105 results on '"Hershkovitz Y"'
Search Results
2. An increased risk for ischemic stroke in the short-term period following COVID-19 infection
- Author
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Keinan Boker, L, primary, Libruder, C, additional, Hershkovitz, Y, additional, Ben Yaish, S, additional, Tanne, D, additional, and Binyaminy, B, additional
- Published
- 2023
- Full Text
- View/download PDF
3. Should cholangiography be part of the management of every patient with percutaneous cholecystostomy?
- Author
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Ben Yehuda, A., primary, Markov, E., additional, Jeroukhimov, I., additional, Lavy, R., additional, and Hershkovitz, Y., additional
- Published
- 2022
- Full Text
- View/download PDF
4. Total Pancreatectomy for Head of the Pancreas Tumor - Surprising Findings
- Author
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Shapira, O.Y., primary, Shapira, Z., additional, Ben-Yehuda, A., additional, Hershkovitz, Y., additional, Zmora, O., additional, and Lavy, R., additional
- Published
- 2022
- Full Text
- View/download PDF
5. SARS-CoV-2 vaccination modelling for safe surgery to save lives: data from an international prospective cohort study
- Author
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COVIDSurg Collaborative, GlobalSurg Collaborative, A, M., Abdelhamid, M. H. S., Alhabdan, S., Nekoval, V., Nel, C., Nel, D., Nel, H., Nelihela, P., Nelissen, E., Nelli, T., Nelson, C., Nemeth, M., Nene, A., AlHADAD, M., Neo, E. L., Neo, E. N., Neri, C. M., Neshige, S., Nespoli, L. C., Nessa, A., Nessim, C., Neuerburg, C., Neves, F., Neves, M., Alhaddad, A., Newcomb, A., Newitt, L., Newman, J., Newman, M., Newman, S., Newton, L., Neykov, V., Nezerwa, Y., Nezi, G., Ng, B., Alhaddad, W., Ng, C. S. H., Ng, C. F., Ng, C. E., Ng, D., Ng, D. S. W., Ng, J. C. K., Ng, J. Y., Ng, J., Ng, K. K., Ng, K. C., Alhadeethi, A., Ng, M. Y., Ng, M., Ng, S., Ng We Yong, Y. J., Ng-Kamstra, J., Ngan, T. Y., Ngaserin, S., Ngeruka, M. L., Ngu, J., Alhadi, A., Ngulube, A., Nguyen, A., Nguyen, H. M. N., Nguyen, H., Nguyen, S., Ni Bhroin, O., Nia, A., Niazi, F. A. K., Niazi, M., Alhag, A., Niazi, S. U., Nichani, J., Nichita, M., Nicholas, E., Nicholson, K., Nicholus, M., Nicolaiciuc, S., Nicolas, B., Nicolás-López, T., Niculae, C., Alhaidari, A., Nidaw, M., Nielsen, M. F., Niemeier, A., Nieto Calvache, A. J., Nieto Rodriguez, J. M., Nieto-Moreno, A., Nieto-Moreno, E., Nigalye, N., Nikaj, H., Nikiteas, N., Alhaje, A., Nikolai, K., Nikolaieva, K., Nikolic, S., Nikoloudaki, Z., Nikolouzakis, T., Nikolovska, B., Nikoupour, H., Nikova, A., Nimako, B., Nimako-Mensah, J., Alhajji, Z., Nimale, S., Nimer, B., Ninan, J. E., Ninic, A., Ninkovic, M., Niño Corredor, R. A., Niquen-Jimenez, M., Nirgude, A., Niriella, S., Nisa, K., Abdeljalil, A., AlHajri, N., Nischwitz, S. P., Nishihara, N., Nishikawa, K., Niska, K., Nistor-Ciurba, C. C., Nitschke, C., Nixon, A., Niyongombwa, I., Nizami, M., Niziol, R., Alhakami, N., Njeze, N., Njim, T., Njuki, P. N., Nk, V., Nkole, T., Nkrumah, J., Nkubito, J. M. S., Nkunzimana, E., Nabugwu, I., Najiuba, H., Alhalal, H., Noah, K., Nocera, G., Noda, M., Noe, C., Noel, C., Noël, A., Nofal, S., Noguchi, H., Nogueiro, J., Noguera Roman, L., Alhamid, A., Nogués, A., Noguez Castillo, M., Noiret, B., Nolan, D., Noll, F., Nolte, P., Noltes, M., Noman, H., Nomura, T., Noone, A., Noor, A., Noor, D. F., Noor Mohamed, M. S., Noordin, S., Noori, E., Noori, F., Norawat, R., Nordberg, M., Noreen, D. Z., Noriega, D. C., Alhamid, M., Norman, L., Noro, S., Noronha, W. J., Norouzi, S., Norris, J., Norrish, A., Nortey, M., Norton, J., Norton, S., Norton, W., Alhammad, O., Notario, J., Noton, T., Notz, Q., Nouh, T., Noureen, D. S., Noureldin, Y., Novak, Z., Novello, S., Novembre, D., Novi, A., Alhammali, T., Novikov, D., Novikova, A., Novoa, B., Novotny, H. F. G., Novysedlák, R., Nowak, K., Nowar, M., Nowosielski, Y., Nsaful, J., Nshuti, S., AlHarazi, A., Ntaganda, E., Ntalouka, M., Ntege, A., Ntege, J., Ntezamizero, J., Ntirenganya, F., Ntoto, M. C. O., Ntziovara, A. M., Nubair, S., Nugent, T., Alharthi, B., Nugur, A., Nuh, A., Nunes, R., Nunes, S., Nunes Coelho, M., Nunez, J., Nuñez, J., Nuñez, R., Núñez, A., Núñez, B., Abdelkabir, M., Alharthi, M., Nuñez Del Barrio, H., Núñez Lucic, J., Núñez O'Sullivan, S., Nunez-Garcia, B., Núñez-González, RÁ, Nuño-Escobar, C., Nurgozhin, T., Nuseir, A., Nwabuoku, S. E., Nwachukwu, C., Alharthi, N., Nwachukwu, I., Nwafor, I., Nwagboso, C., Nwaorgu, O., Nwashilli, N., Nwegbu, C., Nwinee, H., Nwosu, D., Nyadu, B., Nyangoh Timoh, K., Alharthi, S., Nyarko, O. O., Nyarko Agyeman, Y., Nyeko-Lacek, M., Nygaard, R. M., Nyirahabakurama, D., Nyirahabimana, J., Nyirimodoka, A., O Connor, C., O'Banion, L. A., O'Brien, S., Alhasan, H., O'Connell, E., O'Connell, R., O'Connor, B., O'Connor, D. B., O'Connor, J., O'Connor, Z., O'Donnell, R., O'Donoghue, C., O'Donoghue, G., O'Farrell, E., ALhassan, A., O'Grady, M., O'Hagan, P., O'Kelly, J., O'Mara-Gardner, K., O'Neill, A., O'Neill, C., O'Neill, R., O'Shea, M., O'Sullivan, E., Obadan, I., Alhassan, B. A. B., Obahiagbon, O., Obaid, K., Obaid, M., Obara, S., Obateru, J., Obbeng, A., Obeidat, R., Obied, H., Obrist, C., Obuekwe, O., Alhassan, B., Obure, R., Ocampo, L., Ocampos, L., Ocampos Hernandez, M., Occhionorelli, S., Ochoa Carrillo, F. J., Ochoa Gaete, K., Ochoa Villalabeitia, B., Ocsan, R. J., Od, S., Alhassoun, T., Odai, E. D., Odedra, A., Odeh, A., Odejinmi, F., Odetto, D., Odeyemi, O., Odeyemi, P. O., Odicino, F., Odigie, P. V., Odonnell, E., Alhathal, N., Oduah, S., Odunafolabi, T., Oduola, O., Odutola, O., Offiong, R., Ofori, B., Ofori, E. O., Ofosu-Barko, B. B., Ogawa, M., Ogden, E., Alhattab, M., Ogenya, R., Ogihara, T., Ogu, R., Ogunade, O., Ogundele, I., Ogundoyin, O., Ogunkeyede, S. A., Ogunlaja, O., Ogunrewo, T., Abdelkader Salama, I., Alhawatmeh, M., Ogunsua, O., Oguttu, B., Oğuz, C., Ohama, S., Ohara, R., Ohazurike, E., Oikonomou, K., Ojeda Rojas, A. M., Ojeda Thies, C., Ojeda Villasboa, D. J., Alhazmi, A., Ojewola, R. W., Ojha, B. K., Ojo, O., Okada, H., Okada, R., Okada, S., Okada, T., Okafor, B., Alhazmi, B., Okail, M. H., Okamura, K., Okamura, Y., Okere, O., Okereke, C., Okhakhu, A., Okolie, L., Okonkwo, I., Okoro, K., Okoye, E., Alhazzaa, N., Okoye, O., Okpani, A., Okpani, C., Okugbo, S., Okunade, K., Okunlola, A., Okunowo, A., Okwara, B., Olabinjo, A., Oladejo, T., Alhefdhi, A., Oladiran, A., Olagunju, N., Olajide, A., Olajide, T. O., Olaogun, J., Olaomi, O., Olaosebikan, R., Olaoye, I., Olasehinde, O., Olatoke, S. A., Alhelal, B., Olave Montaño, V. D., Olawoye, O., Olayiwola, D. O., Olaywah, D., Olaywah, N., Oldani, M., Oldbury, M., Oldrà, G., Olea Vielba, C., Olearo, E., Alhelal, F., Olieman, A., Oliva, A. R., Oliva, J. R., Oliva, R., Olive, R., Oliveira, A., Oliveira, J., Oliveira, J. C. C., Oliver, T., Alhemyari, N., Oliver García, L., Oliver Guillen, J. R., Olivos, M., Ollat, D., Oller, I., Olliff, S., Ollivere, B., Olmedo Bareiro, R. I., Olmi, S., Olori, S., Alherabi, A., Olowogbayi, T., Olson, K. A., Olubayo, O. O., Olugbami, A., Oluka, D. D., Olulana, D., Olusanya, A., Olute, A., Oluwafemi, F., Olvera-Flores, O. E., Alhindi, R., Omar, K., Omar, M., Omar, M. W., Omar, N. G., Omar, O. M., Omar, S., Omar, W., Omar Abunaaja, H., Omara, U., Abdelkareem, M., Alhogbani, M., Omari, R. Y., Ombashi, S., Omeje, U. K., Omer, M. E. A., Ömer, ÖA., Ömeroğlu, S., Omigbodun, A., Omiragi, P., Omisanjo, O., Omotosho, P., Alhossaini, R., Omran, J., Onakoya, P., Onate, J., Oñate, M., Önder, A. B., Öney, M. D., Ong, B. S., Ong, C. F., Ong, D., Ong, J. H., Alhouni, T., Ong, L., Ong, M. T. Y., Ong Vaño, A. M., Oni, O., Oni, S., Onjefu, S., Ono, M., Onochie, E., Onorati, I., Onubogu, I. K., Alhouri, A., Onur, I. U., Onwuagha, I., Onyeagwara, N., Onyeji, J., Onyemaechi, N., Onzi, T. R., Oo, A., Ooi, C., Ooi, R., Ooi, S. Z. Y., ALhumaida, A., Oosterlinck, W., Oosterling, S., Oosthuizen, B., Opandoh, I. N. M., Opano, R., Opincans, J., Opoku Amankwaa, W., Oppah, I., Oppong, P. P., Oputa, V., Alhunaidi, O., Orădan, A., Oranu, E., Orazulike, N., Ordemar, J., Ordoñez, S., Organ, N., Organjee, A., Orgoi, S., Orhan, N., Orhan Sungur, M., Alhussaini, A., Orji, I. J., Orji, M., Ormeño, M., Ornaghi, S., Oropeza, M., Orozco-Chamorro, C. M., Orozco-Perez, J., Orsoo, S., Orta Díaz, M. D., Ortega, N., Alhussein, A., Ortega, S., Ortega Oria de Rueda, M., Ortega Vázquez, I., Ortega-Jiménez, J. A., Ortiz, E. V., Ortiz, L., Ortiz, M. R., Ortiz De La Cruz, F., Ortiz de Solórzano Aurusa, F. J., Ortiz López, D., Alhuthayl, M., Ortiz Silva, C., Ortiz Simón, A., Oruç, M., Oryadi Zanjani, L., Osabutey, A., Osagie, O., Osaki, S., Osborn, T., Osborne, L., Oscarsson, A., Ali, A. A. A., Osea, L., Oseghale, E., Osei-Bonsu, P., Osei-Poku, D., Osei-Tutu, E., Osemwegie, O., Osho, P., Osinaike, B., Osl, A., Osman, A., Abdelkarem, M. M., Ali, A. D., Osman, E., Osman, H., Osman, I., Osman, K., Osman, L., Osman, M., Osman, M. F., Osorio, D., Osorio, W. A., Ali, A. A., Ossman, M. A., Osterberg, E. C., Osterhoff, G., Ostrovsky, I. A., Osuna, L., Osuna-Rubio, J., Osuoji, R., Otaif, W., Otayfah, S., Otchwemah, R., Ali, A., Oteem, A., Oter, V., Othieno Misanga, H., Othiyil Vayoth, S., Othman, A., Othman, A. F., Othman, E., Othman, M., Othman, S., Otieno, J., Otify, M., Otiniano Alvarado, C. E., Otokwala, D. J., Ots, R., Otsuka, Y., Ott, J., Otte, H., Ottl, S., Ou, C. X. Y., Ali, A. M., Ouchi, T., Oudrhiri, M. Y., Ouf, A., Ould Si Amar, A., Ourieff, J., Ourô, S., Ousouss, S., Outani, O., Owaimer, R., Owais, Q., Owens, D., Owens, P., Ower, C., Owiedat, M., Owusu Adae, J., Oyama, T., Oyediji, F., Oyelakin, O., Oyeleye, O., Oyelowo, N., Oyende, O., Oyewole, O., Oyewusi, E., Oyinloye, O., Ozair, A., Özant, A., Ozben, V., Özcan, A., Özçay, N., OZcelık, M. F., Ozdemir, E., Ozdemir, K., Özdoğan, K., Özeller, E., Ozgediz, D., Özgen, U., Ozgur, I., Ozkan, O. F., Ozkent, M. S., Ozmen, M. M., Ozone, C., Özpak, S. S., Oztan, M. O., Ozua, J., P B, H., P L, T., Paal, P., Pabari, A., Pablo, C., Pacheco Sánchez, D., Pachl, M., Pacilio, C. A., Pacilli, M., Padilla-Valverde, D., Padmore, G., Páez, W., Pagano, G., Pagano, L., Page, R., Pagès, N., Abdelkarim, M., Ali, D., Pahalawatta, U., Paiano, L., Paiella, S., Paine, W., Pais, J., Paitici, S., Paiva, J., Paiva Vera, D. A., Paiva-Santos, F., Pajan, H., Pajić, S., Pal, U. S., Palacios, C., Palacios, J., Palapalle, N., Palayan, K., Palazon Bellver, P., Palines, A., Palla, E., Palm, H., Ali, F., Palma, M., Palma Caucig, N., Palmeri, M., Palmerini, E., Palmieri, G., Palmisano, S., Palomares Casasús, S., Palomino, L., Palomino Escalante, F., Palta Uribe, D. A., Ali, G., Paltoglou, N., Palumbo, A., Palumbo, M., Paluso