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10. Real-world utility of implantable loop recorders

Author

Plappert, C, primary, Lacour, P, additional, Boldt, L H, additional, Parwani, A, additional, Baehr, F, additional, Wieland, L, additional, Schoeppenthau, D, additional, Dagres, N, additional, Hindricks, G, additional, and Blaschke, F, additional

Published
2024
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16. 2024 European Heart Rhythm Association/Heart Rhythm Society/Asia Pacific Heart Rhythm Society/Latin American Heart Rhythm Society expert consensus statement on catheter and surgical ablation of atrial fibrillation

Author

Tzeis, S, Gerstenfeld, EP, Kalman, J, Saad, EB, Shamloo, AS, Andrade, JG, Barbhaiya, CR, Baykaner, T, Boveda, S, Calkins, H, Chan, N-Y, Chen, M, Chen, S-A, Dagres, N, Damiano, RJ, De Potter, T, Deisenhofer, I, Derval, N, Di Biase, L, Duytschaever, M, Dyrda, K, Hindricks, G, Hocini, M, Kim, Y-H, la Meir, M, Merino, JL, Michaud, GF, Natale, A, Nault, I, Nava, S, Nitta, T, O'Neill, M, Pak, H-N, Piccini, JP, Puererfellner, H, Reichlin, T, Saenz, LC, Sanders, P, Schilling, R, Schmidt, B, Supple, GE, Thomas, KL, Tondo, C, Verma, A, Wan, EY, Tzeis, S, Gerstenfeld, EP, Kalman, J, Saad, EB, Shamloo, AS, Andrade, JG, Barbhaiya, CR, Baykaner, T, Boveda, S, Calkins, H, Chan, N-Y, Chen, M, Chen, S-A, Dagres, N, Damiano, RJ, De Potter, T, Deisenhofer, I, Derval, N, Di Biase, L, Duytschaever, M, Dyrda, K, Hindricks, G, Hocini, M, Kim, Y-H, la Meir, M, Merino, JL, Michaud, GF, Natale, A, Nault, I, Nava, S, Nitta, T, O'Neill, M, Pak, H-N, Piccini, JP, Puererfellner, H, Reichlin, T, Saenz, LC, Sanders, P, Schilling, R, Schmidt, B, Supple, GE, Thomas, KL, Tondo, C, Verma, A, and Wan, EY

Abstract

In the last three decades, ablation of atrial fibrillation (AF) has become an evidence-based safe and efficacious treatment for managing the most common cardiac arrhythmia. In 2007, the first joint expert consensus document was issued, guiding healthcare professionals involved in catheter or surgical AF ablation. Mounting research evidence and technological advances have resulted in a rapidly changing landscape in the field of catheter and surgical AF ablation, thus stressing the need for regularly updated versions of this partnership which were issued in 2012 and 2017. Seven years after the last consensus, an updated document was considered necessary to define a contemporary framework for selection and management of patients considered for or undergoing catheter or surgical AF ablation. This consensus is a joint effort from collaborating cardiac electrophysiology societies, namely the European Heart Rhythm Association, the Heart Rhythm Society, the Asia Pacific Heart Rhythm Society, and the Latin American Heart Rhythm Society .

Published
2024

17. Kurzversion der 2. Auflage der deutsch-österreichischen S3-Leitlinie „Infarkt-bedingter Kardiogener Schock – Diagnose, Monitoring und Therapie“

Author

Werdan, K., Boeken, U., Briegel, M. J., Buerke, M., Geppert, A., Janssens, U., Kelm, M., Michels, G., Pilarczyk, K., Schlitt, A., Thiele, H., Willems, S., Zeymer, U., Zwißler, B., Delle-Karth, G., Ferrari, M., Figulla, H., Heller, A., Hindricks, G., Pichler-Cetin, E., Pieske, B. M., Prondzinsky, R., Thielmann, M., Bauersachs, J., Kopp, I., and Ruß, M.

Published
2021
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18. Kurzversion der 2. Auflage der deutsch-österreichischen S3-Leitlinie „Infarkt-bedingter Kardiogener Schock – Diagnose, Monitoring und Therapie“

Author

Werdan, K., Boeken, U., Briegel, M. J., Buerke, M., Geppert, A., Janssens, U., Kelm, M., Michels, G., Pilarczyk, K., Schlitt, A., Thiele, H., Willems, S., Zeymer, U., Zwißler, B., Delle-Karth, G., Ferrari, M., Figulla, H., Heller, A., Hindricks, G., Pichler-Cetin, E., Pieske, B. M., Prondzinsky, R., Thielmann, M., Bauersachs, J., Kopp, I., and Ruß, M.

