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252 results on '"Hirotsu C"'

1. Correlation between obesity and chronic kidney disease: is obstructive sleep apnea an interfering factor?

Author

Santos-Camilo M, Arães SP, Hirotsu C, Tufik S, and Andersen ML

Subjects
sleep apnea, visceral adipose tissue, chronic kidney disease, obesity, Therapeutics. Pharmacology, RM1-950
Abstract

Mariana Santos-Camilo, Stefanie Pires Arães, Camila Hirotsu, Sergio Tufik, Monica Levy Andersen Department of Psychobiology, Universidade Federal de São Paulo, São Paulo, Brazil The increasing prevalence of obesity can be considered an alarming issue throughout the world.1 In only 4 years, for example, the People’s Republic of China has experienced an increase in the overweight population from 29.1% to 34.4%.2 Therefore, we would like to congratulate Xu et al3 for conducting an elegant study on a less explored topic: the accumulation of visceral fat in kidney disease. The rise in obesity may result, at least in part, from changes in lifestyle, currently characterized by sedentary, poor eating, and sleep habits. The reduction in sleep duration is known to predispose individuals to obesity by increasing the white adipose tissue deposits such as visceral fat.4,5 Of note, obesity and visceral fat accumulation are etiopathological factors for both chronic kidney disease (CKD) and sleep disorders.6,7 View the original paper by Xu et al

Published
2016

3. Pulse wave amplitude drops (PWAD) : a new biomarker of cardiovascular risk in patients with obstructive sleep apnea in HypnoLaus and ISAACC cohorts

Author

Solelhac, G., primary, Sánchez-de-la-Torre, M., additional, Berger, M., additional, Hirotsu, C., additional, Marchi, N.A., additional, Waeber, A., additional, Gracia-Lavedan, E., additional, Zapater, A., additional, Bernadi, G., additional, Betta, M., additional, Marques-Vidal, P., additional, Vollenweider, P., additional, Vaucher, J., additional, Siclari, F., additional, Barbé, F., additional, and Heinzer, R., additional

Published
2022
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4. Association of sleep microstructure with incident hypertension in a population-based sample: The HypnoLaus study

Author

Berger, M., primary, Vakulin, A., additional, Hirotsu, C., additional, Marchi, N., additional, Solelhac, G., additional, Bayon, V., additional, Siclari, F., additional, Haba-Rubio, J., additional, Vaucher, J., additional, Waeber, G., additional, Vollenweider, P., additional, Marques-Vidal, P., additional, Appleton, S., additional, and Heinzer, R., additional

Published
2022
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5. Pulse wave amplitude drops (PWAD) index: a biomarker of cardiovascular risk in patients with obstructive sleep apnea in three cohorts.

Author

Solelhac, G, primary, Sánchez-De-La-Torre, M, additional, Blanchard, M, additional, Berger, M, additional, Marchi, N A, additional, Hirotsu, C, additional, Bernardi, G, additional, Betta, M, additional, Vollenweider, P, additional, Vaucher, J, additional, Zapater, A, additional, Gracia-Lavedan, E, additional, Marques-Vidal, P, additional, Barbé, F, additional, Gagnadoux, F, additional, and Heinzer, R, additional

Published
2022
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6. Association Between Sleep Microstructure and Incident Hypertension in a Population-Based Sample: The HypnoLaus Study

Author

Berger, M., Vakulin, A., Hirotsu, C., Marchi, N.A., Solelhac, G., Bayon, V., Siclari, F., Haba-Rubio, J., Vaucher, J., Vollenweider, P., Marques-Vidal, P., Lechat, B., Catcheside, P.G., Eckert, D.J., Adams, R.J., Appleton, S., and Heinzer, R.

Subjects
Male, Polysomnography, Hypertension, Humans, Sleep, REM, Electroencephalography, Female, Aged, Hypertension/diagnosis, Hypertension/epidemiology, Middle Aged, Sleep, delta power, hypertension, power spectral density, sleep architecture, sleep structure, slow wave sleep, spindle
Abstract

Background Poor sleep quality is associated with increased incident hypertension. However, few studies have investigated the impact of objective sleep structure parameters on hypertension. This study investigated the association between sleep macrostructural and microstructural parameters and incident hypertension in a middle- to older-aged sample. Methods and Results Participants from the HypnoLaus population-based cohort without hypertension at baseline were included. Participants had at-home polysomnography at baseline, allowing assessment of sleep macrostructure (nonrapid eye movement sleep stages 1, 2, and 3; rapid eye movement sleep stages; and total sleep time) and microstructure including power spectral density of electroencephalogram in nonrapid eye movement sleep and spindles characteristics (density, duration, frequency, amplitude) in nonrapid eye movement sleep stage 2. Associations between sleep macrostructure and microstructure parameters at baseline and incident clinical hypertension over a mean follow-up of 5.2 years were assessed with multiple-adjusted logistic regression. A total of 1172 participants (42% men; age 55±10 years) were included. Of these, 198 (17%) developed hypertension. After adjustment for confounders, no sleep macrostructure features were associated with incident hypertension. However, low absolute delta and sigma power were significantly associated with incident hypertension where participants in the lowest quartile of delta and sigma had a 1.69-fold (95% CI, 1.00-2.89) and 1.72-fold (95% CI, 1.05-2.82) increased risk of incident hypertension, respectively, versus those in the highest quartile. Lower spindle density (odds ratio, 0.87; 95% CI, 0.76-0.99) and amplitude (odds ratio, 0.98; 95% CI, 0.95-1.00) were also associated with higher incident hypertension. Conclusions Sleep microstructure is associated with incident hypertension. Slow-wave activity and sleep spindles, 2 hallmarks of objective sleep continuity and quality, were inversely and consistently associated with incident hypertension. This supports the protective role of sleep continuity in the development of hypertension.

