930 results on '"Hilberg, Ole"'
Search Results
2. Pulmonologists-Level lung cancer detection based on standard blood test results and smoking status using an explainable machine learning approach
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Flyckt, Ricco Noel Hansen, Sjodsholm, Louise, Henriksen, Margrethe Høstgaard Bang, Brasen, Claus Lohman, Ebrahimi, Ali, Hilberg, Ole, Hansen, Torben Frøstrup, Wiil, Uffe Kock, Jensen, Lars Henrik, and Peimankar, Abdolrahman
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Computer Science - Machine Learning - Abstract
Lung cancer (LC) remains the primary cause of cancer-related mortality, largely due to late-stage diagnoses. Effective strategies for early detection are therefore of paramount importance. In recent years, machine learning (ML) has demonstrated considerable potential in healthcare by facilitating the detection of various diseases. In this retrospective development and validation study, we developed an ML model based on dynamic ensemble selection (DES) for LC detection. The model leverages standard blood sample analysis and smoking history data from a large population at risk in Denmark. The study includes all patients examined on suspicion of LC in the Region of Southern Denmark from 2009 to 2018. We validated and compared the predictions by the DES model with diagnoses provided by five pulmonologists. Among the 38,944 patients, 9,940 had complete data of which 2,505 (25\%) had LC. The DES model achieved an area under the roc curve of 0.77$\pm$0.01, sensitivity of 76.2\%$\pm$2.4\%, specificity of 63.8\%$\pm$2.3\%, positive predictive value of 41.6\%$\pm$1.2\%, and F\textsubscript{1}-score of 53.8\%$\pm$1.1\%. The DES model outperformed all five pulmonologists, achieving a sensitivity 9\% higher than their average. The model identified smoking status, age, total calcium levels, neutrophil count, and lactate dehydrogenase as the most important factors for the detection of LC. The results highlight the successful application of the ML approach in detecting LC, surpassing pulmonologists' performance. Incorporating clinical and laboratory data in future risk assessment models can improve decision-making and facilitate timely referrals., Comment: 9 pages, 4 figures
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- 2024
3. Telephone follow-up as a substitute for standard out-clinic follow-up in CPAP therapy for obstructive sleep apnea patients: a randomized controlled trial
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Wolsing, Sofie Krogh, Frølund, Jannie Christina, Dalgård, Christine, Hilberg, Ole, and Gantzhorn, Eline
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- 2024
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4. FDG-PET/CT-based respiration-gated lung segmentation and quantification of lung inflammation in COPD patients
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Dogan, Ayse Dudu Altintas, Christensen, Thomas Quist, Jensen, Torben Tranborg, Juhl, Claus Bogh, Hilberg, Ole, Bladbjerg, Else-Marie, and Hess, Søren
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- 2024
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5. Identification of patients’ smoking status using an explainable AI approach: a Danish electronic health records case study
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Ebrahimi, Ali, Henriksen, Margrethe Bang Høstgaard, Brasen, Claus Lohman, Hilberg, Ole, Hansen, Torben Frøstrup, Jensen, Lars Henrik, Peimankar, Abdolrahman, and Wiil, Uffe Kock
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- 2024
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6. Description of an activity-based enzyme biosensor for lung cancer detection
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Dempsey, Paul W., Sandu, Cristina-Mihaela, Gonzalezirias, Ricardo, Hantula, Spencer, Covarrubias-Zambrano, Obdulia, Bossmann, Stefan H., Nagji, Alykhan S., Veeramachaneni, Nirmal K., Ermerak, Nezih O., Kocakaya, Derya, Lacin, Tunc, Yildizeli, Bedrittin, Lilley, Patrick, Wen, Sara W. C., Nederby, Line, Hansen, Torben F., and Hilberg, Ole
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- 2024
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7. Burden of Disease and Productivity Loss in the European Economic Area in Patients Affected by Fibrosing Interstitial Lung Disease
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Løkke, Anders, Castello, Luca, Pinheiro Martins, Pedro, Soulard, Stéphane, and Hilberg, Ole
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- 2023
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8. Urban-rural and socio-economic differences in inhaled corticosteroid treatment for chronic obstructive pulmonary disease: A nationwide register-based cross-sectional study
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Klitgaard, Allan, Ibsen, Rikke, Hilberg, Ole, and Løkke, Anders
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- 2024
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9. Nationwide Increasing Incidence of Nontuberculous Mycobacterial Diseases Among Adults in Denmark: Eighteen Years of Follow-Up
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Pedersen, Andreas A., Løkke, Anders, Fløe, Andreas, Ibsen, Rikke, Johansen, Isik S., and Hilberg, Ole
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- 2024
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10. New insights in the genetic variant spectrum of SLC34A2 in pulmonary alveolar microlithiasis; a systematic review
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Jönsson, Åsa Lina M., Hilberg, Ole, Simonsen, Ulf, Christensen, Jane Hvarregaard, and Bendstrup, Elisabeth
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- 2023
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11. NK cell activity and methylated HOXA9 ctDNA as prognostic biomarkers in patients with non-small cell lung cancer treated with PD-1/PD-L1 inhibitors
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Wen, Sara Witting Christensen, Nederby, Line, Andersen, Rikke Fredslund, Hansen, Torben Schjødt, Nyhus, Christa Haugaard, Hilberg, Ole, Jakobsen, Anders, and Hansen, Torben Frøstrup
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- 2023
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12. The Danish lung cancer registry: A nationwide validation study
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Gouliaev, Anja, Ali, Fatima, Jakobsen, Erik, Dalton, Susanne O., Hilberg, Ole, Rasmussen, Torben R., and Christensen, Niels L.
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- 2024
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13. Introduction of the Danish Lung Nodule Registry: A part of the Danish Lung Cancer Registry
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Borg, Morten, Rasmussen, Torben Riis, and Hilberg, Ole
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- 2024
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14. Burden of Uncontrolled Severe Asthma With and Without Elevated Type-2 Inflammatory Biomarkers
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del Olmo, Ricardo, Anderson, Gary, Reddel, Helen, Rabahi, Marcelo, McIvor, Andrew, Sadatsafavi, Mohsen, Weinreich, Ulla, Burgel, Pierre-Régis, Devouassoux, Gilles, Papi, Alberto, Inoue, Hiromasa, Rendon, Adrián, van den Berge, Maarten, Beasley, Richard, García-Navarro, Alvar Agusti, Faner, Rosa, Rivera, José Olaguibel, Janson, Christer, Bilińska-Izydorczyk, Magdalena, Fagerås, Malin, Fihn-Wikander, Titti, Franzén, Stefan, Keen, Christina, Ostridge, Kristoffer, Chalmers, James, Harrison, Timothy, Pavord, Ian, Price, David, Azim, Adnan, Belton, Laura, Blé, Francois-Xavier, Erhard, Clement, Gairy, Kerry, Hughes, Rod, Lassi, Glenda, Müllerová, Hana, Rapsomaniki, Eleni, Scott, Ian Christopher, Chipps, Bradley, Christenson, Stephanie, Make, Barry, Tomaszewski, Erin, Benhabib, Gabriel, Ruiz, Xavier Bocca, Lisanti, Raul Eduardo, Marino, Gustavo, Mattarucco, Walter, Nogueira, Juan, Parody, Maria, Pascale, Pablo, Rodriguez, Pablo, Silva, Damian, Svetliza, Graciela, Victorio, Carlos F., Rolon, Roxana Willigs, Yañez, Anahi, Baines, Stuart, Bowler, Simon, Bremner, Peter, Bull, Sheetal, Carroll, Patrick, Chaalan, Mariam, Farah, Claude, Hammerschlag, Gary, Hancock, Kerry, Harrington, Zinta, Katsoulotos, Gregory, Kim, Joshua, Langton, David, Lee, Donald, Peters, Matthew, Prassad, Lakshman, Sajkov, Dimitar, Santiago, Francis, Simpson, Frederick Graham, Tai, Sze, Thomas, Paul, Wark, Peter, Delfini Cançado, José Eduardo, Cunha, Thúlio, Lima, Marina, Cardoso, Alexandre Pinto, FitzGerald, J. Mark, Anees, Syed, Bertley, John, Bell, Alan, Cheema, Amarjit, Chouinard, Guy, Csanadi, Michael, Dhar, Anil, Dhillon, Ripple, Kanawaty, David, Kelly, Allan, Killorn, William, Landry, Daniel, Luton, Robert, Mandhane, Piushkumar, Pek, Bonavuth, Petrella, Robert, Stollery, Daniel, Wang, Chen, Chen, Meihua, Chen, Yan, Gu, Wei, Christopher Hui, Kim Ming, Li, Manxiang, Li, Shiyue, Lijun, Ma, Qin, Guangyue, Song, Weidong, Tan, Wei, Tang, Yijun, Wang, Tan, Wen, Fuqiang, Wu, Feng, Xiang, PingChao, Xiao, Zuke, Xiong, Shengdao, Yang, Jinghua, Yang, Jingping, Zhang, Caiqing, Zhang, Min, Zhang, Ping, Zhang, Wei, Zheng, Xiaohe, Zhu, Dan, Bueno, Carlos Matiz, Grimaldos, Fabio