Published
2020
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20. The Lancet Commission to reduce the global burden of sudden cardiac death: a call for multidisciplinary action

Author

Marijon, E, Narayanan, K, Smith, K, Barra, S, Basso, C, Blom, M, Crotti, L, D'Avila, A, Deo, R, Dumas, F, Dzudie, A, Farrugia, A, Greeley, K, Hindricks, G, Hua, W, Ingles, J, Iwami, T, Junttila, J, Koster, R, Le Polain De Waroux, J, Olasveengen, T, Ong, M, Papadakis, M, Sasson, C, Shin, S, Tse, H, Tseng, Z, Van Der Werf, C, Folke, F, Albert, C, Winkel, B, Marijon E., Narayanan K., Smith K., Barra S., Basso C., Blom M. T., Crotti L., D'Avila A., Deo R., Dumas F., Dzudie A., Farrugia A., Greeley K., Hindricks G., Hua W., Ingles J., Iwami T., Junttila J., Koster R. W., Le Polain De Waroux J. -B., Olasveengen T. M., Ong M. E. H., Papadakis M., Sasson C., Shin S. D., Tse H. -F., Tseng Z., Van Der Werf C., Folke F., Albert C. M., Winkel B. G., Marijon, E, Narayanan, K, Smith, K, Barra, S, Basso, C, Blom, M, Crotti, L, D'Avila, A, Deo, R, Dumas, F, Dzudie, A, Farrugia, A, Greeley, K, Hindricks, G, Hua, W, Ingles, J, Iwami, T, Junttila, J, Koster, R, Le Polain De Waroux, J, Olasveengen, T, Ong, M, Papadakis, M, Sasson, C, Shin, S, Tse, H, Tseng, Z, Van Der Werf, C, Folke, F, Albert, C, Winkel, B, Marijon E., Narayanan K., Smith K., Barra S., Basso C., Blom M. T., Crotti L., D'Avila A., Deo R., Dumas F., Dzudie A., Farrugia A., Greeley K., Hindricks G., Hua W., Ingles J., Iwami T., Junttila J., Koster R. W., Le Polain De Waroux J. -B., Olasveengen T. M., Ong M. E. H., Papadakis M., Sasson C., Shin S. D., Tse H. -F., Tseng Z., Van Der Werf C., Folke F., Albert C. M., and Winkel B. G.

Abstract

Despite major advancements in cardiovascular medicine, sudden cardiac death (SCD) continues to be an enormous medical and societal challenge, claiming millions of lives every year. Efforts to prevent SCD are hampered by imperfect risk prediction and inadequate solutions to specifically address arrhythmogenesis. Although resuscitation strategies have witnessed substantial evolution, there is a need to strengthen the organisation of community interventions and emergency medical systems across varied locations and health-care structures. With all the technological and medical advances of the 21st century, the fact that survival from sudden cardiac arrest (SCA) remains lower than 10% in most parts of the world is unacceptable. Recognising this urgent need, the Lancet Commission on SCD was constituted, bringing together 30 international experts in varied disciplines. Consistent progress in tackling SCD will require a completely revamped approach to SCD prevention, with wide-sweeping policy changes that will empower the development of both governmental and community-based programmes to maximise survival from SCA, and to comprehensively attend to survivors and decedents’ families after the event. International collaborative efforts that maximally leverage and connect the expertise of various research organisations will need to be prioritised to properly address identified gaps. The Commission places substantial emphasis on the need to develop a multidisciplinary strategy that encompasses all aspects of SCD prevention and treatment. The Commission provides a critical assessment of the current scientific efforts in the field, and puts forth key recommendations to challenge, activate, and intensify efforts by both the scientific and global community with new directions, research, and innovation to reduce the burden of SCD worldwide.

Published
2023

26. Preventive or Deferred Ablation of Ventricular Tachycardia in Patients With Ischemic Cardiomyopathy and Implantable Defibrillator (BERLIN VT): A Multicenter Randomized Trial

Author

Willems, Stephan, Tilz, Roland Richard, Steven, Daniel, Kääb, Stefan, Wegscheider, Karl, Gellér, László, Meyer, Christian, Heeger, Christian-Hendrik, Metzner, Andreas, Sinner, Moritz F., Schlüter, Michael, Nordbeck, Peter, Eckardt, Lars, Bogossian, Harilaos, Sultan, Arian, Wenzel, Beate, Kuck, Karl-Heinz, Piorkowski, C., Lebedev, D., Kautzner, J., Sticherling, C., Deneke, T., Rostock, T., Ukena, C., Kuniss, M., Makimoto, H., Hindricks, G., Bänsch, D., Schreieck, J., Kolb, C., Geller, J., Pokushalov, E., Gutleben, K., Sommer, P., Boldt, L.H., and Parwani, A.

