parameter with the photon, $\varepsilon$. The sensitivity of the SHiP detector is reviewed for dark photons in the mass range between 0.002 and 10 GeV. Different production mechanisms are simulated, with the dark photons decaying to pairs of visible fermions, including both leptons and quarks. Exclusion contours are presented and compared with those of past experiments. The SHiP detector is expected to have a unique sensitivity for m$_{\gamma^{\mathrm{D}}}$ ranging between 0.8 and 3.3$^{+0.2}_{-0.5}$ GeV, and $\varepsilon^2$ ranging between $10^{-11}$ and $10^{-17}$.
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- 2020
- Full Text
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27. SND@LHC
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SHiP Collaboration, Ahdida, C., Akmete, A., Albanese, R., Alexandrov, A., Andreini, M., Anokhina, A., Aoki, S., Arduini, G., Atkin, E., Azorskiy, N., Back, J. J., Bagulya, A., Santos, F. Baaltasar Dos, Baranov, A., Bardou, F., Barker, G. J., Battistin, M., Bauche, J., Bay, A., Bayliss, V., Bencivenni, G., Berdnikov, A. Y., Berdnikov, Y. A., Bertani, M., Bestmann, P., Betancourt, C., Bezshyiko, I., Bezshyyko, O., Bick, D., Bieschke, S., Blanco, A., Boehm, J., Bogomilov, M., Boiarska, I., Bondarenko, K., Bonivento, W. M., Borburgh, J., Boyarsky, A., Brenner, R., Breton, D., Buonocore, L. R., Büscher, V., Buonaura, A., Buontempo, S., Cadeddu, S., Calcaterra, A., Calviani, M., Campanelli, M., Canale, V., Casolino, M., Cerutti, F., Charitonidis, N., Chau, P., Chauveau, J., Chepurnov, A., Chernyavskiy, M., Choi, K. -Y., Chumakov, A., Ciambrone, P., Cicero, V., Congedo, L., Cornelis, K., Cristinziani, M., Crupano, A., Dallavalle, G. M., Datwyler, A., D'Ambrosio, N., D'Appollonio, G., de Asmundis, R., D'Archiac, P. T. De Bryas Dexmiers, Saraiva, J. De Carvalho, De Lellis, G., de Magistris, M., De Roeck, A., De Serio, M., De Simone, D., Dedenko, L., Dergachev, P., Di Crescenzo, A., Di Giulio, L., Di Marco, N., Dib, C., Dijkstra, H., Dmitrenko, V., Dmitrievskiy, S., Dougherty, L. A., Dolmatov, A., Domenici, D., Donskov, S., Drohan, V., Dubreuil, A., Durhan, O., Ehlert, M., Elikkaya, E., Enik, T., Etenko, A., Fabbri, F., Fedin, O., Fedotovs, F., Felici, G., Ferrillo, M., Ferro-Luzzi, M., Filippov, K., Fini, R. A., Fonte, P., Franco, C., Fraser, M., Fresa, R., Froeschl, R., Fukuda, T., Galati, G., Gall, J., Gatignon, L., Gavrilov, G., Gentile, V., Goddard, B., Golinka-Bezshyyko, L., Golovatiuk, A., Golubkov, D., Golutvin, A., Gorbounov, P., Gorbunov, D., Gorbunov, S., Gorkavenko, V., Gorshenkov, M., Grachev, V., Grandchamp, A. L., Graverini, E., Grenard, J. -L., Grenier, D., Grichine, V., Gruzinskii, N., Guler, A. M., Guz, Yu., Haefeli, G. J., Hagner, C., Hakobyan, H., Harris, I. W., van Herwijnen, E., Hessler, C., Hollnagel, A., Hosseini, B., Hushchyn, M., Iaselli, G., Iengo, P., Iuliano, A., Jacobsson, R., Joković, D., Jonker, M., Kadenko, I., Kain, V., Kaiser, B., Kamiscioglu, C., Karpenkov, D., Kershaw, K., Khabibullin, M., Khalikov, E., Khaustov, G., Khoriauli, G., Khotyantsev, A., Kim, Y. G., Kim, V., Kitagawa, N., Ko, J. -W., Kodama, K., Kolesnikov, A., Kolev, D. I., Kolosov, V., Komatsu, M., Kono, A., Konovalova, N., Kormannshaus, S., Korol, I., Korol'ko, I., Korzenev, A., Kostyukhin, V., Platia, E. Koukovini, Kovalenko, S., Krasilnikova, I., Kudenko, Y., Kurbatov, E., Kurbatov, P., Kurochka, V., Kuznetsova, E., Lacker, H. M., Lamont, M., Lanfranchi, G., Lantwin, O., Lauria, A., Lee, K. S., Lee, K. Y., Lévy, J. -M., Loschiavo, V. P., Lopes, L., Sola, E. Lopez, Lyubovitskij, V., Maalmi, J., Magnan, A., Maleev, V., Malinin, A., Manabe, Y., Managadze, A. K., Manfredi, M., Marsh, S., Marshall, A. M., Mefodev, A., Mermod, P., Miano, A., Mikado, S., Mikhaylov, Yu., Milstead, D. A., Mineev, O., Montanari, A., Montesi, M. C., Morishima, K., Movchan, S., Muttoni, Y., Naganawa, N., Nasybulin, S., Ninin, P., Nishio, A., Novikov, A., Obinyakov, B., Ogawa, S., Okateva, N., Opitz, B., Osborne, J., Ovchynnikov, M., Owtscharenko, N., Owen, P. H., Pacholek, P., Paoloni, A., Park, B. D., Passeggio, G., Pastore, A., Patel, M., Pereyma, D., Perillo-Marcone, A., Petkov, G. L., Petridis, K., Petrov, A., Podgrudkov, D., Poliakov, V., Polukhina, N., Prieto, J. Prieto, Prokudin, M., Prota, A., Quercia, A., Rademakers, A., Rakai, A., Ratnikov, F., Rawlings, T., Redi, F., Ricciardi, S., Rinaldesi, M., Rodin, Volodymyr, Rodin, Viktor, Robbe, P., Cavalcante, A. B. Rodrigues, Roganova, T., Rokujo, H., Rosa, G., Rovelli, T., Ruchayskiy, O., Ruf, T., Gilarte, M. Sabate, Samoylenko, V., Samsonov, V., Galan, F. Sanchez, Diaz, P. Santos, Ull, A. Sanz, Saputi, A., Savchenko, E. S., Schliwinski, J. S., Schmidt-Parzefall, W., Schneider, O., Sekhniaidze, G., Serra, N., Sgobba, S., Shadura, O., Shakin, A., Shaposhnikov, M., Shatalov, P., Shchedrina, T., Shchutska, L., Shevchenko, V., Shibuya, H., Shihora, L., Shirobokov, S., Shustov, A., Silverstein, S. B., Simone, S., Simoniello, R., Skorokhvatov, M., Smirnov, S., Sohn, J. Y., Sokolenko, A., Solodko, E., Starkov, N., Stoel, L., Stramaglia, M. E., Strekalina, D., Sukhonos, D., Suzuki, Y., Takahashi, S., Tastet, J. L., Teterin, P., Naing, S. Than, Timiryasov, I., Tioukov, V., Tommasini, D., Torii, M., Tosi, N., Tramontano, F., Treille, D., Tsenov, R., Ulin, S., Ursov, E., Ustyuzhanin, A., Uteshev, Z., Vankova-Kirilova, G., Vannucci, F., Vendeuvre, C., Venturi, V., Vilchinski, S., Vincke, Heinz, Vincke, Helmut, Visone, C., Vlasik, K., Volkov, A., Voronkov, R., van Waasen, S., Wanke, R., Wertelaers, P., Williams, O., Woo, J. -K., Wurm, M., Xella, S., Yilmaz, D., Yilmazer, A. U., Yoon, C. S., Zaytsev, Yu., and Zimmerman, J.
