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1. Curriculum mapping of accredited pharmacy programs in the United States

Author

Talasaz, Azita H., Donohoe, Krista L., Van Tassell, Benjamin, Truong, Albert, Shaunak, Allison, Wayne, April, Brenner, Autumn, Cherian, Benjamin, Long, Bradley, Clemons, Brianna, Cason, Caitlyn, Hoang, Catherine Chi, Tran, Christine, Dent, David, Quinn, Erin, Allegra, Anthony Garrett, Price, Graham, Sharp, Haley, Nguyen, Huyen, Gomez, Jason, Hodge, Jennifer, Lai, Jessica, Everett, Jordan, Hunt, Joseph, Zhang, Josh, Zhang, Joshua, Hsu, Jun, Bowles, Katherine, Rowe, Kayla, Loch, Kaylin, Han, Khiem, Reid, Kodi, So, Lisa, Noble, Madison, Puryear, Madison, Dance, Makeisha, Bland, Megan, LaPorte, Michael, Lowe, Nia, DiStefano, Nicholas, Crawford, Priscila, Spence, Rowan, Fleku, Sandra, Henderson, Sarah, Viramgama, Saumya, Lee, Sera, Yang, Sooin, Vickhouse, Stanley, Saunders, Sterling, Roussel, Sydney, Cuffee, Tayana, Huynh, Tiffany, Olajide, Tolulope, and Yousufzai, Yanis

Published
2023
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12. Letting it matter

Author

Hoang, Catherine

Subjects
News, opinion and commentary, Sports and fitness
Abstract

Byline: Catherine Hoang I spent my time at Spec learning and dealing with the multitudes of a single truth: The story is always more complicated than it seems. Most of [...]

Published
2019

13. Thyroid follicular adenomas and carcinomas: molecular profiling provides evidence for a continuous evolution.

Author

UCL - SSS/DDUV - Institut de Duve, UCL - SSS/DDUV/CELL - Biologie cellulaire, UCL - (SLuc) Service d'anatomie pathologique, Dom, Geneviève, Frank, Sandra, Floor, Sebastien, Kehagias, Pashalina, Libert, Frederick, Hoang, Catherine, Andry, Guy, Spinette, Alex, Craciun, Ligia, de Saint Aubin, Nicolas, Tresallet, Christophe, Tissier, Frederique, Savagner, Frederique, Majjaj, Samira, Gutierrez-Roelens, Ilse, Marbaix, Etienne, Dumont, Jacques E, Maenhaut, Carine, UCL - SSS/DDUV - Institut de Duve, UCL - SSS/DDUV/CELL - Biologie cellulaire, UCL - (SLuc) Service d'anatomie pathologique, Dom, Geneviève, Frank, Sandra, Floor, Sebastien, Kehagias, Pashalina, Libert, Frederick, Hoang, Catherine, Andry, Guy, Spinette, Alex, Craciun, Ligia, de Saint Aubin, Nicolas, Tresallet, Christophe, Tissier, Frederique, Savagner, Frederique, Majjaj, Samira, Gutierrez-Roelens, Ilse, Marbaix, Etienne, Dumont, Jacques E, and Maenhaut, Carine

Abstract

Non-autonomous thyroid nodules are common in the general population with a proportion found to be cancerous. A current challenge in the field is to be able to distinguish benign adenoma (FA) from preoperatively malignant thyroid follicular carcinoma (FTC), which are very similar both histologically and genetically. One controversial issue, which is currently not understood, is whether both tumor types represent different molecular entities or rather a biological continuum. To gain a better insight into FA and FTC tumorigenesis, we defined their molecular profiles by mRNA and miRNA microarray. Expression data were analyzed, validated by qRT-PCR and compared with previously published data sets. The majority of deregulated mRNAs were common between FA and FTC and were downregulated, however FTC showed additional deregulated mRNA. Both types of tumors share deregulated pathways, molecular functions and biological processes. The additional deregulations in FTC include the lipid transport process that may be involved in tumor progression. The strongest candidate genes which may be able to discriminate follicular adenomas and carcinomas, CRABP1, FABP4 and HMGA2, were validated in independent samples by qRT-PCR and immunohistochemistry. However, they were not able to adequately classify FA or FTC, supporting the notion of continuous evolving tumors, whereby FA and FTC appear to show quantitative rather than qualitative changes. Conversely, miRNA expression profiles showed few dysregulations in FTC, and even fewer in FA, suggesting that miRNA play a minor, if any, role in tumor progression.

