Search

Your search keyword '"Hickman, Peter E."' showing total 331 results
Start Over Author "Hickman, Peter E."
331 results on '"Hickman, Peter E."'

10. Oral glucose tolerance test to diagnose gestational diabetes mellitus: Impact of variations in specimen handling

Author

Jamieson, Emma L, primary, Dimeski, Goce, additional, Flatman, Robert, additional, Hickman, Peter E, additional, Ross Dallas Jones, Graham, additional, V Marley, Julia, additional, David McIntyre, H., additional, McNeil, Alan R, additional, Nolan, Christopher J, additional, Potter, Julia M, additional, Sweeting, Arianne, additional, Ward, Peter, additional, Williams, Paul, additional, and Rita Horvath, Andrea, additional

Published
2022
Full Text
View/download PDF

23. Troponins in myocardial infarction and injury.

Author

Potter, Julia M., Hickman, Peter E., and Cullen, Louise

Subjects
*MYOCARDIAL infarction, *MYOCARDIAL injury, *ACUTE coronary syndrome, *MYOCARDIUM
Abstract

Troponins are proteins that are integral components of the contractile mechanism of muscle, including cardiac muscle. Cardiac troponins I and T can be detected in the blood of most people after puberty, at concentrations reflecting cardiac mass, sex and age. Current laboratory assays are approximately 1000 times more sensitive than those used previously. They also have higher sensitivity than point-of-care assays. The measurement of cardiac troponins is used primarily to assist in the diagnosis or exclusion of myocardial injury. Serial tests in acute coronary syndrome are guided by the Universal Definition of Myocardial Infarction. [ABSTRACT FROM AUTHOR]

Published
2022
Full Text
View/download PDF

39. Plasma homocysteine levels in indigenous Australians

Author

Shaw, Joanne T.E., McWhinney, Brett, Tate, Jill R., Kesting, Janine B., Marczak, Maureen, Purdie, David, Gibbs, Harry, Cameron, Donald P., and Hickman, Peter E.

Subjects
Homocysteine -- Demographic aspects, Coronary heart disease -- Risk factors, Peripheral vascular diseases -- Risk factors, Indigenous peoples -- Australia, Australian aborigines -- Health aspects, Health
Abstract

Elevated homocysteine levels in the blood is prevalent among indigenous Australians. High plasma homocysteine is a risk factor for coronary artery and vascular disease. Researchers tested 365 Australians of indigenous races, and found that 24% had homocysteine levels considered to be unhealthy. Elevated homocysteine was more common in men, and associated with smoking, vascular disease, folate and vitamin B12 deficiency, and the antidiabetes drug metformin. Health education aimed at reducing cardiac risk factors and improving nutrition among indigenous cultures is indicated.

Published
1999

47. Harmonising Reference Intervals for Three Calculated Parameters used in Clinical Chemistry

Author

Hughes, David, Koerbin, Gus, Potter, Julia M, Glasgow, Nicholas, West, Nic, Abhayaratna, Walter P, Cavanaugh, Juleen, Armbruster, David, and Hickman, Peter E

Subjects
Mini-Review
Abstract

For more than a decade there has been a global effort to harmonise all phases of the testing process, with particular emphasis on the most frequently utilised measurands. In addition, it is recognised that calculated parameters derived from these measurands should also be a target for harmonisation. Using data from the Aussie Normals study we report reference intervals for three calculated parameters: serum osmolality, serum anion gap and albumin-adjusted serum calcium. The Aussie Normals study was an a priori study that analysed samples from 1856 healthy volunteers. The nine analytes used for the calculations in this study were measured on Abbott Architect analysers. The data demonstrated normal (Gaussian) distributions for the albumin-adjusted serum calcium, the anion gap (using potassium in the calculation) and the calculated serum osmolality (using both the Bhagat et al. and Smithline and Gardner formulae). To assess the suitability of these reference intervals for use as harmonised reference intervals, we reviewed data from the Royal College of Pathologists of Australasia/Australasian Association of Clinical Biochemists (RCPA/AACB) bias survey. We conclude that the reference intervals for the calculated serum osmolality (using the Smithline and Gardner formulae) may be suitable for use as a common reference interval. Although a common reference interval for albumin-adjusted serum calcium may be possible, further investigations (including a greater range of albumin concentrations) are needed. This is due to the bias between the Bromocresol Green (BCG) and Bromocresol Purple (BCP) methods at lower serum albumin concentrations. Problems with the measurement of Total CO2 in the bias survey meant that we could not use the data for assessing the suitability of a common reference interval for the anion gap. Further study is required.

Published
2016

Catalog

Books, media, physical & digital resources
See catalog results