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1. Quality indicators in intensive care medicine for Germany – fourth edition 2022

Author

Kumpf, Oliver, Assenheimer, Markus, Bloos, Frank, Brauchle, Maria, Braun, Jan-Peter, Brinkmann, Alexander, Czorlich, Patrick, Dame, Christof, Dubb, Rolf, Gahn, Georg, Greim, Clemens-A., Gruber, Bernd, Habermehl, Hilmar, Herting, Egbert, Kaltwasser, Arnold, Krotsetis, Sabine, Kruger, Bastian, Markewitz, Andreas, Marx, Gernot, Muhl, Elke, Nydahl, Peter, Pelz, Sabrina, Sasse, Michael, Schaller, Stefan J., Schäfer, Andreas, Schürholz, Tobias, Ufelmann, Marina, Waydhas, Christian, Weimann, Jörg, Wildenauer, René, Wöbker, Gabriele, Wrigge, Hermann, and Riessen, Reimer

Subjects
quality management, intensive care medicine, quality indicators, peer review, Medicine
Abstract

The measurement of quality indicators supports quality improvement initiatives. The German Interdisciplinary Society of Intensive Care Medicine (DIVI) has published quality indicators for intensive care medicine for the fourth time now. After a scheduled evaluation after three years, changes in several indicators were made. Other indicators were not changed or only minimally. The focus remained strongly on relevant treatment processes like management of analgesia and sedation, mechanical ventilation and weaning, and infections in the ICU. Another focus was communication inside the ICU. The number of 1ndicators remained the same. The development method was more structured and transparency was increased by adding new features like evidence levels or author contribution and potential conflicts of interest. These quality indicators should be used in the peer review in intensive care, a method endorsed by the DIVI. Other forms of measurement and evaluation are also reasonable, for example in quality management. This fourth edition of the quality indicators will be updated in the future to reflect the recently published recommendations on the structure of intensive care units by the DIVI.

Published
2023
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5. Early postnatal high-dose fat-soluble enteral vitamin A supplementation for moderate or severe bronchopulmonary dysplasia or death in extremely low birthweight infants (NeoVitaA): a multicentre, randomised, parallel-group, double-blind, placebo-controlled, investigator-initiated phase 3 trial

Author

Schuler, Rahel, Kampschulte, Birgit, Schmidt, Annesuse, Atanasov, Svilen, Dzietko, Mark, Prager, Sebastian, Bialas, Ioana, Kramps, Petra, Beckmann, Sarah, Seidenberg, Jürgen, Majosthusmann, Katja, Potratz, Jenny, van den Heuvel, Alijda, Tekaat, Maria, Dettmers, Susanne, Unterweger, Marie-Therese, Nowak, Heike, Möller, Jens, Thome, Ulrich, Arand, Jörg, Luger, Beate, Maiwald, Christian A, Heideking, Martin, Heckmann, Matthias, Keller-Wacherbauer, Annette, Michel, Holger, Karen, Tanja, Schmid, Anna, Pellkofer, Yasmin, Griesmaier, Elke, Genzel-Boroviczeny, Orsolya, Mata Fernandez, Raquel, Avenarius, Stefan, Czoske, Andrea, Block, Christoph, Schwarz, Simone, Jenke, Andreas, Grass, Tamara, Kuntz, Martin, Fahlbusch, Fabian, Pöschl, Johannes, Metzger, Jule, Ronellenfitsch, Sebastian, Schaible, Thomas, Reinhard, Julia, Trepels-Kottek, Sonja, Bauer, Jacqueline, Herting, Egbert, Henn, Wolfram, Laupert, Annette, Jathe, Rebecca, Meyer, Sascha, Bay, Johannes, Franz, Axel R, Ehrhardt, Harald, Klein, Lars, Petzinger, Jutta, Binder, Christoph, Kirschenhofer, Susanne, Stein, Anja, Hüning, Britta, Heep, Axel, Cloppenburg, Eva, Muyimbwa, Julia, Ott, Torsten, Sandkötter, Julia, Teig, Norbert, Wiegand, Susanne, Schroth, Michael, Kick, Andrea, Wurm, Donald, Gebauer, Corinna, Linnemann, Knud, Kittel, Jochen, Wieg, Christian, Kiechl-Kohlendorfer, Ursula, Schmidt, Susanne, Böttger, Ralf, Thomas, Wolfgang, Brevis Nunez, Francisco, Stockmann, Antje, Kriebel, Thomas, Müller, Andreas, Klotz, Daniel, Morhart, Patrick, Nohr, Donatus, Biesalski, Hans Konrad, Giannopoulou, Eleni Z, Hilt, Susanne, Poryo, Martin, Wagenpfeil, Stefan, Haiden, Nadja, Ruckes, Christian, Ehrlich, Anne, and Gortner, Ludwig

Published
2024
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7. Respiratory Syncytial Virus Prophylaxis With Palivizumab Is Not Associated With Improved Lung Function in Infants of Very Low Birth Weight at Early School Age

Author

Fortmann, Ingmar, Dammann, Marie-Theres, Humberg, Alexander, Kraft, Hannah, Herz, Alexander, Hanke, Kathrin, Faust, Kirstin, Ricklefs, Isabell, Zemlin, Michael, Liese, Johannes, Engels, Geraldine, Härtel, Christoph, Fortmann-Grote, Carsten, Kopp, Matthias Volkmar, Brinkmann, Folke, Herting, Egbert, Göpel, Wolfgang, and Stichtenoth, Guido

Published
2024
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13. Higher awakening threshold of preterm infants in prone position may be a risk factor for SIDS.

