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847 results on '"Hjortdal, Vibeke E."'

13. Early changes in cerebral metabolism after perinatal hypoxia-ischemia: a study in normothermic and hypothermic piglets

Author

Andelius, Ted C. K., primary, Bøgh, Nikolaj, additional, Pedersen, Mette V., additional, Omann, Camilla, additional, Andersen, Mads, additional, Andersen, Hannah B., additional, Hjortdal, Vibeke E., additional, Pedersen, Michael, additional, Rasmussen, Martin B., additional, Kyng, Kasper J., additional, and Henriksen, Tine B., additional

Published
2023
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16. The effect of early follow-up after open cardiac surgery in a student clinic.

Author

Ilkjær, Christine, Hoffmann, Torben, Heiberg, Johan, Hansen, Laura Sommer, and Hjortdal, Vibeke E.

Abstract

Objectives. Readmission rates following open cardiac surgery are high, affecting patients and the cost of care. This study aimed to investigate the effect of early additional follow-up after open cardiac surgery when 5th-year medical students conducted follow-ups under the supervision of physicians. The primary endpoint was unplanned cardiac-related readmissions within one year. The secondary outcomes were the detection of impending complications and health-related quality of life (HRQOL). Methods. Patients undergoing open cardiac surgery were prospectively included. For intervention, additional follow-up visits, including point-of-care ultrasound, were conducted by supervised 5th-year medical students on postoperative days 3, 14 and 25. Unplanned cardiac-related readmissions, including emergency department visits, were registered within the first year of surgery. Danish National Health Survey 2010 questionnaire was used for HRQOL. In standard follow-up, all patients were seen 4-6 weeks postoperative. Results. For data analysis, 100 of 124 patients in the intervention group and 319 of 335 patients in the control group were included. The 1-year unplanned readmission rates did not differ; 32% and 30% in the intervention and control groups, respectively (p = 0.71). After discharge, 1% of patients underwent pericardiocentesis. The additional follow-up initiated scheduled drainage, contrary to more unscheduled/acute drainages in the control group. Pleurocentesis was more common in the intervention group (17% (n = 17) vs 8% (n = 25), p = 0.01) and performed earlier. There was no difference between groups on HRQOL. Conclusion. Supervised student-led follow-up of newly cardiac-operated patients did not alter readmission rates or HRQOL but may detect complications earlier and initiate non-emergent treatment of complications. [ABSTRACT FROM AUTHOR]

Published
2023
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17. A novel algorithm for classification of interatrial communications within the oval fossa in the newborn.

Author

Dannesbo, Sofie, Blixenkrone-Moeller, Elisabeth, Pihl, Christian A., Sillesen, Anne-Sophie, Voegg, Ruth O., Davidsen, Agnes S., Lind, Louise E., Jeppesen, Dorthe L., Kruse, Charlotte, Noerager, Betina, Dodd, James K., Jorgensen, Finn S., Raja, Anna A., Colan, Steven D., Mertens, Luc, Hjortdal, Vibeke E., Vejlstrup, Niels, Anderson, Robert H., Bundgaard, Henning, and Iversen, Kasper

Published
2023
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18. Lymphatic Abnormalities on Magnetic Resonance Imaging in Single-Ventricle Congenital Heart Defects Before Glenn Operation

Author

Kristensen, Rasmus, Kelly, Benjamin, Kim, Emily, Dori, Yoav, and Hjortdal, Vibeke E

Subjects
Lymphatic Abnormalities/diagnostic imaging, Treatment Outcome, Heart Defects, Congenital/diagnostic imaging, Humans, Infant, Heart Ventricles/diagnostic imaging, Child, Fontan Procedure, Chylothorax, Univentricular Heart, Magnetic Resonance Imaging, Retrospective Studies
Abstract