Published
2020
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28. P-wave duration and interatrial block as predictors of new-onset atrial fibrillation: A systematic review and meta-analysis

Author

Koutalas, E, primary, Zagoridis, K, additional, Intzes, S, additional, Symeonidou, M, additional, Zagoridou, N, additional, Karagogos, K, additional, Spanoudakis, E, additional, Kanoupakis, E, additional, Kochiadakis, G, additional, Dinov, B, additional, Dagres, N, additional, Hindricks, G, additional, Bollmann, A, additional, and Nedios, S, additional

Published
2023
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34. STereotactic Arrhythmia Radioablation (STAR): the Standardized Treatment and Outcome Platform for Stereotactic Therapy Of Re-entrant tachycardia by a Multidisciplinary consortium (STOPSTORM.eu) and review of current patterns of STAR practice in Europe

Author

Grehn, M., Mandija, S., Miszczyk, M., Krug, D., Tomasik, B., Stickney, K. E., Alcantara, P., Alongi, F., Anselmino, M., Aranda, R. S., Balgobind, B. V., Boda-Heggemann, J., Boldt, L.-H., Bottoni, N., Cvek, J., Elicin, O., Ferrari, G. M., Hassink, R. J., Hazelaar, C., Hindricks, G., Hurkmans, C., Iotti, C., Jadczyk, T., Jiravsky, O., Jumeau, R., Kristiansen, S. B., Levis, M., López, M. A., Martí-Almor, J., Mehrhof, F., Møller, D. S., Molon, G., Ouss, A., Peichl, P., Plasek, J., Postema, P. G., Quesada, A., Reichlin, T., Rordorf, R., Rudic, B., Saguner, A. M., Ter, B., Rachel, M. A., Torrecilla, J. L., (0000-0001-9550-9050) Troost, E. G. C., Vitolo, V., Andratschke, N., Zeppenfeld, K., Blamek, S., Fast, M., Panfilis, L., Blanck, O., Pruvot, E., Verhoeff, J. J. C., Grehn, M., Mandija, S., Miszczyk, M., Krug, D., Tomasik, B., Stickney, K. E., Alcantara, P., Alongi, F., Anselmino, M., Aranda, R. S., Balgobind, B. V., Boda-Heggemann, J., Boldt, L.-H., Bottoni, N., Cvek, J., Elicin, O., Ferrari, G. M., Hassink, R. J., Hazelaar, C., Hindricks, G., Hurkmans, C., Iotti, C., Jadczyk, T., Jiravsky, O., Jumeau, R., Kristiansen, S. B., Levis, M., López, M. A., Martí-Almor, J., Mehrhof, F., Møller, D. S., Molon, G., Ouss, A., Peichl, P., Plasek, J., Postema, P. G., Quesada, A., Reichlin, T., Rordorf, R., Rudic, B., Saguner, A. M., Ter, B., Rachel, M. A., Torrecilla, J. L., (0000-0001-9550-9050) Troost, E. G. C., Vitolo, V., Andratschke, N., Zeppenfeld, K., Blamek, S., Fast, M., Panfilis, L., Blanck, O., Pruvot, E., and Verhoeff, J. J. C.

Abstract

The EU Horizon 2020 Framework-funded Standardized Treatment and Outcome Platform for Stereotactic Therapy Of Re-entrant tachycardia by a Multidisciplinary (STOPSTORM) consortium has been established as a large research network for investigating STereotactic Arrhythmia Radioablation (STAR) for ventricular tachycardia (VT). The aim is to provide a pooled treatment database to evaluate patterns of practice and outcomes of STAR and finally to harmonize STAR within Europe. The consortium comprises 31 clinical and research institutions. The project is divided into nine work packages (WPs): (i) observational cohort; (ii) standardization and harmonization of target delineation; (iii) harmonized prospective cohort; (iv) quality assurance (QA); (v) analysis and evaluation; (vi, ix) ethics and regulations; and (vii, viii) project coordination and dissemination. To provide a review of current clinical STAR practice in Europe, a comprehensive questionnaire was performed at project start. The STOPSTORM Institutions' experience in VT catheter ablation (83% ≥ 20 ann.) and stereotactic body radiotherapy (59% > 200 ann.) was adequate, and 84 STAR treatments were performed until project launch, while 8/22 centres already recruited VT patients in national clinical trials. The majority currently base their target definition on mapping during VT (96%) and/or pace mapping (75%), reduced voltage areas (63%), or late ventricular potentials (75%) during sinus rhythm. The majority currently apply a single-fraction dose of 25 Gy while planning techniques and dose prescription methods vary greatly. The current clinical STAR practice in the STOPSTORM consortium highlights potential areas of optimization and harmonization for substrate mapping, target delineation, motion management, dosimetry, and QA, which will be addressed in the various WPs. © The Author(s) 2023. Published by Oxford University Press on behalf of the European Society of Cardiology.