Montero, A. V., Pamias, J., Panagiotidou, S., Panagiotou, P., Panayiotou, Y., Panayotova, G., Panchakshariah, S., Ali, I., Panciani, P. P., Panda, A., Panda, R., Pandey, A., Pandey, H., Pandey, S., Pañeda, L., Panesar, D., Pang, J. H., Panigrahi, S., Panis, C., Panjwani, T., Pannullo, M., Panov, I., Pansani, A., Pant, R., Panteli, C., Pantelidou, M., Pantoja Pachajoa, D. A., Pantos, P., Ali, I. A., Panuganti, V., Panyko, A., Paolini, B., Papa, A., Papaconstantinou, I., Papadia, A., Papadopoulos, V., Papadopoulou, T., Papagni, V., Papalampros, A., Papalexandris, S., Papalia, R., Papandrea, M., Papanikolaou, V., Papas, T., Papatheodorou, P., Papavasiliou, K., Papendick, N., Papidze, K., Pappas, S., Ali, M., Parab, D. M., Parab, S., Parada Rodriguez, A. M., Parakonthun, T., Paramasivan, A., Páramo Zunzunegui, J., Paranjape, C., Paraskevas, K. I., Paraskevopoulos, K., Pardes, R., Pardilho, A., Pardiwala, D., Paredes, I., Paredes, S., Paredes Caturiny, A., Pareed, D. D., Pareek, P., Pareja Ciuro, F., Parekh, J. N., Parello, A., Parente, A., Parfitt, C., Pargal, D. P., Parija, S., Paris, M., Park, A., Park, C., Park, F., Park, J. J., Park, J., Park, M., Park, P., Park, S. S. W., Parker, D., Parker, K. L., Parker, M. Y., Parker, R., Parkin, B., Parkin, C., Parkin, E., Parlanti, D., Parmar, C., Parodi, M., Parra Abaunza, K., Parra Baños, P. A., Parray, F., Parreira, P., Parri, P., Parrish, A., Parry, J., Parry, L., Parry-Smith, W., Parshad, R., Parsons, S., Parsons, T., Parulekar, R., Parveen, S., Parwaiz, H., Pascale, M. M., Pascarella, G., Ali, M. U., Pascua-Gómez, L. A., Pascual, Á, Pascual Arellano, M. P., Pascual Escudero, V., Pascual Miguelañez, I., Pascual Samaniego, M., Pascual-Cambero, P., Pasini, M., Pasquini, E., Passadore, M., Ali, N., Pastor, O., Pastor, T., Pastor Nieto, M. B., Pastor Zapata, A., Pata, F., Patabendige, M., Patachia, R., Patel, A., Patel, A. M. E., Ali, R., Patel, B., Patel, J., Patel, K., Patel, L., Patel, M., Patel, N., Patel, P., Ali, S., Patel, R., Patel, S., Patelis, N., Patell, M., Patena Forte, J., Paterson, A., Paterson, H., Pathak, M., Pathak, P., Pathak, S., Pathan, S., Pathmanaban, O., Pathmanathan, K., Patil, M., Patil, N., Patil, R., Patini, R., Patino-Jaramillo, N. G., Patkar, A., Patkar, P., Patkar, S., Patoulias, I., Patra, S., Patrizi, A., Patrone, R., Patzer, K., Abdelkhalek, M., Paucar Urbina, A. D. P., Paul, C., Paul, E., Paul, M., Paul, R., Paul, S., Paulino, H., Paulino, J., Paulo, M., Paulsen, L., Ali, W., Paunero Vazquez, P., Paunovic, A., Paunovic, I., Pavic Palac, P., Pavithran, A., Pavlov, M., Pavlov, P., Pavlovic, I., Pāvulāns, J., Pawar, A., Ali, Y., Pawar, N., Pawar, P., Pawar, S., Payá-Llorente, C., Payet, E., Pazmino-Canizares, J., Pb, B. K. P. B., Pcolkins, A., Pearce, A., Pearson, N., Ali Akbari, A., Pecchini, F., Peckham-Cooper, A., Pecoraro, A., Pecoraro, F., Pednekar, A., Pedraza Alonso, N. F., Pedraza Salazar, I. I., Pedrazzani, C., Pedreira Duprat Neto, J., Pedrero Escalas, M. F., Ali Al-Radhi, A. M., Pedrini Cruz, R., Pedro, J., Pedrosa, L., Pedroso Alvarenga, B. D., Pedroso de Lima, R., Pędziwiatr, M., Peerally, B. N., Peeriyah, S., Peev, I., Pehar, H., Ali Karar, A. A., Peiper, C., Peirce, C., Peiris, B., Pejkova, S., Pejovic, I., Pelegrina-Lopez, M. L., Pelet, S., Pellacani, A., Pellegrini, A., Pelletier, G., Ali Mohamed, M., Pelli, M., Pellicano', G. A., Pellini, R., Pellino, G., Pelloni, M., Peltrini, R., Pempe, C., Peña Balboa, L. G., Peña Gómez Portugal, E., Peña Ros, E., Ali Saad Salama, S., Peñarrocha, J., Pendyala, K. S., Penezić, L., Peng, E., Pengermä, P., Pennington, R., Penserga, E., Pepe, G., Peralta Ferreira, M., Peravali, R., Ali Shaikh, S., Percy, D., Perea Del Pozo, E., Perea Serna, A. C., Pereca, J., Pereda, A., Pereda, M., Pereira, A., Pereira, C., Pereira, F. C., Pereira, M., Aliaga-Sanchez, A., Pereira, R., Pereira-Neves, A., PereiraNuñez, D., Perepelitsa, O., Perera, E., Perera Sarri, R., Perets, M., Peretti, M., Perez, I., Perez, Y., Abdellah, F., Alias, A., Pérez, C., Pérez, K. D., Pérez Cajti, J. D., Perez Cerdeira, M., Pérez Costoya, C., Pérez de León Vázquez, M. P., Pérez Febles, M., Perez Fernandez, M. A., Perez Ferrer, A., Perez Gonzalez, M., Aliosin, O., Pérez González, M., Perez Granados, C., Pérez López, F., Pérez Meave, J. A., Pérez Palao, S., Perez Rivera, C. J., Pérez Romero, N., Pérez Rubio, Á, Pérez Santiago, L., Pérez Uribe, R. A., Alis, H., Perez Vidal, R., Perez Villena, J., Pérez-Bertólez, S., Perez-Chrzanowska, H., Pérez-Navarro, J. V., Pérez-Saborido, B., Pérez-Sánchez, L. E., Pérez-Tierra Ruiz, J. V., Pergolini, I., Perić, I., Aliwa, M., Perini, M., Perinotti, R., Peris, N., Perišić, G., Perivoliotis, K., Perkins, R., Peros, G., Perra, T., Perreas, K., Perricos, A., Aliyeva, G., Perrone, A. M., Perrone, F., Perrone, G., Perrot, O., Persad, A., Persiani, R., Pertile, D., Perumal Kanniappan, A., Pervaiz, A., Pesántez Peralta, M. A., Aliyeva, Z., Pesce, A. L., Pesce, V., Pesenti, G., Peshattiwar, V., Pesquera, L., Pessaux, P., Pesta, M., Peswani, A., Petagna, L., Peteja, M., Aliyu, M. S., Peters, L., Peters, P., Petersson, J., Petousis, S., Petrakis, N., Petrauskas, D., Petrenko, K., Petrillo, M., Petropoulos, K., Petrovic, B., Alizadeh, N., Petrovic, M., Petrusan, A., Petruț, B., Petruzzi, G., Petzold, A., Peyroteo, I., Pezeshki Modarres, M., Pezzuto, A. P., Pfingst Rojas, C., Pfister, K., Aljabali, A., Phadnis, A., Pham, H., Pham, T., Phan, D., Phang, I., Phanse, S. S., Philip, A., Philip, K., Philip, M., Phillip, A., Aljabri, M., Phillips, D., Phillips, E., Phillips, J., Phillips, R., Phung, D., Piachas, A., Picardo, A. L., Picariello, M., Picazo Pineda, E., A Azab, M., Abdelmajeed, A., Aljabri, N., Picazo Pineda, F., Picchetto, A., Picciariello, A., Piccioni, S. A., Piccoli, M., Pichardo, M., Pichi, B., Pichler de Oliveira, C., Picon Molina, H., Picón Rodríguez, R., Aljafari, A., Picone, E., Picotti, V., Pie, S., Pieniowski, E., Pieretti, A., Pierre, T., Piessen, G., Pieteris, L., Pietrobon, G., Pigeolet, M., Pignataro, L., Pignatti, M., Pigott, L., Pijanovic, N., Pilarski, A., Pillai, S., Pillay, N., Pillerstorff, R., Piloni, M., Aljaiuossi, A., Pilu, G., Pina-Vaz, T., Pinar, U., Pincheira, C., Pineau, A., Pinfold, E., Pinheiro, G., Pinho, S., Pinilla Morales, R. E., Pinjala, M., Aljanabi, M., Pino Diaz, V., Pinotti, E., Pinsak, A., Pintado Mejia, J. F., Pinto, A., Pinto, F., Pinto, J., Pinto, P., Pinto, V., Pinto Angulo, V., Aljanadi, F., Pintor-Tortolero, J., Pipara, A., Pipitone Federico, N. S., Pirakhmedov, M., Piras, A., Piratheep, K., Piredda, F., Pires Ferreira, E., Pirina, A., Pirmorad, S., Aljanfi, A., Pirola, F., Pirola, G. M., Piros, L., Pirozzi, N., Pirozzolo, G., Pirrello, R., Pisani, D., Pisano, M., Pisanu, A., Pisanu, F., Aljasem, R., Pisarevi, G., Pisecky, L., Piserchia, V. A., Pişkin, E., Pitcher, M., Pitkänen, J., Pittam, B., Pius Ogolekwu, I., Plachouri, K. M., Plaha, P., Aljassir, F., Planelles Gómez, J., Plante, C., Plante, M., Plarre, P., Plata, M., Plata-Bello, J., Platoff, R., Plaza, G., Plaza Valiente, C., Plontke, S., Aljebur, A., Ploski, J., Plua, K., Pobelenko, A., Poblete Carrizo, J., Pocard, M., Poch, A., Pockney, P., Pocol, M. C., Podda, M., Podevin, G., Abdelmalik, A., Aljewaied, A., Poggi, C., Poggioli, G., Poh, W. S., Poiasina, E., Poidinger, B., Poier, N., Pokharkar, H., Poku, M., Pol-Fachin, L., Pola Bandres, G., Aljiffry, M., Polaino, V., Polanco Pujol, L., Polanía Sandoval, C. 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T., Moreno Sierra, J., Moreno Suarez, M., Moreno Y Suárez, T., Moreno-Gutierrez, A., Moret, C., Moretto, G., Moretto, S., Morezzi, D., Alemán, M., Morgan, C., Morgan, E., Morgan, K., Morgan, R., Morgan, S., Morhason-Bello, J., Mori, K., Moriarty, C., Morić, T., Morichau-Beauchant, T., Alemanno, G., Moriche Carretero, M., Moris, D., Morita, T., Moriyama, M., Morla, A. A., Morley, H. L., Morna, M. T., Moro-Valdezate, D., Morochovič, R., Morote, M., Alemu, B., Morović, D., Morris, B., Morris, D., Morris, R., Morrison, J., Morrison-Jones, V., Morsy, A., Morsy, M. S., Mortada, H., Alemu, M., Mortazavi, S. M. J., Mortiers, X., Mortimer, B., Mortini, P., Morton, A., Mosabha, M., Moslemi, M. K., Mosley, F., Mosneaga, R., Mosorin, M. A., Abdelgadir, A., Alen Villamayor, V., Mosos, M., Mosquera Paz, M. S., Moss, J. L., Mossaad, M., Mosshammer, V., Mostafa, A. M. H. A. M., Mostafa, B., Mostafa, M., Mostafa, M. E., Mosteiro-Cadaval, A., Alesmail, A., Mota, C., Motallebzadeh, R., Motas, N., Motasaddi Zarandy, M., Motoyasu, A., Motter, D., Motwani, K., Moug, S., Mougahed, M., Mouhandes, A. E., Alexakis, N., Moujtahid, H., Moukoko, D., Moura, M., Mourad, M., Mouriaux, F., Mourmouris, P., Mousa, M., Moussa, A., Moustafa, E., Moutinho, L., Alexander, D., Mouw, T., Moya-Angeler, J., Moyana Muguto, V., Moyano, P., Moyo, A., Moyo, G., Moyo, N., Mozafari, M., Mozel, M., Mpagi Katassi, L., Alexander, G., Mpirimbanyi, C., Mrad, B., Mrad, M. A., Mraiyan, M., Mshelbwala, P., Msherghi, A., Mtimkulu, W., Muallem-Kalmovich, L., Mubambe, M., Alexander, P., Mubarek, K., Mubarik, A., Mubaydeen, T., Mubezi, I., Mucilli, F., Muduly, D., Muehlbacher, I., Mueller, L. K., Muftah, H., Mufth, M., Alexander, T., Muganga, D., Mughal, A., Mughal, S., Mughal, Z. U., Mugisa, D., Mugla, W., Muguerza, J. M., Muguwu, A., Muhammad, A. B., Muhammad, R., Muhammad, S., Muhammad Daneji, S., Muheilan, M., Muhemi, R., Muhmmed, K., Muhssein, H., Muhtaroğlu, A., Muhtaseb, M., Alexandrou, A., Muirhead, W., Muiru, C., Mujtaba, S. N., Mukase, S., Mukezamfura, R., Mukherjee, P., Mukherjee, S., Mukhtar, I. A., Alexe, V., Mulas Fernández, C., Mulchandani, M., Mulder, W. W., Muleta, L., Muleta, M. B., Mulita, F., Mulla, H., Mulla, O., Muller, B., Müller, A., Abdelgalel, K., Alezabi, B., Müller, K., Müller, S., Müller, T., Mulliri, A., Mulugeta, E., Mulugeta, G., Mumtaz, K., Munanzvi, K., Munarriz, M., AlFakhri, A., Munawwar, F., Muneza, S., Mungazi, S., Muniandy, M., Munini, M., Munir, M. M., Munoz, H., Munoz Abraham, A. S., Muñoz Botero, N. A., Muñoz Camarena, J. M., Alfarah, M., Muñoz de Nova, J. L., Muñoz Fernández, M. E., Muñoz Lindez, I., Muñoz Rodríguez, J. M., Muñoz Sornosa, E., Muñoz Vives, J. M., Muñoz-Bellvis, L., Munro, W., Munshi, F., Muntaka, A. M., Alfaro, H., Muntean, G. 