Author

Ikels, Alina Kristin, Herting, Egbert, and Stichtenoth, Guido

Subjects
*PREMATURE infants, *PATIENT positioning, *SUDDEN infant death syndrome, *SUPINE position, *SLEEP positions
Abstract

Aim: The supine sleeping position in the prevention of sudden infant death syndrome in preterm infants is poorly understood. We aimed to investigate the effect of sleep posture on cardiorespiratory parameters and movement patterns in preterm infants close to discharge. Methods: This observational study included neonates born in 2022 at the University Hospital Schleswig‐Holstein, Lübeck, Germany. Motion sensor data, heart rate, respiratory rate and oxygen saturation were recorded for infants with postconceptional age 35–37 weeks during sleep in the prone and supine positions. Results: We recorded data from 50 infants, born at 31 (24–35) weeks of gestation (mean(range)), aged 5.2 ± 3.7 weeks (mean ± SD), of whom 48% were female. Five typical movement patterns were identified. In the prone position, the percentage of calm, regular breathing was higher and active movement was less frequent when compared to the supine position. The percentage of calm irregular breathing, number of apnoeas, bradycardias, desaturations and vital sign changes were not influenced by position. Conclusion: The prone position seems to be associated with a higher arousal threshold. The supine position appears advantageous for escape from life‐threatening situations such as sudden infant death syndrome. [ABSTRACT FROM AUTHOR]

Published
2024
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16. Early postnatal high-dose fat-soluble enteral vitamin A supplementation for moderate or severe bronchopulmonary dysplasia or death in extremely low birthweight infants (NeoVitaA): a multicentre, randomised, parallel-group, double-blind, placebo-controlled, investigator-initiated phase 3 trial

Author

Meyer, Sascha, Bay, Johannes, Franz, Axel R, Ehrhardt, Harald, Klein, Lars, Petzinger, Jutta, Binder, Christoph, Kirschenhofer, Susanne, Stein, Anja, Hüning, Britta, Heep, Axel, Cloppenburg, Eva, Muyimbwa, Julia, Ott, Torsten, Sandkötter, Julia, Teig, Norbert, Wiegand, Susanne, Schroth, Michael, Kick, Andrea, Wurm, Donald, Gebauer, Corinna, Linnemann, Knud, Kittel, Jochen, Wieg, Christian, Kiechl-Kohlendorfer, Ursula, Schmidt, Susanne, Böttger, Ralf, Thomas, Wolfgang, Brevis Nunez, Francisco, Stockmann, Antje, Kriebel, Thomas, Müller, Andreas, Klotz, Daniel, Morhart, Patrick, Nohr, Donatus, Biesalski, Hans Konrad, Giannopoulou, Eleni Z, Hilt, Susanne, Poryo, Martin, Wagenpfeil, Stefan, Haiden, Nadja, Ruckes, Christian, Ehrlich, Anne, Gortner, Ludwig, Schuler, Rahel, Kampschulte, Birgit, Schmidt, Annesuse, Atanasov, Svilen, Dzietko, Mark, Prager, Sebastian, Bialas, Ioana, Kramps, Petra, Beckmann, Sarah, Seidenberg, Jürgen, Majosthusmann, Katja, Potratz, Jenny, van den Heuvel, Alijda, Tekaat, Maria, Dettmers, Susanne, Unterweger, Marie-Therese, Nowak, Heike, Möller, Jens, Thome, Ulrich, Arand, Jörg, Luger, Beate, Maiwald, Christian A, Heideking, Martin, Heckmann, Matthias, Keller-Wacherbauer, Annette, Michel, Holger, Karen, Tanja, Schmid, Anna, Pellkofer, Yasmin, Griesmaier, Elke, Genzel-Boroviczeny, Orsolya, Mata Fernandez, Raquel, Avenarius, Stefan, Czoske, Andrea, Block, Christoph, Schwarz, Simone, Jenke, Andreas, Grass, Tamara, Kuntz, Martin, Fahlbusch, Fabian, Pöschl, Johannes, Metzger, Jule, Ronellenfitsch, Sebastian, Schaible, Thomas, Reinhard, Julia, Trepels-Kottek, Sonja, Bauer, Jacqueline, Herting, Egbert, Henn, Wolfram, Laupert, Annette, and Jathe, Rebecca

Abstract

Vitamin A plays a key role in lung development, but there is no consensus regarding the optimal vitamin A dose and administration route in extremely low birthweight (ELBW) infants. We aimed to assess whether early postnatal additional high-dose fat-soluble enteral vitamin A supplementation versus placebo would lower the rate of moderate or severe bronchopulmonary dysplasia or death in ELBW infants receiving recommended basic enteral vitamin A supplementation.

Published
2024
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17. Perinatal Outcomes of Immigrant Mothers and Their Infants Born Very Preterm across Germany.

