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A case report from Shandong University of Traditional Chinese Medicine discusses a 25-year-old woman with atypical hand herpes zoster, a rare skin disease often misdiagnosed as hand eczema. The patient received thread fragrant moxibustion treatment, which resulted in significant improvement in symptoms and skin condition. The study highlights the challenges of diagnosing herpes zoster in unusual locations and the effectiveness of traditional Chinese medicine in treating the condition. [Extracted from the article]

A study conducted at Isfahan University of Medical Sciences focused on herpes zoster ophthalmicus, specifically examining a case involving acute retrobulbar optic neuritis and abducens nerve palsy. The research highlighted the rare occurrence of optic nerve involvement with sixth nerve palsy in cases of ocular herpes zoster, which was successfully treated with corticosteroids and valacyclovir. This case report provides valuable insights into the complexities of herpes zoster ophthalmicus and its potential complications, offering important information for medical professionals and researchers in the field. [Extracted from the article]

The research from Huazhong University of Science and Technology focuses on post-marketing safety surveillance for the recombinant zoster vaccine (Shingrix) to prevent herpes zoster and its complications in older adults. The study analyzed adverse event reports submitted to the Vaccine Adverse Event Reporting System (VAERS) in the United States from October 2017 to April 2024. The findings indicated that the safety profile of the vaccine was reassuring and consistent with clinical trials, with most adverse events being non-serious and commonly reported side effects including injection site reactions, pyrexia, chills, headache, and fatigue. Further studies are recommended to continue generating real-world safety data. [Extracted from the article]

A recent study from the Department of Ophthalmology in Mie, Japan, focused on a case of repeated tube exposure in a patient with neovascular glaucoma after Ahmed valve implantation, due to masked herpes zoster ophthalmicus (HZO). The patient's intraocular pressure (IOP) was controlled by resuming antiviral treatment and anti-vascular endothelial growth factor injections. The research highlights the importance of considering varicella-zoster virus (VZV) reactivation in cases of tube exposure post-surgery in eyes with neovascular glaucoma. [Extracted from the article]

A recent study conducted by the University of Tokyo in Japan examined the association between child varicella vaccination and herpes zoster occurrence in adults within the same household. The retrospective cohort study found that neither the first nor the second dose of the varicella vaccine in children significantly increased the risk of herpes zoster in adults. The research, which was supported by the Japan Agency for Medical Research and Development and the Ministry of Health, Labour and Welfare, concluded that varicella vaccination in households with a single child did not lead to a higher risk of herpes zoster in adults. [Extracted from the article]

Researchers at Benemerita Autonomous University of Puebla conducted a study on the uncommon presentation of simultaneous Herpes Zoster infection in immunocompetent patients. The study highlighted cases of patients with atypical symptoms and no history of immunosuppression, who responded well to treatment with Acyclovir. This research sheds light on the importance of considering such cases in medical literature, especially in light of recent reports. For more information, readers can refer to the International Journal of Medical Students. [Extracted from the article]

A recent case report from the Second Hospital of Nanjing in China highlighted the rare occurrence of varicella-zoster virus-related cerebral infarction in an AIDS patient. The 33-year-old male patient experienced multiple hospitalizations for neurological complications associated with VZV, ultimately leading to limb paralysis and aphasia. The case underscores the importance of early diagnosis, aggressive management, and continuous monitoring of neurological symptoms in AIDS patients with VZV infection to reduce long-term disability and mortality. [Extracted from the article]

A study conducted at the Second Affiliated Hospital in Xi'an, China, focused on varicella zoster virus-related encephalitis (VZV-RE), a rare condition often misdiagnosed, leading to poor prognosis. The researchers used metagenomic next-generation sequencing (mNGS) to detect and identify the VZV pathogen in cerebrospinal fluid samples, aiding in definitive diagnosis. The study analyzed 28 patients with VZV-RE, highlighting various clinical manifestations and treatment outcomes, emphasizing the importance of mNGS in diagnosing VZV central nervous system infections when traditional methods yield negative results. [Extracted from the article]

Researchers at Marshall University recently reported a unique case of Herpes Zoster (HZ) in an immunosuppressed woman with systemic lupus, leading to chronic leg ulceration and subcutaneous panniculitis. The study highlights the challenges of diagnosing atypical HZ manifestations in immunocompromised individuals and emphasizes the importance of prompt therapy. The ulceration in the patient responded well to valacyclovir treatment, underscoring the significance of recognizing unusual clinicopathologic presentations of HZ in compromised immune systems. [Extracted from the article]

