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3. Israel−Palestine Conflict: Risk of Sleep Disorders and Post-Traumatic Stress Disorders

Author

Pandi‑Perumal, Seithikurippu R., Gulia, Kamalesh K., Mallick, Hruda Nanda, Shrivastava, Deepak, Mahalaksmi, Arehally Marappa, Chidambaram, Saravana Babu, Kumar, Ramasamy Rajesh, Saravanan, Konda Mani, Ramasubramanian, Chellamuthu, Sivasubramaniam, Sudhakar, Madoro, Derebe, Narasimhan, Meera, Agudelo, Hernán Andrés Marín, Corlateanu, Alexandru, Meira e Cruz, Miguel, Grønli, Janne, van de Put, Willem A. C. M., Hobfoll, Stevan E., van der Velden, Koos, Bjorvatn, Bjørn, Braakman, Mario H., Partinen, Markku, Maercker, Andreas, de Jong, Joop T. V. M., and Berk, Michael

Published
2023
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4. Comparison of Patient Health Questionnaire-9, Edinburgh Postnatal Depression Scale and Hospital Anxiety and Depression – Depression subscale scores by administration mode: An individual participant data differential item functioning meta-analysis

Author

Azar, Marleine, Bhandari, Parash Mani, Chiovitti, Matthew J., He, Chen, Imran, Mahrukh, Krishnan, Ankur, Negeri, Zelalem, Neupane, Dipika, Riehm, Kira E., Yan, Xin Wei, Kloda, Lorie A., Henry, Melissa, Ismail, Zahinoor, Loiselle, Carmen G., Mitchell, Nicholas D., Al-Adawi, Samir, Alvarado, Rubén, Amtmann, Dagmar, Arroll, Bruce, Ayalon, Liat, Baradaran, Hamid R., Barnes, Jacqueline, Beck, Kevin R., Beck, Cheryl Tatano, Bernstein, Charles N., Bindt, Carola, Bombardier, Charles H., Boye, Birgitte, Büel-Drabe, Natalie, Buji, Ryna Imma, Bunevicius, Adomas, Butterworth, Peter, Can, Ceyhun, Carter, Gregory, Chagas, Marcos H., Chan, Juliana C.N., Chan, Lai Fong, Chen, Chih-Ken, Chibanda, Dixon, Chorwe-Sungani, Genesis, Clover, Kerrie, Conroy, Ronán M., Conway, Aaron, Conwell, Yeates, Correa, Humberto, Couto, Thiago Castro e, Cukor, Daniel, Daray, Federico M., de Man-van Ginkel, Janneke M., De Souza, Jennifer, Downing, Marina G., Eapen, Valsamma, Fann, Jesse R., Favez, Nicolas, Felice, Ethel, Fellmeth, Gracia, Ferentinos, Panagiotis P., Fernandes, Michelle, Field, Sally, Figueiredo, Barbara, Fischer, Felix H., Fisher, Jane R.W., Flint, Alastair J., Fujimori, Maiko, Fung, Daniel S.S., Gallagher, Pamela, Gandy, Milena, Gelaye, Bizu, Gholizadeh, Leila, Gibson, Lorna J., Goodyear-Smith, Felicity, Grassi, Luigi, Green, Eric P., Greeno, Catherine G., Hall, Brian J., Hantsoo, Liisa, Haroz, Emily E., Härter, Martin, Hegerl, Ulrich, Helle, Nadine, Hernando, Asuncion, Hides, Leanne, Hobfoll, Stevan E., Honikman, Simone, Howard, Louise M., Hyphantis, Thomas, Iglesias-González, Maria, Inagaki, Masatoshi, Jenewein, Josef, Jeon, Hong Jin, Jetté, Nathalie, Julião, Miguel, Kettunen, Pirjo A., Khamseh, Mohammad E., Kiely, Kim M., Kim, Sung-Wan, Kjærgaard, Marie, Kohlhoff, Jane, Kohrt, Brandon A., König, Hans-Helmut, Kozinszky, Zoltán, Kwan, Yunxin, Lamers, Femke, Lara, María Asunción, Leonardou, Angeliki A., Levin-Aspenson, Holly F., Liu, Shen-Ing, Löbner, Margrit, Loosman, Wim L., Lotrakul, Manote, Loureiro, Sonia R., Love, Anthony W., Löwe, Bernd, Luitel, Nagendra P., Lund, Crick, Maes, Michael, Malt, Ulrik F., Marrie, Ruth Ann, Marsh, Laura, Martínez, Pablo, Marx, Brian P., Matsuoka, Yutaka, McGuire, Anthony, Mehnert, Anja, Michopoulos, Ioannis, Sidik, Sherina Mohd, Müller-Nordhorn, Jacqueline, Muramatsu, Kumiko, Radoš, Sandra Nakić, Navarrete, Laura, Nelson, Christian J., Ng, Chong Guan, Nishi, Daisuke, O'Donnell, Meaghan L., O'Rourke, Suzanne J., Osório, Flávia L., Pabst, Alexander, Pasco, Julie A., Pawlby, Susan J., Peceliuniene, Jurate, Pence, Brian W., Persoons, Philippe, Petersen, Inge, Picardi, Angelo, Ponsford, Jennie L., Pugh, Stephanie L., Pulido, Federico, Quinn, Terence J., Quispel, Chantal, Rathod, Sujit D., Reme, Silje E., Reuter, Katrin, Riedel-Heller, Steffi G., Rooney, Alasdair G., Santos, Iná S., Saracino, Rebecca M., Schellekens, Melanie P.J., Schwarzbold, Marcelo L., Cankorur, Vesile Senturk, Shaaban, Juwita, Sharp, Deborah J., Sharpe, Louise, Shinn, Eileen H., Sidebottom, Abbey, Simard, Sébastien, Singer, Susanne, Skalkidou, Alkistis, Smith-Nielsen, Johanne, Spangenberg, Lena, Stafford, Lesley, Stein, Alan, Stewart, Robert C., Strobel, Natalie A., Su, Kuan-Pin, Sultan, Serge, Sundström-Poromaa, Inger, Sung, Sharon C., Suzuki, Keiko, Tadinac, Meri, Tan, Pei Lin Lynnette, Tandon, S. Darius, Taylor-Rowan, Martin, Teixeira, Antonio L., Tendais, Iva, Tiringer, Istvan, Töreki, Annamária, Tran, Thach D., Trevillion, Kylee, Tschorn, Mira, Turner, Alyna, Væver, Mette S., van der Feltz-Cornelis, Christina M., van Heyningen, Thandi, Vega-Dienstmaier, Johann M., Wagner, Michael, Wagner, Lynne I., Wang, Liang-Jen, Wang, Jian Li, Watson, David, Weyerer, Siegfried B., White, Jennifer, Whooley, Mary A., Wiese, Birgitt, Williams, Lana J., Winkley, Kirsty, Wynter, Karen, Yamada, Mitsuhiko, Yonkers, Kimberly A., Zeng, Qing Zhi, Zhang, Yuying, Harel, Daphna, Wu, Yin, Levis, Brooke, Fan, Suiqiong, Sun, Ying, Xu, Mingyao, Rice, Danielle B., Boruff, Jill, Markham, Sarah, Ioannidis, John P.A., Takwoingi, Yemisi, Patten, Scott B., Ziegelstein, Roy C., Cuijpers, Pim, Gilbody, Simon, Vigod, Simone, Akena, Dickens, Benedetti, Andrea, and Thombs, Brett D.