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Physics - Instrumentation and Detectors ,High Energy Physics - Experiment - Abstract
We propose to build and operate a detector that, for the first time, will measure the process $pp\to\nu X$ at the LHC and search for feebly interacting particles (FIPs) in an unexplored domain. The TI18 tunnel has been identified as a suitable site to perform these measurements due to very low machine-induced background. The detector will be off-axis with respect to the ATLAS interaction point (IP1) and, given the pseudo-rapidity range accessible, the corresponding neutrinos will mostly come from charm decays: the proposed experiment will thus make the first test of the heavy flavour production in a pseudo-rapidity range that is not accessible by the current LHC detectors. In order to efficiently reconstruct neutrino interactions and identify their flavour, the detector will combine in the target region nuclear emulsion technology with scintillating fibre tracking layers and it will adopt a muon identification system based on scintillating bars that will also play the role of a hadronic calorimeter. The time of flight measurement will be achieved thanks to a dedicated timing detector. The detector will be a small-scale prototype of the scattering and neutrino detector (SND) of the SHiP experiment: the operation of this detector will provide an important test of the neutrino reconstruction in a high occupancy environment., Comment: Letter of Intent
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- 2020
28. First observation of a tau neutrino charged current interaction with charm production in the Opera experiment
- Author
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Agafonova, N., Alexandrov, A., Anokhina, A., Aoki, S., Ariga, A., Ariga, T., Bertolin, A., Bozza, C., Brugnera, R., Buonaura, A., Buontempo, S., Chernyavskiy, M., Chukanov, A., Consiglio, L., D'Ambrosio, N., De Lellis, G., De Serio, M., Sanchez, P. del Amo, Di Crescenzo, A., Di Ferdinando, D., Di Marco, N., Dmitrievsky, S., Dracos, M., Duchesneau, D., Dusini, S., Dzhatdoev, T., Ebert, J., Ereditato, A., Fini, R. A., Fornari, F., Fukuda, T., Galati, G., Garfagnini, A., Gentile, V., Goldberg, J., Gorbunov, S., Gornushkin, Y., Grella, G., Guler, A. M., Gustavino, C., Hagner, C., Hara, T., Hayakawa, T., Hollnagel, A., Ishiguro, K., Iuliano, A., ić, K. Jakovč, Jollet, C., Kamiscioglu, C., Kamiscioglu, M., Kim, S. H., Kitagawa, N., ek, B. Klič, Kodama, K., Komatsu, M., Kose, U., Kreslo, I., Laudisio, F., Lauria, A., Longhin, A., Loverre, P., Malgin, A., Mandrioli, G., Matsuo, T., Matveev, V., Mauri, N., Medinaceli, E., Meregaglia, A., Mikado, S., Miyanishi, M., Mizutani, F., Monacelli, P., Montesi, M. C., Morishima, K., Muciaccia, M. T., Naganawa, N., Naka, T., Nakamura, M., Nakano, T., Niwa, K., Ogawa, S., Okateva, N., Ozaki, K., Paoloni, A., Paparella, L., Park, B. D., Pasqualini, L., Pastore, A., Patrizii, L., Pessard, H., Podgrudkov, D., Polukhina, N., Pozzato, M., Pupilli, F., Roda, M., Roganova, T., Rokujo, H., Rosa, G., Ryazhskaya, O., Sato, O., Schembri, A., Shakiryanova, I., Shchedrina, T., Shibayama, E., Shibuya, H., Shiraishi, T., Simone, S., Sirignano, C., Sirri, G., Sotnikov, A., Spinetti, M., Stanco, L., Starkov, N., Stellacci, S. M., ević, M. Stipč, Strolin, P., Takahashi, S., Tenti, M., Terranova, F., Tioukov, V., Vasina, S., Vilain, P., Voevodina, E., Votano, L., Vuilleumier, J. L., Wilquet, G., and Yoon, C. S.