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N., Nagra, S., Nah, S. A., Nahal, E. A., Nahm, C., Algarni, M., Nahtomi Shick, O., Naieem, M., Naik, P., Nail, D., Naimy, G., Nair, A., Nair, A. K., Nair, D., Nair, G., Algarni, S., Nair, S., Nair, V. P., Naiya, H. I. I., Najafian Motahaver, N., Najera, R., Naji, N., Naji, O., Najjad, M. K. R., Najjar, M. S., Nakagawa, S., Alghamdi, A., Nakamura, Y., Nakanishi, R., Nakano, L., Nakanwagi, C., Nakas, A., Nakata, Y., Nakazawa, H., Nakirijja, T., Namikawa, T., Namrata, D., Abdelhafez, M., Namugenyi, C., Namutosi, E., Nana, G. R., Nanayakkara, A., Nankivell, P., Naoum, N., Napolitano, L., Nappi, F., Nappo, G., Naqi, S. A., Alghamdi, A. A., Naqui, Z., Naqvi, W., Naraen, A., Naranjo, S., Narasiman, V., Narasimhan, G., Narayan, S., Narayanan, V., Narayanasamy, K., Nardi, C., Naredla, P., Narendra, D., Narroway, H., Naseem, H., Naseem, M. Y., Naseer, M., Naseer, M. A., Nashed, E., Nashidengo, P. R., Nasir, A., Alghamdi, I., Nasir, M., Naskar, U., Nasreddin, M., Nasri, M. Z., Nassali, G., Nassanga, R., Nassar, A., Nassef, M. A., Alghamdi, R., Nasser, A., Nasser, N., Nasser, S., Nassif, M., Nassif, Y., Nassimu, M., Natal Álvarez, F., Nataraja, R., Nathan, M., Nathan, S. K., ALghamdi, S., Nathani, R., Nativ, H., Naumeri, F., Naunheim, M., Naureen, S., Nausheen, S., Navaratne, L., Navarrete-Peón, A., Navarro, A., Navarro, D., Alghamdi, S., Navarro, J. C., Navarro Casado, R., Navarro Martínez, S., Navarro-Alean, J., Navarro-Barrios, A., Navarro-Sánchez, A., Nawara, H., Nawawi, A., Nayak, P., Nayen, A., Alghazal, T., Nayyer, F., Naz, F., Nazal, M., Nazar, Z., Nazia, N., Nazimi, A. J., Nazir, S., Nazir, S. F., Nazir, U., Ncogoza, I., Alghazo, A., Ndabvonga, G., Ndatewapo, F., Ndayishyigikiye, M. D., Ndegbu, C., Ndizeye, O., Ndlovu, S., Ndong, A., Neagu, A., Neal, A., Neal, N., Alghuson, L., Neal-Smith, G., Neary, P., Negash, S., Negoi, I., Negreanu, L., Negrete Ocampo, J. R., Negussie, A., Nehe, A., Neidert, N., Collaborative, Covidsurg, Collaborative Dmitri Nepogodiev, Globalsurg, F Simoes, Joana F, Li, Elizabeth, Glasbey, Jame, Picciochi, Maria, K Kamarajah, Sivesh, Gujjuri, Rohan, Bhangu, Aneel, A, Maryam, A Azab, Mohammed, A Janjua, Dratif, A Zahran, Mohammed, A Abdelaziz, Areej, Luglio, Gaetano, Surgery, Medicine and Pharmacy academic/administration, Basic (bio-) Medical Sciences, Clinical sciences, Surgical clinical sciences, Faculty of Medicine and Pharmacy, Medical Oncology, Gastroenterology, Department of Surgery, HUS Abdominal Center, Chiantera, V, Pecoraro, F, COVIDSurg Collaborative, GlobalSurg Collaborative, Paediatric Surgery, Amsterdam Gastroenterology Endocrinology Metabolism, AGEM - Endocrinology, metabolism and nutrition, Graduate School, Amsterdam Reproduction & Development (AR&D), Tytgat Institute for Liver and Intestinal Research, Institut de Recherche sur les Maladies Virales et Hépatiques (IVH), Université de Strasbourg (UNISTRA)-Institut National de la Santé et de la Recherche Médicale (INSERM), Laboratoire des sciences de l'ingénieur, de l'informatique et de l'imagerie (ICube), École Nationale du Génie de l'Eau et de l'Environnement de Strasbourg (ENGEES)-Université de Strasbourg (UNISTRA)-Institut National des Sciences Appliquées - Strasbourg (INSA Strasbourg), Institut National des Sciences Appliquées (INSA)-Institut National des Sciences Appliquées (INSA)-Institut National de Recherche en Informatique et en Automatique (Inria)-Les Hôpitaux Universitaires de Strasbourg (HUS)-Centre National de la Recherche Scientifique (CNRS)-Matériaux et Nanosciences Grand-Est (MNGE), Université de Strasbourg (UNISTRA)-Université de Haute-Alsace (UHA) Mulhouse - Colmar (Université de Haute-Alsace (UHA))-Institut National de la Santé et de la Recherche Médicale (INSERM)-Institut de Chimie du CNRS (INC)-Centre National de la Recherche Scientifique (CNRS)-Université de Strasbourg (UNISTRA)-Université de Haute-Alsace (UHA) Mulhouse - Colmar (Université de Haute-Alsace (UHA))-Institut National de la Santé et de la Recherche Médicale (INSERM)-Institut de Chimie du CNRS (INC)-Centre National de la Recherche Scientifique (CNRS)-Réseau nanophotonique et optique, Université de Strasbourg (UNISTRA)-Université de Haute-Alsace (UHA) Mulhouse - Colmar (Université de Haute-Alsace (UHA))-Centre National de la Recherche Scientifique (CNRS)-Université de Strasbourg (UNISTRA)-Centre National de la Recherche Scientifique (CNRS), Laura Alberici, Filippo Antonacci, Alessandro Arena, Angela Belvedere, Fabio Bernagozzi, Paolo Bernante, Pietro Bertoglio, Lorenzo Bianchi, Maria Bisulli, Barbara Bonfanti, Safia Boussedra, Jury Brandolini, Crescenzo Cacciapuoti, Stefano Cardelli, Riccardo Casadei, Matteo Cescon, Alessandro Cipolli, Riccardo Cipriani, Alfredo Conti, Luca Contu, Francesco Costa, Niccolo’ Daddi, Eugenia De Crescenzo, Pierandrea De Iaco, Alessandra De Palma, Massimo Del Gaudio, Anna Nunzia Della Gatta, Giampiero Dolci, Giulia Dondi, Matteo Droghetti, Sergio Nicola Forti Parri, Elena Garelli, Chiara Gelati, Giuliana Germinario, Federico A. Giorgini, Carlo Ingaldi, Elio Jovine, Kenji Kawamukai, Antonio Lanci Lanci, Raffaele Lombardi, Maria Elisa Lozano Miralles, Claudio Marchetti, Michele Masetti, Francesco Minni, Daniele Morezzi, Daniele Parlanti, Alice Pellegrini, Anna Myriam Perrone, Anna paola Pezzuto, Marco Pignatti, Gianluigi Pilu, Valentina Pinto, Gilberto Poggioli, Silvana Bernadetta Puglisi, Diego Raimondo, Matteo Ravaioli, Claudio Ricci, Sara Ricciardi, Francesco Ricotta, Roberta Rizzo, Angela Romano, Matteo Rottoli, Riccardo Schiavina, Renato Seracchioli, Matteo Serenari, Margherita Serra, Leonardo Solaini, Piergiorgio Solli, Gioia Sorbi, Mario Taffurelli, Marta Tanzanu, Achille Tarsitano, Marco Tesei, Gabriele Vago, Tommaso Violante, Simone Zanotti, Tommaso Frisoni, pignatti marco, ERSÖZ, CEVPER, GlobalSurg Collaborative, COVIDSurg Collaborative, Nepogodiev, Dmitri, Simoes, Joana F. F., Glasbey, James C., Alser, Osaid, Boccalatte, Luis A., Calvache, Jose A., Duran, Irani, Elhadi, Muhammed, Elmujtaba, Mohammed, Emile, Sameh, Harrison, Ewen M., Hutchinson, Peter, Allen Ingabire, J. C., Isik, Arda, Kamarajah, Sivesh K., Karandikar, Sharad, Kauppila, Joonas H., Kembuan, Gabriele, Lederhuber, Han, Löffler, Markus W., Mann, Harvinder, Marson, Ella J., Mclean, Kenneth A., Munyaneza, Emmanuel, Norman, Lisa, Omar, Omar M., Pius, Riinu, Pockney, Peter, Rutegård, Martin, Stewart, Grant D., Taylor, Elliott H., Venn, Mary L., Aizza, Giada, Bellio, Gabriele, Bogoni, Selene, Bortul, Marina, Casagranda, Biagio, Cortinovis, Sara, de Manzini, Nicolo', Drigo, Davide, Germani, Paola, Mastronardi, Manuela, Paiano, Lucia, Palmisano, Silvia, Nepogodiev, D, Bhangu, A, Gallo, G, Picciariello, P, Abushanab, M, Fruscio, R, Ornaghi, S, Iovino, C, Rossi, S, and Simonelli, F
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Male ,COVID-19 Vaccine ,safe surgery ,vaccination modelling ,COVID-19 ,Vascular damage Radboud Institute for Health Sciences [Radboudumc 16] ,MULTICENTER ,Comorbidity ,030230 surgery ,0302 clinical medicine ,phase 3 clinical trial (topic) ,Case fatality rate ,Prospective Studies ,SARS-CoV-2 , Vaccination , Safe surgery ,COVID-19/epidemiology ,SARS-CoV-2 ,vaccination ,education.field_of_study ,case fatality rate ,Vaccination ,Adolescent ,Adult ,Aged ,COVID-19 Vaccines ,Elective Surgical Procedures ,Female ,Humans ,Middle Aged ,Postoperative Complications ,Preoperative Period ,Young Adult ,health care policy ,030220 oncology & carcinogenesis ,cancer ,outcome ,mortality ,infection ,modelling ,Cohort study ,prospective study ,Human ,medicine.medical_specialty ,Article ,03 medical and health sciences ,SARS-CoV-2, vaccination ,SDG 3 - Good Health and Well-being ,COVID-19 Vaccines/pharmacology ,Vaccination/methods ,Elective surgery ,education ,Science & Technology ,Elective Surgical Procedure ,adult ,aged ,cancer grading ,cancer surgery ,computer assisted tomography ,elective surgery ,female ,follow up ,human ,incidence ,infection rate ,infection risk ,major clinical study ,male ,middle aged ,outcome assessment ,preoperative care ,sensitivity analysis ,seroprevalence ,Severe acute respiratory syndrome coronavirus 2 ,young adult ,surgery ,Cura preoperatòria ,Prospective Studie ,Surgery ,Human medicine ,Postoperative Complication ,610 Medizin und Gesundheit ,AcademicSubjects/MED00910 ,Settore MED/18 - CHIRURGIA GENERALE ,Settore MED/29 - CHIRURGIA MAXILLOFACCIALE ,ESTUDOS PROSPECTIVOS ,Vacunació ,Prospective cohort study ,Incidence (epidemiology) ,covid ,Elective Surgical Procedures/methods ,COVID, vaccination ,Original Article ,AcademicSubjects/MED00010 ,Life Sciences & Biomedicine ,international prospective cohort study ,Postoperative Complications/prevention & control ,Population ,SARS-CoV-2/immunology ,NO ,medicine ,ddc:610 ,LS7_4 ,business.industry ,Number needed to vaccinate ,Preoperative care ,3126 Surgery, anesthesiology, intensive care, radiology ,Settore MED/18 ,Reconstructive and regenerative medicine Radboud Institute for Health Sciences [Radboudumc 10] ,Emergency medicine ,business ,[SDV.MHEP]Life Sciences [q-bio]/Human health and pathology - Abstract
Background Preoperative SARS-CoV-2 vaccination could support safer elective surgery. Vaccine numbers are limited so this study aimed to inform their prioritization by modelling. Methods The primary outcome was the number needed to vaccinate (NNV) to prevent one COVID-19-related death in 1 year. NNVs were based on postoperative SARS-CoV-2 rates and mortality in an international cohort study (surgical patients), and community SARS-CoV-2 incidence and case fatality data (general population). NNV estimates were stratified by age (18–49, 50–69, 70 or more years) and type of surgery. Best- and worst-case scenarios were used to describe uncertainty. Results NNVs were more favourable in surgical patients than the general population. The most favourable NNVs were in patients aged 70 years or more needing cancer surgery (351; best case 196, worst case 816) or non-cancer surgery (733; best case 407, worst case 1664). Both exceeded the NNV in the general population (1840; best case 1196, worst case 3066). NNVs for surgical patients remained favourable at a range of SARS-CoV-2 incidence rates in sensitivity analysis modelling. Globally, prioritizing preoperative vaccination of patients needing elective surgery ahead of the general population could prevent an additional 58 687 (best case 115 007, worst case 20 177) COVID-19-related deaths in 1 year. Conclusion As global roll out of SARS-CoV-2 vaccination proceeds, patients needing elective surgery should be prioritized ahead of the general population., The aim of this study was to inform vaccination prioritization by modelling the impact of vaccination on elective inpatient surgery. The study found that patients aged at least 70 years needing elective surgery should be prioritized alongside other high-risk groups during early vaccination programmes. Once vaccines are rolled out to younger populations, prioritizing surgical patients is advantageous.