Published
2024
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6. Five Essential Elements of Immediate and Mid–Term Mass Trauma Intervention: Empirical Evidence

Author

Hobfoll, Stevan E, Watson, Patricia, Bell, Carl C, Bryant, Richard A, Brymer, Melissa J, Friedman, Matthew J, Friedman, Merle, Gersons, Berthold PR, de Jong, Joop, Layne, Christopher M, Maguen, Shira, Neria, Yuval, Norwood, Ann E, Pynoos, Robert S, Reissman, Dori, Ruzek, Josef I, Shalev, Arieh Y, Solomon, Zahava, Steinberg, Alan M, and Ursano, Robert J

Subjects
Clinical Research, Behavioral and Social Science, Violence Research, Violence Against Women, Peace, Justice and Strong Institutions, Disasters, Humans, Violence, Medical and Health Sciences, Psychology and Cognitive Sciences
Abstract

Given the devastation caused by disasters and mass violence, it is critical that intervention policy be based on the most updated research findings. However, to date, no evidence-based consensus has been reached supporting a clear set of recommendations for intervention during the immediate and the mid-term post mass trauma phases. Because it is unlikely that there will be evidence in the near or mid-term future from clinical trials that cover the diversity of disaster and mass violence circumstances, we assembled a worldwide panel of experts on the study and treatment of those exposed to disaster and mass violence to extrapolate from related fields of research, and to gain consensus on intervention principles. We identified five empirically supported intervention principles that should be used to guide and inform intervention and prevention efforts at the early to mid-term stages. These are promoting: 1) a sense of safety, 2) calming, 3) a sense of self- and community efficacy, 4) connectedness, and 5) hope.