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High Energy Physics - Experiment - Abstract
An event topology with two secondary vertices compatible with the decay of short-lived particles was found in the analysis of neutrino interactions in the Opera target. The observed topology is compatible with tau neutrino charged current (CC) interactions with charm production and neutrino neutral current (NC) interactions with $c\overline{c}$ pair production. However, other processes can mimic this topology. A dedicated analysis was implemented to identify the underlying process. A Monte Carlo simulation was developed and complementary procedures were introduced in the kinematic reconstruction. A multivariate analysis technique was used to achieve an optimal separation of signal from background. Most likely, this event is a $\nu_{\tau}$ CC interaction with charm production, the tau and charm particle decaying into 1 prong and 2 prongs, respectively. The significance of this observation is evaluated., Comment: 10 pages, 7 figures; Editors: Marco Roda, Chiara Sirignano and Gabriele Sirri
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- 2019
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29. From Resilience Engineering to Resilient Performance
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Hollnagel, Erik, Nemeth, Christopher P., Nemeth, Christopher P., editor, and Hollnagel, Erik, editor
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- 2022
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- View/download PDF
30. ATTENTION-BASED VIEW: PAST, PRESENT AND FUTURE/VISAO BASEADA NA ATENCAO: PASSADO, PRESENTE E FUTURO/VISION BASADA EN LA ATENCION: PASADO, PRESENTE Y FUTURO
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Bueno, Ricardo Luiz Pereira, Hollnagel, Heloisa Candia, and Serra, Fernando Antonio Ribeiro
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- 2024
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31. Three-tiered approach for standard information requirements for polymers requiring registration under REACH
- Author
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Otte, Jens C., Hollnagel, Heli Miriam, Nagel, Christiane, Gerhardt, Renata Friederike, Wohlleben, Wendel, Vallotton, Nathalie, Schowanek, Diederik, Sanders, Gordon, Frasca, Joe M., Mahale, Tushar, Pemberton, Mark, Hidding, Bjoern, and Landsiedel, Robert
- Published
- 2023
- Full Text
- View/download PDF
32. Final results on neutrino oscillation parameters from the OPERA experiment in the CNGS beam
- Author
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OPERA Collaboration, Agafonova, N., Alexandrov, A., Anokhina, A., Aoki, S., Ariga, A., Ariga, T., Bertolin, A., Bozza, C., Brugnera, R., Buontempo, S., Chernyavskiy, M., Chukanov, A., Consiglio, L., D'Ambrosio, N., De Lellis, G., De Serio, M., Sanchez, P. del Amo, Di Crescenzo, A., Di Ferdinando, D., Di Marco, N., Dmitrievsky, S., Dracos, M., Duchesneau, D., Dusini, S., Dzhatdoev, T., Ebert, J., Ereditato, A., Fini, R. A., Fukuda, T., Galati, G., Garfagnini, A., Gentile, V., Goldberg, J., Gorbunov, S., Gornushkin, Y., Grella, G., Guler, A. M., Gustavino, C., Hagner, C., Hara, T., Hayakawa, T., Hollnagel, A., Ishiguro, K., Iuliano, A., Jakovcic, K., Jollet, C., Kamiscioglu, C., Kamiscioglu, M., Kim, S. H., Kitagawa, N., Klicek, B., Kodama, K., Komatsu, M., Kose, U., Kreslo, I., Laudisio, F., Lauria, A., Longhin, A., Loverre, P., Malgin, A., Mandrioli, G., Matsuo, T., Matveev, V., Mauri, N., Medinaceli, E., Meregaglia, A., Mikado, S., Miyanishi, M., Mizutani, F., Monacelli, P., Montesi, M. C., Morishima, K., Muciaccia, M. T., Naganawa, N., Naka, T., Nakamura, M., Nakano, T., Niwa, K., Ogawa, S., Okateva, N., Ozaki, K., Paoloni, A., Paparella, L., Park, B. D., Pasqualini, L., Pastore, A., Patrizii, L., Pessard, H., Podgrudkov, D., Polukhina, N., Pozzato, M., Pupilli, F., Roda, M., Roganova, T., Rokujo, H., Rosa, G., Ryazhskaya, O., Sato, O., Schembri, A., Shakiryanova, I., Shchedrina, T., Shibayama, E., Shibuya, H., Shiraishi, T., Simone, S., Sirignano, C., Sirri, G., Sotnikov, A., Spinetti, M., Stanco, L., Starkov, N., Stellacci, S. M., Stipcevic, M., Strolin, P., Takahashi, S., Tenti, M., Terranova, F., Tioukov, V., Tufanli, S., Vasina, S., Vilain, P., Voevodina, E., Votano, L., Vuilleumier, J. L., Wilquet, G., and Yoon, C. S.
- Subjects
High Energy Physics - Experiment ,Physics - Instrumentation and Detectors - Abstract
The OPERA experiment has conclusively observed the appearance of tau neutrinos in the muon neutrino CNGS beam. Exploiting the OPERA detector capabilities, it was possible to isolate high purity samples of $\nu_{e}$, $\nu_{\mu}$ and $\nu_{\tau}$ charged current weak neutrino interactions, as well as neutral current weak interactions. In this Letter, the full dataset is used for the first time to test the three-flavor neutrino oscillation model and to derive constraints on the existence of a light sterile neutrino within the framework of the $3+1$ neutrino model. For the first time, tau and electron neutrino appearance channels are jointly used to test the sterile neutrino hypothesis. A significant fraction of the sterile neutrino parameter space allowed by LSND and MiniBooNE experiments is excluded at 90% C.L. In particular, the best-fit values obtained by MiniBooNE combining neutrino and antineutrino data are excluded at 3.3 $\sigma$ significance., Comment: 7 pages, 4 figures; Editors: Budimir Kli\v{c}ek and Matteo Tenti
- Published
- 2019
- Full Text
- View/download PDF
33. Proof-of-principle measurements with a liquid-scintillator detector using wavelength-shifting optical modules
- Author
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Ehlert, M., Hollnagel, A., Korol, I., Korzenev, A., Lacker, H., Mermod, P., Schliwinski, J., Shihora, L., Venkova, P., and Wurm, M.
- Subjects
Physics - Instrumentation and Detectors ,High Energy Physics - Experiment - Abstract
Based on test-beam measurements, we study the response of a liquid-scintillator detector equipped with wavelength-shifting optical modules, that are proposed e.g. for the IceCube experiment and the SHiP experiment, and adiabatic light guides that are viewed either by a photomultiplier tube or by an array of silicon photomultipliers. We report on the efficiency, the time resolution and the detector response to different particle types and point out potential ways to improve the detector performance.
- Published
- 2018
- Full Text
- View/download PDF
34. Assessment of using hydrogen in gas distribution grids
- Author
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Giehl, Johannes, Hollnagel, Jeremias, and Müller-Kirchenbauer, Joachim