Bolivar, Arboleda, Alejandra Cañas, Molina de Salazar, Dora, Bendstrup, Elisabeth, Hilberg, Ole, Kjellerup, Carsten, Raherison, Chantal, Bonniaud, Philippe, Brun, Olivier, Chouaid, Christos, Couturaud, Francis, de Blic, Jacques, Debieuvre, Didier, Delsart, Dominique, Demaegdt, Axelle, Demoly, Pascal, Deschildre, Antoine, Egron, Carole, Falchero, Lionel, Goupil, François, Kessler, Romain, Le Roux, Pascal, Mabire, Pascal, Mahay, Guillaume, Martinez, Stéphanie, Melloni, Boris, Moreau, Laurent, Riviere, Emilie, Roux-Claudé, Pauline, Soulier, Michel, Vignal, Guillaume, Yaici, Azzedine, Bals, Robert, Aries, Sven Philip, Beck, Ekkehard, Deimling, Andreas, Feimer, Jan, Grimm-Sachs, Vera, Groth, Gesine, Herth, Felix, Hoheisel, Gerhard, Kanniess, Frank, Lienert, Thomas, Mronga, Silke, Reinhardt, Jörg, Schlenska, Christian, Stolpe, Christoph, Teber, Ishak, Timmermann, Hartmut, Ulrich, Thomas, Velling, Peter, Wehgartner-Winkler, Sabina, Welling, Juergen, Winkelmann, Ernst-Joachim, Barbetta, Carlo, Braido, Fulvio, Cardaci, Vittorio, Clini, Enrico Maria, Costantino, Maria Teresa, Cuttitta, Giuseppina, di Gioacchino, Mario, Fois, Alessandro, Foschino-Barbaro, Maria Pia, Gammeri, Enrico, Inchingolo, Riccardo, Lavorini, Federico, Molino, Antonio, Nucera, Eleonora, Patella, Vincenzo, Pesci, Alberto, Ricciardolo, Fabio, Rogliani, Paola, Sarzani, Riccardo, Vancheri, Carlo, Vincenti, Rigoletta, Endo, Takeo, Fujita, Masaki, Hara, Yu, Horiguchi, Takahiko, Hosoi, Keita, Ide, Yumiko, Inomata, Minehiko, Inoue, Koji, Inoue, Sumito, Kato, Motokazu, Kawasaki, Masayuki, Kawayama, Tomotaka, Kita, Toshiyuki, Kobayashi, Kanako, Koto, Hiroshi, Nishi, Koichi, Saito, Junpei, Shimizu, Yasuo, Shirai, Toshihiro, Sugihara, Naruhiko, Takahashi, Ken-ichi, Tashimo, Hiroyuki, Tomii, Keisuke, Yamada, Takashi, Yanai, Masaru, Rendon, Adrian, Javier, Ruth Cerino, Peregrina, Alfredo Domínguez, Corzo, Marco Fernández, Gonzalez, Efraín Montano, Ramírez-Venegas, Alejandra, Boersma, Willem, Djamin, R.S., Eijsvogel, Michiel, Franssen, Frits, Goosens, Martijn, Graat-Verboom, Lidwien, Veen, Johannes in 't, Janssen, Rob, Kuppens, Kim, van de Ven, Mario, Bakke, Per, Brunstad, Ole Petter, Einvik, Gunnar, Høines, Kristian Jong, Khusrawi, Alamdar, Oien, Torbjorn, Yoon, Ho Joo, Chang, Yoon-Seok, Cho, Young Joo, Hwang, Yong Il, Kim, Woo Jin, Koh, Young-Il, Lee, Byung-Jae, Lee, Kwan-Ho, Lee, Sang-Pyo, Lee, Yong Chul, Lim, Seong Yong, Min, Kyung Hun, Oh, Yeon-Mok, Park, Choon-Sik, Park, Hae-Sim, Park, Heung-Woo, Rhee, Chin Kook, Yoon, Hyoung-Kyu, Andújar, Rubén, Anoro, Laura, García, María Buendía, Mozo, Paloma Campo, Campos, Sergio, Maldonado, Francisco Casas, Martínez, Manuel Castilla, Serrano, Carolina Cisneros, Casanova, Lorena Comeche, Corbacho, Dolores, Del Campo Matías, Felix, Echave-Sustaeta, Jose, Corral, Gloria Francisco, Setién, Pedro Gamboa, Clemente, Marta García, Núñez, Ignacio García, Robaina, Jose García, Salmones, Mercedes García, Marín Trigo, Jose Maria, Fernandez, Marta Nuñez, Palomo, Sara Nuñez, Pérez de Llano, Luis, Bastida, Ana Pueyo, Rañó, Ana, González-Moro, José Rodríguez, Reig, Albert Roger, Garrido, José Velasco, Curiac, Dan, Lif-Tiberg, Cornelia, Luts, Anders, Råhlen, Lennart, Rustscheff, Stefan, Adams, Frances, Bradman, Drew, Broughton, Emma, Cosgrove, John, Flood-Page, Patrick, Fuller, Elizabeth, Hartley, David, Hattotuwa, Keith, Jones, Gareth, Lewis, Keir, McGarvey, Lorcan, Morice, Alyn, Pandya, Preeti, Patel, Manish, Roy, Kay, Sathyamurthy, Ramamurthy, Thiagarajan, Swaminathan, Turner, Alice, Vestbo, Jorgen, Wedzicha, Wisia, Wilkinson, Tom, Wilson, Pete, Al-Asadi, Lo’Ay, Anholm, James, Averill, Francis, Bansal, Sandeep, Baptist, Alan, Campbell, Colin, Campos, Michael A., Crook, Gretchen, DeLeon, Samuel, Eid, Alain, Epstein, Ellen, Fritz, Stephen, Harris, Hoadley, Hewitt, Mitzie, Holguin, Fernando, Hudes, Golda, Jackson, Richard, Kaufman, Alan, Kaufman, David, Klapholz, Ari, Krishna, Harshavardhan, Lee, Daria, Lin, Robert, Maselli-Caceres, Diego, Mehta, Vinay, Moy, James N., Nwokoro, Ugo, Parikh, Purvi, Parikh, Sudhir, Perrino, Frank, Ruhlmann, James, Sassoon, Catherine, Settipane, Russell A., Sousa, Daniel, Sriram, Peruvemba, Wachs, Richard, Ding, Bo, Chen, Stephanie, Quinton, Anna, Cook, William, and Reddel, Helen K.
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- 2024
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15. Clinical Response and Remission in Patients With Severe Asthma Treated With Biologic Therapies
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Hansen, Susanne, Baastrup Søndergaard, Marianne, von Bülow, Anna, Bjerrum, Anne-Sofie, Schmid, Johannes, Rasmussen, Linda M., Johnsen, Claus R., Ingebrigtsen, Truls, Håkansson, Kjell Erik Julius, Johansson, Sofie Lock, Bisgaard, Maria, Assing, Karin Dahl, Hilberg, Ole, Ulrik, Charlotte, and Porsbjerg, Celeste
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- 2024
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16. Tobacco Exposure and Efficacy of Biologic Therapy in Patients With Severe Asthma: A Nationwide Study From the Danish Severe Asthma Register
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Baastrup Soendergaard, Marianne, Hansen, Susanne, Bjerrum, Anne-Sofie, von Bülow, Anna, Haakansson, Kjell Erik Julius, Hilberg, Ole, Ingebrigtsen, Truls Sylvan, Johnsen, Claus Rikard, Lock-Johansson, Sofie, Makowska Rasmussen, Linda, Schmid, Johannes Martin, Ulrik, Charlotte Suppli, and Porsbjerg, Celeste
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- 2024
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17. Fatigue in Patients with Sarcoidosis in Denmark
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Møller, Janne, Hilberg, Ole, and Bendstrup, Elisabeth
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Medical research ,Medicine, Experimental ,Fatigue -- Development and progression -- Risk factors -- Care and treatment ,Health - Abstract
Introduction Sarcoidosis is a systemic granulomatous disease of unknown etiology, primarily affecting the lungs and thoracic lymph nodes. Fatigue is a frequent and disabling symptom in sarcoidosis with a significant impact on quality of life. In Denmark, the incidence of sarcoidosis has increased; however, the extent and risk factors of fatigue have not been investigated and no recent reports of the characteristics of patients with sarcoidosis in Denmark exist. Aim To assess the frequency of fatigue in patients with sarcoidosis in Denmark at diagnosis and to investigate if fatigue correlated with relevant disease parameters. Moreover, to characterize patients with sarcoidosis in Denmark at time of diagnosis. Methods Data were collected in 150 patients with recently diagnosed sarcoidosis. Fatigue was measured using the Fatigue Assessment Scale (FAS). Patients with fatigue were compared to non-fatigue patients regarding clinical parameters. Results FAS was completed by 145 of 150 patients. Fifty-one percent reported significant fatigue. Mean FAS score was 23.6 and 51% had a FAS score [greater than or equal to] 22. Fatigue in 89 incident patients did not correlate significantly with demographics, physiological, or clinical parameters. Fifty-nine percent were males. Mean age was 47 years; mean values (% predicted) for pulmonary function tests were normal and 71% at Scadding stage 0-I. Conclusion In Denmark, fatigue was frequent in patients with sarcoidosis. The majority of patients had mild disease at diagnosis and were older but lower at Scadding stage at diagnosis compared to previous cohorts., Author(s): Janne Møller [sup.1], Ole Hilberg [sup.2], Elisabeth Bendstrup [sup.1] Author Affiliations: (1) grid.154185.c, 0000 0004 0512 597X, Department of Respiratory Diseases and Allergy, Centre for Rare Lung Diseases, Aarhus [...]
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- 2023
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18. Impact of Initiating Biologics in Patients With Severe Asthma on Long-Term Oral Corticosteroids or Frequent Rescue Steroids (GLITTER): Data From the International Severe Asthma Registry
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Chen, Wenjia, Tran, Trung N., Sadatsafavi, Mohsen, Murray, Ruth, Wong, Nigel Chong Boon, Ali, Nasloon, Ariti, Con, Bulathsinhala, Lakmini, Gil, Esther Garcia, FitzGerald, J. Mark, Alacqua, Marianna, Al-Ahmad, Mona, Altraja, Alan, Al-Lehebi, Riyad, Bhutani, Mohit, Bjermer, Leif, Bjerrum, Anne-Sofie, Bourdin, Arnaud, von Bülow, Anna, Busby, John, Canonica, Giorgio Walter, Carter, Victoria, Christoff, George C., Cosio, Borja G., Costello, Richard W., Fonseca, João A., Gibson, Peter G., Yoo, Kwang-Ha, Heaney, Liam G., Heffler, Enrico, Hew, Mark, Hilberg, Ole, Hoyte, Flavia, Iwanaga, Takashi, Jackson, David J., Jones, Rupert C., Koh, Mariko Siyue, Kuna, Piotr, Larenas-Linnemann, Désirée, Lehmann, Sverre, Lehtimäki, Lauri, Lyu, Juntao, Mahboub, Bassam, Maspero, Jorge, Menzies-Gow, Andrew N., Newell, Anthony, Sirena, Concetta, Papadopoulos, Nikolaos G., Papaioannou, Andriana I., Perez-de-Llano, Luis, Perng (Steve), Diahn-Warng, Peters, Matthew, Pfeffer, Paul E., Porsbjerg, Celeste M., Popov, Todor A., Rhee, Chin Kook, Salvi, Sundeep, Taillé, Camille, Taube, Christian, Torres-Duque, Carlos A., Ulrik, Charlotte, Ra, Seung-Won, Wang, Eileen, Wechsler, Michael E., and Price, David B.
