1. MR-guided breast biopsy at 3T: diagnostic yield of large core needle biopsy compared with vacuum-assisted biopsy
- Author
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Hester N. van Hall, Jeroen Veltman, Ritse M. Mann, Carla Boetes, Roel Mus, Jelle O. Barentsz, Carla Meeuwis, Beeldvorming, and RS: GROW - School for Oncology and Reproduction
- Subjects
Breast biopsy ,Adult ,medicine.medical_specialty ,Vacuum ,Biopsy ,Aetiology, screening and detection [ONCOL 5] ,Magnetic Resonance Imaging, Interventional ,Breast cancer ,Energy and redox metabolism Aetiology, screening and detection [NCMLS 4] ,Neoplasms ,medicine ,Humans ,Mass Screening ,Radiology, Nuclear Medicine and imaging ,Breast ,High field ,Mass screening ,Neuroradiology ,Aged ,medicine.diagnostic_test ,integumentary system ,business.industry ,Ultrasound ,Biopsy, Needle ,Reproducibility of Results ,Interventional radiology ,General Medicine ,Equipment Design ,Middle Aged ,medicine.disease ,Magnetic Resonance Imaging ,Treatment Outcome ,Radiology Nuclear Medicine and imaging ,Vacuum-Assisted Biopsy ,Female ,Radiology ,business ,MRI - Abstract
Item does not contain fulltext OBJECTIVE: The purpose of this study was to evaluate two MR-guided biopsy techniques at 3 T, large core needle breast biopsy (LCNB) and vacuum-assisted breast biopsy (VAB) and to compare the diagnostic yield and rate of complications to determine the optimal biopsy technique at 3 T. METHODS: 55 LCNB and 64 VAB were consecutively performed. Benign biopsy results were verified by retrospective correlation of histology, with pre-interventional, post-interventional MRI studies and follow-up and were classified as representative or non-representative. Time to follow-up was up to 2 years for the considered non-representative benign lesions. Statistical analysis was performed using the Chi-squared test. RESULTS: LCNB was technically successful in 100% of patients (55/55) and VAB in 98% of patients (63/64). Histopathological analysis resulted in 45 (82%) benign, 3 (5%) high-risk and 7 (13%) malignant lesions for LCNB and 43 (67%) benign, 3 (5%) high-risk and 18 (28%) malignant lesions. Distribution was significantly different (p < 0.001), favouring VAB over LCNB. CONCLUSION: Because of the substantially higher diagnostic yield and certainty of a benign diagnosis, VAB is the optimal biopsy technique at 3 T. LCNB should be considered when VAB is not feasible. 01 februari 2012
- Published
- 2011