411 results on '"Hoehn, Kyle L"'
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2. Design, synthesis, and biological evaluation of imidazo[4,5-b]pyridine mitochondrial uncouplers for the treatment of metabolic dysfunction-associated steatohepatitis (MASH)
3. Unsymmetric hydroxylamine and hydrazine BAM15 derivatives as potent mitochondrial uncouplers
4. Design, synthesis and biological evaluation of glucose metabolism inhibitors as anticancer agents
5. Bile acids mediate fructose-associated liver tumour growth in mice
6. Head-to-head comparison of BAM15, semaglutide, rosiglitazone, NEN, and calorie restriction on metabolic physiology in female db/db mice
7. Targeting negative energy balance with calorie restriction and mitochondrial uncoupling in db/db mice
8. Design, Synthesis, and Biological Evaluation of [1,2,5]Oxadiazolo[3,4‑b]pyridin-7-ol as Mitochondrial Uncouplers for the Treatment of Obesity and Metabolic Dysfunction-Associated Steatohepatitis.
9. Acetyl-CoA-carboxylase 1 (ACC1) plays a critical role in glucagon secretion
10. Increased glucosylceramide production leads to decreased cell energy metabolism and lowered tumor marker expression in non-cancerous liver cells
11. Proteomic pathways to metabolic disease and type 2 diabetes in the pancreatic islet
12. Mitochondrial uncoupler SHC517 reverses obesity in mice without affecting food intake
13. Beneficial effects of MGL‐3196 and BAM15 combination in a mouse model of fatty liver disease.
14. Beneficial effects of simultaneously targeting calorie intake and calorie efficiency in diet-induced obese mice
15. Phenotypic screen for oxygen consumption rate identifies an anti-cancer naphthoquinone that induces mitochondrial oxidative stress
16. Breast cancer growth and proliferation is suppressed by the mitochondrial targeted furazano[3,4-b]pyrazine BAM15
17. CDP-DAG synthase 1 and 2 regulate lipid droplet growth through distinct mechanisms
18. Identification of a novel mitochondrial uncoupler that does not depolarize the plasma membrane
19. Corrigendum to “Design, synthesis and biological evaluation of glucose metabolism inhibitors as anticancer agents” [Bioorg. Chem. 151 (2024) 107665]
20. High dietary fat and sucrose result in an extensive and time-dependent deterioration in health of multiple physiological systems in mice
21. Liver-selective imidazolopyrazine mitochondrial uncoupler SHD865 reverses adiposity and glucose intolerance in mice
22. Dynamic Metabolomics Reveals that Insulin Primes the Adipocyte for Glucose Metabolism
23. Transcriptome landscape of long intergenic non-coding RNAs in endometrial cancer
24. BAM15‐mediated mitochondrial uncoupling protects against obesity and improves glycemic control
25. Eosinophil function in adipose tissue is regulated by Krüppel-like factor 3 (KLF3)
26. UGCG overexpression leads to increased glycolysis and increased oxidative phosphorylation of breast cancer cells
27. Mitochondrial uncoupler BAM15 reverses diet-induced obesity and insulin resistance in mice
28. Beneficial effects of simultaneously targeting calorie intake and calorie efficiency in diet-induced obese mice.
29. Disruption of beta cell acetyl-CoA carboxylase-1 in mice impairs insulin secretion and beta cell mass
30. Proteomic pathways to metabolic disease and type 2 diabetes in the pancreatic islet
31. The emerging role of long non-coding RNAs in endometrial cancer
32. Two functionally distinct pools of eNOS in endothelium are facilitated by myoendothelial junction lipid composition
33. UGCG influences glutamine metabolism of breast cancer cells
34. Targeting negative energy balance with calorie restriction and mitochondrial uncoupling in db/db mice
35. Supplemental Figures S1-8 from Metabolic Vulnerabilities in Endometrial Cancer
36. Data from Metabolic Vulnerabilities in Endometrial Cancer
37. Supplemental Methods from Metabolic Vulnerabilities in Endometrial Cancer
38. Oxadiazolopyridine Derivatives as Efficacious Mitochondrial Uncouplers in the Prevention of Diet-Induced Obesity
39. Investigation of circular RNA transcriptome in obesity-related endometrial cancer
40. Dietary effects on liver tumor burden in mice treated with the hepatocellular carcinogen diethylnitrosamine
41. Erk2 Phosphorylation of Drp1 Promotes Mitochondrial Fission and MAPK-Driven Tumor Growth
42. STEAP4 expression in human islets is associated with differences in body mass index, sex, HbA1c, and inflammation
43. Macrophage acetyl-CoA carboxylase regulates acute inflammation through control of glucose and lipid metabolism
44. Genetic inhibition of hepatic acetyl-CoA carboxylase activity increases liver fat and alters global protein acetylation
45. A Novel MitoTimer Reporter Gene for Mitochondrial Content, Structure, Stress, and Damage in Vivo
46. A selective inhibitor of ceramide synthase 1 reveals a novel role in fat metabolism
47. Conversion of oxadiazolo[3,4-b]pyrazines to imidazo[4,5-b]pyrazines via a tandem reduction-cyclization sequence generates new mitochondrial uncouplers
48. Mitochondrial Uncoupler BAM15 Ameliorates Associated Metabolic PCOS Traits in a Hyperandrogenic PCOS Mouse Model
49. Investigating the Expression and Function of the Glucose Transporter GLUT6 in Obesity
50. C‐Cbl regulates c‐MPL receptor trafficking and its internalization
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