Published
2022

29. Impact of short‐acting vs. standard anaesthetic agents on obstructive sleep apnoea: a randomised, controlled, triple‐blind trial.

Author

Albrecht, E., Bayon, V., Hirotsu, C., and Heinzer, R.

Abstract

Summary: Sleep apnoea is associated with negative outcomes following general anaesthesia. Current recommendations suggest using short‐acting anaesthetic agents in preference to standard agents to reduce this risk, but there is currently no evidence to support this. This randomised controlled triple‐blind trial tested the hypothesis that a combination of short‐acting agents (desflurane‐remifentanil) would reduce the postoperative impact of general anaesthesia on sleep apnoea severity compared with standard agents (sevoflurane‐fentanyl). Sixty patients undergoing hip arthroplasty under general anaesthesia were randomised to anaesthesia with desflurane‐remifentanil or sevoflurane‐fentanyl. Respiratory polygraphy was performed before surgery and on the first and third postoperative nights. The primary outcome was the supine apnoea‐hypopnoea index on the first postoperative night. Secondary outcomes were the supine apnoea‐hypopnoea index on the third postoperative night, and the oxygen desaturation index on the first and third postoperative nights. Additional outcomes included intravenous morphine equivalent consumption and pain scores on postoperative days 1, 2 and 3. Pre‐operative sleep study data were similar between groups. Mean (95%CI) values for the supine apnoea‐hypopnoea index on the first postoperative night were 18.9 (12.7–25.0) and 21.4 (14.2–28.7) events.h−1, respectively, in the short‐acting and standard anaesthesia groups (p = 0.64). Corresponding values on the third postoperative night were 28.1 (15.8–40.3) and 38.0 (18.3–57.6) events.h−1 (p = 0.34). Secondary sleep‐ and pain‐related outcomes were generally similar in the two groups. In conclusion, short‐acting anaesthetic agents did not reduce the impact of general anaesthesia on sleep apnoea severity compared with standard agents. These data should prompt an update of current recommendations. [ABSTRACT FROM AUTHOR]

Published
2021
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30. A randomised controlled trial of shoulder block vs. interscalene brachial plexus block for ventilatory function after shoulder arthroscopy.

Author

Rhyner, P., Kirkham, K., Hirotsu, C., Farron, A., and Albrecht, E.

Subjects
BRACHIAL plexus block, SHOULDER, SHOULDER surgery, RESEARCH, RESPIRATORY insufficiency, ULTRASONIC imaging, ARTHROSCOPY, BUPIVACAINE, RESEARCH methodology, NERVE block, EVALUATION research, MEDICAL cooperation, COMPARATIVE studies, RANDOMIZED controlled trials, LOCAL anesthetics, INNERVATION
Abstract

The shoulder block may impair ventilatory function and diaphragmatic movement less than the interscalene brachial plexus block. We randomly allocated 30 adults who underwent shoulder arthroscopy under general anaesthesia to ultrasound-guided shoulder block or interscalene block with 20 ml bupivacaine 0.5%. The primary outcome, rate of ultrasound-measured hemidiaphragmatic excursion < 25% of baseline 30 min after blockade, was reduced from 12/15 with brachial plexus block to 2/15 with shoulder block, a difference (95%CI) of 67% (40-93%), p < 0.001. The mean (SD) numeric rating scale pain scores at rest after shoulder block were higher than after interscalene block at two postoperative hours, 1.4 (1.2) vs. 0.3 (0.7), p = 0.02, but lower at 24 postoperative hours, 1.3 (1.3) vs. 3.4 (2.3), p = 0.008. Mean (SD) pain scores on movement in the shoulder and interscalene blocks were similar, with respective values of 1.9 (1.9) vs. 0.7 (1.2), p = 0.13 at two postoperative hours and 3.7 (2.3) vs. 5.3 (2.5), p = 0.41, at 24 postoperative hours. [ABSTRACT FROM AUTHOR]

Published
2020
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39. Can intra-oral and facial photos predict OSA in the general and clinical population?

Author

Vidigal, T., primary, Oliveira, L., additional, Moura, T., additional, Haddad, F., additional, Sutherland, K., additional, Cistulli, P., additional, Schwab, R., additional, Pack, A., additional, Magalang, U., additional, Leinwand, S., additional, Keenan, B., additional, Chen, N.-H., additional, Maislin, G., additional, Mazzotti, D., additional, Hirotsu, C., additional, Tufik, S., additional, and Bittencourt, L., additional

Published
2017
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