Published
2023

41. Impact of Coronavirus Disease 2019 (COVID-19) Outbreak on Acute Admissions at the Emergency and Cardiology Departments Across Europe

Author

Sokolski, M, Gajewski, P, Zymliński, R, Biegus, J, Berg, J, Bor, W, Braunschweig, F, Caldeira, D, Cuculi, F, D'Elia, E, Edes, I, Garus, M, Greenwood, J, Halfwerk, F, Hindricks, G, Knuuti, J, Kristensen, S, Landmesser, U, Lund, L, Lyon, A, Mebazaa, A, Merkely, B, Nawrocka-Millward, S, Pinto, F, Ruschitzka, F, Semedo, E, Senni, M, Sepehri Shamloo, A, Sorensen, J, Stengaard, C, Thiele, H, Toggweiler, S, Tukiendorf, A, Verhorst, P, Wright, D, Zamorano, P, Zuber, M, Narula, J, Bax, J, Ponikowski, P, Sokolski M, Gajewski P, Zymliński R, Biegus J, Berg JMT, Bor W, Braunschweig F, Caldeira D, Cuculi F, D'Elia E, Edes IF, Garus M, Greenwood JP, Halfwerk FR, Hindricks G, Knuuti J, Kristensen SD, Landmesser U, Lund LH, Lyon A, Mebazaa A, Merkely B, Nawrocka-Millward S, Pinto FJ, Ruschitzka F, Semedo E, Senni M, Sepehri Shamloo A, Sorensen J, Stengaard C, Thiele H, Toggweiler S, Tukiendorf A, Verhorst PM, Wright DJ, Zamorano P, Zuber M, Narula J, Bax JJ, Ponikowski P, Sokolski, M, Gajewski, P, Zymliński, R, Biegus, J, Berg, J, Bor, W, Braunschweig, F, Caldeira, D, Cuculi, F, D'Elia, E, Edes, I, Garus, M, Greenwood, J, Halfwerk, F, Hindricks, G, Knuuti, J, Kristensen, S, Landmesser, U, Lund, L, Lyon, A, Mebazaa, A, Merkely, B, Nawrocka-Millward, S, Pinto, F, Ruschitzka, F, Semedo, E, Senni, M, Sepehri Shamloo, A, Sorensen, J, Stengaard, C, Thiele, H, Toggweiler, S, Tukiendorf, A, Verhorst, P, Wright, D, Zamorano, P, Zuber, M, Narula, J, Bax, J, Ponikowski, P, Sokolski M, Gajewski P, Zymliński R, Biegus J, Berg JMT, Bor W, Braunschweig F, Caldeira D, Cuculi F, D'Elia E, Edes IF, Garus M, Greenwood JP, Halfwerk FR, Hindricks G, Knuuti J, Kristensen SD, Landmesser U, Lund LH, Lyon A, Mebazaa A, Merkely B, Nawrocka-Millward S, Pinto FJ, Ruschitzka F, Semedo E, Senni M, Sepehri Shamloo A, Sorensen J, Stengaard C, Thiele H, Toggweiler S, Tukiendorf A, Verhorst PM, Wright DJ, Zamorano P, Zuber M, Narula J, Bax JJ, and Ponikowski P

Abstract

Purpose: We evaluated whether the severe acute respiratory syndrome coronavirus 2 (SARS-COV-2) pandemic was associated with changes in the pattern of acute cardiovascular admissions across European centers. Methods: We set-up a multicenter, multinational, pan-European observational registry in 15 centers from 12 countries. All consecutive acute admissions to emergency departments and cardiology departments throughout a 1-month period during the COVID-19 outbreak were compared with an equivalent 1-month period in 2019. The acute admissions to cardiology departments were classified into 5 major categories: acute coronary syndrome, acute heart failure, arrhythmia, pulmonary embolism, and other. Results: Data from 54,331 patients were collected and analyzed. Nine centers provided data on acute admissions to emergency departments comprising 50,384 patients: 20,226 in 2020 compared with 30,158 in 2019 (incidence rate ratio [IRR] with 95% confidence interval [95%CI]: 0.66 [0.58-0.76]). The risk of death at the emergency departments was higher in 2020 compared to 2019 (odds ratio [OR] with 95% CI: 4.1 [3.0-5.8], P < 0.0001). All 15 centers provided data on acute cardiology departments admissions: 3007 patients in 2020 and 4452 in 2019; IRR (95% CI): 0.68 (0.64-0.71). In 2020, there were fewer admissions with IRR (95% CI): acute coronary syndrome: 0.68 (0.63-0.73); acute heart failure: 0.65 (0.58-0.74); arrhythmia: 0.66 (0.60-0.72); and other: 0.68(0.62-0.76). We found a relatively higher percentage of pulmonary embolism admissions in 2020: odds ratio (95% CI): 1.5 (1.1-2.1), P = 0.02. Among patients with acute coronary syndrome, there were fewer admissions with unstable angina: 0.79 (0.66-0.94); non-ST segment elevation myocardial infarction: 0.56 (0.50-0.64); and ST-segment elevation myocardial infarction: 0.78 (0.68-0.89). Conclusion: In the European centers during the COVID-19 outbreak, there were fewer acute cardiovascular admissions. Also, fewer patients were admitt