A recent study conducted in Poland by researchers from the School of Public Health focused on public awareness and willingness to vaccinate against the Herpes Zoster virus. The study found that only 47% of respondents were aware of the vaccine, with television being the primary source of information. Factors such as chronic disease status and financial status were associated with awareness and willingness to vaccinate. The researchers concluded that there are significant gaps in public awareness and vaccination rates, suggesting the need for targeted media campaigns and improved access to increase vaccination rates. [Extracted from the article]

Researchers at the Graduate School of Medicine in Osaka, Japan, have conducted a study on the immune response to an adjuvanted recombinant zoster vaccine in Japanese patients with rheumatoid arthritis (RA) receiving upadacitinib. The study aims to examine the effectiveness of the vaccine in this specific population. Despite limitations such as a small sample size and short observation period, the study provides evidence on the effectiveness and tolerability of the vaccine in Japanese patients with RA receiving upadacitinib. For more information, readers can refer to the Journal of Clinical Medicine. [Extracted from the article]

A recent report from Imperial College Healthcare NHS Trust in London, United Kingdom, discusses the case of a child with herpes zoster ophthalmicus, a rare condition involving the trigeminal nerve. The child underwent a magnetic resonance imaging scan that revealed abnormalities in the trigeminal nerve and its branches, a finding not commonly reported in pediatric literature. The researchers aim to raise awareness of this potential imaging feature of herpes zoster ophthalmicus in children, highlighting the need for further study in this area. [Extracted from the article]

The article discusses a newly launched clinical trial, NCT06723080, conducted by Jiangsu vcare pharmaceutical technology co., LTD. The trial aims to evaluate the efficacy and safety of VC005 tablets in adult patients with moderate to severe atopic dermatitis. The study is a multicenter, randomized, double-blind, placebo-controlled phase III clinical trial, with a primary completion date set for August 30, 2027. The trial is currently not yet recruiting participants, with an enrollment target of 480 individuals. [Extracted from the article]

A recent study conducted at the University of Sao Paulo focused on using Diffusion Tensor Imaging (DTI) to examine the spinal cord of patients with neuropathic pain secondary to Herpes Zoster infection. The research aimed to identify microstructural changes associated with postherpetic neuralgia (PHN) through DTI parameters such as fractional anisotropy (FA) and apparent diffusion coefficient (ADC). The findings suggest that DTI may offer valuable insights into the pathogenesis of neuropathic pain following Herpes Zoster infection, with potential implications for future research in larger cohorts. [Extracted from the article]

A recent study conducted in Taichung, Taiwan, explored the relationship between total knee replacement (TKR) and the risk of herpes zoster (HZ) in osteoarthritis (OA) patients. The research found that OA patients who underwent TKR had a significantly elevated risk of HZ compared to those who did not receive the procedure, especially among females and older adults. The study highlights the importance of monitoring and preventing HZ in patients undergoing major joint surgeries. For more information, the study can be found in the International Journal of Medical Sciences. [Extracted from the article]

Researchers at Peking University conducted a cross-sectional survey in China to assess the knowledge, attitudes, and practices related to herpes zoster (HZ) among the general population, HZ patients, and dermatologists. The study revealed gaps in understanding about the severity, transmission, and prevention of HZ across all groups, highlighting the importance of education and awareness. The research suggests that doctors play a crucial role in supporting HZ prevention initiatives, as most individuals found vaccination more acceptable if recommended by a healthcare professional. This study provides valuable insights for the development of targeted educational interventions and public health strategies against HZ in China. [Extracted from the article]

A recent report from Hebei University in China discusses the challenges of managing herpes zoster-associated pain and highlights emerging non-oral pharmacological interventions such as autologous platelet-rich plasma and sympathetic nerve block. These new therapeutic options offer hope for more effective treatment with less trauma and quicker recovery. The research provides a valuable review of current studies on non-oral drug therapy for herpes zoster-related pain, offering insights into efficacy, safety, and potential mechanisms for clinical treatment. [Extracted from the article]