- Published
- 2023
- Full Text
- View/download PDF
35. Visualising for Safety or Visualisation of Safety?
- Author
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Hollnagel, Erik, primary
- Published
- 2023
- Full Text
- View/download PDF
36. Systemic Potentials for Resilient Performance
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Hollnagel, Erik, Matos, Florinda, editor, Selig, Paulo Maurício, editor, and Henriqson, Eder, editor
- Published
- 2022
- Full Text
- View/download PDF
37. Latest results of the OPERA experiment on nu-tau appearance in the CNGS neutrino beam
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Agafonova, N., Alexandrov, A., Anokhina, A., Aoki, S., Ariga, A., Ariga, T., Bertolin, A., Bozza, C., Brugnera, R., Buonaura, A., Buontempo, S., Chernyavskiy, M., Chukanov, A., Consiglio, L., D'Ambrosio, N., De Lellis, G., De Serio, M., Sanchez, P. del Amo, Di Crescenzo, A., Di Ferdinando, D., Di Marco, N., Dmitrievsky, S., Dracos, M., Duchesneau, D., Dusini, S., Dzhatdoev, T., Ebert, J., Ereditato, A., Favier, J., Fini, R. A., Fornari, F., Fukuda, T., Galati, G., Garfagnini, A., Gentile, V., Goldberg, J., Gorbunov, S., Gornushkin, Y., Grella, G., Guler, A. M., Gustavino, C., Hagner, C., Hara, T., Hayakawa, T., Hollnagel, A., Ishiguro, K., Iuliano, A., Jakovcic, K., Jollet, C., Kamiscioglu, C., Kamiscioglu, M., Kim, S. H., Kitagawa, N., Klicek, B., Kodama, K., Komatsu, M., Kose, U., Kreslo, I., Laudisio, F., Lauria, A., Longhin, A., Loverre, P., Malenica, M., Malgin, A., Mandrioli, G., Matsuo, T., Matveev, V., Mauri, N., Medinaceli, E., Meregaglia, A., Mikado, S., Miyanishi, M., Mizutani, F., Monacelli, P., Montesi, M. C., Morishima, K., Muciaccia, M. T., Naganawa, N., Naka, T., Nakamura, M., Nakano, T., Niwa, K., Ogawa, S., Olchevsky, A., Okateva, N., Ozaki, K., Paoloni, A., Paparella, L., Park, B. D., Pasqualini, L., Pastore, A., Patrizii, L., Pessard, H., Pistillo, C., Podgrudkov, D., Polukhina, N., Pozzato, M., Pupilli, F., Roda, M., Roganova, T., Rokujo, H., Rosa, G., Ryazhskaya, O., Sadovsky, A., Sato, O., Schembri, A., Shakiryanova, I., Shchedrina, T., Shibayama, E., Shibuya, H., Shiraishi, T., Simone, S., Sirignano, C., Sirri, G., Sotnikov, A., Spinetti, M., Stanco, L., Starkov, N., Stellacci, S. M., Stipcevic, M., Strolin, P., Takahashi, S., Tenti, M., Terranova, F., Tioukov, V., Tufanli, S., Ustyuzhanin, A., Vasina, S., Vilain, P., Voevodina, E., Votano, L., Vuilleumier, J. L., Wilquet, G., Wonsak, B., and Yoon, C. S.
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High Energy Physics - Experiment ,Physics - Instrumentation and Detectors - Abstract
OPERA is a long-baseline experiment designed to search for $\nu_{\mu}\to\nu_{\tau}$ oscillations in appearance mode. It was based at the INFN Gran Sasso laboratory (LNGS) and took data from 2008 to 2012 with the CNGS neutrino beam from CERN. After the discovery of $\nu_\tau$ appearance in 2015, with $5.1\sigma$ significance, the criteria to select $\nu_\tau$ candidates have been extended and a multivariate approach has been used for events identification. In this way the statistical uncertainty in the measurement of the oscillation parameters and of $\nu_\tau$ properties has been improved. Results are reported., Comment: 7 pages, 1 figure, conference: The 15th International Workshop on Tau Lepton Physics (tau2018)AB
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- 2018
38. Measurement of the cosmic ray muon flux seasonal variation with the OPERA detector
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Agafonova, N., Alexandrov, A., Anokhina, A., Aoki, S., Ariga, A., Ariga, T., Bertolin, A., Bozza, C., Brugnera, R., Buonaura, A., Buontempo, S., Chernyavskiy, M., Chukanov, A., Consiglio, L., D'Ambrosio, N., De Lellis, G., De Serio, M., Sanchez, P. del Amo, Di Crescenzo, A., Di Ferdinando, D., Di Marco, N., Dmitrievsky, S., Dracos, M., Duchesneau, D., Dusini, S., Dzhatdoev, T., Ebert, J., Ereditato, A., Fini, R. A., Fornari, F., Fukuda, T., Galati, G., Garfagnini, A., Gentile, V., Goldberg, J., Gorbunov, S., Gornushkin, Y., Grella, G., Guler, A. M., Gustavino, C., Hagner, C., Hara, T., Hayakawa, T., Hollnagel, A., Ishiguro, K., Iuliano, A., Jakovčić, K., Jollet, C., Kamiscioglu, C., Kamiscioglu, M., Kim, S. H., Kitagawa, N., Kliček, B., Kodama, K., Komatsu, M., Kose, U., Kreslo, I., Laudisio, F., Lauria, A., Ljubičić, A., Longhin, A., Loverre, P., Malgin, A., Mandrioli, G., Matsuo, T., Matveev, V., Mauri, N., Medinaceli, E., Meregaglia, A., Mikado, S., Miyanishi, M., Mizutani, F., Monacelli, P., Montesi, M. C., Morishima, K., Muciaccia, M. T., Naganawa, N., Naka, T., Nakamura, M., Nakano, T., Niwa, K., Ogawa, S., Okateva, N., Ozaki, K., Paoloni, A., Paparella, L., Park, B. D., Pasqualini, L., Pastore, A., Patrizii, L., Pessard, H., Podgrudkov, D., Polukhina, N., Pozzato, M., Pupilli, F., Roda, M., Roganova, T., Rokujo, H., Rosa, G., Ryazhskaya, O., Sato, O., Schembri, A., Shakiryanova, I., Shchedrina, T., Shibayama, E., Shibuya, H., Shiraishi, T., Simone, S., Sirignano, C., Sirri, G., Sotnikov, A., Spinetti, M., Stanco, L., Starkov, N., Stellacci, S. M., Stipčević, M., Strolin, P., Takahashi, S., Tenti, M., Terranova, F., Tioukov, V., Vasina, S., Vilain, P., Voevodina, E., Votano, L., Vuilleumier, J. L., Wilquet, G., and Yoon, C. S.
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High Energy Physics - Experiment ,Physics - Instrumentation and Detectors - Abstract
The OPERA experiment discovered muon neutrino into tau neutrino oscillations in appearance mode, detecting tau leptons by means of nuclear emulsion films. The apparatus was also endowed with electronic detectors with tracking capability, such as scintillator strips and resistive plate chambers. Because of its location, in the underground Gran Sasso laboratory, under 3800 m.w.e., the OPERA detector has also been used as an observatory for TeV muons produced by cosmic rays in the atmosphere. In this paper the measurement of the single muon flux modulation and of its correlation with the seasonal variation of the atmospheric temperature are reported.