Published
2018

14. Thyroid follicular adenomas and carcinomas: molecular profiling provides evidence for a continuous evolution.

Author

Dom, Geneviève, Frank, Sandra, Floor, Sebastien, Kehagias, Pashalina, Libert, Frédérick, Hoang, Catherine, Andry, Guy, Spinette, Alex, Ruscas-Craciun, Ligia Ioana, de Saint Aubin, Nicolas, Tresallet, Christophe, Tissier, Frederique, Savagner, Frédérique, Majjaj, Samira, Gutierrez-Roelens, Ilse, Marbaix, Etienne, Dumont, Jacques Emile, Maenhaut, Carine, Dom, Geneviève, Frank, Sandra, Floor, Sebastien, Kehagias, Pashalina, Libert, Frédérick, Hoang, Catherine, Andry, Guy, Spinette, Alex, Ruscas-Craciun, Ligia Ioana, de Saint Aubin, Nicolas, Tresallet, Christophe, Tissier, Frederique, Savagner, Frédérique, Majjaj, Samira, Gutierrez-Roelens, Ilse, Marbaix, Etienne, Dumont, Jacques Emile, and Maenhaut, Carine

Abstract

Non-autonomous thyroid nodules are common in the general population with a proportion found to be cancerous. A current challenge in the field is to be able to distinguish benign adenoma (FA) from preoperatively malignant thyroid follicular carcinoma (FTC), which are very similar both histologically and genetically. One controversial issue, which is currently not understood, is whether both tumor types represent different molecular entities or rather a biological continuum. To gain a better insight into FA and FTC tumorigenesis, we defined their molecular profiles by mRNA and miRNA microarray. Expression data were analyzed, validated by qRT-PCR and compared with previously published data sets. The majority of deregulated mRNAs were common between FA and FTC and were downregulated, however FTC showed additional deregulated mRNA. Both types of tumors share deregulated pathways, molecular functions and biological processes. The additional deregulations in FTC include the lipid transport process that may be involved in tumor progression. The strongest candidate genes which may be able to discriminate follicular adenomas and carcinomas, CRABP1, FABP4 and HMGA2, were validated in independent samples by qRT-PCR and immunohistochemistry. However, they were not able to adequately classify FA or FTC, supporting the notion of continuous evolving tumors, whereby FA and FTC appear to show quantitative rather than qualitative changes. Conversely, miRNA expression profiles showed few dysregulations in FTC, and even fewer in FA, suggesting that miRNA play a minor, if any, role in tumor progression., SCOPUS: ar.j, info:eu-repo/semantics/published

Published
2018

15. The diagnostic value of fine-needle aspiration biopsy under ultrasonography in nonfunctional thyroid nodules: a prospective study comparing cytologic and histologic findings

Author

Cochand-Priollet, Beatrix, Guillausseau, Pierre-Jean, Chagnon, Sophie, Hoang, Catherine, Guillausseau-Scholer, Claudine, Chanson, Philippe, Dahan, Henri, Warnet, Andre, Tran Ba Huy, Patrice, and Valleur, Patrice

Subjects
Thyroid gland -- Abnormalities, Biopsy, Needle, Health, Health care industry
Abstract

Fine-needle aspiration biopsy (FNAB) of thyroid nodules has been proposed as a preoperative screening method to reduce the number of patients with benign nodules referred for surgery. Only a few previously published studies have compared cytologic results with a systematic surgical control; furthermore, the role of ultrasound guidance for FNAB in obtaining representative material has been poorly evaluated. The authors tried to assess the diagnostic value of FNAB performed under ultrasonography in a series of patients with a cold nodule and a systematic surgical control. This prospective study included 132 consecutive patients, 19 men and 113 women, aged from 18 to 82 years. The rate of carcinomas was 13.8%. A very high rate of adequate material was obtained (96.2%). Sensitivity, specificity, and global accuracy were 95%, 87.7%, and 89%, respectively. These results, which are equivalent to those previously published but associated with a low level of insufficient material, emphasize the diagnostic value of thyroid FNAB.