Published
2021

47. 2019 ESC Guidelines for themanagement of patients with supraventricular tachycardia

Author

Brugada, J, Katritsis, D, Arbelo, E, Arribas, F, Bax, J, Blomstrom-Lundqvist, C, Calkins, H, Corrado, D, Deftereos, S, Diller, G, Gomez-Doblas, J, Gorenek, B, Grace, A, Ho, S, Kaski, J, Kuck, K, Lambiase, P, Sacher, F, Sarquella-Brugada, G, Suwalski, P, Zaza, A, De Potter, T, Sticherling, C, Aboyans, V, Basso, C, Bocchiardo, M, Budts, W, Delgado, V, Dobrev, D, Fitzsimons, D, Gevaert, S, Heidbuchel, H, Hindricks, G, Hlivak, P, Kanagaratnam, P, Katus, H, Kautzner, J, Kriebel, T, Lancellotti, P, Landmesser, U, Leclercq, C, Lewis, B, Lopatin, Y, Merkely, B, Paul, T, Pavlovic, N, Petersen, S, Petronio, A, Potpara, T, Roffi, M, Scherr, D, Shlyakhto, E, Simpson, I, Zeppenfeld, K, Windecker, S, Baigent, C, Collet, J, Dean, V, Gale, C, Grobbee, D, Halvorsen, S, Iung, B, Juni, P, Lettino, M, Mueller, C, Richter, D, Sousa-Uva, M, Touyz, R, Amara, W, Grigoryan, S, Podczeck-Schweighofer, A, Chasnoits, A, Vandekerckhove, Y, Sokolovich, S, Traykov, V, Skoric, B, Papasavvas, E, Riahi, S, Kampus, P, Parikka, H, Piot, O, Etsadashvili, K, Stellbrink, C, Manolis, A, Csanadi, Z, Gudmundsson, K, Erwin, J, Barsheshet, A, De Ponti, R, Abdrakhmanov, A, Jashari, H, Lunegova, O, Jubele, K, Refaat, M, Puodziukynas, A, Groben, L, Grosu, A, Ibtissam, F, Trines, S, Poposka, L, Haugaa, K, Kowalski, O, Cavaco, D, Dobreanu, D, Mikhaylov, E, Zavatta, M, Nebojsa, M, Ferreira-Gonzalez, I, Juhlin, T, Reichlin, T, Haouala, H, Akgun, T, Gupta, D, Brugada J., Katritsis D. G., Arbelo E., Arribas F., Bax J. J., Blomstrom-Lundqvist C., Calkins H., Corrado D., Deftereos S. G., Diller G. -P., Gomez-Doblas J. J., Gorenek B., Grace A., Ho S. Y., Kaski J. -C., Kuck K. -H., Lambiase P. D., Sacher F., Sarquella-Brugada G., Suwalski P., Zaza A., De Potter T., Sticherling C., Aboyans V., Basso C., Bocchiardo M., Budts W., Delgado V., Dobrev D., Fitzsimons D., Gevaert S., Heidbuchel H., Hindricks G., Hlivak P., Kanagaratnam P., Katus H., Kautzner J., Kriebel T., Lancellotti P., Landmesser U., Leclercq C., Lewis B., Lopatin Y., Merkely B., Paul T., Pavlovic N., Petersen S., Petronio A. S., Potpara T., Roffi M., Scherr D., Shlyakhto E., Simpson I. A., Zeppenfeld K., Windecker S., Baigent C., Collet J. -P., Dean V., Gale C. P., Grobbee D. E., Halvorsen S., Iung B., Juni P., Lettino M., Mueller C., Richter D. J., Sousa-Uva M., Touyz R. M., Amara W., Grigoryan S., Podczeck-Schweighofer A., Chasnoits A., Vandekerckhove Y., Sokolovich S., Traykov V., Skoric B., Papasavvas E., Riahi S., Kampus P., Parikka H., Piot O., Etsadashvili K., Stellbrink C., Manolis A. S., Csanadi Z., Gudmundsson K., Erwin J., Barsheshet A., De Ponti R., Abdrakhmanov A., Jashari H., Lunegova O., Jubele K., Refaat M. M., Puodziukynas A., Groben L., Grosu A., Ibtissam F., Trines S. A., Poposka L., Haugaa K. H., Kowalski O., Cavaco D., Dobreanu D., Mikhaylov E. N., Zavatta M., Nebojsa M., Ferreira-Gonzalez