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- 2018
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39. Final results of the OPERA experiment on $\nu_\tau$ appearance in the CNGS beam
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OPERA Collaboration, Agafonova, N., Alexandrov, A., Anokhina, A., Aoki, S., Ariga, A., Ariga, T., Bertolin, A., Bozza, C., Brugnera, R., Buonaura, A., Buontempo, S., Chernyavskiy, M., Chukanov, A., Consiglio, L., D'Ambrosio, N., De Lellis, G., De Serio, M., Sanchez, P. del Amo, Di Crescenzo, A., Di Ferdinando, D., Di Marco, N., Dmitrievsky, S., Dracos, M., Duchesneau, D., Dusini, S., Dzhatdoev, T., Ebert, J., Ereditato, A., Favier, J., Fini, R. A., Fornari, F., Fukuda, T., Galati, G., Garfagnini, A., Gentile, V., Goldberg, J., Gornushkin, Y., Gorbunov, S., Grella, G., Guler, A. M., Gustavino, C., Hagner, C., Hara, T., Hayakawa, T., Hollnagel, A., Ishiguro, K., Iuliano, A., Jakovcic, K., Jollet, C., Kamiscioglu, C., Kamiscioglu, M., Kim, S. H., Kitagawa, N., Klicek, B., Kodama, K., Komatsu, M., Kose, U., Kreslo, I., Laudisio, F., Lauria, A., Ljubicic, A., Longhin, A., Loverre, P., Malgin, A., Malenica, M., Mandrioli, G., Matsuo, T., Matveev, V., Mauri, N., Medinaceli, E., Meregaglia, A., Mikado, S., Miyanishi, M., Mizutani, F., Monacelli, P., Montesi, M. C., Morishima, K., Muciaccia, M. T., Naganawa, N., Naka, T., Nakamura, M., Nakano, T., Niwa, K., Okateva, N., Olchevsky, A., Ogawa, S., Ozaki, K., Paoloni, A., Paparella, L., Park, B. D., Pasqualini, L., Pastore, A., Patrizii, L., Pessard, H., Pistillo, C., Podgrudkov, D., Polukhina, N., Pozzato, M., Pupilli, F., Roda, M., Roganova, T., Rokujo, H., Rosa, G., Ryazhskaya, O., Sadovsky, A., Sato, O., Schembri, A., Shakiryanova, I., Shchedrina, T., Shibuya, H., Shibayama, E., Shiraishi, T., Simone, S., Sirignano, C., Sirri, G., Sotnikov, A., Spinetti, M., Stanco, L., Starkov, N., Stellacci, S. M., Stipcevic, M., Strolin, P., Takahashi, S., Tenti, M., Terranova, F., Tioukov, V., Tufanli, S., Ustyuzhanin, A., Vasina, S., Vilain, P., Voevodina, E., Votano, L., Vuilleumier, J. L., Wilquet, G., Wonsak, B., and Yoon, C. S.
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High Energy Physics - Experiment - Abstract
The OPERA experiment was designed to study $\nu_\mu\to\nu_\tau$ oscillations in appearance mode in the CNGS neutrino beam. In this letter we report the final analysis of the full data sample collected between 2008 and 2012, corresponding to $17.97\cdot 10^{19}$ protons on target. Selection criteria looser than in previous analyses have produced ten $\nu_\tau$ candidate events, thus reducing the statistical uncertainty in the measurement of the oscillation parameters and of $\nu_\tau$ properties. A multivariate approach for event identification has been applied to the candidate events and the discovery of $\nu_\tau$ appearance is confirmed with an improved significance level of 6.1 $\sigma$. $\Delta m^2_{23}$ has been measured, in appearance mode, with an accuracy of 20%. The measurement of $\nu_\tau$ CC cross-section, for the first time with a negligible contamination from $\bar{\nu}_\tau$, and the first direct observation of the $\nu_\tau$ lepton number are also reported., Comment: 7 pages, 3 figures
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- 2018
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40. Final results of the search for $\nu_{\mu} \to \nu_{e}$ oscillations with the OPERA detector in the CNGS beam
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OPERA Collaboration, Agafonova, N., Aleksandrov, A., Anokhina, A., Aoki, S., Ariga, A., Ariga, T., Bertolin, A., Bozza, C., Brugnera, R., Buonaura, A., Buontempo, S., Chernyavskiy, M., Chukanov, A., Consiglio, L., D'Ambrosio, N., De Lellis, G., De Serio, M., Sanchez, P. del Amo, Di Crescenzo, A., Di Ferdinando, D., Di Marco, N., Dmitrievsky, S., Dracos, M., Duchesneau, D., Dusini, S., Dzhatdoev, T., Ebert, J., Ereditato, A., Favier, J., Fini, R. A., Fornari, F., Fukuda, T., Galati, G., Garfagnini, A., Gentile, V., Goldberg, J., Gornushkin, Y., Gorbunov, S., Grella, G., Guler, A. M., Gustavino, C., Hagner, C., Hara, T., Hayakawa, T., Hollnagel, A., Hosseini, B., Ishiguro, K., Iuliano, A., Jakovcic, K., Jollet, C., Kamiscioglu, C., Kamiscioglu, M., Kim, S. H., Kitagawa, N., Klicek, B., Kodama, K., Komatsu, M., Kose, U., Kreslo, I., Laudisio, F., Lauria, A., Ljubicic, A., Longhin, A., Loverre, P., Malgin, A., Malenica, M., Mandrioli, G., Matsuo, T., Matveev, V., Mauri, N., Medinaceli, E., Meisel, F., Meregaglia, A., Mikado, S., Miyanishi, M., Mizutani, F., Monacelli, P., Montesi, M. C., Morishima, K., Muciaccia, M. T., Naganawa, N., Naka, T., Nakamura, M., Nakano, T., Niwa, K., Okateva, N., Ogawa, S., Ozaki, K., Paoloni, A., Paparella, L., Park, B. D., Pasqualini, L., Pastore, A., Patrizii, L., Pessard, H., Podgrudkov, D., Polukhina, N., Pozzato, M., Pupilli, F., Roda, M., Roganova, T., Rokujo, H., Rosa, G., Ryazhskaya, O., Sato, O., Schembri, A., Shakiryanova, I., Shchedrina, T., Shibuya, H., Shibayama, E., Shiraishi, T., Simone, S., Sirignano, C., Sirri, G., Sotnikov, A., Spinetti, M., Stanco, L., Starkov, N., Stellacci, S. M., Stipcevic, M., Strolin, P., Takahashi, S., Tenti, M., Terranova, F., Tioukov, V., Vasina, S., Vilain, P., Voevodina, E., Votano, L., Vuilleumier, J. L., Wilquet, G., and Yoon, C. S.