Published
1994

16. Thyroid follicular adenomas and carcinomas: molecular profiling provides evidence for a continuous evolution

Author

Dom, Geneviève, primary, Frank, Sandra, additional, Floor, Sebastien, additional, Kehagias, Pashalina, additional, Libert, Frederick, additional, Hoang, Catherine, additional, Andry, Guy, additional, Spinette, Alex, additional, Craciun, Ligia, additional, de Saint Aubin, Nicolas, additional, Tresallet, Christophe, additional, Tissier, Frederique, additional, Savagner, Frederique, additional, Majjaj, Samira, additional, Gutierrez-Roelens, Ilse, additional, Marbaix, Etienne, additional, Dumont, Jacques E., additional, and Maenhaut, Carine, additional

Published
2017
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17. Thyroid follicular adenomas and carcinomas: molecular profiling provides evidence for a continuous evolution.

Author

SECOND SYMPOSIUM OF THE ULB - CANCER RESEARCH CENTRE (2: Brussels), Dom, Geneviève, Frank, Sandra, Floor, Sebastien, Kehagias, Pashalina, Libert, Frédérick, Hoang, Catherine, Andry, Guy, Spinette, Alex, Ruscas-Craciun, Ligia Ioana, de Saint Aubin, Nicolas, Trésallet, Christophe, Tissier, Frederique, Savagner, Frédérique, Majjaj, Samira, Guttierez, R., Marbaix, Etienne, Dumont, Jacques Emile, Maenhaut, Carine, SECOND SYMPOSIUM OF THE ULB - CANCER RESEARCH CENTRE (2: Brussels), Dom, Geneviève, Frank, Sandra, Floor, Sebastien, Kehagias, Pashalina, Libert, Frédérick, Hoang, Catherine, Andry, Guy, Spinette, Alex, Ruscas-Craciun, Ligia Ioana, de Saint Aubin, Nicolas, Trésallet, Christophe, Tissier, Frederique, Savagner, Frédérique, Majjaj, Samira, Guttierez, R., Marbaix, Etienne, Dumont, Jacques Emile, and Maenhaut, Carine

Abstract

info:eu-repo/semantics/nonPublished

Published
2017

18. microRNA expression in autonomous thyroid adenomas: Correlation with mRNA regulation.

Author

Floor, Sebastien, Trésallet, Christophe, Hebrant, Aline, Desbuleux, Alice, Libert, Frédérick, Hoang, Catherine, Cappello, Matteo, Andry, Guy, van Staveren, Wilma C G, Maenhaut, Carine, Floor, Sebastien, Trésallet, Christophe, Hebrant, Aline, Desbuleux, Alice, Libert, Frédérick, Hoang, Catherine, Cappello, Matteo, Andry, Guy, van Staveren, Wilma C G, and Maenhaut, Carine

Abstract

The objective of the study was to identify the deregulated miRNA in autonomous adenoma and to correlate the data with mRNA regulation. Seven autonomous adenoma with adjacent healthy thyroid tissues were investigated. Twelve miRNAs were downregulated and one was upregulated in the tumors. Combining bioinformatic mRNA target prediction and microarray data on mRNA regulations allowed to identify mRNA targets of our deregulated miRNAs. A large enrichment in mRNA encoding proteins involved in extracellular matrix organization and different phosphodiesterases were identified among these putative targets. The direct interaction between miR-101-3p and miR-144-3p and PDE4D mRNA was experimentally validated. The global miRNA profiles were not greatly modified, confirming the definition of these tumors as minimal deviation tumors. These results support a role for miRNA in the regulation of extracellular matrix proteins and tissue remodeling occurring during tumor development, and in the important negative feedback of the cAMP pathway, which limits the consequences of its constitutive activation in these tumors., SCOPUS: ar.j, info:eu-repo/semantics/published

Published
2015

24. Adrenocortical Tumors

Author

Tissier, Frédérique, primary, Aubert, Sébastien, additional, Leteurtre, Emmanuelle, additional, Al Ghuzlan, Abir, additional, Patey, Martine, additional, Decaussin, Myriam, additional, Doucet, Laurent, additional, Gobet, Françoise, additional, Hoang, Catherine, additional, Mazerolles, Catherine, additional, Monges, Geneviève, additional, Renaudin, Karine, additional, Sturm, Nathalie, additional, Trouette, Hélène, additional, Vacher-Lavenu, Marie-Cécile, additional, Viallon, Vivian, additional, Baudin, Eric, additional, Bertagna, Xavier, additional, Coste, Joël, additional, and Libe, Rossella, additional

Published
2012
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28. Serotonin-producing pancreatic endocrine tumour. Histological, ultrastructural and immunohistochemical study of a case

Author

Kanavaros, Panagiotis, Hoang, Catherine, Le Bodic, Marie Francoise, Polivka, Marc, and Hautefeuille, Pierre

