26 results on '"Hollingshead, Brett D."'
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2. Demonstration of In Vitro to In Vivo Translation of a TYK2 Inhibitor That Shows Cross Species Potency Differences
3. Data from Inflammatory Signaling and Aryl Hydrocarbon Receptor Mediate Synergistic Induction of Interleukin 6 in MCF-7 Cells
4. Supplementary Figure 1 from Inflammatory Signaling and Aryl Hydrocarbon Receptor Mediate Synergistic Induction of Interleukin 6 in MCF-7 Cells
5. Discovery of High-Affinity Small-Molecule Binders of the Epigenetic Reader YEATS4
6. Development challenges for carcinogenicity risk assessments of topical drugs
7. Discovery of High-Affinity Small-Molecule Binders of the Epigenetic Reader YEATS4.
8. Safety Considerations for Epigenetic Mechanisms as Drug Targets: Are Existing Toxicology Studies Fit for Purpose?
9. Sequence motifs associated with hepatotoxicity of locked nucleic acid—modified antisense oligonucleotides
10. Comparison of Hepatic Transcription Profiles of Locked Ribonucleic Acid Antisense Oligonucleotides: Evidence of Distinct Pathways Contributing to Non-target Mediated Toxicity in Mice
11. Zucker Lean Rats With Hepatic Steatosis Recapitulate Asymptomatic Metabolic Syndrome and Exhibit Greater Sensitivity to Drug-Induced Liver Injury Compared With Standard Nonclinical Sprague-Dawley Rat Model
12. Discovery of Tyrosine Kinase 2 (TYK2) Inhibitor (PF-06826647) for the Treatment of Autoimmune Diseases
13. Aryl-hydrocarbon receptor activation regulates constitutive androstane receptor levels in murine and human liver
14. Dual Inhibition of TYK2 and JAK1 for the Treatment of Autoimmune Diseases: Discovery of ((S)-2,2-Difluorocyclopropyl)((1R,5S)-3-(2-((1-methyl-1H-pyrazol-4-yl)amino)pyrimidin-4-yl)-3,8-diazabicyclo[3.2.1]octan-8-yl)methanone (PF-06700841)
15. Divergent roles of hepatitis B Virus X-associated protein 2 (XAP2) in human versus mouse ah receptor complexes
16. Dual Inhibition of TYK2 and JAK1 for the Treatment of Autoimmune Diseases: Discovery of ((S)‑2,2-Difluoro-cyclo-propyl)-((1R,5S)‑3-(2-((1-methyl‑1H‑pyrazol-4-yl)amino)-pyrimidin-4-yl)-3,8-diaza-bicyclo-[3.2...
17. Comparison of Hepatic Transcription Profiles of Locked Ribonucleic Acid Antisense Oligonucleotides: Evidence of Distinct Pathways Contributing to Non-target Mediated Toxicity in Mice
18. High‐Throughput Gene Silencing and mRNA Expression Analysis in Hepatocyte Sandwich Cultures
19. Distinct Roles for Aryl Hydrocarbon Receptor Nuclear Translocator and Ah Receptor in Estrogen-Mediated Signaling in Human Cancer Cell Lines
20. Estrogen Receptor Expression Is Required for Low-Dose Resveratrol-Mediated Repression of Aryl Hydrocarbon Receptor Activity
21. Inflammatory Signaling and Aryl Hydrocarbon Receptor Mediate Synergistic Induction of Interleukin 6 in MCF-7 Cells
22. The Aryl Hydrocarbon Receptor Complex and the Control of Gene Expression
23. Endogenous Hepatic Expression of the Hepatitis B Virus X-Associated Protein 2 Is Adequate for Maximal Association with Aryl Hydrocarbon Receptor-90-kDa Heat Shock Protein Complexes
24. The Aryl Hydrocarbon (Ah) Receptor Transcriptional Regulator Hepatitis B Virus X-associated Protein 2 Antagonizes p23 Binding to Ah Receptor-Hsp90 Complexes and Is Dispensable for Receptor Function
25. Divergent Roles of Hepatitis B Virus X-Associated Protein 2 (XAP2) in Human versus Mouse Ah Receptor Complexes
26. Dual Inhibition of TYK2 and JAK1 for the Treatment of Autoimmune Diseases: Discovery of (( S)-2,2-Difluorocyclopropyl)((1 R,5 S)-3-(2-((1-methyl-1 H-pyrazol-4-yl)amino)pyrimidin-4-yl)-3,8-diazabicyclo[3.2.1]octan-8-yl)methanone (PF-06700841).
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