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5. Upfront resection versus no resection of the primary tumor in patients with synchronous metastatic colorectal cancer: the randomized phase III CAIRO4 study conducted by the Dutch Colorectal Cancer Group and the Danish Colorectal Cancer Group

13. Tenascin-W Is a Novel Stromal Marker in Biliary Tract Cancers

15. Ferric carboxymaltose infusion versus oral iron supplementation for preoperative iron deficiency anaemia in patients with colorectal cancer (FIT): a multicentre, open-label, randomised, controlled trial

16. After/Lives: Insights from the COVID-19 Pandemic for Gay Neighborhoods

17. Understanding Generation Gaps in LGBTQ+ Communities: Perspectives About Gay Neighborhoods Among Heteronormative and Homonormative Generational Cohorts

18. Who Are the People in Your Gayborhood? Understanding Population Change and Cultural Shifts in LGBTQ+ Neighborhoods

22. Comparing Isolated Thumb Force Generation, Wrist Rotation, and Clinical Measurements in Healthy and Osteoarthritic Individuals before and after Surgery.

24. Effects of new construction and renovation on ethnic and social mixing in apartment buildings in Estonia

26. Incomplete Service Networks in Enduring Socialist Housing Estates: Retrospective Evidence from Local Centres in Estonia

27. Architectural Transcendence in Soviet-Era Housing: Evidence from Socialist Residential Districts in Tallinn, Estonia

28. Modernist Housing Estates in the Baltic Countries: Formation, Current Challenges and Future Prospects

29. A conserved chronobiological complex timesC. elegans development

34. Contributors

37. BANP opens chromatin and activates CpG-island-regulated genes

42. Going dark: the post-pandemic transformation of the metropolitan retail landscape

43. Adjuvant hyperthermic intraperitoneal chemotherapy in patients with locally advanced colon cancer (COLOPEC): a multicentre, open-label, randomised trial

47. On the Topology of Weakly and Strongly Separated Set Complexes

48. Thermal evolution of massive compact objects with dense quark cores

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