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- 2023
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19. Cluster Analyses From the Real-World NOVELTY Study: Six Clusters Across the Asthma-COPD Spectrum
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Olmo, Ricardo del, Anderson, Gary, Reddel, Helen, Rabahi, Marcelo, McIvor, Andrew, Sadatsafavi, Mohsen, Weinreich, Ulla, Burgel, Pierre-Régis, Devouassoux, Gilles, Papi, Alberto, Inoue, Hiromasa, Rendon, Adrián, van den Berge, Maarten, Beasley, Richard, García-Navarro, Alvar Agusti, Faner, Rosa, Olaguibel Rivera, José, Janson, Christer, Bilińska-Izydorczyk, Magdalena, Fagerås, Malin, Fihn-Wikander, Titti, Franzén, Stefan, Keen, Christina, Ostridge, Kristoffer, Chalmers, James, Harrison, Timothy, Pavord, Ian, Price, David, Azim, Adnan, Belton, Laura, Blé, Francois-Xavier, Erhard, Clement, Gairy, Kerry, Hughes, Rod, Lassi, Glenda, Müllerová, Hana, Rapsomaniki, Eleni, Scott, Ian Christopher, Chipps, Bradley, Christenson, Stephanie, Make, Barry, Tomaszewski, Erin, Benhabib, Gabriel, Ruiz, Xavier Bocca, Lisanti, Raul Eduardo, Marino, Gustavo, Mattarucco, Walter, Nogueira, Juan, Parody, Maria, Pascale, Pablo, Rodriguez, Pablo, Silva, Damian, Svetliza, Graciela, Victorio, Carlos F., Rolon, Roxana Willigs, Yañez, Anahi, Baines, Stuart, Bowler, Simon, Bremner, Peter, Bull, Sheetal, Carroll, Patrick, Chaalan, Mariam, Farah, Claude, Hammerschlag, Gary, Hancock, Kerry, Harrington, Zinta, Katsoulotos, Gregory, Kim, Joshua, Langton, David, Lee, Donald, Peters, Matthew, Prassad, Lakshman, Sajkov, Dimitar, Santiago, Francis, Simpson, Frederick Graham, Tai, Sze, Thomas, Paul, Wark, Peter, Cançado, José Eduardo Delfini, Cunha, Thúlio, Lima, Marina, Cardoso, Alexandre Pinto, FitzGerald, J. Mark, Anees, Syed, Bertley, John, Bell, Alan, Cheema, Amarjit, Chouinard, Guy, Csanadi, Michael, Dhar, Anil, Dhillon, Ripple, Kanawaty, David, Kelly, Allan, Killorn, William, Landry, Daniel, Luton, Robert, Mandhane, Piushkumar, Pek, Bonavuth, Petrella, Robert, Stollery, Daniel, Wang, Chen, Chen, Meihua, Chen, Yan, Gu, Wei, Christopher Hui, Kim Ming, Li, Manxiang, Li, Shiyue, Lijun, Ma, Qin, Guangyue, Song, Weidong, Tan, Wei, Tang, Yijun, Wang, Tan, Wen, Fuqiang, Wu, Feng, Xiang, PingChao, Xiao, Zuke, Xiong, Shengdao, Yang, Jinghua, Yang, Jingping, Zhang, Caiqing, Zhang, Min, Zhang, Ping, Zhang, Wei, Zheng, Xiaohe, Zhu, Dan, Bueno, Carlos Matiz, Grimaldos, Fabio Bolivar, Arboleda, Alejandra Cañas, de Salazar, Dora Molina, Bendstrup, Elisabeth, Hilberg, Ole, Kjellerup, Carsten, Raherison, Chantal, Bonniaud, Philippe, Brun, Olivier, Chouaid, Christos, Couturaud, Francis, de Blic, Jacques, Debieuvre, Didier, Delsart, Dominique, Demaegdt, Axelle, Demoly, Pascal, Deschildre, Antoine, Egron, Carole, Falchero, Lionel, Goupil, François, Kessler, Romain, Le Roux, Pascal, Mabire, Pascal, Mahay, Guillaume, Martinez, Stéphanie, Melloni, Boris, Moreau, Laurent, Riviere, Emilie, Roux-Claudé, Pauline, Soulier, Michel, Vignal, Guillaume, Yaici, Azzedine, Bals, Robert, Aries, Sven Philip, Beck, Ekkehard, Deimling, Andreas, Feimer, Jan, Grimm-Sachs, Vera, Groth, Gesine, Herth, Felix, Hoheisel, Gerhard, Kanniess, Frank, Lienert, Thomas, Mronga, Silke, Reinhardt, Jörg, Schlenska, Christian, Stolpe, Christoph, Teber, Ishak, Timmermann, Hartmut, Ulrich, Thomas, Velling, Peter, Wehgartner-Winkler, Sabina, Welling, Juergen, Winkelmann, Ernst-Joachim, Barbetta, Carlo, Braido, Fulvio, Cardaci, Vittorio, Clini, Enrico Maria, Costantino, Maria Teresa, Cuttitta, Giuseppina, di Gioacchino, Mario, Fois, Alessandro, Foschino-Barbaro, Maria Pia, Gammeri, Enrico, Inchingolo, Riccardo, Lavorini, Federico, Molino, Antonio, Nucera, Eleonora, Patella, Vincenzo, Pesci, Alberto, Ricciardolo, Fabio, Rogliani, Paola, Sarzani, Riccardo, Vancheri, Carlo, Vincenti, Rigoletta, Endo, Takeo, Fujita, Masaki, Hara, Yu, Horiguchi, Takahiko, Hosoi, Keita, Ide, Yumiko, Inomata, Minehiko, Inoue, Koji, Inoue, Sumito, Kato, Motokazu, Kawasaki, Masayuki, Kawayama, Tomotaka, Kita, Toshiyuki, Kobayashi, Kanako, Koto, Hiroshi, Nishi, Koichi, Saito, Junpei, Shimizu, Yasuo, Shirai, Toshihiro, Sugihara, Naruhiko, Takahashi, Ken-ichi, Tashimo, Hiroyuki, Tomii, Keisuke, Yamada, Takashi, Yanai, Masaru, Rendon, Adrian, Cerino Javier, Ruth, Domínguez Peregrina, Alfredo, Fernández Corzo, Marco, Montano Gonzalez, Efraín, Ramírez-Venegas, Alejandra, Boersma, Willem, Djamin, R.S., Eijsvogel, Michiel, Franssen, Frits, Goosens, Martijn, Graat-Verboom, Lidwien, Veen, Johannes in 't, Janssen, Rob, Kuppens, Kim, van de Ven, Mario, Bakke, Per, Brunstad, Ole Petter, Einvik, Gunnar, Høines, Kristian Jong, Khusrawi, Alamdar, Oien, Torbjorn, Yoon, Ho Joo, Chang, Yoon-Seok, Cho, Young Joo, Hwang, Yong Il, Kim, Woo Jin, Koh, Young-Il, Lee, Byung-Jae, Lee, Kwan-Ho, Lee, Sang-Pyo, Lee, Yong Chul, Lim, Seong Yong, Min, Kyung Hun, Oh, Yeon-Mok, Park, Choon-Sik, Park, Hae-Sim, Park, Heung-Woo, Rhee, Chin Kook, Yoon, Hyoung-Kyu, García-Navarro, Alvar Agustí, Andújar, Rubén, Anoro, Laura, Buendía García, María, Mozo, Paloma Campo, Campos, Sergio, Casas Maldonado, Francisco, Castilla Martínez, Manuel, Cisneros Serrano, Carolina, Comeche Casanova, Lorena, Corbacho, Dolores, Campo Matías, Felix Del, Echave-Sustaeta, Jose, Corral, Gloria Francisco, Gamboa Setién, Pedro, García Clemente, Marta, Núñez, Ignacio García, García Robaina, Jose, García Salmones, Mercedes, Marín Trigo, Jose Maria, Fernandez, Marta Nuñez, Palomo, Sara Nuñez, Pérez de Llano, Luis, Pueyo Bastida, Ana, Rañó, Ana, Rodríguez González-Moro, José, Reig, Albert Roger, Velasco Garrido, José, Curiac, Dan, Lif-Tiberg, Cornelia, Luts, Anders, Råhlen, Lennart, Rustscheff, Stefan, Adams, Frances, Bradman, Drew, Broughton, Emma, Cosgrove, John, Flood-Page, Patrick, Fuller, Elizabeth, Hartley, David, Hattotuwa, Keith, Jones, Gareth, Lewis, Keir, McGarvey, Lorcan, Morice, Alyn, Pandya, Preeti, Patel, Manish, Roy, Kay, Sathyamurthy, Ramamurthy, Thiagarajan, Swaminathan, Turner, Alice, Vestbo, Jørgen, Wedzicha, Wisia, Wilkinson, Tom, Wilson, Pete, Al-Asadi, Lo’Ay, Anholm, James, Averill, Francis, Bansal, Sandeep, Baptist, Alan, Campbell, Colin, Campos, Michael A., Crook, Gretchen, DeLeon, Samuel, Eid, Alain, Epstein, Ellen, Fritz, Stephen, Harris, Hoadley, Hewitt, Mitzie, Holguin, Fernando, Hudes, Golda, Jackson, Richard, Kaufman, Alan, Kaufman, David, Klapholz, Ari, Krishna, Harshavardhan, Lee, Daria, Lin, Robert, Maselli-Caceres, Diego, Mehta, Vinay, Moy, James N., Nwokoro, Ugo, Parikh, Purvi, Parikh, Sudhir, Perrino, Frank, Ruhlmann, James, Sassoon, Catherine, Settipane, Russell A., Sousa, Daniel, Sriram, Peruvemba, Wachs, Richard, Bansal, Aruna T., Agustí, Alvar, Fageras, Malin, Alacqua, Marianna, and Reddel, Helen K.