Published
2021

8. Scientists Against War: A Plea to World Leaders for Better Governance

Author

Pandi-Perumal, Seithikurippu R., Kumar, Velayudhan Mohan, Pandian, Namasivayam Ganesh, de Jong, Joop T., Andiappan, Sudalaikannu, Corlateanu, Alexandru, Mahalaksmi, Arehally Marappa, Chidambaram, Saravana Babu, Kumar, Ramasamy Rajesh, Ramasubramanian, Chellamuthu, Sivasubramaniam, Sudhakar, Bjørkum, Alvhild Alette, Cutajar, JosAnn, Berk, Michael, Trakht, Ilya, Vrdoljak, Anton, Meira e Cruz, Miguel, Eyre, Harris A., Grønli, Janne, Cardinali, Dainiel P., Maercker, Andreas, van de Put, Willem A. C. M., Guzder, Jaswant, Bjorvatn, Bjørn, Tol, Wietse A., Acuña-Castroviejo, Darío, Meudec, Marie, Morin, Charles M., Partinen, Markku, Barbui, Corrado, Jordans, Mark J. D., Braakman, Mario H., Knaevelsrud, Christine, Pallesen, Ståle, Sijbrandij, Marit, Golombek, Diego Andrés, Espie, Colin A., Cuijpers, Pim, Agudelo, Hernán Andrés Marín, van der Velden, Koos, van der Kolk, Bessel A., Hobfoll, Stevan E., Devillé, Walter L. J. M., Gradisar, Michael, Riemann, Dieter, Axelsson, John, Benítez-King, Gloria, Macy, Robert D., Poberezhets, Vitalii, Hoole, Samuel Ratnajeevan Herbert, Murthy, Rangaswamy Srinivasa, Hegemann, Thomas, Heinz, Andreas, Salvage, Jane, McFarlane, Alexander C., Keukens, Rob, de Silva, Harendra, Oestereich, Cornelia, Wilhelm, Jochen, von Cranach, Michael, Hoffmann, Klaus, Klosinski, Matthias, Bhugra, Dinesh, and Seeman, Mary V.

Published
2022
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9. Do the Morningness-Eveningness questionnaire and Munich ChronoType questionnaire change after morning light treatment?

Author

Burgess, Helen J, Kikyo, Fumitaka, Valdespino-Hayden, Zerbrina, Rizvydeen, Muneer, Kimura, Momoko, Pollack, Mark H, Hobfoll, Stevan E, Rajan, Kumar B, Zalta, Alyson K, and Burns, John W

Subjects
Biological Psychology, Psychology, Neurosciences, Clinical Research, Sleep Research, circadian, human, light, melatonin, sleep, Biological psychology
Abstract

The Morningness-Eveningness Questionnaire (MEQ) and Munich ChronoType Questionnaire (MCTQ) are sometimes used to estimate circadian timing. However, it remains unclear if they can reflect a change in circadian timing after a light treatment. In this study, 31 participants (25-68 years) completed both questionnaires before and after a 13-28 day morning light treatment. The dim light melatonin onset (DLMO), a physiological marker of circadian timing, was also assessed in a subsample of 16 participants. The DLMO phase advanced on average by 47 minutes (p

Published
2018

14. The Accuracy of the Patient Health Questionnaire-9 Algorithm for Screening to Detect Major Depression : An Individual Participant Data Meta-Analysis