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High Energy Physics - Experiment ,Physics - Instrumentation and Detectors - Abstract
The OPERA experiment has discovered the tau neutrino appearance in the CNGS muon neutrino beam, in agreement with the 3 neutrino flavour oscillation hypothesis. The OPERA neutrino interaction target, made of Emulsion Cloud Chamber, was particularly efficient in the reconstruction of electromagnetic showers. Moreover, thanks to the very high granularity of the emulsion films, showers induced by electrons can be distinguished from those induced by $\pi^0$s, thus allowing the detection of charged current interactions of electron neutrinos. In this paper the results of the search for electron neutrino events using the full dataset are reported. An improved method for the electron neutrino energy estimation is exploited. Data are compatible with the 3 neutrino flavour mixing model expectations and are used to set limits on the oscillation parameters of the 3+1 neutrino mixing model, in which an additional mass eigenstate $m_{4}$ is introduced. At high $\Delta m^{2}_{41}$ $( \gtrsim 0.1~\textrm{eV}^{2})$, an upper limit on $\sin^2 2\theta_{\mu e}$ is set to 0.021 at 90% C.L. and $\Delta m^2_{41} \gtrsim 4 \times 10^{-3}~\textrm{eV}^{2}$ is excluded for maximal mixing in appearance mode., Comment: Editors: M. Tenti and S. Vasina
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- 2018
41. The SHiP experiment at the proposed CERN SPS Beam Dump Facility
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C. Ahdida, A. Akmete, R. Albanese, J. Alt, A. Alexandrov, A. Anokhina, S. Aoki, G. Arduini, E. Atkin, N. Azorskiy, J. J. Back, A. Bagulya, F. Baaltasar Dos Santos, A. Baranov, F. Bardou, G. J. Barker, M. Battistin, J. Bauche, A. Bay, V. Bayliss, A. Y. Berdnikov, Y. A. Berdnikov, C. Betancourt, I. Bezshyiko, O. Bezshyyko, D. Bick, S. Bieschke, A. Blanco, J. Boehm, M. Bogomilov, I. Boiarska, K. Bondarenko, W. M. Bonivento, J. Borburgh, A. Boyarsky, R. Brenner, D. Breton, A. Brignoli, V. Büscher, A. Buonaura, S. Buontempo, S. Cadeddu, M. Calviani, M. Campanelli, M. Casolino, N. Charitonidis, P. Chau, J. Chauveau, A. Chepurnov, M. Chernyavskiy, K.-Y. Choi, A. Chumakov, M. Climescu, A. Conaboy, L. Congedo, K. Cornelis, M. Cristinziani, A. Crupano, G. M. Dallavalle, A. Datwyler, N. D’Ambrosio, G. D’Appollonio, R. de Asmundis, J. De Carvalho Saraiva, G. De Lellis, M. de Magistris, A. De Roeck, M. De Serio, D. De Simone, L. Dedenko, P. Dergachev, A. Di Crescenzo, L. Di Giulio, C. Dib, H. Dijkstra, V. Dmitrenko, L. A. Dougherty, A. Dolmatov, S. Donskov, V. Drohan, A. Dubreuil, O. Durhan, M. Ehlert, E. Elikkaya, T. Enik, A. Etenko, O. Fedin, F. Fedotovs, M. Ferrillo, M. Ferro-Luzzi, K. Filippov, R. A. Fini, H. Fischer, P. Fonte, C. Franco, M. Fraser, R. Fresa, R. Froeschl, T. Fukuda, G. Galati, J. Gall, L. Gatignon, G. Gavrilov, V. Gentile, B. Goddard, L. Golinka-Bezshyyko, A. Golovatiuk, V. Golovtsov, D. Golubkov, A. Golutvin, P. Gorbounov, D. Gorbunov, S. Gorbunov, V. Gorkavenko, M. Gorshenkov, V. Grachev, A. L. Grandchamp, E. Graverini, J.-L. Grenard, D. Grenier, V. Grichine, N. Gruzinskii, A. M. Guler, Yu. Guz, G. J. Haefeli, C. Hagner, H. Hakobyan, I. W. Harris, E. van Herwijnen, C. Hessler, A. Hollnagel, B. Hosseini, M. Hushchyn, G. Iaselli, A. Iuliano, R. Jacobsson, D. Joković, M. Jonker, I. Kadenko, V. Kain, B. Kaiser, C. Kamiscioglu, D. Karpenkov, K. Kershaw, M. Khabibullin, E. Khalikov, G. Khaustov, G. Khoriauli, A. Khotyantsev, Y. G. Kim, V. Kim, N. Kitagawa, J.-W. Ko, K. Kodama, A. Kolesnikov, D. I. Kolev, V. Kolosov, M. Komatsu, A. Kono, N. Konovalova, S. Kormannshaus, I. Korol, I. Korol’ko, A. Korzenev, E. Koukovini Platia, S. Kovalenko, I. Krasilnikova, Y. Kudenko, E. Kurbatov, P. Kurbatov, V. Kurochka, E. Kuznetsova, H. M. Lacker, M. Lamont, O. Lantwin, A. Lauria, K. S. Lee, K. Y. Lee, N. Leonardo, J.-M. Lévy, V. P. Loschiavo, L. Lopes, E. Lopez Sola, F. Lyons, V. Lyubovitskij, J. Maalmi, A.-M. Magnan, V. Maleev, A. Malinin, Y. Manabe, A. K. Managadze, M. Manfredi, S. Marsh, A. M. Marshall, A. Mefodev, P. Mermod, A. Miano, S. Mikado, Yu. Mikhaylov, A. Mikulenko, D. A. Milstead, O. Mineev, M. C. Montesi, K. Morishima, S. Movchan, Y. Muttoni, N. Naganawa, M. Nakamura, T. Nakano, S. Nasybulin, P. Ninin, A. Nishio, B. Obinyakov, S. Ogawa, N. Okateva, J. Osborne, M. Ovchynnikov, N. Owtscharenko, P. H. Owen, P. Pacholek, B. D. Park, A. Pastore, M. Patel, D. Pereyma, A. Perillo-Marcone, G. L. Petkov, K. Petridis, A. Petrov, D. Podgrudkov, V. Poliakov, N. Polukhina, J. Prieto Prieto, M. Prokudin, A. Prota, A. Quercia, A. Rademakers, A. Rakai, F. Ratnikov, T. Rawlings, F. Redi, A. Reghunath, S. Ricciardi, M. Rinaldesi, Volodymyr Rodin, Viktor Rodin, P. Robbe, A. B. Rodrigues Cavalcante, T. Roganova, H. Rokujo, G. Rosa, O. Ruchayskiy, T. Ruf, V. Samoylenko, V. Samsonov, F. Sanchez Galan, P. Santos Diaz, A. Sanz Ull, O. Sato, E. S. Savchenko, J. S. Schliwinski, W. Schmidt-Parzefall, M. Schumann, N. Serra, S. Sgobba, O. Shadura, A. Shakin, M. Shaposhnikov, P. Shatalov, T. Shchedrina, L. Shchutska, V. Shevchenko, H. Shibuya, L. Shihora, S. Shirobokov, A. Shustov, S. B. Silverstein, S. Simone, R. Simoniello, M. Skorokhvatov, S. Smirnov, G. Soares, J. Y. Sohn, A. Sokolenko, E. Solodko, N. Starkov, L. Stoel, M. E. Stramaglia, D. Sukhonos, Y. Suzuki, S. Takahashi, J. L. Tastet, P. Teterin, S. Than Naing, I. Timiryasov, V. Tioukov, D. Tommasini, M. Torii, D. Treille, R. Tsenov, S. Ulin, E. Ursov, A. Ustyuzhanin, Z. Uteshev, L. Uvarov, G. Vankova-Kirilova, F. Vannucci, P. Venkova, V. Venturi, I. Vidulin, S. Vilchinski, Heinz Vincke, Helmut Vincke, C. Visone, K. Vlasik, A. Volkov, R. Voronkov, S. van Waasen, R. Wanke, P. Wertelaers, O. Williams, J.-K. Woo, M. Wurm, S. Xella, D. Yilmaz, A. U. Yilmazer, C. S. Yoon, Yu. Zaytsev, A. Zelenov, J. Zimmerman, and SHiP Collaboration