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- 2023
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20. Diagnosis and treatment of lung cancer in Denmark during the COVID-19 pandemic
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Olesen, Tina Bech, Rasmussen, Torben Riis, Jakobsen, Erik, Engberg, Henriette, Hilberg, Ole, Møller, Henrik, Jensen, Jens Winther, and Jensen, Henry
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- 2023
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21. A serologically assessed neo-epitope biomarker of cellular fibronectin degradation is related to pulmonary fibrosis
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Hansen, Annika Hummersgaard, Breisnes, Helene Wallem, Prior, Thomas Skovhus, Hilberg, Ole, Rasmussen, Daniel Guldager Kring, Genovese, Federica, Lukassen, Marie Vestergaard, Svensson, Birte, Langholm, Lasse Løcke, Manon-Jensen, Tina, Karsdal, Morten Asser, Leeming, Diana Julie, Bendstrup, Elisabeth, and Sand, Jannie Marie Bülow
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- 2023
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22. Severe Asthma Standard-of-Care Background Medication Reduction With Benralizumab: ANDHI in Practice Substudy
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Pohl, Wolfgang, Doberer, Daniel, Martinot, Jean Benoit, Deschampheleire, Maud, Himpe, Ulrike, Chapman, Kenneth, Cheema, Amarjit, Dorscheid, Delbert, Ramsey, Clare, Rolf, Jeffrey, Walker, Brandie, Olivenstein, Ronald, Poirier, Claude, Larivee, Pierre, Bjerrum, Anne Sofie, Titlestad, Ingrid, Hilberg, Ole, Kilpeläinen, Maritta, Bonniaud, Philippe, Taillé, Camille, Tiotiu, Iuliana-Angelica, Girodet, Pierre-Olivier, Blanc, François-Xavier, Pradelli, Johana, Didier, Alain, Nocent Ejnaini, Cecilia, Deslee, Gaetan, Pison, Christophe, Douadi, Youcef, Mahay, Guillaume, Devouassoux, Gilles, Melloni, Boris, Roux, Pauline-Marie, Bourdin, Arnaud, Fry, Stephanie, Schaum, Thomas, Schulz, Christian, Skowasch, Dirk, Taube, Christian, Welte, Tobias, Gleiber, Wolfgang, Brehler, Randolf, Schreiber, Jens, Schuette, Wolfgang, Kronsbein, Juliane, Bonnet, Reiner, Beck, Ekkehard, Lacedonia, Donato, Senna, Gianenrico, Caruso, Cristiano, Crimi, Nunzio, Blasi, Francesco, Santus, Pierachille, Canonica, Giorgio Walter, Guarnieri, Gabriella, Pelaia, Girolamo, Milanese, Manlio, Micheletto, Claudio, Corsico, Angelo Guido, Scichilone, Nicola, Spadaro, Giuseppe, Langeveld, Bas, Holters, Jurgen, Willem van den Berg, Jan, Smit, Arthur, Conemans, Lennart, van Veen, Helena, Staaks, Gerald, Lehmann, Sverre, Echave-Sustaeta, Jose Maria, Ribas, Christian Domingo, de Luiz Martinez, Gustavo, Gonzalez Perez, Ruperto, Garcia Rivero, Juan Luis, Gall, Xavier Muñoz, Soto Campos, Jose Gregorio, Mozo, Paloma Campo, Pan, Carmen Vidal, Fernandez, Ana Gomez-Bastero, Tellez, Sergio Campos, Rivera, Carlos Martinez, Bobolea, Irina Diana, Guerrero, Raquel Morillo, Garcia, Ismael Ali, Rodriguez Hermosa, Juan Luis, Stenfors, Nikolai, Tunsäter, Alf, Curiac, Dan, von Garnier, Christophe, Leuppi, Joerg, Schmid-Grendelmeier, Peter, Nasser, Shuaib, Chaudhuri, Rekha, Nordstrom, Monica, Saralaya, Dinesh, Pfeffer, Paul, Mansur, Adel, Short, Philip, Wenzel, Sally, Cherry, William Brett, Zafra, Heidi, Gonzalez, Erika, Soong, Weily, Davis, Benjamin, Kao, Neil, Hussain, Iftikhar, Maselli Caceres, Diego Jose, Harris, James, Calhoun, William, Rodicio, Ileana, Kaufman, David, Moss, Mark, Sztejman, Eric, DeLeon, Samuel, Sumino, Kaharu, Kashyap, Ravindra, Leflein, Jeffrey, Hajal, Rizan, Fakih, Faisal, Hill, David, Lin, Robert, Jarratt, Mikell, Subramaniam, Vijay, Sussman, Robert, Mumneh, Nayla, Reibman, Joan, Darveaux, Jared, Tan, Ricardo, Tanus, Tonny, Sikand, Vinay, Marshall, Gailen, Mehta, Hemalini, Cole, Jeremy, Goodman, Brad, Goss, Deborah, Bardelas, Jose, Milstone, Aaron, Mehta, Vinay, Clore, Lee, Millard, Mark, Palumbo, Michael, Puppala, Dileep, Leong, Mila, Prenner, Bruce, Robinette, Emory, Heidarian Raissy, Hengameh, Fost, David, Pleskow, Warren, Marcus, Michael, Ilowite, Jonathan, Moore, Wendy, Steven, Gary, De la Cruz, Luis, Chupp, Geoffrey, Berger, William, Randolph, Christopher, Holguin, Fernando, Kureishy, Shahrukh, Campbell, Edward, Peche, Rudi, Pini, Laura, Papi, Alberto, Beghé, Bianca, Peveri, Silvia, Henriquez Santa, Aythamy, Ramos Gonzalez, Jacinto, Vinge, Ines, St. John, Roy, Louis, Renaud, Harrison, Tim W., Chanez, Pascal, Menzella, Francesco, Philteos, George, Cosio, Borja G., Lugogo, Njira L., de Luiz, Gustavo, Burden, Annie, Adlington, Timothy, Keeling, Nanna, Kwiatek, Justin, and Garcia Gil, Esther
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- 2023
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23. Whole-blood culture-derived cytokine combinations for the diagnosis of tuberculosis
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Østergaard, Anne Ahrens, primary, Feddersen, Søren, additional, Barnkob, Mike B., additional, Lynggaard, Rasmus Bank, additional, Karstoft, Amanda Cecilie Annie, additional, Borup, Maria, additional, Titlestad, Ingrid Louise, additional, Jensen, Torben Tranborg, additional, Hilberg, Ole, additional, Wejse, Christian, additional, Bjerrum, Stephanie, additional, Blaabjerg, Morten, additional, Assing, Kristian, additional, and Johansen, Isik Somuncu, additional
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- 2024
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24. Longitudinal validation of King's Sarcoidosis Questionnaire in a prospective cohort with mild sarcoidosis
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Møller, Janne, primary, Prior, Thomas Skovhus, additional, Hilberg, Ole, additional, Birring, Surinder, additional, and Bendstrup, Elisabeth, additional
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- 2024
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25. OPTIMAL: Titration of anti-IL5 biologics in severe asthma - An open label randomised controlled trial
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Soendergaard, Marianne Baastrup, primary, Bjerrum, Anne-Sofie, additional, Rasmussen, Linda Makowska, additional, Lock-Johansson, Sofie, additional, Hilberg, Ole, additional, Hansen, Susanne, additional, von Bulow, Anna, additional, and Porsbjerg, Celeste, additional
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- 2024
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26. A cohort study of the long-term outcome of latent tuberculosis infection among socially marginalized people in a low-incidence country
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Stærke, Nina Breinholt, Martinsen, Janne Tegder, Jensen, Torben Tranborg, Weinreich, Ulla Møller, Hilberg, Ole, Folkvardsen, Dorte Bek, Wejse, Christian, and Fløe, Andreas
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- 2022
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27. The burden of mild asthma: Clinical burden and healthcare resource utilisation in the NOVELTY study