Author

Hüning, Britta M., Jaekel, Julia, Jaekel, Nils, Göpel, Wolfgang, Herting, Egbert, Felderhoff-Müser, Ursula, Spiegler, Juliane, and Härtel, Christoph

Subjects
PREECLAMPSIA diagnosis, IMMIGRANTS, MATERNAL health services, RESEARCH funding, LOGISTIC regression analysis, PREGNANCY outcomes, DESCRIPTIVE statistics, INFECTION, LONGITUDINAL method, ODDS ratio, PSYCHOLOGY of mothers, RESEARCH, CONFIDENCE intervals, DATA analysis software, AMNIOTIC liquid, HEALTH equity, EDUCATIONAL attainment, COMMUNICATION barriers
Abstract

Background: In Germany, more than 40% of infants are born to immigrant parents. Increased survival rates of very preterm (below 32 weeks gestation at birth; VP) infants have not resulted in equally improved life chances and quality of life. More information on perinatal variations in outcomes according to social inequalities, migration background, and language barriers is needed. We tested whether mothers' immigrant status and language barriers are associated with perinatal health and short-term neonatal outcomes. Methods: The data are from the national multi-centre German Neonatal Network (GNN) cohort, including VP births from 2009 onwards. In total, 3606 (n = 1738 female) children were assessed, and 919 (n = 449 female) of these children had immigrant backgrounds. Immigrant status was operationalised as a binary variable based on the children's mothers' countries of birth (born in Germany vs. foreign-born). Self-reported home language (L1) was used to calculate the average linguistic distance to German as one continuous variable. Results: Mixed-effects models showed that two out of fourteen effects of interest survived the adjustment for known confounders and accounting for the nestedness of data within birth hospitals. Linguistic distance from mothers' L1s to German was independently associated with diagnoses of preeclampsia (OR = 1.01, 95% CI = [1.00, 1.01]). Infants of foreign-born mothers had higher odds for amniotic infection syndrome (AIS; OR = 1.45 [1.13, 1.86]) than infants of German mothers. Conclusions: Our findings from this large multi-centre longitudinal cohort of VP-born children indicate that maternal immigrant status and language barriers have limited impact on perinatal health and severe neonatal outcomes. This suggests that, regardless of background or language skills, there may be few inequalities in the perinatal health of pregnant women and their newborn preterm infants. [ABSTRACT FROM AUTHOR]

Published
2024
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21. Respiratory Syncytial Virus Prophylaxis With Palivizumab Is Not Associated With Improved Lung Function in Infants of Very Low Birth Weight at Early School Age

Author

Fortmann, Ingmar, primary, Dammann, Marie-Theres, additional, Humberg, Alexander, additional, Kraft, Hannah, additional, Herz, Alexander, additional, Hanke, Kathrin, additional, Faust, Kirstin, additional, Ricklefs, Isabell, additional, Zemlin, Michael, additional, Liese, Johannes, additional, Engels, Geraldine, additional, Härtel, Christoph, additional, Fortmann-Grote, Carsten, additional, Kopp, Matthias Volkmar, additional, Brinkmann, Folke, additional, Herting, Egbert, additional, Göpel, Wolfgang, additional, and Stichtenoth, Guido, additional

Published
2023
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24. Prävention und Therapie der Frühgeburt : Leitlinie der DGGG, OEGGG und SGGG (S2k-Level, AWMF-Registernummer 015/025, September 2022) – Teil 1 mit Empfehlungen zur Epidemiologie, Ätiologie, Prädiktion, primären und sekundären Prävention der Frühgeburt

Author

Berger, Richard, Abele, Harald, Bahlmann, Franz, Doubek, Klaus, Felderhoff-Müser, Ursula, Fluhr, Herbert, Garnier, Yves, Grylka-Baeschlin, Susanne, Hayward, Aurelia, Helmer, Hanns, Herting, Egbert, Hoopmann, Markus, Hösli, Irene, Hoyme, Udo, Kunze, Mirjam, Kuon, Ruben-H., Kyvernitakis, Ioannis, Lütje, Wolf, Mader, Silke, Maul, Holger, Mendling, Werner, Mitschdörfer, Barbara, Nothacker, Monika, Olbertz, Dirk, Ramsell, Andrea, Rath, Werner, Roll, Claudia, Schlembach, Dietmar, Schleußner, Ekkehard, Schütz, Florian, Seifert-Klauss, Vanadin, Stubert, Johannes, and Surbek, Daniel

Subjects
Vorzeitige Wehentätigkeit, Preterm labor, Medizin, Obstetrics and Gynecology, Preterm birth, 618: Geburtsmedizin und Hebammenarbeit, Guideline, Frühgeburt, Früher vorzeitiger Blasensprung, Cervical insufficiency, Preterm premature rupture of membranes, Zervixinsuffizienz, Maternity and Midwifery, Leitlinie
Abstract

