188 results on '"Hinojosa, Cecilia A."'
Search Results
2. Defining the r factor for post-trauma resilience and its neural predictors
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van Rooij, Sanne J. H., Santos, Justin L., Hinojosa, Cecilia A., Ely, Timothy D., Harnett, Nathaniel G., Murty, Vishnu P., Lebois, Lauren A. M., Jovanovic, Tanja, House, Stacey L., Bruce, Steven E., Beaudoin, Francesca L., An, Xinming, Neylan, Thomas C., Clifford, Gari D., Linnstaedt, Sarah D., Germine, Laura T., Bollen, Kenneth A., Rauch, Scott L., Haran, John P., Storrow, Alan B., Lewandowski, Christopher, Musey, Jr., Paul I., Hendry, Phyllis L., Sheikh, Sophia, Jones, Christopher W., Punches, Brittany E., Swor, Robert A., Pascual, Jose L., Seamon, Mark J., Harris, Erica, Pearson, Claire, Peak, David A., Merchant, Roland C., Domeier, Robert M., Rathlev, Niels K., O’Neil, Brian J., Sanchez, Leon D., Joormann, Jutta, Pizzagalli, Diego A., Sheridan, John F., Harte, Steven E., Kessler, Ronald C., Koenen, Karestan C., McLean, Samuel A., Ressler, Kerry J., and Stevens, Jennifer S.
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- 2024
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3. Immunologic resilience and COVID-19 survival advantage
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Lee, Grace C, Restrepo, Marcos I, Harper, Nathan, Manoharan, Muthu Saravanan, Smith, Alisha M, Meunier, Justin A, Sanchez-Reilly, Sandra, Ehsan, Aamir, Branum, Anne P, Winter, Caitlyn, Winter, Lauryn, Jimenez, Fabio, Pandranki, Lavanya, Carrillo, Andrew, Perez, Graciela L, Anzueto, Antonio, Trinh, Hanh, Lee, Monica, Hecht, Joan M, Martinez-Vargas, Celida, Sehgal, Raj T, Cadena, Jose, Walter, Elizabeth A, Oakman, Kimberly, Benavides, Raymond, Pugh, Jacqueline A, Team, South Texas Veterans Health Care System COVID-19, Abdalla, Mohamed I, Adams, Sandra G, Agnew, Joseph, Ali, Saleem, Barker, Jennifer, Birdwell, Angela, Bradford, Stephen, Briggs, Heather, Corral, Judith Marin, Dacus, Jennifer J, Danaher, Patrick J, DePaul, Scott A, Dickerson, Jill, Doanne, Jollynn, Elbel, Samantha, Escamilla, Corina, Farrar, Robert, Feldman, David, Flynn, Julianne, Ford, Delvina, Foy, Joanna D, Freeman, Megan, Galley, Samantha, Garza, Maritza, Gilman, Sherraine, Gomez, Jennifer, Goyal, Varun K, Grassmuck, Sally, Hanson, Joshua, Harris, Brande, Hastings, Gabrielyd, Haywood, Audrey, Hinojosa, Cecilia, Ho, Tony T, Hopkins, Teri, Jewell, Pamela, Johnson, Thomas B, Kotogiannes, Vasiliki, Lawler, Austin C, Lester, Chadwick S, Levine, Stephanie M, Lewis, Haidee V, Louder, Angel, Mainor, Charmaine, Maldonado, Rachel, Martinez, Yvette, McElligott, Neil, Medlin, Laura, Mireles, Myra, Morneau, Kathleen, Munro, Samuel B, Nambiar, Anoop, Nassery, Daniel, Nathanson, Robert, O’Rorke, Jane, Padgett, Cheryl, Pascual-Guardia, Sergi, Patterson, Marisa, Perez, Rogelio, Phillips, Robert E, Polk, Patrick B, Pomager, Michael A, Preston, Kristy J, Proud, Kevin C, Rangel, Michelle, Ratcliffe, Temple A, Reichelderfer, Renee L, Renz, Evan M, Ross, Jeanette, Rudd, Teresa, Sanchez, Maria E, Sanders, Tammy, and Schindler, Kevin C
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Biomedical and Clinical Sciences ,Clinical Sciences ,Lung ,Infectious Diseases ,Genetics ,Clinical Research ,Emerging Infectious Diseases ,Aging ,Coronaviruses ,2.1 Biological and endogenous factors ,6.1 Pharmaceuticals ,2.4 Surveillance and distribution ,Good Health and Well Being ,Adult ,Aged ,COVID-19 ,Cohort Studies ,Disease Resistance ,Female ,HIV Infections ,HIV-1 ,Humans ,Immunocompetence ,Interleukin-6 ,Longitudinal Studies ,Male ,Middle Aged ,Prospective Studies ,Respiratory Insufficiency ,SARS-CoV-2 ,Severity of Illness Index ,Sex Factors ,Survival Analysis ,T-Lymphocytes ,Transcriptome ,United States ,Viral Load ,AIDS ,biomarkers ,HIV ,immune ,inflammation ,influenza ,South Texas Veterans Health Care System COVID-19 Team ,Immunology ,Allergy - Abstract
BackgroundThe risk of severe coronavirus disease 2019 (COVID-19) varies significantly among persons of similar age and is higher in males. Age-independent, sex-biased differences in susceptibility to severe COVID-19 may be ascribable to deficits in a sexually dimorphic protective attribute that we termed immunologic resilience (IR).ObjectiveWe sought to examine whether deficits in IR that antedate or are induced by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection independently predict COVID-19 mortality.MethodsIR levels were quantified with 2 novel metrics: immune health grades (IHG-I [best] to IHG-IV) to gauge CD8+ and CD4+ T-cell count equilibrium, and blood gene expression signatures. IR metrics were examined in a prospective COVID-19 cohort (n = 522); primary outcome was 30-day mortality. Associations of IR metrics with outcomes in non-COVID-19 cohorts (n = 13,461) provided the framework for linking pre-COVID-19 IR status to IR during COVID-19, as well as to COVID-19 outcomes.ResultsIHG-I, tracking high-grade equilibrium between CD8+ and CD4+ T-cell counts, was the most common grade (73%) among healthy adults, particularly in females. SARS-CoV-2 infection was associated with underrepresentation of IHG-I (21%) versus overrepresentation (77%) of IHG-II or IHG-IV, especially in males versus females (P < .01). Presentation with IHG-I was associated with 88% lower mortality, after controlling for age and sex; reduced risk of hospitalization and respiratory failure; lower plasma IL-6 levels; rapid clearance of nasopharyngeal SARS-CoV-2 burden; and gene expression signatures correlating with survival that signify immunocompetence and controlled inflammation. In non-COVID-19 cohorts, IR-preserving metrics were associated with resistance to progressive influenza or HIV infection, as well as lower 9-year mortality in the Framingham Heart Study, especially in females.ConclusionsPreservation of immunocompetence with controlled inflammation during antigenic challenges is a hallmark of IR and associates with longevity and AIDS resistance. Independent of age, a male-biased proclivity to degrade IR before and/or during SARS-CoV-2 infection predisposes to severe COVID-19.
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- 2021
4. Reward Neurocircuitry Predicts Longitudinal Changes in Alcohol Use Following Trauma Exposure
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Hinojosa, Cecilia A., van Rooij, Sanne J.H., Fani, Negar, Ellis, Robyn A., Harnett, Nathaniel G., Lebois, Lauren A.M., Ely, Timothy D., Jovanovic, Tanja, Murty, Vishnu P., House, Stacey L., Beaudoin, Francesca L., An, Xinming, Neylan, Thomas C., Clifford, Gari D., Linnstaedt, Sarah D., Germine, Laura T., Rauch, Scott L., Haran, John P., Storrow, Alan B., Lewandowski, Christopher, Musey, Paul I., Jr., Hendry, Phyllis L., Sheikh, Sophia, Jones, Christopher W., Punches, Brittany E., Hudak, Lauren A., Pascual, Jose L., Seamon, Mark J., Harris, Erica, Pearson, Claire, Peak, David A., Merchant, Roland C., Domeier, Robert M., Rathlev, Niels K., O’Neil, Brian J., Sergot, Paulina, Bruce, Steven E., Pizzagalli, Diego A., Sheridan, John F., Harte, Steven E., Koenen, Karestan C., Kessler, Ronald C., McLean, Samuel A., Ressler, Kerry J., and Stevens, Jennifer S.
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- 2024
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5. Author Correction: Defining the r factor for post-trauma resilience and its neural predictors
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van Rooij, Sanne J. H., Santos, Justin L., Hinojosa, Cecilia A., Ely, Timothy D., Harnett, Nathaniel G., Murty, Vishnu P., Lebois, Lauren A. M., Jovanovic, Tanja, House, Stacey L., Bruce, Steven E., Beaudoin, Francesca L., An, Xinming, Neylan, Thomas C., Clifford, Gari D., Linnstaedt, Sarah D., Germine, Laura T., Bollen, Kenneth A., Rauch, Scott L., Haran, John P., Storrow, Alan B., Lewandowski, Christopher, Musey, Jr., Paul I., Hendry, Phyllis L., Sheikh, Sophia, Jones, Christopher W., Punches, Brittany E., Swor, Robert A., Pascual, Jose L., Seamon, Mark J., Harris, Erica, Pearson, Claire, Peak, David A., Merchant, Roland C., Domeier, Robert M., Rathlev, Niels K., O’Neil, Brian J., Sanchez, Leon D., Joormann, Jutta, Pizzagalli, Diego A., Sheridan, John F., Harte, Steven E., Kessler, Ronald C., Koenen, Karestan C., McLean, Samuel A., Ressler, Kerry J., and Stevens, Jennifer S.
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- 2024
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6. Validating the primary care posttraumatic stress disorder screen for DSM-5 (PC-PTSD-5) in a substance misusing, trauma-exposed, socioeconomically vulnerable population
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Patton, Samantha C., Hinojosa, Cecilia A., Lathan, Emma C., Welsh, Justine W., and Powers, Abigail
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- 2023
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7. Bacterial Patterns and Empiric Antibiotic Use in COPD Patients With Community-Acquired Pneumonia
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Aruj, Patricia Karina, Attorri, Silvia, Barimboim, Enrique, Caeiro, Juan Pablo, Garzón, María I., Cambursano, Victor Hugo, Ceccato, Adrian, Chertcoff, Julio, Lascar, Florencia, Tulio, Fernando Di, Díaz, Ariel Cordon, Vedia, Lautaro de, Ganaha, Maria Cristina, Lambert, Sandra, Lopardo, Gustavo, Luna, Carlos M., Malberti, Alessio Gerardo, Morcillo, Nora, Tartara, Silvina, Pensotti, Claudia, Pereyra, Betiana, Scapellato, Pablo Gustavo, Stagnaro, Juan Pablo, Shah, Sonali, Lötsch, Felix, Thalhammer, Florian, Anseeuw, Kurt, Francois, Camille A., Braeckel, Eva Van, Vincent, Jean Louis, Djimon, Marcel Zannou, Bashi, Jules, Dodo, Roger, Nouér, Simone Aranha, Chipev, Peter, Encheva, Milena, Miteva, Darina, Petkova, Diana, Balkissou, Adamou Dodo, Pefura Yone, Eric Walter, Mbatchou Ngahane, Bertrand Hugo, Shen, Ning, Xu, Jin-fu, Bustamante Rico, Carlos Andres, Buitrago, Ricardo, Pereira Paternina, Fernando Jose, Kayembe Ntumba, Jean-Marie, Carevic, Vesna Vladic, Jakopovic, Marko, Jankovic, Mateja, Matkovic, Zinka, Mitrecic, Ivan, Bouchy Jacobsson, Marie-Laure, Christensen, Anette Bro, Bødtger, Uffe, Meyer, Christian Niels, Jensen, Andreas Vestergaard, Baunbæk-knudsen, Gertrud, Petersen, Pelle Trier, Andersen, Stine, Abd El-Wahhab, Ibrahim El-Said, Morsy, Nesreen Elsayed, Shafiek, Hanaa, Sobh, Eman, Abdulsemed, Kedir Abdella, Bertrand, Fabrice, Brun-Buisson, Christian, Montmollin, Etienne de, Fartoukh, Muriel, Messika, Jonathan, Tattevin, Pierre, Khoury, Abdo, Ebruke, Bernard, Dreher, Michael, Kolditz, Martin, Meisinger, Matthias, Pletz, Mathias W., Hagel, Stefan, Rupp, Jan, Schaberg, Tom, Spielmanns, Marc, Creutz, Petra, Suttorp, Norton, Siaw-Lartey, Beatrice, Dimakou, Katerina, Gaga, Mina, Papapetrou, Dimosthenis, Tsigou, Evdoxia, Ampazis, Dimitrios, Kaimakamis, Evangelos, Bhatia, Mohit, Dhar, Raja, D'Souza, George, Garg, Rajiv, Koul, Parvaiz A., Mahesh, P.A., Jayaraj, B.S., Narayan, Kiran Vishnu, Udnur, Hirennappa B., Krishnamurthy, Shashi Bhaskara, Kant, Surya, Swarnakar, Rajesh, Limaye, Sneha, Salvi, Sundeep, Golshani, Keihan, Keatings, Vera M., Martin-Loeches, Ignacio, Maor, Yasmin, Strahilevitz, Jacob, Battaglia, Salvatore, Carrabba, Maria, Ceriana, Piero, Confalonieri, Marco, Monforte, Antonella d’Arminio, Prato, Bruno Del, Rosa, Marino De, Fantini, Riccardo, Faverio, Paola, Fiorentino, Giuseppe, Gammino, Maria Antonia, Menzella, Francesco, Milani, Giuseppe, Nava, Stefano, Palmiero, Gerardo, Petrino, Roberta, Gabrielli, Barbara, Rossi, Paolo, Sorino, Claudio, Steinhilber, Gundi, Zanforlin, Alessandro, Franzetti, Fabio, Carugati, Manuela, Morosi, Manuela, Monge, Elisa, Carone, Mauro, Patella, Vincenzo, Scarlata, Simone, Comel, Andrea, Kurahashi, Kiyoyasu, Bacha, Zeina Aoun, Ugalde, Daniel Barajas, Zuñiga, Omar Ceballos, Villegas, José F., Medenica, Milic, Garde, E.M.W. van de, Mihsra, Deebya Raj, Shrestha, Poojan, Ridgeon, Elliott, Awokola, Babatunde Ishola, Nwankwo, Ogonna N.O., Olufunlola, Adefuye Bolanle, Olumide, Segaolu, Ukwaja, Kingsley N., Irfan, Muhammad, Minarowski, Lukasz, Szymon, Skoczyński, Froes, Felipe, Leuschner, Pedro, Meireles, Mariana, Ferrão, Cláudia, Neves, João, Ravara, Sofia B., Brocovschii, Victoria, Ion, Chesov, Rusu, Doina, Toma, Cristina, Chirita, Daniela, Dorobat, Carmen Mihaela, Birkun, Alexei, Kaluzhenina, Anna, Almotairi, Abdullah, Ali Bukhary, Zakeya Abdulbaqi, Edathodu, Jameela, Fathy, Amal, Abdulaziz Enani, Abdullah Mushira, Mohamed, Nazik Eltayeb, Memon, Jawed Ulhadi, Bella, Abdelhaleem, Bogdanović, Nada, Milenkovic, Branislava, Pesut, Dragica, Borderìas, Luis, Bordon Garcia, Noel Manuel, Alarcón, Hugo Cabello, Cilloniz, Catia, Torres, Antoni, Diaz-Brito, Vicens, Casas, Xavier, González, Alicia Encabo, Fernández-Almira, Maria Luisa, Gallego, Miguel, Gaspar-García, Inmaculada, Castillo, Juan González del, Victoria, Patricia Javaloyes, Martínez, Elena Laserna, Molina, Rosa Malo de, Marcos, Pedro J., Menéndez, Rosario, Pando-Sandoval, Ana, Aymerich, Cristina Prat, Torre, Alicia Lacoma de la, García-Olivé, Ignasi, Rello, Jordi, Moyano, Silvia, Sanz, Francisco, Sibila, Oriol, Rodrigo-Troyano, Ana, Solé-Violán, Jordi, Uranga, Ane, Boven, Job F.M. van, Torra, Ester Vendrell, Pujol, Jordi Almirall, Feldman, Charles, Yum, Ho Kee, Fiogbe, Arnauld Attannon, Yangui, Ferdaous, Bilaceroglu, Semra, Dalar, Levent, Yilmaz, Ufuk, Bogomolov, Artemii, Elahi, Naheed, Dhasmana, Devesh J., Feneley, Andrew, Ions, Rhiannon, Skeemer, Julie, Woltmann, Gerrit, Hancock, Carole, Hill, Adam T., Rudran, Banu, Ruiz-Buitrago, Silvia, Campbell, Marion, Whitaker, Paul, Youzguin, Alexander, Singanayagam, Anika, Allen, Karen S., Brito, Veronica, Dietz, Jessica, Dysart, Claire E., Kellie, Susan M., Franco-Sadud, Ricardo A., Meier, Garnet, Holland, Thomas L., Bergin, Stephen P., Kheir, Fayez, Landmeier, Mark, Lois, Manuel, Nair, Girish B., Patel, Hemali, Reyes, Katherine, Rodriguez-Cintron, William, Saito, Shigeki, Soni, Nilam J., Noda, Julio, Hinojosa, Cecilia I., Levine, Stephanie M., Angel, Luis F., Reyes, Luis F., Anzueto, Antonio, Whitlow, K. Scott, Hipskind, John, Sukhija, Kunal, Totten, Vicken, Wunderink, Richard G., Shah, Ray D., Mateyo, Kondwelani John, Noriega, Lorena, Alvarado, Ezequiel, Aman, Mohamed, Labra, Lucía, Pascual-Guardia, Sergi, Amati, Francesco, Marin-Corral, Judith, Aliberti, Stefano, Gea, Joaquim, Rodriguez, Alejandro, Sotgiu, Giovanni, Meyer, Christian N., Anzueto, Antonio R., and Restrepo, Marcos I.
