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31 results on '"Hicks, Lauren"'

7. Abstract 6072: Chromosomal aneuploidy, whole-genome doubling and mutational signatures in NCI PDMR models

Author

Chen, Li, primary, Das, Biswajit, additional, Chang, Ting-Chia, additional, Evrard, Yvonne A., additional, Karlovich, Chris A., additional, Chapman, Alyssa, additional, Fullmer, Brandie, additional, Hayes, Ashley, additional, Thornton, Ruth, additional, Nair, Nikitha, additional, Jiwani, Shahanawaz, additional, Dutko, Lindsay, additional, Benauer, Kelly, additional, Rivera, Gloryvee, additional, Camalier, Corinne, additional, Carter, John, additional, Borgel, Suzanne, additional, Miner, Tiffanie, additional, McGlynn, Chelsea, additional, Mills, Justine, additional, Uzelac, Shannon, additional, Shearer, Tia, additional, Hicks, Lauren, additional, Norris, Michelle, additional, Border, Carley, additional, Alcoser, Sergio, additional, Walsh, Thomas, additional, Mullendore, Michael, additional, Eugeni, Michelle, additional, Newton, Dianne, additional, Hollingshead, Melinda G., additional, Williams, P. Mickey, additional, and Doroshow, James H., additional

Published
2023
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8. Abstract 2050: Molecular subclassification of NCI PDMR breast cancer models using PAM50 gene expression signature

Author

Wu, Peter I., primary, Dutko, Lindsay, additional, Jiwani, Shahanawaz, additional, Chen, Li, additional, Das, Biswajit, additional, Chang, Ting-Chia, additional, Evrard, Yvonne A., additional, Karlovich, Chris A., additional, Chapman, Alyssa, additional, Fullmer, Brandie, additional, Hayes, Ashley, additional, Thornton, Ruth, additional, Nair, Nikitha, additional, Benauer, Kelly, additional, Rivera, Gloryvee, additional, Forbes, Thomas, additional, Carter, John, additional, Borgel, Suzanne, additional, Miner, Tiffanie, additional, McGlynn, Chelsea, additional, Mills, Justine, additional, Uzelac, Shannon, additional, Shearer, Tia, additional, Hicks, Lauren, additional, Norris, Michelle, additional, Border, Carley, additional, Alcoser, Sergio, additional, Walsh, Thomas, additional, Mullendore, Michael, additional, Eugeni, Michelle, additional, Newton, Dianne, additional, Hollingshead, Melinda G., additional, Williams, P. M., additional, and Doroshow, James H., additional

Published
2023
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10. OFCCP Proposes Two-Step Complaint Intake Process

Author

Hicks, Lauren B.

Subjects
United States. Office of Federal Contract Compliance Programs -- Powers and duties, Contractors -- Laws, regulations and rules, Public contracts -- Laws, regulations and rules -- Investigations, Company legal issue, Government regulation, Government contract, Business, international
Abstract

On January 18, 2023, the Office of Federal Contract Compliance Programs (OFCCP) published a notice proposing to modify its complaint process by adding a pre-complaint step whereby a complainant would [...]

Published
2023

12. Abstract 3120: Method development for generation of PDX models from rapid autopsy samples for the NCI patient-derived models repository

Author

Evrard, Yvonne A., primary, Eugeni, Michelle, additional, Ahalt-Gottholm, Michelle, additional, Bonomi, Carrie, additional, Borgel, Suzanne, additional, Caffrey, Thomas C., additional, Carter, John, additional, Chang, Ting-Chia, additional, Chen, Li, additional, Cooper, Kevin, additional, Das, Biswajit, additional, Delaney, Emily, additional, Dougherty, Kelly, additional, Duregon, Eleonora, additional, Ecker, Stephanie, additional, Geraghty, Joe, additional, Gibson, Marion, additional, Hicks, Lauren, additional, Hull, Jenna, additional, Veldt, Sharon Int, additional, Jiwani, Shahanawaz, additional, Karlovich, Chris A., additional, Loewenstein, Jade, additional, Mallow, Candace, additional, McGlynn, Chelsea, additional, Mills, Justine, additional, Miner, Tiffanie, additional, Schneider, Jowaly, additional, Shearer, Tia, additional, Styers, Savanna, additional, Uzelac, Shannon, additional, Grandgenett, Paul, additional, Hollingsworth, Michael, additional, Hooper, Jody E., additional, Williams, P. Mickey, additional, Hollingshead, Melinda, additional, and Doroshow, James H., additional

Published
2022
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20. 64Cu-SARTATE PET Imaging of Patients with Neuroendocrine Tumors Demonstrates High Tumor Uptake and Retention, Potentially Allowing Prospective Dosimetry for Peptide Receptor Radionuclide Therapy

Author

Hicks, Rodney J., primary, Jackson, Price, additional, Kong, Grace, additional, Ware, Robert E., additional, Hofman, Michael S., additional, Pattison, David A., additional, Akhurst, Timothy A., additional, Drummond, Elizabeth, additional, Roselt, Peter, additional, Callahan, Jason, additional, Price, Roger, additional, Jeffery, Charmaine M., additional, Hong, Emily, additional, Noonan, Wayne, additional, Herschtal, Alan, additional, Hicks, Lauren J., additional, Hedt, Amos, additional, Harris, Matthew, additional, Paterson, Brett M., additional, and Donnelly, Paul S., additional

Published
2018
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21. Through The Veil: OFCCP's Transparency Results In Even Minor Contractor Violations Being Published By The Agency

Author

Hicks , Lauren B.

