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371 results on '"Hirota, Masaki"'

12. Time Sensitive Networking for 5G NR Fronthauls and Massive Iot Traffic

Author

Shibata, Naotaka, primary, Zhu, Paikun, additional, Nishimura, Kazuto, additional, Yoshida, Yuki, additional, Hayashi, Kazunori, additional, Hirota, Masaki, additional, Harada, Rintaro, additional, Honda, Kazuaki, additional, Kaneko, Shin, additional, Terada, Jun, additional, and Kitayama, Ken-Ichi, additional

Published
2021
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13. ひろたまさき主要業績一覧

Author

ひろた, まさき, ヒロタ, マサキ, HIROTA, Masaki, ひろた, まさき, ヒロタ, マサキ, and HIROTA, Masaki

Published
2021

36. Immunohistochemical expression of sialyl Le-x antigen in relation to survival of patients with colorectal carcinoma

Author

Nakagoe, Tohru, Fukushima, Kiyoyasu, Hirota, Masaki, Kusano, Hiroyuki, Ayabe, Hiroyoshi, Tomita, Masao, and Kamihira, Shimeru

Subjects
Colorectal cancer -- Prognosis, Tumor markers, Health
Abstract

Background. The alterations of carbohydrate chains in cancer cell membrane can be related, not only to the formation of tumor-associated antigens, but also to cell biologic significance. There is, furthermore, a possibility of their relationship to tumor metastatic behavior and subsequent survival of patients with cancer. Recent clinical studies elucidated that a carbohydrate antigen, sialyl [Le.sup.x], is a useful tumor marker in colorectal cancer. However, the sialyl [Le.sup.x] antigen immunoreactivity in colorectal carcinoma in relation to patient survival is unknown. The aim of the study was to elucidate whether sialyl [Le.sup.x] expression in tumors was correlated with patient survival. Methods. Immunohistochemical expression of sialyl [Le.sup.x] antigen, as detected by monoclonal antibody CSLEX1, was studied in 175 specimens of primary colorectal carcinoma from 120 patients who received radical surgery. Results. The positive expression of sialyl [Le.sup.x] was observed in 87 of 120 patients (72.5%). There was no statistically significant association between the negative or positive of sialyl [Le.sup.x] and clinicopathologic factors, excluding Dukes stage and histologic type. The difference between overall 5-year survival of patients with sialyl [Le.sup.x]-negative tumors and that of patients with sialyl [Le.sup.x]-positive tumors (81.2% versus 60.6%) was statistically significant (P = 0.0263). In proportion to staining intensity that was expressed as a score based on the percentage of the total field stained positive with CSLEX1, 5-year survival of patients indicated a worse outcome (P = 0.0113). The prognostic value was then studied in a Cox regression model. Dukes stage had the strongest association with patient survival, whereas sialyl [Le.sup.x] expression was found to be the second-ranking parameter. Conclusions. When examining the expression of sialyl [Le.sup.x] antigen, as detected by monoclonal antibody CSLEX1, clinically useful information for patient survival after radical resection of colorectal cancer is given.

Published
1993

47. Learning curve for single‐incision laparoscopic totally extraperitoneal inguinal hernia repair.

Author

Wakasugi, Masaki, Nakahara, Yujiro, Hirota, Masaki, Matsumoto, Takashi, Kusu, Takashi, Takemoto, Hiroyoshi, Takachi, Ko, and Oshima, Satoshi

Subjects
INGUINAL hernia, TEACHERS' assistants, LEARNING by teaching
Abstract

Introduction: The learning curve for totally extraperitoneal repair (TEP) is longer and steeper than that for transabdominal preperitoneal repair (TAPP) due to the preperitoneal view to which the surgeon is not accustomed and the limited working space. The aim of this study was to clarify the learning curve for SILS‐TEP. Methods: A retrospective analysis of 80 consecutive patients with unilateral inguinal hernia was performed. All patients underwent elective SILS‐TEP performed by a single learning surgeon with a teaching assistant between July 2016 and March 2018 at Kinki Central Hospital. Results: The operative time decreased gradually after 20 cases and stabilized after 40 cases. The first 40 cases were categorized as the learning period group, and the remaining 40 cases were categorized as the experienced period group. More patients received antithrombotic therapy in the experienced period than in the learning period (P < 0.05). The median operative time was 107 and 60 min in the learning period and the experienced period, respectively (P < 0.05). There were no significant differences in blood loss peritoneal injury, conversion to a different procedure, postoperative hospital stay, complications, and recurrence between the two groups. No major complications or hernia recurrence were noted during follow‐up. Conclusions: The learning curve for SILS‐TEP might take 40 cases to reduce the operative time. SILS‐TEP can be performed safely by a learning surgeon with a teaching assistant. [ABSTRACT FROM AUTHOR]

Published
2019
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48. Efficacy of single‐incision laparoscopic totally extraperitoneal repair for irreducible or incarcerated inguinal hernia.

Author

Wakasugi, Masaki, Nakahara, Yujiro, Hirota, Masaki, Matsumoto, Takashi, Takemoto, Hiroyoshi, Takachi, Ko, Nishioka, Kiyonori, and Oshima, Satoshi

Subjects
INGUINAL hernia, SURGICAL emergencies, HERNIA, ILEUM
Abstract

Introduction: The aim of this study was to evaluate the efficacy of single‐incision laparoscopic surgery for totally extraperitoneal repair (SILS‐TEP) of irreducible inguinal hernias and incarcerated inguinal hernias. Methods: We performed a retrospective analysis of 194 patients, including 16 with irreducible or incarcerated hernia, who had undergone SILS‐TEP from May 2016 to December 2017 at Kinki Central Hospital. The outcomes of patients with irreducible or incarcerated hernia and those with reducible hernia were compared. For irreducible or incarcerated hernia, laparoscopic exploration with hernia reduction through an intraumbilical incision was performed. If no bowel resection was needed, one‐stage SILS‐TEP was performed. If bowel resection was required, two‐stage SILS‐TEP was performed 2–3 months after the bowel resection. Results: Of the 16 patients, 8 had an irreducible hernia, and 8 had an incarcerated hernia. The eight patients with an incarcerated hernia underwent emergency surgery, and among these patients, two needed single‐incision laparoscopic partial resection of the ileum followed by two‐stage SILS‐TEP. Fourteen patients, excluding the two patients who required single‐incision laparoscopic partial resection of the ileum, underwent laparoscopic exploration with hernia reduction followed by one‐stage SILS‐TEP. Among these 14 patients, one with an irreducible hernia required conversion to Kugel patch repair. The operative outcomes were generally comparable between the two groups. However, the operative time was longer for unilateral hernia, and more seromas were seen in the irreducible or incarcerated group. No other major complications or cases of hernia recurrence were noted in this study. Conclusions: SILS‐TEP, which offers good cosmetic results, can be safely performed for irreducible or incarcerated inguinal hernia. [ABSTRACT FROM AUTHOR]

Published
2019
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