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- 2023
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8. Exaggerated amygdala activation to ambiguous facial expressions is a familial vulnerability factor for posttraumatic stress disorder
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Hinojosa, Cecilia A., VanElzakker, Michael B., Hughes, Katherine C., Offringa, Reid, Sangermano, Lisa M., Spaulding, Isabella G., Staples-Bradley, Lindsay K., Whitman, Ethan T., Lasko, Natasha B., Rauch, Scott L., Orr, Scott P., Pitman, Roger K., and Shin, Lisa M.
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- 2022
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9. The Relations Among Childhood Maltreatment and Later Intimate Partner Violence Victimization With and Without a Weapon in a Sample of Pregnant Black Individuals.
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Huibregtse, Megan E., Wallace, Shimarith, Ravi, Meghna, Karra, Sriya, McAfee, Elizabeth E., Hinojosa, Cecilia A., Mekawi, Yara, Powers, Abigail, Michopoulos, Vasiliki, and Lathan, Emma C.
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PUBLIC hospitals ,RISK assessment ,INTIMATE partner violence ,AFRICAN Americans ,SAFETY-net health care providers ,RESEARCH funding ,ADULT child abuse victims ,DATA analysis ,CHILD abuse ,WEAPONS ,LOGISTIC regression analysis ,QUESTIONNAIRES ,SOCIOECONOMIC factors ,HEALTH insurance ,PREGNANT women ,PSYCHOLOGY of women ,DESCRIPTIVE statistics ,MANN Whitney U Test ,AGE distribution ,CRIME victims ,PRENATAL care ,CHILD sexual abuse ,ODDS ratio ,STATISTICS ,CONFIDENCE intervals ,DATA analysis software ,EDUCATIONAL attainment ,EMPLOYMENT - Abstract
Black pregnant and postpartum individuals are at risk for intimate partner violence (IPV), and those with a history of childhood maltreatment and IPV are even more likely to be re-victimized during pregnancy. However, it is unknown if specific types of child maltreatment predict later IPV with and without a weapon better than others. The current study sought to (i) document the prevalence of childhood maltreatment and IPV and (ii) examine the relations among types of childhood maltreatment and later IPV with and without a weapon within a sample of Black individuals seeking prenatal care at a large public hospital in the southeastern United States. Participants (n = 186; mean age = 27.2 years, SD = 5.3) completed measures assessing childhood maltreatment and IPV with and without a weapon. Approximately 68.5% of participants (n = 124) endorsed experiencing childhood maltreatment, while 42.6% (n = 78) endorsed experiencing IPV. The bivariate relations among five childhood maltreatment types (i.e., sexual, physical, and emotional abuse, physical and emotional neglect) and IPV with and without a weapon were assessed. All childhood maltreatment subtype scores—except childhood physical neglect—were significantly higher among participants who reported a history of IPV with or without a weapon compared to participants who denied a history of IPV with or without a weapon. Logistic regression models revealed childhood sexual abuse emerged as the only significant predictor of experiencing IPV with a weapon (B = 0.10, p =.003) and IPV without a weapon (B = 0.11, p =.001). For every point increase in childhood sexual abuse subtype score, the odds of experiencing IPV with and without a weapon increased by 10% (OR = 1.10, 95%CI [1.04, 1.18]) and 12% (OR = 1.12, [1.05, 1.20]), respectively. Findings suggest that screening for childhood sexual abuse may provide a critical opportunity for maternity care providers to identify individuals at increased risk for IPV victimization with and without a weapon. [ABSTRACT FROM AUTHOR]
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- 2025
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10. Immunologic resilience and COVID-19 survival advantage
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Abdalla, Mohamed I., Adams, Sandra G., Agnew, Joseph, Ali, Saleem, Barker, Jennifer, Birdwell, Angela, Bradford, Stephen, Briggs, Heather, Marin Corral, Judith, Dacus, Jennifer J., Danaher, Patrick J., DePaul, Scott A., Dickerson, Jill, Doanne, Jollynn, Elbel, Samantha, Escamilla, Corina, Farrar, Robert, Feldman, David, Flynn, Julianne, Ford, Delvina, Foy, Joanna D., Freeman, Megan, Galley, Samantha, Garza, Maritza, Gilman, Sherraine, Gomez, Jennifer, Goyal, Varun K., Grassmuck, Sally, Hanson, Joshua, Harris, Brande, Hastings, Gabrielyd, Haywood, Audrey, Hinojosa, Cecilia, Ho, Tony T., Hopkins, Teri, Jewell, Pamela, Johnson, Thomas B., Kotogiannes, Vasiliki, Lawler, Austin C., Lester, Chadwick S., Levine, Stephanie M., Lewis, Haidee V., Louder, Angel, Mainor, Charmaine, Maldonado, Rachel, Martinez, Yvette, McElligott, Neil, Medlin, Laura, Mireles, Myra, Morneau, Kathleen, Munro, Samuel B., Nambiar, Anoop, Nassery, Daniel, Nathanson, Robert, O’Rorke, Jane, Padgett, Cheryl, Pascual-Guardia, Sergi, Patterson, Marisa, Perez, Rogelio, Phillips, Robert E., Polk, Patrick B., Pomager, Michael A., Preston, Kristy J., Proud, Kevin C., Rangel, Michelle, Ratcliffe, Temple A., Reichelderfer, Renee L., Renz, Evan M., Ross, Jeanette, Rudd, Teresa, Sanchez, Maria E., Sanders, Tammy, Schindler, Kevin C., Schmit, David, Solorzano, Claudio, Soni, Nilam, Tam, Win S., Tovar, Edward J., Tyler, Anna R., Vasquez, Anjuli, Veloso, Maria C., Venticinque, Steven G., Villalpando, Jorge A., Villanueva, Melissa, Villegas, Lauren, Wallace, Andrew, Wang, Emily, Williamson, Andreia, Trammell Velasquez, Sadie A., Yunes, Andrea, Zentner, Katharine H., Lee, Grace C., Restrepo, Marcos I., Harper, Nathan, Manoharan, Muthu Saravanan, Smith, Alisha M., Meunier, Justin A., Sanchez-Reilly, Sandra, Ehsan, Aamir, Branum, Anne P., Winter, Caitlyn, Winter, Lauryn, Jimenez, Fabio, Pandranki, Lavanya, Carrillo, Andrew, Perez, Graciela L., Anzueto, Antonio, Trinh, Hanh, Lee, Monica, Hecht, Joan M., Martinez-Vargas, Celida, Sehgal, Raj T., Cadena, Jose, Walter, Elizabeth A., Oakman, Kimberly, Benavides, Raymond, Pugh, Jacqueline A., Letendre, Scott, Steri, Maristella, Orrù, Valeria, Fiorillo, Edoardo, Cucca, Francesco, Moreira, Alvaro G., Zhang, Nu, Leadbetter, Elizabeth, Agan, Brian K., Richman, Douglas D., He, Weijing, Clark, Robert A., Okulicz, Jason F., and Ahuja, Sunil K.
