206 results on '"Herron, Todd J."'
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2. High-throughput longitudinal electrophysiology screening of mature chamber-specific hiPSC-CMs using optical mapping
3. A multiscale approach for bridging the gap between potency, efficacy, and safety of small molecules directed at membrane proteins
4. Human perinatal stem cell derived extracellular matrix enables rapid maturation of hiPSC-CM structural and functional phenotypes
5. Deficient cMyBP-C protein expression during cardiomyocyte differentiation underlies human hypertrophic cardiomyopathy cellular phenotypes in disease specific human ES cell derived cardiomyocytes
6. Biobank-driven genomic discovery yields new insight into atrial fibrillation biology
7. Highly Mature Human iPSC–Derived Cardiomyocytes as Models for Cardiac Electrophysiology and Drug Testing
8. Contributors
9. Functional cardiac fibroblasts derived from human pluripotent stem cells via second heart field progenitors
10. Mitochondrial oxidative stress contributes to diastolic dysfunction through impaired mitochondrial dynamics
11. Effect of Glucose on 3D Cardiac Microtissues Derived from Human Induced Pluripotent Stem Cells
12. Cardiac Kir2.1 and NaV1.5 Channels Traffic Together to the Sarcolemma to Control Excitability
13. Abstract 20561: Detecting Pre-Clinical Pro-Arrhythmia Risk in vitro Using Mature Human Induced Pluripotent Stem Cell Derived Cardiomyocyte Monolayers in a Quantitative Electrophysiological High Content Screen
14. Abstract 17734: Functional Cardiac Fibroblasts Derived From Human Pluripotent Stem Cells via Second Heart Field Progenitors
15. Abstract 16704: Epigenetic and Morphofunctional Changes in Human Induced Pluripotent Stem Cell-derived Cardiomyocytes Carrying a Mutation Causative of Premature Aging
16. SNTA1 gene rescues ion channel function and is antiarrhythmic in cardiomyocytes derived from induced pluripotent stem cells from muscular dystrophy patients
17. Author response: SNTA1 gene rescues ion channel function and is antiarrhythmic in cardiomyocytes derived from induced pluripotent stem cells from muscular dystrophy patients
18. 57 - High-Throughput Optical Mapping of Two-Dimensional hiPSC-CM Platforms for Drug Discovery and Cardiotoxicity Testing
19. SNTA1 GeneRescues Ion Channel Function in Cardiomyocytes Derived from Induced Pluripotent Stem Cells Reprogrammed from Muscular Dystrophy Patients with Arrhythmias
20. Purkinje cell calcium dysregulation is the cellular mechanism that underlies catecholaminergic polymorphic ventricular tachycardia
21. In vitro model of ischemic heart failure using human induced pluripotent stem cell–derived cardiomyocytes
22. Loss of H3K4 methylation destabilizes gene expression patterns and physiological functions in adult murine cardiomyocytes
23. From atoms to cells: bridging the gap between potency, efficacy, and safety of small molecules directed at a membrane protein
24. Power output is linearly related to MyHC content in rat skinned myocytes and isolated working hearts
25. Abnormal myocardial expression of SAP97 is associated with arrhythmogenic risk
26. Upregulation of the MAGUK Sap97 Enhances Protein Expression in Stem Cell Derived Myocytes
27. Detection of Drug-Induced Torsades de Pointes Arrhythmia Mechanisms Using hiPSC-CM Syncytial Monolayers in a High-Throughput Screening Voltage Sensitive Dye Assay
28. Single histidine-substituted cardiac troponin I confers protection from age-related systolic and diastolic dysfunction
29. Modulation of Cardiac Performance by Motor Protein Gene Transfer
30. 57 - Highly Mature Human iPSC–Derived Cardiomyocytes as Models for Cardiac Electrophysiology and Drug Testing
31. Contributors
32. Brugada syndrome trafficking-defective Nav1.5 channels can trap cardiac Kir2.1/2.2 channels
33. HDAC inhibitor valproic acid protects heart function through Foxm1 pathway after acute myocardial infarction
34. Role of complement C5a and histones in septic cardiomyopathy
35. Bipolar Patient Specific In vitroDiagnostic Test Reveals Underlying Cardiac Arrhythmia Phenotype Caused by Calcium Channel Genetic Risk Factor
36. Detection of Drug-Induced Torsades de Pointes Arrhythmia Mechanisms Using hiPSC-CM Syncytial Monolayers in a High-Throughput Screening Voltage Sensitive Dye Assay.
37. Brugada syndrome trafficking–defective Nav1.5 channels can trap cardiac Kir2.1/2.2 channels
38. Cardiac Kir2.1 and Na V 1.5 Channels Traffic Together to the Sarcolemma to Control Excitability
39. Genome-wide association study of 1 million people identifies 111 loci for atrial fibrillation
40. Genome-wide Study of Atrial Fibrillation Identifies Seven Risk Loci and Highlights Biological Pathways and Regulatory Elements Involved in Cardiac Development
41. HDAC Inhibitor Valproic Acid Protects Heart Function Through Foxm1 Pathway after Acute Myocardial Infarction
42. hiPSC-CM Monolayer Maturation State Determines Drug Responsiveness in High Throughput Pro-Arrhythmia Screen
43. Complement Destabilizes Cardiomyocyte Function in Vivo after Polymicrobial Sepsis and In Vitro 2
44. Designing heart performance by gene transfer
45. 491: Effect of high glucose level on the development of human 3D cardiac micro-tissues derived from induced pluripotent stem cells
46. 492: Effect of high glucose level on the function of human 3D cardiac micro-tissues derived from induced pluripotent stem cells
47. Functional cardiac fibroblasts derived from human pluripotent stem cells via second heart field progenitors.
48. Loaded shortening and power output in cardiac myocytes are dependent on myosin heavy chain isoform expression
49. Myosin light chain 2-based selection of human iPSC-derived early ventricular cardiac myocytes
50. Complement Destabilizes Cardiomyocyte Function In Vivo after Polymicrobial Sepsis and In Vitro
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