156 results on '"Heyworth, C M"'
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2. The Role of Growth Factors in Self-Renewal and Differentiation of Haemopoietic Stem Cells
3. The Role of Haemopoietic Cell Growth Factor (Interleukin 3) in the Development of Haemopoietic Cells
4. Abl protein kinase abrogates the response of multipotent haemopoietic cells to the growth inhibitor macrophage inflammatory protein-1 alpha
5. Growth factors and the molecular control of haematopoiesis
6. Effect of interleukins on the proliferation and survival of B cell chronic lymphocytic leukaemia cells
7. Stromal Cells in Haemopoiesis
8. An activated protein kinase C alpha gives a differentiation signal for hematopoietic progenitor cells and mimicks macrophage colony-stimulating factor-stimulated signaling events
9. Investigation of the molecular mechanisms underlying growth factor synergy:the role of ERK 2 activation in synergy
10. Ectopic interleukin-5 receptor expression promotes proliferation without development in a multipotent hematopoietic cell line
11. INVESTIGATION OF THE MOLECULAR MECHANISMS BY WHICH SCF SYNERGISTICALLY PROMOTES THE EFFECTS OF CYTOKINES ON FDCP-MIX A4 CELLS
12. Macrophage inflammatory protein-1 alpha mediated growth inhibition in a haemopoietic stem cell line is associated with inositol 1,4,5 triphosphate generation
13. Cytokine-mediated protein kinase C activation is a signal for lineage determination in bipotential granulocyte macrophage colony-forming cells
14. Haemopoietic stem cell development to neutrophils is associated with subcellular redistribution and differential expression of protein kinase C subspecies
15. Differential Response of CD34 + Cells Isolated from Cord Blood and Bone Marrow to MIP‐1α and the Expression of MIP‐1α Receptors on These Immature Cells
16. Investigation of the Molecular Mechanisms Underlying Growth Factor Synergy: The Role of ERK 2 Activation in Synergy
17. Effects of interleukins on the proliferation and survival of chronic lymphocytic leukaemia cells.
18. IL-4 promotes macrophage development by rapidly stimulating lineage restriction of bipotent granulocyte-macrophage colony-forming cells.
19. Cytokine-mediated protein kinase C activation is a signal for lineage determination in bipotential granulocyte macrophage colony-forming cells.
20. Development of Multipotential Haemopoietic Stem Cells to Neutrophils is Associated with Increased Expression of Receptors for Granulocyte Macrophage Colony-Stimulating Factor: Altered Biological Responses to GM-CSF during Development
21. The Role of Hemopoietic Growth Factors in Self-Renewal and Differentiation of IL-3-Dependent Multipotential Stem Cells
22. The biochemistry and biology of the myeloid haemopoietic cell growth factors
23. NOD/SCID repopulating cells but not LTC-IC are enriched in human CD34+ cells expressing the CCR1 chemokine receptor.
24. Characterisation of the differential response of normal and CML haemopoietic progenitor cells to macrophage inflammatory protein-1alpha.
25. Recombinant human interleukin 4 (IL-4) given as daily subcutaneous injections--a phase I dose toxicity trial.
26. Proliferation and differentiation of murine haemopoietic progenitor cells in stroma-free culture in the presence of metabolites of chlorinated pesticides
27. Identification of amino acid residues critical for aggregation of human CC chemokines macrophage inflammatory protein (MIP)-1alpha, MIP-1beta, and RANTES. Characterization of active disaggregated chemokine variants.
28. Insulin inhibits the cholera-toxin-catalysed ribosylation of a Mr-25000 protein in rat liver plasma membranes
29. Islet-activating protein blocks glucagon desensitization in intact hepatocytes
30. An assessment of the ability of insulin-stimulated cyclic AMP phosphodiesterase to decrease hepatocyte intracellular cyclic AMP concentrations
31. N 6-(Phenylisopropyl)adenosine prevents glucagon both blocking insulin's activation of the plasma-membrane cyclic AMP phosphodiesterase and uncoupling hormonal stimulation of adenylate cyclase activity in hepatocytes
32. Insulin exerts actions through a distinct species of guanine nucleotide regulatory protein: inhibition of adenylate cyclase
33. Challenge of hepatocytes by glucagon triggers a rapid modulation of adenylate cyclase activity in isolated membranes
34. Insulin and glucagon regulate the activation of two distinct membrane-bound cyclic AMP phosphodiesterases in hepatocytes
35. Phorbol esters activate protein kinase c and glucose transport and can replace the requirement for growth factor in interleukin-3-dependent multipotent stem cells
36. The action of islet activating protein (pertussis toxin) on insulin's ability to inhibit adenylate cyclase and activate cyclic AMP phosphodiesterases in hepatocytes
37. Haemopoietic stem cell development to neutrophils is associated with subcellular redistribution and differential expression of protein kinase C subspecies
38. Interleukin-3-stimulated haemopoietic stem cell proliferation. Evidence for activation of protein kinase C and Na+/H+ exchange without inositol lipid hydrolysis
39. The binding of human liver acid β-galactosidase to wheat-germ lectin is influenced by aggregation state of the enzyme
40. The stability and aggregation properties of human liver acid β-d-galactosidase
41. CCR1 chemokine receptor expression isolates erythroid from granulocyte-macrophage progenitors
42. IL-4 promotes macrophage development by rapidly stimulating lineage restriction of bipotent granulocyte-macrophage colony-forming cells
43. Retroviral transfer and expression of human MDR-1 in a murine haemopoietic stem cell line does not alter factor dependence, growth or differentiation characteristics.
44. Lineage restriction of the RARalpha gene expression in myeloid differentiation.
45. CCR1 chemokine receptor expression isolates erythroid from granulocyte-macrophage progenitors.
46. Differentiating embryonal stem cells are a rich source of haemopoietic gene products and suggest erythroid preconditioning of primitive haemopoietic stem cells.
47. Cord blood G(0) CD34+ cells have a thousand-fold higher capacity for generating progenitors in vitro than G(1) CD34+ cells.
48. Transforming growth factor-beta 1 induces apoptosis independently of p53 and selectively reduces expression of Bcl-2 in multipotent hematopoietic cells.
49. A transient assay for regulatory gene function in haemopoietic progenitor cells.
50. Altered development and cytokine responses of myeloid progenitors in the absence of transcription factor, interferon consensus sequence binding protein.
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