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Astrophysics ,QB460-466 ,Nuclear and particle physics. Atomic energy. Radioactivity ,QC770-798 - Abstract
Abstract The Search for Hidden Particles (SHiP) Collaboration has proposed a general-purpose experimental facility operating in beam-dump mode at the CERN SPS accelerator to search for light, feebly interacting particles. In the baseline configuration, the SHiP experiment incorporates two complementary detectors. The upstream detector is designed for recoil signatures of light dark matter (LDM) scattering and for neutrino physics, in particular with tau neutrinos. It consists of a spectrometer magnet housing a layered detector system with high-density LDM/neutrino target plates, emulsion-film technology and electronic high-precision tracking. The total detector target mass amounts to about eight tonnes. The downstream detector system aims at measuring visible decays of feebly interacting particles to both fully reconstructed final states and to partially reconstructed final states with neutrinos, in a nearly background-free environment. The detector consists of a 50 $$\mathrm { \,m}$$ m long decay volume under vacuum followed by a spectrometer and particle identification system with a rectangular acceptance of 5 m in width and 10 m in height. Using the high-intensity beam of 400 $$\,\mathrm {GeV}$$ GeV protons, the experiment aims at profiting from the $$4\times 10^{19}$$ 4 × 10 19 protons per year that are currently unexploited at the SPS, over a period of 5–10 years. This allows probing dark photons, dark scalars and pseudo-scalars, and heavy neutral leptons with GeV-scale masses in the direct searches at sensitivities that largely exceed those of existing and projected experiments. The sensitivity to light dark matter through scattering reaches well below the dark matter relic density limits in the range from a few $${\mathrm {\,MeV\!/}c^2}$$ MeV / c 2 up to 100 MeV-scale masses, and it will be possible to study tau neutrino interactions with unprecedented statistics. This paper describes the SHiP experiment baseline setup and the detector systems, together with performance results from prototypes in test beams, as it was prepared for the 2020 Update of the European Strategy for Particle Physics. The expected detector performance from simulation is summarised at the end.
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- 2022
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- View/download PDF
42. The active muon shield in the SHiP experiment
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SHiP collaboration, Akmete, A., Alexandrov, A., Anokhina, A., Aoki, S., Atkin, E., Azorskiy, N., Back, J. J., Bagulya, A., Baranov, A., Barker, G. J., Bay, A., Bayliss, V., Bencivenni, G., Berdnikov, A. Y., Berdnikov, Y. A., Bertani, M., Betancourt, C., Bezshyiko, I., Bezshyyko, O., Bick, D., Bieschke, S., Blanco, A., Boehm, J., Bogomilov, M., Bondarenko, K., Bonivento, W. M., Boyarsky, A., Brenner, R., Breton, D., Brundler, R., Bruschi, M., Büscher, V., Buonaura, A., Buontempo, S., Cadeddu, S., Calcaterra, A., Campanelli, M., Chauveau, J., Chepurnov, A., Chernyavsky, M., Choi, K. -Y., Chumakov, A., Ciambrone, P., Dallavalle, G. M., D'Ambrosio, N., D'Appollonio, G., De Lellis, G., De Roeck, A., De Serio, M., Dedenko, L., Di Crescenzo, A., Di Marco, N., Dib, C., Dijkstra, H., Dmitrenko, V., Domenici, D., Donskov, S., Dubreuil, A., Ebert, J., Enik, T., Etenko, A., Fabbri, F., Fabbri, L., Fedin, O., Fedorova, G., Felici, G., Ferro-Luzzi, M., Fini, R. A., Fonte, P., Franco, C., Fukuda, T., Galati, G., Gavrilov, G., Gerlach, S., Golinka-Bezshyyko, L., Golubkov, D., Golutvin, A., Gorbunov, D., Gorbunov, S., Gorkavenko, V., Gornushkin, Y., Gorshenkov, M., Grachev, V., Graverini, E., Grichine, V., Guler, A. M., Guz, Yu., Hagner, C., Hakobyan, H., van Herwijnen, E., Hollnagel, A., Hosseini, B., Hushchyn, M., Iaselli, G., Iuliano, A., Jacobsson, R., Jonker, M., Kadenko, I., Kamiscioglu, C., Kamiscioglu, M., Khabibullin, M., Khaustov, G., Khotyantsev, A., Kim, S. H., Kim, V., Kim, Y. G., Kitagawa, N., Ko, J. -W., Kodama, K., Kolesnikov, A., Kolev, D. I., Kolosov, V., Komatsu, M., Konovalova, N., Korkmaz, M. A., Korol, I., Korol'ko, I., Korzenev, A., Kovalenko, S., Krasilnikova, I., Krivova, K., Kudenko, Y., Kurochka, V., Kuznetsova, E., Lacker, H. M., Lai, A., Lanfranchi, G., Lantwin, O., Lauria, A., Lebbolo, H., Lee, K. Y., Lévy, J. -M., Likacheva, V., Lopes, L., Lyubovitskij, V., Maalmi, J., Magnan, A., Maleev, V., Malinin, A., Mefodev, A., Mermod, P., Mikado, S., Mikhaylov, Yu., Milstead, D. A., Mineev, O., Montanari, A., Montesi, M. C., Morishima, K., Movchan, S., Naganawa, N., Nakamura, M., Nakano, T., Novikov, A., Obinyakov, B., Ogawa, S., Okateva, N., Owen, P. H., Paoloni, A., Park, B. D., Paparella, L., Pastore, A., Patel, M., Pereyma, D., Petrenko, D., Petridis, K., Podgrudkov, D., Poliakov, V., Polukhina, N., Prokudin, M., Prota, A., Rademakers, A., Ratnikov, F., Rawlings, T., Razeti, M., Redi, F., Ricciardi, S., Roganova, T., Rogozhnikov, A., Rokujo, H., Rosa, G., Rovelli, T., Ruchayskiy, O., Ruf, T., Samoylenko, V., Saputi, A., Sato, O., Savchenko, E. S., Schmidt-Parzefall, W., Serra, N., Shakin, A., Shaposhnikov, M., Shatalov, P., Shchedrina, T., Shchutska, L., Shevchenko, V., Shibuya, H., Shustov, A., Silverstein, S. B., Simone, S., Skorokhvatov, M., Smirnov, S., Sohn, J. Y., Sokolenko, A., Starkov, N., Storaci, B., Strolin, P., Takahashi, S., Timiryasov, I., Tioukov, V., Tosi, N., Treille, D., Tsenov, R., Ulin, S., Ustyuzhanin, A., Uteshev, Z., Vankova-Kirilova, G., Vannucci, F., Venkova, P., Vilchinski, S., Villa, M., Vlasik, K., Volkov, A., Voronkov, R., Wanke, R., Woo, J. -K., Wurm, M., Xella, S., Yilmaz, D., Yilmazer, A. U., Yoon, C. S., and Zaytsev, Yu.