I., Juhlin T., Reichlin T., Haouala H., Akgun T., Gupta D., Brugada, J, Katritsis, D, Arbelo, E, Arribas, F, Bax, J, Blomstrom-Lundqvist, C, Calkins, H, Corrado, D, Deftereos, S, Diller, G, Gomez-Doblas, J, Gorenek, B, Grace, A, Ho, S, Kaski, J, Kuck, K, Lambiase, P, Sacher, F, Sarquella-Brugada, G, Suwalski, P, Zaza, A, De Potter, T, Sticherling, C, Aboyans, V, Basso, C, Bocchiardo, M, Budts, W, Delgado, V, Dobrev, D, Fitzsimons, D, Gevaert, S, Heidbuchel, H, Hindricks, G, Hlivak, P, Kanagaratnam, P, Katus, H, Kautzner, J, Kriebel, T, Lancellotti, P, Landmesser, U, Leclercq, C, Lewis, B, Lopatin, Y, Merkely, B, Paul, T, Pavlovic, N, Petersen, S, Petronio, A, Potpara, T, Roffi, M, Scherr, D, Shlyakhto, E, Simpson, I, Zeppenfeld, K, Windecker, S, Baigent, C, Collet, J, Dean, V, Gale, C, Grobbee, D, Halvorsen, S, Iung, B, Juni, P, Lettino, M, Mueller, C, Richter, D, Sousa-Uva, M, Touyz, R, Amara, W, Grigoryan, S, Podczeck-Schweighofer, A, Chasnoits, A, Vandekerckhove, Y, Sokolovich, S, Traykov, V, Skoric, B, Papasavvas, E, Riahi, S, Kampus, P, Parikka, H, Piot, O, Etsadashvili, K, Stellbrink, C, Manolis, A, Csanadi, Z, Gudmundsson, K, Erwin, J, Barsheshet, A, De Ponti, R, Abdrakhmanov, A, Jashari, H, Lunegova, O, Jubele, K, Refaat, M, Puodziukynas, A, Groben, L, Grosu, A, Ibtissam, F, Trines, S, Poposka, L, Haugaa, K, Kowalski, O, Cavaco, D, Dobreanu, D, Mikhaylov, E, Zavatta, M, Nebojsa, M, Ferreira-Gonzalez, I, Juhlin, T, Reichlin, T, Haouala, H, Akgun, T, Gupta, D, Brugada J., Katritsis D. G., Arbelo E., Arribas F., Bax J. J., Blomstrom-Lundqvist C., Calkins H., Corrado D., Deftereos S. G., Diller G. -P., Gomez-Doblas J. J., Gorenek B., Grace A., Ho S. Y., Kaski J. -C., Kuck K. -H., Lambiase P. D., Sacher F., Sarquella-Brugada G., Suwalski P., Zaza A., De Potter T., Sticherling C., Aboyans V., Basso C., Bocchiardo M., Budts W., Delgado V., Dobrev D., Fitzsimons D., Gevaert S., Heidbuchel H., Hindricks G., Hlivak P., Kanagaratnam P., Katus H., Kautzner J., Kriebel T., Lancellotti P., Landmesser U., Leclercq C., Lewis B., Lopatin Y., Merkely B., Paul T., Pavlovic N., Petersen S., Petronio A. S., Potpara T., Roffi M., Scherr D., Shlyakhto E., Simpson I. A., Zeppenfeld K., Windecker S., Baigent C., Collet J. -P., Dean V., Gale C. P., Grobbee D. E., Halvorsen S., Iung B., Juni P., Lettino M., Mueller C., Richter D. J., Sousa-Uva M., Touyz R. M., Amara W., Grigoryan S., Podczeck-Schweighofer A., Chasnoits A., Vandekerckhove Y., Sokolovich S., Traykov V., Skoric B., Papasavvas E., Riahi S., Kampus P., Parikka H., Piot O., Etsadashvili K., Stellbrink C., Manolis A. S., Csanadi Z., Gudmundsson K., Erwin J., Barsheshet A., De Ponti R., Abdrakhmanov A., Jashari H., Lunegova O., Jubele K., Refaat M. M., Puodziukynas A., Groben L., Grosu A., Ibtissam F., Trines S. A., Poposka L., Haugaa K. H., Kowalski O., Cavaco D., Dobreanu D., Mikhaylov E. N., Zavatta M., Nebojsa M., Ferreira-Gonzalez I., Juhlin T., Reichlin T., Haouala H., Akgun T., and Gupta D.