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Benhabib, Gabriel, Mandhane, Piushkumar, Ruiz, Xavier Bocca, McIvor, Andrew, Olmo, Ricardo del, Pek, Bonavuth, Lisanti, Raul Eduardo, Petrella, Robert, Marino, Gustavo, Stollery, Daniel, Mattarucco, Walter, Chen, Meihua, Nogueira, Juan, Chen, Yan, Parody, Maria, Gu, Wei, Pascale, Pablo, Hui, Kim Ming Christopher, Rodriguez, Pablo, Li, Manxiang, Silva, Damian, Li, Shiyue, Svetliza, Graciela, Ma, Lijun, Victorio, Carlos F., Qin, Guangyue, Rolon, Roxana Willigs, Song, Weidong, Yañez, Anahi, Tan, Wei, Baines, Stuart, Tang, Yijun, Bowler, Simon, Wang, Chen, Bremner, Peter, Wang, Tan, Bull, Sheetal, Wen, Fuqiang, Carroll, Patrick, Wu, Feng, Chaalan, Mariam, Xiang, PingChao, Farah, Claude, Xiao, Zuke, Hammerschlag, Gary, Xiong, Shengdao, Hancock, Kerry, Yang, Jinghua, Harrington, Zinta, Yang, Jingping, Katsoulotos, Gregory, Zhang, Caiqing, Kim, Joshua, Zhang, Min, Langton, David, Zhang, Ping, Lee, Donald, Zhang, Wei, Peters, Matthew, Zheng, Xiaohe, Prassad, Lakshman, Zhu, Dan, Reddel, Helen, Bolivar Grimaldos, Fabio, Sajkov, Dimitar, Arboleda, Alejandra Cañas, Santiago, Francis, Bueno, Carlos Matiz, Simpson, Frederick Graham, Molina de Salazar, Dora, Tai, Sze, Bendstrup, Elisabeth, Thomas, Paul, Hilberg, Ole, Wark, Peter, Kjellerup, Carsten, Cançado, José Eduardo Delfini, Weinreich, Ulla, Cunha, Thúlio, Bonniaud, Philippe, Lima, Marina, Brun, Olivier, Cardoso, Alexandre Pinto, Burgel, Pierre-Régis, Rabahi, Marcelo, Chouaid, Christos, Anees, Syed, Couturaud, Francis, Bertley, John, de Blic, Jacques, Bell, Alan, Debieuvre, Didier, Cheema, Amarjit, Delsart, Dominique, Chouinard, Guy, Demaegdt, Axelle, Csanadi, Michael, Demoly, Pascal, Dhar, Anil, Deschildre, Antoine, Dhillon, Ripple, Devouassoux, Gilles, FitzGerald, J. Mark, Egron, Carole, Kanawaty, David, Falchero, Lionel, Kelly, Allan, Goupil, François, Killorn, William, Kessler, Romain, Landry, Daniel, Le Roux, Pascal, Luton, Robert, Mabire, Pascal, Mahay, Guillaume, Ide, Yumiko, Martinez, Stéphanie, Inomata, Minehiko, Melloni, Boris, Inoue, Hiromasa, Moreau, Laurent, Inoue, Koji, Raherison, Chantal, Inoue, Sumito, Riviere, Emilie, Kato, Motokazu, Roux-Claudé, Pauline, Kawasaki, Masayuki, Soulier, Michel, Kawayama, Tomotaka, Vignal, Guillaume, Kita, Toshiyuki, Yaici, Azzedine, Kobayashi, Kanako, Aries, Sven Philip, Koto, Hiroshi, Bals, Robert, Nishi, Koichi, Beck, Ekkehard, Saito, Junpei, Deimling, Andreas, Shimizu, Yasuo, Feimer, Jan, Shirai, Toshihiro, Grimm-Sachs, Vera, Sugihara, Naruhiko, Groth, Gesine, Takahashi, Ken-ichi, Herth, Felix, Tashimo, Hiroyuki, Hoheisel, Gerhard, Tomii, Keisuke, Kanniess, Frank, Yamada, Takashi, Lienert, Thomas, Yanai, Masaru, Mronga, Silke, Javier, Ruth Cerino, Reinhardt, Jörg, Domínguez Peregrina, Alfredo, Schlenska, Christian, Corzo, Marco Fernández, Stolpe, Christoph, Montano Gonzalez, Efraín, Teber, Ishak, Ramírez-Venegas, Alejandra, Timmermann, Hartmut, Rendon, Adrian, Ulrich, Thomas, Boersma, Willem, Velling, Peter, Djamin, R.S., Wehgartner-Winkler, Sabina, Eijsvogel, Michiel, Welling, Juergen, Franssen, Frits, Winkelmann, Ernst-Joachim, Goosens, Martijn, Barbetta, Carlo, Graat-Verboom, Lidwien, Braido, Fulvio, Veen, Johannes in 't, Cardaci, Vittorio, Janssen, Rob, Clini, Enrico Maria, Kuppens, Kim, Costantino, Maria Teresa, van den Berge, Maarten, Cuttitta, Giuseppina, van de Ven, Mario, di Gioacchino, Mario, Brunstad, Ole Petter, Fois, Alessandro, Einvik, Gunnar, Foschino-Barbaro, Maria Pia, Høines, Kristian Jong, Gammeri, Enrico, Khusrawi, Alamdar, Inchingolo, Riccardo, Oien, Torbjorn, Lavorini, Federico, Chang, Yoon-Seok, Molino, Antonio, Cho, Young Joo, Nucera, Eleonora, Hwang, Yong Il, Papi, Alberto, Kim, Woo Jin, Patella, Vincenzo, Koh, Young-Il, Pesci, Alberto, Lee, Byung-Jae, Ricciardolo, Fabio, Lee, Kwan-Ho, Rogliani, Paola, Lee, Sang-Pyo, Sarzani, Riccardo, Lee, Yong Chul, Vancheri, Carlo, Lim, Seong Yong, Vincenti, Rigoletta, Min, Kyung Hun, Endo, Takeo, Oh, Yeon-Mok, Fujita, Masaki, Park, Choon-Sik, Hara, Yu, Park, Hae-Sim, Horiguchi, Takahiko, Park, Heung-Woo, Hosoi, Keita, Rhee, Chin Kook, Yoon, Ho Joo, Morice, Alyn, Yoon, Hyoung-Kyu, Pandya, Preeti, García-Navarro, Alvar Agusti, Patel, Manish, Andújar, Rubén, Roy, Kay, Anoro, Laura, Sathyamurthy, Ramamurthy, García, María Buendía, Thiagarajan, Swaminathan, Mozo, Paloma Campo, Turner, Alice, Campos, Sergio, Vestbo, Jorgen, Maldonado, Francisco Casas, Wedzicha, Wisia, Castilla Martínez, Manuel, Wilkinson, Tom, Serrano, Carolina Cisneros, Wilson, Pete, Comeche Casanova, Lorena, Al-Asadi, Lo’Ay, Corbacho, Dolores, Anholm, James, Campo Matías, Felix Del, Averill, Frank, Echave-Sustaeta, Jose, Bansal, Sandeep, Corral, Gloria Francisco, Baptist, Alan, Gamboa Setién, Pedro, Campbell, Colin, García Clemente, Marta, Campos, Michael A., Núñez, Ignacio García, Chipps, Bradley, Robaina, Jose García, Crook, Gretchen, García Salmones, Mercedes, DeLeon, Samuel, Marín Trigo, Jose Maria, Eid, Alain, Fernandez, Marta Nuñez, Epstein, Ellen, Palomo, Sara Nuñez, Fritz, Stephen, Olaguibel Rivera, José, Harris, Hoadley, de Llano, Luis Pérez, Hewitt, Mitzie, Pueyo Bastida, Ana, Holguin, Fernando, Rañó, Ana, Hudes, Golda, Rodríguez González-Moro, José, Jackson, Richard, Reig, Albert Roger, Kaufman, Alan, Velasco Garrido, José, Kaufman, David, Curiac, Dan, Klapholz, Ari, Janson, Christer, Krishna, Harshavardhan, Lif-Tiberg, Cornelia, Lee, Daria, Luts, Anders, Lin, Robert, Råhlen, Lennart, Maselli-Caceres, Diego, Rustscheff, Stefan, Mehta, Vinay, Adams, Frances, Moy, James N., Bradman, Drew, Nwokoro, Ugo, Broughton, Emma, Parikh, Purvi, Cosgrove, John, Parikh, Sudhir, Flood-Page, Patrick, Perrino, Frank, Fuller, Elizabeth, Ruhlmann, James, Harrison, Timothy, Sassoon, Catherine, Hartley, David, Settipane, Russell A., Hattotuwa, Keith, Sousa, Daniel, Jones, Gareth, Sriram, Peruvemba, Lewis, Keir, Wachs, Richard, McGarvey, Lorcan, Golam, Sarowar Muhammad, Beasley, Richard, FitzGerald, J Mark, Harrison, Tim, Hughes, Rod, Müllerová, Hana, Olaguibel, José María, Rapsomaniki, Eleni, Reddel, Helen K., and Sadatsafavi, Mohsen
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- 2022
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28. Frequent productive cough: Symptom burden and future exacerbation risk among patients with asthma and/or COPD in the NOVELTY study
