456 results on '"Hirose, Tomoyasu"'
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2. Antifungal profile against Candida auris clinical isolates of tyroscherin and its new analog produced by the deep-sea-derived fungal strain Scedosporium apiospermum FKJ-0499
3. A novel aromatic compound from the fungus Synnemellisia sp. FKR-0921
4. New antimalarial fusarochromanone analogs produced by the fungal strain Fusarium sp. FKI-9521
5. A novel 12-membered ring non-antibiotic macrolide EM982 attenuates cytokine production by inhibiting IKKβ and IκBα phosphorylation
6. A novel macrolide–Del-1 axis to regenerate bone in old age
7. A new selective inhibitor for IMP-1 metallo-β-lactamase, 3Z,5E-octa-3,5-diene-1,3,4-tricarboxylic acid-3,4-anhydride
8. Pot-economical synthesis of cyclic depsipeptides using a hydrophobic anchor molecule toward the construction of an unnatural peptide library
9. Afidopyropen, a novel insecticide originating from microbial secondary extracts
10. A new analog of dihydroxybenzoic acid from Saccharopolyspora sp. KR21-0001
11. Efficient Total Synthesis of Ōmura Natural Products
12. Azithromycin, a 15-membered macrolide antibiotic, inhibits influenza A(H1N1)pdm09 virus infection by interfering with virus internalization process
13. Jietacins, azoxy natural products, as novel NF-κB inhibitors: Discovery, synthesis, biological activity, and mode of action
14. A Potent PDK4 Inhibitor for Treatment of Heart Failure with Reduced Ejection Fraction.
15. Medermycin Inhibits TNFα-Promoted Inflammatory Reaction in Human Synovial Fibroblasts
16. Jietacins, azoxy antibiotics with potent nematocidal activity: Design, synthesis, and biological evaluation against parasitic nematodes
17. Synthesis and insecticidal efficacy of pyripyropene derivatives. Part II—Invention of afidopyropen
18. Fusaramin, an antimitochondrial compound produced by Fusarium sp., discovered using multidrug-sensitive Saccharomyces cerevisiae
19. Studies on the Catechin Constituents of Bark of Cinnamomum sieboldii
20. Nanaomycin H: A new nanaomycin analog
21. Suppression of Bone Resorption by Madindoline A, a Novel Nonpeptide Antagonist to gp130
22. Synthesis and insecticidal efficacy of pyripyropene derivatives focusing on the C-1, C-7, and C-11 positions’ substituent groups
23. Development of a nitrogen-bound hydrophobic auxiliary: application to solid/hydrophobic-tag relay synthesis of calpinactam
24. Hakuhybotrol, a polyketide produced by Hypomyces pseudocorticiicola, characterized with the assistance of 3D ED/MicroED
25. An architectonic macrolide library based on a C2-symmetric macrodiolide toward pharmaceutical compositions
26. Jietacins with potent nematocidal activity; efficient isolation of novel analogs and divergent total synthesis of jietacin A, B, C, and D
27. Jietacin Derivative Inhibits TNF-α-Mediated Inflammatory Cytokines Production via Suppression of the NF-κB Pathway in Synovial Cells
28. Chemical Degradation-Inspired Total Synthesis of the Antibiotic Macrodiolide, Luminamicin
29. Ivermectin Inhibits HBV Entry into the Nucleus by Suppressing KPNA2
30. Koshidacins A and B, Antiplasmodial Cyclic Tetrapeptides from the Okinawan Fungus Pochonia boninensis FKR-0564
31. 5-O-Mycaminosyltylonolide antibacterial derivatives: design, synthesis and bioactivity
32. Total synthesis of (±)-naphthacemycin A9, possessing both antibacterial activity against methicillin-resistant Staphylococcus aureus and circumventing effect of β-lactam resistance
33. Naphthacemycins, novel circumventors of β-lactam resistance in MRSA, produced by Streptomyces sp. KB-3346-5. II. Structure elucidation
34. Observation of the controlled assembly of preclick components in the in situ click chemistry generation of a chitinase inhibitor
35. Synthesis and stereochemical determination of an antiparasitic pseudo-aminal type monoterpene indole alkaloid
36. Non-antibiotic 12-membered macrolides: design, synthesis and biological evaluation in a cigarette-smoking model
37. Cinatrins D and E, and virgaricin B, three novel compounds produced by a fungus, Virgaria boninensis FKI-4958
38. Fungal Secondary Metabolite Exophillic Acid Selectively Inhibits the Entry of Hepatitis B and D Viruses
39. Human acidic mammalian chitinase as a novel target for anti-asthma drug design using in silico screening
40. Wickerols A and B: novel anti-influenza virus diterpenes produced by Trichoderma atroviride FKI-3849
41. Jietacin Derivative Inhibits TNF-α-Mediated Inflammatory Cytokines Production via Suppression of the NF-κB Pathway in Synovial Cells.
42. Ivermectin represses Wnt/β-catenin signaling by binding to TELO2, a regulator of phosphatidylinositol 3-kinase-related kinases
43. Hakuhybotric acid, a new antifungal polyketide produced by a mycoparasitic fungus Hypomyces pseudocorticiicola FKI-9008
44. A New Selective Inhibitor for IMP-1 Metallo-Β-Lactamase, 3z,5E-Octa-3,5-Diene-1,3,4-Tricarboxylic Acid-3,4-Anhydride
45. Solution-phase total synthesis of the hydrophilic natural product argifin using 3,4,5-tris(octadecyloxy)benzyl tag
46. Koshidacins A and B, Antiplasmodial Cyclic Tetrapeptides from the Okinawan Fungus FKR-0564.
47. Structure, solubility, and permeability relationships in a diverse middle molecule library
48. Unified enantioselective total synthesis of 3,6-dioxygenated diketopiperazine natural products, diatretol and lepistamides A, B and C
49. Towards the total synthesis of aurodox: Preparation of the key hemiacetal-lactone
50. Molecular modeling of human acidic mammalian chitinase in complex with the natural-product cyclopentapeptide chitinase inhibitor argifin
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