Author

He, Chen, Levis, Brooke, Riehm, Kira E., Saadat, Nazanin, Levis, Alexander W., Azar, Marleine, Rice, Danielle B., Krishnan, Ankur, Wu, Yin, Sun, Ying, Imran, Mahrukh, Boruff, Jill, Cuijpers, Pim, Gilbody, Simon, Ioannidis, John P.A., Kloda, Lorie A., McMillan, Dean, Patten, Scott B., Shrier, Ian, Ziegelstein, Roy C., Akena, Dickens H., Arroll, Bruce, Ayalon, Liat, Baradaran, Hamid R., Baron, Murray, Beraldi, Anna, Bombardier, Charles H., Butterworth, Peter, Carter, Gregory, Chagas, Marcos Hortes Nisihara, Chan, Juliana C.N., Cholera, Rushina, Clover, Kerrie, Conwell, Yeates, de Man-van Ginkel, Janneke M., Fann, Jesse R., Fischer, Felix H., Fung, Daniel, Gelaye, Bizu, Goodyear-Smith, Felicity, Greeno, Catherine G., Hall, Brian J., Harrison, Patricia A., Härter, Martin, Hegerl, Ulrich, Hides, Leanne, Hobfoll, Stevan E., Hudson, Marie, Hyphantis, Thomas N., Inagaki, Masatoshi, Ismail, Khalida, Jetté, Nathalie, Khamseh, Mohammad E., Kiely, Kim M., Kwan, Yunxin, Lamers, Femke, Liu, Shen-Ing, Lotrakul, Manote, Loureiro, Sonia R., Löwe, Bernd, Marsh, Laura, McGuire, Anthony, Mohd-Sidik, Sherina, Munhoz, Tiago N., Muramatsu, Kumiko, Osório, Flávia L., Patel, Vikram, Pence, Brian W., Persoons, Philippe, Picardi, Angelo, Reuter, Katrin, Rooney, Alasdair G., da Silva dos Santos, Iná S., Shaaban, Juwita, Sidebottom, Abbey, Simning, Adam, Stafford, Lesley, Sung, Sharon, Tan, Pei Lin Lynnette, Turner, Alyna, van Weert, Henk C.P.M., White, Jennifer, Whooley, Mary A., Winkley, Kirsty, Yamada, Mitsuhiko, Thombs, Brett D., and Benedetti, Andrea

Published
2020

16. Self-reported posttraumatic growth predicts greater subsequent posttraumatic stress amidst war and terrorism

Author

Zalta, Alyson K, Gerhart, James, Hall, Brian J, Rajan, Kumar B, Vechiu, Catalina, Canetti, Daphna, and Hobfoll, Stevan E

Subjects
Clinical and Health Psychology, Psychology, Behavioral and Social Science, 7.1 Individual care needs, Management of diseases and conditions, Peace, Justice and Strong Institutions, Adult, Arabs, Emigration and Immigration, Female, Humans, Interviews as Topic, Israel, Jews, Male, Russia, Self Report, Stress Disorders, Post-Traumatic, Survivors, Terrorism, Warfare, Posttraumatic growth, resource loss, posttraumatic stress, political violence, terrorism, Business and Management, Clinical Psychology
Abstract

Background and objectiveThis study tested three alternative explanations for research indicating a positive, but heterogeneous relationship between self-reported posttraumatic growth (PTG) and posttraumatic stress symptoms (PSS): (a) the third-variable hypothesis that the relationship between PTG and PSS is a spurious one driven by positive relationships with resource loss, (b) the growth over time hypothesis that the relationship between PTG and PSS is initially a positive one, but becomes negative over time, and (c) the moderator hypothesis that resource loss moderates the relationship between PTG and PSS such that PTG is associated with lower levels of PSS as loss increases.Design and methodA nationally representative sample (N = 1622) of Israelis was assessed at three time points during a period of ongoing violence. PTG, resource loss, and the interaction between PTG and loss were examined as lagged predictors of PSS to test the proposed hypotheses.ResultsResults were inconsistent with all three hypotheses, showing that PTG positively predicted subsequent PSS when accounting for main and interactive effects of loss.ConclusionsOur results suggest that self-reported PTG is a meaningful but counterintuitive predictor of poorer mental health following trauma.

Published
2017

28. A Pilot Study of Tailored Cognitive–Behavioral Resilience Training for Trauma Survivors With Subthreshold Distress

Author

Zalta, Alyson K, Tirone, Vanessa, Siedjak, Jennifer, Boley, Randy A, Vechiu, Catalina, Pollack, Mark H, and Hobfoll, Stevan E

Subjects
Clinical and Health Psychology, Psychology, Mind and Body, Anxiety Disorders, Clinical Trials and Supportive Activities, Clinical Research, Behavioral and Social Science, Mental Health, Physical Injury - Accidents and Adverse Effects, Evaluation of treatments and therapeutic interventions, 6.6 Psychological and behavioural, Mental health, Adult, Aged, Cognitive Behavioral Therapy, Feasibility Studies, Female, Humans, Male, Middle Aged, Pilot Projects, Resilience, Psychological, Stress Disorders, Post-Traumatic, Psychiatry, Applied and developmental psychology, Biological psychology, Clinical and health psychology
Abstract

