555 results on '"Herold, Marco J"'
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2. Differential in vivo roles of Mpl cytoplasmic tyrosine residues in murine hematopoiesis and myeloproliferative disease
3. Golgi-localized Ring Finger Protein 121 is necessary for MYCN-driven neuroblastoma tumorigenesis
4. Genome-wide CRISPR screening identifies a role for ARRDC3 in TRP53-mediated responses
5. Combined absence of TRP53 target genes ZMAT3, PUMA and p21 cause a high incidence of cancer in mice
6. High expression of oleoyl-ACP hydrolase underpins life-threatening respiratory viral diseases
7. FHL1 promotes chikungunya and o’nyong-nyong virus infection and pathogenesis with implications for alphavirus vaccine design
8. Author Correction: The NK cell granule protein NKG7 regulates cytotoxic granule exocytosis and inflammation
9. Integration of xeno-free single-cell cloning in CRISPR-mediated DNA editing of human iPSCs improves homogeneity and methodological efficiency of cellular disease modeling
10. Functional flexibility and plasticity in immune control of systemic Salmonella infection
11. Epigenetic modulators of B cell fate identified through coupled phenotype-transcriptome analysis
12. Mutations that prevent caspase cleavage of RIPK1 cause autoinflammatory disease
13. Acquired mutations in BAX confer resistance to BH3-mimetic therapy in acute myeloid leukemia
14. Deletion of Gpatch2 does not alter Tnf expression in mice
15. Phosphoproteomics of three exercise modalities identifies canonical signaling and C18ORF25 as an AMPK substrate regulating skeletal muscle function
16. Ubiquitylation of RIPK3 beyond-the-RHIM can limit RIPK3 activity and cell death
17. Ubiquitin-like protein 3 (UBL3) is required for MARCH ubiquitination of major histocompatibility complex class II and CD86
18. Author Correction: Generation of a CRISPR activation mouse that enables modelling of aggressive lymphoma and interrogation of venetoclax resistance
19. Generation of a CRISPR activation mouse that enables modelling of aggressive lymphoma and interrogation of venetoclax resistance
20. Loss of TRP53 reduces but does not overcome dependency of lymphoma cells on MCL-1
21. Absence of pro-survival A1 has no impact on inflammatory cell survival in vivo during acute lung inflammation and peritonitis
22. The BALB/c.mdx62 mouse exhibits a dystrophic muscle pathology and is a novel model of Duchenne muscular dystrophy
23. Supplementary Data Table S3 from Loss-of-Function but Not Gain-of-Function Properties of Mutant TP53 Are Critical for the Proliferation, Survival, and Metastasis of a Broad Range of Cancer Cells
24. Supplementary Data Figure S15 from Loss-of-Function but Not Gain-of-Function Properties of Mutant TP53 Are Critical for the Proliferation, Survival, and Metastasis of a Broad Range of Cancer Cells
25. A novel MYB::PAIP1 oncogenic fusion in pediatric blastic plasmacytoid dendritic cell neoplasm (BPDCN) is dependent on BCL2 expression and is sensitive to venetoclax
26. BCL-XL antagonism selectively reduces neutrophil life span within inflamed tissues without causing neutropenia
27. Loss of TIP60 (KAT5) abolishes H2AZ lysine 7 acetylation and causes p53, INK4A, and ARF-independent cell cycle arrest
28. The transcription factor IRF4 represses proapoptotic BMF and BIM to licence multiple myeloma survival
29. Caspase-2 does not play a critical role in cell death induction and bacterial clearance during Salmonella infection
30. Dystrophin S3059 phosphorylation partially attenuates denervation atrophy in mouse tibialis anterior muscles.
31. Removal of BFL-1 sensitises some melanoma cells to killing by BH3 mimetic drugs
32. Genome-wide CRISPR screening identifies a role for ARRDC3 in TRP53-mediated responses
33. Stuttering associated with a pathogenic variant in the chaperone protein cyclophilin 40
34. TREML4 receptor regulates inflammation and innate immune cell death during polymicrobial sepsis
35. Emerging connectivity of programmed cell death pathways and its physiological implications
36. The ubiquitylation of IL-1β limits its cleavage by caspase-1 and targets it for proteasomal degradation
37. PRMT1-mediated H4R3me2a recruits SMARCA4 to promote colorectal cancer progression by enhancing EGFR signaling
38. Correction to: PRMT1-mediated H4R3me2a recruits SMARCA4 to promote colorectal cancer progression by enhancing EGFR signaling
39. The NK cell granule protein NKG7 regulates cytotoxic granule exocytosis and inflammation
40. Targeting platelets for improved outcome in KRAS-driven lung adenocarcinoma
41. miR17~92 restrains pro-apoptotic BIM to ensure survival of haematopoietic stem and progenitor cells
42. EBV BCL-2 homologue BHRF1 drives chemoresistance and lymphomagenesis by inhibiting multiple cellular pro-apoptotic proteins
43. Potent efficacy of MCL-1 inhibitor-based therapies in preclinical models of mantle cell lymphoma
44. ROCK1 but not LIMK1 or PAK2 is a key regulator of apoptotic membrane blebbing and cell disassembly
45. Loss-of-Function but Not Gain-of-Function Properties of Mutant TP53 Are Critical for the Proliferation, Survival, and Metastasis of a Broad Range of Cancer Cells
46. A1 is induced by pathogen ligands to limit myeloid cell death and NLRP3 inflammasome activation
47. Relative importance of MCL-1's Anti-Apoptotic versus Non-Apoptotic Functions in vivo
48. Characterization of a novel human BFL-1-specific monoclonal antibody
49. Humanized Mcl-1 mice enable accurate preclinical evaluation of MCL-1 inhibitors destined for clinical use
50. Antiapoptotic Mcl-1 is critical for the survival and niche-filling capacity of Foxp3+ regulatory T cells
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