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- 2021
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11. Aspiration Risk Factors, Microbiology, and Empiric Antibiotics for Patients Hospitalized With Community-Acquired Pneumonia
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Aruj, Patricia Karina, Attorri, Silvia, Barimboim, Enrique, Caeiro, Juan Pablo, Garzón, María I., Cambursano, Victor Hugo, Adrian Ceccato, V. H. Dr Cazaux A., Chertcoff, Julio, Lascar, Florencia, Di Tulio, Fernando, Díaz, Ariel Cordon, de Vedia, Lautaro, Ganaha, Maria Cristina, Lambert, Sandra, Lopardo, Gustavo, Luna, Carlos M., Malberti, Alessio Gerardo, Morcillo, Nora, Tartara, Silvina, Pensotti, Claudia, Pereyra, Betiana, Scapellato, Pablo Gustavo, Stagnaro, Juan Pablo, Shah, Sonali, Lötsch, Felix, Thalhammer, Florian, Anseeuw, Kurt, Francois, Camille A., Van Braeckel, Eva, Vincent, Jean Louis, Djimon, Marcel Zannou, Bashi, Jules, Dodo, Roger, Nouér, Simone Aranha, Chipev, Peter, Encheva, Milena, Miteva, Darina, Petkova, Diana, Balkissou, Adamou Dodo, Pefura Yone, Eric Walter, Mbatchou Ngahane, Bertrand Hugo, Shen, Ning, Xu, Jin-fu, Bustamante Rico, Carlos Andres, Buitrago, Ricardo, Pereira Paternina, Fernando Jose, Kayembe Ntumba, Jean-Marie, Carevic, Vesna Vladic, Jakopovic, Marko, Jankovic, Mateja, Matkovic, Zinka, Mitrecic, Ivan, Bouchy Jacobsson, Marie-Laure, Christensen, Anette Bro, Heitmann Bødtger, Uffe Christian, Meyer, Christian Niels, Jensen, Andreas Vestergaard, Baunbæk-knudsen, Gertrud, Petersen, Pelle Trier, Andersen, Stine, El-Said Abd El-Wahhab, Ibrahim, Morsy, Nesreen Elsayed, Shafiek, Hanaa, Sobh, Eman, Abdulsemed, Kedir Abdella, Bertrand, Fabrice, Brun-Buisson, Christian, de Montmollin, Etienne, Fartoukh, Muriel, Messika, Jonathan, Tattevin, Pierre, Khoury, Abdo, Ebruke, Bernard, Dreher, Michael, Kolditz, Martin, Meisinger, Matthias, Pletz, Mathias W., Hagel, Stefan, Rupp, Jan, Schaberg, Tom, Spielmanns, Marc, Creutz, Petra, Suttorp, Norton, Siaw-Lartey, Beatrice, Papapetrou, Dimosthenis, Tsigou, Evdoxia, Ampazis, Dimitrios, Kaimakamis, Evangelos, Bhatia, Mohit, Dhar, Raja, D’Souza, George, Garg, Rajiv, Koul, Parvaiz A., Mahesh, P.A., Jayaraj, B.S., Narayan, Kiran Vishnu, Udnur, Hirennappa B., Krishnamurthy, Shashi Bhaskara, Kant, Surya, Swarnakar, Rajesh, Limaye, Sneha, Salvi, Sundeep, Golshani, Keihan, Keatings, Vera M., Martin-Loeches, Ignacio, Maor, Yasmin, Strahilevitz, Jacob, Faverio, Paola, Battaglia, Salvatore, Carrabba, Maria, Ceriana, Piero, Confalonieri, Marco, Monforte, Antonella d’Arminio, Del Prato, Bruno, De Rosa, Marino, Fantini, Riccardo, Fiorentino, Giuseppe, Gammino, Maria Antonia, Menzella, Francesco, Milani, Giuseppe, Nava, Stefano, Palmiero, Gerardo, Gabrielli, Barbra, Rossi, Paolo, Sorino, Claudio, Steinhilber, Gundi, Zanforlin, Alessandro, San Luca, Ospedale, Franzetti, Fabio, Carugati, Manuela, Morosi, Manuela, Monge, Elisa, Carone, Mauro, Patella, Vincenzo, Scarlata, Simone, Comel, Andrea, Kurahashi, Kiyoyasu, Bacha, Zeina Aoun, Ugalde, Daniel Barajas, Zuñiga, Omar Ceballos, Villegas, José F., Medenica, Milic, Mihsra, Deebya Raj, Shrestha, Poojan, Ridgeon, Elliott, Awokola, Babatunde Ishola, Adefuye Bolanle Olufunlola, Ogonna N.O., Olumide, Segaolu, Ukwaja, Kingsley N., Irfan, Muhammad, Minarowski, Lukasz, Szymon, Skoczyński, Froes, Felipe, Leuschner, Pedro, Meireles, Mariana, Ferrão, Cláudia, Neves, João, Abel Salazar, Ravara, Sofia B., Brocovschii, Victoria, Rusu, Doina, Toma, Cristina, Chirita, Daniela, Dorobat, Carmen Mihaela, Birkun, Alexei, Kaluzhenina, Anna, Almotairi, Abdullah, Ali Bukhary, Zakeya Abdulbaqi, Edathodu, Jameela, Fathy, Amal, Abdulaziz Enani, Abdullah Mushira, Mohamed, Nazik Eltayeb, Memon, Jawed Ulhadi, Bella, Abdelhaleem, Bogdanović, Serbia: Nada, Milenkovic, Branislava, Pesut, Dragica, Borderìas, Luis, Bordon Garcia, Noel Manuel, Alarcón, Hugo Cabello, Cilloniz, Catia, Torres, Antoni, Diaz-Brito, Vicens, Casas, Xavier, González, Alicia Encabo, Fernández-Almira, Maria Luisa, Interna, Medicina, Gallego, Miguel, Gaspar-GarcÍa, Inmaculada, González del Castillo, Juan, Victoria, Patricia Javaloyes, Martínez, Elena Laserna, Malo de Molina, Rosa, Marcos, Pedro J., Menéndez, Rosario, Pando-Sandoval, Ana, Aymerich, Cristina Prat, Lacoma de la Torre, Alicia, García-Olivé, Ignasi, Rello, Jordi, Moyano, Silvia, Rodrigo-Troyano, Ana, Solé-Violán, Jordi, Uranga, Ane, van Boven, Job FM., Torra, Ester Vendrell, Pujol, Jordi Almirall, Feldman, Charles, Yum, Ho Kee, Arnauld Attannon Fiogbe, Inje Univ., Yangui, Ferdaous, Bilaceroglu, Semra, Levent Dalar, Izmir Dr., Yilmaz, Ufuk, Bogomolov, Artemii, Elahi, Naheed, Dhasmana, Devesh J., Feneley, Andrew, Hill, Adam T., Rudran, Banu, Ruiz-Buitrago, Silvia, Campbell, Marion, Whitaker, Paul, Youzguin, Alexander, Singanayagam, Anika, Hancock, C., Villafuerte, David, Allen, Karen S., Brito, Veronica, Dietz, Jessica, Dysart, Claire E., Kellie, Susan M., Ricardo A. Franco-Sadud, Clement J., Meier, Garnet, Gaga, Mina, Holland, Thomas L., Bergin, Stephen P., Kheir, Fayez, Landmeier, Mark, Lois, Manuel, Nair, Girish B., Patel, Hemali, Reyes, Katherine, Rodriguez-Cintron, William, Saito, Shigeki, Noda, Julio, Hinojosa, Cecilia I., Levine, Stephanie M., Reyes, Luis F., Angel, Luis F., Anzueto, Antonio, Whitlow, K. Scott, Hipskind, John, Sukhija, Kunal, Totten, Vicken, Wunderink, Richard G., Shah, Ray D., Mateyo, Kondwelani John, Noriega, Lorena, Alvarado, Ezequiel, Aman, Mohamed, Labra, Lucía, Marin-Corral, Judith, Pascual-Guardia, Sergi, Amati, Francesco, Aliberti, Stefano, Masclans, Joan R., Soni, Nilam, Rodriguez, Alejandro, Sibila, Oriol, Sanz, Francisco, Sotgiu, Giovanni, Dimakou, Katerina, Petrino, Roberta, van de Garde, Ewoudt, and Restrepo, Marcos I.
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- 2021
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12. The Relations Among Childhood Maltreatment and Later Intimate Partner Violence Victimization With and Without a Weapon in a Sample of Pregnant Black Individuals
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Huibregtse, Megan E., primary, Wallace, Shimarith, additional, Ravi, Meghna, additional, Karra, Sriya, additional, McAfee, Elizabeth E., additional, Hinojosa, Cecilia A., additional, Mekawi, Yara, additional, Powers, Abigail, additional, Michopoulos, Vasiliki, additional, and Lathan, Emma C., additional
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- 2024
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13. Does Hippocampal Volume in Patients with Posttraumatic Stress Disorder Vary by Trauma Type?
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Hinojosa, Cecilia A.
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- 2022
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14. Functional Domains of Substance Use and their Implications to Trauma: A Systematic Review of Neuroimaging Studies
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Hinojosa, Cecilia A., primary, Sitar, Siara I., additional, Zhao, Joshua C., additional, Barbosa, Joshua D., additional, Hien, Denise A., additional, Welsh, Justine W., additional, Fani, Negar, additional, and van Rooij, Sanne J.H., additional
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- 2024
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15. An international perspective on hospitalized patients with viral community-acquired pneumonia
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Aruj, Patricia Karina, Attorri, Silvia, Barimboim, Enrique, Caeiro, Juan Pablo, Garzón, María I., Cambursano, Victor Hugo, Ceccato, Adrian, Chertcoff, Julio, Cordon Díaz, Ariel, de Vedia, Lautaro, Ganaha, Maria Cristina, Lambert, Sandra, Lopardo, Gustavo, Luna, Carlos M., Malberti, Alessio Gerardo, Morcillo, Nora, Tartara, Silvina, Pensotti, Claudia, Pereyra, Betiana, Scapellato, Pablo Gustavo, Stagnaro, Juan Pablo, Shah, Sonali, Lötsch, Felix, Thalhammer, Florian, Anseeuw, Kurt, Francois, Camille A., Van Braeckel, Eva, Vincent, Jean Louis, Djimon, Marcel Zannou, Aranha Nouér, Simone, Chipev, Peter, Encheva, Milena, Miteva, Darina, Petkova, Diana, Balkissou, Adamou Dodo, Pefura Yone, Eric Walter, Mbatchou Ngahane, Bertrand Hugo, Shen, Ning, Xu, Jin-fu, Bustamante Rico, Carlos Andres, Buitrago, Ricardo, Pereira Paternina, Fernando Jose, Kayembe Ntumba, Jean-Marie, Vladic-Carevic, Vesna, Jakopovic, Marko, Matkovic, Zinka, Mitrecic, Ivan, Bouchy Jacobsson, Marie-Laure, Bro Christensen, Anette, Bødtger, Uffe, Meyer, Christian Niels, Vestergaard Jensen, Andreas, El-Said Abd El-Wahhab, Ibrahim, Elsayed Morsy, Nesreen, Shafiek, Hanaa, Sobh, Eman, Abdulsemed, Kedir Abdella, Bertrand, Fabrice, Brun-Buisson, Christian, de Montmollin, Etienne, Fartoukh, Muriel, Messika, Jonathan, Tattevin, Pierre, Khoury, Abdo, Ebruke, Bernard, Dreher, Michael, Kolditz, Martin, Meisinger, Matthias, Pletz, Mathias W., Hagel, Stefan, Rupp, Jan, Schaberg, Tom, Spielmanns, Marc, Creutz, Petra, Suttorp, Norton, Siaw-Lartey, Beatrice, Dimakou, Katerina, Papapetrou, Dimosthenis, Tsigou, Evdoxia, Ampazis, Dimitrios, Kaimakamis, Evangelos, Bhatia, Mohit, Dhar, Raja, D’Souza, George, Garg, Rajiv, Koul, Parvaiz A., Jayaraj, B.S., Narayan, Kiran Vishnu, Udnur, Hirennappa B., Krishnamurthy, Shashi Bhaskara, Kant, Surya, Swarnakar, Rajesh, Salvi, Sundeep, Limaye, Sneha, Golshani, Keihan, Keatings, Vera M., Martin-Loeches, Ignacio, Maor, Yasmin, Strahilevitz, Jacob, Battaglia, Salvatore, Carrabba, Maria, Ceriana, Piero, Confalonieri, Marco, d’Arminio Monforte, Antonella, Del Prato, Bruno, De Rosa, Marino, Fantini, Riccardo, Fiorentino, Giuseppe, Gammino, Maria Antonia, Menzella, Francesco, Milani, Giuseppe, Nava, Stefano, Palmiero, Gerardo, Petrino, Roberta, Gabrielli, Barbra, Rossi, Paolo, Sorino, Claudio, Steinhilber, Gundi, Zanforlin, Alessandro, Franzetti, Fabio, Carone, Mauro, Patella, Vincenzo, Scarlata, Simone, Comel, Andrea, Kurahashi, Kiyoyasu, Aoun Bacha, Zeina, Barajas Ugalde, Daniel, Ceballos Zuñiga, Omar, Villegas, José F., Medenica, Milic, van de Garde, E.M.W., Raj Mihsra, Deebya, Shrestha, Poojan, Ridgeon, Elliott, Ishola Awokola, Babatunde, Nwankwo, Ogonna N.O., Olufunlola, Adefuye Bolanle, Olumide, Segaolu, Ukwaja, Kingsley N., Irfan, Muhammad, Minarowski, Lukasz, Szymon, Skoczyński, Froes, Felipe, Leuschner, Pedro, Meireles, Mariana, Ferrão, Cláudia, Neves, João, Ravara, Sofia B., Brocovschii, Victoria, Ion, Chesov, Rusu, Doina, Toma, Cristina, Chirita, Daniela, Dorobat, Carmen Mihaela, Birkun, Alexei, Kaluzhenina, Anna, Almotairi, Abdullah, Bukhary, Zakeya Abdulbaqi Ali, Edathodu, Jameela, Fathy, Amal, Mushira Abdulaziz Enani, Abdullah, Eltayeb Mohamed, Nazik, Ulhadi Memon, Jawed, Bella, Abdelhaleem, Bogdanović, Nada, Milenkovic, Branislava, Pesut, Dragica, Borderìas, Luis, Bordon Garcia, Noel Manuel, Cabello Alarcón, Hugo, Cilloniz, Catia, Torres, Antoni, Diaz-Brito, Vicens, Casas, Xavier, Encabo González, Alicia, Fernández-Almira, Maria Luisa, Gallego, Miguel, Gaspar-GarcÍa, Inmaculada, González Del Castillo, Juan, Javaloyes Victoria, Patricia, Laserna Martínez, Elena, Malo de Molina, Rosa, Menéndez, Rosario, Pando-Sandoval, Ana, Prat Aymerich, Cristina, Lacoma de la Torre, Alicia, García-Olivé, Ignasi, Rello, Jordi, Moyano, Silvia, Sanz, Francisco, Sibila, Oriol, Rodrigo-Troyano, Ana, Solé-Violán, Jordi, Uranga, Ane, van Boven, Job F.M., Vendrell Torra, Ester, Pujol, Jordi Almirall, Feldman, Charles, Kee Yum, Ho, Fiogbe, Arnauld Attannon, Yangui, Ferdaous, Bilaceroglu, Semra, Dalar, Levent, Yilmaz, Ufuk, Bogomolov, Artemii, Elahi, Naheed, Dhasmana, Devesh J., Feneley, Andrew, Hancock, Carole, Hill, Adam T., Rudran, Banu, Ruiz-Buitrago, Silvia, Campbell, Marion, Whitaker, Paul, Youzguin, Alexander, Singanayagam, Anika, Allen, Karen S., Brito, Veronica, Dietz, Jessica, Dysart, Claire E., Kellie, Susan M., Franco-Sadud, Ricardo A., Meier, Garnet, Gaga, Mina, Holland, Thomas L., Bergin, Stephen P., Kheir, Fayez, Landmeier, Mark, Lois, Manuel, Nair, Girish B., Patel, Hemali, Reyes, Katherine, Rodriguez-Cintron, William, Saito, Shigeki, Soni, Nilam J., Noda, Julio, Hinojosa, Cecilia I., Levine, Stephanie M., Angel, Luis F., Anzueto, Antonio, Scott Whitlow, K., Hipskind, John, Sukhija, Kunal, Totten, Vicken, Wunderink, Richard G., Shah, Ray D., Mateyo, Kondwelani John, Carugati, Manuela, Morosi, Manuela, Monge, Elisa, Radovanovic, Dejan, Sotgiu, Giovanni, Jankovic, Mateja, Mahesh, Padukudru Anand, Marcos, Pedro Jorge, Abdalla, Mohamed I., Di Pasquale, Marta Francesca, Gramegna, Andrea, Terraneo, Silvia, Blasi, Francesco, Santus, Pierachille, Aliberti, Stefano, Reyes, Luis F., and Restrepo, Marcos I.
- Published
- 2019
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16. Imaging of stress-related disorders
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Kaur, Navneet, additional, Hinojosa, Cecilia, additional, Russell, Julia, additional, VanElzakker, Michael B., additional, and Shin, Lisa M., additional
- Published
- 2020
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17. Reward neurocircuitry predicts longitudinal changes in alcohol use following trauma exposure
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Hinojosa, Cecilia, primary, van Rooij, Sanne J.H., additional, Fani, Negar, additional, Ellis, Robyn A., additional, Harnett, Nathaniel G., additional, Lebois, Lauren, additional, Ely, Timothy D, additional, Jovanovic, Tanja, additional, Murty, Vishnu P., additional, House, Stacey L., additional, Beaudoin, Francesca, additional, An, Xinming, additional, Neylan, Thomas C., additional, Clifford, Gari D, additional, Linnstaedt, Sarah D., additional, Germine, Laura T., additional, Rauch, Scott L., additional, Haran, John P., additional, Storrow, Alan B., additional, Lewandowski, Christopher, additional, Musey, Paul I., additional, Hendry, Phyllis L., additional, Sheikh, Sophia, additional, Jones, Christopher W., additional, Punches, Brittany E., additional, Hudak, Lauren A., additional, Pascual, Jose L., additional, Seamon, Mark S., additional, Harris, Erica, additional, Pearson, Claire, additional, Peak, David A., additional, Merchant, Roland C., additional, Domeier, Robert M., additional, Rathlev, Niels K., additional, O'Neil, Brian J., additional, Sergot, Paulina, additional, Bruce, Steven E., additional, Pizzagalli, Diego A., additional, Sheridan, John F., additional, Harte, Steven E., additional, Koenen, Karestan C., additional, Kessler, Ronald C, additional, McLean, Samuel A., additional, Ressler, Kerry J., additional, and Stevens, Jennifer, additional
- Published
- 2023
- Full Text
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18. Indirect effect of negative evaluations of therapy on the association between racial stress and posttraumatic stress disorder symptoms in pregnant Black persons.