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Benhabib, Gabriel, Ruiz, Xavier Bocca, Olmo, Ricardo del, Lisanti, Raul Eduardo, Marino, Gustavo, Mattarucco, Walter, Nogueira, Juan, Parody, Maria, Pascale, Pablo, Rodriguez, Pablo, Silva, Damian, Svetliza, Graciela, Victorio, Carlos F., Rolon, Roxana Willigs, Yañez, Anahi, Baines, Stuart, Bowler, Simon, Bremner, Peter, Bull, Sheetal, Carroll, Patrick, Chaalan, Mariam, Farah, Claude, Hammerschlag, Gary, Hancock, Kerry, Harrington, Zinta, Katsoulotos, Gregory, Kim, Joshua, Langton, David, Lee, Donald, Peters, Matthew, Prassad, Lakshman, Reddel, Helen, Sajkov, Dimitar, Santiago, Francis, Simpson, Frederick Graham, Tai, Sze, Thomas, Paul, Wark, Peter, Delfini Cançado, José Eduardo, Cunha, Thúlio, Lima, Marina, Cardoso, Alexandre Pinto, Rabahi, Marcelo, Anees, Syed, Bertley, John, Bell, Alan, Cheema, Amarjit, Chouinard, Guy, Csanadi, Michael, Dhar, Anil, Dhillon, Ripple, FitzGerald, J. Mark, Kanawaty, David, Kelly, Allan, Killorn, William, Landry, Daniel, Luton, Robert, Mandhane, Piushkumar, McIvor, Andrew, Pek, Bonavuth, Petrella, Robert, Stollery, Daniel, Chen, Meihua, Chen, Yan, Gu, Wei, Christopher Hui, Kim Ming, Li, Manxiang, Li, Shiyue, Lijun, Ma, Qin, Guangyue, Song, Weidong, Tan, Wei, Tang, Yijun, Wang, Chen, Wang, Tan, Wen, Fuqiang, Wu, Feng, Xiang, PingChao, Xiao, Zuke, Xiong, Shengdao, Yang, Jinghua, Yang, Jingping, Zhang, Caiqing, Zhang, Min, Zhang, Ping, Zhang, Wei, Zheng, Xiaohe, Zhu, Dan, Grimaldos, Fabio Bolivar, Arboleda, Alejandra Cañas, Bueno, Carlos Matiz, Molina de Salazar, Dora, Bendstrup, Elisabeth, Hilberg, Ole, Kjellerup, Carsten, Weinreich, Ulla, Bonniaud, Philippe, Brun, Olivier, Burgel, Pierre-Régis, Chouaid, Christos, Couturaud, Francis, de Blic, Jacques, Debieuvre, Didier, Delsart, Dominique, Demaegdt, Axelle, Demoly, Pascal, Deschildre, Antoine, Devouassoux, Gilles, Egron, Carole, Falchero, Lionel, Goupil, François, Kessler, Romain, Le Roux, Pascal, Mabire, Pascal, Mahay, Guillaume, Martinez, Stéphanie, Melloni, Boris, Moreau, Laurent, Raherison, Chantal, Riviere, Emilie, Roux-Claudé, Pauline, Soulier, Michel, Vignal, Guillaume, Yaici, Azzedine, Aries, Sven Philip, Bals, Robert, Beck, Ekkehard, Deimling, Andreas, Feimer, Jan, Grimm-Sachs, Vera, Groth, Gesine, Herth, Felix, Hoheisel, Gerhard, Kanniess, Frank, Lienert, Thomas, Mronga, Silke, Reinhardt, Jörg, Schlenska, Christian, Stolpe, Christoph, Teber, Ishak, Timmermann, Hartmut, Ulrich, Thomas, Velling, Peter, Wehgartner-Winkler, Sabina, Welling, Juergen, Winkelmann, Ernst-Joachim, Barbetta, Carlo, Braido, Fulvio, Cardaci, Vittorio, Clini, Enrico Maria, Costantino, Maria Teresa, Cuttitta, Giuseppina, di Gioacchino, Mario, Fois, Alessandro, Foschino-Barbaro, Maria Pia, Gammeri, Enrico, Inchingolo, Riccardo, Lavorini, Federico, Molino, Antonio, Nucera, Eleonora, Papi, Alberto, Patella, Vincenzo, Pesci, Alberto, Ricciardolo, Fabio, Rogliani, Paola, Sarzani, Riccardo, Vancheri, Carlo, Vincenti, Rigoletta, Endo, Takeo, Fujita, Masaki, Hara, Yu, Horiguchi, Takahiko, Hosoi, Keita, Ide, Yumiko, Inomata, Minehiko, Inoue, Hiromasa, Inoue, Koji, Inoue, Sumito, Kato, Motokazu, Kawasaki, Masayuki, Kawayama, Tomotaka, Kita, Toshiyuki, Kobayashi, Kanako, Koto, Hiroshi, Nishi, Koichi, Saito, Junpei, Shimizu, Yasuo, Shirai, Toshihiro, Sugihara, Naruhiko, Takahashi, Ken-ichi, Tashimo, Hiroyuki, Tomii, Keisuke, Yamada, Takashi, Yanai, Masaru, Javier, Ruth Cerino, Peregrina, Alfredo Domínguez, Corzo, Marco Fernández, Gonzalez, Efraín Montano, Ramírez-Venegas, Alejandra, Rendon, Adrian, Boersma, Willem, Djamin, R.S., Eijsvogel, Michiel, Franssen, Frits, Goosens, Martijn, Graat-Verboom, Lidwien, Veen, Johannes in 't, Janssen, Rob, Kuppens, Kim, van den Berge, Maarten, van de Ven, Mario, Brunstad, Ole Petter, Einvik, Gunnar, Høines, Kristian Jong, Khusrawi, Alamdar, Oien, Torbjorn, Chang, Yoon-Seok, Cho, Young Joo, Hwang, Yong Il, Kim, Woo Jin, Koh, Young-Il, Lee, Byung-Jae, Lee, Kwan-Ho, Lee, Sang-Pyo, Lee, Yong Chul, Lim, Seong Yong, Min, Kyung Hun, Oh, Yeon-Mok, Park, Choon-Sik, Park, Hae-Sim, Park, Heung-Woo, Rhee, Chin Kook, Yoon, Ho Joo, Yoon, Hyoung-Kyu, García-Navarro, Alvar Agusti, Andújar, Rubén, Anoro, Laura, García, María Buendía, Mozo, Paloma Campo, Campos, Sergio, Maldonado, Francisco Casas, Martínez, Manuel Castilla, Serrano, Carolina Cisneros, Casanova, Lorena Comeche, Corbacho, Dolores, Del Campo Matías, Felix, Echave-Sustaeta, Jose, Corral, Gloria Francisco, Setién, Pedro Gamboa, Clemente, Marta García, Núñez, Ignacio García, Robaina, Jose García, Salmones, Mercedes García, Marín Trigo, Jose Maria, Fernandez, Marta Nuñez, Palomo, Sara Nuñez, Rivera, José Olaguibel, Pérez de Llano, Luis, Bastida, Ana Pueyo, Rañó, Ana, González-Moro, José Rodríguez, Reig, Albert Roger, Garrido, José Velasco, Curiac, Dan, Janson, Christer, Lif-Tiberg, Cornelia, Luts, Anders, Råhlen, Lennart, Rustscheff, Stefan, Adams, Frances, Bradman, Drew, Broughton, Emma, Cosgrove, John, Flood-Page, Patrick, Fuller, Elizabeth, Harrison, Timothy, Hartley, David, Hattotuwa, Keith, Jones, Gareth, Lewis, Keir, McGarvey, Lorcan, Morice, Alyn, Pandya, Preeti, Patel, Manish, Roy, Kay, Sathyamurthy, Ramamurthy, Thiagarajan, Swaminathan, Turner, Alice, Vestbo, Jorgen, Wedzicha, Wisia, Wilkinson, Tom, Wilson, Pete, Al-Asadi, Lo’Ay, Anholm, James, Averill, Frank, Bansal, Sandeep, Baptist, Alan, Campbell, Colin, Campos, Michael A., Chipps, Bradley, Crook, Gretchen, DeLeon, Samuel, Eid, Alain, Epstein, Ellen, Fritz, Stephen, Harris, Hoadley, Hewitt, Mitzie, Holguin, Fernando, Hudes, Golda, Jackson, Richard, Kaufman, Alan, Kaufman, David, Klapholz, Ari, Krishna, Harshavardhan, Lee, Daria, Lin, Robert, Maselli-Caceres, Diego, Mehta, Vinay, Moy, James N., Nwokoro, Ugo, Parikh, Purvi, Parikh, Sudhir, Perrino, Frank, Ruhlmann, James, Sassoon, Catherine, Settipane, Russell A., Sousa, Daniel, Sriram, Peruvemba, Wachs, Richard, Hughes, Rod, Rapsomaniki, Eleni, Keen, Christina, Make, Barry J., Tomaszewski, Erin L., Müllerová, Hana, and Reddel, Helen K.
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- 2022
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29. A systematic review of blood eosinophils and continued treatment with inhaled corticosteroids in patients with COPD
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Dalin, Dagmar Abelone, Løkke, Anders, Kristiansen, Pernille, Jensen, Charlotte, Birkefoss, Kirsten, Christensen, Hanne Rolighed, Godtfredsen, Nina Skavlan, Hilberg, Ole, Rohde, Jeanett Friis, Ussing, Anja, Vermehren, Charlotte, and Händel, Mina Nicole
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- 2022
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30. Impaired phosphate transport in SLC34A2 variants in patients with pulmonary alveolar microlithiasis
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Jönsson, Åsa Lina M., Hernando, Nati, Knöpfel, Thomas, Mogensen, Susie, Bendstrup, Elisabeth, Hilberg, Ole, Christensen, Jane Hvarregaard, Simonsen, Ulf, and Wagner, Carsten A.
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- 2022
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31. Pharmacological smoking cessation of adults aged 30–50 years with COPD
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Andelius, Dea Kejlberg, Hilberg, Ole, Ibsen, Rikke, and Løkke, Anders
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- 2022
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32. Experiences of receiving a medical consultation – an interview study among hospitalized psychiatric patients.