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- 2021
6. Does Amount of Intra-abdominal Fluid on CT May Predict Failure of Non-operative Management in Patients with Small Bowel Obstruction?
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Nir, Y., primary, Hershkovitz, Y., additional, Askenazi, I., additional, Dykman, D., additional, and Jeroukhimov, I., additional
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- 2021
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7. Thoracic vertebrae fracture: Is it an indicator of abdominal injury?
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Hershkovitz, Y., primary, Sheffer, D., additional, Peleg, K., additional, Kessel, B., additional, Dubose, J.J., additional, Jeroukhimov, I., additional, Givon, A., additional, Dudkiewicz, M., additional, and Aranovich, D., additional
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- 2021
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8. Time to surgery: Is it truly crucial in initially stable patients with penetrating injury?
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Hershkovitz, Y, primary, Bodas, M, additional, Givon, A, additional, and Kessel, B, additional
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- 2021
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9. Should the management approach to the anterior abdominal stab wound be different in patients with self-inflicted abdominal injury?
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Hershkovitz, Y., primary, Ashkenazi, I., additional, Kalman, I., additional, Peleg, K., additional, Bodas, M., additional, Givon, A., additional, Shapira, Z., additional, and Jeroukhimov, I., additional
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- 2021
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10. Measuring symptoms and diagnosing mental disorders in the elderly community: the test–retest reliability of the CIDI65+
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HANS ULRICH WITTCHEN, H. U. STREHLE J., Gerschler, A., Volkert, J., Dehoust, M. C., Sehner, S., Wegscheider, K., Ausìn, B., Canuto, A., Crawford, M., DA RONCH, Chiara, Grassi, Luigi, Hershkovitz, Y., Munoz, M., Quirk, A., Rotenstein, O., SANTOS OLMO, A. B., Shalev, A., Weber, K., Schulz, H., Härter, M., and Andreas, S.
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reliability ,CIDI ,assessment ,depression ,anxiety ,addiction ,elderly ,Mental disorders ,Socio-culturale - Published
- 2015
11. 681. Incidence and trends of gastrointestinal malignancies in Jewish and Arab populations in Israel: A 32-year review
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Hershkovitz, Y., primary, Lavy, R., additional, Keinan-Boker, L., additional, and Halevy, A., additional
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- 2016
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12. 399. A comparative study on two different methods to retrieve lymph node following gastrectomy
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Lavy, R., primary, Hershkovitz, Y., additional, Kapiev, A., additional, Chikman, B., additional, Yarom, N., additional, Sandbank, J., additional, and Halevy, A., additional
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- 2014
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13. 233. Lymph node retrieval using the acetone clearing method
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Lavy, R., primary, Shapira, Z., additional, Hershkovitz, Y., additional, Sandbank, J., additional, and Halevy, A., additional
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- 2014
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14. APPLICATION OF AERIAL DIGITAL PHOTOGRAPHY FOR MACROPHYTE COVER AND COMPOSITION SURVEY IN SMALL RURAL STREAMS
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Anker, Y., primary, Hershkovitz, Y., additional, Ben Dor, E., additional, and Gasith, A., additional
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- 2013
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15. APPLICATION OF AERIAL DIGITAL PHOTOGRAPHY FOR MACROPHYTE COVER AND COMPOSITION SURVEY IN SMALL RURAL STREAMS.
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Anker, Y., Hershkovitz, Y., Ben Dor, E., and Gasith, A.
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MACROPHYTES ,AERIAL photography ,DIGITAL photography ,NASTURTIUM (Genus) ,FLUVIAL geomorphology - Abstract
ABSTRACT Macrophytes are a key biological component in many fluvial ecosystems. In altered streams, they can become highly dominant features, covering extensive parts of the channel with cascading effects on stream conditions and biological composition. The aim of this study is to examine the possibility of using information collected by aerial digital photography-spectral analysis (ADP-SA) as an alternative, cost-effective methodology to the commonly used spectral procedure at a large (section) scale, and to the ground level visual survey (gridded frame) at a smaller (organism) scale. Cladophora glomerata and Nasturtium officinale, were selected as the targeted macrophyte species and classified at the same time (species relative cover) by using the three methodologies. Our findings show that the ADP-SA methodology was able to detect species and relative cover in similar accuracy (≤10% differences) at the two spatial scales. ADP-SA had a better spatial resolution than both the hyperspectral and the visual methodology (4 cm vs. 1 m and 10 cm, respectively) and was capable to differentiate submerged from emergent plants. However, on a smaller scale, ground level work is suitable and essential for detecting rarer species and is not hindered by weather, canopy cover or multi-layered plant composition. ADP-SA can therefore add a cost-effective and nonsubjective practice to the existing tool kit of macrophyte surveys, particularly in small streams, which require high spatial resolution. Copyright © 2013 John Wiley & Sons, Ltd. [ABSTRACT FROM AUTHOR]
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- 2014
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16. Another look at universal data compression.
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Ziv, J. and Hershkovitz, Y.
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- 1994
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17. Myocarditis after BNT162b2 mRNA Vaccine against Covid-19 in Israel.
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Mevorach, D., Anis, E., Cedar, N., Bromberg, M., Haas, E. J., Nadir, E., OIsha-Castell, S., Arad, D., Hasin, T., Levi, N., Asleh, R., Amir, O., Meir, K., Cohen, D., Dichtiar, R., Novick, D., Hershkovitz, Y., Dagan, R., Leitersdorf, I., and Ben-Ami, R.
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Background: Approximately 5.1 million Israelis had been fully immunized against coronavirus disease 2019 (Covid-19) after receiving two doses of the BNT162b2 messenger RNA vaccine (Pfizer-BioNTech) by May 31, 2021. After early reports of myocarditis during adverse events monitoring, the Israeli Ministry of Health initiated active surveillance.Methods: We retrospectively reviewed data obtained from December 20, 2020, to May 31, 2021, regarding all cases of myocarditis and categorized the information using the Brighton Collaboration definition. We analyzed the occurrence of myocarditis by computing the risk difference for the comparison of the incidence after the first and second vaccine doses (21 days apart); by calculating the standardized incidence ratio of the observed-to-expected incidence within 21 days after the first dose and 30 days after the second dose, independent of certainty of diagnosis; and by calculating the rate ratio 30 days after the second dose as compared with unvaccinated persons.Results: Among 304 persons with symptoms of myocarditis, 21 had received an alternative diagnosis. Of the remaining 283 cases, 142 occurred after receipt of the BNT162b2 vaccine; of these cases, 136 diagnoses were definitive or probable. The clinical presentation was judged to be mild in 129 recipients (95%); one fulminant case was fatal. The overall risk difference between the first and second doses was 1.76 per 100,000 persons (95% confidence interval [CI], 1.33 to 2.19), with the largest difference among male recipients between the ages of 16 and 19 years (difference, 13.73 per 100,000 persons; 95% CI, 8.11 to 19.46). As compared with the expected incidence based on historical data, the standardized incidence ratio was 5.34 (95% CI, 4.48 to 6.40) and was highest after the second dose in male recipients between the ages of 16 and 19 years (13.60; 95% CI, 9.30 to 19.20). The rate ratio 30 days after the second vaccine dose in fully vaccinated recipients, as compared with unvaccinated persons, was 2.35 (95% CI, 1.10 to 5.02); the rate ratio was again highest in male recipients between the ages of 16 and 19 years (8.96; 95% CI, 4.50 to 17.83), with a ratio of 1 in 6637.Conclusions: The incidence of myocarditis, although low, increased after the receipt of the BNT162b2 vaccine, particularly after the second dose among young male recipients. The clinical presentation of myocarditis after vaccination was usually mild. [ABSTRACT FROM AUTHOR]- Published
- 2021
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18. Early pregnancy confirmation--the role of urine pregnancy test in military primary care clinics.
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Hochman E, Elami-Suzin M, Soferman HG, Galil T, Hershkovitz Y, Tzur D, Derazne E, Elad H, Hochman, Eldar, Elami-Suzin, Matan, Soferman, Hagar Gur, Galil, Tamar, Hershkovitz, Yehuda, Tzur, Dorit, Derazne, Estela, and Elad, Hadar
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Pregnancy detection is a common procedure in primary care and can be challenging in the setting of military primary care clinics. The objective of this study was to determine whether the introduction of urine pregnancy tests to military primary care clinics is associated with earlier pregnancy detection. We conducted a cross-sectional study using data from female soldiers, aged 18 to 20 years. Pregnancy was diagnosed using urine pregnancy tests. Ultrasonographic gestational age at presentation was compared between pregnant soldiers diagnosed in primary care clinics and pregnant soldiers diagnosed in gynecology secondary care clinics. A total of 150 female soldiers performed urine pregnancy tests in 5 different primary care clinics, from which 28 (19%) were pregnant. Mean gestational age at diagnosis was significantly lower among patients diagnosed in primary care clinics as compared with patients diagnosed in gynecology secondary care clinics (41.07 days (SD, 6.72) vs. 48.42 days (SD, 21.94), p < 0.001). In conclusion, the availability of urine pregnancy tests in the setting of military primary care clinics was strongly associated with early pregnancy detection at a time point in which presentation for both antenatal care and abortion services potentially improve maternal and neonatal health. [ABSTRACT FROM AUTHOR]
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- 2012
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19. DNAqua-Net: Developing new genetic tools for bioassessment and monitoring of aquatic ecosystems in Europe
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Jóhannes Guðbrandsson, Peter M. Hollingsworth, Berry van der Hoorn, Irma Vitonytė, Per Sundberg, Agnès Bouchez, Snaedis H. Bjornsdottir, Pavel Stoev, Lyubomir Penev, Vallo Mulk, Trude Vrålstad, Daniel Hering, Ana Rotter, Adam Petrusek, Mary Kelly-Quinn, Jeremy J. Piggott, Emre Keskin, Zuzana Ciamporova-Zatovicova, Martin Pfannkuchen, Astrid Schmidt-Kloiber, Matteo Montagna, Baruch Rinkevich, Martyn Kelly, Roman Wenne, Filipe O. Costa, Atle M. Bones, Diego Fontaneto, Marlen Vasquez Hadjilyra, Maja Mejdandzic, Sigitas Šulčius, Craig R. Primmer, Patricia Mergen, Wolfram Graf, Jan Pawlowski, Alice Valentini, Lieven Bervoets, Belma Kalamujić Stroil, Florian Leese, Costas S. Tsigenopoulos, Kristian Meissner, Frédéric Rimet, Zrinka Ljubešić, Torbjørn Ekrem, Arjen G. C. L. Speksnijder, Kristel Panksep, Marieta Costache, Maria Kahlert, Panagiotis Kasapidis, Bella Japoshvili, Zoltán Csabai, Alexander M. Weigand, Michael Grabowski, Kessy Abarenkov, Wolfgang Wägele, Kristy Deiner, Michael Traugott, Jonas Zimmermann, Jens Carlsson, Anne Winding, Yaron Hershkovitz, Gábor Várbíró, Bojana Zegura, Judit Padisák, Urmas Kõljalg, Florian Altermatt, Elvira Mächler, Jean-François Flot, John Jones, Micaela Hellström, Dirk Steinke, Andrew R. Mahon, Georgina Mircheva, Stina Drakare, Simon Creer, Alfried P. Vogler, Pedro Segurado, Ion Năvodaru, Ángel DelValls, Pedro Beja, Andreja Naumoski, Irena Maček, Marketa Marečková, Pierre Taberlet, J.R. Viguri, Stefano Fazi, Ángel Borja, Malin Strand, Eric Coissac, Guy Woodward, Vera G. Fonseca, Snæbjörn Pálsson, Tina Elersek, Angela Boggero, Cene Fišer, Xavier Turon, Christian Moritz, Fedor Čiampor, Vojislava Bursić, Kat Bruce, Pieter Boets, Sofia Alexandra Ferreira Duarte, European Commission, Leese, F., Altermatt, F., Bouchez, A., Ekrem, T., Hering, D., Meissner, K., Mergen, P., Pawlowski, J., Piggott, J. J., Rimet, F., Steinke, D., Taberlet, P., Weigand, A. M., Abarenkov, K., Beja, P., Bervoets, L., Björnsdóttir, S., Boets, P., Boggero, A., Magnar Bones, A., Borja, Á., Bruce, K., Bursić, V., Carlsson, J., Čiampor, F., Čiamporová-Zatovičová, Z., Coissac, E., Costa, F., Costache, M., Creer, S., Csabai, Z., Deiner, K., Delvalls, Á., Drakare, S., Duarte, S., Eleršek, T., Fazi, S., Fišer, C., Flot, J. F., Fonseca, V., Fontaneto, D., Grabowski, M., Graf, W., Guðbrandsson, J., Hershkovitz, Y., Hollingsworth, P., Japoshvili, B., Jones, J. I., Kahlert, M., Kalamujic Stroil, B., Kasapidis, P., Kelly, M. G., Kelly- Quinn, M., Keskin, E., Kõljalg, U., Ljubešić, Z., Maček, I., Mächler, E., Mahon, A., Marečková, M., Mejdandzic, M., Mircheva, G., Montagna, M., Moritz, C., Mulk, V., Naumoski, A., Navodaru, I., Padisák, J., Pálsson, S., Panksep, K., Penev, L., Petrusek, A., Pfannkuchen, M. A., Primmer, C. R., Rinkevich, B., Rotter, A., Schmidt-Kloiber, A., Segurado, P., Speksnijder, A., Stoev, P., Strand, M., Šulčius, S., Traugott, M., Tsigenopoulos, C., Turon, X., Valentini, A., van der Hoorn, B., Várbíró, G., Vasquez Hadjilyra, M. I., Viguri, J., Vitonytė, I., Vogler, A., Vrålstad, T., Wägele, W., Wenne, R., Winding, A., Woodward, G., Zegura, B., Zimmermann, J., [et al.], Universidad de Cantabria, and Universidade do Minho
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DNAqua-Net ,genetic tools ,bioassessment ,monitoring ,0106 biological sciences ,0301 basic medicine ,Emerging technologies ,Ecology (disciplines) ,water ,Biodiversity ,dna ,Biology ,010603 evolutionary biology ,01 natural sciences ,Training (civil) ,Task (project management) ,taxonomy ,03 medical and health sciences ,14. Life underwater ,lcsh:Science ,Ecology ,business.industry ,Aquatic ecosystem ,Environmental resource management ,Environmental Sciences (social aspects to be 507) ,General Medicine ,Directive ,6. Clean water ,030104 developmental biology ,Conceptual framework ,Génétique, cytogénétique ,13. Climate action ,Systématique des espèces [zoologie] ,metabarcoding ,lcsh:Q ,business - Abstract
24 páginas, 2 figuras, 1 tabla., The protection, preservation and restoration of aquatic ecosystems and their functions are of global importance. For European states it became legally binding mainly through the EUWater Framework Directive (WFD). In order to assess the ecological status of a given water body, aquatic biodiversity data are obtained and compared to a reference water body. The quantified mismatch obtained determines the extent of potential management actions. The current approach to biodiversity assessment is based on morpho-taxonomy. This approach has many drawbacks such as being time consuming, limited in temporal and spatial resolution, and error-prone due to the varying individual taxonomic expertise of the analysts. Novel genomic tools can overcome many of the aforementioned problems and could complement or even replace traditional bioassessment. Yet, a plethora of approaches are independently developed in different institutions, thereby hampering any concerted routine application. The goal of this Action is to nucleate a group of researchers across disciplines with the task to identify gold-standard genomic tools and novel ecogenomic indices for routine application in biodiversity assessments of European fresh- and marine water bodies. Furthermore, DNAqua-Net will provide a platform for training of the next generation of European researchers preparing them for the new technologies. Jointly with water managers, politicians, and other stakeholders, the group will develop a conceptual framework for the standard application of eco-genomic tools as part of legally binding assessments.