Artikel in mehreren Sprachen: Deutsch und Englisch Aim: This revised guideline was coordinated by the German Society for Gynecology and Obstetrics (DGGG), the Austrian Society for Gynecology and Obstetrics (OEGGG) and the Swiss Society for Gynecology and Obstetrics (SGGG). It aims to improve the prediction, prevention, and management of preterm birth, based on evidence from the current literature, the experience of members of the guidelines commission, and the viewpoint of self-help organizations. Methods: The members of the contributing professional societies and organizations developed recommendations and statements based on international literature. The recommendations and statements were presented and adopted using a formal process (structured consensus conferences with neutral moderation, written Delphi vote). Recommendations: Part 1 of this short version of the guideline presents statements and recommendations on the epidemiology, etiology, prediction, and primary and secondary prevention of preterm birth. Ziel: Überarbeitete Leitlinie der Deutschen Gesellschaft für Gynäkologie und Geburtshilfe (DGGG), der Österreichischen Gesellschaft für Gynäkologie und Geburtshilfe (OEGGG) und der Schweizerischen Gesellschaft für Gynäkologie und Geburtshilfe (SGGG). Ziel der Leitlinie ist es, die Prädiktion, die Prävention und das Management der Frühgeburt anhand der aktuellen Literatur, der Erfahrung der Mitglieder der Leitlinienkommission einschließlich der Sicht der Selbsthilfe evidenzbasiert zu verbessern. Methoden: Anhand der internationalen Literatur entwickelten die Mitglieder der beteiligten Fachgesellschaften und Organisationen zahlreiche Empfehlungen und Statements. Diese wurden in einem formalen Prozess (strukturierte Konsensuskonferenzen mit neutraler Moderation, schriftliche Delphi-Abstimmung) verabschiedet. Empfehlungen: Der Teil 1 dieser Kurzversion der Leitlinie zeigt Statements und Empfehlungen zur Epidemiologie, Ätiologie, der Prädiktion sowie der primären und sekundären Prävention der Frühgeburt.

Published
2023

27. Repaglinide versus insulin for newly diagnosed diabetes in patients with cystic fibrosis: a multicentre, open-label, randomised trial

Author

Staden, Ute, Claßen, Martin, Schuster, Antje, Mellies, Uwe, Posselt, Hans-Georg, Wiebel, Matthias, Rietschel, Ernst, Stern, Martin, Teschler, Helmut, Smaczny, Christina, Köhnlein, Thomas, Wienhausen-Wilke, Vera, Claaß, Andreas, Biedermann, Thomas, Dockter, Gerd, Köster, Holger, Hebestreit, Helge, Ballke, Ernst-Hinrich, Heuer, Hans-Eberhard, Kamin, Wolfgang, Küster, Peter, Szczepanski, Rüdiger, Keller, Klaus-Michael, Generlich, Horst, Bresser, Hans-Georg, Kopp, Matthias, Herting, Egbert, Feickert, Hans-Joachim, Hautz, Jürgen, Schilling, Birgit, Meyer, Egbert, Mall, Marcus A, Wiebicke, Wolfram, Tegtmeyer, Friedrich-Karl, Honer, Marguerite, Mosnier-Pudar, Helen, Lenoir, Gérard, Robert, Jean-Jacques, Kessler, Laurence, Weiss, Laurence, Nove-Josserand, Raphaële, Vantyghem, Marie-Christine, Munck, Anne, Wizla, Nathalie, Leroy, Sylvie, Loeuille, Guy-André, Serreau, Raphaël, Aissat, Fawzia, Thalhammer, Gabriela H, Huttegger, Isidor, Eichler, Irmgard, Götz, Manfred, Ballmann, Manfred, Hubert, Dominique, Assael, Baroukh M, Staab, Doris, Hebestreit, Alexandra, Naehrlich, Lutz, Nickolay, Tanja, Prinz, Nicole, and Holl, Reinhard W

Published
2018
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28. Correction: Prevention and Therapy of Preterm Birth. Guideline of the DGGG, OEGGG and SGGG (S2k Level, AWMF Registry Number 015/025, September 2022) – Part 2 with Recommendations on the Tertiary Prevention of Preterm Birth and on the Management of Preterm Premature Rupture of Membranes

Author

Berger, Richard, additional, Abele, Harald, additional, Bahlmann, Franz, additional, Doubek, Klaus, additional, Felderhoff-Müser, Ursula, additional, Fluhr, Herbert, additional, Garnier, Yves, additional, Grylka-Baeschlin, Susanne, additional, Hayward, Aurelia, additional, Helmer, Hanns, additional, Herting, Egbert, additional, Hoopmann, Markus, additional, Hösli, Irene, additional, Hoyme, Udo, additional, Kunze, Mirjam, additional, Kuon, Ruben-J., additional, Kyvernitakis, Ioannis, additional, Lütje, Wolf, additional, Mader, Silke, additional, Maul, Holger, additional, Mendling, Werner, additional, Mitschdörfer, Barbara, additional, Nothacker, Monika, additional, Olbertz, Dirk, additional, Ramsell, Andrea, additional, Rath, Werner, additional, Roll, Claudia, additional, Schlembach, Dietmar, additional, Schleußner, Ekkehard, additional, Schütz, Florian, additional, Seifert-Klauss, Vanadin, additional, Stubert, Johannes, additional, and Surbek, Daniel, additional

Published
2023
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29. Correction: Prevention and Therapy of Preterm Birth. Guideline of the DGGG, OEGGG and SGGG (S2k-Level, AWMF Registry Number 015/025, September 2022) – Part 1 with Recommendations on the Epidemiology, Etiology, Prediction, Primary and Secondary Prevention of Preterm Birth