A recent report from Sri Ramachandra Medical College discusses a rare case of Ogilvie syndrome induced by herpes zoster virus, also known as shingles. The condition, characterized by colonic dilation without mechanical obstruction, is believed to be triggered by autonomic nervous system dysfunction. The study emphasizes the importance of early recognition and treatment of herpes zoster to prevent unnecessary surgical intervention. For more information, the full article can be accessed through PARIPEX INDIAN JOURNAL OF RESEARCH. [Extracted from the article]

A meta-analysis conducted by researchers at Tianjin University of Traditional Chinese Medicine examined the efficacy and safety of brivudine in treating herpes zoster (HZ). The study, which included seven randomized controlled trials, found that brivudine was more effective than the control group in terms of efficacy and reducing the incidence of postherpetic neuralgia. However, the analysis also noted that the evidence on the safety of brivudine was insufficient. This research sheds light on the potential benefits of brivudine in HZ treatment, but further studies are needed to fully understand its safety profile. [Extracted from the article]

A study conducted by Antai Medical Care Corporation Antai Tian-Sheng Memorial Hospital in Taiwan explored the association between organic erectile dysfunction (OED) and the risk of herpes zoster (HZ) and postherpetic neuralgia (PHN) in men. The study found that men with OED had a significantly higher risk of developing HZ and PHN compared to those without OED. The research suggests that OED may serve as a warning sign for individuals at risk of HZ. The study was published in The Aging Male journal and can be accessed for further information. [Extracted from the article]

Researchers at Yaroslavl State Medical University have reported findings on the nature of central nervous system lesions caused by Varicella Zoster virus infections. The study analyzed 47 patients treated at the Infectious Diseases Clinical Hospital of Yaroslavl, revealing that Varicella Zoster virus can lead to meningitis, meningoencephalitis, and encephalitis. The research highlighted the medical and social significance of these central nervous system disorders, with no reported deaths among the patients studied. [Extracted from the article]

A study conducted at Bali Mandara General Hospital examined the characteristics of herpes zoster (shingles) patients from January 2019 to December 2023. The research found that most patients were male, aged between 45-64 years old, with the thoracic region being the most common site of lesions. The study also identified hypertension as the highest risk factor and postherpetic neuralgia as the most common complication among patients. This research provides valuable insights into the demographics and clinical features of herpes zoster cases in the region. [Extracted from the article]

A recent report from Shengli Oilfield Central Hospital in Dongying, China, highlights the complexity and diversity of clinical manifestations of herpes zoster ophthalmicus (HZO), a condition caused by the reactivation of the varicella-zoster virus. The study aims to improve the diagnosis and treatment of HZO to reduce visual damage and provide evidence for precise care. Researchers emphasize the importance of recognizing the varied symptoms of HZO to prevent missed or incorrect diagnoses, ultimately enhancing patients' quality of life. [Extracted from the article]

Researchers at the Mayo Clinic reported a case of disseminated vaccine-strain varicella-zoster virus reactivation in a 16-year-old female with Hodgkin's lymphoma. The patient had received childhood immunization against varicella but developed the reactivated virus years later. The case underscores the importance of distinguishing between wild-type and vaccine-strain herpes zoster through viral genotyping and highlights potential complications in immunized individuals who later become immunosuppressed. The study emphasizes the need for providers to be aware of vaccine virus reactivation and consider appropriate management strategies. [Extracted from the article]

Researchers at Keio University School of Medicine in Tokyo, Japan, have conducted a study on the optimal timing of recombinant herpes zoster virus vaccination for patients with rheumatoid arthritis who are undergoing JAK inhibitor treatment. The study aims to measure varicella zoster virus-specific IgG titers and T cell response in these patients. The research, funded by Pfizer Japan, involves a multicenter, open-label, randomized comparative study with 60 study subjects. The primary endpoint is to compare VZV-specific IgG antibody titers at week 12 with those at baseline in each group. The study has been approved by the Certified Review Board of Keio and follows ethical guidelines. [Extracted from the article]

The research conducted at Technical University Munich (TU Munich) focused on analyzing health claims data to assess vaccination coverage for Influenza, Pneumococcus, and Herpes zoster among older adults in Bavaria, Germany. The study found that vaccination rates for these diseases increased during the COVID-19 pandemic, with a subsequent decrease in Influenza coverage in 2021. The researchers concluded that efforts are needed to sustain and increase vaccination rates as the pandemic effect wanes. [Extracted from the article]