This pilot study evaluated the feasibility, acceptability, and preliminary effectiveness of tailored cognitive-behavioral resilience training (TCBRT) for trauma-exposed individuals with a variety of subsyndromal psychological symptoms. TCBRT is a brief, flexible intervention that allows individuals to select the areas they wish to target using common cognitive-behavioral change principles. There were 14 individuals (78.6% female) who were recruited from a major medical center and enrolled in the 5-session intervention. There were 12 (85.7%) who completed all TCBRT sessions, and 2 (14.3%) who dropped out after 3 sessions. All participants reported that they received benefit from, were engaged in, and were satisfied with the intervention. Of the 12 with postintervention data, 5 of the participants demonstrated reliable increases in resilience and 6 demonstrated reliable decreases in anxiety. These improvements appeared to be maintained at 2-month follow-up; of the 11 participants with follow-up data, 5 demonstrated reliable increases in resilience and 6 demonstrated reliable decreases in anxiety. Our findings suggested that TCRBT was acceptable to trauma-exposed individuals with varying types of subthreshold distress.

Published
2016

29. Harbingers of hope: Scientists and the pursuit of world peace

Author

Pandi-Perumal, Seithikurippu R., primary, van de Put, Willem A. C. M., additional, Maercker, Andreas, additional, Hobfoll, Stevan E., additional, Mohan Kumar, Velayudhan, additional, Barbui, Corrado, additional, Mahalaksmi, Arehally Marappa, additional, Chidambaram, Saravana Babu, additional, Lundmark, Per Olof, additional, Khai, Tual Sawn, additional, Atwoli, Lukoye, additional, Poberezhets, Vitalii, additional, Rajesh Kumar, Ramasamy, additional, Madoro, Derebe, additional, Andrés Marín Agudelo, Hernán, additional, Hoole, Samuel Ratnajeevan Herbert, additional, Teixeira-Santos, Luísa, additional, Pereira, Paulo, additional, Saravanan, Konda Mani, additional, Vrdoljak, Anton, additional, Meira e Cruz, Miguel, additional, Ramasubramanian, Chellamuthu, additional, Tay, Alvin Kuowei, additional, Grønli, Janne, additional, Sijbrandij, Marit, additional, Sivasubramaniam, Sudhakar, additional, Narasimhan, Meera, additional, Mbong, Eta Ngole, additional, Jansson-Fröjmark, Markus, additional, Bjorvatn, Bjørn, additional, de Jong, Joop T. V. M., additional, Braakman, Mario H., additional, Eisenbruch, Maurice, additional, Acuña-Castroviejo, Darío, additional, van der Velden, Koos, additional, Brown, Gregory M., additional, Partinen, Markku, additional, McFarlane, Alexander C., additional, and Berk, Michael, additional

Published
2023
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31. Posttraumatic stress symptoms predict impaired neutrophil recovery in stem cell transplant recipients

Author

Hobfoll, Stevan E, Gerhart, James I, Zalta, Alyson K, Wells, Kurrie, Maciejewski, John, and Fung, Henry

Subjects
Biomedical and Clinical Sciences, Clinical Research, Mental Health, Behavioral and Social Science, Transplantation, Stem Cell Research, Good Health and Well Being, Adult, Aged, Female, Humans, Male, Middle Aged, Neutrophils, Prospective Studies, Stem Cell Transplantation, Stress Disorders, Post-Traumatic, Transplantation, Autologous, Clinical Sciences, Oncology and Carcinogenesis, Psychology, Oncology & Carcinogenesis, Biomedical and clinical sciences
Abstract