Author

Berger, Richard, additional, Abele, Harald, additional, Bahlmann, Franz, additional, Doubek, Klaus, additional, Felderhoff-Müser, Ursula, additional, Fluhr, Herbert, additional, Garnier, Yves, additional, Grylka-Baeschlin, Susanne, additional, Hayward, Aurelia, additional, Helmer, Hanns, additional, Herting, Egbert, additional, Hoopmann, Markus, additional, Hösli, Irene, additional, Hoyme, Udo, additional, Kunze, Mirjam, additional, Kuon, Ruben-J., additional, Kyvernitakis, Ioannis, additional, Lütje, Wolf, additional, Mader, Silke, additional, Maul, Holger, additional, Mendling, Werner, additional, Mitschdörfer, Barbara, additional, Nothacker, Monika, additional, Olbertz, Dirk, additional, Ramsell, Andrea, additional, Rath, Werner, additional, Roll, Claudia, additional, Schlembach, Dietmar, additional, Schleußner, Ekkehard, additional, Schütz, Florian, additional, Seifert-Klauss, Vanadin, additional, Stubert, Johannes, additional, and Surbek, Daniel, additional

Published
2023
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31. Prevention and Therapy of Preterm Birth. Guideline of the DGGG, OEGGG and SGGG (S2k-Level, AWMF Registry Number 015/025, September 2022) – Part 1 with Recommendations on the Epidemiology, Etiology, Prediction, Primary and Secondary Prevention of Preterm Birth

Author

Berger, Richard, additional, Abele, Harald, additional, Bahlmann, Franz, additional, Doubek, Klaus, additional, Felderhoff-Müser, Ursula, additional, Fluhr, Herbert, additional, Garnier, Yves, additional, Grylka-Baeschlin, Susanne, additional, Hayward, Aurelia, additional, Helmer, Hanns, additional, Herting, Egbert, additional, Hoopmann, Markus, additional, Hösli, Irene, additional, Hoyme, Udo, additional, Kunze, Mirjam, additional, Kuon, Ruben-H., additional, Kyvernitakis, Ioannis, additional, Lütje, Wolf, additional, Mader, Silke, additional, Maul, Holger, additional, Mendling, Werner, additional, Mitschdörfer, Barbara, additional, Nothacker, Monika, additional, Olbertz, Dirk, additional, Ramsell, Andrea, additional, Rath, Werner, additional, Roll, Claudia, additional, Schlembach, Dietmar, additional, Schleußner, Ekkehard, additional, Schütz, Florian, additional, Seifert-Klauss, Vanadin, additional, Stubert, Johannes, additional, and Surbek, Daniel, additional

Published
2023
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32. Prevention and Therapy of Preterm Birth. Guideline of the DGGG, OEGGG and SGGG (S2k Level, AWMF Registry Number 015/025, September 2022) – Part 2 with Recommendations on the Tertiary Prevention of Preterm Birth and on the Management of Preterm Premature Rupture of Membranes

Author

Berger, Richard, additional, Abele, Harald, additional, Bahlmann, Franz, additional, Doubek, Klaus, additional, Felderhoff-Müser, Ursula, additional, Fluhr, Herbert, additional, Garnier, Yves, additional, Grylka-Baeschlin, Susanne, additional, Hayward, Aurelia, additional, Helmer, Hanns, additional, Herting, Egbert, additional, Hoopmann, Markus, additional, Hösli, Irene, additional, Hoyme, Udo, additional, Kunze, Mirjam, additional, Kuon, Ruben-H., additional, Kyvernitakis, Ioannis, additional, Lütje, Wolf, additional, Mader, Silke, additional, Maul, Holger, additional, Mendling, Werner, additional, Mitschdörfer, Barbara, additional, Nothacker, Monika, additional, Olbertz, Dirk, additional, Ramsell, Andrea, additional, Rath, Werner, additional, Roll, Claudia, additional, Schlembach, Dietmar, additional, Schleußner, Ekkehard, additional, Schütz, Florian, additional, Seifert-Klauss, Vanadin, additional, Stubert, Johannes, additional, and Surbek, Daniel, additional

Published
2023
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34. Prevention and therapy of preterm birth : guideline of the DGGG, OEGGG and SGGG (S2k level, AWMF registry number 015/025, September 2022) - part 2 with recommendations on the tertiary prevention of preterm birth and on the management of preterm premature rupture of membranes

Author

Berger, Richard, Abele, Harald, Bahlmann, Franz, Doubek, Klaus, Felderhoff-Müser, Ursula, Fluhr, Herbert, Garnier, Yves, Grylka, Susanne, Hayward, Aurelia, Helmer, Hanns, Herting, Egbert, Hoopmann, Markus, Hösli, Irene, Hoyme, Udo, Kunze, Mirjam, Kuon, Ruben-H., Kyvernitakis, Ioannis, Lütje, Wolf, Mader, Silke, Maul, Holger, Mendling, Werner, Mitschdörfer, Barbara, Nothacker, Monika, Olbertz, Dirk, Ramsell, Andrea, Rath, Werner, Roll, Claudia, Schlembach, Dietmar, Schleußner, Ekkehard, Schütz, Florian, Seifert-Klauss, Vanadin, Stubert, Johannes, Surbek, Daniel, Berger, Richard, Abele, Harald, Bahlmann, Franz, Doubek, Klaus, Felderhoff-Müser, Ursula, Fluhr, Herbert, Garnier, Yves, Grylka, Susanne, Hayward, Aurelia, Helmer, Hanns, Herting, Egbert, Hoopmann, Markus, Hösli, Irene, Hoyme, Udo, Kunze, Mirjam, Kuon, Ruben-H., Kyvernitakis, Ioannis, Lütje, Wolf, Mader, Silke, Maul, Holger, Mendling, Werner, Mitschdörfer, Barbara, Nothacker, Monika, Olbertz, Dirk, Ramsell, Andrea, Rath, Werner, Roll, Claudia, Schlembach, Dietmar, Schleußner, Ekkehard, Schütz, Florian, Seifert-Klauss, Vanadin, Stubert, Johannes, and Surbek, Daniel