Subjects
Serotonin, Microscopy, Electron, Serotonin/*biosynthesis, 6 - Ciencias aplicadas::61 - Medicina [CDU], Cytoplasmic Granules/ultrastructure, Humans, Adenoma, Islet Cell/metabolism/*pathology/ultrastructure, Female, Pancreatic Neoplasms/metabolism/*pathology/ultrastructure, Middle Aged, Immunohistochemistry
Abstract

Serotonin-producing pancreatic endocrine tumours are rare neoplasms which in most cases exhibit malignant biological behaviour. These tumours, in the majority of the well-documented cases, are composed of argyrophil- and argentaffin-positive cells which contain large pleomorphic neurosecretory granules. In contrast, argyrophilic non-argentaffin pancreatic endocrine tumours with tumour cells containing round neurosecretory granules are exceptional. In this study we describe such a tumour not associated with clinical evidence of carcinoid syndrome in a 60-year-old woman. Histological examination revealed tumour extension in pancreatic lymphatic vessels and veins but no evidence of locoregional or distant metastases. Ten months after surgery the patient showed no recurrence of the disease. Immunohistochernistry revealed cytoplasmic serotonin production in the tumour cells which were negative for anti-gastrin, insulin, glucagon, somatostatin, pancreatic polypeptide (PP), vasoactive intestinal peptide (VIP) and ACTH. This study emphasizes the usefulness of combined ultrastructural and immunohistochemical investigations in order to identify and characterize the rare pancreatic endocrine tumours with serotonin production.

Published
1990

32. Effects of ursodeoxycholic acid (ursodiol) treatment on chronic viral hepatitis in heart transplant patients: results of a prospective, double-blind, placebo-randomized study

Author

Cadranel, Jean-François, primary, Di Martino, Vincent, additional, Dorent, Richard, additional, Bernard, Brigitte, additional, Hoang, Catherine, additional, Myara, Anne, additional, Pauwels, Arnaud, additional, Ghoussoub, Jean-Jacques, additional, Perrin, Michèle, additional, Grippon, Patrick, additional, Thabut, Dominique, additional, Trivin, François, additional, Huraux, Jean-Marie, additional, Gandjbakhch, Iradj, additional, Opolon, Pierre, additional, and Lunel, Françoise, additional

Published
2003
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33. Selection of Patients with Solitary Thyroid Nodules for Operation

Author

Leenhardt, Laurence, primary, Menegaux, Fabrice, additional, Franc, Brigitte, additional, Delbot, Thierry, additional, Mansour, Georges, additional, Hoang, Catherine, additional, Guillausseau, Claudine, additional, Aurengo, Helyett, additional, Guillouzic, Danièle Le, additional, Turpin, Gérard, additional, Aurengo, André, additional, Chigot, Jean Paul, additional, and Hejblum, Gilles, additional

Published
2002
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34. LIVER DYSFUNCTION IN ALLOGENEIC BONE MARROW TRANSPLANTATION RECIPIENTS

Author

Azar, Nabih, primary, Valla, Dominique, additional, Abdel-Samad, Issam, additional, Hoang, Catherine, additional, Fretz, Catherine, additional, Sutton, Laurent, additional, Fournel, Jean-Jacques, additional, Charpentier, Yves Le, additional, Binet, Jacques-Louis, additional, and Leblond, Véronique, additional

Published
1996
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35. The reply

Author

Cochand-Priollet, Béatrix, primary, Guillausseau, Pierre-Jean, additional, Chagnon, Sophie, additional, Hoang, Catherine, additional, Guillausseau-Scholer, Claudine, additional, Chanson, Philippe, additional, Dahan, Henri, additional, Warnet, André, additional, Huy, Patrice Tran Ba, additional, and Valleur, Patrice, additional

Published
1995
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37. Rectal Malacoplakia in Renal Transplantation

Author

Bellin, Marie-France, primary, Darchen, Marie-Annick, additional, Hoang, Catherine, additional, Bitker, Marc-Olivier, additional, Ourhama, Saida, additional, Attal, Martine, additional, and Grellet, Jacques, additional

Published
1994
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39. AIDS-related cholangiopathy

Author

Benhamou, Yves, primary, Caumes, Eric, additional, Gerosa, Yves, additional, Cadranel, Jean François, additional, Dohin, Elisabeth, additional, Katlama, Christine, additional, Amouyal, Paul, additional, Canard, Jean Marc, additional, Azar, Nabih, additional, Hoang, Catherine, additional, Le Charpentier, Yves, additional, Gentilini, Marc, additional, Opolon, Pierre, additional, and Valla, Dominique, additional