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Ravi, Meghna, primary, Lathan, Emma C., additional, Wallace, Shimarith, additional, Hinojosa, Cecilia A., additional, Jones, Dominique, additional, Villalobos, Jamie, additional, Karra, Sriya, additional, Powers, Abigail, additional, and Michopoulos, Vasiliki, additional
- Published
- 2023
- Full Text
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19. Transcriptional organization of pneumococcal psrP-secY2A2 and impact of GtfA and GtfB deletion on PsrP-associated virulence properties
- Author
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Lizcano, Anel, Akula Suresh Babu, Ramya, Shenoy, Anukul T., Saville, Alison Maren, Kumar, Nikhil, D'Mello, Adonis, Hinojosa, Cecilia A., Gilley, Ryan P., Segovia, Jesus, Mitchell, Timothy J., Tettelin, Hervé, and Orihuela, Carlos J.
- Published
- 2017
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20. Indirect Effect of Negative Evaluations of Therapy on the Association Between Racial Stress and Posttraumatic Stress Disorder Symptoms in Pregnant Black Persons.
- Author
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Ravi, Meghna, Lathan, Emma C., Wallace, Shimarith, Hinojosa, Cecilia A., Jones, Dominique, Villalobos, Jamie, Karra, Sriya, Powers, Abigail, and Michopoulos, Vasiliki
- Published
- 2024
- Full Text
- View/download PDF
21. Targeting the anterior cingulate with bipolar and high-definition transcranial direct current stimulation
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Kaur, Navneet, Whitman, Ethan T., Moser, Amelia D., Hinojosa, Cecilia A., VanElzakker, Michael B., Camprodon, Joan A., Brunyé, Tad T., and Shin, Lisa M.
- Published
- 2020
- Full Text
- View/download PDF
22. Neural Domains Associated with Substance Use Disorders: A Systematic Review of Neuroimaging Studies
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Hinojosa, Cecilia A., primary, Sitar, Siara I., additional, Zhao, Joshua C., additional, Barbosa, Joshua D., additional, Hien, Denise A., additional, Welsh, Justine W., additional, Fani, Negar, additional, and van Rooij, Sanne J.H., additional
- Published
- 2023
- Full Text
- View/download PDF
23. Indirect effect of race‐related stress on traumatic stress and depression symptoms via subjective social status in a Black community sample
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Obenauf, Caterina, primary, Mekawi, Yara, additional, Lathan, Emma C., additional, Hinojosa, Cecilia A., additional, Thomas, Joel G., additional, Stevens, Jennifer S., additional, Powers, Abigail, additional, Michopoulos, Vasiliki, additional, and Carter, Sierra, additional
- Published
- 2023
- Full Text
- View/download PDF
24. Global initiative for meticillin-resistant Staphylococcus aureus pneumonia (GLIMP): an international, observational cohort study
- Author
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Aruj, Patricia Karina, Attorri, Silvia, Barimboim, Enrique, Caeiro, Juan Pablo, Garzón, María I, Cambursano, Victor Hugo, Ceccato, Adrian, Chertcoff, Julio, Lascar, Florencia, Di Tulio, Fernando, Cordon Díaz, Ariel, de Vedia, Lautaro, Ganaha, Maria Cristina, Lambert, Sandra, Lopardo, Gustavo, Luna, Carlos M, Malberti, Alessio Gerardo, Morcillo, Nora, Tartara, Silvina, Pensotti, Claudia, Pereyra, Betiana, Scapellato, Pablo Gustavo, Stagnaro, Juan Pablo, Shah, Sonali, Lötsch, Felix, Thalhammer, Florian, Vincent, Jean Louis, Anseeuw, Kurt, Francois, Camille A, Van Braeckel, Eva, Djimon, Marcel Zannou, Bashi, Jules, Dodo, Roger, Aranha Nouér, Simone, Chipev, Peter, Encheva, Milena, Miteva, Darina, Petkova, Diana, Balkissou, Adamou Dodo, Pefura Yone, Eric Walter, Mbatchou Ngahane, Bertrand Hugo, Shen, Ning, Xu, Jin-fu, Bustamante Rico, Carlos Andres, Buitrago, Ricardo, Pereira Paternina, Fernando Jose, Kayembe Ntumba, Jean-Marie, Vladic Carevic, Vesna, Jakopovic, Marko, Jankovic, Mateja, Matkovic, Zinka, Mitrecic, Ivan, Bouchy Jacobsson, Marie-Laure, Bro Christensen, Anette, Heitmann Bødtger, Uffe Christian, Meyer, Christian Niels, Vestergaard Jensen, Andreas, Baunbæk-knudsen, Gertrud, Trier Petersen, Pelle, Andersen, Stine, El-Said Abd El-Wahhab, Ibrahim, Elsayed Morsy, Nesreen, Shafiek, Hanaa, Sobh, Eman, Abdulsemed, Kedir Abdella, Bertrand, Fabrice, Brun-Buisson, Christian, de Montmollin, Etienne, Fartoukh, Muriel, Messika, Jonathan, Tattevin, Pierre, Khoury, Abdo, Ebruke, Bernard, Dreher, Michael, Kolditz, Martin, Meisinger, Matthias, Pletz, Mathias W, Hagel, Stefan, Rupp, Jan, Schaberg, Tom, Spielmanns, Marc, Creutz, Petra, Suttorp, Norton, Siaw-Lartey, Beatrice, Dimakou, Katerina, Papapetrou, Dimosthenis, Tsigou, Evdoxia, Ampazis, Dimitrios, Kaimakamis, Evangelos, Bhatia, Mohit, Dhar, Raja, D'Souza, George, Garg, Rajiv, Koul, Parvaiz A, Mahesh, P A, Jayaraj, B S, Narayan, Kiran Vishnu, Udnur, Hirennappa B, Krishnamurthy, Shashi Bhaskara, Kant, Surya, Swarnakar, Rajesh, Limaye, Sneha, Salvi, Sundeep, Golshani, Keihan, Keatings, Vera M, Martin-Loeches, Ignacio, Maor, Yasmin, Strahilevitz, Jacob, Battaglia, Salvatore, Carrabba, Maria, Ceriana, Piero, Confalonieri, Marco, d'Arminio Monforte, Antonella, Del Prato, Bruno, De Rosa, Marino, Fantini, Riccardo, Fiorentino, Giuseppe, Gammino, Maria Antonia, Menzella, Francesco, Milani, Giuseppe, Nava, Stefano, Palmiero, Gerardo, Petrino, Roberta, Gabrielli, Barbra, Rossi, Paolo, Sorino, Claudio, Steinhilber, Gundi, Zanforlin, Alessandro, Franzetti, Fabio, Carugati, Manuela, Morosi, Manuela, Monge, Elisa, Carone, Mauro, Patella, Vincenzo, Scarlata, Simone, Comel, Andrea, Kurahashi, Kiyoyasu, Aoun Bacha, Zeina, Barajas Ugalde, Daniel, Ceballos Zuñiga, Omar, Villegas, José F, Medenica, Milic, van de Garde, E M W, Raj Mihsra, Deebya, Shrestha, Poojan, Ridgeon, Elliott, Ishola Awokola, Babatunde, Nwankwo, Ogonna N O, Olufunlola, Adefuye Bolanle, Olumide, Segaolu, Ukwaja, Kingsley N, Irfan, Muhammad, Minarowski, Lukasz, Szymon, Skoczynski, Froes, Felipe, Leuschner, Pedro, Meireles, Mariana, Ferrão, Cláudia, Neves, João, Ravara, Sofia B, Brocovschii, Victoria, Ion, Chesov, Rusu, Doina, Toma, Cristina, Chirita, Daniela, Dorobat, Carmen Mihaela, Birkun, Alexei, Kaluzhenina, Anna, Almotairi, Abdullah, Bukhary, Zakeya Abdulbaqi Ali, Edathodu, Jameela, Fathy, Amal, Mushira Abdulaziz Enani, Abdullah, Eltayeb Mohamed, Nazik, Ulhadi Memon, Jawed, Bella, Abdelhaleem, Bogdanovic, Nada, Milenkovic, Branislava, Pesut, Dragica, Borderìas, Luis, Bordon Garcia, Noel Manuel, Cabello Alarcón, Hugo, Cilloniz, Catia, Torres, Antoni, Diaz-Brito, Vicens, Casas, Xavier, Encabo González, Alicia, Fernández-Almira, Maria Luisa, Gallego, Miguel, Gaspar-GarcÍa, Inmaculada, González del Castillo, Juan, Javaloyes Victoria, Patricia, Laserna Martínez, Elena, Malo de Molina, Rosa, Marcos, Pedro J, Menéndez, Rosario, Pando-Sandoval, Ana, Prat Aymerich, Cristina, Lacoma de la Torre, Alicia, García-Olivé, Ignasi, Rello, Jordi, Moyano, Silvia, Sanz, Francisco, Sibila, Oriol, Rodrigo-Troyano, Ana, Solé-Violán, Jordi, Uranga, Ane, van Boven, Job FM, Vendrell Torra, Ester, Pujol, Jordi Almirall, Feldman, Charles, Kee Yum, Ho, Fiogbe, Arnauld Attannon, Yangui, Ferdaous, Bilaceroglu, Semra, Dalar, Levent, Yilmaz, Ufuk, Bogomolov, Artemii, Elahi, Naheed, Dhasmana, Devesh J, Feneley, Andrew, Ions, Rhiannon, Skeemer, Julie, Woltmann, Gerrit, Hancock, Carole, Hill, Adam T, Rudran, Banu, Ruiz-Buitrago, Silvia, Campbell, Marion, Whitaker, Paul, Youzguin, Alexander, Singanayagam, Anika, Allen, Karen S, Brito, Veronica, Dietz, Jessica, Dysart, Claire E, Kellie, Susan M, Franco-Sadud, Ricardo A, Meier, Garnet, Gaga, Mina, Holland, Thomas L, Bergin, Stephen P, Kheir, Fayez, Landmeier, Mark, Lois, Manuel, Nair, Girish B, Patel, Hemali, Reyes, Katherine, Rodriguez-Cintron, William, Saito, Shigeki, Soni, Nilam J, Noda, Julio, Hinojosa, Cecilia I, Levine, Stephanie M, Angel, Luis F, Anzueto, Antonio, Whitlow, K Scott, Hipskind, John, Sukhija, Kunal, Totten, Vicken, Wunderink, Richard G, Shah, Ray D, Mateyo, Kondwelani John, Noriega, Lorena, Alvarado, Ezequiel, Aman, Mohamed, Labra, Lucía, Aliberti, Stefano, Reyes, Luis F, Faverio, Paola, Sotgiu, Giovanni, Dore, Simone, Rodriguez, Alejandro H, and Restrepo, Marcos I
- Published
- 2016
- Full Text
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25. Endothelial adhesion molecules and multiple organ failure in patients with severe sepsis
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Amalakuhan, Bravein, Habib, Sheila A., Mangat, Mandeep, Reyes, Luis F., Rodriguez, Alejandro H., Hinojosa, Cecilia A., Soni, Nilam J., Gilley, Ryan P., Bustamante, Carlos A., Anzueto, Antonio, Levine, Stephanie M., Peters, Jay I., Aliberti, Stefano, Sibila, Oriol, Chalmers, James D., Torres, Antoni, Waterer, Grant W., Martin-Loeches, Ignacio, Bordon, Jose, Blanquer, Jose, Sanz, Francisco, Marcos, Pedro J., Rello, Jordi, Ramirez, Julio, Solé-Violán, Jordi, Luna, Carlos M., Feldman, Charles, Witzenrath, Martin, Wunderink, Richard G., Stolz, Daiana, Wiemken, Tim L., Shindo, Yuichiro, Dela Cruz, Charles S., Orihuela, Carlos J., and Restrepo, Marcos I.
- Published
- 2016
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26. Cingulate subregions in posttraumatic stress disorder, chronic stress, and treatment
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Hinojosa, Cecilia A., primary, Kaur, Navneet, additional, VanElzakker, Michael B., additional, and Shin, Lisa M., additional
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- 2019
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27. Associations of alcohol and cannabis use with change in posttraumatic stress disorder and depression symptoms over time in recently trauma-exposed individuals.
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Hinojosa, Cecilia A., Liew, Amanda, An, Xinming, Stevens, Jennifer S., Basu, Archana, van Rooij, Sanne J. H., House, Stacey L., Beaudoin, Francesca L., Zeng, Donglin, Neylan, Thomas C., Clifford, Gari D., Jovanovic, Tanja, Linnstaedt, Sarah D., Germine, Laura T., Rauch, Scott L., Haran, John P., Storrow, Alan B., Lewandowski, Christopher, Musey, Paul I., and Hendry, Phyllis L.