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- 2016
20. Antibiotic Treatment Has No Influence on Anal Fistula Formation and Recurrent Perianal Abscess After Incision and Drainage of Cryptogenic Perianal Abscess: A Randomized Single-Blinded Prospective Study.
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Nasasra A, Hershkovitz Y, Ashkenazi I, Hammerschlag J, Zmora O, and Jeroukhimov I
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- Humans, Male, Female, Single-Blind Method, Adult, Middle Aged, Prospective Studies, Anus Diseases surgery, Anus Diseases microbiology, Treatment Outcome, Amoxicillin-Potassium Clavulanate Combination therapeutic use, Postoperative Complications epidemiology, Rectal Fistula etiology, Rectal Fistula surgery, Rectal Fistula drug therapy, Drainage methods, Recurrence, Abscess surgery, Abscess etiology, Anti-Bacterial Agents therapeutic use
- Abstract
Background: Anal fistula commonly appears after incision and drainage of a perianal abscess. Theoretically, a fistula develops as a consequence of the infection process. Antibiotic treatment was suggested to decrease the possibility of fistula development., Objective: We hypothesized that antibiotic treatment has no influence on the development of anal fistula after surgical treatment of perianal abscess., Design: A single-blinded randomized prospective study., Settings: Patients with primary cryptogenic abscesses were eligible to participate., Patients: Patients were divided into 2 groups. Patients in group I received amoxicillin 875 mg/clavulanic acid 125 mg during 7 days after surgery, and patients in group II received no antibiotics. The study database included demographics and clinical and laboratory data., Main Outcome Measures: Patients were examined in our outpatient clinic 2 weeks, 4 months, and 1 year after surgery, and a telephone questionnaire was performed 6 months after surgery. The primary outcome was the formation of anal fistula. The secondary outcome was recurrent perianal abscess., Results: Overall, 98 patients completed the study. Groups were not different in inclusion. Anal fistula was diagnosed in 16 patients (16.3%) in group I (treatment group) and 10 patients (10.2%) in group II (control group; p = 0.67). Nine patients (9.2%) developed recurrent perianal abscess, 4 in the treatment group and 5 in the control group ( p = 0.73)., Limitations: A relatively small number of patients were treated in a single medical center., Conclusion: Antibiotic therapy has no influence on anal fistula or recurrent perianal abscess formation after incision and drainage of perianal abscess. See Video Abstract ., El Tratamiento Con Antibiticos No Tiene Influencia En La Formacin De Fstula Anal Y En El Absceso Perianal Recurrente Despus De La Incisin Y Drenaje De Un Absceso Perianal Criptognico Un Estudio Prospectivo Aleatorizado, Simple Ciego: ANTECEDENTES:La fístula anal comúnmente aparece después de la incisión y drenaje de un absceso perianal. Teóricamente, la fístula se desarrolla como consecuencia del proceso infeccioso. Se sugirió tratamiento antibiótico para disminuir la posibilidad de desarrollo de fístula.OBJETIVO:Hipotetizamos que el tratamiento con antibióticos no tiene influencia en el desarrollo de fístula anal después del tratamiento quirúrgico del absceso perianal.DISEÑO:Estudio prospectivo, aleatorio, simple ciego.AJUSTE Y PACIENTES:Los pacientes con absceso criptogénico primario fueron elegibles para participar. Los pacientes se dividieron en dos grupos. Los pacientes del Grupo I recibieron amoxicilina 875 mg/ácido clavulánico 125 mg durante los 7 días posteriores a la cirugía y los pacientes del Grupo II no recibieron antibióticos. La base de datos del estudio incluyó datos demográficos, clínicos y de laboratorio.PRINCIPALES MEDIDAS DE RESULTADO:Los pacientes fueron examinados en nuestra clínica ambulatoria 2 semanas, cuatro meses y 1 año después de la cirugía y se realizó un cuestionario telefónico 6 meses después de la cirugía. El resultado primario fue la formación de una fístula anal. El resultado secundario fue el absceso perianal recurrente.RESULTADOS:En total, 98 pacientes completaron el estudio. Los grupos no fueron diferentes en cuanto a la inclusión. Se diagnosticó fístula anal en 16 (16,3%) pacientes del Grupo I (grupo de tratamiento) y 10 (10,2%) pacientes del Grupo II (grupo control) (p = 0,67). Nueve pacientes (9,2%) desarrollaron absceso perianal recurrente, 4 en el grupo de tratamiento y 5 en el grupo control (p = 0,73).LIMITACIONES:Número relativamente pequeño de pacientes tratados en un solo centro médico.CONCLUSIÓN:La terapia con antibióticos no tuvo influencia sobre la fístula anal o la formación de absceso perianal recurrente después de la incisión y drenaje del absceso perianal. (Traducción - Dr. Fidel Ruiz Healy )., (Copyright © The ASCRS 2024.)
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- 2024
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21. Laparoscopic Gastrojejunostomy Versus Endoscopic Stenting as a Palliative Treatment for Gastric Outlet Obstruction.
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Moscovici A, Hershkovitz Y, Shamah S, Peleg N, Lavy R, and Ben-Yehuda A
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- Humans, Male, Female, Retrospective Studies, Middle Aged, Aged, Length of Stay statistics & numerical data, Adult, Gastric Outlet Obstruction surgery, Gastric Outlet Obstruction etiology, Palliative Care methods, Stents, Laparoscopy methods, Gastric Bypass methods
- Abstract
Introduction: Gastric outlet obstruction (GOO) is a common complication in advanced stage upper gastrointestinal malignancies. The symptoms of severe nausea and protracted vomiting can lead to a decline in quality of life and cachexia. Symptoms of GOO can be effectively managed with either operative or nonoperative palliative interventions. In our article, we aim to compare laparoscopic gastrojejunostomy (GJ) to endoscopic stenting as palliative interventions for GOO. Methods: We retrospectively evaluated the charts of patients who underwent palliative procedure for gastric outlet obstruction. Group I included patients who underwent endoscopic stenting, and group II patients underwent Laparoscopic GJ. The groups' demographics (age, gender), length of procedure, length of stay, days to oral intake, overall survival, complications rate, and 30-day mortality rates were compared. Results: Overall, 38 patients were included in the study. Nineteen patients underwent endoscopic stenting and 19 underwent laparoscopic GJ. Comparing the groups, no significant differences were noted. Surgical time was significantly longer than the endoscopic procedures (83 minutes versus 25 minutes, P = .001). No significant differences were noted in days of oral intake initiation, overall survival and 30-day mortality rates. Five patients in the stenting group had complications (26.3%) versus none in the surgical group ( P = .046). No postoperative complications were noted. Conclusion: Laparoscopic GJ is a safe and feasible treatment for GOO, demonstrating early resumption of oral intake. The relative short hospital stay, combined with an encouraging postoperative complications profile and low reintervention rate, should be kept in mind especially among patients with longer life expectancy.
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- 2024
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22. Should Advanced Age Preclude Surgical Treatment of Gastrointestinal Stromal Tumor?
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Ben Yehuda A, Hammerschlag J, Jeroukhimov I, Markman O, Lavy R, and Hershkovitz Y
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- Humans, Female, Male, Aged, Age Factors, Middle Aged, Retrospective Studies, Aged, 80 and over, Treatment Outcome, Adult, Elective Surgical Procedures methods, Postoperative Complications epidemiology, Gastrointestinal Stromal Tumors surgery, Gastrointestinal Stromal Tumors pathology, Gastrointestinal Neoplasms surgery, Gastrointestinal Neoplasms pathology
- Abstract
Introduction: Surgical resection is a gold standard treatment for gastrointestinal stromal tumors (GISTs). It can be performed by minimally invasive surgery approach in most of the patients. It has been shown that advanced age is not a clear poor prognostic factor in patients who underwent surgery for GIST. We hypothesized that elderly patients undergo elective surgery less often compared to younger population. We aim to evaluate the safety, efficacy and oncological results of GIST treatment in the elderly population in our Medical Center. Materials and Methods: All patients who underwent surgery for GIST in Shamir Medical Center from January 1, 2016, to July 31, 2023, were included in the study. The patients were divided into 2 groups. Group 1 included patients younger than 75 years, while patients older than 75 years were included in Group 2. The groups were compared according to demographics, clinical and surgical parameters, complications, and pathology results. Results: Overall, 49 patients were included in the study. Group 1 included 28 patients and Group 2 included 21 patients. Group 2 patients more often underwent emergency surgery (52.4% versus 14.3%, P < .05) and had increased open surgery rate (19% versus 0%, P < .05). No difference between the groups was noted in surgical parameters, complications, and length of hospital stay. Tumor size, number of mitoses, level of ki67%, and involvement of surgical margins were not significantly different. However, in Group 2 patients, tumor size was larger and there was a trend toward higher rate of ki67 > 5%. Conclusion: Elderly patients with GIST are less frequently undergoing electively surgery and relatively often undergo open surgery. Frequency of complications is similar in elderly patients compares to younger patients group.
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- 2024
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23. Age-dependent seasonality in the incidence of stroke: A 21-year population-based study.
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Libruder C, Yaari R, Fluss R, Hershkovitz Y, Ram A, Tanne D, Huppert A, and Zucker I
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- Humans, Incidence, Aged, Middle Aged, Adult, Male, Female, Israel epidemiology, Aged, 80 and over, Adolescent, Young Adult, Age Factors, Ischemic Stroke epidemiology, Cerebral Hemorrhage epidemiology, Hospitalization statistics & numerical data, Seasons, Stroke epidemiology, Ischemic Attack, Transient epidemiology
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Introduction: Seasonality in the incidence of stroke has been examined in numerous studies, yet data on whether it differs with age are limited. To fill this gap, we utilized a largescale dataset from Israel., Patients and Methods: We retrieved data of all hospitalizations for ischemic stroke (IS), transient ischemic attack (TIA) and intra cerebral hemorrhage (ICH) from 2000 to 2020. We maintained separate datasets for IS/TIA and ICH, divided into five age groups: 18-49, 50-59, 60-69, 70-79, and 80+. We modeled the monthly incidence using a generalized additive model. The seasonal effect was defined by the rate ratio (RR) of each month compared to the annual mean., Results: The analysis included 317,586 and 23,789 events of IS/TIA and ICH respectively. We found an interaction between age and seasonality, accounting for a phase shift with age in the seasonal pattern of IS/TIA incidence. For cases under 70 years, the peak was during summertime and the RRs increased with decreasing age, reaching 1.11 (95% CI 1.09-1.13) at the youngest age group. In contrast, among the elderly, a winter peak was observed and the RRs increased with age to 1.07 (95% CI 1.06-1.08) at the oldest age group. For ICH, a winter/autumn peak was identified and the RRs increased with age to 1.20 (95% CI 1.16-1.24)., Conclusions: Our finding of age-dependent seasonal patterns in the occurrence of stroke, suggests closer monitoring of cardiovascular risk factors during wintertime among elderly individuals. The mechanism governing the seasonal phase shift with age in IS/TIA incidence, requires further investigation., Competing Interests: Declaration of conflicting interestsThe author(s) declared no potential conflicts of interest with respect to the research, authorship, and/or publication of this article.
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- 2024
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24. Group A Streptococcus Carriage in Adults in Southern Israel: A Prospective Study.