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Wolsing, Sofie Krogh, Hjorth, Peter, Løkke, Anders, Hilberg, Ole, and Frølund, Jannie Christina
- Subjects
PEOPLE with mental illness ,MEDICAL consultation ,PATIENT experience ,PHYSICIANS ,PATIENTS' attitudes - Abstract
Purpose: People with mental illness often experience more physical health problems, compared to the general population. Therefore, we conducted medical consultations to hospitalized psychiatric patients. The purpose of our study was to investigate experiences of medical consultations from a patient perspective. Materials and methods: We conducted 17 qualitative, semi-structured interviews with hospitalized psychiatric patients who received a medical consultation in the period of February to May 2023. The interviews were analyzed using Braun and Clarke's thematic analysis. Results: Patients perceived the medical consultation as important in bridging the gap between psychiatric and somatic treatment. The consultation created a sense of security, with patients emphasizing the importance of acknowledgment by the medical doctor. However, some patients were affected by their state of mind and their psychiatric treatment, resulting in memory impairment, which prevented fully utilization of the medical consultation. The support from psychiatric staff proved crucial for patients in initiating somatic interventions. The results are presented in the two overarching themes: (1) Experiences of a medical consultation in a psychiatric setting and (2) communication and support as influential factors for benefits of the medical consultation. Conclusion: Our interview study reveals that hospitalized psychiatric patients experience a medical consultation as an important initiative. The relationship between the patient and the medical doctor, the patient's state of mind, and the support of the psychiatric staff play significant roles. Incorporating these factors in the medical consultation enables a beneficial outcome that can improve the health of people with mental illness. [ABSTRACT FROM AUTHOR]
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- 2024
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33. Inhaled corticosteroid treatment and pneumonia in patients with chronic obstructive pulmonary disease – nationwide development from 1998 to 2018
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Klitgaard, Allan, primary, Ibsen, Rikke, additional, Lykkegaard, Jesper, additional, Hilberg, Ole, additional, and Løkke, Anders, additional
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- 2024
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34. Lung Cancer among outpatients with Chronic Obstructive Pulmonary Disease - A seven-year cohort Study
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Bang Henriksen, Margrethe, primary, Hansen, Torben Frøstrup, additional, Jensen, Lars Henrik, additional, Brasen, Claus Lohman, additional, Borg, Morten, additional, Hilberg, Ole, additional, and Løkke, Anders, additional
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- 2024
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35. Sarcoidosis: A nationwide registry-based study of incidence, prevalence and diagnostic work-up
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Sikjær, Melina Gade, Hilberg, Ole, Ibsen, Rikke, and Løkke, Anders
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- 2021
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36. Clusters of comorbidities in idiopathic pulmonary fibrosis
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Prior, Thomas Skovhus, Hoyer, Nils, Hilberg, Ole, Shaker, Saher Burhan, Davidsen, Jesper Rømhild, Rasmussen, Finn, and Bendstrup, Elisabeth
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- 2021
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37. Performance of the EarlyCDT® Lung test in detection of lung cancer and pulmonary metastases in a high-risk cohort
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Borg, Morten, Wen, Sara W.C., Nederby, Line, Hansen, Torben Frøstrup, Jakobsen, Anders, Andersen, Rikke Fredslund, Weinreich, Ulla Møller, and Hilberg, Ole
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- 2021
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38. The impact of shared decision making on time consumption and clinical decisions. A prospective cohort study
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Søndergaard, Stine R., Madsen, Poul H., Hilberg, Ole, Bechmann, Troels, Jakobsen, Erik, Jensen, Karina M., Olling, Karina, and Steffensen, Karina D.
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- 2021
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39. Geographical and socioeconomic differences in compliance with and access to allergen immunotherapy in Denmark: A nationwide registry-based study – 1998-2016
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Borg, Morten, Løkke, Anders, and Hilberg, Ole
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- 2021
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40. Onset of effect and impact on health-related quality of life, exacerbation rate, lung function, and nasal polyposis symptoms for patients with severe eosinophilic asthma treated with benralizumab (ANDHI): a randomised, controlled, phase 3b trial
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Pohl, Wolfgang, Voves, Robert, Deschampheleire, Maud, Louis, Renaud, Martinot, Jean-Benoit, Peché, Rudi, Chapman, Kenneth, Cheema, Amarjit, Dorscheid, Delbert, FitzGerald, J. Mark, Gagnon, Remi, Killorn, William Patrick, Olivenstein, Ronald, Philteos, George, Ramsey, Clare, Rolf, J. Douglass, Walker, Brandie, Hilberg, Ole, Skjold, Tina, Titlestad, Ingrid, Hakulinen, Auli, Kilpeläinen, Maritta, Ben Hayoun, Michèle, Bonniaud, Philippe, Bourdin, Arnaud, Chanez, Pascal, De Blay, Frédéric, Deslee, Gaëtan, Devouassoux, Gilles, Didier, Alain, Douadi, Youcef, Fry, Stéphanie, Garcia, Gilles, Girodet, Pierre-Olivier, Leroyer, Christophe, Magnan, Antoine, Mahay, Guillaume, Nocent, Cécilia, Pison, Christophe, Roux, Pauline-Marie, Taillé, Camille, Tiotiu, Juliana-Angelica, Beck, Ekkehard, Jandl, Margret, Kaehler, Christian, Kässner, Frank, Koesters, Frank, Kronsbein, Juliane, Schaum, Thomas, Schulz, Christian, Skowasch, Dirk, Taube, Christian, Welte, Tobias, de Roux, Andrés, Beghé, Bianca, Blasi, Francesco, Canonica, Giorgio Walter, Carpagnano, Giovanna, Caruso, Cristiano, Corsico, Angelo Guido, Constantino, Elio, Crimi, Nunzio, Maestrelli, Piero, Menzella, Francesco, Milanese, Manlio, Papi, Alberto, Pelaia, Girolamo, Pini, Laura, Santus, Pierachille, Savi, Eleonora, Scichilone, Nicola, Senna, Gianenrico, Spadaro, Giuseppe, Vaghi, Adriano, Gans, Steven, Hölters, Jurgen, Langeveld, B., Pieters, Willem, Staaks, G.H.A., van Veen, Ilonka, van den Berg, J.W.K., Einvik, Gunnar, Lehmann, Sverre, Ali García, Ismael, Almonacid, Carlos, Bobolea, Irina, Campo Mozo, Paloma, de Luiz, Gustavo, Domingo Ribas, Christian, Echave-Sustaeta María-Tomé, José María, García Rivero, Juan Luis, García-Cosío Piqueras, Borja, Gómez-Bastero Fernández, Ana, González Pérez, Ruperto, Henríquez Santa, Aythamy, Martínez Rivera, Carlos, Muñoz Gall, Xavier, Ramos, Jacinto, Gregorio Soto Campos, Jose, Vidal Pan, Carmen, Stenfors, Nikolai, Tunsäter, Alf, Vinge, Ines, Chaudhuri, Rekha, Harrison, Timothy, Mansur, Adel, Nasser, Shuaib, Nordstrom, Monica, Pfeffer, Paul, Saralaya, Dinesh, Short, Philip, Adlakha, Arun, Alpan, Oral, Averill, Francis, Badhwar, Anil, Bardelas, Jose, Baxter, Barbara, Bensch, George, Berger, William, Bernstein, Jonathan, Bridges, Tracy, Brimeyer, Ryan, Calhoun, William, Campbell, Edward, Cherry, William Brett, Chupp, Geoffrey, Clore, Lee, Cohn, John, Cole, Jeremy, Condemi, John, Cury, James, Davis, Benjamin, DeLeon, Samuel, Delacruz, Luis, Diaz, Joseph, Erb, David, Eziri, Emeka, Fakih, Faisal, Fiedler, Douglas, Fost, David, Fritz, Stephen, Gonzalez, Erika, Goodman, Brad, Gottlieb, Peter, Gottschlich, Gregory, Gower, Richard, Hajal, Rizan, Harris, James, Heidarian-Raissy, Hengameh, Heyder, Albrecht, Hill, David, Holguin, Fernando, Hussain, Iftikhar, Illowite, Jonathan, Jacobs, Joshua, Jarratt, Mikell, Kaiser, Harold, Kao, Neil, Kashyap, Ravindra, Kaufman, David, Kent, Edward, Kim, Kenneth, Klein, Ryan, Kraft, Monica, Kono, Ritsu, Kureishy, Shahrukh, Leflein, Jeffrey, Leong, Mila, Li, Huamin, Lin, Robert, Lugogo, Njira, Marcus, Michael, Maselli Caceres, Diego Jose, Mehta, Vinay, Mello, Curtis, Millard, Mark, Milstone, Aaron, Mohan, Arjun, Moore, Wendy, Moss, Mark, Mumneh, Nayla, O'Brien, Thomas, Ostransky, David, Palumbo, Michael, Parikh, Purvi, Parikh, Sudhir, Patel, Amit, Perez, Guido, Pleskow, Warren, Prenner, Bruce, Puppala, Dileep, Ramey, John, Reibman, Joan, Reyes, Ramon, Robinette, Emory, Rodicio, Ileana, Ryan, Stephen, Sekhsaria, Sudhir, Sigal, Barry, Sikand, Vinay, Soong, Weily, Spangenthal, Selwyn, St. John, Roy, Steven, Gary, Subramaniam, Vijay, Sumino, Kaharu, Sztejman, Eric, Tan, Ricardo A., Tanus, Tonny, Thompson, Charles, Thornblade, Carl, Villareal, Manuel, Wenzel, Sally, Zafra, Heidi, Ziedalski, Tomasz, Harrison, Tim W, Cosio, Borja G, Lugogo, Njira L, Burden, Annie, McDermott, Lawrence, Garcia Gil, Esther, and Zangrilli, James G
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- 2021
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41. DUPILUMAB SAFETY AND EFFICACY IN A REAL-WORLD CLINICAL SETTING: THE RAPID ASTHMA REGISTRY
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PETERS, ANJU T, HILBERG, OLE, LUGOGO, NJIRA L, RAMSEY, ALLISON C, SHAO, LIYANG, DE PRADO GOMEZ, LUCIA, JACOB-NARA, JUBY A, SACKS, HARRY, ROWE, PAUL J, DENIZ, YAMO, and GALL, REBECCA
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- 2024
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42. BASELINE CHARACTERISTICS AND COEXISTING TYPE 2 INFLAMMATORY DISEASES OF PATIENTS WITH ASTHMA INITIATING DUPILUMAB IN A REAL-WORLD SETTING: THE RAPID REGISTRY
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LUGOGO, NJIRA L, PETERS, ANJU T, CÔTÉ, ANDRÉANNE, HILBERG, OLE, HEFFLER, ENRICO, MUNOZ, XAVIER, VINGE, INES, MANSUR, ADEL, NAGASE, HIROYUKI, SHAO, LIYANG, GALL, REBECCA, DE PRADO GOMEZ, LUCIA, JACOB-NARA, JUBY A, SACKS, HARRY, ROWE, PAUL J, DENIZ, YAMO, and BOURDIN, ARNAUD
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- 2024
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43. High yield from repeated testing for tuberculosis among high-risk citizens in Denmark
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Staerke, Nina Breinholt, Smidt-Hansen, Torben, Oldenborg, Leni, Jensen, Torben Tranborg, Weinreich, Ulla Møller, Shakar, Shakil, Wejse, Christian, Hilberg, Ole, and Fløe, Andreas
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- 2021