- Subjects
- *
POST-traumatic stress disorder , *WOUNDS & injuries , *SELF-evaluation , *REPEATED measures design , *RESEARCH funding , *STRUCTURAL equation modeling , *ANALYSIS of variance , *ALCOHOL drinking , *CANNABIS (Genus) , *COMPARATIVE studies , *MENTAL depression - Abstract
Background: Several hypotheses may explain the association between substance use, posttraumatic stress disorder (PTSD), and depression. However, few studies have utilized a large multisite dataset to understand this complex relationship. Our study assessed the relationship between alcohol and cannabis use trajectories and PTSD and depression symptoms across 3 months in recently trauma-exposed civilians. Methods: In total, 1618 (1037 female) participants provided self-report data on past 30-day alcohol and cannabis use and PTSD and depression symptoms during their emergency department (baseline) visit. We reassessed participant's substance use and clinical symptoms 2, 8, and 12 weeks posttrauma. Latent class mixture modeling determined alcohol and cannabis use trajectories in the sample. Changes in PTSD and depression symptoms were assessed across alcohol and cannabis use trajectories via a mixed-model repeated-measures analysis of variance. Results: Three trajectory classes (low, high, increasing use) provided the best model fit for alcohol and cannabis use. The low alcohol use class exhibited lower PTSD symptoms at baseline than the high use class; the low cannabis use class exhibited lower PTSD and depression symptoms at baseline than the high and increasing use classes; these symptoms greatly increased at week 8 and declined at week 12. Participants who already use alcohol and cannabis exhibited greater PTSD and depression symptoms at baseline that increased at week 8 with a decrease in symptoms at week 12. Conclusions: Our findings suggest that alcohol and cannabis use trajectories are associated with the intensity of posttrauma psychopathology. These findings could potentially inform the timing of therapeutic strategies. [ABSTRACT FROM AUTHOR]
- Published
- 2024
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28. A marmoset model for Mycobacterium avium complex pulmonary disease
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Peters, Jay, primary, Maselli, Diego Jose, additional, Mangat, Mandeep, additional, Coalson, Jacqueline J., additional, Hinojosa, Cecilia, additional, Giavedoni, Luis, additional, Brown-Elliott, Barbara A., additional, Chan, Edward, additional, and Griffith, David, additional
- Published
- 2023
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29. Individualizing TMS treatment targets for PTSD using neuroimaging: Preliminary findings from an ongoing clinical trial
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van Rooij, Sanne, primary, Teye-Botchway, Lois, additional, Hinojosa, Cecilia, additional, Minton, Sean, additional, Job, Gregory, additional, Riva-Posse, Patricio, additional, Rauch, Sheila, additional, Ressler, Kerry, additional, Jovanovic, Tanja, additional, Holtzheimer, Paul, additional, Calhoun, Vince, additional, Camprodon, Joan, additional, and McDonald, William, additional
- Published
- 2023
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- View/download PDF
30. Both nicotine reward and withdrawal are enhanced in a rodent model of diabetes
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Pipkin, Joseph A., Cruz, Bryan, Flores, Rodolfo J., Hinojosa, Cecilia A., Carcoba, Luis M., Ibarra, Melissa, Francis, Wendy, Nazarian, Arbi, and O’Dell, Laura E.
- Published
- 2017
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31. It’s Not All in Your Head: Discrimination and Its Association With the Brain-Gut Axis
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Stevens, Jennifer S. and Hinojosa, Cecilia A.
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- 2023
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32. Alcohol self-administration and nicotine withdrawal alter biomarkers of stress and inflammation and prefrontal cortex changes in Gβ subunits
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Cruz, Bryan, primary, Castañeda, Karen, additional, Aranda, Michelle, additional, Hinojosa, Cecilia A., additional, Castro-Gutierrez, Roberto, additional, Flores, Rodolfo J., additional, Spencer, Charles T., additional, Vozella, Valentina, additional, Roberto, Marisa, additional, Gadad, Bharathi S., additional, Roychowdhury, Sukla, additional, and O’Dell, Laura E., additional
- Published
- 2022
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33. Severe Pneumococcal Pneumonia Causes Acute Cardiac Toxicity and Subsequent Cardiac Remodeling
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Reyes, Luis F., Restrepo, Marcos I., Hinojosa, Cecilia A., Soni, Nilam J., Anzueto, Antonio, Babu, Bettina L., Gonzalez-Juarbe, Norberto, Rodriguez, Alejandro H., Jimenez, Alejandro, Chalmers, James D., Aliberti, Stefano, Sibila, Oriol, Winter, Vicki T., Coalson, Jacqueline J., Giavedoni, Luis D., Dela Cruz, Charles S., Waterer, Grant W., Witzenrath, Martin, Suttorp, Norbert, Dube, Peter H., and Orihuela, Carlos J.
- Published
- 2017
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34. Pre-treatment amygdala activation and habituation predict symptom change in post-traumatic stress disorder.
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Hinojosa, Cecilia A., VanElzakker, Michael B., Kaur, Navneet, Felicione, Julia M., Charney, Meredith E., Bui, Eric, Marques, Luana, Summergrad, Paul, Rauch, Scott L., Simon, Naomi M., and Shin, Lisa M.
- Subjects
AMYGDALOID body ,POST-traumatic stress disorder ,HABITUATION (Neuropsychology) ,FUNCTIONAL magnetic resonance imaging ,FACIAL expression ,EXPOSURE therapy - Abstract
Trauma-focused psychotherapy approaches are the first-line treatment option for post-traumatic stress disorder (PTSD); however, up to a third of patients remain symptomatic even after completion of the treatment. Predicting which patients will respond to a given treatment option would support personalized treatments and improve the e_ciency of healthcare systems. Although previous neuroimaging studies have examined possible pre-treatment predictors of response to treatment, the findings have been somewhat inconsistent, and no other study has examined habituation to stimuli as a predictor. In this study, 16 treatment-seeking adults (M
Age = 43.63, n = 10 women) with a primary diagnosis of PTSD passively viewed pictures of emotional facial expressions during functional magnetic resonance imaging (fMRI). After scanning, participants rated facial expressions on both valence and arousal. Participants then completed eight weekly sessions of prolonged exposure (PE) therapy. PTSD symptom severity was measured before and after treatment. Overall, participants showed symptomatic improvement with PE. Consistent with hypotheses, lesser activation in the amygdala and greater activation in the ventromedial prefrontal cortex during the presentation of fearful vs. happy facial expressions, as well as a greater decline in amygdala activation across blocks of fearful facial expressions at baseline, were associated with greater reduction of PTSD symptoms. Given that the repeated presentation of emotional material underlies PE, changes in brain responses with repeated stimulus presentations warrant further studies as potential predictors of response to exposure therapies. [ABSTRACT FROM AUTHOR]- Published
- 2023
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- View/download PDF
35. P653. Understanding the Co-Emergence of PTSD and Alcohol Use: Exploring Time Since Trauma and the Role of the vmPFC
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Hinojosa, Cecilia, primary, van Rooij, Sanne J.H., additional, Harnett, Nathaniel G., additional, Lebois, Lauren A.M., additional, Murty, Vishnu P., additional, Jovanovic, Tanja, additional, House, Stacey, additional, Fani, Negar, additional, McLean, Samuel A., additional, Ressler, Kerry, additional, and Stevens, Jennifer, additional
- Published
- 2022
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36. Metformin Attenuates Inflammatory Responses and Enhances Antibody Production in an Acute Pneumonia Model of Streptococcus pneumoniae
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Lee, Grace C., primary, Moreira, Alvaro G., additional, Hinojosa, Cecilia, additional, Benavides, Raymond, additional, Winter, Caitlyn, additional, Anderson, Audrey C., additional, Chen, Chang-Jui, additional, Borsa, Noemi, additional, Hastings, Gabrielyd, additional, Black, Cody A., additional, Bandy, Sarah M., additional, Shaffer, Alexander, additional, Restrepo, Marcos I., additional, and Ahuja, Sunil K., additional
- Published
- 2022
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37. Right inferior frontal gyrus and ventromedial prefrontal activation during response inhibition is implicated in the development of PTSD symptoms
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Powers, Abigail, primary, Hinojosa, Cecilia A., additional, Stevens, Jennifer S., additional, Harvey, Brandon, additional, Pas, Pascal, additional, Rothbaum, Barbara O., additional, Ressler, Kerry J., additional, Jovanovic, Tanja, additional, and van Rooij, Sanne J.H., additional
- Published
- 2022
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38. Alcohol self-administration and nicotine withdrawal alter biomarkers of stress and inflammation and prefrontal cortex changes in Gβ subunits.
- Author
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Cruz, Bryan, Castañeda, Karen, Aranda, Michelle, Hinojosa, Cecilia A., Castro-Gutierrez, Roberto, Flores, Rodolfo J., Spencer, Charles T., Vozella, Valentina, Roberto, Marisa, Gadad, Bharathi S., Roychowdhury, Sukla, and O'Dell, Laura E.
- Subjects
PREFRONTAL cortex ,NICOTINE ,G protein coupled receptors ,ALCOHOL ,NUCLEUS accumbens - Abstract
Background: Although alcohol and nicotine are often used together, the biological consequences of these substances are not well understood. Identifying shared targets will inform cessation pharmacotherapies and provide a deeper understanding of how co-use of alcohol and nicotine impacts health, including biomarkers of stress and inflammation. Objective: We examined the effects of nicotine exposure and withdrawal on alcohol self-administration (SA), stress and inflammatory biomarkers, and a G-protein coupled receptor subunit (Gβ) in brain areas associated with drug use. Methods: Male rats were trained to SA alcohol and then received a nicotine pump (n = 7–8 per group). We assessed alcohol intake for 12 days during nicotine exposure and then following pump removal to elicit withdrawal. After the behavioral studies, we assessed plasma leptin, corticosterone, and interleukin-1β (IL-1β), and Gβ protein expression in the amygdala, nucleus accumbens (NAc), and prefrontal cortex (PFC). Results: Nicotine exposure or withdrawal did not alter alcohol intake (p >.05). Alcohol and nicotine withdrawal elevated corticosterone levels (p =.015) and decreased Gβ levels in the PFC (p =.004). In the absence of nicotine, alcohol SA suppressed IL-1β levels (p =.039). Chronic exposure to nicotine or withdrawal during alcohol SA did not alter leptin levels or Gβ expression in the amygdala or NAc (p's >.05). Conclusions: The combination of alcohol SA and nicotine withdrawal produced a persistent increase in stress biomarkers and a suppression in Gβ expression in the PFC, providing an important first step toward understanding the common biological mechanisms of alcohol/nicotine misuse. [ABSTRACT FROM AUTHOR]
- Published
- 2023
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39. Prevalence and Etiology of Community-acquired Pneumonia in Immunocompromised Patients