Abstract

Artikel in mehreren Sprachen: Englisch und Deutsch, Aim: The revision of this guideline was coordinated by the German Society for Gynecology and Obstetrics (DGGG), the Austrian Society for Gynecology and Obstetrics (OEGGG) and the Swiss Society for Gynecology and Obstetrics (SGGG). The aim of the guideline is to improve the prediction, prevention and management of preterm birth based on evidence from the current literature, the experience of members of the guidelines commission, and the viewpoint of self-help organizations. Methods: The members of the contributing professional societies and organizations developed recommendations and statements based on international literature. The recommendations and statements were presented and adopted using a formal process (structured consensus conferences with neutral moderation, written Delphi vote). Recommendations Part 2 of this short version of the guideline presents statements and recommendations on the tertiary prevention of preterm birth and the management of preterm premature rupture of membranes. Ziel: Überarbeitete Leitlinie der Deutschen Gesellschaft für Gynäkologie und Geburtshilfe (DGGG), der Österreichischen Gesellschaft für Gynäkologie und Geburtshilfe (OEGGG) und der Schweizerischen Gesellschaft für Gynäkologie und Geburtshilfe (SGGG). Ziel der Leitlinie ist es, die Prädiktion, die Prävention und das Management der Frühgeburt anhand der aktuellen Literatur, der Erfahrung der Mitglieder der Leitlinienkommission einschließlich der Sicht der Selbsthilfe evidenzbasiert zu verbessern. Methoden: Anhand der internationalen Literatur entwickelten die Mitglieder der beteiligten Fachgesellschaften und Organisationen zahlreiche Empfehlungen und Statements. Diese wurden in einem formalen Prozess (strukturierte Konsensuskonferenzen mit neutraler Moderation, schriftliche Delphi-Abstimmung) verabschiedet. Empfehlungen: Der Teil 2 dieser Kurzversion der Leitlinie zeigt Statements und Empfehlungen zur tertiären Prävention der Frühgeburt sowie zum Management des frühen vorzeitig

Published
2023

35. Prevention and therapy of preterm birth : guideline of the DGGG, OEGGG and SGGG (S2k-level, AWMF registry number 015/025, September 2022) - part 1 with recommendations on the epidemiology, etiology, prediction, primary and secondary prevention of preterm birth

Author

Berger, Richard, Abele, Harald, Bahlmann, Franz, Doubek, Klaus, Felderhoff-Müser, Ursula, Fluhr, Herbert, Garnier, Yves, Grylka, Susanne, Hayward, Aurelia, Helmer, Hanns, Herting, Egbert, Hoopmann, Markus, Hösli, Irene, Hoyme, Udo, Kunze, Mirjam, Kuon, Ruben-H., Kyvernitakis, Ioannis, Lütje, Wolf, Mader, Silke, Maul, Holger, Mendling, Werner, Mitschdörfer, Barbara, Nothacker, Monika, Olbertz, Dirk, Ramsell, Andrea, Rath, Werner, Roll, Claudia, Schlembach, Dietmar, Schleußner, Ekkehard, Schütz, Florian, Seifert-Klauss, Vanadin, Stubert, Johannes, Surbek, Daniel, Berger, Richard, Abele, Harald, Bahlmann, Franz, Doubek, Klaus, Felderhoff-Müser, Ursula, Fluhr, Herbert, Garnier, Yves, Grylka, Susanne, Hayward, Aurelia, Helmer, Hanns, Herting, Egbert, Hoopmann, Markus, Hösli, Irene, Hoyme, Udo, Kunze, Mirjam, Kuon, Ruben-H., Kyvernitakis, Ioannis, Lütje, Wolf, Mader, Silke, Maul, Holger, Mendling, Werner, Mitschdörfer, Barbara, Nothacker, Monika, Olbertz, Dirk, Ramsell, Andrea, Rath, Werner, Roll, Claudia, Schlembach, Dietmar, Schleußner, Ekkehard, Schütz, Florian, Seifert-Klauss, Vanadin, Stubert, Johannes, and Surbek, Daniel