Published
1993
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41. Quantitation of plasma cells in duodenal biopsies from patients with acquired immunodeficiency syndrome. Comparison with serum and fecal immunoglobulins concentrations

Author

Opolon Pierre, Le Charpentier Yves, Hoang Catherine, Schovaert Damien, Benhamou Yves, Gobert Jean-Gérard, Nasr Georges, Kapel Nathalie, and Rapheal Martine

Subjects
biology, Acquired immunodeficiency syndrome (AIDS), Immunology, biology.protein, medicine, Cell Biology, General Medicine, Antibody, medicine.disease, Feces
Published
1992

42. From Travelers' Diarrhea to Abdominal Surgery.

Author

Caumes, Eric, Bricaire, François, Ménégaux, Fabrice, Duhem, Cecile, Chigot, Jean-Paul, and Hoang, Catherine

Subjects
INTESTINAL diseases, DIARRHEA, TRAVEL hygiene, CLINICAL medicine
Abstract

This article presents cases of severe intestinal disease that started as severe travelers' diarrhea (TD) and ended with abdominal surgery. TD is a common medical problem among visitors to tropical regions, and is usually a self-limited disease. Three factors may have contributed to severe outcome: undiagnosed amebic or Clostridium difficile-associated colitis, lack of adequate medical care and delay in diagnosis. The patients initially complained of severe TD. At least two received loperamide. None received appropriate initial antimicrobial chemotherapy. The TD progressed to febrile ileus in two patients and peritonitis in one patient. No microbial pathogens were isolated from stools or blood. Serodiagnosis of amebiasis was negative. Laparatomy was performed several days after the onset of TD. Amebic colitis was suspected in two cases, in association with Clostridium difficile colitis in one case. Travelers must be better informed about what to do if they suffer from diarrhea. Indeed, they need to be advised that, if diarrhea occurs, they should take their temperature and examine their stools visually for blood, and should use loperamide and antimicrobial agents only as indicated.

Published
2004

44. Severe Diarrhea in a Patient With AIDS

Author

Guerin, Jean-Michel, Hoang, Catherine, Galian, Annie, Lavergne, Anne, Lebiez, Eric, and Bitoun, Alain

Abstract

To the Editor.—The recent publication by Green et al1 of two cases of acquired immunodeficiency syndrome (AIDS), in which the presenting features mimicked Crohn's disease, prompts us to report a similar case.Report of a Case.—A 46-year-old homosexual Frenchman, with multiple sexual partners, was admitted to the hospital because of diarrhea and fever. Stool examination revealed Gardia lamblia, Endolimax nana, and Pseudolimax butchilii, but no Salmonella, Shigella, and Campylobacter. Colonoscopy showed disseminated superficial linear or irregular ulcerations predominantly in the left colon. Pathological study of distal ileal and colonic biopsy specimens showed a mild inflammatory infiltration of the lamina propria by plasma cells, polymorphs and macrophages, rare signs of cryptitis, and colonic erosions. Neither ileal villous atrophy nor pathogens were observed. (A basophil body at the basal area of an enterocyte could have been a Coccidia, of Isospora belli type, but this finding was not confirmed by

Published
1986
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45. An Unusual Umbilical Mass.

Author

Adem, Camilo, Schneider, Marc, and Hoang, Catherine

Subjects
*TUMORS, *CYSTS (Pathology), *ONCOLOGY, *NAVEL, *SYMPTOMS
Abstract

Provides information on a case study of a 34-year-old black man with adenomatoid tumor of the umbilicus. Symptoms; Basis for the establishment of the mesothelial origin of adenomatoid tumors from different sites; Characterization of the case of adenomatoid tumor.

Published
2003
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46. 2011 CONFERENCE CHOIR SCHOLARSHIP REFLECTIONS.

Author

Beascochea, Carlos, Bustos, Victoria, Camacho, Claudia, Cross, Averi Cheyenne, D'Souza, Kevin, Grip, Jillian, Hoang, Catherine, Lowry, Brie, McKenzie, Dora, and White, Joiya

Subjects
*CONFERENCES & conventions, *CHOIRS (Musical groups)
Abstract

The article presents reflections from the participants of the 2011 Conference Choir Scholarship sponsored by the Organization of American Kodály Educators (OAKE) in the U.S. Carlos Beascochea acknowledge the conference for his learning experience. Victoria Bustos felt nervous when performing in front of a large audience. Averi Cheyenne Cross felt blessed in taking part of the OAKE conference.