ObjectiveDespite the potentially life-saving effects of stem cell transplant (SCT), many transplant patients experience traumatic stress reactions due to mortality threat, interpersonal isolation, financial and occupational loss, and invasive medical procedures. Emerging evidence suggests that trauma-related stress symptoms (TSS) predict significant health complications following SCT. The aim of the current prospective study was to examine TSS in the acute aftermath of SCT as a predictor of neutrophil recovery following SCT, a crucial component of immune defense against infection.MethodsFifty-one autologous SCT recipients were assessed for TSS 7 days after SCT. Patients' absolute neutrophil counts were collected from medical charts for the first 30 days following SCT. Hierarchical linear growth modeling was used to test the hypothesis that TSS at day 7 would be associated with delayed recovery of neutrophil counts from days 9 to 30 post SCT, that is, when neutrophil counts began to recover.ResultsAs hypothesized, TSS measured 7 days after SCT was significantly associated with slower neutrophil recovery even after pre-existing TSS, depression, distress related to physical symptoms, and potential medical confounds were statistically controlled. Exploratory analyses showed that of the TSS symptom clusters, re-experiencing symptoms and hyperarousal symptoms predicted neutrophil recovery, whereas avoidance symptoms did not.ConclusionThough traumatic stress symptoms may be a normative response to SCT, our findings suggest that TSS following SCT may interfere with neutrophil recovery and overall health. These results provide further insight as to potential mechanisms by which traumatic stress translates to poor medical outcomes for SCT patients.

Published
2015

34. Regular drinking may strengthen the beneficial influence of social support on depression: Findings from a representative Israeli sample during a period of war and terrorism

Author

Kane, Jeremy C, Rapaport, Carmit, Zalta, Alyson K, Canetti, Daphna, Hobfoll, Stevan E, and Hall, Brian J

Subjects
Public Health, Health Sciences, Behavioral and Social Science, Alcoholism, Alcohol Use and Health, Depression, Mental Health, Substance Misuse, Cancer, Mental health, Peace, Justice and Strong Institutions, Adult, Alcohol Drinking, Ethnicity, Female, Health Status, Humans, Israel, Male, Middle Aged, Religion, Social Support, Socioeconomic Factors, Stress Disorders, Post-Traumatic, Terrorism, Warfare, PTSD, Social support, Alcohol use, Prolonged conflict, Political violence, Ethnic Groups, Medical and Health Sciences, Psychology and Cognitive Sciences, Substance Abuse, Biochemistry and cell biology, Pharmacology and pharmaceutical sciences, Epidemiology
Abstract

BackgroundSocial support is consistently associated with reduced risk of depression. Few studies have investigated how this relationship may be modified by alcohol use, the effects of which may be particularly relevant in traumatized populations in which rates of alcohol use are known to be high.MethodsIn 2008 a representative sample of 1622 Jewish and Palestinian citizens in Israel were interviewed by phone at two time points during a period of ongoing terrorism and war threat. Two multivariable mixed effects regression models were estimated to measure the longitudinal association of social support from family and friends on depression symptoms. Three-way interaction terms between social support, alcohol use and time were entered into the models to test for effect modification.ResultsFindings indicated that increased family social support was associated with less depression symptomatology (p=

Published
2014

38. Conservation of resources theory and research use in health systems

Author

Alvaro, Celeste, Lyons, Renée F, Warner, Grace, Hobfoll, Stevan E, Martens, Patricia J, Labonté, Ronald, and Brown, Richard E

Abstract

Abstract Background Health systems face challenges in using research evidence to improve policy and practice. These challenges are particularly evident in small and poorly resourced health systems, which are often in locations (in Canada and globally) with poorer health status. Although organizational resources have been acknowledged as important in understanding research use resource theories have not been a focus of knowledge translation (KT) research. What resources, broadly defined, are required for KT and how does their presence or absence influence research use? In this paper, we consider conservation of resources (COR) theory as a theoretical basis for understanding the capacity to use research evidence in health systems. Three components of COR theory are examined in the context of KT. First, resources are required for research uptake. Second, threat of resource loss fosters resistance to research use. Third, resources can be optimized, even in resource-challenged environments, to build capacity for KT. Methods A scan of the KT literature examined organizational resources needed for research use. A multiple case study approach examined the three components of COR theory outlined above. The multiple case study consisted of a document review and key informant interviews with research team members, including government decision-makers and health practitioners through a retrospective analysis of four previously conducted applied health research studies in a resource-challenged region. Results The literature scan identified organizational resources that influence research use. The multiple case study supported these findings, contributed to the development of a taxonomy of organizational resources, and revealed how fears concerning resource loss can affect research use. Some resources were found to compensate for other resource deficits. Resource needs differed at various stages in the research use process. Conclusions COR theory contributes to understanding the role of resources in research use, resistance to research use, and potential strategies to enhance research use. Resources (and a lack of them) may account for the observed disparities in research uptake across health systems. This paper offers a theoretical foundation to guide further examination of the COR-KT ideas and necessary supports for research use in resource-challenged environments.

Published
2010

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