Abstract

Artikel in mehreren Sprachen: Deutsch und Englisch, Aim: This revised guideline was coordinated by the German Society for Gynecology and Obstetrics (DGGG), the Austrian Society for Gynecology and Obstetrics (OEGGG) and the Swiss Society for Gynecology and Obstetrics (SGGG). It aims to improve the prediction, prevention, and management of preterm birth, based on evidence from the current literature, the experience of members of the guidelines commission, and the viewpoint of self-help organizations. Methods: The members of the contributing professional societies and organizations developed recommendations and statements based on international literature. The recommendations and statements were presented and adopted using a formal process (structured consensus conferences with neutral moderation, written Delphi vote). Recommendations: Part 1 of this short version of the guideline presents statements and recommendations on the epidemiology, etiology, prediction, and primary and secondary prevention of preterm birth. Ziel: Überarbeitete Leitlinie der Deutschen Gesellschaft für Gynäkologie und Geburtshilfe (DGGG), der Österreichischen Gesellschaft für Gynäkologie und Geburtshilfe (OEGGG) und der Schweizerischen Gesellschaft für Gynäkologie und Geburtshilfe (SGGG). Ziel der Leitlinie ist es, die Prädiktion, die Prävention und das Management der Frühgeburt anhand der aktuellen Literatur, der Erfahrung der Mitglieder der Leitlinienkommission einschließlich der Sicht der Selbsthilfe evidenzbasiert zu verbessern. Methoden: Anhand der internationalen Literatur entwickelten die Mitglieder der beteiligten Fachgesellschaften und Organisationen zahlreiche Empfehlungen und Statements. Diese wurden in einem formalen Prozess (strukturierte Konsensuskonferenzen mit neutraler Moderation, schriftliche Delphi-Abstimmung) verabschiedet. Empfehlungen: Der Teil 1 dieser Kurzversion der Leitlinie zeigt Statements und Empfehlungen zur Epidemiologie, Ätiologie, der Prädiktion sowie der primären und sekundären Prävention der Frühgeburt.

Published
2023

36. Sepsis related mortality of extremely low gestational age newborns after the introduction of colonization screening for multi-drug resistant organisms

Author

Härtel, Christoph, Faust, Kirstin, Fortmann, Ingmar, Humberg, Alexander, Pagel, Julia, Haug, Clara, Kühl, Reinhard, Bohnhorst, Bettina, Pirr, Sabine, Viemann, Dorothee, Simon, Arne, Zemlin, Michael, Poralla, Silvia, Müller, Andreas, Köstlin-Gille, Natascha, Gille, Christian, Heckmann, Matthias, Rupp, Jan, Herting, Egbert, and Göpel, Wolfgang

Published
2020
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37. Erythrocyte transfusions are associated with retinopathy of prematurity in extremely low gestational age newborns.

Author

Glaser, Kirsten, Härtel, Christoph, Dammann, Olaf, Herting, Egbert, Andres, Oliver, Speer, Christian P., Göpel, Wolfgang, and Stahl, Andreas

Subjects
RETROLENTAL fibroplasia, RED blood cell transfusion, NEWBORN infants, NEONATAL intensive care units, GESTATIONAL age, BLOOD transfusion reaction
Abstract

Aim: Retinopathy of prematurity (ROP) is a major morbidity in preterm infants causing visual impairment including blindness. Prevention and timely treatment are critical. We investigated the potential role of red blood cell (RBC) transfusions as risk factor for ROP development. Methods: Retrospective cohort study of data from 68 tertiary level neonatal intensive care units in Germany. Preterm infants born at 22 + 0 to 28 + 6 weeks of gestation between January 2009 and December 2021 were enrolled. Results: We included n = 12 565 infants. Prevalence of any ROP was 49.2% with most infants being diagnosed with stage 1 (21.5%) and 2 disease (17.2%). ROP stage 3 was present in 10.2%, stage 4 in 0.3%, and ROP requiring treatment in 6.6%. Infants with ROP had significantly more frequently a history of RBC transfusions. Adjusting for confounders, RBC transfusions were associated with increased odds of ROP (OR 1.4, p < 0.001), ROP progression (OR 2.1, p < 0.01) and ROP requiring treatment (OR 3.6, p < 0.001). Restrictive transfusion approaches correlated with decreased (OR 0.7, p < 0.001), liberal regimes with increased odds (OR 1.2, p = 0.001). Conclusion: The present study confirmed an association of RBC transfusions and ROP. Our findings emphasise the need for anaemia prevention and critical re‐evaluation of transfusion practices in preterm infants. [ABSTRACT FROM AUTHOR]

Published
2023
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40. Chronic obstructive pulmonary disease of prematurity (COPP) – Anwendung eines polygenen Risikoscores für COPD und Lungenfunktion bei ehemaligen VLBW-Frühgeborenen im Alter von fünf Jahren

Author

Nissen, Gyde, additional, König, Inke, additional, Rausch, Tanja K., additional, Franke, Andre, additional, Brinkmann, Folke, additional, Kopp, Matthias V., additional, Weckmann, Markus, additional, Herting, Egbert, additional, and Göpel, Wolfgang, additional

Published
2023
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42. Lung Function of Preterm Children Parsed by a Polygenic Risk Score for Adult COPD

Author

Nissen, Gyde, primary, Hinsenbrock, Svenja, additional, Rausch, Tanja K., additional, Stichtenoth, Guido, additional, Ricklefs, Isabell, additional, Weckmann, Markus, additional, Franke, Andre, additional, Herting, Egbert, additional, König, Inke R., additional, Kopp, Matthias V., additional, Rabe, Klaus F., additional, and Göpel, Wolfgang, additional

Published
2023
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44. Does Breastmilk Influence the Development of Bronchopulmonary Dysplasia?