Abstract

E' una "linea-guida" non esiste abstract.

Published
2020

48. European Society of Cardiology guidance for the diagnosis and management of cardiovascular disease during the COVID-19 pandemic: part 1—epidemiology, pathophysiology, and diagnosis

Author

Baigent, C., Windecker, S., Andreini, D., Arbelo, E., Barbato, E., Bartorelli, A.L., Baumbach, A., Behr, E.R., Berti, S., Bueno, H., Capodanno, D., Cappato, R., Chieffo, A., Collet, J.P., Cuisset, T., Simone, G. de, Delgado, V., Dendale, P., Dudek, D., Edvardsen, T., Elvan, A., Gonzalez-Juanatey, J.R., Gori, M., Grobbee, D., Guzik, T.J., Halvorsen, S., Haude, M., Heidbuchel, H., Hindricks, G., Ibanez, B., Karam, N., Katus, H., Klok, F.A., Konstantinides, S.V., Landmesser, U., Leclercq, C., Leonardi, S., Lettino, M., Marenzi, G., Mauri, J., Metra, M., Morici, N., Mueller, C., Petronio, A.S., Polovina, M.M., Potpara, T., Praz, F., Prendergast, B., Prescott, E., Price, S., Pruszczyk, P., Rodriguez-Leor, O., Roffi, M., Romaguera, R., Rosenkranz, S., Sarkozy, A., Scherrenberg, M., Seferovic, P., Senni, M., Spera, F.R., Stefanini, G., Thiele, H., Tomasoni, D., Torracca, L., Touyz, R.M., Wilde, A.A., Williams, B., Task Force Management Covid-19 Eur, Nuffield Department of Population Health [Oxford], University of Oxford, Bern University Hospital [Berne] (Inselspital), CHU Pitié-Salpêtrière [AP-HP], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Sorbonne Université (SU), Nutrition, obésité et risque thrombotique (NORT), Institut National de la Recherche Agronomique (INRA)-Aix Marseille Université (AMU)-Institut National de la Santé et de la Recherche Médicale (INSERM), Paris-Centre de Recherche Cardiovasculaire (PARCC (UMR_S 970/ U970)), Hôpital Européen Georges Pompidou [APHP] (HEGP), Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Hôpitaux Universitaires Paris Ouest - Hôpitaux Universitaires Île de France Ouest (HUPO)-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Hôpitaux Universitaires Paris Ouest - Hôpitaux Universitaires Île de France Ouest (HUPO)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Paris Cité (UPCité), CHU Pontchaillou [Rennes], Laboratoire Traitement du Signal et de l'Image (LTSI), Université de Rennes (UR)-Institut National de la Santé et de la Recherche Médicale (INSERM), University of Glasgow, Amsterdam UMC - Amsterdam University Medical Center, University College of London [London] (UCL), Baigent, C, Cardiology, Task Force for the management of COVID-19 of the European Society of, Cardiology, ACS - Heart failure & arrhythmias, Task Force Management Covid-19 Eur, University of Oxford [Oxford], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP), Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Hôpitaux Universitaires Paris Ouest - Hôpitaux Universitaires Île de France Ouest (HUPO)-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Hôpitaux Universitaires Paris Ouest - Hôpitaux Universitaires Île de France Ouest (HUPO)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Paris Cité (UPC), Université de Rennes 1 (UR1), Université de Rennes (UNIV-RENNES)-Université de Rennes (UNIV-RENNES)-Institut National de la Santé et de la Recherche Médicale (INSERM), delgado, victoria/0000-0002-9841-2737, BUENO, HECTOR/0000-0003-0277-7596, Karam, Nicole/0000-0002-3861-6914, Baigent, Colin/0000-0003-4856-7420, Behr, Elijah/0000-0002-8731-2853, Williams, Bryan/0000-0002-8094-1841, Rodriguez-Leor, Oriol/0000-0003-2657-5657, BUENO, HECTOR/0000-0003-0277-7596, Rodriguez-Leor, Oriol/0000-0003-2657-5657, Williams, Bryan/0000-0002-8094-1841, Karam, and Nicole/0000-0002-3861-6914

Subjects
ACE2, Arrhythmias, Biomarkers, Cardiogenic shock, COVID-19, Myocardial, medicine.medical_specialty, Coronavirus disease 2019 (COVID-19), Physiology, Myocardial injury, Myocarditis, Non-invasive imaging, Humans, Pandemics, Prospective Studies, Cardiology, Cardiovascular Diseases, Settore MED/11 - Malattie dell'Apparato Cardiovascolare, Disease, Special Article, [SDV.MHEP.CSC]Life Sciences [q-bio]/Human health and pathology/Cardiology and cardiovascular system, Physiology (medical), injury, Pandemic, Epidemiology, Medicine, AcademicSubjects/MED00200, Intensive care medicine, business.industry, Pathophysiology, Human medicine, Cardiology and Cardiovascular Medicine, business
Abstract