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Di Pasquale, Marta Francesca, Sotgiu, Giovanni, Gramegna, Andrea, Radovanovic, Dejan, Terraneo, Silvia, Reyes, Luis F, Rupp, Jan, González del Castillo, Juan, Blasi, Francesco, Aliberti, Stefano, Restrepo, Marcos I, Aruj, Patricia Karina, Attorri, Silvia, Barimboim, Enrique, Caeiro, Juan Pablo, Garzón, María I, Cambursano, Victor Hugo, Cazaux, A, Ceccato, Adrian, Chertcoff, Julio, Lascar, Florencia, Tulio, Fernando Di, Díaz, Ariel Cordon, de Vedia, Lautaro, Ganaha, Maria Cristina, Lambert, Sandra, Lopardo, Gustavo, Luna, Carlos M, Malberti, Alessio Gerardo, Morcillo, Nora, Tartara, Silvina, Cetrangolo, Antonio A, Pensotti, Claudia, Pereyra, Betiana, Scapellato, Pablo Gustavo, Stagnaro, Juan Pablo, Shah, Sonali, Lötsch, Felix, Thalhammer, Florian, Anseeuw, Kurt, Francois, Camille A, Van Braeckel, Eva, Vincent, Jean Louis, Djimon, Marcel Zannou, Bashi, Jules, Dodo, Roger, Nouér, Simone Aranha, Chipev, Peter, Encheva, Milena, Miteva, Darina, Petkova, Diana, Balkissou, Adamou Dodo, Yone, Eric Walter Pefura, Ngahane, Bertrand Hugo Mbatchou, Shen, Ning, Xu, Jin-fu, Rico, Carlos Andres Bustamante, Buitrago, Ricardo, Paternina, Fernando Jose Pereira, Ntumba, Jean-Marie Kayembe, Carevic, Vesna Vladic, Jakopovic, Marko, Jankovic, Mateja, Matkovic, Zinka, Mitrecic, Ivan, Jacobsson, Marie-Laure Bouchy, Christensen, Anette Bro, Bødtger, Uffe Christian Heitmann, Meyer, Christian Niels, Jensen, Andreas Vestergaard, Baunbæk-Knudsen, Gertrud, Petersen, Pelle Trier, Andersen, Stine, El-Wahhab, Ibrahim El-Said Abd, Morsy, Nesreen Elsayed, Shafiek, Hanaa, Sobh, Eman, Abdulsemed, Kedir Abdella, Bertrand, Fabrice, Brun-Buisson, Christian, de Montmollin, Etienne, Fartoukh, Muriel, Messika, Jonathan, Tattevin, Pierre, Khoury, Abdo, Ebruke, Bernard, Dreher, Michael, Kolditz, Martin, Meisinger, Matthias, Niederlausitz, Klinikum, Pletz, Mathias W, Hagel, Stefan, Schaberg, Tom, Spielmanns, Marc, Creutz, Petra, Suttorp, Norton, Siaw-Lartey, Beatrice, Dimakou, Katerina, Papapetrou, Dimosthenis, Tsigou, Evdoxia, Ampazis, Dimitrios, Kaimakamis, Evangelos, Bhatia, Mohit, Dhar, Raja, D’Souza, George, Garg, Rajiv, Koul, Parvaiz A, Mahesh, P A, Jayaraj, B S, Narayan, Kiran Vishnu, Udnur, Hirennappa B, Krishnamurthy, Shashi Bhaskara, Kant, Surya, Swarnakar, Rajesh, Limaye, Sneha, Salvi, Sundeep, Golshani, Keihan, Keatings, Vera M, Martin-Loeches, Ignacio, Maor, Yasmin, Strahilevitz, Jacob, Battaglia, Salvatore, Carrabba, Maria, Ceriana, Piero, Confalonieri, Marco, Monforte, Antonella d’Arminio, Prato, Bruno Del, Rosa, Marino De, Fantini, Riccardo, Fiorentino, Giuseppe, Gammino, Maria Antonia, Menzella, Francesco, Milani, Giuseppe, Nava, Stefano, Palmiero, Gerardo, Petrino, Roberta, Gabrielli, Barbra, Rossi, Paolo, Sorino, Claudio, Steinhilber, Gundi, Zanforlin, Alessandro, Franzetti, Fabio, Carugati, Manuela, Morosi, Manuela, Monge, Elisa, Carone, Mauro, Patella, Vincenzo, Scarlata, Simone, Comel, Andrea, Kurahashi, Kiyoyasu, Bacha, Zeina Aoun, Ugalde, Daniel Barajas, Zuñiga, Omar Ceballos, Villegas, José F, Medenica, Milic, van de Garde, E M W, Mihsra, Deebya Raj, Shrestha, Poojan, Ridgeon, Elliott, Awokola, Babatunde Ishola, Nwankwo, Ogonna N O, Olufunlola, Adefuye Bolanle, Olumide, Segaolu, Ukwaja, Kingsley N, Irfan, Muhammad, Minarowski, Lukasz, Szymon, Skoczyński, Froes, Felipe, Leuschner, Pedro, Meireles, Mariana, Ferrão, Cláudia, Neves, João, Ravara, Sofia B, Brocovschii, Victoria, Ion, Chesov, Rusu, Doina, Toma, Cristina, Chirita, Daniela, Dorobat, Carmen Mihaela, Birkun, Alexei, Kaluzhenina, Anna, Almotairi, Abdullah, Bukhary, Zakeya Abdulbaqi Ali, Edathodu, Jameela, Fathy, Amal, Enani, Abdullah Mushira Abdulaziz, Mohamed, Nazik Eltayeb, Memon, Jawed Ulhadi, Bella, Abdelhaleem, Bogdanović, Nada, Milenkovic, Branislava, Pesut, Dragica, Borderìas, Luis, Garcia, Noel Manuel Bordon, Alarcón, Hugo Cabello, Cilloniz, Catia, Torres, Antoni, Diaz-Brito, Vicens, Casas, Xavier, González, Alicia Encabo, Fernández-Almira, Maria Luisa, Gallego, Miguel, Gaspar-GarcÍa, Inmaculada, del Castillo, Juan González, Victoria, Patricia Javaloyes, Martínez, Elena Laserna, de Molina, Rosa Malo, Marcos, Pedro J, Menéndez, Rosario, Pando-Sandoval, Ana, Aymerich, Cristina Prat, de la Torre, Alicia Lacoma, García-Olivé, Ignasi, Rello, Jordi, Moyano, Silvia, Sanz, Francisco, Sibila, Oriol, Rodrigo-Troyano, Ana, Solé-Violán, Jordi, Uranga, Ane, van Boven, Job F M, Torra, Ester Vendrell, Pujol, Jordi Almirall, Feldman, Charles, Yum, Ho Kee, Fiogbe, Arnauld Attannon, Yangui, Ferdaous, Bilaceroglu, Semra, Dalar, Levent, Yilmaz, Ufuk, Bogomolov, Artemii, Elahi, Naheed, Dhasmana, Devesh J, Feneley, Andrew, Ions, Rhiannon, Skeemer, Julie, Woltmann, Gerrit, Hancock, Carole, Hill, Adam T, Rudran, Banu, Ruiz-Buitrago, Silvia, Campbell, Marion, Whitaker, Paul, Youzguin, Alexander, Singanayagam, Anika, Allen, Karen S, Brito, Veronica, Dietz, Jessica, Dysart, Claire E, Kellie, Susan M, Franco-Sadud, Ricardo A, Meier, Garnet, Gaga, Mina, Holland, Thomas L, Bergin, Stephen P, Kheir, Fayez, Landmeier, Mark, Lois, Manuel, Nair, Girish B, Patel, Hemali, Reyes, Katherine, Rodriguez-Cintron, William, Saito, Shigeki, Soni, Nilam J, Noda, Julio, Hinojosa, Cecilia I, Levine, Stephanie M, Angel, Luis F, Anzueto, Antonio, Whitlow, K Scott, Hipskind, John, Sukhija, Kunal, Totten, Vicken, Wunderink, Richard G, Shah, Ray D, Mateyo, Kondwelani John, Noriega, Lorena, Alvarado, Ezequiel, Aman, Mohamed, Labra, Lucía, Value, Affordability and Sustainability (VALUE), Groningen Research Institute for Asthma and COPD (GRIAC), Di Pasquale, M. F., Sotgiu, G., Gramegna, A., Radovanovic, D., Terraneo, S., Reyes, L. F., Rupp, J., Gonzalez Del Castillo, J., Blasi, F., Aliberti, S., Restrepo, M. I., Aruj, P. K., Attorri, S., Barimboim, E., Caeiro, J. P., Garzon, M. I., Cambursano, V. H., Cazaux, A., Ceccato, A., Chertcoff, J., Lascar, F., Tulio, F. D., Diaz, A. C., de Vedia, L., Ganaha, M. C., Lambert, S., Lopardo, G., Luna, C. M., Malberti, A. G., Morcillo, N., Tartara, S., Cetrangolo, A. A., Pensotti, C., Pereyra, B., Scapellato, P. G., Stagnaro, J. P., Shah, S., Lotsch, F., Thalhammer, F., Anseeuw, K., Francois, C. A., Van Braeckel, E., Vincent, J. L., Djimon, M. Z., Bashi, J., Dodo, R., Nouer, S. A., Chipev, P., Encheva, M., Miteva, D., Petkova, D., Balkissou, A. D., Yone, E. W. P., Ngahane, B. H. M., Shen, N., Xu, J. F., Rico, C. A. B., Buitrago, R., Paternina, F. J. P., Ntumba, J. K., Carevic, V. V., Jakopovic, M., Jankovic, M., Matkovic, Z., Mitrecic, I., Jacobsson, M. B., Christensen, A. B., Bodtger, U. C. H., Meyer, C. N., Jensen, A. V., Baunbaek-Knudsen, G., Petersen, P. T., Andersen, S., El-Wahhab, I. E. A., Morsy, N. E., Shafiek, H., Sobh, E., Abdulsemed, K. A., Bertrand, F., Brun-Buisson, C., de Montmollin, E., Fartoukh, M., Messika, J., Tattevin, P., Khoury, A., Ebruke, B., Dreher, M., Kolditz, M., Meisinger, M., Niederlausitz, K., Pletz, M. W., Hagel, S., Schaberg, T., Spielmanns, M., Creutz, P., Suttorp, N., Siaw-Lartey, B., Dimakou, K., Papapetrou, D., Tsigou, E., Ampazis, D., Kaimakamis, E., Bhatia, M., Dhar, R., D'Souza, G., Garg, R., Koul, P. A., Mahesh, P. A., Jayaraj, B. S., Narayan, K. V., Udnur, H. B., Krishnamurthy, S. B., Kant, S., Swarnakar, R., Limaye, S., Salvi, S., Golshani, K., Keatings, V. M., Martin-Loeches, I., Maor, Y., Strahilevitz, J., Battaglia, S., Carrabba, M., Ceriana, P., Confalonieri, M., Monforte, A. D., Prato, B. D., Rosa, M., Fantini, R., Fiorentino, G., Gammino, M. A., Menzella, F., Milani, G., Nava, S., Palmiero, G., Petrino, R., Gabrielli, B., Rossi, P., Sorino, C., Steinhilber, G., Zanforlin, A., Franzetti, F., Carugati, M., Morosi, M., Monge, E., Carone, M., Patella, V., Scarlata, S., Comel, A., Kurahashi, K., Bacha, Z. A., Ugalde, D. B., Zuniga, O. C., Villegas, J. F., Medenica, M., van de Garde, E. M. W., Mihsra, D. R., Shrestha, P., Ridgeon, E., Awokola, B. I., Nwankwo, O. N. O., Olufunlola, A. B., Olumide, S., Ukwaja, K. N., Irfan, M., Minarowski, L., Szymon, S., Froes, F., Leuschner, P., Meireles, M., Ferrao, C., Neves, J., Ravara, S. B., Brocovschii, V., Ion, C., Rusu, D., Toma, C., Chirita, D., Dorobat, C. M., Birkun, A., Kaluzhenina, A., Almotairi, A., Bukhary, Z. A. A., Edathodu, J., Fathy, A., Enani, A. M. A., Mohamed, N. E., Memon, J. U., Bella, A., Bogdanovic, N., Milenkovic, B., Pesut, D., Borderias, L., Garcia, N. M. B., Alarcon, H. C., Cilloniz, C., Torres, A., Diaz-Brito, V., Casas, X., Gonzalez, A. E., Fernandez-Almira, Ml., Gallego, M., Gaspar-GarcIa, I., Victoria, P. J., Martinez, E. L., de Molina, R. M., Marcos, P. J., Menendez, R., Pando-Sandoval, A., Aymerich, C. P., de la Torre, A. L., Garcia-Olive, I., Rello, J., Moyano, S., Sanz, F., Sibila, O., Rodrigo-Troyano, A., Sole-Violan, J., Uranga, A., van Boven, J. F. M., Torra, E. V., Pujol, J. A., Feldman, C., Yum, H. K., Fiogbe, A. A., Yangui, F., Bilaceroglu, S., Dalar, L., Yilmaz, U., Bogomolov, A., Elahi, N., Dhasmana, D. J., Feneley, A., Ions, R., Skeemer, J., Woltmann, G., Hancock, C., Hill, A. T., Rudran, B., Ruiz-Buitrago, S., Campbell, M., Whitaker, P., Youzguin, A., Singanayagam, A., Allen, K. S., Brito, V., Dietz, J., Dysart, C. E., Kellie, S. M., Franco-Sadud, R. A., Meier, G., Gaga, M., Holland, T. L., Bergin, S. P., Kheir, F., Landmeier, M., Lois, M., Nair, G. B., Patel, H., Reyes, K., Rodriguez-Cintron, W., Saito, S., Soni, N. J., Noda, J., Hinojosa, C. I., Levine, S. M., Angel, L. F., Anzueto, A., Whitlow, K. S., Hipskind, J., Sukhija, K., Totten, V., Wunderink, R. G., Shah, R. D., Mateyo, K. J., Noriega, L., Alvarado, E., Aman, M., Labra, L., Di Pasquale M.F., Sotgiu G., Gramegna A., Radovanovic D., Terraneo S., Reyes L.F., Rupp J., Gonzalez Del Castillo J., Blasi F., Aliberti S., Restrepo M.I., Aruj P.K., Attorri S., Barimboim E., Caeiro J.P., Garzon M.I., Cambursano V.H., Cazaux A., Ceccato A., Chertcoff J., Lascar F., Tulio F.D., Diaz A.C., de Vedia L., Ganaha M.C., Lambert S., Lopardo G., Luna C.M., Malberti A.G., Morcillo N., Tartara S., Cetrangolo A.A., Pensotti C., Pereyra B., Scapellato P.G., Stagnaro J.P., Shah S., Lotsch F., Thalhammer F., Anseeuw K., Francois C.A., Van Braeckel E., Vincent J.L., Djimon M.Z., Bashi J., Dodo R., Nouer S.A., Chipev P., Encheva M., Miteva D., Petkova D., Balkissou A.D., Yone E.W.P., Ngahane B.H.M., Shen N., Xu J.F., Rico C.A.B., Buitrago R., Paternina F.J.P., Ntumba J.K., Carevic V.V., Jakopovic M., Jankovic M., Matkovic Z., Mitrecic I., Jacobsson M.B., Christensen A.B., Bodtger U.C.H., Meyer C.N., Jensen A.V., Baunbaek-Knudsen G., Petersen P.T., Andersen S., El-Wahhab I.E.A., Morsy N.E., Shafiek H., Sobh E., Abdulsemed K.A., Bertrand F., Brun-Buisson C., de Montmollin E., Fartoukh M., Messika J., Tattevin P., Khoury A., Ebruke B., Dreher M., Kolditz M., Meisinger M., Niederlausitz K., Pletz M.W., Hagel S., Schaberg T., Spielmanns M., Creutz P., Suttorp N., Siaw-Lartey B., Dimakou K., Papapetrou D., Tsigou E., Ampazis D., Kaimakamis E., Bhatia M., Dhar R., D'Souza G., Garg R., Koul P.A., Mahesh P.A., Jayaraj B.S., Narayan K.V., Udnur H.B., Krishnamurthy S.B., Kant S., Swarnakar R., Limaye S., Salvi S., Golshani K., Keatings V.M., Martin-Loeches I., Maor Y., Strahilevitz J., Battaglia S., Carrabba M., Ceriana P., Confalonieri M., Monforte A.D., Prato B.D., Rosa M., Fantini R., Fiorentino G., Gammino M.A., Menzella F., Milani G., Nava S., Palmiero G., Petrino R., Gabrielli B., Rossi P., Sorino C., Steinhilber G., Zanforlin A., Franzetti F., Carugati M., Morosi M., Monge E., Carone M., Patella V., Scarlata S., Comel A., Kurahashi K., Bacha Z.A., Ugalde D.B., Zuniga O.C., Villegas J.F., Medenica M., van de Garde E.M.W., Mihsra D.R., Shrestha P., Ridgeon E., Awokola B.I., Nwankwo O.N.O., Olufunlola A.B., Olumide S., Ukwaja K.N., Irfan M., Minarowski L., Szymon S., Froes F., Leuschner P., Meireles M., Ferrao C., Neves J., Ravara S.B., Brocovschii V., Ion C., Rusu D., Toma C., Chirita D., Dorobat C.M., Birkun A., Kaluzhenina A., Almotairi A., Bukhary Z.A.A., Edathodu J., Fathy A., Enani A.M.A., Mohamed N.E., Memon J.U., Bella A., Bogdanovic N., Milenkovic B., Pesut D., Borderias L., Garcia N.M.B., Alarcon H.C., Cilloniz C., Torres A., Diaz-Brito V., Casas X., Gonzalez A.E., Fernandez-Almira ML., Gallego M., Gaspar-GarcIa I., Victoria P.J., Martinez E.L., de Molina R.M., Marcos P.J., Menendez R., Pando-Sandoval A., Aymerich C.P., de la Torre A.L., Garcia-Olive I., Rello J., Moyano S., Sanz F., Sibila O., Rodrigo-Troyano A., Sole-Violan J., Uranga A., van Boven J.F.M., Torra E.V., Pujol J.A., Feldman C., Yum H.K., Fiogbe A.A., Yangui F., Bilaceroglu S., Dalar L., Yilmaz U., Bogomolov A., Elahi N., Dhasmana D.J., Feneley A., Ions R., Skeemer J., Woltmann G., Hancock C., Hill A.T., Rudran B., Ruiz-Buitrago S., Campbell M., Whitaker P., Youzguin A., Singanayagam A., Allen K.S., Brito V., Dietz J., Dysart C.E., Kellie S.M., Franco-Sadud R.A., Meier G., Gaga M., Holland T.L., Bergin S.P., Kheir F., Landmeier M., Lois M., Nair G.B., Patel H., Reyes K., Rodriguez-Cintron W., Saito S., Soni N.J., Noda J., Hinojosa C.I., Levine S.M., Angel L.F., Anzueto A., Whitlow K.S., Hipskind J., Sukhija K., Totten V., Wunderink R.G., Shah R.D., Mateyo K.J., Noriega L., Alvarado E., Aman M., and Labra L.