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Adler L, Tzadok Zehavi O, Parizade M, Hershkovitz Y, Amran MM, Hoffman R, Hakmon Aronson T, Rotlevi E, Cohen B, and Yehoshua I
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- Adult, Child, Female, Humans, Adolescent, Young Adult, Middle Aged, Aged, Male, Prospective Studies, Israel epidemiology, Streptococcus pyogenes, Ambulatory Care Facilities, Ethnicity
- Abstract
Background: The prevalence of Group A streptococcus (GAS) carriage among adults is studied less than in children. The variability of reported carriage rates is considerably large and differs among diverse geographic areas and populations., Objectives: To evaluate the prevalence of GAS carriage among adults in Israel., Methods: In this prospective study, conducted in a large healthcare maintenance organization in Israel, we obtained pharyngeal cultures from adults attending the clinic without upper respiratory tract complaints or fever. Patient data included sex, age, number of children, and religious sectors., Results: From May to December 2022, eight family physicians collected a total of 172 throat swabs (86% response rate). The median age was 37 years (range 18-65); 72.7% were females, 22.7% were ultra-Orthodox Jewish, and 69.2% had children. The prevalence of GAS carriage was 6.98%, 95% confidence interval (95%CI) 3.7%-11.9%. GAS carriers were younger (31.7 vs. 39.3 years, P = 0.046), and the majority were ultra-Orthodox Jews (58.3% vs. 20%, P = 0.006). All GAS carriers were from lower socioeconomic status. When assessing risk factors for GAS carriage using multivariate analysis, only being an ultra-Orthodox Jew was positively related to GAS carriage (adjusted odds ratio 5.6, 95%CI 1.67-18.8)., Conclusions: Being an ultra-Orthodox Jew was the single variable associated with a GAS carriage, which may be related to having many children at home and living in overcrowded areas. Primary care physicians in Israel should recognize this situation when examining patients with sore throats, mainly ultra-Orthodox Jews.
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- 2024
25. Urgent Paraesophageal Hernia: Can We Do Better?
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Hershkovitz Y, Ben Yehuda A, Dykman D, and Jeroukhimov I
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- Humans, Retrospective Studies, Herniorrhaphy methods, Hospitalization, Treatment Outcome, Hernia, Hiatal surgery, Hernia, Hiatal complications, Laparoscopy methods
- Abstract
Introduction: Paraesophageal hernia (PEH) is a relatively common pathology in the Western population. It may be asymptomatic, but ∼50% of patients with PEH have symptoms that may mimic gastrointestinal, respiratory, and cardiac pathology. Surgery is recommended in all acute cases of PEH, but indications for surgical intervention in asymptomatic or nonacutely symptomatic patient remain unclear. Purpose of this study was to evaluate our experience in management of patients with PEH admitted to the surgical word. Our special interest was in acute cases of emergency admission who were previously discharged from emergency room (ER). Methods: Data of patients who underwent PEH repair from January 1, 2017 to May, 2023, were retrospectively evaluated. Patients were divided into two groups. Group I included patients admitted through ER with acute symptoms of PEH. Patients who underwent elective surgery were included in group II. Group I patients were additionally divided on those who previously visited ER, and signs of PEH were underscored and those who were admitted to ER first time. Results: Ninety-eight patients underwent laparoscopic PEH repair. Group I included 28 patients (28.9%). Significant differences were noticed in patient's age, main complaint, and rate of complications. Fourteen patients from group I were previously discharged from ER, and in 12 of them, imaging study clearly showed diaphragmatic hernia. Conclusion: Patients who underwent elective laparoscopic PEH repair have better outcome. Signs of PEH may be underscored by ER physicians. Higher index of suspicion required to diagnose this relatively rare reason of ER admission.
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- 2024
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26. Laparoscopic Completion Total Gastrectomy for Remnant Gastric Cancer Compared to Laparoscopic Total Gastrectomy in Short- and Medium-Term Results.
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Hammerschlag J, Hershkovitz Y, Amos I, Lavy R, and Ben-Yehuda A
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- Humans, Middle Aged, Retrospective Studies, Gastrectomy methods, Lymph Nodes pathology, Postoperative Complications surgery, Treatment Outcome, Lymph Node Excision methods, Stomach Neoplasms surgery, Laparoscopy methods
- Abstract
Introduction: The incidence of remnant gastric cancer is increasing in recent years. The advantages of minimally invasive surgery for gastric cancer are well established. However, laparoscopic completion total gastrectomy for remnant gastric cancer harbors difficulties due to adhesions, changed configuration of the anatomical organs, and changes on the lymphatic flow. We aim to investigate the feasibility, safety, and the short-term outcomes of laparoscopic completion total gastrectomy compared to laparoscopic total gastrectomy. Materials and Methods: All patients who underwent total gastrectomy from January 2018 to December 2021 at Shamir Medical Center were included in the study. Patients were divided into two groups-completion gastrectomy and total gastrectomy. The groups were compared for demographics, operative, and clinical outcomes. Results: Overall, 22 patients were included in the study. Eight were completion gastrectomy following subtotal gastrectomy for malignancy and 14 were primary total gastrectomy. All operations were performed by minimal invasive surgery technique. Average age was 64 years, with no differences in gender. Two major intraoperative complications were noted in completion group (25% versus 0%, P = .12). Both length of surgery (3:03 versus 3:40, P = .049) and length of stay (7 days versus 9 days, P = .5) were shorter in completion group. There were fewer postoperative complications (12.5% versus 28.5%, P = .61). Average number of harvested lymph nodes was significantly lower in completion group (10 versus 33, P = .002). Conclusion: Laparoscopic completion total gastrectomy for remnant gastric cancer is safe and feasible having comparable oncological surrogate's parameters and recurrence profile. Clinical Registration Number: 0015-22-ASF.
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- 2023
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27. Successful ligelizumab treatment of severe refractory solar urticaria.
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Hershkovitz Y, Khanimov I, Rubin L, Dranitzki Z, Talmon A, Ribak Y, Shamriz O, Levi A, and Tal Y
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- Humans, Antibodies, Monoclonal, Humanized therapeutic use, Omalizumab therapeutic use, Urticaria, Solar, Urticaria drug therapy
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- 2023
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28. Adolescent Hypertension Is Associated With Stroke in Young Adulthood: A Nationwide Cohort of 1.9 Million Adolescents.
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Fishman B, Bardugo A, Zloof Y, Bendor CD, Libruder C, Zucker I, Lutski M, Ram A, Hershkovitz Y, Orr O, Omer M, Furer A, Goldman A, Yaniv G, Tanne D, Derazne E, Tzur D, Afek A, Grossman E, and Twig G
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- Male, Young Adult, Humans, Adolescent, Adult, Middle Aged, Female, Retrospective Studies, Risk Factors, Incidence, Hypertension epidemiology, Stroke epidemiology, Diabetes Mellitus, Ischemic Stroke
- Abstract
Background: Adult hypertension is a well-established risk factor for stroke in young adults (aged <55 years), and the effects are even more deleterious than at an older age. However, data are limited regarding the association between adolescent hypertension and the risk of stroke in young adulthood., Methods: A nationwide, retrospective cohort study of adolescents (aged 16-19 years) who were medically evaluated before compulsory military service in Israel during 1985 to 2013. For each candidate for service, hypertension was designated after constructed screening, and the diagnosis was confirmed through a comprehensive workup process. The primary outcome was ischemic and hemorrhagic stroke incidence as registered at the national stroke registry. Cox proportional-hazards models were used. We conducted sensitivity analyses by excluding people with a diabetes diagnosis at adolescence or a new diabetes diagnosis during the follow-up period, analysis of adolescents with overweight, and adolescents with baseline unimpaired health status., Results: The final sample included 1 900 384 adolescents (58% men; median age, 17.3 years). In total, 1474 (0.08%) incidences of stroke (1236 [84%] ischemic) were recorded, at a median age of 43 (interquartile range, 38-47) years. Of these, 18 (0.35%) occurred among the 5221 people with a history of adolescent hypertension. The latter population had a hazard ratio of 2.4 (95% CI, 1.5-3.9) for incident stroke after adjustment for body mass index and baseline sociodemographic factors. Further adjustment for diabetes status yielded a hazard ratio of 2.1 (1.3-3.5). We found similar results when the outcome was ischemic stroke with a hazard ratio of 2.0 (1.2-3.5). Sensitivity analyses for overall stroke, and ischemic stroke only, yielded consistent findings., Conclusions: Adolescent hypertension is associated with an increased risk of stroke, particularly ischemic stroke, in young adulthood., Competing Interests: Disclosures None.
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- 2023
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29. Chronic pain following totally extra-peritoneal inguinal hernia repair: a randomized clinical trial comparing glue and absorbable tackers.
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Jeroukhimov I, Dykman D, Hershkovitz Y, Poluksht N, Nesterenko V, Yehuda AB, Stephansky A, and Zmora O
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- Humans, Treatment Outcome, Single-Blind Method, Peritoneum, Pain, Postoperative etiology, Herniorrhaphy adverse effects, Herniorrhaphy methods, Surgical Mesh adverse effects, Recurrence, Chronic Pain etiology, Hernia, Inguinal surgery, Laparoscopy adverse effects, Laparoscopy methods
- Abstract
Purpose: Chronic pain following inguinal hernia repair occurs in up to 20% of patients. The underlying mechanism probably involves sensory nerve damage and abnormal healing that might be influenced by the materials chosen for mesh fixation. The main objective of this study was to compare glue and absorbable tackers on the rate of chronic pain after surgery in patients undergoing totally extraperitoneal inguinal hernia repair (TEP)., Methods: Patients undergoing (TEP) inguinal hernia repair were enrolled in a single-blind randomized clinical trial and were randomized for mesh fixation with glue (LIQUIBAND FIX 8 Neopharm) or absorbable tackers (SECURE STRAP Johnson & Johnson). Pain was assessed using a validated 4-point verbal-rank scale (none, mild, moderate, and severe) at 1 week, 1 month, 6 months, and 1 year postoperatively. Chronic pain was defined as pain persisting beyond 3 months., Results: Two hundred and eight patients were analyzed. The groups were similar in age, gender, and hernia side. Chronic pain of any intensity was reported in 31.7% (66/208) after 6 months and in 13% (29/208) after 12 months. No differences in postoperative pain were observed between the two forms of mesh fixation. Still, when only those with severe pain were considered, mesh fixation with glue resulted in less pain compared to fixation by tackers (log-rank p = 0.025). At 1 year, 4 symptomatic recurrent hernias were identified in patients whose mesh was fixated with absorbable tackers., Conclusions: Patients who underwent TEP inguinal hernia repair with mesh fixated by glue suffered from less pain., (© 2023. The Author(s), under exclusive licence to Springer-Verlag GmbH Germany, part of Springer Nature.)
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- 2023
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30. Effectiveness of BNT162b2 Vaccine against Omicron Variant Infection among Children 5-11 Years of Age, Israel.
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Glatman-Freedman A, Hershkovitz Y, Dichtiar R, Rosenberg A, Keinan-Boker L, and Bromberg M
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- Humans, Child, Israel epidemiology, BNT162 Vaccine, SARS-CoV-2, COVID-19 epidemiology, COVID-19 prevention & control, Vaccines
- Abstract
We assessed effectiveness of the BNT162b2 vaccine against infection with the B.1.1.529 (Omicron) variant (mostly BA.1 subvariant), among children 5-11 years of age in Israel. Using a matched case-control design, we matched SARS-CoV-2-positive children (cases) and SARS-CoV-2-negative children (controls) by age, sex, population group, socioeconomic status, and epidemiologic week. Vaccine effectiveness estimates after the second vaccine dose were 58.1% for days 8-14, 53.9% for days 15-21, 46.7% for days 22-28, 44.8% for days 29-35, and 39.5% for days 36-42. Sensitivity analyses by age group and period demonstrated similar results. Vaccine effectiveness against Omicron infection among children 5-11 years of age was lower than vaccine efficacy and vaccine effectiveness against non-Omicron variants, and effectiveness declined early and rapidly.
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- 2023
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31. Violence against women in Israel: injury mechanisms and clinical outcomes following hospitalization.
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Ashkenazi I, Givon A, Hershkovitz Y, Bodas M, and Jeroukhimov I
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- Male, Humans, Female, Israel epidemiology, Retrospective Studies, Violence, Injury Severity Score, Trauma Centers, Hospitalization, Wounds, Nonpenetrating therapy, Wounds, Nonpenetrating epidemiology
- Abstract
Purpose: The objective of this study was to evaluate the relative contributions of different mechanisms of assault to injury and mortality in women in Israel., Methods: We identified females hospitalized between 2011 and 2020 following an assault, secondary to blunt, stabbing, or shooting mechanisms of injury, in the Israeli Program for Registration of Trauma Patients (National Trauma Registry). To avoid bias due to temporary hospitalizations for non-medical reasons, we included patients with injuries graded as Abbreviated Injury Scale ≥ 2., Results: Females accounted for 8.1% (926/11,486) of assault patients in the study population. Compared to males, females were older (40.7 vs. 31.0 years; p < 0.001), more commonly injured by the blunt trauma mechanism (72.1 vs. 48.6%; p < 0.001), and more commonly injured at a place of residence (50.9 vs. 8.2%; p < 0.001). There were no differences in the number of body areas injured, severe Injury Severity Score, and median hospitalization. Males were operated more commonly (44.6 vs. 40.0%; p = 0.008). Mortality in females and males was similar (2.8 vs. 2.3%; p = 0.43). Secondary analysis revealed that blunt injuries were responsible for 61.2% of the severe cases (ISS ≥ 16), 61.4% of the operations, 54.9% of the Intensive Care Unit (ICU) admissions, and 53.8% of the mortality observed in females. When compared to males injured by blunt trauma, females injured by this mechanism were older (43.0 ± 24.7 vs. 32.8 ± 16.1 years; p < 0.001) and had higher mortality (2.1 vs. 0.9%; p = 0.007)., Conclusions: Assault by mechanisms other than stabbing and shooting should be recognized as a source of severe morbidity and mortality in females., (© 2022. The Author(s), under exclusive licence to Springer-Verlag GmbH Germany.)
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- 2023
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32. Vaccine Coverage Associated With Ending a Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Wave: A Retrospective Longitudinal Analysis.