Published
2011

47. Adrenocortical tumors: improving the practice of the Weiss system through virtual microscopy: a National Program of the French Network INCa-COMETE.

Author

Tissier F, Aubert S, Leteurtre E, Al Ghuzlan A, Patey M, Decaussin M, Doucet L, Gobet F, Hoang C, Mazerolles C, Monges G, Renaudin K, Sturm N, Trouette H, Vacher-Lavenu MC, Viallon V, Baudin E, Bertagna X, Coste J, and Libe R

Subjects
Adrenal Cortex Neoplasms epidemiology, France, Humans, Observer Variation, Reproducibility of Results, Adrenal Cortex Neoplasms diagnosis, Microscopy methods, Pathology, Clinical methods, Pathology, Clinical standards, User-Computer Interface
Abstract

The Weiss score is the reference method to distinguish between a benign and a malignant adrenocortical tumor (ACT). A program was initiated to improve the reproducibility of the pathologic diagnosis of ACTs in France through the National INCa-COMETE Network. Twelve pathologists from all Reference Centers of the Network analyzed 50 selected ACTs using a web-based virtual microscopy approach in a blind design, allowing to determine the intraobserver and interobserver reproducibilities of the Weiss system. All ACTs were read twice in random order before and after a coaching meeting organized to harmonize and improve analyses and create an online tutorial. The validity of the virtual approach was first established by comparing the 2 consensuses (virtual and microscopic) obtained for each tumor by 3 pathologists who performed the 2 approaches in a blinded manner. For the "dichotomized Weiss score" (separating malignant ≥3 from benign ≤2 tumors) interobserver reproducibility was "substantial" at the first "virtual" reading (κ = 0.70) and increased at the second "virtual" reading (κ = 0.75). In parallel, 7 of the 9 items of the Weiss system showed improvement. The diagnostic accuracy of the observers as a group, using the modal group score approach, showed an improved sensitivity from 86% to 95% for the diagnosis of malignant ACTs. We show the validity of the virtual microscopy approach and that the program improved the practice of the Weiss system reading and therefore the diagnosis of ACT. This tool can now be extended for other research and/or routine purposes in this rare cancer.

Published
2012
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48. [An unusual mutinodular goiter].

Author

Hoang C, Le Naour G, Ménégaux F, and Capron F

Subjects
Deglutition Disorders etiology, Female, Goiter, Nodular parasitology, Humans, Middle Aged, Neoplasm Metastasis, Ultrasonography, Voice Disorders etiology, Goiter, Nodular diagnostic imaging, Hemangiosarcoma pathology, Thyroid Neoplasms pathology
Published
2009
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49. [Rare incidentalomas: diagnostic procedure].

Author

Hoang C

Subjects
Adrenal Gland Diseases diagnosis, Adrenal Gland Diseases pathology, Adrenal Gland Neoplasms diagnostic imaging, Adrenal Gland Neoplasms epidemiology, Adrenal Gland Neoplasms pathology, Adrenal Gland Neoplasms secondary, Diagnosis, Differential, Diagnostic Imaging, Female, Histoplasmosis diagnosis, Humans, Incidental Findings, Male, Prevalence, Radiography, Tuberculosis, Endocrine diagnosis, Ultrasonography, Adrenal Gland Neoplasms diagnosis
Published
2008
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50. [An unusual cause of jejunal intussusception: heterotopic and hyperplastic Brunner's gland pseudo-tumor].

Author

Just PA, Hoang C, Cadi M, Menegaux F, and Capron F

Subjects
Abdominal Pain etiology, Adult, Female, Humans, Intussusception pathology, Jejunal Diseases pathology, Brunner Glands, Choristoma, Intussusception etiology, Intussusception surgery, Jejunal Diseases etiology, Jejunal Diseases surgery
Abstract

We report the first case of small-bowel intussusception caused by a tumour-like Brunner's gland hyperplasia in a 26 year old woman. The patient presented with intense abdominal pain. Abdominal and pelvic contrast enhanced CT-scan suggested small bowel intussusception involving the first jejunal loop. A 15 cm long polypoid mass was found in the jejunumectomy specimen (2nd and 3rd loops). Histological examination revealed Brunner's gland hyperplasia in the jejunal mucosa and submucosa. Considering the jejunal location of the lesion, it must be considered malformative and heterotopic Brunner's gland hyperplasia.

Published
2005
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