Oxide semiconductor electronics may enable new applications including large-area, flexible, integrated systems. ZnO thin film transistors have been reported with field-effect mobility > 100 cm2/V·s, on-current density > 700 mA/mm, and microwave operation (f T > 2 GHz, f max > 7 GHz) for ZnO deposited by pulsed laser deposition at 400°C.[1] Other oxide semiconductors, including amorphous and crystalline mixtures of I 2 O 3 , Ga 2 O 3 , ZnO, have also been widely studied, and high mobility (> 30 cm2/V·s) thin film transistors and circuits with propagation delays d = dI DS /dV DS ) observed in a range of oxide thin film transistors. In particular we find that self-heating is a significant limiting factor for the performance of oxide devices and circuits on low-cost, low-thermal conductivity substrates such as glass and plastic.