- Subjects
Physics - Instrumentation and Detectors ,High Energy Physics - Experiment - Abstract
The SHiP experiment is designed to search for very weakly interacting particles beyond the Standard Model which are produced in a 400 GeV/c proton beam dump at the CERN SPS. An essential task for the experiment is to keep the Standard Model background level to less than 0.1 event after $2\times 10^{20}$ protons on target. In the beam dump, around $10^{11}$ muons will be produced per second. The muon rate in the spectrometer has to be reduced by at least four orders of magnitude to avoid muon-induced combinatorial background. A novel active muon shield is used to magnetically deflect the muons out of the acceptance of the spectrometer. This paper describes the basic principle of such a shield, its optimization and its performance., Comment: 8 pages, 5 figures; added clarifications to the penalty function and emphasized that we care about neutrino interactions in the air
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- 2017
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43. Managing for Security
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Hollnagel, Erik, Masys, Anthony J., Series Editor, Bichler, Gisela, Advisory Editor, Bourlai, Thirimachos, Advisory Editor, Johnson, Chris, Advisory Editor, Karampelas, Panagiotis, Advisory Editor, Leuprecht, Christian, Advisory Editor, Morse, Edward C., Advisory Editor, Skillicorn, David, Advisory Editor, Yamagata, Yoshiki, Advisory Editor, Jacobs, Gabriele, editor, Suojanen, Ilona, editor, Horton, Kate E., editor, and Bayerl, Petra Saskia, editor
- Published
- 2021
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- View/download PDF
44. On the brink of disruption: Applying Resilience Engineering to anticipate system performance under crisis
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Arcuri, Rodrigo, Bellas, Hugo Cesar, Ferreira, Denise de Souza, Bulhões, Bárbara, Vidal, Mario Cesar Rodríguez, Carvalho, Paulo Victor Rodrigues de, Jatobá, Alessandro, and Hollnagel, Erik
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- 2022
- Full Text
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45. A systems analysis of the COVID-19 pandemic response in the United Kingdom – Part 1 – The overall context
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Slater, David, Hollnagel, Erik, MacKinnon, Ralph, Sujan, Mark, Carson-Stevens, Andrew, Ross, Alistair, and Bowie, Paul
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- 2022
- Full Text
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46. Status epilepticus induces chronic silencing of burster and dominance of regular firing neurons during sharp wave-ripples in the mouse subiculum
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Kristina Lippmann, Zin-Juan Klaft, Seda Salar, Jan-Oliver Hollnagel, Manuel Valero, and Anna Maslarova
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Hippocampus ,Subiculum ,Sharp wave-ripples ,Status epilepticus ,Epilepsy ,Burster neurons ,Neurosciences. Biological psychiatry. Neuropsychiatry ,RC321-571 - Abstract
Summary: Sharp wave-ripples (SWRs) are hippocampal oscillations associated with memory consolidation. The subiculum, as the hippocampal output structure, ensures that hippocampal memory representations are transferred correctly to the consolidating neocortical regions. Because patients with temporal lobe epilepsy often develop memory deficits, we hypothesized that epileptic networks may disrupt subicular SWRs. We therefore investigated the impact of experimentally induced status epilepticus (SE) on subicular SWRs and contributing pyramidal neurons using electrophysiological recordings in mouse hippocampal slices. Subicular SWRs expressed hyperexcitable features post-SE, including increased ripple and unit activity. While regular firing neurons normally remain silent during SWRs, selective disinhibition recruited more regular firing neurons for action potential generation during SWRs post-SE. By contrast, burster neurons generated fewer action potential bursts during SWRs post-SE. Furthermore, altered timing of postsynaptic and action potentials suggested distorted neuronal recruitment during SWRs. Distorted subicular SWRs may therefore impair information processing and memory consolidation in epilepsy.
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- 2022
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47. Quo Vadis?
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Hollnagel, Erik, Nemeth, Christopher P., Nemeth, Christopher P., editor, and Hollnagel, Erik, editor
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- 2022
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48. Work-as-Imagined and Work- as-Done
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Hollnagel, Erik, primary and Clay-Williams, Robyn, additional
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- 2022
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49. Modelling complex socio-technical systems
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Hollnagel, Erik, primary and Clay-Williams, Robyn, additional
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- 2022
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50. Germany's Way from Russian Natural Gas to Green Hydrogen: Network Data, Procedures, and Topologies for Feasible Transition Paths to a Green Hydrogen Transport Infrastructure in Germany, GreenHyDE [gri:n'haɪ̯də] –
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Müller‐Kirchenbauer, Joachim, primary, Evers, Maximilian, additional, Hollnagel, Jeremias, additional, Kuzyaka, Berkan, additional, Jiang, Dongrui, additional, Akça, Okan, additional, Mielich, Tim, additional, Kalz, Maike, additional, and Verwiebe, Paul Anton, additional
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- 2024
- Full Text
- View/download PDF
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