Author

Bendiks, Meike, Berghäuser, Martin A., Böckenholt, Kai, Bohnhorst, Bettina, Böttger, Ralf, Brune, Thomas, Dawczynski, Kristin, Dördelmann, Michael, Ehlers, Silke, Eichhorn, Joachim G., Felderhoff-Müser, Ursula, Franz, Axel, Gebauer, Corinna, Gerleve, Hubert, Göpel, Wolfgang, Gortner, Ludwig, Haase, Roland, Heitmann, Friedhelm, Hentschel, Roland, Hepping, Nico, Hillebrand, Georg, Höhn, Thomas, Hörnig-Franz, Isabelle, Hubert, Mechthild, Jenke, Andreas, Jensen, Rainer, Kannt, Olaf, Körner, Hans T., Kribs, Angela, Küster, Helmut, Linnemann, Knud, Möller, Jens, Müller, Andreas, Müller, Dirk, Olbertz, Dirk M., Orlikowsky, Thorsten, Reese, Jochen, Roll, Claudia, Rossi, Rainer, Rüdiger, Mario, Schaible, Thomas, Schiffmann, Jan-Holger, Schmidkte, Susanne, Seeliger, Stephan, Segerer, Hugo, Siegel, Jens, Teig, Norbert, Urlichs, Florian, Wense, Axel von der, Vochem, Matthias, Weller, Ursula, Wieg, Christian, Wintgens, Jürgen, Spiegler, Juliane, Preuß, Michael, and Herting, Egbert

Published
2016
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45. Indomethacin Prophylaxis Is Associated with Reduced Risk of Intraventricular Hemorrhage in Extremely Preterm Infants Born in the Context of Amniotic Infection Syndrome

Author

Hanke, Kathrin, Fortmann, Ingmar, Humberg, Alexander, Faust, Kirstin, Kribs, Angela, Prager, Sebastian, Felderhoff-Müser, Ursula, Krüger, Marcus, Heckmann, Matthias, Jäger, Anja, Andres, Oliver, Spiegler, Juliane, Härtel, Christoph, Herting, Egbert, and Göpel, Wolfgang

Subjects
Medizin
Abstract

in press

Published
2023

46. [Untitled]

Author

Berger, Richard, Abele, Harald, Bahlmann, Franz, Doubek, Klaus, Felderhoff-Müser, Ursula, Fluhr, Herbert, Garnier, Yves, Grylka-Baeschlin, Susanne, Hayward, Aurelia, Helmer, Hanns, Herting, Egbert, Hoopmann, Markus, Hösli, Irene, Hoyme, Udo, Kunze, Mirjam, Kuon, Ruben-H, Kyvernitakis, Ioannis, Lütje, Wolf, Mader, Silke, Maul, Holger, Mendling, Werner, Mitschdörfer, Barbara, Nothacker, Monika, Olbertz, Dirk, Ramsell, Andrea, Rath, Werner, Roll, Claudia, Schlembach, Dietmar, Schleußner, Ekkehard, Schütz, Florian, Seifert-Klauss, Vanadin, Stubert, Johannes, and Surbek, Daniel

Subjects
610 Medicine & health
Abstract

Aim The revision of this guideline was coordinated by the German Society for Gynecology and Obstetrics (DGGG), the Austrian Society for Gynecology and Obstetrics (OEGGG) and the Swiss Society for Gynecology and Obstetrics (SGGG). The aim of the guideline is to improve the prediction, prevention and management of preterm birth based on evidence from the current literature, the experience of members of the guidelines commission, and the viewpoint of self-help organizations. Methods The members of the contributing professional societies and organizations developed recommendations and statements based on international literature. The recommendations and statements were presented and adopted using a formal process (structured consensus conferences with neutral moderation, written Delphi vote). Recommendations Part 2 of this short version of the guideline presents statements and recommendations on the tertiary prevention of preterm birth and the management of preterm premature rupture of membranes.

Published
2023
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48. Sleep problems in infancy and early school age in very preterm infants

Author

Neitmann, Johanna, primary, Hanke, Kathrin, additional, Humberg, Alexander, additional, Siller, Bastian, additional, Spiegler, Juliane, additional, Juhnke, Karla, additional, Gilmore, Jessica, additional, Odendahl, Rainer, additional, Herting, Egbert, additional, Göpel, Wolfgang, additional, Härtel, Christoph, additional, and Fortmann, Ingmar, additional

Published
2022
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49. Multi‐centre randomised trial of invasive and less invasive surfactant delivery methods showed similar spirometry results at 5–9 years of age

Author

Göpel, Wolfgang, primary, Kribs, Angela, additional, Roll, Claudia, additional, Wieg, Christian, additional, Teig, Norbert, additional, Hoehn, Thomas, additional, Welzing, Lars, additional, Vochem, Matthias, additional, Hoppenz, Marc, additional, Bührer, Christoph, additional, Mehler, Katrin, additional, Hubert, Mechthild, additional, Eichhorn, Joachim, additional, Schmidtke, Susanne, additional, Rausch, Tanja Katrin, additional, König, Inke Regina, additional, Härtel, Christoph, additional, Roth, Bernd, additional, and Herting, Egbert, additional

Published
2022
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50. The assessment of future RSV immunizations: How to protect all infants?

Author

Bont, Louis, primary, Weil Olivier, Catherine, additional, Herting, Egbert, additional, Esposito, Susanna, additional, Navarro Alonso, Jose Antonio, additional, Lega, Federico, additional, Mader, Silke, additional, Morioka, Ichiro, additional, Shen, Kunling, additional, Syrogiannopoulos, George A., additional, Faust, Saul N., additional, and Bozzola, Elena, additional

Published
2022
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