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0301 basic medicine ,Male ,Pediatrics ,Etiology ,Multidrug-resistant pathogen ,MRSA ,Pneumocystis pneumonia ,Pneumònia adquirida a la comunitat ,HOSPITALIZED-PATIENTS ,0302 clinical medicine ,Community-acquired pneumonia ,Risk Factors ,Prevalence ,Medicine ,030212 general & internal medicine ,PNEUMOCYSTIS PNEUMONIA ,Articles and Commentaries ,Aged, 80 and over ,Respiratory tract infections ,Anemia, Aplastic ,Middle Aged ,3. Good health ,Community-Acquired Infections ,Europe ,Infectious Diseases ,Immunocompromise ,Microbiology ,Multidrug-resistant pathogens ,Pneumonia ,Etiologia ,Hematologic Neoplasms ,Female ,BLOOD-STREAM INFECTIONS ,Lung Transplantation ,Microbiology (medical) ,medicine.medical_specialty ,Asia ,Neutropenia ,030106 microbiology ,RESPIRATORY-TRACT INFECTIONS ,Settore MED/10 - Malattie Dell'Apparato Respiratorio ,TRANSPLANT RECIPIENTS ,DISEASES-SOCIETY ,03 medical and health sciences ,Immunocompromised Host ,Pneumonia, Bacterial ,MANAGEMENT ,Humans ,pneumonia ,BACTERIAL PNEUMONIA ,Aged ,Acquired Immunodeficiency Syndrome ,business.industry ,microbiology ,Bacterial pneumonia ,Australia ,medicine.disease ,multidrug-resistant pathogens ,Mycoses ,Bacteremia ,Africa ,RISK-FACTORS ,immunocompromise ,Americas ,business - Abstract
Background The correct management of immunocompromised patients with pneumonia is debated. We evaluated the prevalence, risk factors, and characteristics of immunocompromised patients coming from the community with pneumonia. Methods We conducted a secondary analysis of an international, multicenter study enrolling adult patients coming from the community with pneumonia and hospitalized in 222 hospitals in 54 countries worldwide. Risk factors for immunocompromise included AIDS, aplastic anemia, asplenia, hematological cancer, chemotherapy, neutropenia, biological drug use, lung transplantation, chronic steroid use, and solid tumor. Results At least 1 risk factor for immunocompromise was recorded in 18% of the 3702 patients enrolled. The prevalences of risk factors significantly differed across continents and countries, with chronic steroid use (45%), hematological cancer (25%), and chemotherapy (22%) the most common. Among immunocompromised patients, community-acquired pneumonia (CAP) pathogens were the most frequently identified, and prevalences did not differ from those in immunocompetent patients. Risk factors for immunocompromise were independently associated with neither Pseudomonas aeruginosa nor non–community-acquired bacteria. Specific risk factors were independently associated with fungal infections (odds ratio for AIDS and hematological cancer, 15.10 and 4.65, respectively; both P = .001), mycobacterial infections (AIDS; P = .006), and viral infections other than influenza (hematological cancer, 5.49; P < .001). Conclusions Our findings could be considered by clinicians in prescribing empiric antibiotic therapy for CAP in immunocompromised patients. Patients with AIDS and hematological cancer admitted with CAP may have higher prevalences of fungi, mycobacteria, and noninfluenza viruses.
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- 2019
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40. A Marmoset Model for Mycobacterium avium Complex Pulmonary Disease
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Peters, Jay, primary, Maselli, Diego Jose, additional, Mangat, Mandeep, additional, Coalson, Jacqueline J., additional, Hinojosa, Cecilia, additional, Giavedoni, Luis, additional, Brown-Elliott, Barbara, additional, Chan, Edward, additional, and Griffith, David, additional
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- 2021
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41. Elevated A20 contributes to age-dependent macrophage dysfunction in the lungs
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Hinojosa, Cecilia A., Akula Suresh Babu, Ramya, Rahman, Md M., Fernandes, Gabriel, Boyd, Angela R., and Orihuela, Carlos J.
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- 2014
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42. Omega-3 fatty acids in contrast to omega-6 protect against pneumococcal pneumonia
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Hinojosa, Cecilia A., Gonzalez-Juarbe, Norberto, Rahman, Md M., Fernandes, Gabriel, Orihuela, Carlos J., and Restrepo, Marcos I.
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- 2020
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43. Enteric-delivered rapamycin enhances resistance of aged mice to pneumococcal pneumonia through reduced cellular senescence
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Hinojosa, Cecilia A., Mgbemena, Victoria, Roekel, Sabrina Van, Austad, Steven N., Miller, Richard A., Bose, Santanu, and Orihuela, Carlos J.
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- 2012
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44. Amygdala Response to Traumatic Childbirth Recall is Associated With Impaired Bonding Behaviors in Mothers With Childbirth-Related PTSD Symptoms: Preliminary Findings
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Berman, Zohar, primary, Kaim, Arielle, additional, Reed, Taylor, additional, Felicione, Julia, additional, Hinojosa, Cecilia, additional, Oliver, Katelyn, additional, Rutherford, Helena, additional, Mayes, Linda, additional, Shin, Lisa, additional, and Dekel, Sharon, additional
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- 2020
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45. Metformin Attenuates Inflammatory Responses and Enhances Antibody Production in an Acute Pneumonia Model of Streptococcus pneumoniae.
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Grace C. Lee, Moreira, Alvaro G., Hinojosa, Cecilia, Benavides, Raymond, Winter, Caitlyn, Anderson, Audrey C., Chang-Jui Chen, Borsa, Noemi, Hastings, Gabrielyd, Black, Cody A., Bandy, Sarah M., Shaffer, Alexander, Restrepo, Marcos I., and Ahuja, Sunil K.
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- 2022
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46. Bacterial etiology of community-acquired pneumonia in immunocompetent hospitalized patients and appropriateness of empirical treatment recommendations: an international point-prevalence study
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Carugati, Manuela, Aliberti, S., Sotgiu, G., Blasi, F., Gori, A., Menendez, R., Encheva, M., Gallego, M., Leuschner, P., Ruiz-Buitrago, S., Battaglia, S., Fantini, R., Pascual-Guardia, S., Marin-Corral, J., Restrepo, M. I., Aruj, Patricia Karina, Attorri, Silvia, Barimboim, Enrique, Caeiro, Juan Pablo, Garzón, María I, Cambursano, Victor Hugo, Ceccato, Adrian, Chertcoff, Julio, Lascar, Florencia, Tulio, Fernando Di, Díaz, Ariel Cordon, de Vedia, Lautaro, Ganaha, Maria Cristina, Lambert, Sandra, Lopardo, Gustavo, Luna, Carlos M, Malberti, Alessio Gerardo, Morcillo, Nora, Tartara, Silvina, Pensotti, Claudia, Pereyra, Betiana, Scapellato, Pablo Gustavo, Stagnaro, Juan Pablo, Shah, Sonali, Lötsch, Felix, Thalhammer, Florian, Vincent, Jean Louis, Anseeuw, Kurt, Francois, Camille A, Van Braeckel, Eva, Djimon, Marcel Zannou, Bashi, Jules, Roger, Dodo, Nouér, Simone Aranha, Chipev, Peter, Encheva, Milena, Miteva, Darina, Petkova, Diana, Dodo, Balkissou Adamou, Ngahane, Mbatchou, Hugo, Bertrand, Shen, Ning, Xu, Jin-fu, Rico, Carlos Andres Bustamante, Buitrago, Ricardo, Paternina, Fernando Jose Pereira, Jean-Marie, Kayembe Ntumba, Carevic, Vesna Vladic, Jakopovic, Marko, Jankovic, Mateja, Matkovic, Zinka, Mitrecic, Ivan, Jacobsson, Marie-Laure Bouchy, Christensen, Anette Bro, HeitmannBødtger, Uff e Christian, Meyer, Christian Niels, Jensen, Andreas Vestergaard, Baunbæk-knudsen, Gertrud, Petersen, Pelle Trier, Andersen, Stine, El-Wahhab, Ibrahim El-Said Abd, Morsy, Nesreen Elsayed, Shafiek, Hanaa, Sobh, Eman, Bertrand, Fabrice, Brun-Buisson, Christian, de Montmollin, Etienne, Fartoukh, Muriel, Messika, Jonathan, Tattevin, Pierre, Dreher, Michael, Kolditz, Martin, Meisinger, Matthias, Pletz, Mathias W, Hagel, Stefan, Rupp, Jan, Schaberg, Tom, Spielmanns, Marc, Siaw-Lartey, Beatrice, Dimakou, Katerina, Papapetrou, Dimosthenis, Tsigou, Evdoxia, Ampazis, Dimitrios, Bhatia, Mohit, Dhar, Raja, D’Souza, George, Garg, Rajiv, Koul, Parvaiz A, Mahesh, P A, Jayaraj, B S, Narayan, Kiran Vishnu, Udnur, Hirennappa B, Krishnamurthy, Shashi Bhaskara, Golshani, Keihan, Keatings, Vera M, Martin-Loeches, Ignacio, Maor, Yasmin, Strahilevitz, Jacob, Battaglia, Salvatore, Carrabba, Maria, Ceriana, Piero, Confalonieri, Marco, d’Arminio Monforte, Antonella, Del Prato, Bruno, De Rosa, Marino, Fantini, Riccardo, Fiorentino, Giuseppe, Gammino, Maria Antonia, Menzella, Francesco, Milani, Giuseppe, Nava, Stefano, Palmiero, Gerardo, Petrino, Roberta, Gabrielli, Barbra, Rossi, Paolo, Sorino, Claudio, Steinhilber, Gundi, Zanforlin, Alessandro, Kurahashi, Kiyoyasu, Bacha, Zeina Aoun, Ugalde, Daniel Barajas, Zuñiga, Omar Ceballos, Villegas, José F, Medenica, Milic, van de Garde, E M W, Mihsra, Deebya Raj, Shrestha, Poojan, Ridgeon, Elliott, Awokola, Babatunde Ishola, Nwankwo, Ogonna N O, Olufunlola, Adefuye Bolanle, Olumide, Segaolu, Ukwaja, Kingsley N, Irfan, Muhammad, Minarowski, Lukasz, Szymon, Skoczyński, Froes, Felipe, Leuschner, Pedro, Meireles, Mariana, Ferrão, Cláudia, Neves, João, Ravara, Sofia B, da Beira, Cova, Brocovschii, Victoria, Ion, Chesov, Rusu, Doina, Toma, Cristina, Chirita, Daniela, Birkun, Alexei, Kaluzhenina, Anna, Almotairi, Abdullah, Abdulbaqi, Zakeya, Bukhary, Ali, Edathodu, Jameela, Fathy, Amal, Enani, Abdullah Mushira Abdulaziz, Mohamed, Nazik Eltayeb, Memon, Jawed Ulhadi, Bogdanović, Nada, Milenkovic, Branislava, Pesut, Dragica, Borderìas, Luis, Garcia, Noel Manuel Bordon, Alarcón, Hugo Cabello, Cilloniz, Catia, Torres, Antoni, Diaz-Brito, Vicens, Casas, Xavier, González, Alicia Encabo, Fernández-Almira, Maria Luisa, Gallego, Miguel, Gaspar-GarcÍa, Inmaculada, del Castillo, Juan González, Victoria, Patricia Javaloyes, Martínez, Elena Laserna, de Molina, Rosa Malo, Marcos, Pedro J, Menéndez, Rosario, PandoSandova, Ana, Aymerich, Cristina Prat, del la Torre, Alicia Lacoma, García-Olivé, Ignasi, Rello, Jordi, Moyano, Silvia, Sanz, Francisco, Sibila, Oriol, Rodrigo-Troyano, Ana, Solé-Violán, Jordi, Uranga, Ane, van Boven, Job FM, Torra, Ester Vendrell, Pujol, Jordi Almirall, Feldman, Charles, Yum, Ho Kee, Fiogbe, Arnauld Attannon, Yangui, Ferdaous, Bilaceroglu, Semra, Dalar, Levent, Yilmaz, Ufuk, Bogomolov, Artemii, Elahi, Naheed, Dhasmana, Devesh J, Ions, Rhiannon, Skeemer, Julie, Woltmann, Gerrit, Hancock, Carole, Hill, Adam T, Rudran, Banu, Ruiz-Buitrago, Silvia, Campbell, Marion, Whitaker, Paul, Allen, Karen S, Brito, Veronica, Dietz, Jessica, Dysart, Claire E, Kellie, Susan M, Franco-Sadud, Ricardo A, Meier, Garnet, Gaga, Mina, Holland, Thomas L, Bergin, Stephen P, Kheir, Fayez, Landmeier, Mark, Lois, Manuel, Nair, Girish B, Patel, Hemali, Reyes, Katherine, Rodriguez-Cintron, William, Saito, Shigeki, Soni, Nilam J, Noda, Julio, Hinojosa, Cecilia I, Levine, Stephanie M, Angel, Luis F, Anzueto, Antonio, Whitlow, K Scott, Hipskind, John, Sukhija, Kunal, Wunderink, Richard G., Shah, Ray D, Mateyo, Kondwelani John, Carugati, Manuela, Aliberti, S, Sotgiu, G, Blasi, F, Gori, A, Menendez, R, Encheva, M, Gallego, M, Leuschner, P, Ruiz-Buitrago, S, Battaglia, S, Fantini, R, Pascual-Guardia, S, Marin-Corral, J, and Restrepo, M I
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Male ,0301 basic medicine ,Microbiology (medical) ,medicine.medical_specialty ,Community-acquired pneumonia ,030106 microbiology ,Antimicrobial treatment ,Prevalence ,Guideline ,Settore MED/10 - Malattie Dell'Apparato Respiratorio ,Guidelines ,Global Health ,medicine.disease_cause ,Immunocompromised Host ,03 medical and health sciences ,0302 clinical medicine ,Medical microbiology ,Internal medicine ,Epidemiology ,Streptococcus pneumoniae ,Pneumonia, Bacterial ,Humans ,Medicine ,030212 general & internal medicine ,Practice Patterns, Physicians' ,Aged ,Aged, 80 and over ,business.industry ,Correction ,General Medicine ,Middle Aged ,medicine.disease ,Anti-Bacterial Agents ,Community-Acquired Infections ,Hospitalization ,Pneumonia ,Infectious Diseases ,Practice Guidelines as Topic ,Pseudomonas aeruginosa ,Etiology ,Original Article ,Female ,Guideline Adherence ,business - Abstract
An accurate knowledge of the epidemiology of community-acquired pneumonia (CAP) is key for selecting appropriate antimicrobial treatments. Very few etiological studies assessed the appropriateness of empiric guideline recommendations at a multinational level. This study aims at the following: (i) describing the bacterial etiologic distribution of CAP and (ii) assessing the appropriateness of the empirical treatment recommendations by clinical practice guidelines (CPGs) for CAP in light of the bacterial pathogens diagnosed as causative agents of CAP. Secondary analysis of the GLIMP, a point-prevalence international study which enrolled adults hospitalized with CAP in 2015. The analysis was limited to immunocompetent patients tested for bacterial CAP agents within 24 h of admission. The CAP CPGs evaluated included the following: the 2007 and 2019 American Thoracic Society/Infectious Diseases Society of America (ATS/IDSA), the European Respiratory Society (ERS), and selected country-specific CPGs. Among 2564 patients enrolled, 35.3% had an identifiable pathogen. Streptococcus pneumoniae (8.2%) was the most frequently identified pathogen, followed by Pseudomonas aeruginosa (4.1%) and Klebsiella pneumoniae (3.4%). CPGs appropriately recommend covering more than 90% of all the potential pathogens causing CAP, with the exception of patients enrolled from Germany, Pakistan, and Croatia. The 2019 ATS/IDSA CPGs appropriately recommend covering 93.6% of the cases compared with 90.3% of the ERS CPGs (p
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- 2020
47. Chapter 20 - Cingulate subregions in posttraumatic stress disorder, chronic stress, and treatment
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Hinojosa, Cecilia A., Kaur, Navneet, VanElzakker, Michael B., and Shin, Lisa M.
