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3. Consensus document on the prevention of methylmercury exposure in Spain: Study group for the prevention of Me-Hg exposure in Spain (GEPREM-Hg)

Author

González-Estecha, Montserrat, Bodas-Pinedo, Andrés, Guillén-Pérez, José Jesús, Rubio-Herrera, Miguel Ángel, Martínez-Álvarez, Jesús Román, Herráiz-Martínez, Miguel Ángel, Martell-Claros, Nieves, Ordóñez-Iriarte, José Mª, Sáinz-Martín, María, Farré-Rovira, Rosaura, Martínez-Astorquiza, Txantón, García-Donaire, José Antonio, Calvo-Manuel, Elpidio, Bretón-Lesmes, Irene, Prieto-Menchero, Santiago, Llorente-Ballesteros, Mª Teresa, Martínez-García, Mª José, Moreno-Rojas, Rafael, Salas-Salvadó, Jordi, Bermejo-Barrera, Pilar, Cuadrado-Cenzual, Mª Ángeles, Gallardo-Pino, Carmen, Fuentes, María Blanco, Torres-Moreno, Miriam, Trasobares-Iglesias, Elena M., Martín, Bernardino Barceló, Arroyo-Fernández, Manuel, and Calle-Pascual, Alfonso

Published
2015
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5. Exposición al metilmercurio en la población general; toxicocinética; diferencias según el sexo, factores nutricionales y genéticos.

Author

González-Estecha, Montserrat, Bodas-Pinedo, Andrés, Guillén-Pérez, José Jesús, Rubio-Herrera, Miguel Ángel, Ordóñez-Iriarte, José Ma, Trasobares-Iglesias, Elena M., Martell-Claros, Nieves, Martínez-Álvarez, Jesús Román, Farré-Rovira, Rosaura, Herráiz-Martínez, Miguel Angel, Martínez-Astorquiza, Txantón, Calvo-Manuel, Elpidio, Sáinz-Martín, María, Bretón-Lesmes, Irene, Prieto-Menchero, Santiago, Llorente-Ballesteros, Ma Teresa, Martínez-García, Ma José, Salas-Salvadó, Jordi, Bermejo-Barrera, Pilar, and García-Donaire, José Antonio

Subjects
*METHYLMERCURY, *TOXINS, *GENDER studies, *NUTRITION, *GENETICS, *MERCURY in the body, *UNSATURATED fatty acids
Abstract

Mercury is an environmental toxicant that causes numerous adverse effects on human health and natural ecosystems. The factors that determine the existance of adverse effects, as well as their severity are, among others: the chemical form of mercury (elemental, inorganic, organic), dosis, age, period of exposure, pathways of exposure and environmental, nutritional and genetic factors. In the aquatic cycle of mercury, once it has been deposited, it is transformed into methylmercury due to the action of certain sulphate-reducing bacteria, which bioaccumulates in the aquatic organisms and moves into the food chain. The methylmercury content of large, long-lived fish such as swordfish, shark, tuna or marlin, is higher. Methylmercury binds to protein in fish and is therefore not eliminated by cleaning or cooking the fish. Fetuses and small children are more vulnerable to the neurotoxic effects of methylmercury from the consumption of contaminated fish. Methylmercury is absorbed in the gastrointestinal tract and crosses the blood-brain barrier and the placenta. The intake of certain dietary components such as polyunsaturated fatty acids, selenium, fiber, thiol compounds, certain phytochemicals and other nutrients can modify methylmercury bioaccesibility and its toxicity. Apart from environmental factors, genetic factors can influence mercury toxicity and explain part of the individual vulnerability. [ABSTRACT FROM AUTHOR]

Published
2014
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