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Glatman-Freedman A, Feldman SF, Hershkovitz Y, Kaufman Z, Dichtiar R, Keinan-Boker L, and Bromberg M
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- Humans, SARS-CoV-2, BNT162 Vaccine, Retrospective Studies, Communicable Disease Control, Vaccination, COVID-19 epidemiology, COVID-19 prevention & control, Vaccines
- Abstract
Background: Two SARS-CoV-2 waves in Israel ended while a substantial number of individuals remained unvaccinated or partially vaccinated. The indirect protective effect of the first BNT162b2 vaccination campaign in Israel was evaluated between 22 December 2020 and 18 May 2021., Methods: The daily percentage of new polymerase chain reaction (PCR)-confirmed SARS-CoV-2 cases among unvaccinated individuals was analyzed for trends. Major shifts were identified using piecewise linear regression analysis. At these shifts, the percentage of naturally vaccinated (past SARS-CoV-2 cases) and the percentage of actively vaccinated (by inoculation) individuals were weighted and summed to determine the percentage of natural and active vaccination (NAV)., Results: A first decline among unvaccinated individuals occurred during a lockdown period, when the percentage of NAV was 8.16%. The major decline occurred after the end of the lockdown when the percentage of NAV reached 52.05%. SARS-CoV-2 cases ultimately declined among unvaccinated individuals when the percentage of NAV reached 63.55%. During the study period, the Alpha variant was prevalent and the use of nonpharmaceutical interventions, including social distancing, existed to varying degrees., Conclusions: The vaccination campaign played a major role in the decline of SARS-CoV-2 infection among unvaccinated individuals, leading to the end of the first 2021 SARS-CoV-2 wave (Alpha variant) in Israel. Infection in unvaccinated individuals stopped when two-thirds of the population were naturally or actively vaccinated. Any change in characteristics of the virus or the population can lead to a new outbreak., Competing Interests: Potential conflicts of interest. The authors: No reported conflicts of interest. All authors have submitted the ICMJE Form for Disclosure of Potential Conflicts of Interest. Conflicts that the editors consider relevant to the content of the manuscript have been disclosed., (© The Author(s) 2022. Published by Oxford University Press on behalf of Infectious Diseases Society of America. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.)
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- 2023
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33. Particulate Air Pollution Exposure and Stroke among Adults in Israel.
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Gaines B, Kloog I, Zucker I, Ifergane G, Novack V, Libruder C, Hershkovitz Y, Sheffield PE, and Yitshak-Sade M
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- Humans, Female, Aged, Israel epidemiology, Environmental Exposure adverse effects, Environmental Exposure analysis, Particulate Matter analysis, Dust analysis, Cerebral Hemorrhage, Ischemic Attack, Transient, Air Pollution adverse effects, Air Pollution analysis, Stroke etiology, Stroke chemically induced, Ischemic Stroke, Myocardial Ischemia chemically induced, Air Pollutants analysis
- Abstract
Stroke is the second most common cause of death and disability in the world. Many studies have found fine particulate matter (PM
2.5 ) exposure to be associated with an increased risk of atherosclerotic cardiovascular disease, mostly focusing on ischemic heart disease and acute myocardial infarction. In a national analysis conducted in Israel-an area with unique climate conditions and high air pollution levels, we estimated the association between short-term PM2.5 exposure and ischemic stroke, intracerebral hemorrhage (ICH), or transient ischemic attacks (TIA). Using the Israeli National Stroke Registry, we obtained information on all stroke cases across Israel in 2014-2018. We obtained daily PM2.5 exposures from spatiotemporally resolved exposure models. We restricted the analytical data to days in which PM2.5 levels did not exceed the Israeli 24 h standard (37.5 µg/m3 ). We repeated the analysis with a stratification by sociodemographic characteristics and comorbidities. For all outcomes, the exposure-response curves were nonlinear. PM2.5 exposure was associated with a higher ischemic stroke risk, with larger effect estimates at higher exposure levels. Although nonsignificant, the exposure-response curve for TIA was similar. The associations with ICH were nonsignificant throughout the PM2.5 exposure distribution. The associations with ischemic stroke/TIA were larger among women, non-Jewish individuals, older adults, and individuals with diabetes, hypertension, and ischemic heart disease. In conclusion, short-term PM2.5 exposure is associated with a higher risk for ischemic stroke and possibly TIA, even when PM2.5 concentrations do not exceed the Israeli air quality guideline threshold. Vulnerability to the air pollution effects differed by age, sex, ethnicity, and comorbidities.- Published
- 2023
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34. An Increased Risk for Ischemic Stroke in the Short-Term Period following COVID-19 Infection: A Nationwide Population-Based Study.
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Libruder C, Hershkovitz Y, Ben-Yaish S, Tanne D, Keinan-Boker L, and Binyaminy B
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Introduction: The association disclosed between coronavirus disease 2019 (COVID-19) infection and ischemic stroke (IS) raises concern. The exact risk periods, which were not consistent between studies, require further investigation., Methods: We linked two national databases: the COVID-19 database and the Israeli National Stroke Registry. The self-controlled case series method was used to estimate the association between COVID-19 infection and a first IS. The study population included all Israeli residents who had both a first IS event and a first COVID-19 diagnosis during 2020. The date of the PCR test served to define the day of exposure, and the 28 days following it were categorized into three risk periods: days 1-7, 8-14, and 15-28. A relative incidence (RI) with a 95% confidence interval (95% CI) was calculated based on the incidence rate of events in a post-exposure period, compared to the incidence rate in a control period., Results: From January 1, 2020, to December 31, 2020, 308,015 Israelis aged 18+ were diagnosed with COVID-19 and 9,535 were diagnosed with a first IS. Linking the two databases, 555 persons had both diagnoses during 2020. The mean age of the study population was 71.5 ± 13.7, 55.1% were males, 77.8% had hypertension, 73.7% had hyperlipidemia, 51.9% had diabetes, and 28.5% had ischemic heart disease. Comparing the risk period and the control period, we found a very similar distribution of the cardiovascular risk factors. The risk for an acute IS was 3.3-fold higher in the first week following COVID-19 diagnosis, compared with a control period (RI = 3.3; 95% CI: 2.3-4.6). The RI among males (RI = 4.5; 95% CI: 2.9-6.8) was 2.2-fold higher compared to females. The increased risk did not last beyond the first week following exposure., Conclusion: Physicians should be aware of the elevated risk for IS among patients experiencing COVID-19, particularly among men with high burden of cardiovascular risk factors., (© 2023 S. Karger AG, Basel.)
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- 2023
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35. Gastrointestinal Stromal Tumor of the Appendix.
- Author
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Elnassasra A, Hershkovitz Y, Zager Y, and Lavy R
- Subjects
- Humans, Appendix surgery, Gastrointestinal Stromal Tumors diagnosis, Gastrointestinal Stromal Tumors surgery, Gastrointestinal Stromal Tumors pathology
- Published
- 2022
36. Myocarditis After BNT162b2 COVID-19 Third Booster Vaccine in Israel.
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Mevorach D, Anis E, Cedar N, Hasin T, Bromberg M, Goldberg L, Levi N, Perzon O, Magadle N, Barhoum B, Parnassa E, Dichtiar R, Hershkovitz Y, Green MS, Ash N, Keinan-Boker L, and Alroy-Preis S
- Subjects
- BNT162 Vaccine, Humans, Immunization, Secondary, Israel epidemiology, COVID-19 prevention & control, Myocarditis epidemiology, Myocarditis etiology
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- 2022
- Full Text
- View/download PDF
37. Shortening shift's length-Should we ask the residents if this is what they want?
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Hershkovitz Y, Rasco A, and Tal O
- Subjects
- Adult, Humans, Israel, Quality of Life, Surveys and Questionnaires, Internship and Residency, Physicians
- Abstract
Introduction: Work overload in hospitals enforced reducing shifts length of physicians in many countries over the last decade. In Israel, the current shift standard is of 26 hours, however, there is a residents' struggle alongside a governmental intent to short the shifts to 16 hour. We aim to evaluate residents and interns support and preferences regarding shortening shifts and their ramifications to quality of life and residency programs., Methods: A structured questionnaire was distributed to all resident and interns in a single center. We evaluated their current quality of residency and life, their support in the shorter shifts model, offering alternative program components such as reduced pay, longer residency or replacement in order to allow rest. We compared those who support the new model to those who objected to identify common characteristics to draw a resident profile for acceptance of change., Results: Overall, 151 physicians answer the questionnaire. 70.2% support the shorter shifts model. Residents above 35 years old and those reaching completion of residency, significantly less support the shortening shifts model. No other demographic nor professional parameters were different between the supporters and non-supporters. Option of reduced pay or longer residency dramatically reduced the support rate to less than 30% and 20%, respectively. Replacement by other physician (resident or senior physician) in order to allow rest was supported by only 40%., Conclusion: Residents' standpoints regarding a desirable change are crucial to plan a successful implementation. A national survey is required before a new model is introduced, to achieve an optimal transparent efficient process., Competing Interests: The authors have declared that no competing interests exist.
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- 2022
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38. Angiography in patients with pelvic fractures and contrast extravasation on CT following high-energy trauma.
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Hammerschlag J, Hershkovitz Y, Ashkenazi I, Shapira Z, and Jeroukhimov I
- Subjects
- Angiography methods, Extravasation of Diagnostic and Therapeutic Materials diagnostic imaging, Hemorrhage complications, Hemorrhage etiology, Humans, Retrospective Studies, Tomography, X-Ray Computed methods, Embolization, Therapeutic methods, Fractures, Bone complications, Pelvic Bones diagnostic imaging, Pelvic Bones injuries
- Abstract
Introduction: Pelvic fracture may be accompanied by severe bleeding. Computed tomography (CT) is a gold standard diagnostic tool in stable trauma patients. Contrast extravasation detected on CT of pelvis is a sign of hemorrhage, but its significance is not clear. We aimed to evaluate the need for angiography in patients with pelvic fracture and CT revealed contrast extravasation. We tried to identify parameters that might help to choose patients who will benefit from therapeutic angiography., Methods: Electronic medical records of patients with pelvic fracture admitted to Level II Trauma Center during 10 years were retrospectively reviewed. Patients who had contrast extravasation on CT were included. Data base consisted of demographics, injury severity, initial physiologic parameters, laboratory data, results of CT and angiography., Results: Forty out of 396 patients had contrast extravasation detected by CT. Twelve patients underwent angiography and 4 of them benefited from embolization. The sensitivity of contrast extravasation in evaluating the need for embolization was 1.0 (95% CI 0.398, 1.0), positive predictive value was 0.1 (95% CI 0.028, 0.237), and the negative predictive value was 1.0 (95% CI 0.990, 1.0)., Conclusion: The role of angiography in stable patients with pelvic fracture and CT identified contrast extravasation remains questionable. Most of these patients are not in need of angioembolization., (© 2021. Springer-Verlag GmbH, DE part of Springer Nature.)
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- 2022
- Full Text
- View/download PDF
39. Clinical Presentation of Acute Cholecystitis during the COVID-19 Outbreak.
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Hershkovitz Y, Zmora O, Nativ H, Ashkenazi I, Hammerschlag J, and Jeroukhimov I
- Subjects
- Aged, Disease Outbreaks, Female, Humans, Male, Middle Aged, Pandemics, Retrospective Studies, COVID-19, Cholecystitis, Acute diagnosis, Cholecystitis, Acute epidemiology, Cholecystitis, Acute therapy
- Abstract
Background: The coronavirus disease 2019 (COVID-19) pandemic has had a significant impact on healthcare systems worldwide. The fear of seeking medical attention to avoid the possibility of being infected may have altered the course of some diseases., Objectives: To describe our experience with the management of patients with acute cholecystitis during the pandemic at our medical center., Methods: We compared patients treated for acute cholecystitis between 1 March and 31 August 2020 (Group I) to patients admitted with the same diagnosis during the same months in 2019 (Group II). We evaluated demographics, presenting symptoms, laboratory and imaging findings at presentation, the disease's clinical course, management, and outcome., Results: Group I consisted of 101 patients and group II included 94 patients. No differences were noted for age (66 years, IQR 48-78 vs. 66 years, IQR 47-76; P = 0.50) and sex (57.4% vs. 51.1% females; P = 0.39) between the two groups. The delay between symptom onset and hospital admission was longer for Group I patients (3 days, IQR 2-7 vs. 2 days, IQR 1-3; P = 0.002). Moderate to severe disease was more commonly encountered in Group I (59.4% vs. 37.2%, P = 0.003). Group I patients more often failed conservative management (36% vs. 6%, P = 0.001) and had a higher conversion rate to open surgery (15.4% vs. 0%, P = 0.025)., Conclusions: Patients presenting with acute cholecystitis during the COVID-19 pandemic more often presented late to the emergency department and more showed adverse outcomes.
- Published
- 2022
40. Effectiveness of BNT162b2 Vaccine Booster against SARS-CoV-2 Infection and Breakthrough Complications, Israel.
- Author
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Glatman-Freedman A, Bromberg M, Hershkovitz Y, Sefty H, Kaufman Z, Dichtiar R, and Keinan-Boker L
- Subjects
- Aged, 80 and over, BNT162 Vaccine, COVID-19 Vaccines, Humans, Infant, Israel epidemiology, SARS-CoV-2, COVID-19 epidemiology, COVID-19 prevention & control
- Abstract
We estimated vaccine effectiveness (VE) of the BNT162b2 (Pfizer-BioNTech, https://www.pfizer.com) booster dose against SARS-CoV-2 infection and reduction of complications (hospitalization, severe disease, and death) among breakthrough cases in persons in Israel >16 years of age for <20 weeks. VE estimates reached 96.8% (95% CI 96.0%-97.5%) for persons 16-59 years of age and 93.1% (95% CI 91.8%-94.2%) for persons >60 years of age on week 3. VE estimates remained at these levels for 8 weeks in the 16-59 age group and 11 weeks in those >60. A slow decline followed, becoming more pronounced in the last 2-3 weeks of evaluation. Estimates in the last week of evaluation were 77.6% (95% CI 68.4%-84.2%) and 61.3% (52.5%-68.4%) for persons 16-59 years and >60 years, respectively. The more pronounced VE decline coincided with rapid increase in Omicron variant activity. Rate reduction of breakthrough complications remained moderate to high throughout the evaluation.
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- 2022
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41. Incidence and risk factors of mental disorders in the elderly: The European MentDis_ICF65+ study.