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- 2019
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48. Targeting the Amygdala in a TMS Clinical Trial for PTSD.
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van Rooij, Sanne, Hinojosa, Cecilia, Teye-Botchway, Lois, Minton, Sean, Langhinrichsen-Rohling, Ryan, Job, Gregory, Ely, Timothy, Ressler, Kerry, Kaslow, Nadine, Rauch, Sheila, Jovanovic, Tanja, Holtzheimer, Paul, Calhoun, Vince, Riva-Posse, Patricio, Camprodon, Joan, and McDonald, William
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CLINICAL trials , *POST-traumatic stress disorder - Published
- 2024
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49. Impact of oral simvastatin therapy on acute lung injury in mice during pneumococcal pneumonia
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Boyd Angela R, Hinojosa Cecilia A, Rodriguez Perla J, and Orihuela Carlos J
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Microbiology ,QR1-502 - Abstract
Abstract Background Recent studies suggest that the reported protective effects of statins (HMG-CoA reductase inhibitors) against community-acquired pneumonia (CAP) and sepsis in humans may be due to confounders and a healthy user-effect. To directly test whether statins are protective against Streptococcus pneumoniae, the leading cause of CAP, we examined the impact of prolonged oral simvastatin therapy at physiologically relevant doses in a mouse model of pneumococcal pneumonia. BALB/c mice were placed on rodent chow containing 0 mg/kg (control), 12 mg/kg (low simvastatin diet [LSD]; corresponds to 1.0 mg/kg/day), or 120 mg/kg (high simvastatin diet [HSD]; corresponds to 10 mg/kg/day) simvastatin for four weeks, infected intratracheally with S. pneumoniae serotype 4 strain TIGR4, and sacrificed at 24, 36, or 42 h post-infection for assessment of lung histology, cytokine production, vascular leakage and edema, bacterial burden and bloodstream dissemination. Some mice received ampicillin at 12-h intervals beginning at 48 h post-infection and were monitored for survival. Immunoblots of homogenized lung samples was used to assess ICAM-1 production. Results Mice receiving HSD had reduced lung consolidation characterized by less macrophage and neutrophil infiltration and a significant reduction in the chemokines MCP-1 (P = 0.03) and KC (P = 0.02) and ICAM-1 in the lungs compared to control mice. HSD mice also had significantly lower bacterial titers in the blood at 36 (P = 0.007) and 42 (P = 0.03) hours post-infection versus controls. LSD had a more modest effect against S. pneumoniae but also resulted in reduced bacterial titers in the lungs and blood of mice after 42 h and a reduced number of infiltrated neutrophils. Neither LSD nor HSD mice had reduced mortality in a pneumonia model where mice received ampicillin 48 h after challenge. Conclusions Prolonged oral simvastatin therapy had a strong dose-dependent effect on protection against S. pneumoniae as evidenced by reduced neutrophil infiltration, maintenance of vascular integrity, and lowered chemokine production in the lungs of mice on HSD. Statin therapy also protected through reduced bacterial burden in the lungs. Despite these protective correlates, mortality in the simvastatin-receiving cohorts was equivalent to controls. Thus, oral simvastatin at physiologically relevant doses only modestly protects against pneumococcal pneumonia.
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- 2012
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50. An international perspective on hospitalized patients with viral community-acquired pneumonia
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Radovanovic, Dejan, primary, Sotgiu, Giovanni, additional, Jankovic, Mateja, additional, Mahesh, Padukudru Anand, additional, Marcos, Pedro Jorge, additional, Abdalla, Mohamed I., additional, Di Pasquale, Marta Francesca, additional, Gramegna, Andrea, additional, Terraneo, Silvia, additional, Blasi, Francesco, additional, Santus, Pierachille, additional, Aliberti, Stefano, additional, Reyes, Luis F., additional, Restrepo, Marcos I., additional, Aruj, Patricia Karina, additional, Attorri, Silvia, additional, Barimboim, Enrique, additional, Caeiro, Juan Pablo, additional, Garzón, María I., additional, Cambursano, Victor Hugo, additional, Ceccato, Adrian, additional, Chertcoff, Julio, additional, Cordon Díaz, Ariel, additional, de Vedia, Lautaro, additional, Ganaha, Maria Cristina, additional, Lambert, Sandra, additional, Lopardo, Gustavo, additional, Luna, Carlos M., additional, Malberti, Alessio Gerardo, additional, Morcillo, Nora, additional, Tartara, Silvina, additional, Pensotti, Claudia, additional, Pereyra, Betiana, additional, Scapellato, Pablo Gustavo, additional, Stagnaro, Juan Pablo, additional, Shah, Sonali, additional, Lötsch, Felix, additional, Thalhammer, Florian, additional, Anseeuw, Kurt, additional, Francois, Camille A., additional, Van Braeckel, Eva, additional, Vincent, Jean Louis, additional, Djimon, Marcel Zannou, additional, Aranha Nouér, Simone, additional, Chipev, Peter, additional, Encheva, Milena, additional, Miteva, Darina, additional, Petkova, Diana, additional, Balkissou, Adamou Dodo, additional, Pefura Yone, Eric Walter, additional, Mbatchou Ngahane, Bertrand Hugo, additional, Shen, Ning, additional, Xu, Jin-fu, additional, Bustamante Rico, Carlos Andres, additional, Buitrago, Ricardo, additional, Pereira Paternina, Fernando Jose, additional, Kayembe Ntumba, Jean-Marie, additional, Vladic-Carevic, Vesna, additional, Jakopovic, Marko, additional, Matkovic, Zinka, additional, Mitrecic, Ivan, additional, Bouchy Jacobsson, Marie-Laure, additional, Bro Christensen, Anette, additional, Bødtger, Uffe, additional, Meyer, Christian Niels, additional, Vestergaard Jensen, Andreas, additional, El-Said Abd El-Wahhab, Ibrahim, additional, Elsayed Morsy, Nesreen, additional, Shafiek, Hanaa, additional, Sobh, Eman, additional, Abdulsemed, Kedir Abdella, additional, Bertrand, Fabrice, additional, Brun-Buisson, Christian, additional, de Montmollin, Etienne, additional, Fartoukh, Muriel, additional, Messika, Jonathan, additional, Tattevin, Pierre, additional, Khoury, Abdo, additional, Ebruke, Bernard, additional, Dreher, Michael, additional, Kolditz, Martin, additional, Meisinger, Matthias, additional, Pletz, Mathias W., additional, Hagel, Stefan, additional, Rupp, Jan, additional, Schaberg, Tom, additional, Spielmanns, Marc, additional, Creutz, Petra, additional, Suttorp, Norton, additional, Siaw-Lartey, Beatrice, additional, Dimakou, Katerina, additional, Papapetrou, Dimosthenis, additional, Tsigou, Evdoxia, additional, Ampazis, Dimitrios, additional, Kaimakamis, Evangelos, additional, Bhatia, Mohit, additional, Dhar, Raja, additional, D’Souza, George, additional, Garg, Rajiv, additional, Koul, Parvaiz A., additional, Jayaraj, B.S., additional, Narayan, Kiran Vishnu, additional, Udnur, Hirennappa B., additional, Krishnamurthy, Shashi Bhaskara, additional, Kant, Surya, additional, Swarnakar, Rajesh, additional, Salvi, Sundeep, additional, Limaye, Sneha, additional, Golshani, Keihan, additional, Keatings, Vera M., additional, Martin-Loeches, Ignacio, additional, Maor, Yasmin, additional, Strahilevitz, Jacob, additional, Battaglia, Salvatore, additional, Carrabba, Maria, additional, Ceriana, Piero, additional, Confalonieri, Marco, additional, d’Arminio Monforte, Antonella, additional, Del Prato, Bruno, additional, De Rosa, Marino, additional, Fantini, Riccardo, additional, Fiorentino, Giuseppe, additional, Gammino, Maria Antonia, additional, Menzella, Francesco, additional, Milani, Giuseppe, additional, Nava, Stefano, additional, Palmiero, Gerardo, additional, Petrino, Roberta, additional, Gabrielli, Barbra, additional, Rossi, Paolo, additional, Sorino, Claudio, additional, Steinhilber, Gundi, additional, Zanforlin, Alessandro, additional, Franzetti, Fabio, additional, Carone, Mauro, additional, Patella, Vincenzo, additional, Scarlata, Simone, additional, Comel, Andrea, additional, Kurahashi, Kiyoyasu, additional, Aoun Bacha, Zeina, additional, Barajas Ugalde, Daniel, additional, Ceballos Zuñiga, Omar, additional, Villegas, José F., additional, Medenica, Milic, additional, van de Garde, E.M.W., additional, Raj Mihsra, Deebya, additional, Shrestha, Poojan, additional, Ridgeon, Elliott, additional, Ishola Awokola, Babatunde, additional, Nwankwo, Ogonna N.O., additional, Olufunlola, Adefuye Bolanle, additional, Olumide, Segaolu, additional, Ukwaja, Kingsley N., additional, Irfan, Muhammad, additional, Minarowski, Lukasz, additional, Szymon, Skoczyński, additional, Froes, Felipe, additional, Leuschner, Pedro, additional, Meireles, Mariana, additional, Ferrão, Cláudia, additional, Neves, João, additional, Ravara, Sofia B., additional, Brocovschii, Victoria, additional, Ion, Chesov, additional, Rusu, Doina, additional, Toma, Cristina, additional, Chirita, Daniela, additional, Dorobat, Carmen Mihaela, additional, Birkun, Alexei, additional, Kaluzhenina, Anna, additional, Almotairi, Abdullah, additional, Bukhary, Zakeya Abdulbaqi Ali, additional, Edathodu, Jameela, additional, Fathy, Amal, additional, Mushira Abdulaziz Enani, Abdullah, additional, Eltayeb Mohamed, Nazik, additional, Ulhadi Memon, Jawed, additional, Bella, Abdelhaleem, additional, Bogdanović, Nada, additional, Milenkovic, Branislava, additional, Pesut, Dragica, additional, Borderìas, Luis, additional, Bordon Garcia, Noel Manuel, additional, Cabello Alarcón, Hugo, additional, Cilloniz, Catia, additional, Torres, Antoni, additional, Diaz-Brito, Vicens, additional, Casas, Xavier, additional, Encabo González, Alicia, additional, Fernández-Almira, Maria Luisa, additional, Gallego, Miguel, additional, Gaspar-GarcÍa, Inmaculada, additional, González Del Castillo, Juan, additional, Javaloyes Victoria, Patricia, additional, Laserna Martínez, Elena, additional, Malo de Molina, Rosa, additional, Menéndez, Rosario, additional, Pando-Sandoval, Ana, additional, Prat Aymerich, Cristina, additional, Lacoma de la Torre, Alicia, additional, García-Olivé, Ignasi, additional, Rello, Jordi, additional, Moyano, Silvia, additional, Sanz, Francisco, additional, Sibila, Oriol, additional, Rodrigo-Troyano, Ana, additional, Solé-Violán, Jordi, additional, Uranga, Ane, additional, van Boven, Job F.M., additional, Vendrell Torra, Ester, additional, Pujol, Jordi Almirall, additional, Feldman, Charles, additional, Kee Yum, Ho, additional, Fiogbe, Arnauld Attannon, additional, Yangui, Ferdaous, additional, Bilaceroglu, Semra, additional, Dalar, Levent, additional, Yilmaz, Ufuk, additional, Bogomolov, Artemii, additional, Elahi, Naheed, additional, Dhasmana, Devesh J., additional, Feneley, Andrew, additional, Hancock, Carole, additional, Hill, Adam T., additional, Rudran, Banu, additional, Ruiz-Buitrago, Silvia, additional, Campbell, Marion, additional, Whitaker, Paul, additional, Youzguin, Alexander, additional, Singanayagam, Anika, additional, Allen, Karen S., additional, Brito, Veronica, additional, Dietz, Jessica, additional, Dysart, Claire E., additional, Kellie, Susan M., additional, Franco-Sadud, Ricardo A., additional, Meier, Garnet, additional, Gaga, Mina, additional, Holland, Thomas L., additional, Bergin, Stephen P., additional, Kheir, Fayez, additional, Landmeier, Mark, additional, Lois, Manuel, additional, Nair, Girish B., additional, Patel, Hemali, additional, Reyes, Katherine, additional, Rodriguez-Cintron, William, additional, Saito, Shigeki, additional, Soni, Nilam J., additional, Noda, Julio, additional, Hinojosa, Cecilia I., additional, Levine, Stephanie M., additional, Angel, Luis F., additional, Anzueto, Antonio, additional, Scott Whitlow, K., additional, Hipskind, John, additional, Sukhija, Kunal, additional, Totten, Vicken, additional, Wunderink, Richard G., additional, Shah, Ray D., additional, Mateyo, Kondwelani John, additional, Carugati, Manuela, additional, Morosi, Manuela, additional, and Monge, Elisa, additional
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