Aims Since its emergence in early 2020, the novel severe acute respiratory syndrome coronavirus 2 causing coronavirus disease 2019 (COVID-19) has reached pandemic levels, and there have been repeated outbreaks across the globe. The aim of this two-part series is to provide practical knowledge and guidance to aid clinicians in the diagnosis and management of cardiovascular disease (CVD) in association with COVID-19. Methods and results A narrative literature review of the available evidence has been performed, and the resulting information has been organized into two parts. The first, reported here, focuses on the epidemiology, pathophysiology, and diagnosis of cardiovascular (CV) conditions that may be manifest in patients with COVID-19. The second part, which will follow in a later edition of the journal, addresses the topics of care pathways, treatment, and follow-up of CV conditions in patients with COVID-19. Conclusion This comprehensive review is not a formal guideline but rather a document that provides a summary of current knowledge and guidance to practicing clinicians managing patients with CVD and COVID-19. The recommendations are mainly the result of observations and personal experience from healthcare providers. Therefore, the information provided here may be subject to change with increasing knowledge, evidence from prospective studies, and changes in the pandemic. Likewise, the guidance provided in the document should not interfere with recommendations provided by local and national healthcare authorities., Graphical Abstract Graphical Abstract

Published
2022
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49. Device runtime and costs of cardiac resynchronization therapy pacemakers - a health claims data analysis

Author

Hadwiger, M, Dagres, N, Hindricks, G, L'hoest, H, Marschall, U, Katalinic, A, Frielitz, FS, Hadwiger, M, Dagres, N, Hindricks, G, L'hoest, H, Marschall, U, Katalinic, A, and Frielitz, FS

Abstract

Introduction: This study investigates the runtime and costs of biventricular defibrillators (CRT-D) and biventricular pacemakers (CRT-P). Accurate estimates of cardiac resynchronization therapy (CRT) device runtime across all manufactures are rare, especially for CRT-P.Methods: Health claims data of a large nationwide German health insurance was used to analyze CRT device runtime. We defined device runtime as the time between the date of implantation and the date of generator change or removal. The median costs for implantation, change, and removal of a CRT device were calculated accordingly.Results: In total, the data set comprises 17,826 patients. A total of 4,296 complete runtimes for CRT-D devices and 429 complete runtimes for CRT-P devices were observed. Median device runtime was 6.04 years for CRT-D devices and 8.16 years for CRT-P devices (log-rank test p<0.0001). The median cost of implantation for a CRT-D device was 14,270 EUR, and for a CRT-P device 9,349 EUR.Conclusions: Compared to CRT-P devices, CRT-D devices had a significantly shorter device runtime of about two years. Moreover, CRT-D devices were associated with higher cost. The study provides important findings that can be utilized by cost-effectiveness analyses., Einleitung: Diese Studie untersucht die Laufzeit und Kosten von biventrikulären Defibrillatoren (CRT-D) und biventrikulären Schrittmachern (CRT-P). Genaue Schätzungen der Laufzeit von Geräten für die kardiale Resynchronisationstherapie (CRT) über alle Hersteller sind selten, insbesondere für CRT-P.Methoden: Zur Analyse der CRT-Gerätelaufzeit wurden Routinedaten einer großen bundesweiten deutschen Krankenkasse verwendet. Wir definierten die Gerätelaufzeit als die Zeit zwischen dem Datum der Implantation und dem Datum des Generatorwechsels oder der Entfernung. Die medianen Kosten für Implantation, Wechsel und Entfernung eines CRT-Gerätes wurden ebenfalls berechnet.Ergebnisse: Insgesamt umfasst der Datensatz 17.826 Patienten. Es wurden insgesamt 4.296 komplette Laufzeiten für CRT-D-Geräte und 429 komplette Laufzeiten für CRT-P-Geräte beobachtet. Die mediane Geräte-Laufzeit betrug 6,04 Jahre für CRT-D-Geräte und 8,16 Jahre für CRT-P-Geräte (Log-Rank-Test p<0,0001). Die medianen Implantationskosten betrugen 14.270 EUR für ein CRT-D-Gerät und 9.349 EUR für ein CRT-P-Gerät.Fazit: Im Vergleich zu CRT-P-Geräten hatten CRT-D-Geräte eine signifikant kürzere Gerätelaufzeit von etwa zwei Jahren. Außerdem waren CRT-D-Geräte mit höheren Kosten verbunden. Die Studie liefert wichtige Ergebnisse, die in Kosten-Effektivitätsanalysen verwendet werden können.

Published
2022

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