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Your search keyword '"Hiner, Cheryl J."' showing total 5 results
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5 results on '"Hiner, Cheryl J."'

1. Fluorescein angiographic characteristics of macular holes before and after vitrectomy with transforming growth factor beta-2

Author

Thompson, John T., Hiner, Cheryl J., Glaser, Bert M., Gordon, Alan J., Murphy, Robert P., and Sjaarda, Raymond N.

Subjects
Vitrectomy -- Evaluation, Fluorescence angiography -- Analysis, Retinal degeneration -- Analysis, Health
Abstract

We evaluated the fluorescein angiographic features of full-thickness macular holes before and after vitrectomy, fluid-gas exchange, and instillation of transforming growth factor beta-2 in 43 eyes in a masked fashion to evaluate the angiographic characteristics of macular holes preoperatively and the changes that occur with successful and unsuccessful closure of the macular hole. Hyperfluorescence was present in the base of the macular hole preoperatively in 34 of 43 eyes (79.1%), was questionable in eight of 43 eyes (18.6%), and was definitely absent in only one of 43 eyes (2.3%). The hyperfluorescence in the base of the macular hole disappeared in 19 of 20 eyes (95%) with successful closure of the macular hole (P < .00001) and appeared to be caused by blocked fluorescence at the site of the macular hole. The photographic features of eyes with unsuccessful closure of the macular hole changed little, except that the size of the cuff of neurosensory detachment around the hole increased and was associated with decreased postoperative visual acuity. These angiographic changes support the presence of a glial tissue plug bridging a small defect in the fovea of eyes with successful closure of a macular hole.

Published
1994

5. Reproducibility of Gradings of Retinal Photographs in Eyes with Subfoveal Choroidal Neovascularization and Age-Related Macular Degeneration in the Macular Photocoagulation Study.

Author

Jefferys, Joan L., Alexander, Judith, Hiner, Cheryl J., Javornik, Noreen B., Smith, Rochelle E., Bressler, Neil M., and Hawkins, Barbara S.

Subjects
RETINAL degeneration, RETINAL diseases, LIGHT amplifiers, OPTICAL parametric oscillators, NEOVASCULARIZATION, BLOOD-vessel development
Abstract

Purpose: To assess the reproducibility of the evaluation of color photographs and fluorescein angiograms of the macula of each eye for patients enrolled in the Macular Photocoagulation Study (MPS) trials of laser photocoagulation of subfoveal choroidal neovascularization (CNV) secondary to age-related macular degeneration. Methods: A total of 65 pre-enrollment and 26 posttreatment sets of photographs were regraded. The two gradings were compared on selected items judged to be of primary importance with respect to the role of the MPS Reading Center. Results: Agreement on eligibility of the neovascular lesion for an MPS trial was 88% (kappa statistic = 0.59); agreement on the size of the lesion was 86% (kappa statistic = 0.80); agreement on whether the lesion was covered by heavy treatment was 69% (kappa statistic = 0.35); and agreement on whether the treatment was in compliance with the study protocol was 73% (kappa statistic = 0.06). Conclusions: Interpretation of photographs of eyes with CNV secondary to age-related macular degeneration for eligibility and size of the lesion was reproducible in the MPS. However, adequacy of laser photocoagulation treatment could not be determined reliably from photographs. [ABSTRACT FROM AUTHOR]

Published
2008
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