Subjects
United States. Office of Federal Contract Compliance Programs -- Powers and duties, Government contractors -- Laws, regulations and rules, Conciliation (Civil procedure) -- Evaluation -- Laws, regulations and rules, Freedom of information, Regulatory compliance, Government regulation, Business, international, Freedom of Information Act
Abstract

Recently, the Office of Federal Contract Compliance Programs (OFCCP) began posting in its Freedom of Information Act (FOIA) Library links to conciliation agreements between the agency and federal contractors that [...]

Published
2019

22. Key Personnel Changes At OFCCP

Author

Hicks, Lauren B.

Subjects
Employment discrimination -- Laws, regulations and rules, Government regulation, Business, international
Abstract

With any change in presidential administration, it is typical to see turnover of the highest-ranking personnel in a federal agency. Those transitions appear to be occurring rapidly at the Office [...]

Published
2018

23. More Transparency At The OFCCP: New Protocol To Standardize Use Of Predetermination Notices

Author

Hicks, Lauren B.

Subjects
Employment discrimination -- Laws, regulations and rules -- Cases, Government contracts -- Cases, Business, international
Abstract

In a move toward greater transparency, the Office of Federal Contract Compliance Programs (OFCCP) recently issued Directive 2018-01 affecting the use of predetermination notices (PDNs) in discrimination cases. OFCCP uses [...]

Published
2018

25. 64Cu-SARTATE PET Imaging of Patients with Neuroendocrine Tumors Demonstrates High Tumor Uptake and Retention, Potentially Allowing Prospective Dosimetry for Peptide Receptor Radionuclide Therapy.

Author

Hicks, Rodney J., Jackson, Price, Kong, Grace, Ware, Robert E., Hofman, Michael S., Pattison, David A., Akhurst, Timothy A., Drummond, Elizabeth, Roselt, Peter, Callahan, Jason, Price, Roger, Jeffery, Charmaine M., Hong, Emily, Noonan, Wayne, Herschtal, Alan, Hicks, Lauren J., Hedt, Amos, Harris, Matthew, Paterson, Brett M., and Donnelly, Paul S.

Published
2019
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26. Sinking into the Anthropocene: New Orleans Nature Writing.

Author

Corwin, Hayden, Edwards, Allyssa, Fletcher, Shanté, Hicks, Lauren, Mayer, Ryan, Orellana, Cristian, Ridley, Adrian, and Schaberg, Christopher

Subjects
NATURAL history literature, LANDSCAPES, POTHOLES (Roads), SINKHOLES
Abstract

The article offers information on the nature writing by the students of Loyola University New Orleans. Topics discussed include that how humans are never observing landscapes and other creatures; mentions the line between potholes and sinkholes blurs in this city; and also mentions New Orleans has been shaped by its bumpy, cracking roads.

Published
2019

27. European Transformation Summit: Fresh leadership perspectives.

Author

Gorter, Olivier, Hicks, Lauren, and Theunissen, Rob

Subjects
JOB involvement, LEADERSHIP, BUSINESS enterprises, SENIOR leadership teams
Abstract

(5 pages) B Transformation leaders b and other C-suite executives around the world continue to pursue ambitious transformation programs for reasons that have remained consistent over time: they seek to unlock growth potential, accelerate the rate at which they innovate, improve customer experience, build new capabilities, and compete effectively in the future. Against this backdrop, McKinsey recently convened a group of senior leaders in Europe who are currently engaged in transformation efforts, some on a global scale (see sidebar, "About McKinsey's European Transformation Summit"). When a business need arises, the company makes the decision to either implement an established "catalog solution" for a quick win or run a 16-week digital-strategy initiative to produce a minimum viable product and, ultimately, add it to the catalog of solutions. [Extracted from the article]

Published
2023

28. My College Search.

Author

Hicks, Lauren

Abstract

The author reflects on choosing for the right college. According to the author, it is important for an individual to know what he wants to take before choosing a college. The author considers various factors when choosing a college because it will affect his life in the future. One of these factors is the student-teacher ratio. The author also looks at scholarships and extra curricular activities. The author suggests doing research about different colleges.

Published
1999

29. Temple.

Author

Hicks, Lauren

Abstract

The article presents information on Temple University in Philadelphia, Pennsylvania. The article features the Freshmen Learning Communities which enables freshmen to have their classes together. one of the university's major offerings is the Apollo of Temple, an entertainment, recreation and sports complex. This facility features racquetball courts, an outdoor-multipurpose court area, locker rooms, lounge area, among others.

