631 results on '"Hirose, Akihiko"'
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2. Lack of in vivo mutagenicity of carbendazim in the liver and glandular stomach of MutaMice
3. In vivo mutagenicity assessment of orally treated tert-butyl hydroperoxide in the liver and glandular stomach of MutaMouse
4. In vivo mutagenicity assessment of styrene in MutaMouse liver and lung
5. Enhancing developmental and reproductive toxicity knowledge: A new AOP stemming from glutathione depletion
6. Formation and evaluation of mechanism-based chemical categories for regulatory read-across assessment of repeated-dose toxicity: A case of hemolytic anemia
7. Assessment of the toxicity and carcinogenicity of double-walled carbon nanotubes in the rat lung after intratracheal instillation: a two-year study
8. Two-year intermittent exposure of a multiwalled carbon nanotube by intratracheal instillation induces lung tumors and pleural mesotheliomas in F344 rats
9. Initial hazard assessment of ethyl(dimethyl)(tetradecyl)ammonium ethyl sulfate: Genotoxicity tests and combined repeated-dose and reproductive/developmental toxicity screening in rats
10. The Role of In Vivo Screening Studies in Assessing Manufactured Nanomaterials
11. Initial hazard assessment of 1,4-dichlorobutane: Genotoxicity tests, 28-day repeated-dose toxicity test, and reproductive/developmental toxicity screening test in rats
12. Analysis of Silver-containing Nanoparticles in Oysters Using Single-particle ICP-MS
13. Initial hazard assessment of benzyl salicylate: In vitro genotoxicity test and combined repeated-dose and reproductive/developmental toxicity screening test in rats
14. Initial hazard assessment of 4-benzylphenol, a structural analog of bisphenol F: Genotoxicity tests in vitro and a 28-day repeated-dose toxicity study in rats
15. Pulmonary and pleural toxicity of potassium octatitanate fibers, rutile titanium dioxide nanoparticles, and MWCNT-7 in male Fischer 344 rats
16. Comparative pulmonary toxicity of a DWCNT and MWCNT-7 in rats
17. Time-Course of Transcriptomic Change in the Lungs of F344 Rats Repeatedly Exposed to a Multiwalled Carbon Nanotube in a 2-Year Test
18. Comparative carcinogenicity study of a thick, straight-type and a thin, tangled-type multi-walled carbon nanotube administered by intra-tracheal instillation in the rat
19. Simulation-based assessment of model selection criteria during the application of benchmark dose method to quantal response data
20. 14 Carcinogenicity Risk Assessment of Various Carbon Nanotubes by Intra-Tracheal Intra-Pulmonary Spray (TIPS) Dosing Followed by 2-Year Observation
21. Derivation of subacute guidance values for chemical contaminants of drinking water quality standard in Japan
22. Risk assessment of skin lightening cosmetics containing hydroquinone
23. Carcinogenic effect of potassium octatitanate (POT) fibers in the lung and pleura of male Fischer 344 rats after intrapulmonary administration
24. Regulation of Epithelial–Mesenchymal Transition Pathway and Artificial Intelligence-Based Modeling for Pathway Activity Prediction
25. Derivation of human health hazard assessment values of 1,2-dichloroethane under the Japan Chemical Substances Control Law
26. Comparison of fetal toxicity of various multi-wall carbon nanotubes in mice
27. Additional file 1 of In vivo mutagenicity assessment of styrene in MutaMouse liver and lung
28. Development of a category approach to predict the testicular toxicity of chemical substances structurally related to ethylene glycol methyl ether
29. Mutagenic properties of dimethylaniline isomers in mice as evaluated by comet, micronucleus and transgenic mutation assays
30. A category approach to predicting the repeated-dose hepatotoxicity of allyl esters
31. Safety assessment of boron by application of new uncertainty factors and their subdivision
32. Reproductive and developmental toxicity screening test of 3-cyanopyridine in rats
33. Approaches to Quality Risk Management When Using Single-Use Systems in the Manufacture of Biologics
34. The position of the nitro group affects the mutagenicity of nitroarenes
35. Additional file 1 of Two-year intermittent exposure of a multiwalled carbon nanotube by intratracheal instillation induces lung tumors and pleural mesotheliomas in F344 rats
36. Additional file 1 of Assessment of the toxicity and carcinogenicity of double-walled carbon nanotubes in the rat lung after intratracheal instillation: a two-year study
37. Structure-Activity: Dependent Regulation of Cell Communication by Perfluorinated Fatty Acids Using in vivo and in vitro Model Systems
38. Time-dependent variation in the biodistribution of C60 in rats determined by liquid chromatography–tandem mass spectrometry
39. Two-generation reproductive toxicity study of aluminium sulfate in rats
40. Clofibric Acid Increases the Formation of Oleic Acid in Endoplasmic Reticulum of the Liver of Rats
41. Derivation of human health hazard assessment values for toluene under the Japanese Chemical Substances Control Law
42. The coronavirus-related signaling pathway networks and prediction modeling with activity plots.
43. Combined Risk Assessment of Food-derived Coumarin with in Silico Approaches
44. Molecular network analysis of RNA viral infection pathway in diffuse- and intestinal-type gastric cancer
45. The prediction of therapeutic targets and microRNA network in the coronavirus pathogenesis pathway
46. A physiologically based kinetic modeling of ethyl tert-butyl ether in humans–An illustrative application of quantitative structure-property relationship and Monte Carlo simulation
47. Absence of in vivo mutagenicity of 4,4'-oxybis(benzenesulfonohydrazide) in liver and glandular stomach of MutaTM Mouse
48. Assessment of the Toxicity and Carcinogenicity of Double-Walled Carbon Nanotubes in the Rat Lung After Intratracheal Instillation: A Two-Year Study
49. Nanosized zinc oxide particles do not promote DHPN-induced lung carcinogenesis but cause reversible epithelial hyperplasia of terminal bronchioles
50. Prenatal developmental toxicity of gavage or feeding doses of 2- sec-butyl-4,6-dinitrophenol in rats
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