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44. Baseline Systemic Oral Corticosteroid Use in Patients with Asthma Initiating Dupilumab Treatment in the Real World: From the RAPID Global Registry
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Lugogo,Nijra, Heffler,Enrico, Plaza,Vicente, Hilberg,Ole, Xia,Changming, Nash,Scott, Pandit,Nami, Jacob-Nara,Juby, Sacks,Harry, Rowe,Paul, Deniz,Yamo, Hardin,Megan, Soler,Xavier, Lugogo,Nijra, Heffler,Enrico, Plaza,Vicente, Hilberg,Ole, Xia,Changming, Nash,Scott, Pandit,Nami, Jacob-Nara,Juby, Sacks,Harry, Rowe,Paul, Deniz,Yamo, Hardin,Megan, and Soler,Xavier
- Abstract
Nijra L Lugogo,1 Enrico Heffler,2,3 Vicente Plaza,4 Ole Hilberg,5 Changming Xia,6 Scott Nash,6 Nami Pandit,7 Juby A Jacob-Nara,7 Harry J Sacks,6 Paul J Rowe,7 Yamo Deniz,6 Megan Hardin,8 Xavier Soler6 1University of Michigan Medical School, Ann Arbor, MI, USA; 2IRCCS Humanitas Research Hospital, Rozzano, Milan, Italy; 3Humanitas University, Pieve Emanuele, Milan, Italy; 4Hospital de la Santa Creu i Sant Pau, Barcelona, Spain; 5Lillebaelt Hospital, Vejle, Denmark; 6Regeneron Pharmaceuticals Inc., Tarrytown, NY, USA; 7Sanofi, Bridgewater, NJ, USA; 8Sanofi, Cambridge, MA, USACorrespondence: Nijra L Lugogo, University of Michigan Medical School, 300 North Ingalls St, Suite 2C40, Ann Arbor, MI, 48109, USA, Email nlugogo@med.umich.edu
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- 2024
45. Prevalence estimates of tuberculosis infection in adults in Denmark:a retrospective nationwide register-based cross-sectional study, 2010 to 2018
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Østergaard, Anne Ahrens, Lillebaek, Troels, Petersen, Inge, Fløe, Andreas, Worren Bøkan, Eliza H., Hilberg, Ole, Holden, Inge K., Larsen, Lone, Colic, Ada, Wejse, Christian, Ravn, Pernille, Nørgård, Bente Mertz, Bjerrum, Stephanie, Johansen, Isik Somuncu, Østergaard, Anne Ahrens, Lillebaek, Troels, Petersen, Inge, Fløe, Andreas, Worren Bøkan, Eliza H., Hilberg, Ole, Holden, Inge K., Larsen, Lone, Colic, Ada, Wejse, Christian, Ravn, Pernille, Nørgård, Bente Mertz, Bjerrum, Stephanie, and Johansen, Isik Somuncu
- Abstract
What did you want to address in this study and why? We wanted to estimate the prevalence of tuberculosis infection in people aged between 15 and 64 years in Denmark. Tuberculosis infection refers to infection with Mycobacterium tuberculosis without disease. Tuberculosis is a disease that can be eliminated and the World Health Organization aims to achieve this by 2035. To accomplish this goal, it is necessary to identify and treat people with tuberculosis infection, since they represent a potential reservoir of tuberculosis. What have we learnt from this study? The prevalence of tuberculosis infection in adolescents and adults Denmark is 3.2%, corresponding to ca 200,000 people infected with the tuberculosis bacterium. This suggests a reservoir of 10,000 to 20,000 potential tuberculosis cases in the future. The prevalence of tuberculosis infection increases with age and the incidence rate in the country of birth. What are the implications of your findings for public health? Systematic screening for tuberculosis infection and preventive treatment should be implemented for people with immunosuppression or from countries with a tuberculosis incidence rate greater than 10 per 100,000 population., Background: Tuberculosis (TB) elimination requires identifying and treating persons with TB infection (TBI). Aim: We estimate the prevalence of positive interferon gamma release assay (IGRA) tests (including TB) and TBI (excluding TB) in Denmark based on TBI screening data from patients with inflammatory bowel disease (IBD) or inflammatory rheumatic disease (IRD). Methods: Using nationwide Danish registries, we included all patients with IBD or IRD with an IGRA test performed between 2010 and 2018. We estimated the prevalence of TBI and positive IGRA with 95% confidence intervals (CI) in adolescents and adults aged 15–64 years after sample weighting adjusting for distortions in the sample from the background population of Denmark for sex, age group and TB incidence rates (IR) in country of birth. Results: In 13,574 patients with IBD or IRD, 12,892 IGRA tests (95.0%) were negative, 461 (3.4%) were positive and 221 (1.6%) were indeterminate, resulting in a weighted TBI prevalence of 3.2% (95% CI: 2.9–3.5) and weighted positive IGRA prevalence of 3.8% (95% CI: 3.5–4.2) among adults aged 15–64 years in the background population of Denmark. Unweighted TBI prevalence increased with age and birthplace in countries with a TB IR higher than 10/100,000 population. Conclusion: Estimated TBI prevalence is low in Denmark. We estimate that 200,000 persons have TBI and thus are at risk of developing TB. Screening for TBI and preventive treatment, especially in persons born in high TB incidence countries or immunosuppressed, are crucial to reduce the risk of and eliminate TB.
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- 2024
46. Consequences of Losing Incidental Pulmonary Nodules to Follow-Up:Unmonitored Nodules Progressing to Stage IV Lung Cancer
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Borg, Morten, Kristensen, Katrine, Alstrup, Gitte, Mamaeva, Tatiana, Arshad, Arman, Laursen, Christian B., Hilberg, Ole, Bodtger, Uffe, Andersen, Michael Brun, Rasmussen, Torben Riis, Borg, Morten, Kristensen, Katrine, Alstrup, Gitte, Mamaeva, Tatiana, Arshad, Arman, Laursen, Christian B., Hilberg, Ole, Bodtger, Uffe, Andersen, Michael Brun, and Rasmussen, Torben Riis
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Introduction: Lung cancer is the leading cause of cancer-related death globally. Incidental pulmonary nodules represent a golden opportunity for early diagnosis, which is critical for improving survival rates. This study explores the impact of missed pulmonary nodules on the progression of lung cancer. Methods: A total of 4,066 stage IV lung cancer cases from 2019 to 2021 in Danish hospitals were investigated to determine whether a chest computed tomography (CT) had been performed within 2 years before diagnosis. CT reports and images were reviewed to identify nodules that had been missed by radiologists or were not appropriately monitored, despite being mentioned by the radiologist, and to assess whether these nodules had progressed to stage IV lung cancer. Results: Among stage IV lung cancer patients, 13.6% had undergone a chest CT scan before their diagnosis; of these, 44.4% had nodules mentioned. Radiologists missed a nodule in 7.6% of cases. In total, 45.3% of nodules were not appropriately monitored. An estimated 2.5% of stage IV cases could have been detected earlier with proper surveillance. Conclusion: This study underlines the significance of monitoring pulmonary nodules and proposes strategies for enhancing detection and surveillance. These strategies include centralized monitoring and the implementation of automated registries to prevent gaps in follow-up., Introduction: Lung cancer is the leading cause of cancer-related death globally. Incidental pulmonary nodules represent a golden opportunity for early diagnosis, which is critical for improving survival rates. This study explores the impact of missed pulmonary nodules on the progression of lung cancer. Methods: A total of 4,066 stage IV lung cancer cases from 2019 to 2021 in Danish hospitals were investigated to determine whether a chest computed tomography (CT) had been performed within 2 years before diagnosis. CT reports and images were reviewed to identify nodules that had been missed by radiologists or were not appropriately monitored, despite being mentioned by the radiologist, and to assess whether these nodules had progressed to stage IV lung cancer. Results: Among stage IV lung cancer patients, 13.6% had undergone a chest CT scan before their diagnosis; of these, 44.4% had nodules mentioned. Radiologists missed a nodule in 7.6% of cases. In total, 45.3% of nodules were not appropriately monitored. An estimated 2.5% of stage IV cases could have been detected earlier with proper surveillance. Conclusion: This study underlines the significance of monitoring pulmonary nodules and proposes strategies for enhancing detection and surveillance. These strategies include centralized monitoring and the implementation of automated registries to prevent gaps in follow-up.
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- 2024
47. Lung cancer among outpatients with COPD: a 7-year cohort study.
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Henriksen, Margrethe Bang, Hansen, Torben Frøstrup, Jensen, Lars Henrik, Brasen, Claus Lohman, Borg, Morten, Hilberg, Ole, and Løkke, Anders
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- 2024
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48. Baseline Systemic Oral Corticosteroid Use in Patients with Asthma Initiating Dupilumab Treatment in the Real World: From the RAPID Global Registry.
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Lugogo, Nijra L, Heffler, Enrico, Plaza, Vicente, Hilberg, Ole, Xia, Changming, Nash, Scott, Pandit, Nami, Jacob-Nara, Juby A, Sacks, Harry J, Rowe, Paul J, Deniz, Yamo, Hardin, Megan, and Soler, Xavier
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FORCED expiratory volume ,ASTHMATICS ,EXPIRATORY flow ,EMPLOYEE ownership ,ADRENERGIC beta agonists - Abstract
This article discusses the baseline characteristics of patients with asthma who are initiating treatment with the medication dupilumab in a real-world setting. The study is part of the Registry of Asthma Patients Initiating DUPIXENT (RAPID), which aims to collect information on the use and effectiveness of dupilumab for asthma in a clinical setting. The analysis found that 25% of the patients had used oral corticosteroids (OCS) in the three months prior to enrollment or were currently using them. Patients with and without a history of OCS use had similarly impaired lung function, indicating a high treatment need. The findings suggest that many patients in the real-world asthma population require additional therapy to reduce OCS use. [Extracted from the article]
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- 2024
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49. Compliance in subcutaneous and sublingual allergen immunotherapy: A nationwide study
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Borg, Morten, Løkke, Anders, and Hilberg, Ole
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- 2020
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50. Will the new treatment recommendations for asthma increase adverse events?
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Dalin, Dagmar A., Koch, Nicoline E., and Hilberg, Ole
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- 2022
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