Background In the palliative pathway of single-ventricle physiology, lymphatic abnormalities on T2-weighted magnetic resonance imaging have been shown after the Glenn operation. It is believed that postsurgical hemodynamic changes contribute to the lymphatic changes.However, little is known about how early these abnormalities occur. Our purpose was to determine if lymphatic abnormalities occur as early as before the Glenn operation. Methods and Results We retrospectively reviewed patients with single-ventricle physiology and a T2-weighted magnetic resonance imaging scan before their Glenn operation (superior cavopulmonary connection) at The Children's Hospital of Philadelphia from 2012 to 2022. Lymphatic perfusion patterns on T2-magnetic resonance imaging were categorized from type 1 (no supraclavicular T2-signal) to type 4 (supraclavicular, mediastinal, lung parenchymal T2-signal). Types 1 and 2 were considered normal variants. Distribution of lymphatic abnormalities were tabulated, as well as secondary outcomes including chylothorax and mortality. Comparison was done using analysis of variance, Kruskal-Wallis test, and Fisher's exact test. Seventy-one children were included: 30 with hypoplastic left heart syndrome and 41 with nonhypoplastic left heart syndrome. Lymphatic abnormalities were present before Glenn operation in 21% (type 3) and 20% (type 4), and normal lymphatic perfusion patterns (type 1-2) were seen in 59% of patients. Chylothorax was present in 17% (only types 3 and 4). Pre-Glenn mortality and mortality at any time was significantly increased when having a type 4 lymphatic abnormality compared with types 1 and 2 (P=0.04). Conclusions Lymphatic abnormalities can be found on T2-weighted magnetic resonance imaging in children with single-ventricle physiology before their Glenn operation. Mortality and chylothorax were more prevalent with advancing grade of lymphatic abnormality.

Published
2023

26. A novel algorithm for classification of interatrial communications within the oval fossa in the newborn

Author

Dannesbo, Sofie, primary, Blixenkrone-Moeller, Elisabeth, additional, Pihl, Christian A., additional, Sillesen, Anne-Sophie, additional, Voegg, Ruth O., additional, Davidsen, Agnes S., additional, Lind, Louise E., additional, Jeppesen, Dorthe L., additional, Kruse, Charlotte, additional, Noerager, Betina, additional, Dodd, James K., additional, Jorgensen, Finn S., additional, Raja, Anna A., additional, Colan, Steven D., additional, Mertens, Luc, additional, Hjortdal, Vibeke E., additional, Vejlstrup, Niels, additional, Anderson, Robert H., additional, Bundgaard, Henning, additional, and Iversen, Kasper, additional

Published
2022
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31. Gravity and lymphodynamics

Author

Holm‐Weber, Thomas, primary, Kristensen, Rasmus Eskild, additional, Mohanakumar, Sheyanth, additional, and Hjortdal, Vibeke E., additional

Published
2022
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35. Congenital Heart Disease and the Risk of Impaired Fertility: A Danish Nationwide Cohort Study Using Time to Pregnancy

Author

Udholm, Louise F., Ebdrup, Ninna H, Arendt, Linn H, Knudsen, Ulla B, Hjortdal, Vibeke E, and Ramlau-Hansen, Cecilia H

Subjects
History, Polymers and Plastics, Infertility, Reproduction, Business and International Management, Cardiology and Cardiovascular Medicine, Time to pregnancy, Industrial and Manufacturing Engineering, Congenital heart disease
Abstract

BACKGROUND: The number of women with congenital heart disease (CHD) becoming pregnant are increasing. Although menstrual irregularities appear to occur more often in these patients, knowledge on their fertility is limited. In this nationwide cohort study, we evaluated the risk of impaired fertility in women with CHD compared with unaffected women using time to pregnancy (TTP).METHODS: The Danish National Birth Cohort (DNBC) of pregnant women constituted the study population. Information on TTP and use of medically assisted reproduction (MAR) treatment was reported at a first trimester interview. Women with CHD were identified by linkage to the Danish National Patient Registry. TTP was divided into three categories; 0-5 months, 6-12 months (i.e. subfertile), and > 12 months or use of MAR treatment (i.e. infertile). Relative risk ratios (RRR) for subfertility and infertility with 95% confidence intervals were estimated using multinomial logistic regression.RESULTS: Among 93,832 pregnancies in 84,922 women, CHD was diagnosed in 333 women (0.4%), contributing with 360 pregnancies. The CHD was of simple complexity in 291 women (87.4%). No association was found between CHD and longer TTP (RRR of 1.02 (95% CI: 0.75-1.40) for subfertility, and RRR of 0.86 (95% CI: 0.61-1.20) for infertility). Similar was observed when comparing women with simple CHD and unaffected women. The number of women with complex CHD was too low for evaluation.CONCLUSIONS: Women with CHD had no increased risk of impaired fertility, assessed by TTP, when compared with unaffected women. Separate analysis of women with complex CHD was hampered by low numbers.

Published
2022

43. Chronic foetal hypoxaemia does not cause elevation of serum markers of brain injury

Author

Omann, Camilla, primary, Lawrence, Kendall M., additional, Hunt, Mallory L., additional, Moon, James K., additional, Buchanan, Jamuna, additional, Licht, Daniel J., additional, Ittenbach, Richard F., additional, McGovern, Patrick, additional, Chen, Jonathan M., additional, Davey, Marcus, additional, Hjortdal, Vibeke E., additional, Flake, Alan W., additional, and Gaynor, J. William, additional

Published
2021
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