Published
1999

30. Longitudinal Changes of Depressive Symptoms in Sedentary Women Who Exercised During Pregnancy.

Author

Hicks LE and Yeo S

Abstract

Introduction: Prenatal depression is a common disorder; however, little is known about how depressive symptoms manifest during pregnancy, including when symptoms present and what symptoms are common. This study aimed to better understand prenatal depressive symptoms during pregnancy in the postpartum period, as well as how exercise, such as walking and stretching, can improve depressive symptoms during pregnancy and the postpartum period., Methods: A total of 55 women were assessed using the Beck Depression Inventory-II for depressive symptoms at 16 weeks, 28 weeks, and 2 months postpartum. Sedentary pregnant women at-risk for preeclampsia were randomly assigned to either a stretching or walking group for 40 minutes five times a week from 18 weeks of gestation until birth. The primary analyses were analysis of variance and mixed-effects models., Results: All depressive symptoms decreased throughout pregnancy during the postpartum period, although this trend was not statistically significant. Cognitive-affective and somatic depressive symptoms had different trajectories during pregnancy into the postpartum period, but no significant difference was found. Statistically significant improvements were observed in loss of energy and change in sleeping pattern for the walking and stretching groups., Conclusion: The finding that physical activity improves the depressive symptoms' loss of energy and changes in sleeping patterns during pregnancy aligns with the existing literature, but little research has examined how individual depressive symptoms change throughout pregnancy into the postpartum period. Gaining a better understanding of the trajectories and manifestations of depressive symptoms during pregnancy and the postpartum period is essential for improving detection and treatment practices. Understanding when and how depressive symptoms are present is critical for the clinical diagnosis of this disorder., Competing Interests: No competing financial interests exist., (© Lauren E. Hicks and SeonAe Yeo 2023; Published by Mary Ann Liebert, Inc.)

Published
2023
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31. 64 Cu-SARTATE PET Imaging of Patients with Neuroendocrine Tumors Demonstrates High Tumor Uptake and Retention, Potentially Allowing Prospective Dosimetry for Peptide Receptor Radionuclide Therapy.

Author

Hicks RJ, Jackson P, Kong G, Ware RE, Hofman MS, Pattison DA, Akhurst TA, Drummond E, Roselt P, Callahan J, Price R, Jeffery CM, Hong E, Noonan W, Herschtal A, Hicks LJ, Hedt A, Harris M, Paterson BM, and Donnelly PS

Subjects
Aged, Biological Transport, Female, Humans, Male, Middle Aged, Neuroendocrine Tumors metabolism, Octreotide adverse effects, Octreotide metabolism, Prospective Studies, Radiometry, Radiopharmaceuticals adverse effects, Safety, Neuroendocrine Tumors diagnostic imaging, Neuroendocrine Tumors radiotherapy, Octreotide analogs & derivatives, Positron Emission Tomography Computed Tomography, Radiopharmaceuticals metabolism, Receptors, Peptide metabolism
Abstract

Imaging of somatostatin receptor expression is an established technique for staging of neuroendocrine neoplasia and determining the suitability of patients for peptide receptor radionuclide therapy. PET/CT using 68 Ga-labeled somatostatin analogs is superior to earlier agents, but the rapid physical decay of the radionuclide poses logistic and regulatory challenges. 64 Cu has attractive physical characteristics for imaging and provides a diagnostic partner for the therapeutic radionuclide 67 Cu. Based on promising preclinical studies, we have performed a first-time-in-humans trial of 64 Cu-MeCOSar-Tyr 3 -octreotate ( 64 Cu-SARTATE) to assess its safety and ability to localize disease at early and late imaging time-points. Methods: In a prospective trial, 10 patients with known neuroendocrine neoplasia and positive for uptake on 68 Ga-DOTA-octreotate ( 68 Ga-DOTATATE) PET/CT underwent serial PET/CT imaging at 30 min, 1 h, 4 h, and 24 h after injection of 64 Cu-SARTATE. Adverse reactions were recorded, and laboratory testing was performed during infusion and at 1 and 7 d after imaging. Images were analyzed for lesion and normal-organ uptake and clearance to assess lesion contrast and perform dosimetry estimates. Results: 64 Cu-SARTATE was well tolerated during infusion and throughout the study, with 3 patients experiencing mild infusion-related events. High lesion uptake and retention were observed at all imaging time-points. There was progressive hepatic clearance over time, providing the highest lesion-to-liver contrast at 24 h. Image quality remained high at this time. Comparison of 64 Cu-SARTATE PET/CT obtained at 4 h to 68 Ga-DOTATATE PET/CT obtained at 1 h indicated comparable or superior lesion detection in all patients, especially in the liver. As expected, the highest early physiologic organ uptake was in the kidneys, liver, and spleen. Conclusion: 64 Cu-SARTATE is safe and has excellent imaging characteristics. High late-retention in tumor and clearance from the liver suggest suitability for diagnostic studies and for prospective dosimetry for 67 Cu-SARTATE peptide receptor radionuclide therapy, and the half-life of 64 Cu would also facilitate good-manufacturing-practice production and distribution to sites without access to 68 Ga., (© 2019 by the Society of Nuclear Medicine and Molecular Imaging.)

Published
2019
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