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Andreas S, Schulz H, Volkert J, Lüdemann J, Dehoust M, Sehner S, Suling A, Wegscheider K, Ausín B, Canuto A, Crawford MJ, Da Ronch C, Grassi L, Hershkovitz Y, Muñoz M, Quirk A, Rotenstein O, Belén Santos-Olmo A, Shalev A, Weber K, Wittchen HU, and Härter M
- Subjects
- Aged, Cross-Sectional Studies, Humans, Incidence, Prevalence, Risk Factors, Mental Disorders diagnosis, Quality of Life
- Abstract
Objective: While incidence rates of depression and anxiety disorders in the elderly have been comprehensively investigated, the incidence rates of other mental disorders have rarely been researched. The incidence rate and predictors of various mental disorders in the elderly were evaluated in different European and associated countries., Methods: A cross-sectional and longitudinal multi-centre survey of Diagnostic and Statistical Manual of Mental Disorders (4th ed.) diagnoses was conducted in different European and associated countries (Germany, Italy, Spain, Switzerland, the United Kingdom and Israel) to collect data on the prevalence and incidence of mental disorders in the elderly. The sample size of the longitudinal wave was N = 2592 elderly., Results: The overall 1-year incidence rate for any mental disorder in the elderly is 8.65%. At 5.18%, any anxiety disorder had the highest incidence rate across all diagnostic groups. The incidence rate for any affective disorder was 2.97%. The lowest incidence rates were found for agoraphobia (1.37%) and panic disorder (1.30%). Risk factors for the development of any mental disorder were never having been married, no religious affiliation, a higher number of physical illnesses and a lower quality of life., Conclusion: In comparison to other studies, lower incidence rates for any affective disorder and middle-range incidence for any anxiety disorder were found. To the authors' knowledge, no prior studies have reported 1-year incidence rates for somatoform disorder, bipolar disorder and substance misuse in community-dwelling elderly. These findings indicate the need to raise awareness of psychosocial problems in the elderly and to ensure adequate availability of mental health services.
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- 2022
- Full Text
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42. Correction to: Failure of observation and need for delayed tube thoracostomy in 197 unselected patients with occult pneumothorax: a retrospective study.
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Hershkovitz Y, Ashkenazi I, Dykman D, Shapira Z, and Jeroukhimov I
- Published
- 2022
- Full Text
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43. Failure of observation and need for delayed tube thoracostomy in 197 unselected patients with occult pneumothorax: a retrospective study.
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Hershkovitz Y, Ashkenazi I, Dykman D, Shapira Z, and Jeroukhimov I
- Subjects
- Chest Tubes, Humans, Retrospective Studies, Thoracostomy methods, Time-to-Treatment, Pneumothorax diagnostic imaging, Pneumothorax surgery, Thoracic Injuries diagnostic imaging, Thoracic Injuries surgery, Wounds, Nonpenetrating diagnostic imaging, Wounds, Nonpenetrating surgery
- Abstract
Introduction: Occult pneumothorax (OPTX) is defined as air in the pleural space that was not suspected on plain chest X-ray but detected on CT. Controversy exists in the management of OPTX, especially in patients who require positive pressure ventilation (PPV). In this study, we investigated the need for tube thoracostomy (TT) in blunt trauma patients with OPTX., Materials and Methods: This is a retrospective study of blunt trauma patients of all ages with evidence of OPTX, treated in the Shamir Medical Center Trauma Unit between 2008 and 2017. Two groups were defined. Group I consisted of patients requiring PPV. Group II included patients who did not require PPV. We identified the indication for TT insertion (hemothorax, significant pneumothorax, and enlarging pneumothorax). Necessity for delayed TT insertion due to enlarging pneumothorax was analyzed., Results: Overall 512 patients with traumatic pneumothorax were admitted. 197 (38.5%) had OPTX. Motor vehicle accidents and falls from height accounted for most of the injuries, 47.2 and 42.6%, respectively. Fifty-seven patients required PPV. TT was required in 31 (15.7%) patients. No differences were found between the overall rate of TT insertion between the groups (15.7 vs. 21.1%; p = 0.2) and for delayed insertion of a TT due to an enlarging pneumothorax (25.0 vs. 42.1%; p = 0.45)., Conclusion: TT is not indicated in every patient with OPTX even in case of mechanical ventilation., (© 2021. Springer-Verlag GmbH Germany, part of Springer Nature.)
- Published
- 2022
- Full Text
- View/download PDF
44. Myocarditis after BNT162b2 Vaccination in Israeli Adolescents.
- Author
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Mevorach D, Anis E, Cedar N, Hasin T, Bromberg M, Goldberg L, Parnasa E, Dichtiar R, Hershkovitz Y, Ash N, Green MS, Keinan-Boker L, and Alroy-Preis S
- Subjects
- Adolescent, Child, Female, Humans, Incidence, Israel epidemiology, Male, Myocarditis chemically induced, Risk, Sex Distribution, BNT162 Vaccine adverse effects, Hospitalization statistics & numerical data, Immunization, Secondary adverse effects, Myocarditis epidemiology
- Published
- 2022
- Full Text
- View/download PDF
45. The contribution of potentially modifiable risk factors to acute ischemic stroke burden - Comparing young and older adults.
- Author
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Libruder C, Ram A, Hershkovitz Y, Karolinsky D, Tanne D, Bornstein NM, and Zucker I
- Subjects
- Aged, Case-Control Studies, Humans, Risk Factors, Young Adult, Diabetes Mellitus epidemiology, Hypertension complications, Hypertension epidemiology, Ischemic Stroke, Stroke epidemiology
- Abstract
Stroke is a leading cause of death and disability. In order to estimate the contribution of five modifiable risk factors to acute ischemic stroke (AIS) incidence in Israel, we conducted a case-control study based on first AIS cases aged 21-90 reported to the Israeli National Stroke Registry during 2014-2015, and controls from a national health survey conducted between 2013 and 2015. We calculated the population attributable risk (PAR) of each risk factor and the combined PAR for all risk factors (hypertension, diabetes, current smoking, obesity and hyperlipidemia), in all study population and by subgroups of young adults (age < 55) and older adults (age ≥ 55). The final analysis included 571, 577 and 500 matched pairs for all study population, young adults and older adults, respectively. Among young adults, current smoking and hypertension were the two most contributing risk factors for AIS, accounting for 33.6% (95% CI 27.3-39.9) and 28.9% (95% CI 22.1-35.7) of AIS cases, respectively. Among older adults, hypertension was the single most contributing risk factor for AIS and diabetes was the second most contributing risk factor for AIS, accounting for 64.9% (95% CI 57.3-72.5) and 25.7% (95% CI 17.5-33.9) of AIS cases, respectively. The combined PAR was significantly lower among young adults (PAR = 67.9%), compared with older adults (PAR = 80.7%). The combined PAR for all study population was 80.1% (95% CI 74.0-86.2), indicating that five common and modifiable risk factors explain ~80% of AIS incidence in Israel. Primary prevention strategies targeting these risk factors have the potential to drastically reduce stroke related morbidity and mortality., (Copyright © 2021 Elsevier Inc. All rights reserved.)
- Published
- 2022
- Full Text
- View/download PDF
46. Is Diffuse Axonal Injury Different in Adults and Children? An Analysis of National Trauma Database.
- Author
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Hershkovitz Y, Kessel B, Dubose JJ, Peleg K, Zilbermints V, Jeroukhimov I, Givon A, Dudkiewicz M, and Aranovich D
- Subjects
- Adolescent, Adult, Child, Humans, Injury Severity Score, Registries, Retrospective Studies, Diffuse Axonal Injury epidemiology, Wounds, Nonpenetrating
- Abstract
Background: Diffuse axonal injury (DAI) is typically associated with significant mechanisms of injury and the effects of acceleration-deceleration forces on brain tissues. The prognosis of DAI remains a matter of active investigation, but little is known about outcome differences between adult and pediatric populations with DAI., Methods: We performed a retrospective cohort study involving blunt trauma patients with DAI between the years 1997 and 2018 from the Israeli National Trauma Registry. The patients were divided to pediatric (age <15 years) and adult (age >15 years) groups, with subsequent comparison of demographics and outcomes., Results: Diffuse axonal injury was identified in 1983 patients, including 469 pediatric victims (23.6%) and 1514 adults (76.4%). Adults had higher Injury Severity Score (20.5% vs 13.2%, P = 0.0004), increased mortality (17.7% vs 13.4%, P < 0.0001), longer hospitalizations (58.4% vs 44.4%, P < 0.001), and higher rehabilitation need rates (56.4% vs 41.8%, P < 0.0001). Associated extracranial injuries were also more common in adults, particularly to the chest., Conclusions: Pediatric patients with DAI have improved outcomes and fewer associated injuries than adult counterparts., Competing Interests: Disclosure: The authors report no conflict of interest., (Copyright © 2022 Wolters Kluwer Health, Inc. All rights reserved.)
- Published
- 2022
- Full Text
- View/download PDF
47. Manual Closed Reduction of Incarcerated Hernia: Is It Safe in the Emergency Department?
- Author
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Hershkovitz Y, Zager Y, Segal B, and Klein Y
- Subjects
- Emergency Medical Services methods, Emergency Service, Hospital statistics & numerical data, Female, Humans, Israel epidemiology, Male, Middle Aged, Outcome and Process Assessment, Health Care, Reoperation methods, Reoperation statistics & numerical data, Retrospective Studies, Risk Adjustment methods, Risk Factors, Hernia, Abdominal complications, Hernia, Abdominal diagnosis, Hernia, Abdominal epidemiology, Hernia, Abdominal surgery, Herniorrhaphy adverse effects, Herniorrhaphy methods, Herniorrhaphy statistics & numerical data, Intestinal Perforation diagnosis, Intestinal Perforation etiology, Intestinal Perforation surgery, Laparotomy adverse effects, Laparotomy methods, Postoperative Complications diagnosis, Postoperative Complications surgery
- Abstract
Background: Emergency surgical repair is the standard approach to the management of an incarcerated abdominal wall hernia (IAWH). In cases of very high-risk patients, manual closed reduction (MCR) of IAWH may prevent the need for emergency surgery., Objectives: To evaluate the safety, success rate, and complications of MCR in the management of IAWH conducted in an emergency department., Methods: The data of all patients who underwent MCR between 2012 and 2018 were retrospectively collected. Patient demographics, presenting symptoms, clinical parameters, and management during the hospitalization were retrieved from the medical charts., Results: Overall, 548 patients underwent MCR during the study period. The success rate was 25.4% (139 patients). One patient had a complication that required a laparotomy 2 days after his discharge. A recurrent incarceration occurred in 23%, 60% of them underwent successful repeated MCR and the others underwent emergency surgery. Six patients (1.4%) had a bowel perforation after a failed MCR., Conclusions: MCR can be performed safely in the emergency department and should be consider as an option to treat IAWH, especially in high operative risk patients.
- Published
- 2022
48. Under-diagnosis of SARS-CoV-2 infections among children aged 0-15 years, a nationwide seroprevalence study, Israel, January 2020 to March 2021.
- Author
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Indenbaum V, Lustig Y, Mendelson E, Hershkovitz Y, Glatman-Freedman A, Keinan-Boker L, and Bassal R
- Subjects
- Adolescent, Antibodies, Viral, COVID-19 Vaccines, Child, Humans, Israel epidemiology, SARS-CoV-2, Seroepidemiologic Studies, COVID-19
- Abstract
Until recently, children and adolescents were not eligible for COVID-19 vaccination. They may have been a considerable source of SARS-CoV-2 spread. We evaluated SARS-CoV-2 IgG antibody seroprevalence in Israeli children aged 0-15 years from January 2020 to March 2021. Seropositivity was 1.8-5.5 times higher than COVID-19 incidence rates based on PCR testing. We found that SARS-CoV-2 infection among children is more prevalent than previously thought and emphasise the importance of seroprevalence studies to accurately estimate exposure.
- Published
- 2021
- Full Text
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49. Effectiveness of BNT162b2 Vaccine in Adolescents during Outbreak of SARS-CoV-2 Delta Variant Infection, Israel, 2021.
- Author
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Glatman-Freedman A, Hershkovitz Y, Kaufman Z, Dichtiar R, Keinan-Boker L, and Bromberg M
- Subjects
- Adolescent, BNT162 Vaccine, COVID-19 Vaccines, Disease Outbreaks, Humans, Israel epidemiology, SARS-CoV-2, COVID-19, Vaccines
- Abstract
In Israel, the BNT162b2 vaccine against severe acute respiratory syndrome coronavirus 2 was approved for use in adolescents in June 2021, shortly before an outbreak of B.1.617.2 (Delta) variant-dominant infection. We evaluated short-term vaccine effectiveness and found the vaccine to be highly effective among this population in this setting.
- Published
- 2021
- Full Text
- View/download PDF
50. Diabetes associated risk for mortality increases with time among first stroke survivors - Findings from the Israeli National Stroke Registry.
- Author
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Zamir E, Libruder C, Murad H, Hershkovitz Y, Zamir A, Tanne D, Bornstein NM, and Zucker I
- Subjects
- Female, Humans, Ischemic Stroke epidemiology, Israel, Male, Proportional Hazards Models, Registries, Risk Factors, Sociodemographic Factors, Survivors, Diabetes Mellitus epidemiology, Ischemic Stroke mortality
- Abstract
Background: Diabetes is a major risk factor for ischemic stroke and may affect post-stroke survival. Previous large scale studies of long-term post-stroke survival are limited and most of them excluded older patients from the study population., Objectives: To compare the risk factors and sociodemographic characteristics between first ischemic stroke cases with and without diabetes and to assess the mortality risk associated with diabetes., Methods: Using population-based National Stroke Registry in Israel, all patients hospitalized for a first event of ischemic stroke between the years 2014-2018 were followed for all-cause mortality. Chi-square analysis was used to compare the differences in risk factors, sociodemographic profile and cumulative mortality between patients with and without diabetes. Cox proportional hazards models were used to estimate the hazard ratio for mortality in selected timeframes., Results: Among 41,639 patients with a first event of ischemic stroke, 44.5% were previously diagnosed with diabetes. Diabetic patients were more likely to be males, members of the Arab ethnic group, with lower socioeconomic status and a higher prevalence of cardiovascular comorbidities, anemia, leukocytosis and abnormal kidney function. Diabetes was associated with a higher mortality risk in the first year and long term, but not in the first month following stroke. Diabetes-associated mortality risk interacted with time and age, was higher in younger age and increased with time., Conclusions: Our findings suggest that diabetes is associated with a higher prevalence of comorbidities among patients with first ischemic stroke and with a higher risk for mortality in the mid and long term, which is more profound in younger age., (Copyright © 2021 Elsevier Inc. All rights reserved.)
- Published
- 2021
- Full Text
- View/download PDF
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